Thomas Quertermous

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Thomas Quertermous

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#280

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Thomas Quertermous

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Medical
Engineering

Thomas Quertermous's Degrees

PhD Biomedical Engineering Stanford University
Masters Biomedical Engineering Stanford University
Bachelors Biomedical Engineering Stanford University

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Thomas Quertermous's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Genetic studies of body mass index yield new insights for obesity biology (2015) (3549)
Biological, Clinical, and Population Relevance of 95 Loci for Blood Lipids (2010) (3485)
Discovery and Refinement of Loci Associated with Lipid Levels (2013) (2475)
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index (2010) (2011)
Hundreds of variants clustered in genomic loci and biological pathways affect human height (2010) (1961)
Defining the role of common variation in the genomic and biological architecture of adult human height (2014) (1805)
A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease (2015) (1567)
Large-scale association analysis identifies new risk loci for coronary artery disease (2012) (1507)
New genetic loci link adipose and insulin biology to body fat distribution (2014) (1227)
Association analyses of 249,796 individuals reveal eighteen new loci associated with body mass index (2010) (1179)
Genome-wide meta-analyses identify multiple loci associated with smoking behavior (2010) (1107)
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution (2010) (897)
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease (2011) (894)
Common variants associated with plasma triglycerides and risk for coronary artery disease (2013) (767)
Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies. (2005) (564)
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study (2015) (532)
Cloning and expression of a cDNA encoding human endothelium-derived relating factor/nitric oxide synthase. (1992) (500)
Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies (2011) (490)
Endothelin-1 transgenic mice develop glomerulosclerosis, interstitial fibrosis, and renal cysts but not hypertension. (1997) (429)
Opportunities and challenges for transcriptome-wide association studies (2019) (401)
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function (2016) (388)
A long non-coding RNA protects the heart from pathological hypertrophy (2014) (376)
Clinical interpretation and implications of whole-genome sequencing. (2014) (365)
Novel Role for the Potent Endogenous Inotrope Apelin in Human Cardiac Dysfunction (2003) (352)
CD47 blocking antibodies restore phagocytosis and prevent atherosclerosis (2016) (351)
The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo. (2005) (349)
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals (2016) (347)
Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements (2017) (337)
Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis (2019) (331)
Cloning of a Unique Lipase from Endothelial Cells Extends the Lipase Gene Family* (1999) (313)
Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis. (2008) (308)
Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders (2013) (299)
Endothelial lipase is a major determinant of HDL level. (2003) (293)
Persistent Donor Cell Gene Expression among Human Induced Pluripotent Stem Cells Contributes to Differences with Human Embryonic Stem Cells (2010) (291)
MicroRNA‐26a is a novel regulator of vascular smooth muscle cell function (2011) (285)
Admixture mapping for hypertension loci with genome-scan markers (2005) (279)
Del-1, an Endogenous Leukocyte-Endothelial Adhesion Inhibitor, Limits Inflammatory Cell Recruitment (2008) (263)
Detailed Physiologic Characterization Reveals Diverse Mechanisms for Novel Genetic Loci Regulating Glucose and Insulin Metabolism in Humans (2010) (262)
Apelin is necessary for the maintenance of insulin sensitivity. (2009) (260)
Stimulation of endothelin-1 gene expression by insulin in endothelial cells. (1991) (253)
Therapeutic lymphangiogenesis with human recombinant VEGF‐C (2002) (243)
A Bivariate Genome-Wide Approach to Metabolic Syndrome (2011) (235)
Cloning of the GATA-binding protein that regulates endothelin-1 gene expression in endothelial cells. (1991) (231)
Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease (2011) (228)
Expression of the potent vasoconstrictor endothelin in the human central nervous system. (1990) (226)
Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms (2017) (224)
Cooperative interaction of GATA-2 and AP1 regulates transcription of the endothelin-1 gene (1995) (211)
Cloning and characterization of developmental endothelial locus-1: An embryonic endothelial cell protein that binds the αvβ3 integrin receptor (1997) (208)
Cloning and expression of a cDNA encoding human endothelium-derived relaxing factor/nitric oxide synthase. (1992) (204)
Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-Wide Association Meta-analysis Involving More Than 22 000 Cases and 60 000 Controls (2010) (203)
Multi-center genetic study of hypertension: The Family Blood Pressure Program (FBPP). (2002) (202)
Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study. (2008) (201)
Mouse Col18a1 is expressed in a tissue-specific manner as three alternative variants and is localized in basement membrane zones. (1995) (201)
Genetic evidence of assortative mating in humans (2017) (199)
Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity. (2017) (199)
Endogenous regulation of cardiovascular function by apelin-APJ. (2009) (190)
Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease (2014) (187)
Transcriptomic Profiling Maps Anatomically Patterned Subpopulations among Single Embryonic Cardiac Cells. (2016) (183)
Cloning of an Immunoglobulin Family Adhesion Molecule Selectively Expressed by Endothelial Cells* (2001) (182)
Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease (2017) (179)
Innovative approaches to plasminogen activator therapy. (1989) (172)
cDNA cloning and chromosomal assignment of the gene encoding endothelin 3. (1989) (168)
Functional analysis of the endothelin-1 gene promoter. Evidence for an endothelial cell-specific cis-acting sequence. (1990) (165)
Structural organization and chromosomal assignment of the gene encoding endothelin. (1989) (163)
Pathway analysis of coronary atherosclerosis. (2005) (163)
Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment (2016) (160)
Prepregnancy Diabetes and Offspring Risk of Congenital Heart Disease (2016) (156)
Regulation of endothelin-1 gene expression by Fos and Jun. (1991) (154)
Disruption of the Apelin-APJ System Worsens Hypoxia-Induced Pulmonary Hypertension (2011) (154)
Apelin decreases lipolysis via G(q), G(i), and AMPK-Dependent Mechanisms. (2011) (149)
In vivo genetic profiling and cellular localization of apelin reveals a hypoxia-sensitive, endothelial-centered pathway activated in ischemic heart failure. (2008) (149)
Characterizing the admixed African ancestry of African Americans (2009) (143)
Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation. (2009) (141)
Tumor necrosis factor increases transcription of the heparin-binding epidermal growth factor-like growth factor gene in vascular endothelial cells. (1992) (135)
Metabolic syndrome and early-onset coronary artery disease: is the whole greater than its parts? (2006) (133)
Endothelial Lipase Modulates Susceptibility to Atherosclerosis in Apolipoprotein-E-deficient Mice* (2004) (132)
Del1 Induces Integrin Signaling and Angiogenesis by Ligation of αVβ3* (1999) (132)
cDNA cloning and chromosomal assignment of the endothelin 2 gene: vasoactive intestinal contractor peptide is rat endothelin 2. (1991) (129)
Platelet Endothelial Aggregation Receptor 1 (PEAR1), a Novel Epidermal Growth Factor Repeat-containing Transmembrane Receptor, Participates in Platelet Contact-induced Activation* (2005) (128)
Apelin-APJ Signaling Is a Critical Regulator of Endothelial MEF2 Activation in Cardiovascular Development (2013) (126)
NHLBI workshop report: endothelial cell phenotypes in heart, lung, and blood diseases. (2001) (126)
Identification of endothelial cell genes by combined database mining and microarray analysis. (2003) (125)
Hepatic proprotein convertases modulate HDL metabolism. (2007) (124)
Association analyses of East Asian individuals and trans‐ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels (2017) (119)
Human T-cell gamma chain genes: organization, diversity, and rearrangement. (1986) (118)
Trans-Ethnic Fine-Mapping of Lipid Loci Identifies Population-Specific Signals and Allelic Heterogeneity That Increases the Trait Variance Explained (2013) (116)
Neovascularization of ischemic tissues by gene delivery of the extracellular matrix protein Del-1. (2003) (116)
Transcriptional Profiling of the Heart Reveals Chamber-Specific Gene Expression Patterns (2003) (115)
T cell receptor-CD3 complex during early T cell differentiation. Analysis of immature T cell acute lymphoblastic leukemias (T-ALL) at DNA, RNA, and cell membrane level. (1987) (114)
Targeted Disruption of Endothelial Cell-selective Adhesion Molecule Inhibits Angiogenic Processes in Vitro and in Vivo* (2003) (114)
Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes (2013) (113)
Molecular and physiological characterization of RV remodeling in a murine model of pulmonary stenosis. (2008) (113)
Cyclin-dependent kinase inhibitor 2B regulates efferocytosis and atherosclerosis. (2014) (112)
HIF-1 regulates hypoxia- and insulin-induced expression of apelin in adipocytes. (2007) (112)
Dual in vivo magnetic resonance evaluation of magnetically labeled mouse embryonic stem cells and cardiac function at 1.5 t (2006) (112)
Genetic targeting of sprouting angiogenesis using Apln-CreER (2015) (110)
Loss of CDKN2B Promotes p53-Dependent Smooth Muscle Cell Apoptosis and Aneurysm Formation (2013) (109)
Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci (2016) (106)
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution (2011) (104)
Cloning of capsulin, a basic helix-loop-helix factor expressed in progenitor cells of the pericardium and the coronary arteries 1 The sequence reported in this paper has been deposited in the Genbank data base (accession no.: AF029753) 1 (1998) (104)
Coronary Heart Disease-Associated Variation in TCF21 Disrupts a miR-224 Binding Site and miRNA-Mediated Regulation (2014) (101)
Induction of heparin-binding epidermal growth factor-like growth factor mRNA by phorbol ester and angiotensin II in rat aortic smooth muscle cells. (1992) (98)
Spectrum of conditions initially suggesting acute aortic dissection but with negative aortograms. (1986) (98)
Immunoglobulin and T-cell receptor gene rearrangement and expression in human lymphoid leukemia cells at different stages of maturation. (1986) (96)
Regulated expression of endothelial cell-derived lipase. (2000) (96)
Thrombin regulation of mRNA levels of tissue plasminogen activator and plasminogen activator inhibitor-1 in cultured human umbilical vein endothelial cells. (1989) (94)
Human T cell gamma chain joining regions and T cell development. (1987) (93)
Construction and expression of a recombinant antibody-targeted plasminogen activator. (1987) (92)
Myocardial restoration with embryonic stem cell bioartificial tissue transplantation. (2004) (91)
De Novo and Rare Variants at Multiple Loci Support the Oligogenic Origins of Atrioventricular Septal Heart Defects (2016) (90)
Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. (2010) (89)
Polymorphisms in hypoxia inducible factor 1 and the initial clinical presentation of coronary disease. (2007) (89)
Cloning and characterization of developmental endothelial locus-1: an embryonic endothelial cell protein that binds the alphavbeta3 integrin receptor. (1998) (87)
Transcriptional profiling of reporter genes used for molecular imaging of embryonic stem cell transplantation. (2006) (87)
Large-Scale Single-Cell RNA-Seq Reveals Molecular Signatures of Heterogeneous Populations of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells (2018) (86)
Molecular Isolation and Characterization of a Soluble Isoform of Activated Leukocyte Cell Adhesion Molecule That Modulates Endothelial Cell Function* (2004) (86)
Endothelial lipase: a new lipase on the block. (2002) (82)
Signature patterns of gene expression in mouse atherosclerosis and their correlation to human coronary disease. (2005) (82)
Human T-cell γ genes contain N segments and have marked junctional variability (1986) (81)
Statin and -Blocker Therapy and the Initial Presentation of Coronary Heart Disease (2006) (81)
Alternative Progenitor Cells Compensate to Rebuild the Coronary Vasculature in Elabela- and Apj-Deficient Hearts. (2017) (81)
Human T cell gamma-chain gene rearrangements in acute lymphoid and nonlymphoid leukemia: comparison with the T cell receptor beta-chain gene. (1986) (80)
Single-Cell Transcriptomic Profiling of Vascular Smooth Muscle Cell Phenotype Modulation in Marfan Syndrome Aortic Aneurysm (2020) (77)
T cell receptor gene rearrangements define a monoclonal T cell proliferation in patients with T cell lymphocytosis and cytopenia. (1986) (76)
Genetic Variants Associated With Glycine Metabolism and Their Role in Insulin Sensitivity and Type 2 Diabetes (2013) (74)
Endothelial cell specific adhesion molecule (ESAM) localizes to platelet–platelet contacts and regulates thrombus formation in vivo (2009) (73)
A recombinant chimeric plasminogen activator with high affinity for fibrin has increased thrombolytic potency in vitro and in vivo. (1991) (72)
Genetic susceptibility to peripheral arterial disease: a dark corner in vascular biology. (2007) (72)
Circulating chemokines accurately identify individuals with clinically significant atherosclerotic heart disease. (2007) (69)
Cosegregation of the endothelin‐3 locus with blood pressure and relative heart weight in inbred Dahl rats (1994) (68)
The Adhesion Molecule Esam1 Is a Novel Hematopoietic Stem Cell Marker (2009) (68)
Systems Genetics Analysis of Genome-Wide Association Study Reveals Novel Associations Between Key Biological Processes and Coronary Artery Disease (2015) (68)
Disease-Related Growth Factor and Embryonic Signaling Pathways Modulate an Enhancer of TCF21 Expression at the 6q23.2 Coronary Heart Disease Locus (2013) (67)
Glia Maturation Factor-&ggr; Is Preferentially Expressed in Microvascular Endothelial and Inflammatory Cells and Modulates Actin Cytoskeleton Reorganization (2006) (66)
Impact of Combined Deficiency of Hepatic Lipase and Endothelial Lipase on the Metabolism of Both High-Density Lipoproteins and Apolipoprotein B–Containing Lipoproteins (2010) (66)
Network Analysis of Human In-Stent Restenosis (2006) (66)
Insulin resistance independently predicts the progression of coronary artery calcification. (2009) (66)
Genetic epistasis of adiponectin and PPARγ2 genotypes in modulation of insulin sensitivity: a family-based association study (2003) (65)
Genetic regulatory mechanisms of smooth muscle cells map to coronary artery disease risk loci (2018) (65)
Vezf1/DB1 Is an Endothelial Cell-specific Transcription Factor That Regulates Expression of the Endothelin-1 Promoter* (2001) (65)
The embryonic angiogenic factor Del1 accelerates tumor growth by enhancing vascular formation. (2002) (65)
Genome-wide linkage scans for fasting glucose, insulin, and insulin resistance in the National Heart, Lung, and Blood Institute Family Blood Pressure Program: evidence of linkages to chromosome 7q36 and 19q13 from meta-analysis. (2005) (64)
Developmental Endothelial Locus-1 (Del-1), a Novel Angiogenic Protein: Its Role in Ischemia (2004) (63)
Structural organization and chromosomal assignment of the gene encoding the human heparin-binding epidermal growth factor-like growth factor/diphtheria toxin receptor. (1993) (61)
Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease (2008) (60)
Differences in Vascular Bed Disease Susceptibility Reflect Differences in Gene Expression Response to Atherogenic Stimuli (2006) (60)
Immunohistochemical localization of endothelial cell-derived lipase in atherosclerotic human coronary arteries. (2003) (60)
Endothelial APLNR regulates tissue fatty acid uptake and is essential for apelin’s glucose-lowering effects (2017) (59)
FGD5 Mediates Proangiogenic Action of Vascular Endothelial Growth Factor in Human Vascular Endothelial Cells (2012) (59)
Matrix metalloproteinase circulating levels, genetic polymorphisms, and susceptibility to acute myocardial infarction among patients with coronary artery disease. (2007) (58)
Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM (2016) (58)
Endogenous endothelin-1 mediates cardiac hypertrophy and switching of myosin heavy chain gene expression in rat ventricular myocardium. (1996) (57)
Ontogeny of apelin and its receptor in the rodent gastrointestinal tract (2009) (55)
Del1 mediates VSMC adhesion, migration, and proliferation through interaction with integrin alpha(v)beta(3). (2001) (55)
Tree-structured supervised learning and the genetics of hypertension. (2004) (55)
Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease (2021) (54)
Measurement of insulin-mediated glucose uptake: direct comparison of the modified insulin suppression test and the euglycemic, hyperinsulinemic clamp. (2013) (53)
Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene. (2015) (53)
Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene. (2016) (52)
Cloning and sequence analysis of complementary DNA encoding an aberrantly rearranged human T-cell gamma chain. (1986) (51)
Statin and beta-blocker therapy and the initial presentation of coronary heart disease. (2006) (51)
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap (2015) (51)
Coronary artery disease associated transcription factor TCF21 regulates smooth muscle precursor cells that contribute to the fibrous cap (2015) (51)
An evaluation of the metabolic syndrome in a large multi-ethnic study: the Family Blood Pressure Program (2005) (50)
Properties of structural variants and short tandem repeats associated with gene expression and complex traits (2020) (50)
Cloning and characterization of a basic helix-loop-helix protein expressed in early mesoderm and the developing somites. (1994) (50)
Cardiovascular Risks in Patients with COVID-19: Potential Mechanisms and Areas of Uncertainty (2020) (49)
Measuring the human T cell receptor gamma-chain locus. (1987) (48)
Molecular signatures determining coronary artery and saphenous vein smooth muscle cell phenotypes: distinct responses to stimuli. (2006) (48)
Opposing cardiovascular roles for the angiotensin and apelin signaling pathways. (2006) (48)
Apelin Enhances Directed Cardiac Differentiation of Mouse and Human Embryonic Stem Cells (2012) (47)
Genome-wide expression profiling of a cardiac pressure overload model identifies major metabolic and signaling pathway responses. (2004) (47)
Association of polymorphisms in platelet and hemostasis system genes with acute myocardial infarction. (2007) (47)
Epigenetic response to environmental stress: Assembly of BRG1-G9a/GLP-DNMT3 repressive chromatin complex on Myh6 promoter in pathologically stressed hearts. (2016) (46)
Comparison of T cell receptor gene rearrangements in patients with large granular T cell leukemia and Felty's syndrome. (1987) (46)
Biethnic comparisons of autosomal genomic scan for loci linked to plasma adiponectin in populations of Chinese and Japanese origin. (2004) (45)
Mouse Strain–Specific Differences in Vascular Wall Gene Expression and Their Relationship to Vascular Disease (2004) (45)
Binding of tissue-type plasminogen activator with human endothelial cell monolayers. Characterization of the high affinity interaction with plasminogen activator inhibitor-1. (1990) (45)
A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease. (2008) (44)
Coronary Disease-Associated Gene TCF21 Inhibits Smooth Muscle Cell Differentiation by Blocking the Myocardin-Serum Response Factor Pathway (2019) (44)
Early somatic mosaicism is a rare cause of long-QT syndrome (2016) (44)
Characterization of TCF21 Downstream Target Regions Identifies a Transcriptional Network Linking Multiple Independent Coronary Artery Disease Loci (2015) (43)
TCF21 and the environmental sensor aryl-hydrocarbon receptor cooperate to activate a pro-inflammatory gene expression program in coronary artery smooth muscle cells (2017) (43)
Endothelial Lipase Modulates Monocyte Adhesion to the Vessel Wall (2004) (43)
Replication of genome‐wide association signals of type 2 diabetes in Han Chinese in a prospective cohort (2012) (42)
Common ALDH2 genetic variants predict development of hypertension in the SAPPHIRe prospective cohort: Gene-environmental interaction with alcohol consumption (2012) (42)
Plasminogen Activators: The Old and the New (1989) (41)
Pacemaker failure resulting from radiation damage. (1983) (40)
Two Major QTLs and Several Others Relate to Factors of Metabolic Syndrome in the Family Blood Pressure Program (2005) (40)
Endothelial lipase is increased by inflammation and promotes LDL uptake in macrophages. (2007) (40)
Provocative pattern of rearrangements of the genes for the gamma and beta chains of the T-cell receptor in human leukemias. (1987) (39)
Proteomic profiles of serum inflammatory markers accurately predict atherosclerosis in mice. (2006) (39)
Oxido-reductive regulation of vascular remodeling by receptor tyrosine kinase ROS1. (2014) (39)
Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD (2008) (38)
Upregulation of the apelin-APJ pathway promotes neointima formation in the carotid ligation model in mouse. (2010) (38)
Endothelial cell-selective adhesion molecule modulates atherosclerosis through plaque angiogenesis and monocyte-endothelial interaction. (2010) (38)
Increased expression of endothelial lipase in rat models of hypertension. (2005) (38)
Recombinant antibodies possessing novel effector functions. (1989) (38)
An updated meta-analysis of genome scans for hypertension and blood pressure in the NHLBI Family Blood Pressure Program (FBPP). (2006) (38)
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk (2018) (37)
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study (2016) (37)
Pathological Ace2-to-Ace enzyme switch in the stressed heart is transcriptionally controlled by the endothelial Brg1–FoxM1 complex (2016) (37)
TCF21 and AP-1 interact through epigenetic modifications to regulate coronary artery disease gene expression (2019) (37)
Nat1 Deficiency Is Associated with Mitochondrial Dysfunction and Exercise Intolerance in Mice. (2016) (36)
Octamer-dependent in Vivo Expression of the Endothelial Cell-specific TIE2 Gene* (1999) (36)
Transcriptome Alteration in the Diabetic Heart by Rosiglitazone: Implications for Cardiovascular Mortality (2008) (36)
Left ventricular ejection fraction. Physician estimates compared with gated blood pool scan measurements. (1988) (36)
Coronary risk assessment among intermediate risk patients using a clinical and biomarker based algorithm developed and validated in two population cohorts (2012) (36)
Cardiovascular overexpression of transforming growth factor-beta(1) causes abnormal yolk sac vasculogenesis and early embryonic death. (2000) (36)
Identification of ARIA regulating endothelial apoptosis and angiogenesis by modulating proteasomal degradation of cIAP-1 and cIAP-2 (2009) (35)
Cardiac pressure overload hypertrophy is differentially regulated by β-adrenergic receptor subtypes. (2011) (35)
Modulation of mRNA levels for urinary- and tissue-type plasminogen activator and plasminogen activator inhibitors 1 and 2 in human fibroblasts by interleukin 1. (1989) (35)
Genome-wide expression dynamics during mouse embryonic development reveal similarities to Drosophila development. (2005) (35)
Effect of chemical conjugation of recombinant single-chain urokinase-type plasminogen activator with monoclonal antiplatelet antibodies on platelet aggregation and on plasma clot lysis in vitro and in vivo. (1991) (34)
Transcriptional profiling of in vitro smooth muscle cell differentiation identifies specific patterns of gene and pathway activation. (2004) (34)
Genetics and Genomics of Coronary Artery Disease (2016) (32)
Trans-ethnic fine mapping identifies a novel independent locus at the 3′ end of CDKAL1 and novel variants of several susceptibility loci for type 2 diabetes in a Han Chinese population (2013) (32)
Functional analysis of the endothelial cell-specific Tie2/Tek promoter identifies unique protein-binding elements. (1998) (32)
Regional and maturation-associated expression of endothelin 2 in rat gastrointestinal tract. (1995) (32)
Role of endothelin in a rabbit model of acute myocardial infarction: effects of receptor antagonists. (1996) (32)
Genomic profiling of human vascular cells identifies TWIST1 as a causal gene for common vascular diseases (2020) (31)
Inducible and selective transgene expression in murine vascular endothelium. (2002) (31)
Systems Genomics Identifies a Key Role for Hypocretin/Orexin Receptor-2 in Human Heart Failure. (2015) (31)
Regional variability in preproEndothelin-1 gene expression in sheep pulmonary artery and lung during the onset of air-induced chronic pulmonary hypertension. Participation Of arterial smooth muscle cells. (1998) (30)
Chromatin Remodeling Pathways in Smooth Muscle Cell Differentiation, and Evidence for an Integral Role for p300 (2010) (30)
Admixture mapping of quantitative trait loci for blood lipids in African-Americans. (2009) (29)
An autosomal genome-wide scan for loci linked to pre-diabetic phenotypes in nondiabetic Chinese subjects from the Stanford Asia-Pacific Program of Hypertension and Insulin Resistance Family Study. (2005) (29)
In vivo molecular MRI of cell survival and teratoma formation following embryonic stem cell transplantation into the injured murine myocardium (2011) (29)
Increased bone mass in mice lacking the adipokine apelin. (2013) (29)
Targeted inactivation of endothelial lipase attenuates lung allergic inflammation through raising plasma HDL level and inhibiting eosinophil infiltration. (2009) (28)
Apelin and its g protein-coupled receptor regulate cardiac development as well as cardiac function. (2007) (28)
High-sensitivity cardiac troponin I and incident coronary heart disease among asymptomatic older adults (2016) (28)
PCSK6 Is a Key Protease in the Control of Smooth Muscle Cell Function in Vascular Remodeling (2020) (28)
Peroxisome Proliferator-Activated Receptor Gamma Polymorphisms and Coronary Heart Disease (2009) (28)
Advances in Transcriptomics: Investigating Cardiovascular Disease at Unprecedented Resolution. (2018) (27)
FAM13A affects body fat distribution and adipocyte function (2020) (27)
Susceptibility Loci for Clinical Coronary Artery Disease and Subclinical Coronary Atherosclerosis Throughout the Life-Course (2015) (26)
Physical Inactivity is an Important Lifestyle Determinant of Insulin Resistance in Hypertensive Patients (2004) (26)
Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci. (2016) (26)
Sagittal abdominal diameter is associated with insulin sensitivity in Chinese hypertensive patients and their siblings (2003) (26)
Directed endothelial differentiation of cultured embryonic yolk sac cells in vivo provides a novel cell‐based system for gene therapy (1995) (26)
Trans-ethnic fine-mapping of genetic loci for body mass index in the diverse ancestral populations of the Population Architecture using Genomics and Epidemiology (PAGE) Study reveals evidence for multiple signals at established loci (2017) (25)
Pancreatic Islet APJ Deletion Reduces Islet Density and Glucose Tolerance in Mice. (2015) (25)
Do plasma biomarkers of coagulation and fibrinolysis differ between patients who have experienced an acute myocardial infarction versus stable exertional angina? (2007) (25)
Pulmonary hypoxia increases endothelin-1 gene expression in sheep. (1994) (25)
Identification of an Endothelial Cell-specific Regulatory Region in the Murine Endothelin-1 Gene* (1997) (24)
Genetics of Coronary Artery Disease in Taiwan: A Cardiometabochip Study by the Taichi Consortium (2016) (24)
Sequence to Medical Phenotypes: A Framework for Interpretation of Human Whole Genome DNA Sequence Data (2015) (24)
Apelin and APJ orchestrate complex tissue-specific control of cardiomyocyte hypertrophy and contractility in the hypertrophy-heart failure transition. (2018) (24)
Vulnerabilities of transcriptome-wide association studies (2017) (23)
Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus (2017) (23)
Role of endothelial lipase in plasma HDL levels in a murine model of hypertriglyceridemia. (2009) (22)
Functional Assays to Screen and Dissect Genomic Hits: Doubling Down on the National Investment in Genomic Research. (2018) (21)
Nonlinkage of the T cell receptor α, β, and γ genes to systemic lupus erythematosus in multiplex families (1988) (21)
The environment-sensing aryl-hydrocarbon receptor inhibits the chondrogenic fate of modulated smooth muscle cells in atherosclerotic lesions (2020) (21)
Endothelial lipase is synthesized by hepatic and aorta endothelial cells and its expression is altered in apoE-deficient mice Published, JLR Papers in Press, June 8, 2004. DOI 10.1194/jlr.M400069-JLR200 (2004) (21)
Molecular Signatures Determining Coronary Artery and Saphenous Vein Smooth Muscle Cell Phenotypes: Distinct Responses to Stimuli (2006) (21)
Load-dependent effects of apelin on murine cardiomyocytes (2017) (20)
Sex-specific genetic architecture of human fatness in Chinese: the SAPPHIRe Study (2010) (19)
The negative correlation between plasma adiponectin and blood pressure depends on obesity: a family-based association study in SAPPHIRe. (2008) (19)
Single-nucleus chromatin accessibility profiling highlights regulatory mechanisms of coronary artery disease risk (2022) (19)
The immunoreactive region in a novel autoantigen contains a nuclear localization sequence. (1994) (19)
The angiogenic factor Del1 prevents apoptosis of endothelial cells through integrin binding. (2012) (19)
Generation of Vascular Smooth Muscle Cells From Induced Pluripotent Stem Cells: Methods, Applications, and Considerations. (2021) (19)
Heritability of left ventricular mass in Japanese families living in Hawaii: the SAPPHIRe Study (2007) (18)
Identification of an octamer element required for in vivo expression of the TIE1 gene in endothelial cells. (2001) (18)
Structural integrity of the glycoprotein IIb and IIIa genes in Glanzmann thrombasthenia patients from Israel. (1988) (18)
Pancreatitis activates pancreatic apelin-APJ axis in mice. (2013) (18)
Genetic polymorphisms of PCSK2 are associated with glucose homeostasis and progression to type 2 diabetes in a Chinese population (2015) (17)
Role of endothelial cell-selective adhesion molecule in hematogeneous metastasis. (2010) (17)
Induced Pluripotent Stem Cell-Derived Endothelial Cells in Insulin Resistance and Metabolic Syndrome. (2017) (17)
In Vivo Bioluminescence Imaging of Inducible Nitric Oxide Synthase Gene Expression in Vascular Inflammation (2011) (17)
Environment-Sensing Aryl Hydrocarbon Receptor Inhibits the Chondrogenic Fate of Modulated Smooth Muscle Cells in Atherosclerotic Lesions (2020) (17)
FGF-1 enhanced cardiogenesis in differentiating embryonal carcinoma cell cultures, which was opposite to the effect of FGF-2. (2003) (16)
Genetic variation of SORBS1 gene is associated with glucose homeostasis and age at onset of diabetes: A SAPPHIRe Cohort Study (2018) (16)
Targeting LOXL 2 for cardiac interstitial fibrosis and heart failure treatment (2016) (16)
Effect of heavy chain signal peptide mutations and NH2-terminal chain length on binding of anti-digoxin antibodies. (1993) (15)
Transcriptome-wide association studies: opportunities and challenges (2018) (15)
An “almost exhaustive” search‐based sequential permutation method for detecting epistasis in disease association studies (2010) (15)
Apelin-APJ signaling in retinal angiogenesis. (2008) (14)
The impact of data quality on the identification of complex disease genes: experience from the Family Blood Pressure Program (2006) (14)
A TNF Variant that Associates with Susceptibility to Musculoskeletal Disease Modulates Thyroid Hormone Receptor Binding to Control Promoter Activation (2013) (14)
Genetic Variation in the Human SORBS1 Gene is Associated With Blood Pressure Regulation and Age at Onset of Hypertension (2016) (13)
Genome-wide Linkage Scans for Fasting Glucose , Insulin , and Insulin Resistance in the National Heart , Lung , and Blood Institute Family Blood Pressure Program Evidence of Linkages to Chromosome 7 q 36 and 19 q 13 From Meta-Analysis (2005) (13)
Molecular cloning of nonsecreted endothelial cell-derived lipase isoforms. (2004) (13)
CRP-level-associated polymorphism rs1205 within the CRP gene is associated with 2-hour glucose level: The SAPPHIRe study (2017) (12)
Genetic regulation of endothelin-1 in vascular endothelial cells. (1992) (12)
Predictive network modeling in human induced pluripotent stem cells identifies key driver genes for insulin responsiveness (2020) (12)
The effects of the renin-angiotensin-aldosterone system gene polymorphisms on insulin resistance in hypertensive families (2012) (11)
ZEB2 Shapes the Epigenetic Landscape of Atherosclerosis. (2022) (11)
The combination of 9p21.3 genotype and biomarker profile improves a peripheral artery disease risk prediction model (2014) (11)
Functional activity of the CFTR Cl− channel in human myocardium (2007) (11)
Dissecting the Causal Genetic Mechanisms of Coronary Heart Disease (2014) (11)
Long non-coding RNA gene regulation and trait associations across human tissues (2019) (10)
Human T-cell gamma genes contain N segments and have marked junctional variability. (1986) (10)
Overexpression of the Del1 gene causes dendritic branching in the mouse mesentery. (2005) (10)
Linkage analysis incorporating gene-age interactions identifies seven novel lipid loci: the Family Blood Pressure Program. (2014) (10)
Transcriptomic profiling of experimental arterial injury reveals new mechanisms and temporal dynamics in vascular healing response (2020) (10)
From Locus Association to Mechanism of Gene Causality: The Devil Is in the Details. (2015) (10)
Molecular mechanisms of coronary disease revealed using quantitative trait loci for TCF21 binding, chromatin accessibility, and chromosomal looping (2020) (9)
Cyclin-dependent kinase inhibitor 2B regulates efferocytosis and atherosclerosis. (2019) (9)
The role of insulin as a key regulator of seeding, proliferation, and mRNA transcription of human pluripotent stem cells (2019) (9)
Racial variation in lipoprotein-associated phospholipase A2 in older adults (2011) (9)
Bivariate genome-wide scan for metabolic phenotypes in non-diabetic Chinese individuals from the Stanford, Asia and Pacific Program of Hypertension and Insulin Resistance Family Study (2007) (9)
Genetic variation in the carbonyl reductase 3 gene confers risk of type 2 diabetes and insulin resistance: a potential regulator of adipogenesis (2012) (9)
Enhancer connectome in primary human cells reveals target genes of disease-associated DNA elements (2017) (8)
Epicardial calcineurin-NFAT signals through Smad2 to direct coronary smooth muscle cell and arterial wall development. (2014) (8)
Genome-wide copy number variation analysis identified deletions in SFMBT1 associated with fasting plasma glucose in a Han Chinese population (2017) (8)
Human Coronary Plaque T Cells Are Clonal and Cross-React to Virus and Self (2022) (8)
Effect of Common Genetic Variants of Growth Arrest-Specific 6 Gene on Insulin Resistance, Obesity and Type 2 Diabetes in an Asian Population (2015) (8)
Endothelial cell-specific regulation of the murine endothelin-1 gene. (2000) (8)
Size Fractionation Using Sucrose Gradients (1987) (8)
Genetic Structure of Human Populations (2002) (8)
Coronary Artery Disease and Its Risk Factors: Leveraging Shared Genetics to Discover Novel Biology. (2016) (8)
A novel platform device for rodent echocardiography. (2007) (7)
High-level expression of antibody-plasminogen activator fusion proteins in hybridoma cells. (1993) (7)
Attachment of an antifibrin antibody to the amino terminus of tissue-type plasminogen activator impairs stimulation by Fibrin (1994) (7)
Apelin increases atrial conduction velocity, refractoriness, and prevents inducibility of atrial fibrillation (2020) (7)
Abstract 453: Apelin Regulates Cardiac Contractility and Rescues Neurohormonal Heart Failure (2006) (6)
Nonlinkage of the T cell receptor alpha, beta, and gamma genes to systemic lupus erythematosus in multiplex families. (1988) (6)
Comparison of developmental endothelial locus-1 angiogenic factor with vascular endothelial growth factor in a porcine model of cardiac ischemia. (2003) (6)
Integrative single-cell analysis of cardiogenesis identifies developmental trajectories and non-coding mutations in congenital heart disease (2022) (6)
Increased rate of hair regrowth in mice with constitutive overexpression of Del1. (2008) (6)
Variability in messenger RNA levels in human umbilical vein endothelial cells of different lineage and time in culture (1989) (6)
Approximating the Sum of Independent Non-Identical Binomial Random Variables (2017) (6)
Circulating peptide prevents preeclampsia (2017) (6)
Clinical Utility of a Novel Coronary Heart Disease Risk‐Assessment Test to Further Classify Intermediate‐Risk Patients (2013) (5)
Genomic integrity of human induced pluripotent stem cells across nine studies in the NHLBI NextGen program (2020) (5)
Cell-specific chromatin landscape of human coronary artery resolves regulatory mechanisms of disease risk (2021) (5)
An integrated approach to identify environmental modulators of genetic risk factors for complex traits (2021) (5)
Endothelin Type A Receptor Genotype is a Determinant of Quantitative Traits of Metabolic Syndrome in Asian Hypertensive Families: A SAPPHIRe Study (2013) (5)
Erratum: Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene (American Society for Clinical Investigation (2015)125:4 (1739-1751) DOI 10.1172/JCI74692) (2016) (5)
Smad3 regulates smooth muscle cell fate and mediates adverse remodeling and calcification of the atherosclerotic plaque (2022) (5)
Multi-omics analysis identifies CpGs near G6PC2 mediating the effects of genetic variants on fasting glucose (2021) (5)
Polymerase chain reaction cloning of L‐type calcium channel sequences from the heart and the brain (1990) (5)
Endothelial lipase Published, JLR Papers in Press, September 1, 2002. DOI 10.1194/jlr.R200011-JLR200 (2002) (5)
CRISPR-Cas9-mediated knockout of SPRY2 in human hepatocytes leads to increased glucose uptake and lipid droplet accumulation (2019) (5)
Antibody-targeted thrombolytic agents. (1990) (4)
Use of high throughput genomic tools for the study of endothelial cell biology. (2003) (4)
Metabolic Syndrome and Early-Onset Coronary Artery Disease (2006) (4)
T-cell receptor gene rearrangement and expression in human natural killer cells: natural killer activity is not dependent on the rearrangement and expression of T-cell receptor α, β, or γ genes (2004) (4)
Cloning and characterization of developmental endothelial locus-1: An embryonic endothelial cell protein that binds the (cid:97) v (cid:98) 3 integrin receptor (1997) (4)
Plating and transferring bacteriophage libraries. (2001) (4)
Detailed Functional Characterization of a Waist-Hip Ratio Locus in 7p15.2 Defines an Enhancer Controlling Adipocyte Differentiation (2019) (4)
Author Correction: Single-nucleus chromatin accessibility profiling highlights regulatory mechanisms of coronary artery disease risk (2022) (3)
Frontiers in nephrology: genomic approaches to understanding the molecular basis of atherosclerosis. (2007) (3)
Integration of genetic colocalizations with physiological and pharmacological perturbations identifies cardiometabolic disease genes (2021) (3)
Genetic and Functional Analyses Identify NAT2 as a Human Insulin Sensitivity Gene (2013) (3)
Hybrid molecules: insights into plasminogen activator function. (1991) (3)
AMPA-Type Glutamate Receptors Associated With Vascular Smooth Muscle Cell Subpopulations in Atherosclerosis and Vascular Injury (2021) (3)
Osteomodulin attenuates smooth muscle cell osteogenic transition in vascular calcification (2022) (3)
T-cell receptor gene rearrangement and expression in human natural killer cells: natural killer activity is not dependent on the rearrangement and expression of T-cell receptor alpha, beta, or gamma genes. (1988) (3)
M1661 Regulation of Colonic Trefoil Factor 3 By Apelin (2008) (2)
Size Fractionation Using Agarose Gels (1987) (2)
Smad3 Regulates Smooth Muscle Cell Fate and Governs Adverse Remodeling and Calcification of Atherosclerotic Plaque (2020) (2)
Increasing selectivity of plasminogen activators with antibodies. (1988) (2)
Stanford Cardiovascular Institute. (2019) (2)
Purification of Bacteriophage Clones (1991) (2)
IGF1 Gene Is Associated With Triglyceride Levels In Subjects With Family History Of Hypertension From The SAPPHIRe And TWB Projects (2018) (2)
Insulin Resistance: Regression and Clustering (2014) (2)
Single‐Cell Transcriptomic Census of Endothelial Changes Induced by Matrix Stiffness and the Association with Atherosclerosis (2022) (2)
Abstract 16392: Oxido-Reductive Regulation of Human Vascular Remodeling by the Orphan Receptor Tyrosine Kinase Ros1 (2014) (2)
I mmunohistochemical localization of endothelial cell-derived lipase in atherosclerotic human coronary arteries (2003) (1)
Genome-Wide Expression Dynamics during Mouse Embryonic Development and Organogenesis Reveal Similarities to Drosophila Development (2005) (1)
Study of exonic variation identifies incremental information regarding lipid-related and coronary heart disease genes. (2014) (1)
Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity. (2022) (1)
von Willebrand Factor Is Produced Exclusively by Endothelium, Not Neointima, in Occlusive Vascular Lesions in Both Pulmonary Hypertension and Atherosclerosis. (2022) (1)
Antibody-targeted Plasminogen Activators (1988) (1)
Properties of structural variants and short tandem repeats associated with gene expression and complex traits (2020) (1)
Integration of genetic colocalizations with physiological and pharmacological perturbations identifies cardiometabolic disease genes (2022) (1)
Abstract 17671: TCF21 Regulates Coronary Artery Disease Causing Aryl-hydrocarbon Receptor Gene Expression and its Downstream Pathway Activation by Environmental Ligands (2015) (1)
Absence of evidence for an association between resistin gene variants and insulin resistance in an Asian population with low and high blood pressure. (2008) (1)
Discovery and quality analysis of a comprehensive set of structural variants and short tandem repeats (2020) (1)
Apelin Reduces Pancreatic Inflammation During Acute Pancreatitis (2011) (1)
Mo-P6:419 A common novel SNP in the peroxisome proliferative activated receptor gamma gene is associated with early-onset coronary artery disease (2006) (1)
Galectin-3 and incident heart failure among patients with pre-existing coronary artery disease: The ADVANCE study (2014) (1)
Quantitative trait loci mapped for TCF21 binding, chromatin accessibility and chromosomal looping in coronary artery smooth muscle cells reveal molecular mechanisms of coronary disease loci (2020) (1)
The Effect of Apelin on Single Isolated Cardiac Myocytes from Wild-Type and Apelin / APJ KO Mice (2010) (1)
Genomic organization and chromosomal localization of the gene TCF15 encoding the early mesodermal basic helix-loop-helix factor bHLH-EC2. (1995) (1)
Interpreting whole-genome sequencing--reply. (2014) (1)
Abstract 16484: The Transcriptional Repressor NR1D2 is Associated With Congenital Heart Disease and Plays an Evolutionarily Conserved Role in Cardiac Development (2015) (1)
DEL1 Protects Against Osteoarthritis by Preventing Chondrocyte Apoptosis (2012) (1)
Molecular mechanisms of coronary disease revealed using quantitative trait loci for TCF21 binding, chromatin accessibility, and chromosomal looping (2020) (1)
Discovery and Refinement Supplementary (2015) (1)
Abstract 4205: Cardiovascular Risk Profiles Measured at the Same Age in American Immigrant Fathers and Offspring (2006) (1)
3P-0779 Altered expression of endothelial cell-derived lipase in diseased vessel wall and its impact on HDL metabolism (2003) (1)
Embryologic Origin Influences Smooth Muscle Cell Phenotypic Modulation Signatures in Murine Marfan Syndrome Aortic Aneurysm (2022) (1)
Distribution of the number of false discoveries in large-scale family-based association testing with application to the association between PTPN1 and hypertension and obesity (2011) (1)
Abstract 17892: Network-Driven Integrative Genomics Analysis of the Cardiogram Gwas Reveals Key Drivers and Subnetworks of Coronary Artery Disease (2011) (1)
Abstract 150: Identification of SYNPO2, SYNM, LMOD1, PDLIM7 and PLN as Novel Markers of Smooth Muscle Cells in Atherosclerosis (2015) (0)
Abstract 538: Single Cell Transcriptional Landscape of Atherosclerosis in Mice and Humans Reveals a Critical Role for Coronary Disease Gene TCF21 (2019) (0)
Abstract 3915: Del-1, A New {beta}2-Integrin Ligand, Which Inhibits Adhesion and Homing of Progenitor Cells (2008) (0)
Single-cell transcriptome dataset of human and mouse in vitro adipogenesis models (2023) (0)
Cloning and tissue-specific expression of cardiac and brain L-type calcium channels (1990) (0)
Su-S3:3 Can high-throughput technologies contribute to cardiovascular risk estimation? (2006) (0)
Abstract 335: Allelic Imbalance at the Coronary Heart Disease Associated Locus 6q23.2 Identifies Causal Variation in the TCF21 Gene (2012) (0)
Abstract P302: Association of High-Sensitive Troponin I With Coronary Heart Disease Incidence Among Asymptomatic Older Adults: The ADVANCE Study (2015) (0)
Abstract 4953: Del-1, a New Beta2-integrin Ligand, Which Inhibits Mobilization, Adhesion and Homing of Progensitor Cells (2009) (0)
Abstract 218: Integration Of Coronary Artery Disease GWAS With Bulk And Single-cell Transcriptomics From Atherosclerotic Plaques By Deconvolution, Reveals Novel Smooth Muscle Cell Genes (2022) (0)
Formation Promotes p53-Dependent Smooth Muscle Cell Apoptosis and Aneurysm CDKN2B Loss of (2013) (0)
Abstract 19297: Susceptibility Loci for Clinical CAD Predispose to Subclinical Coronary Atherosclerosis Throughout the Life Course (2014) (0)
CROP-Seq: a single-cell CRISPRi platform for characterizing candidate genes relevant to metabolic disorders in human adipocytes (2022) (0)
The Epigenomic Landscape of Dilated Cardiomyopathy (2016) (0)
TCF21 and AP-1 interact through epigenetic modifications to regulate coronary artery disease gene expression (2019) (0)
Transcription factor regulation as a mechanism of confounding effects between distinct human traits (2015) (0)
Abstract 386: Identification of Genetic Regulatory Networks for Insulin Resistance in Multiple Populations of Diverse Ethnicities (2017) (0)
Rapid Lifestyle Prototyping: Assessment of Infrared Spectroscopic Blood Responses for Short-term Lifestyle Interventions (2021) (0)
Abstract 955: Apelin Reverses Pathologic Ventricular Remodeling in the db/db Obese Mouse (2006) (0)
Abstract 5556: Apelin Regulates Vascular Remodeling In The Mouse Carotid Artery Ligation Model (2008) (0)
EXPRESSION OF A RECOMBINANT ANTIBODY-TARGETED THROMBOLYTIC MOLECULE (1987) (0)
Molecular mechanisms of coronary artery disease risk at the PDGFD locus (2023) (0)
Abstract 341: Both Beta-1 and Beta-2 Adrenergic Receptors (ARs) are Required for Pressure Overload Cardiac Hypertrophy (2007) (0)
Molecular mechanisms of coronary artery disease risk at the PDGFD locus (2022) (0)
Abstract 319: Electronic Cigarettes Activate The Heat Shock Response In Vascular Smooth Muscle In Atherosclerosis (2022) (0)
Genomic Assessment of Cardiac Transplant Rejection (2010) (0)
Abstract 17784: The Genesips Project: an NHLBI-Sponsored induced Pluripotent Stem Cell (iPSC) Resource for the Study of Cardiovascular Diseases (2014) (0)
Integration of Coronary Artery Disease Genome-wide Association Studies with Bulk and Single-cell Transcriptomics from Atherosclerotic Plaques by Deconvolution, Reveals Novel Smooth Muscle Cell Genes Single-cell and Spatially Resolved Transcriptome Analysis Reveals Cellular Heterogeneities and Novel (2022) (0)
enhances directed cardiac differentiation of mouse and human embryonic stem cells. (2012) (0)
Genome-wide copy number variation analysis identified deletions in SFMBT1 associated with fasting plasma glucose in a Han Chinese population (2017) (0)
OJ-064 Identification of non-secreted endothelial cell-derived lipase (EDL) isoforms in human endothelial cells(Lipid Disorders 1 (H) : OJ8)(Oral Presentation (Japanese)) (2004) (0)
Abstract 18374: TCF21 and Aryl-Hydrocarbon Receptor Gene Cooperate to Activate a Pro-Atherosclerotic Gene Expression Program (2016) (0)
Tu-P7:178 Inflammation is the primary signature of gene expression profile in leukocytes of insulin-resistant subjects (2006) (0)
Abstract 360: Epigenomic Changes Govern Smooth Muscle Cell Phenotype Shift In Marfan Syndrome Aortic Root Aneurysm (2022) (0)
The role of developmental endothelial locus 1 (Del1) in skeletal development (2004) (0)
The role of insulin as a key regulator of seeding, proliferation, and mRNA transcription of human pluripotent stem cells (2019) (0)
Abstract 17096: CDKN2B Regulates Cell Fate Decisions in Human Vascular Smooth Muscle Cells (2010) (0)
Supplementary Material (nature09270-s1) (2012) (0)
Abstract MP57: Pathway and Network Analysis of GWAS reveals Novel Candidate Causal Links between Key Biological Processes and Coronary Artery Disease (2014) (0)
CHAPTER 60 – Application of Genomic Methodology for Assessment of Cardiac Transplant Rejection (2009) (0)
Abstract 141: Coronary Heart Disease-Associated Variation in TCF21 Disrupts a MicroRNA-224 Binding Site and miRNA-Mediated Regulation (2014) (0)
LncRNA de novo discovery reveals noncoding RNAs as major molecular mechanism associating coronary artery disease GWAS variants with causal genes to confer disease risk (2019) (0)
Recruitment Adhesion Inhibitor , Limits Inflammatory Cell Del-1 , an Endogenous Leukocyte-Endothelial (2009) (0)
Abstract 664: The Coronary Heart Disease--Associated Transcription Factor TCF21 Regulates Disease-Related Genes and May Contribute to the Migration of SMC Progenitors to the Fibrous Cap (2014) (0)
Erratum to: Genetic variation in the carbonyl reductase 3 gene confers risk of type 2 diabetes and insulin resistance: a potential regulator of adipogenesis (2012) (0)
988-7 Endothelin ETA/B Receptor Antagonist Reduces Infarct Size: A Novel Therapy for Acute Myocardial Infarction (1995) (0)
Abstract 10952: Network Analysis Identifies the Orphan Receptor Tyrosine Kinase Ros1 as a Determinant of Glutathione Peroxidase-1 Mediated Vascular Remodeling (2011) (0)
Integration of CAD-associated GWAS loci and deconvolution from human carotid plaques to study smooth muscle cell function in atherosclerosis (2022) (0)
988-7 Endothelin ETA/B Receptor Antagonist Reduces Infarct Size: A Novel Therapy for Acute Myocardial Infarction (1995) (0)
IS023 FUNCTIONAL IDENTIFICATION OF THE MOUSE ENDOTHELIN-1 GENE ENHANCER REGION IN ENDOTHELIAL CELLS (1997) (0)
W10-O-001 Endothelial lipase deficiency increases plasma cholesterol but reduces susceptibility to atherosclerosis in apolipoprotein E-deficient mice (2005) (0)
Development of a novel platform device for reliable and reproducible rodent echocardiography (2006) (0)
Molecular basis of regulatory variation at coronary heart disease associated loci (2015) (0)
Abstract 619: Regulatory Mechanism of Lmod1 Mediated Predisposition to Coronary Artery Disease (2018) (0)
4P-1101 Role of endothelial cell-derived lipase in endotoxemia (2003) (0)
Abstract 463: Hypoxia is a Primary Stimulus for Up-Regulation of the Apelin-APJ Cardio-Regulatory Pathway (2006) (0)
Genome-Wide Association Studies For Coronary Artery Disease Risk (2018) (0)
Abstract 14977: Impact of Type 2 Diabetes Susceptibility Loci on Variation in Physiologic Glycaemic Traits in Non-Diabetic Individuals (2012) (0)
TCF21 regulates basic cellular functions in vascular smooth muscle cells in vitro. (2015) (0)
GENETIC DETERMINANTS OF DRAMATIC IMPROVEMENT IN LEFT VENTRICULAR FUNCTION IN PATIENTS WITH HEART FAILURE (2011) (0)
CRP-level-associated polymorphism rs1205 within the CRP gene is associated with 2-hour glucose level: The SAPPHIRe study (2017) (0)
Abstract 2368: Long-term Apelin Infusion Rescues Chronic Cardiomyopathy and Potentiates the Effects of ACE-Inhibition (2006) (0)
Molecular Biology Applications in Cardiovascular Medicine (2005) (0)
Abstract 1433: The Cardioregulatory Peptide Apelin is Preferentially Expressed by Endothelial Cells and Upregulated in Myocardial Disease States (2007) (0)
Genetic variation of SORBS1 gene is associated with glucose homeostasis and age at onset of diabetes: A SAPPHIRe Cohort Study (2018) (0)
Opportunities and challenges for transcriptome-wide association studies (2019) (0)
Molecular Biology of Vascular Remodeling (2002) (0)
Erratum to: Genetic variation in the carbonyl reductase 3 gene confers risk of type 2 diabetes and insulin resistance: a potential regulator of adipogenesis (2012) (0)
Trans-ethnic fine-mapping of genetic loci for body mass index in the diverse ancestral populations of the Population Architecture using Genomics and Epidemiology (PAGE) Study reveals evidence for multiple signals at established loci (2017) (0)
Book Review Molecular Cardiovascular Medicine (Scientific American Introduction to Molecular Medicine.) Edited by Edgar Haber. 338 pp., illustrated. New York, Scientific American, 1995. $49. 0-89454-021-1 (1996) (0)
Abstract 5683: Insights From Network Analysis: Deficiency of Glutathione Peroxidase-1 Increases In-stent Stenosis (2009) (0)
EVALUATION DU NIVEAU D'EXPRESSION LEUCOCYTAIRE (2001) (0)
Abstract 14363: Genetics of Coronary Atherosclerotic Plaque Rupture and Myocardial Infarction (2010) (0)
Discovery of Transacting Long Noncoding RNAs That Regulate Smooth Muscle Cell Phenotype (2023) (0)
Abstract 3612: Apelin Prevents Aortic Aneurysm Formation by Inhibiting Macrophage Inflammation and Infiltration (2008) (0)
Abstract 1216: The Cardioactive Peptide Apelin Increases Adipocyte Glucose Uptake and is Necessary for the Maintenance of Systemic Insulin Sensitivity (2007) (0)
Genetic variation in the carbonyl reductase 3 gene confers risk of type 2 diabetes and insulin resistance: a potential regulator of adipogenesis (2012) (0)
Abstract 3756: Atherosclerosis Development is Increased in Apelin/Apoe Double Knockout Mice (2008) (0)
Abstract 2059: Apelin Potently Inhibits Angiotensin and Disease Induced Superoxide Generation and Associated Vascular Remodeling in Vein Grafts (2007) (0)
The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits. (2023) (0)
Single nuclei multiomic analyses identify human cardiac lymphatic endothelial cells associated with coronary arteries in the epicardium (2023) (0)
Abstract 5651: Apelin Deficient Mice Demonstrate Worsening Pulmonary Hypertension in a Nitric Oxide Dependent Manner (2009) (0)
Abstract 544: Single-Cell RNA Sequencing Suggests Roles For Cell-Matrix Interactions And Inflammation In The Pathogenesis Of Aortopathy In Loeys-Dietz Syndrome (2022) (0)
Abstract 1475: The Apelin-APJ Pathway Is an Endogenous Regulator of Cardiac Function and Is Upregulated in Cardiac Pressure Overload (2008) (0)
Abstract P3006: A Human Arterial Cell Atlas (2022) (0)
Abstract 16018: Genetic variation near HCRTR2 associates with dramatic improvement of heart function in patients with heart failure (2013) (0)
Production of a Genomic DNA Library (1991) (0)
Abstract 12075: Whole-Genome Sequencing at 10-Days of Life in Perinatal Long-QT Syndrome Yields New Insights Into Disease Pathogenesis (2014) (0)
P4918PCSK6 is a key protease in the control of smooth muscle cell function in vascular remodelling (2017) (0)
A COMPARISON OF PSYCHOLOGICAL DISTRESS SCREENING TOOLS FROM A CROSS-SECTIONAL SURVEY OF WOMEN AT TWO ANTENATAL CLINICS IN CHITUNGWIZA , ZIMBABWE (2010) (0)
Abstract 14473: Apelin Inhibits Lipolysis in a Gq-, Gi-, and AMPK-Dependent Manner (2010) (0)
Nitric oxide-cyclic GMP regulates transcription of the endothelin-1 gene (1994) (0)
Abstract 250: In vivo Kinetics of Embryonic Stem Cell Viability Following Transplantation Into the Injured Murine Myocardium (2009) (0)
Abstract 107: A Human Arterial Cell Atlas (2022) (0)
Abstract 532: Dioxin Modifies The Transcriptomic And Epigenetic Landscape Of Smooth Muscle Cells Leading To Adverse Remodeling Of Atherosclerosis (2022) (0)
Abstract 113: Cell-specific Chromatin Landscape Of Human Coronary Artery Resolves Mechanisms Of Disease Risk (2021) (0)
Abstract 3129: Molecular and Physiologic Characterization of RV Remodeling and Failure in a Murine Model of Mild, Moderate and Severe Pulmonary Stenosis (2007) (0)
Increased rate of hair regrowth in mice with constitutive over expression of the angiogenic factor Del1 in basal keratinocytes (2004) (0)
database mining and microarray analysis Identification of endothelial cell genes by combined (2015) (0)
Author Correction: Single-nucleus chromatin accessibility profiling highlights regulatory mechanisms of coronary artery disease risk (2022) (0)
Abstract 706: The Apelin Receptor APJ Directly Inhibits Angiotensin II Signaling by Binding to Angiotensin II Receptor Type I and is Essential for Cardiac Development and Function (2006) (0)
Lipid loci with multiple signals in Europeans. (2013) (0)
Abstract 10916: Mendelian Randomization Studies Do Not Support a Causal Effect of Plasma Lipids on Insulin Sensitivity (2012) (0)
Abstract 18949: The Role of CDKN2B in Vascular Disease (2010) (0)
20: The Resuscitated DCD Donor Heart Is Functionally Superior to the Brainstem Dead Donor Heart (2009) (0)
701 Protective Activity of Apelin On Experimentally-Induced Colitis (2009) (0)
Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene - eScholarship (2015) (0)
Targeted Disruption and Overexpression of Endothelial Cell-Derived Lipase Modulates Plasma HDL and LDL Cholesterol Levels (2003) (0)
Abstract 21021: Functional Regulatory Mechanism of Smooth Muscle Cell-Restricted LMOD1 Coronary Artery Disease Locus (2017) (0)
Abstract 402: Adiponectin Receptor 3 is Associated With Endothelial Nitric Oxide Synthase Dysfunction and Predicts Insulin Resistance in South Asians (2019) (0)
The epigenomic landscape of single vascular cells reflects developmental origin and identifies disease risk loci (2022) (0)
404-1 In vivo magnetic resonance evaluation of the effects of mouse embryonic stem cells on cardiac function (2004) (0)
NAT1 KNOCKDOWN RESULTS IN AN INSULIN RESISTANCE PHENOTYPE IN VITRO AND IN VIVO (2015) (0)
proliferation in patients with T cell lymphocytosis and cytopenia T cell receptor gene rearrangements define a monoclonal T cell (2011) (0)

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