Thomas Thornton Macdonald

Thomas Thornton Macdonald's AcademicInfluence.com Rankings

Medical

#1450

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#1789

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Gastroenterology

#20

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#20

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medical Degrees

Thomas Thornton Macdonald

Biology

#5993

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#8606

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Immunology

#302

World Rank

#313

Historical Rank

biology Degrees

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Biology

Thomas Thornton Macdonald's Degrees

PhD Immunology Stanford University
Doctorate Medicine Stanford University

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Thomas Thornton Macdonald's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Immunity, Inflammation, and Allergy in the Gut (2005) (1051)
Tumour necrosis factor alpha in stool as a marker of intestinal inflammation (1992) (719)
Blocking Smad7 restores TGF-beta1 signaling in chronic inflammatory bowel disease. (2001) (577)
Location of tumour necrosis factor alpha by immunohistochemistry in chronic inflammatory bowel disease. (1993) (542)
Tumor necrosis factor α-producing cells in the intestinal mucosa of children with inflammatory bowel disease (1994) (518)
Tumour necrosis factor‐alpha and interferon‐gamma production measured at the single cell level in normal and inflamed human intestine (1990) (488)
Citrobacter rodentium of mice and man (2005) (487)
Serum concentrations of tumour necrosis factor alpha in childhood chronic inflammatory bowel disease. (1991) (475)
Curcumin as a therapeutic agent: the evidence from in vitro, animal and human studies (2010) (441)
Aryl hydrocarbon receptor-induced signals up-regulate IL-22 production and inhibit inflammation in the gastrointestinal tract. (2011) (441)
Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells (2005) (427)
Evidence that activated mucosal T cells play a role in the pathogenesis of enteropathy in human small intestine (1988) (402)
Th17-type cytokines, IL-6 and TNF-α synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth (2014) (387)
Characterisation of Acute Murine Dextran Sodium Sulphate Colitis: Cytokine Profile and Dose Dependency (2000) (379)
A major role for matrix metalloproteinases in T cell injury in the gut. (1997) (350)
Homeostasis of the gut barrier and potential biomarkers (2016) (341)
Interleukin-2- and interferon-gamma-secreting T cells in normal and diseased human intestinal mucosa. (1993) (322)
Citrobacter rodentium Infection in Mice Elicits a Mucosal Th1 Cytokine Response and Lesions Similar to Those in Murine Inflammatory Bowel Disease (1999) (306)
The Transcription Factor T-bet Regulates Intestinal Inflammation Mediated by Interleukin-7 Receptor+ Innate Lymphoid Cells (2012) (300)
Interleukin-21 enhances T-helper cell type I signaling and interferon-gamma production in Crohn's disease. (2005) (297)
Differential regulation of interleukin 17 and interferon γ production in inflammatory bowel disease (2009) (291)
IL-21 Counteracts the Regulatory T Cell-Mediated Suppression of Human CD4+ T Lymphocytes1 (2007) (288)
Interferon gamma and interleukin 4 secreting cells in the gastric antrum in Helicobacter pylori positive and negative gastritis. (1995) (282)
Can probiotics modulate human disease by impacting intestinal barrier function? (2017) (281)
Inflammatory skin and bowel disease linked to ADAM17 deletion. (2011) (277)
Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases. (2017) (264)
Regulation of gut inflammation and th17 cell response by interleukin-21. (2008) (258)
IL‐23/IL‐17 axis in IBD (2010) (250)
Regulation of homeostasis and inflammation in the intestine. (2011) (248)
The mucosal immune system (2003) (245)
Expression of disulfide‐linked and non‐disulfide‐linked forms of the T cell receptor γ/δ heterodimer in human intestinal intraepithelial lymphocytes (1989) (231)
Tumor necrosis factor alpha-producing cells in the intestinal mucosa of children with inflammatory bowel disease. (1994) (217)
Expression of lymphocyte-endothelial receptor-ligand pairs, α4β7/MAdCAM-1 and OX40/OX40 ligand in the colon and jejunum of patients with inflammatory bowel disease (1999) (211)
Involvement of interleukin-21 in the epidermal hyperplasia of psoriasis (2009) (203)
IL‐21 regulates experimental colitis by modulating the balance between Treg and Th17 cells (2007) (192)
Impaired Resistance and Enhanced Pathology During Infection with a Noninvasive, Attaching-Effacing Enteric Bacterial Pathogen, Citrobacter rodentium, in Mice Lacking IL-12 or IFN-γ (2002) (190)
Transforming growth factor β signalling and matrix metalloproteinases in the mucosa overlying Crohn’s disease strictures (2009) (188)
Central Role for B Lymphocytes and CD4+ T Cells in Immunity to Infection by the Attaching and Effacing Pathogen Citrobacter rodentium (2003) (186)
Inhibition of Smad7 with a specific antisense oligonucleotide facilitates TGF-beta1-mediated suppression of colitis. (2006) (186)
Regulation of T cell activation in vitro and in vivo by targeting the OX40-OX40 ligand interaction: amelioration of ongoing inflammatory bowel disease with an OX40-IgG fusion protein, but not with an OX40 ligand-IgG fusion protein. (1999) (185)
The development of gut associated lymphoid tissue in the terminal ileum of fetal human intestine. (1986) (175)
Changes in intraepithelial lymphocyte subpopulations in coeliac disease and enteropathy associated T cell lymphoma (malignant histiocytosis of the intestine). (1989) (172)
Interleukin 21 contributes to the mucosal T helper cell type 1 response in coeliac disease (2007) (171)
Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression. (2009) (166)
IL‐23‐mediated regulation of IL‐17 production in Helicobacter pylori‐infected gastric mucosa (2008) (165)
IL‐4‐regulated enteropathy in an intestinal nematode infection (1998) (163)
Disruption of sulphated glycosaminoglycans in intestinal inflammation (1993) (162)
Role of bacterial intimin in colonic hyperplasia and inflammation. (1999) (160)
Imbalance of stromelysin-1 and TIMP-1 in the mucosal lesions of children with inflammatory bowel disease (2000) (158)
A functional role for interleukin-21 in promoting the synthesis of the T-cell chemoattractant, MIP-3alpha, by gut epithelial cells. (2007) (154)
Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease (2015) (153)
Differential expression of CD25 (interleukin-2 receptor) on lamina propria T cells and macrophages in the intestinal lesions in Crohn's disease and ulcerative colitis. (1990) (153)
A Failure of Transforming Growth Factor-β1 Negative Regulation Maintains Sustained NF-κB Activation in Gut Inflammation* (2004) (150)
Cell-mediated immunity to intestinal infection (1980) (148)
Functional modulation of Crohn's disease myofibroblasts by anti-tumor necrosis factor antibodies. (2007) (148)
Interleukin 18 and associated markers of T helper cell type 1 activity in coeliac disease (2002) (147)
High endothelin-1 immunoreactivity in Crohn's disease and ulcerative colitis (1992) (146)
Role of interferon α in promoting T helper cell type 1 responses in the small intestine in coeliac disease (2001) (140)
A p55 TNF receptor immunoadhesin prevents T cell-mediated intestinal injury by inhibiting matrix metalloproteinase production. (1998) (136)
DIFFERENTIAL REGULATION OF INTERLEUKIN-17 AND INTERFERON-GAMMA PRODUCTION IN INFLAMMATORY BOWEL DISEASE (2009) (134)
Smad7 in TGF-β-mediated negative regulation of gut inflammation (2004) (132)
Involvement of interleukin-21 in the regulation of colitis-associated colon cancer (2011) (131)
A regenerative role for bone marrow following experimental colitis: contribution to neovasculogenesis and myofibroblasts. (2005) (131)
Interleukin-25 inhibits interleukin-12 production and Th1 cell-driven inflammation in the gut. (2009) (128)
T cells orchestrate intestinal mucosal shape and integrity. (1999) (122)
In Vivo Bioluminescence Imaging of the Murine Pathogen Citrobacter rodentium (2006) (119)
Cytokines in stools of children with inflammatory bowel disease or infective diarrhoea. (1993) (119)
Immune mechanisms in chronic inflammatory bowel disease. (1994) (118)
Critical Role for Tumor Necrosis Factor Alpha in Controlling the Number of Lumenal Pathogenic Bacteria and Immunopathology in Infectious Colitis (2001) (115)
Evidence for the role of interferon-alfa production by dendritic cells in the Th1 response in celiac disease. (2007) (114)
Neutrophils in ulcerative colitis: a review of selected biomarkers and their potential therapeutic implications (2017) (110)
The IL-33/ST2 axis: Role in health and disease. (2015) (110)
Characterization of IL-17A–Producing Cells in Celiac Disease Mucosa (2010) (110)
Curcumin suppresses p38 mitogen-activated protein kinase activation, reduces IL-1β and matrix metalloproteinase-3 and enhances IL-10 in the mucosa of children and adults with inflammatory bowel disease (2009) (109)
CELL-MEDIATED IMMUNITY TO GLIADIN WITHIN THE SMALL-INTESTINAL MUCOSA IN CŒLIAC DISEASE (1975) (109)
American Journal of Physiology: Gastrointestinal and Liver Physiology American Journal of Physiology: Heart and Circulatory Physi- QlQgY American Journal of Physiology: Regulatory, Integrative and Comparative Physiology American Journal of Physiology: Renal, Fluid and Electrolyte (2003) (108)
Autocrine Regulation of IL-21 Production in Human T Lymphocytes1 (2008) (108)
Collagenase-1 (MMP-1), matrilysin-1 (MMP-7), and stromelysin-2 (MMP-10) are expressed by migrating enterocytes during intestinal wound healing (2004) (107)
Changes in the rate of crypt epithelial cell proliferation and mucosal morphology induced by a T-cell-mediated response in human small intestine. (1990) (105)
TGF-β1 and Smad7 in the regulation of IBD (2008) (105)
Upregulation of matrix metalloproteinases in a model of T cell mediated tissue injury in the gut: analysis by gene array and in situ hybridisation (2002) (104)
Extrathymic T cell differentiation in the human intestine early in life. (1998) (101)
Regulation of the T helper cell type 1 transcription factor T-bet in coeliac disease mucosa (2004) (101)
Polymeric nutrition as the primary therapy in children with small bowel Crohn's disease. (1994) (101)
Targeting Gut T Cell Ca2+ Release-Activated Ca2+ Channels Inhibits T Cell Cytokine Production and T-Box Transcription Factor T-Bet in Inflammatory Bowel Disease (2009) (99)
Post-transcriptional regulation of Smad7 in the gut of patients with inflammatory bowel disease. (2005) (99)
Interleukin-21: a critical regulator of the balance between effector and regulatory T-cell responses. (2008) (99)
Enhancing Lamina propria Th1 cell responses with interleukin 12 produces severe tissue injury. (1999) (99)
Suppression of T cell-mediated injury in human gut by interleukin 10: role of matrix metalloproteinases. (1998) (98)
IL-21 Is Highly Produced in Helicobacter pylori-Infected Gastric Mucosa and Promotes Gelatinases Synthesis1 (2007) (98)
Intestinal nematode infections in children: the pathophysiological price paid (1992) (96)
T-cell activation can induce either mucosal destruction or adaptation in cultured human fetal small intestine. (1993) (96)
Growth suppression in the Trichuris dysentery syndrome. (1990) (95)
The Frequency of Cells Secreting Interferon-γ and Interleukin-4, -5, and -10 in the Blood and Duodenal Mucosa of Children with Cow's Milk Hypersensitivity (1997) (93)
Psoriasis: from pathogenesis to novel therapeutic approaches. (2011) (93)
Keratinocyte growth factor in inflammatory bowel disease. Increased mRNA transcripts in ulcerative colitis compared with Crohn's disease in biopsies and isolated mucosal myofibroblasts. (1997) (93)
Human Peyer’s Patch T Cells Are Sensitized to Dietary Antigen and Display a Th Cell Type 1 Cytokine Profile1 (2000) (92)
Effector and regulatory lymphoid cells and cytokines in mucosal sites. (1999) (91)
A rapid diagnostic test for human regulatory T-cell function to enable regulatory T-cell therapy. (2012) (90)
Interferon‐gamma‐expressing cells are a major source of interleukin‐21 in inflammatory bowel diseases (2010) (90)
Inhibition of NF-κB Signaling in Human Dendritic Cells by the Enteropathogenic Escherichia coli Effector Protein NleE (2010) (90)
Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2 (2020) (89)
Proteolytic cleavage and loss of function of biologic agents that neutralize tumor necrosis factor in the mucosa of patients with inflammatory bowel disease. (2015) (88)
IL-12 and Th1 immune responses in human Peyer's patches. (2001) (86)
Matrix metalloproteinases and the gut - new roles for old enzymes. (2004) (86)
Interactions between stromal cell--derived keratinocyte growth factor and epithelial transforming growth factor in immune-mediated crypt cell hyperplasia. (1998) (84)
The endogenous cannabinoid system in the gut of patients with inflammatory bowel disease (2011) (84)
Gamma/delta T cells in the gut epithelium. (1990) (84)
Role of IL-15 in immune-mediated and infectious diseases. (2011) (84)
Blockade of transforming growth factor β upregulates T-box transcription factor T-bet, and increases T helper cell type 1 cytokine and matrix metalloproteinase-3 production in the human gut mucosa (2008) (83)
The role of transforming growth factor (TGF)-β in modulating the immune response and fibrogenesis in the gut. (2014) (81)
T cell subclasses in fetal human ileum. (1986) (80)
In Crohn's disease fibrosis-reduced expression of the miR-29 family enhances collagen expression in intestinal fibroblasts. (2014) (80)
Decreased mucosal interleukin-4 (IL-4) production in gut inflammation. (1994) (80)
Myofibroblast matrix metalloproteinases activate the neutrophil chemoattractant CXCL7 from intestinal epithelial cells. (2006) (80)
A role for gut-associated lymphoid tissue in shaping the human B cell repertoire (2013) (79)
Breakdown of tolerance to the intestinal bacterial flora in inflammatory bowel disease (IBD) (1995) (79)
The aryl hydrocarbon receptor in inflammatory bowel disease: linking the environment to disease pathogenesis (2012) (79)
The Identification and Pharmacological Characterization of 6-(tert-Butylsulfonyl)-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine (GSK583), a Highly Potent and Selective Inhibitor of RIP2 Kinase. (2016) (78)
Characterization of the mucosal cell‐mediated immune response in IL‐2 knockout mice before and after the onset of colitis (1997) (78)
New Pathogenic Paradigms in Inflammatory Bowel Disease (2012) (77)
The unusual suspects—innate lymphoid cells as novel therapeutic targets in IBD (2015) (76)
Interferon‐α drives T cell‐mediated immunopathology in the intestine (2001) (76)
Small intestinal epithelial cell kinetics and protozoal infection in mice. (1978) (75)
Tumour necrosis factor in the bronchoalveolar secretions of infants with the respiratory distress syndrome and the effect of dexamethasone treatment. (1992) (75)
New players in the cytokine orchestra of inflammatory bowel disease (2007) (75)
Interleukin-21 as a new therapeutic target for immune-mediated diseases. (2009) (74)
Cytotoxic α/β+ and γ/δ+ T cells in murine intestinal epithelium (1990) (72)
The role of interleukin 17 in Crohn’s disease-associated intestinal fibrosis (2013) (71)
Bacterial regulation of intestinal immune responses. (2005) (71)
The Food Additive Maltodextrin Promotes Endoplasmic Reticulum Stress–Driven Mucus Depletion and Exacerbates Intestinal Inflammation (2018) (71)
Impaired Immunity to Intestinal Bacterial Infection in Stromelysin-1 (Matrix Metalloproteinase-3)-Deficient Mice1 (2004) (71)
Protease-activated receptor-2 activation in gastric cancer cells promotes epidermal growth factor receptor trans-activation and proliferation. (2006) (71)
Induction and regulation of Smad7 in the gastric mucosa of patients with Helicobacter pylori infection. (2004) (70)
Absence of a role for interleukin‐13 in inflammatory bowel disease (2014) (70)
Hypersensitivity reactions in the small intestine. 2. Effects of allograft rejection on mucosal architecture and lymphoid cell infiltrate. (1976) (69)
Smad7 in TGF-beta-mediated negative regulation of gut inflammation. (2004) (69)
Requirement for a bacterial flora before mice generate cells capable of mediating the delayed hypersensitivity reaction to sheep red blood cells. (1979) (69)
Interleukin 6 Increases Production of Cytokines by Colonic Innate Lymphoid Cells in Mice and Patients With Chronic Intestinal Inflammation (2015) (68)
The role of matrix metalloproteinases in stromal/epithelial interactions in the gut. (2007) (68)
Interleukin-21 (IL-21)-mediated pathways in T cell-mediated disease. (2009) (67)
T-cell receptor expression in intestinal intra-epithelial lymphocyte subpopulations of normal and athymic mice. (1989) (66)
Up-Regulation of Collagen and Tissue Inhibitors of Matrix Metalloproteinase in Colonic Diverticular Disease (2004) (66)
Proteases and the gut barrier (2013) (66)
Inhibition of monocyte-derived inflammatory cytokines by IL-25 occurs via p38 Map kinase-dependent induction of Socs-3. (2009) (65)
Yersinia enterocolitica infection in resistant and susceptible strains of mice (1986) (65)
Cancer immunoediting and "spontaneous" tumor regression. (2010) (65)
Defective expression of SIRT1 contributes to sustain inflammatory pathways in the gut (2014) (64)
Cryptogenic multifocal ulcerating stenosing enteritis associated with homozygous deletion mutations in cytosolic phospholipase A2-α (2012) (64)
Smad7 expression in T cells prevents colitis-associated cancer. (2011) (64)
The role of activated T lymphocytes in gastrointestinal disease (1990) (64)
Aetiology and pathogenesis of chronic inflammatory bowel disease. (1994) (63)
T cell immunity to oral allergens. (1998) (62)
Immediate hypersensitivity in colon of children with chronic Trichuris trichiura dysentery (1991) (62)
Immunosuppression caused by antigen feeding II. Suppressor T cells mask Peyer's patch B cell priming to orally administered antigen (1983) (61)
Interleukin-22 orchestrates a pathological endoplasmic reticulum stress response transcriptional programme in colonic epithelial cells (2019) (61)
Cytokine & Growth Factor Reviews (2015) (61)
Gastrointestinal Inflammation: Inflammatory bowel disease in knockout mice (1994) (60)
High frequency of CD8αα homodimer‐bearing T cells in human fetal intestine (1994) (60)
Costimulatory molecules in the developing human gastrointestinal tract: a pathway for fetal allergen priming. (2001) (60)
A functional role for Smad7 in sustaining colon cancer cell growth and survival (2014) (60)
Matrix Metalloproteinases in Necrotising Enterocolitis (2003) (60)
Emerging immunological targets in inflammatory bowel disease. (2011) (60)
Plasma Cells in the Mucosa of Patients with Inflammatory Bowel Disease Produce Granzyme B and Possess Cytotoxic Activities (2014) (59)
Butyrate upregulates stromelysin-1 production by intestinal mesenchymal cells. (2000) (57)
Heterogeneity in Intraepithelial Lymphocyte Subpopulations in Fetal and Postnatal Human Small Intestine (1989) (55)
Immunoepidemiology of intestinal helminthic infections. 3. Mucosal macrophages and cytokine production in the colon of children with Trichuris trichiura dysentery. (1994) (53)
HLA-DR expression in human fetal intestinal epithelium. (1988) (53)
Microbial-gut interactions in health and disease. Immune responses. (2004) (53)
Proteolytic degradation of intestinal mucosal extracellular matrix after lamina propria T cell activation. (1996) (53)
IL-7 receptor influences anti-TNF responsiveness and T cell gut homing in inflammatory bowel disease. (2019) (52)
Functional properties of lymphocytes isolated from murine small intestinal epithelium. (1984) (52)
Technique for microdissection and measurement in biopsies of human small intestine. (1977) (52)
Role of NleH, a Type III Secreted Effector from Attaching and Effacing Pathogens, in Colonization of the Bovine, Ovine, and Murine Gut (2008) (52)
Down‐regulation of p38 mitogen‐activated protein kinase activation and proinflammatory cytokine production by mitogen‐activated protein kinase inhibitors in inflammatory bowel disease (2010) (51)
Matrix metalloproteinases and their inhibitors in the nasal mucosa of patients with perennial allergic rhinitis. (2001) (51)
Expression of disulfide-linked and non-disulfide-linked forms of the T cell receptor gamma/delta heterodimer in human intestinal intraepithelial lymphocytes. (1989) (50)
Matrix metalloproteinase‐3 production by gut IgG plasma cells in chronic inflammatory bowel disease (2008) (50)
Heterogeneity of non-lymphoid cells expressing HLA-D region antigens in human fetal gut. (1987) (50)
Host defences to Citrobacter rodentium. (2003) (50)
IL‐25 prevents and cures fulminant hepatitis in mice through a myeloid‐derived suppressor cell‐dependent mechanism (2013) (48)
Stimulation of mucosal T cells in situ with anti-CD3 antibody: location of the activated T cells and their distribution within the mucosal micro-environment. (1988) (48)
Histopathology and immunohistochemistry of the caecum in children with the Trichuris dysentery syndrome. (1991) (47)
Constitutive activation of the signal transducer and activator of transcription pathway in celiac disease lesions. (2003) (47)
Manipulation of cytokines in the management of patients with inflammatory bowel disease (2000) (46)
Selective death of T cell receptor γ/δ+ intraepithelial lymphocytes by apoptosis (1990) (46)
Parallel expression of macrophage metalloelastase (MMP-12) in duodenal and skin lesions of patients with dermatitis herpetiformis (2001) (45)
Cell-mediated immunity to gliadin within the small-intestinal mucosa in coeliac disease. (1975) (45)
Interleukin-25: a two-edged sword in the control of immune-inflammatory responses. (2010) (45)
Activated eosinophils in chronic inflammatory bowel disease (1990) (44)
Cyclosporin as initial treatment for Crohn's disease. (1994) (44)
Keratinocyte growth factor and coeliac disease (2001) (44)
Peripheral regulatory T cells and serum transforming growth factor‐&bgr;: Relationship with clinical response to infliximab in Crohn's disease (2010) (44)
Interleukin-21 sustains inflammatory signals that contribute to sporadic colon tumorigenesis (2015) (43)
35 – Gut-Associated Lymphoid Tissue (1994) (43)
Direct in vitro infection of human intestine with HIV‐1 (1992) (43)
Effects of local delayed hypersensitivity on the small intestine. (1977) (42)
Isolation and functional characteristics of adherent phagocytic cells from mouse Peyer's patches. (1982) (42)
Systemic administration of the chemokine macrophage inflammatory protein 1α exacerbates inflammatory bowel disease in a mouse model (2005) (42)
IL-21 Promotes Skin Recruitment of CD4+ Cells and Drives IFN-γ–Dependent Epidermal Hyperplasia (2011) (41)
Preclinical Development of a Novel, Orally-Administered Anti-Tumour Necrosis Factor Domain Antibody for the Treatment of Inflammatory Bowel Disease (2018) (40)
Interleukin-25 production is differently regulated by TNF-α and TGF-β1 in the human gut (2011) (40)
Probiotics and the immune response to vaccines (2010) (40)
Childhood Crohn's disease and the efficacy of enteral diets. (1998) (40)
The p50 Subunit of NF-κB Is Critical for In Vivo Clearance of the Noninvasive Enteric Pathogen Citrobacter rodentium (2008) (40)
The pathophysiologic rationale for biological therapies in inflammatory bowel disease (2005) (39)
Proteases and small intestinal barrier function in health and disease (2014) (39)
Recent advances in understanding ulcerative colitis (2012) (39)
Regional variation in the proliferative rate and lifespan of alpha beta TCR+ and gamma delta TCR+ intraepithelial lymphocytes in the murine small intestine. (1995) (39)
Passive protection of chickens against Eimeria tenella infection by monoclonal antibody (1988) (38)
Proinflammatory Vδ2+ T Cells Populate the Human Intestinal Mucosa and Enhance IFN-γ Production by Colonic αβ T Cells (2013) (38)
Lymphokine production by mitogen and antigen activated mouse intraepithelial lymphocytes. (1986) (38)
Activation of lamina propria T cells induces crypt epithelial proliferation and goblet cell depletion in cultured human fetal colon. (1992) (38)
Role of Macrophage Metalloelastase in Gut Inflammation (2006) (38)
Selective biopsy of human Peyer's patches during ileal endoscopy. (1987) (38)
The distribution of dividing T cells throughout the intestinal wall in inflammatory bowel disease (IBD) (1996) (37)
Smad7 induces plasticity in tumor-infiltrating Th17 cells and enables TNF-alpha-mediated killing of colorectal cancer cells. (2014) (37)
Lamina propria T cells. (1998) (37)
Mechanisms of tissue injury (2004) (36)
Bacterial regulation of intestinal immune responses. (2000) (36)
Ontogeny of the Immune System of the Gut (1990) (36)
Immunosuppression caused by antigen feeding. I. Evidence for the activation of a feedback suppressor pathway in the spleens of antigen‐fed mice (1982) (36)
Ligation of alpha4ss1 integrin on human intestinal mucosal mesenchymal cells selectively Up-regulates membrane type-1 matrix metalloproteinase and confers a migratory phenotype. (2000) (36)
Analysis of TH1 and TH2 cytokine production in low grade B cell gastric MALT-type lymphomas stimulated in vitro with Helicobacter pylori. (1997) (34)
Increased expression of laminin/collagen receptor (VLA-1) on epithelium of inflamed human intestine. (1990) (34)
Tissue inhibitor of metalloproteinase-3 regulates inflammation in human and mouse intestine. (2012) (34)
IL-21 comes of age as a regulator of effector T cells in the gut (2008) (33)
Analysis of the cytokine profile in the duodenal mucosa of refractory coeliac disease patients. (2014) (33)
Expression of Intimin γ from EnterohemorrhagicEscherichia coli in Citrobacter rodentium (2000) (33)
Induction and modulation of gastrointestinal inflammation. (1998) (32)
What's the next best cytokine target in IBD? (2012) (32)
An analysis of interferon gamma, IL-4, IL-5 and IL-10 production by ELISPOT and quantitative reverse transcriptase-PCR in human Peyer's patches. (1998) (32)
Fibroblast activation protein expression in Crohn's disease strictures. (2009) (30)
Recent advances in gut immunology (2017) (30)
Always one step ahead: How pathogenic bacteria use the type III secretion system to manipulate the intestinal mucosal immune system (2011) (29)
Limit dilution analysis of mast cell precursor frequency in the gut epithelium of normal and Trichinella spiralis infected mice (1986) (29)
CC-10004 but not thalidomide or lenalidomide inhibits lamina propria mononuclear cell TNF-α and MMP-3 production in patients with inflammatory bowel disease. (2009) (29)
Discovery of a First-in-Class Receptor Interacting Protein 2 (RIP2) Kinase Specific Clinical Candidate, 2-((4-(Benzo[ d]thiazol-5-ylamino)-6-( tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl Dihydrogen Phosphate, for the Treatment of Inflammatory Diseases. (2019) (29)
Abnormal thymic stromal lymphopoietin expression in the duodenal mucosa of patients with coeliac disease (2015) (29)
Phenotypic Characterization of CD3−7+ Cells in Developing Human Intestine and an Analysis of Their Ability to Differentiate into T Cells 1 (2005) (29)
Effect of Tumor Necrosis Factor-&agr; Blockade on Mucosal Addressin Cell-adhesion Molecule-1 in Crohn's Disease (2013) (28)
Stromelysin-1 and macrophage metalloelastase expression in the intestinal mucosa of Crohn's disease patients treated with infliximab (2009) (27)
Cell-mediated immune injury in the intestine. (1992) (27)
A CD3-specific antibody reduces cytokine production and alters phosphoprotein profiles in intestinal tissues from patients with inflammatory bowel disease. (2014) (27)
High frequency of CD8 alpha alpha homodimer-bearing T cells in human fetal intestine. (1994) (26)
The Role of Cytokines in the Fibrotic Responses in Crohn’s Disease (2017) (26)
Enhanced Expression of Interferon Regulatory Factor-1 in the Mucosa of Children with Celiac Disease (2003) (25)
Ontogeny and induction of adhesion molecule expression in human fetal intestine (1993) (25)
Lymphokine secretion and proliferation of intraepithelial lymphocytes from murine small intestine. (1992) (25)
Increased expression of mucosal addressin cell adhesion molecule 1 in the duodenum of patients with active celiac disease is associated with depletion of integrin alpha4beta7-positive T cells in blood. (2009) (25)
Immunopathogenesis of Crohn's disease. (2005) (25)
Inside the microbial and immune labyrinth: Totally gutted (2010) (25)
Regulation of human intestinal T-cell responses by type 1 interferon-STAT1 signaling is disrupted in inflammatory bowel disease (2016) (24)
Serum concentrations of tumour necrosis factor in childhood chronic inflammatory bowel disease (2006) (24)
Urinary Growth Hormone in Growth‐Impaired Children with Chronic Inflammatory Bowel Disease (1993) (24)
T-bet controls intestinal mucosa immune responses via repression of type 2 innate lymphoid cell function (2018) (24)
Distribution, proliferation, and function of Paneth cells in uncomplicated and complicated adult celiac disease. (2008) (23)
Activated STAT4 and a Functional Role for IL-12 in Human Peyer’s Patches1 (2003) (22)
Cow’s milk protein‐specific T‐helper type I/II cytokine responses in infants with necrotizing enterocolitis (2009) (22)
High Expression of the “A Disintegrin And Metalloprotease” 19 (ADAM19), a Sheddase for TNF-&agr; in the Mucosa of Patients with Inflammatory Bowel Diseases (2013) (22)
Increased mucosal damage during parasite infection in mice fed an elemental diet. (1980) (21)
Recent advances in understanding Crohn’s disease (2013) (21)
Decoy receptor springs to life and eases fibrosis (2006) (20)
Interleukin-21 in cancer immunotherapy (2012) (20)
Nippostrongylus brasiliensis: mast cell kinetics at small intestinal sites in infected rats. (1980) (20)
T cell receptor V beta expression by mucosal T cells. (1991) (20)
Transmission disequilibrium test of stromelysin-1 gene variation in relation to Crohn’s disease (2004) (20)
Transcriptional regulation of the mucosal immune system mediated by T-bet (2010) (20)
Reprogramming the Immune System in IBD (2012) (19)
Intestinal immune cells in Strongyloides stercoralis infection. (1997) (19)
The challenges of stratifying patients for trials in inflammatory bowel disease. (2013) (19)
Connective tissue growth factor expression is increased in collagenous colitis and coeliac disease (2010) (19)
TNF alpha secreting cells in normal and diseased human intestine. (1995) (18)
Principles of Mucosal Immunology (2020) (18)
Binding of Intimin from Enteropathogenic Escherichia coli to Lymphocytes and Its Functional Consequences (2003) (18)
Inhibition of colon carcinogenesis by 2-methoxy-5-amino-N-hydroxybenzamide, a novel derivative of mesalamine. (2010) (18)
Phenotypic characterization of CD3–7+ cells in developing human intestine and an analysis of their ability to differentiate into T cells (2005) (18)
The immunologic basis for gastrointestinal food allergy (2009) (18)
Overview of role of the immune system in the pathogenesis of inflammatory bowel disease. (2006) (17)
Oral Anti-Tumour Necrosis Factor Domain Antibody V565 Provides High Intestinal Concentrations, and Reduces Markers of Inflammation in Ulcerative Colitis Patients (2019) (17)
Compartmentalised expression of meprin in small intestinal mucosa: enhanced expression in lamina propria in coeliac disease (2007) (17)
Multigenic control of resistance to Yersinia enterocolitica in inbred strains of mice (1988) (16)
Ontogeny of the mucosal immune response (2004) (16)
Preclinical evaluation of EPHX2 inhibition as a novel treatment for inflammatory bowel disease (2019) (16)
Blocking Smad 7 restores TGF-b 1 signaling in chronic inflammatory bowel disease (2018) (15)
Diarrhoeal disease: current concepts and future challenges. Intestinal cytokines in inflammatory bowel disease and invasive diarrhoea. (1993) (15)
Distribution and density of TNF immunoreactivity in chronic inflammatory bowel disease. (1995) (15)
The role of activated T cells in transformed intestinal mucosa. (1990) (15)
Viral vectors expressing immunoregulatory cytokines to treat inflammatory bowel disease (1998) (15)
Targeting interleukin-21 in immune-mediated pathologies. (2010) (14)
Finger clubbing and tumour necrosis factor α (1990) (14)
Autistic enterocolitis; is it a histopathological entity? Commentary (2007) (13)
The Role of Galectin-1 and Galectin-3 in the Mucosal Immune Response to Citrobacter rodentium Infection (2014) (13)
Ontogenetic aspects of the intestinal immune system in man (1992) (13)
Development of gastrointestinal immune function and its relationship to intestinal disease (1993) (13)
Interleukin-2 and interferon-γ producing cells in the lamina propria in celiac disease (1994) (13)
Involvement of CD40–CD40 Ligand in Uncomplicated and Refractory Celiac Disease (2011) (13)
Functional characterization of Con A-responsive Lyt2-positive mouse small intestinal intraepithelial lymphocytes. (1986) (13)
Oral Tolerance: Eating your way towards immunosuppression (1994) (13)
Osteopontin: a new addition to the constellation of cytokines which drive T helper cell type 1 responses in Crohn’s disease (2005) (12)
Human Neutrophil Elastase Proteolytic Activity in Ulcerative Colitis Favors the Loss of Function of Therapeutic Monoclonal Antibodies (2020) (12)
T cell receptor V beta expression in human intestine: regional variation in postnatal intestine and biased usage in fetal gut. (1996) (12)
A functional IL1RL1 variant regulates corticosteroid-induced sST2 expression in ulcerative colitis (2017) (12)
P027 FUNCTIONAL MODULATION OF CROHN'S DISEASE MYOFIBROBLASTS BY ANTI-TNF ANTIBODIES (2007) (11)
The significance of ileocolonic lymphoid nodular hyperplasia in children with autistic spectrum disorder. (2006) (11)
Alpha beta T cell receptor expression in rat intestinal epithelium. (1989) (11)
The opposing roles of IL-21 and TGFβ1 in chronic inflammatory bowel disease. (2011) (11)
Mucosal T cells (1998) (11)
WITHDRAWN: A Functional Role for Interleukin-21 in Promoting the Synthesis of the T Cell Chemoattractant, MIP-3α, by Gut Epithelial Cells (2006) (10)
Suppressor T cells, rebranded as regulatory T cells, emerge from the wilderness bearing surface markers (2002) (10)
A rapid diagnostic test for human regulatory T cell function to enable regulatory T cell therapy (2011) (10)
Aryl Hydrocarbon Receptor Interacting Protein Maintains Germinal Center B Cells through Suppression of BCL6 Degradation (2019) (10)
The worm turns on Helicobacter pylori (2001) (9)
Increased division of αβ TCR+ and γδ TCR+ intestinal intraepithelial lymphocytes after oral administration of cholera toxin (1996) (9)
Development of mucosal immune function in man: potential for Gl disease states (1994) (9)
Toothpaste and Crohn's disease (1990) (9)
Enhancement and suppression of the Peyer's patch immune response by systemic priming. (1982) (9)
Cytotoxic alpha/beta+ and gamma/delta+ T cells in murine intestinal epithelium. (1990) (9)
Immunology of Gastrointestinal Disease (1992) (9)
Contact sensitivity in the germ-free mouse. (1978) (9)
Gastrointestinal and hepatic immunology: Lymphoid cells and tissues of the gastrointestinal tract (1994) (9)
Interleukin-22 regulates neutrophil recruitment in ulcerative colitis and is associated with resistance to ustekinumab therapy (2022) (8)
Interleukin-2 and interferon-gamma producing cells in the lamina propria in celiac disease. (1994) (8)
A mouse model of intestinal fibrosis? (2003) (8)
Lack of Evidence for Small Intestinal Mucosal T-Cell Activation as a Pathogenic Mechanism in African HIV-Associated Enteropathy (2001) (8)
Nonspecific resistance to infection expressed within the Peyer's patches of the small intestine (1982) (8)
Activated T cells and macrophages in the intestinal mucosa of children with inflammatory bowel disease (1990) (8)
Cytokine gene deleted mice in the study of gastrointestinal inflammation. (1997) (8)
Comparison of cytokine and phosphoprotein profiles in idiopathic and Crohn’s disease-related perianal fistula (2019) (8)
Selective death of T cell receptor gamma/delta+ intraepithelial lymphocytes by apoptosis. (1990) (8)
Advances in Mucosal Immunology (1990) (8)
Insights provided by the study of the small intestine in the child and the foetus. (1989) (7)
Editorial: Intestinal Homeostasis and Disease: A Complex Partnership Between Immune Cells, Non-Immune Cells, and the Microbiome (2019) (7)
Preclinical development of a bispecific TNFα/IL-23 neutralising domain antibody as a novel oral treatment for inflammatory bowel disease (2021) (7)
The exposure of infants to Lactobacillus rhamnosus GG in Finland. (2006) (7)
Aetiology of Crohn's disease. (1993) (7)
Development of human gut-associated lymphoid tissue. (1987) (7)
Host responses to infection with Yersinia enterocolitica. (1979) (7)
New cytokine targets in inflammatory bowel disease. (2011) (7)
Effect of Narrow Spectrum Versus Selective Kinase Inhibitors on the Intestinal Proinflammatory Immune Response in Ulcerative Colitis (2016) (7)
Ontogenetic aspects of the intestinal immune system in man (1995) (7)
Antigen presenting cells and T cell interactions in the gastrointestinal tract. (2009) (6)
Smad 7 induces plasticity in tumor-infiltrating Th 17 cells and enables TNF-alpha-mediated killing of colorectal cancer cells (2014) (6)
The immunologic basis for celiac disease and related disorders. (1996) (6)
Gut immunology. (1990) (6)
Modulation in vivo of Lyt 2 antigen expression on T cells by anti-Lyt 2 antibody: effects on Con A-induced unresponsiveness. (1986) (5)
Advances in mucosal immunology : proceedings of the Fifth International Congress of Mucosal Immunology (1990) (5)
Chapter 22 – Human Gut-Associated Lymphoid Tissues (2005) (5)
Oxpentifylline, tumour necrosis factor-alpha and Crohn's disease. (1997) (5)
Relationship between the extent of mucosal T cell and macrophage activation and mucosal damage (1995) (5)
Impaired rejection and mucosal injury of small intestinal allografts lacking the interferon‐γ receptor (2003) (5)
Ontogenetic aspects of the intestinal immune system in man (1992) (5)
Upregulation of Keratinocyte Growth Factor during T‐Cell Immunity in the Gut Mucosa (1998) (5)
Changes inintraepithelial lymphocyte subpopulations incoeliac disease andenteropathy associated Tcell lymphoma (malignant histiocytosis oftheintestine) (1989) (4)
A p55 tumor necrosis factor-α (TNF) receptor immunoadhesin prevents T cell-mediated intestinal injury by inhibiting matrix metalloproteinase production (1998) (4)
Biological therapy in Crohn's disease. (2003) (4)
Adaptive Immunity: Effector and Inhibitory Cytokine Pathways in Gut Inflammation (2010) (4)
Expression of cell adhesion molecules in the fetal gut. (1995) (4)
171 MACROPHAGE INFILTRATION AND MATRIX DISRUPTION IN∼RDS (1994) (4)
Chapter 17 – Phylogeny of the Gut-Associated Lymphoid Tissue (GALT) (2005) (4)
Inflammatory Bowel Disease and ADAM 17 Deletion (2012) (3)
Hypersensitivity reactions in the small intestine. IV. Influence of allograft rejection on small intestinal mucosal architecture: a scanning and transmission electron microscope study. (1978) (3)
Depletion of the enteric nervous system by gene targeting results in haemorrhagic necrosis of the ileum (1998) (3)
In vitro enteropathy (1992) (3)
The Biochemical Basis of Immune Enteropathy (2002) (3)
Cytokine regulation of intestinal epithelial cell proliferation (2010) (3)
Antigen-Independent and Antigen-Dependent Development of Mucosal Immunity and Hypersensitivity (1993) (3)
Transforming Growth Factor-β Signaling and Matrix Metalloproteinase Pattern in Intestinal Strictures in Crohn's Disease (2006) (3)
386 - Non-Interventional Cohort Study of the Relative Incidence of Major Cardiovascular Events Among Patients Initiating Prucalopride versus a Matched Comparator Cohort Initiating Polyethylene Glycol 3350 (PEG) (2018) (3)
Subsets of gamma/delta T cells in human intestinal epithelium (1990) (2)
The cells and tissues of the gastrointestinal tract (1992) (2)
O0004 INFANTILE ALLERGIC COLITIS (AC): A HETEROGENOUS TH1/TH2 FOOD MEDIATED MUCOSAL INFLAMMATION? (2004) (2)
T CELL RECEPTOR EXPRESSION BY HUMAN INTRAEPITHELIAL LYMPHOCYTES; DIFFERENCES BETWEEN COELIAC DISEASE AND NORMAL JEJUNAL BIOPSIES IN NON-COELIAC ENTEROPATHY (1989) (2)
Detection of chicken antibody to the protozoan parasite Eimeria tenella by antigen-coated microspheres. (1986) (2)
Cytokine Regulation of Gut Inflammation in IBD (2010) (2)
P668 Measured and modelled data suggest that oral administration of V565, a novel domain antibody to TNF-alpha, could be beneficial in the treatment of IBD (2018) (2)
Intestinal dendritic cells in coeliac disease (2006) (2)
HLA-DRexpression inhumanfetal intestinal epithelium (1988) (2)
241 Interleukin (IL)-25 Inhibits IL-12 Production and TH1 Cell-Driven Inflammation in the Gut (2009) (2)
Discovery of a First-in-Class Receptor Interacting Protein 2 (RIP2) Kinase Specific Clinical Candidate, 2-((4-(Benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl Dihydrogen Phosphate, for the Treatment of Inflammatory Diseases. (2019) (2)
An OX40 fusion protein prevents colitis in mice (1998) (2)
THE EFFECTS OF STROMELYSIN OR MATRIX METALLOPROTEINASE-3 (MMP-3) ON INTESTINAL SECRETORY FUNCTION (1998) (2)
Mucosal immunity in human chronic helminthic disease and gut inflammation. (1992) (2)
P.1.61: INVOLVEMENT OF MACROPHAGES IN INTESTINAL STRICTURES IN CROHN'S DISEASE (2011) (1)
An Unusual Case of Colonic Lymphoid Nodular Hyperplasia in an Adolescent Patient (2011) (1)
OC.01.1 DIFFERENTIAL DEGRADATION OF ANTI-TUMOR NECROSIS FACTOR-ALPHA AGENTS BY MATRIX METALLOPROTEINASE-12 IN INFLAMMATORY BOWEL DISEASE (2010) (1)
Abstracts of the 4th Meeting of the ‘Association Française pour l’Etude du Foie’ (1978) (1)
Cytokines and Growth Factors in Gastroenterology. Bailliere's Clinical Gastroenterology 10:1 (1996) (1)
T CELL-MEDIATED DAMAGE IN THE HUMAN COLON IN ORGAN CULTURE A NEW IN-VITRO MODEL OF COLITIS (1989) (1)
Tu1677 Down-Modulation of Intestinal Production of Pro-Inflammatory Cytokines in Experimental Colitis and in Inflammatory Bowel Disease by a Narrow Spectrum Kinase Inhibitor (2013) (1)
Inflammatory bowel disease in children. (1994) (1)
Lack of evidence for interferon-gamma as a mediator in a graft-rejection model of enteropathy (1998) (1)
Lymphokine production by T lymphocytes isolated from murine small intestinal epithelium. (1985) (1)
T HELPER 2 (TH2) CYTOKINES IN THE RESPONSE OF NEWBORN HUMAN INFANTS TO COW'S MILK PROTEINS (1998) (1)
M1803 Differential Degradation of Anti-Tumor Necrosis Factor-α Agents by Matrix Metalloproteinase-12 in Inflammatory Bowel Disease (2010) (1)
OC.07.1 MICRO-RNA EXPRESSION PROFILING IDENTIFIES MIR-29B AS A RELEVANT PRO-FIBROGENIC FACTOR IN CROHN'S DISEASE INTESTINAL STRICTURES (2013) (1)
P057 Micro-RNA expression profiling identifies miR-29b as a relevant pro-fibrogenic factor in Crohn's disease intestinal strictures (2013) (1)
STROMELYSIN AND TIMP-1 EXPRESSION IN CHILDREN WITH INFLAMMATORY BOWEL DISEASE AND NORMAL CONTROLS. (1998) (1)
T-Cell Subpopulations in Intestinal Mucosa (1991) (1)
SYSTEM IN INFLAMMATORY BOWEL DISEASE (2008) (1)
Targeted inhibition of Smad7 with a specific antisense oligonucleotide facilitates TGF-β1-mediated suppression of mucosal inflammation (2006) (1)
Isolation and function of mucosal lymphocytes in the mouse. (1985) (1)
Mucosal changes induced by ischemia–reperfusion injury in a jejunal loop transplanted in oropharynx (2013) (1)
P0147 PP EVIDENCE OF COW???S MILK PROTEIN (CMP) SENSITISATION IN NEONATAL NECROTISING ENTEROCOLITIS (NEC) (2004) (1)
Analysis ofTH1 andTH2 cytokine production in lowgrade B cell gastricMALT-typelymphomas stimulated invitro withHelicobacter pylori (1997) (1)
The Pharmacological Profile of TOP1288, a Narrow Spectrum Kinase Inhibitor (NSKI) in Clinical Development as an Anti-Inflammatory Treatment for Ulcerative Colitis (2017) (1)
SMAD7 EXPRESSION IN T CELLS PROTECTS FROM COLITIS-ASSOCIATED COLORECTAL CANCER (2009) (1)
P105 Human neutrophil elastase degrades the therapeutic monoclonal antibodies effective in IBD (2018) (1)
T lymphocyte populations within the lamina propria (2020) (1)
Alpha/beta T cell receptor expression in the intestinal epithelium of rodents (1990) (1)
Regulation of matrix metalloproteinases (MMPs) synthesis by interleukin-21 (IL-21) in human intestinal fibroblasts (2006) (1)
P019 The role of human neutrophil elastase and its inhibitor elafin in ulcerative colitis (2013) (1)
T-regulatory cells in Crohn's disease patients treated with infliximab (2008) (1)
P267 - Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression (2009) (1)
Colonic lymphoid nodular hyperplasia in an adolescent. (2011) (1)
Aryl hydrocarbon receptor interacting protein maintains germinal center B cells through suppression of BCL 6 degradation (2019) (1)
P032 The pharmacological profile of TOP1288, a narrow spectrum kinase inhibitor in clinical development as an anti-inflammatory treatment for ulcerative colitis. (2017) (1)
OC.06.7: EFFECT OF MATRIX METALLOPROTEINASE (MMP)-3, -8, -10 AND -12 ON THE STRUCTURE AND FUNCTION OF ANTI-TUMOR NECROSIS FACTOR-ALPHA AGENTS IN INFLAMMATORY BOWEL DISEASE (2011) (1)
T1268 Mucosal Addressin Cell Adhesion Molecule-1 in Celiac Disease (2008) (0)
Preclinical Development of a Novel, Orally-Administered Anti-Tumour Necrosis Factor Domain Antibody for the Treatment of Inflammatory Bowel Disease (2018) (0)
Human peyer's patches are an inductive site for T helper cell type 1 responses to dietary antigen (2000) (0)
Sa1777 Ex Vivo Activation of Triggering Receptor Expressed on Myeloid Cells 1 Enhances the Production of PRO-Inflammatory Cytokines by Inflammatory Bowel Disease Mucosa (2013) (0)
Cytokines instools ofchildren withinflammatory boweldisease orinfective diarrhoea (1993) (0)
Epithelial growth factors in Coeliac Disease (2001) (0)
Celiac disease (gluten-sensitive enteropathy) (1992) (0)
PC.01.2 SMAD7 SUSTAINS COLON CANCER CELL GROWTH BY MODULATING PP1 AND EIF2-ALPHA TO REGULATE CDC25A (2014) (0)
Gut Development and Immunology (2006) (0)
A functional role of interleukin-21 (IL-21) in promoting matrix metalloproteinases synthesis by gastric epithelial cells during helicobacter pylori infection (2006) (0)
M1787 Interleukin-25 Production is Differently Regulated by TNF-α and TGF-β1 in the Human Gut (2010) (0)
P.59 HIGH IFN-GAMMA EXPRESSION IS REQUIRED FOR TUMOR PROTECTION IN A MODEL OF COLITIS-ASSOCIATED COLORECTAL CANCER (2010) (0)
2 - Targeting gut T cell Ca2+ release-activated Ca2+ channels inhibits Th1 cytokine production and T-box transcription factor T-bet in inflammatory bowel disease (2009) (0)
Subject Index, Vol. 46, Supplement 2, 1990 (1990) (0)
IMMUNOHISTOCHEMICAL AND ULTRASTRUCTURAL STUDY OF THE MUSCULARIS MUCOSAE AND THE PERICRYPT CELLS IN THE DEVELOPING HUMAN INTESTINE (1991) (0)
Nutrition and immunology (contemporary issues in clinical nutrition vol. 11): edited by Ranjit K. Chandra, Alan R. Liss, 1988. $96.00 (viii + 342 pages) ISBN 0 8451 1203 1 (1988) (0)
517 T Cell-Specific Smad7 Over-Expression Reduces Regulatory T Cell-Mediated Control of Colitis (2008) (0)
104 THE MUCOSAL T CELL CYTOKINE RESPONSE IN CHILDREN IS DOMINATED BY INTERFERON-γ. (1996) (0)
P294 - Control of interleukin-17 production in inflammatory bowel disease (2009) (0)
272 In Vitro Generated Regulatory T Cells From Crohn's Disease Patients’ Blood Home to Inflamed Human Small Bowel In Vivo (2013) (0)
Interferon gamma andinterleukin 4secreting cells inthegastric antruminHelicobacter pylori positive andnegativegastritis (1995) (0)
P256 The Endocannabinoid System in Inflammatory Bowel Disease (2008) (0)
684 Gastrointestinal Events and Adverse Reactions on Selective and Non Selective Cyclooxygenase Inhibitors in the Large Randomised Controlled SCOT Trial (2016) (0)
W1167 Activation and Modulation of the MAP Kinase Pathway in IBD (2008) (0)
1 CHANGES IN MUCOSAL MORPHOLOGY AND THE RATE OF CRYPT CELL RENEWAL INDUCED BY A CELL MEDIATED IMMUNE RESPONSE IN HUMAN SMALL INTESTINE (1988) (0)
Bacteria and the regulation of T-cell immune function in the gut (2002) (0)
Lacking IL-12 or IFN-, in Mice Citrobacter rodentium Pathogen , Attaching-Effacing Enteric Bacterial During Infection with a Noninvasive , Impaired Resistance and Enhanced Pathology (2002) (0)
T-bet controls intestinal mucosa immune responses via repression of type 2 innate lymphoid cell function (2018) (0)
Tumournecrosis factor inthebronchoalveolar secretions ofinfants withtherespiratory distress syndrome andtheeffect ofdexamethasone treatment (1992) (0)
P020 Interleukin-17A but not interleukin-17E is profibrotic in the gut of patients with Crohn's disease (2012) (0)
P.63 INTERLEUKIN (IL)-17A BUT NOT IL-17E IS PROFIBROTIC IN CROHN'S DISEASE (2010) (0)
THE DEVELOPMENT AND FUNCTIONAL ACTIVITY OF T-CELLS IN HUMAN FOETAL SMALL INTESTINE (2004) (0)
Control of mucosal immune responses by transforming growth factor-β (2007) (0)
Sa1839 The Role of Human Neutrophil Elastase and Its Inhibitor Elafin in Ulcerative Colitis (2013) (0)
M1956 High IFN-Gamma Expression is Required for Tumor Protection in a Model of Colitis-Associated Colorectal Cancer (2010) (0)
Sa1250 Thymic Stromal Lymphopoietin Is Primarily Reduced in Untreated Celiac Disease Mucosa (2013) (0)
P157 TRANSFORMING GROWTH FACTOR-BETA BLOCKADE UP-REGULATES T-BET EXPRESSION AND INCREASES PROINFLAMMATORY CYTOKINES AND STROMELYSIN-1 (MMP-3) IN NORMAL COLONIC MUCOSA (2007) (0)
W1230 CD4+Cd25highfoxp3+ T-Regulatory Cells in Crohn's Disease Patients Treated with Infliximab (2008) (0)
795: AN INTERLEUKIN 22/CHEMOKINE AXIS DRIVES COLONIC NEUTROPHIL RECRUITMENT AND TREATMENT RESISTANCE IN ULCERATIVE COLITIS (2022) (0)
The role of IL-12 and IFN-gamma in immunity to Citrobacter rodentium infection (2001) (0)
Keratinocyte growth factor (FGF-7) and its role in mediating the crypt hyperplasia seen during T cell hypersensitivity in the gut (1998) (0)
Matrix Metalloproteinase Production Cell-Mediated Intestinal Injury by Inhibiting A p 55 TNF Receptor Immunoadhesin Prevents T Ashkenazi (1998) (0)
Host defenses in murine malaria: failure of vaccination with formolized blood parasites to protect athymic mice from Plasmodium berghei (1980) (0)
O11 CURCUMIN SUPPRESSES P38 MAPK ACTIVATION, REDUCES IL-1BETA AND MMP-3, AND ENHANCES IL-10 EXPRESSION IN THE MUCOSA OF PATIENTS WITH INFLAMMATORY BOWEL DISEASE (2009) (0)
Ontogenetic aspects of the intestinal immune system in man (1995) (0)
The characterization of apoptosis in neonatal T lymphocytes (1997) (0)
The mucosal immune system in human immunodeficiency virus infection (1992) (0)
Inflammatory bowel disease in knockout mice The development of gastrointestinal inflammation in recently generated gene-knockout mice suggests that inflammatory bowel disease in man may be caused by an inappropriate immune response to normal bacteria. (1994) (0)
OC.07.2 SELECTIVE INHIBITION OF RIP2 KINASE ACTIVITY REDUCES PRO-INFLAMMATORY CYTOKINE PRODUCTION IN INFLAMMATORY BOWEL DISEASE MUCOSA (2013) (0)
INTERLEUKIN (IL)-25 INHIBITS IL-12 PRODUCTION AND TH1 CELL-DRIVEN INFLAMMATION IN THE GUT (2009) (0)
OC.06.3: EVIDENCE FOR AN ANTI-FIBROGENIC ROLE OF ANANDAMIDE IN CROHN'S DISEASE (2011) (0)
THE RESPONSE OF PEYER'S PATCH(PP) T CELLS TO COW'S MILK PROTEIN IN CHILDREN (1999) (0)
Mo1724 Interleukin-17A Homodimer Reduces Pro-Inflammatory Cytokine Production by Inflammatory Bowel Disease Mucosa Cultured Ex Vivo (2015) (0)
Corrigendum: The endogenous cannabinoid system in the gut of patients with inflammatory bowel disease (2011) (0)
P.11.1 THYMIC STROMAL LYMPHOPOIETIN IS PRIMARILY REDUCED IN REFRACTORY COELIAC DISEASE DUODENAL MUCOSA (2014) (0)
Book review: Principles of Mucosal Immunology (2013) (0)
Human T Lymphocytes Autocrine Regulation of IL-21 Production in MacDonald (2008) (0)
T-bet deficiency in the innate immune compartment exacerbates T-cell mediated intestinal inflammation (2010) (0)
A functional IL1RL1 variant regulates corticosteroid-induced sST2 expression in ulcerative colitis (2017) (0)
Analysis of Their Ability to Differentiate into in Developing Human Intestine and an Cells + 7 − Phenotypic Characterization of CD 3 and (2005) (0)
Gelatinases Synthesis-Infected Gastric Mucosa and Promotes pylori Helicobacter IL-21 Is Highly Produced in Monteleone (2007) (0)
P036 Involvement of gut macrophages in the fibrogenic process in Crohn's disease (2012) (0)
Ligand-IgG Fusion Protein OX 40-IgG Fusion Protein , But Not with an Inflammatory Bowel Disease with an Interaction : Amelioration of Ongoing In Vivo by Targeting the OX 40-OX 40 Ligand Regulation of T Cell Activation In Vitro and (1998) (0)
Matrix Metalloproteinases in Gut Injury (1997) (0)
P054 Interactions between neutrophil elastase and biologics in IBD (2014) (0)
Modulation of Th1 responses, tissue injury and matrix metalloproteinases in human gut (2000) (0)
A FUNCTIONAL RELATIONSHIP BETYEN DELAYED HYPERSENSITIVTIY AND ANTIBACTERIAL IMUNITY (1981) (0)
P.05.15 IS ULCERATIVE COLITIS AN ATYPICAL T HELPER 2-MEDIATED DISEASE CHARACTERISED BY EXCESSIVE PRODUCTION OF INTERLEUKIN-13? (2012) (0)
Transforming growth factor-beta signaling and matrix metalloproteinase pattern in intestinal strictures in Crohn's disease (2006) (0)
T Cell-Mediated Immunity and Tissue Damage in the Gut (1993) (0)
Proteases and the gut barrier (2012) (0)
53 Infantile Allergic Colitis: A Heterogenous T-Helper Type 1/ T-Helper Type 2 Food Mediated Mucosal Inflammation? (2004) (0)
Ontogenetic aspects of the intestinal immune system in man (1995) (0)
EVIDENCE BASED GASTROENTEROLOGY ADVISORY GROUP (2002) (0)
Mucosal adaptation and destruction in response to lamina propria T cell activation in explants of human fetal intestine. (1995) (0)
9 PS Defective TGF-beta activity contributes to the sustained NF-kB activation in chronic intestinal inflammation (2002) (0)
FUNCTIONAL STUDIES ON CELLS FROM HUMAN PEYER'S PATCHES. THEIR PHENOTYPE AND IN VITRO PROLIFERATIVE RESPONSES (1986) (0)
The role of interferon-alpha in the small intestine enteropathy (2000) (0)
Increased bacterial burden and inflammation in TNF receptor knockout mouse infected with Citrobacter rodentium (mouse EPEC) (2000) (0)
Subject Index Vol. 62, 2000 (2000) (0)
103 DISTRIBUTION OF DIVIDING T CELLS THROUGHOUT THE BOWEL WALL IN INFLAMMATORY BOWEL DISEASE (1996) (0)
64 DISTRIBUTION OF TNF IMMUNOREACTIVITY IN NORMAL INTESTINE, CROHN'S DISEASE AND ULCERATIVE COLITIS (1992) (0)
Essentials of Mucosal Immunology (1997) (0)
P073 Ex vivo activation of triggering receptor expressed on myeloid cells 1 enhances the production of pro-inflammatory cytokines by inflammatory bowel disease mucosa (2013) (0)
Measles vaccination as a risk factor for inflammatory bowel disease. (1995) (0)
Insights provided bythestudy ofthesmall intestine inthechild andthefoetus (1989) (0)
P.06.8 T HELPER 2 CELLS ARE NOT INCREASED, WHEREAS NATURAL KILLER T CELLS ARE REDUCED IN THE INFLAMED MUCOSA OF ULCERATIVE COLITIS PATIENTS (2014) (0)
Intestinal lymphoid cells (1987) (0)
2013 Digestive Disease Week. AGA-Horizon Pharma Fellow Abstract Prize (2013) (0)
P037 Is ulcerative colitis an atypical Th2-mediated disease characterised by excess production of interleukin-13? (2012) (0)
52 Smad7 Expression in T Cells Protects from Colitis-Associated Colorectal Cancer (2009) (0)
The tissue cytokine profile in acute dextran sulfate (DSS) induced mucosal injury in mice is similar td that observed in Crohn's disease (1999) (0)
994 T-bet Regulates Cytokine Expression by Intestinal Innate Lymphoid Cells (2012) (0)
P002 Intestinal homeostasis is critically regulated by the transcription factor T-bet (2013) (0)
fetal colon . goblet cell depletion in cultured human induces crypt epithelial proliferation and Activation of lamina propria T cells (2006) (0)
Production by Colonic γ Human Intestinal Mucosa and Enhance IFN-T Cells Populate the + 2 δ Proinflammatory V and (2013) (0)
OC.05.7: PROTECTIVE EFFECTS OF TIMP-3 ON GUT INFLAMMATION (2011) (0)
For peer review only Methodology of a large streamlined safety study: protocol of the Standard care versus Celecoxib Outcome Trial (SCOT trial) (2012) (0)
45 ANTIBODY RESPONSE TO YERSINIA ENTEROCOLITICA IN SERUM AND SALIVA OF THALASSAEMIC CHIDREN (1988) (0)
TH17 Cells and IL-23 in Gut Inflammation (2011) (0)
TNBS-induced murine colitis: Bone marrow stem cell modulation of inflammatory bowel disease (2003) (0)
P272 EFFECT OF INFLIXIMAB ON CD4+CD25HIGHFOXP3+ T-REGULATORY CELLS IN CROHN'S DISEASE (2008) (0)
PP1700 大腸憩室症におけるMatrix MetalloproteinaseとTissue Inhibitor of Metalloproteinaseの検討 (2001) (0)
Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2 (2020) (0)
52 In Vitro Evidence of Cow's Milk Protein Sensitisation in Neonatal Necrotising Enterocolitis (2004) (0)
Limiting dilution analysis of functional T cells in the gut mucosa. (1987) (0)
A functional relationship between delayed hypersensitivity and antibacterial immunity. (1981) (0)
Tu1921 Selective Inhibitors of RIP2 Kinase Activity Reduce PRO-Inflammatory Cytokine Production in IBD Mucosal Biopsy Cultures and Inflammation in Murine TNBS-Induced Colitis (2012) (0)
23 Autocrine Regulation of Interleukin-21 Production in Human Peripheral Blood and Intestinal T Lymphocytes (2008) (0)
HIGH INTERLEUKIN-17A (IL-17A) EXPRESSION IN CELIAC DISEASE MUCOSA (2009) (0)
Increased expression oflaminin/collagen receptor (VLA-1)onepithelium ofinflamed human intestine (1990) (0)
Technique for microdissection and measurement in biopsies ofhuman small intestinc MEASUREMENTS OF CRYPTS AND VILLI (2004) (0)
OC.05.2 TH17-RELATED CYTOKINES AND EXCESSIVE ACTIVATION OF STAT3 SUSTAIN COLORECTAL CANCER CELL GROWTH (2014) (0)
Plummer & Vinson of the Plummer-Vinson syndrome (1999) (0)
intestinal epithelium . HLA-DR expression in human fetal (0)
Regulation of Matrix Metalloproteinases Synthesis by Interleukin-21 in Human Intestinal Fibroblasts (2006) (0)
OC.16.1 INTERLEUKIN-17A HOMODIMER REDUCES PRO-INFLAMMATORY CYTOKINE PRODUCTION BY INFLAMMATORY BOWEL DISEASE MUCOSA CULTURED EX VIVO (2014) (0)
M2021 Increased Expression of Interleukin 17 in Celiac Disease Mucosa (2009) (0)
S28 T-regulatory cells in Crohn's disease patients treated with infliximab (2010) (0)
P.64 INTERLEUKIN-25 PRODUCTION IS DIFFERENTLY REGULATED BY TNF-α AND TGF-β1 IN THE HUMAN GUT (2010) (0)
Role of infliximab in downregulating stromelysin-1 (MMP-3) in crohn's disease (2006) (0)
P066 Human intestinal Vδ2+ T-cells promote mucosal inflammation in Crohn's disease and are selectively ablated by azathioprine therapy (2013) (0)
W1168 A Key Role for the Endocannabinoid System in Dampening T Helper Cell Type 1 Response in Inflammatory Bowel Disease (2008) (0)
Sa1855 Inhibition of Cytokine Release From HT-29 Cells and Ulcerative Colitis Biopsies Is Potentiated by Combination of Selective Kinase Inhibitors and Such Effects Are Mimicked by TOP1210, a Narrow Spectrum Kinase Inhibitor (NSKIi) (2016) (0)
5 OP Activated STAT4 and a functional role for IL-12 in peyer's patches explains the TH1 dominated responses of human gut-associated lymphoid tissue (2002) (0)
OC.02.2 HUMAN NEUTROPHIL ELASTASE CONTRIBUTES TO LOSS OF FUNCTION OF INFLIXIMAB IN ULCERATIVE COLITIS (2016) (0)
Mucosal Immunity — A Key to Tolerance (2001) (0)
The role of oral tolerance in food allergy (2002) (0)
P053 Interleukin-17A homodimer reduces pro-inflammatory cytokine production by inflammatory bowel disease mucosa cultured ex vivo (2014) (0)
Contents Vol. 62, 2000 (2000) (0)
2013 Digestive Disease Week. (2013) (0)
Serumconcentrations oftumournecrosis factorin childhood chronic inflammatory boweldisease (2011) (0)
A homozygous deletion mutation in ADAM17 underlies an autosomal recessive inflammatory skin and bowel disease (2011) (0)
Tu1915 Differential MicroRNA Expression Profiles in Crohn's Disease Strictured Versus Non-Strictured Intestine (2012) (0)
Protective Effects of Timp-3 on Gut Inflammation (2011) (0)
Spatiotemporal regulation of galectin-1-induced T-cell death in lamina propria from Crohn’s disease and ulcerative colitis patients (2021) (0)
Microenvironment and Immunology Smad 7 Expression in T cells Prevents Colitis-Associated Cancer (2011) (0)
171 EXPRESSION OF MATRIX METALLOPROTEINASE mRNA BY SMOOTH MUSCLE CELLS ISOLATED FROM THE MUCOSA OF CHILDREN WITH INFLAMMATORY BOWEL DISEASE. (1996) (0)
Immunopathogenesis of Crohn's disease. Discussion (2005) (0)
4D5.4, a monoclonal antibody which recognizes cells in inflamed human intestine. (1995) (0)
Su1266 In Vitro Generated Regulatory T Cells From Blood Suppress Mucosal Effector T Cells in Crohn's Disease Patients (2013) (0)
SAT-LB056 Is AIP a Tumor Suppressor or an Oncogene? AIP as a Novel Regulator of the Oncogene BCL6 in Diffuse Large B Cell Lymphoma (2019) (0)
pylori positive and negative gastritis . cells in the gastric antrum in Helicobacter Interferon gamma and interleukin 4 secreting (0)
Session 8: Probiotics in the defence and metabolic balance of the organism Probiotics and the immune response to vaccines (2010) (0)
T-Bet in Inflammatory Bowel Disease Production and T-Box Transcription Factor Channels Inhibits T Cell Cytokine 2 + Ca Release-Activated 2 + Targeting Gut T Cell Ca (2009) (0)
The neutrophil chemokine NAP-2 is proteolytically activated from intestinal epithelial cells by fibroblast matrix metalloproteinases (2003) (0)
23. V β3+ MUCOSAL T CELL ACTIVATION AND TISSUE DAMAGE IN HUMAN SMALL INTESTINE BY THE BACTERIAL SUPERANTIGEN STAPHYLOCOCCAL ENTEROTOXIN B (1993) (0)
P.12.22 MARKED ACTIVATION OF MUCOSAL PRO-INFLAMMATORY IMMUNE RESPONSE IN DIVERTICULITIS BUT NOT IN DIVERTICULOSIS (2013) (0)
Sa1771 Lack of Thymic Stromal Lymphopoietin Down-Regulation on Mucosal Pro-Inflammatory Cytokines in Refractory Coeliac Disease (2015) (0)
Metalloproteinase-3)-Deficient Mice Infection in Stromelysin-1 (Matrix Impaired Immunity to Intestinal Bacterial (2004) (0)
Tu1895 Does Interleukin (IL)-13 Have a Role in Sustaining the Mucosal PRO-Inflammatory Immune Response in Ulcerative Colitis and in Promoting Intestinal Fibrogenesis in Crohn's Disease? (2012) (0)
T cell receptor Vflexpression bymucosal T cells (1991) (0)
126 CYTOKINS PROFILES IN BLOOD, LAMINA PROFFIA (LP) AND FEYERʼS PATCH (PP) T-LYMPHOCYTES IN CHILDREN (1995) (0)
70 MODULATION OF T CELL‐MEDIATED IMMUNOPATHOLOGY IN HUMAN FETAL QUT IN VITRO (1992) (0)
OC.16.3 THE ROLE OF HUMAN NEUTROPHIL ELASTASE AND ITS INHIBITOR ELAFIN IN ULCERATIVE COLITIS (2014) (0)
PEYER'S PATCH (PP) T CELL RESPONSES TO COW'S MILK PROTEINS IN CHILDREN (1998) (0)
Cell-interactions in the splenic suppression caused by antigen-feeding. (1982) (0)
P.03.15 ACTIVATION OF TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1 INCREASES THE PRODUCTION OF PRO-INFLAMMATORY CYTOKINES IN INFLAMMATORY BOWEL DISEASE MUCOSA (2013) (0)
Sa1854 Effects of a Narrow Spectrum Kinase Inhibitor (NSKI) and Selective Kinase Inhibitors on the Intestinal Pro-Inflammatory Immune Response in Ulcerative Colitis (2016) (0)
TOOTHPASTE AND CROHN'S DISEASE. REPLY (1990) (0)

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