Thomas Unger
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(Suggest an Edit or Addition)Thomas Unger's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- International union of pharmacology. XXIII. The angiotensin II receptors. (2000) (2130)
- Atrial natriuretic factor—a circulating hormone stimulated by volume loading (1985) (1274)
- 2020 International Society of Hypertension Global Hypertension Practice Guidelines. (2020) (1254)
- The angiotensin AT2-receptor mediates inhibition of cell proliferation in coronary endothelial cells. (1995) (967)
- 2020 International Society of Hypertension global hypertension practice guidelines. (2020) (794)
- Quantitative real-time RT-PCR data analysis: current concepts and the novel “gene expression’s CT difference” formula (2006) (770)
- T-lymphocyte Infiltration in Visceral Adipose Tissue: A Primary Event in Adipose Tissue Inflammation and the Development of Obesity-Mediated Insulin Resistance (2008) (684)
- Contribution of kinins to the cardiovascular actions of angiotensin-converting enzyme inhibitors. (1995) (670)
- Angiotensin Type 1 Receptor Blockers Induce Peroxisome Proliferator–Activated Receptor-γ Activity (2004) (656)
- Repetitive, episodic hypoxia causes diurnal elevation of blood pressure in rats. (1992) (502)
- The role of the renin-angiotensin system in the development of cardiovascular disease. (2002) (498)
- Carotid chemoreceptors, systemic blood pressure, and chronic episodic hypoxia mimicking sleep apnea. (1992) (430)
- AT2 receptor stimulation increases aortic cyclic GMP in SHRSP by a kinin-dependent mechanism. (1998) (426)
- Angiotensin AT1/AT2 Receptors: Regulation, Signalling and Function (2003) (419)
- Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection. (2005) (418)
- Angiotensin synthesis in the brain and increased turnover in hypertensive rats. (1983) (322)
- Oxytocin unlike vasopressin is a stress hormone in the rat. (1983) (311)
- A Novel Signal Transduction Cascade Involving Direct Physical Interaction of the Renin/Prorenin Receptor With the Transcription Factor Promyelocytic Zinc Finger Protein (2006) (306)
- Hypertension caused by chronic intermittent hypoxia – influence of chemoreceptors and sympathetic nervous system (1997) (300)
- Hypertension in overweight and obese primary care patients is highly prevalent and poorly controlled. (2004) (296)
- Molecular characterization of new selective peroxisome proliferator-activated receptor gamma modulators with angiotensin receptor blocking activity. (2005) (286)
- Angiotensin AT2 receptor protects against cerebral ischemia‐induced neuronal injury (2005) (271)
- The endothelium and vascular inflammation in diabetes (2007) (270)
- The relevance of tissue angiotensin-converting enzyme: manifestations in mechanistic and endpoint data. (2001) (267)
- Angiotensin II and the fibroproliferative response to acute lung injury. (2004) (260)
- The AT2 receptor—A matter of love and hate (2005) (258)
- Brain angiotensin: pathways and pharmacology (1988) (256)
- Metabolic Actions of Estrogen Receptor Beta (ERβ) are Mediated by a Negative Cross-Talk with PPARγ (2008) (255)
- Sympathetic denervation blocks blood pressure elevation in episodic hypoxia. (1992) (251)
- Contributions of Inflammation and Cardiac Matrix Metalloproteinase Activity to Cardiac Failure in Diabetic Cardiomyopathy (2007) (249)
- Angiotensin II Type 2 Receptor Stimulation: A Novel Option of Therapeutic Interference With the Renin-Angiotensin System in Myocardial Infarction? (2008) (249)
- The angiotensin II AT2 receptor inhibits proliferation and promotes differentiation in PC12W cells (1996) (249)
- PPAR&ggr;-Activating Angiotensin Type-1 Receptor Blockers Induce Adiponectin (2005) (248)
- The Angiotensin II Type 2 (AT2) Receptor Promotes Axonal Regeneration in the Optic Nerve of Adult Rats (1998) (218)
- THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors (2021) (212)
- Enkephalin Effects on Blood Pressure, Heart Rate, and Baroreceptor Reflex (1980) (202)
- Direct Angiotensin II Type 2 Receptor Stimulation Acts Anti-Inflammatory Through Epoxyeicosatrienoic Acid and Inhibition of Nuclear Factor &kgr;B (2010) (194)
- Effects of telmisartan, irbesartan, valsartan, candesartan, and losartan on cancers in 15 trials enrolling 138 769 individuals (2011) (189)
- Angiotensin-converting enzyme inhibition improves cardiac function. Role of bradykinin. (1994) (186)
- The PHARAO study: prevention of hypertension with the angiotensin-converting enzyme inhibitor ramipril in patients with high-normal blood pressure – a prospective, randomized, controlled prevention trial of the German Hypertension League (2008) (185)
- Blockade of central angiotensin AT(1) receptors improves neurological outcome and reduces expression of AP-1 transcription factors after focal brain ischemia in rats. (1999) (178)
- Renin-angiotensin system blockade and cognitive function in patients at high risk of cardiovascular disease: analysis of data from the ONTARGET and TRANSCEND studies (2011) (176)
- Cellular distribution of angiotensin-converting enzyme after myocardial infarction. (1995) (163)
- The renin-angiotensin system and its receptors. (1999) (163)
- Excitatory and modulatory effects of inflammatory cytokines and neurotrophins on mechanosensitive group IV muscle afferents in the rat (2005) (162)
- Role of the kidney in primary hypertension: a renal transplantation study in rats. (1990) (161)
- Evidence for the presence of enkephalins in the heart. (1983) (153)
- Persistent Tissue Converting Enzyme Inhibition Following Chronic Treatment with Hoe498 and MK421 in Spontaneously Hypertensive Rats (1985) (152)
- PPARgamma-activating angiotensin type-1 receptor blockers induce adiponectin. (2005) (151)
- Central blood pressure effects of substance P and angiotensin II: role of the sympathetic nervous system and vasopressin. (1981) (151)
- High prevalence and poor control of hypertension in primary care: cross-sectional study (2004) (148)
- Is Tissue Converting Enzyme Inhibition a Determinant of the Antihypertensive Efficacy of Converting Enzyme Inhibitors? Studies with the Two Different Compounds, Hoe498 and MK421, in Spontaneously Hypertensive Rats (1984) (148)
- RAS blockade with ARB and ACE inhibitors: current perspective on rationale and patient selection (2008) (146)
- The angiotensin type 2 receptor: variations on an enigmatic theme. (1999) (142)
- Brain converting enzyme inhibition: a possible mechanism for the antihypertensive action of captopril in spontaneously hypertensive rats. (1981) (140)
- Angiotensin II accelerates functional recovery in the rat sciatic nerve in vivo: role of the AT2 receptor and the transcription factor NF‐κB (2003) (137)
- Pathophysiologic and Therapeutic Importance of Tissue ACE: A Consensus Report (2002) (134)
- Atrial natriuretic peptide: a new factor in blood pressure control. (1987) (133)
- AT1 receptor antagonist telmisartan administered peripherally inhibits central responses to angiotensin II in conscious rats. (2001) (130)
- Regulation of Transport of the Angiotensin AT2 Receptor by a Novel Membrane-Associated Golgi Protein (2004) (129)
- Sciatic nerve transection evokes lasting up-regulation of angiotensin AT2 and AT1 receptor mRNA in adult rat dorsal root ganglia and sciatic nerves. (1998) (129)
- Spectrum analysis of sympathetic nerve activity and blood pressure in conscious rats. (1992) (126)
- Effects of lesions in the paraventricular nucleus of the hypothalamus on vasopressin and oxytocin contents in brainstem and spinal cord of rat (1983) (125)
- Acidic pH and capsaicin activate mechanosensitive group IV muscle receptors in the rat (2004) (124)
- Components of the renin-angiotensin system in the cerebrospinal fluid of rats and dogs with special consideration of the origin and the fate of angiotensin II. (1980) (122)
- Effect of early onset angiotensin converting enzyme inhibition on myocardial capillaries. (1992) (121)
- Involvement of adrenergic and angiotensinergic receptors in the paraventricular nucleus in the angiotensin II-induced vasopressin release. (1992) (121)
- Angiotensin II-induced vasopressin release is mediated through alpha-1 adrenoceptors and angiotensin II AT1 receptors in the supraoptic nucleus. (1993) (121)
- Blockade of bradykinin B2 receptors prevents the increase in capillary density induced by chronic angiotensin-converting enzyme inhibitor treatment in stroke-prone spontaneously hypertensive rats. (1997) (120)
- Novel therapeutic targets for hypertension (2010) (116)
- Chronic kinin receptor blockade attenuates the antihypertensive effect of ramipril. (1992) (116)
- Distribution of angiotensin II receptor subtypes in rat brain nuclei (1991) (114)
- The β-lactam antibiotic, ceftriaxone, dramatically improves survival, increases glutamate uptake and induces neurotrophins in stroke (2008) (114)
- Biglycan Is Required for Adaptive Remodeling After Myocardial Infarction (2008) (112)
- Angiotensin and its AT2 receptor: new insights into an old system (2001) (111)
- Non-peptide AT2-receptor agonists. (2011) (110)
- Angiotensin‐Induced Hypertension in the Rat Sympathetic Nerve Activity and Prostaglandins (1989) (110)
- Chronic pretreatment with candesartan improves recovery from focal cerebral ischaemia in rats (2003) (110)
- AT2 Receptor and Tissue Injury: Therapeutic Implications (2014) (109)
- Effects of converting enzyme inhibitors: ramipril and enalapril on peptide action and sympathetic neurotransmission in the isolated heart. (1985) (107)
- Differential Effects of Central Angiotensin II and Substance P on Sympathetic Nerve Activity in Conscious Rats Implications for Cardiovascular Adaptation to Behavioral Responses (1985) (106)
- Angiotensin peptides and inducible transcription factors (1999) (104)
- Physiological and pharmacological implications of AT1 versus AT2 receptors. (1998) (103)
- Brain angiotensin: on the way to becoming a well-studied neuropeptide system. (1984) (100)
- Angiotensin II evokes noradrenaline release from the paraventricular nucleus in conscious rats (1992) (100)
- Cardiac and vascular effects of long-term losartan treatment in stroke-prone spontaneously hypertensive rats. (1996) (99)
- Therapeutic perspectives in hypertension: novel means for renin–angiotensin–aldosterone system modulation and emerging device-based approaches (2011) (98)
- Prorenin engages the (pro)renin receptor like renin and both ligand activities are unopposed by aliskiren (2008) (98)
- Angiotensin receptor subtypes in the brain. (1992) (97)
- The past, present and future of angiotensin II type 2 receptor stimulation (2010) (96)
- Recognition and management of overweight and obesity in primary care in Germany (2004) (96)
- Direct Angiotensin II Type 2 Receptor Stimulation in N&ohgr;-Nitro-L-Arginine-Methyl Ester–Induced Hypertension: The Effect on Pulse Wave Velocity and Aortic Remodeling (2012) (96)
- Regulation of Peroxisome Proliferator–Activated Receptor &ggr; Activity by Losartan Metabolites (2006) (96)
- Sex-Specific Influence of Angiotensin Type 2 Receptor Stimulation on Renal Function: A Novel Therapeutic Target for Hypertension (2012) (95)
- Angiotensin-Converting Enzyme Inhibition in Infarct-Induced Heart Failure in Rats: Bradykinin Versus Angiotensin II (1994) (94)
- Direct Stimulation of Angiotensin II Type 2 Receptor Enhances Spatial Memory (2012) (94)
- Central tachykinins: mediators of defence reaction and stress reactions. (1995) (94)
- The Renin-Angiotensin-System in the Brain (1982) (93)
- Angiotensin II and NGF differentially influence microtubule proteins in PC12W cells: role of the AT2 receptor. (1998) (93)
- Effects of systemic treatment with irbesartan and losartan on central responses to angiotensin II in conscious, normotensive rats. (1999) (93)
- Patterns of antihypertensive drug utilization in primary care (2004) (92)
- Expression of angiotensin AT(1) and AT(2) receptors in adult rat cardiomyocytes after myocardial infarction. A single-cell reverse transcriptase-polymerase chain reaction study. (2000) (92)
- Optimal Treatment of Obesity-Related Hypertension: The Hypertension-Obesity-Sibutramine (HOS) Study (2007) (92)
- May Measurement Month 2019 (2019) (92)
- Angiotensin type 2 receptor (AT2R) and receptor Mas: a complex liaison. (2015) (90)
- AT2 receptor agonists: hypertension and beyond (2012) (89)
- Release and regulation of atrial natriuretic peptide (ANP). (1987) (88)
- Does low frequency power of arterial blood pressure reflect sympathetic tone? (1995) (88)
- Identification of Noncytotoxic and IL-10–Producing CD8+AT2R+ T Cell Population in Response to Ischemic Heart Injury (2010) (88)
- Tissue Renin-Angiotensin Systems: Focus on the Heart (1987) (87)
- Irbesartan for the treatment of hypertension in patients with the metabolic syndrome: A sub analysis of the Treat to Target post authorization survey. Prospective observational, two armed study in 14,200 patients (2007) (86)
- Substance P Induces a Cardiovascular Defense Reaction in the Rat: Pharmacological Characterization (1988) (86)
- Angiotensin receptor blockers: Therapeutic targets and cardiovascular protection (2005) (86)
- Free and conjugated plasma and urinary dopamine in human hypertension. (1979) (85)
- AT2 receptors in cardiovascular and renal diseases (2017) (85)
- The evolving story of the RAAS in hypertension, diabetes and CV disease – moving from macrovascular to microvascular targets (2009) (85)
- The role of the renin-angiotensin-aldosterone system in heart failure (2004) (85)
- Angiotensin as neuromodulator/neurotransmitter in central control of body fluid and electrolyte homeostasis. (1995) (84)
- Endogenous tissue renin-angiotensin systems. From molecular biology to therapy. (1988) (84)
- Candesartan but not ramipril pretreatment improves outcome after stroke and stimulates neurotrophin BNDF/TrkB system in rats (2008) (83)
- Receptors and their classification: focus on angiotensin II and the AT2 receptor (1998) (83)
- Tissue-Specific Expression of a Rat Renin Transcript Lacking the Coding Sequence for the Prefragment and Its Stimulation by Myocardial Infarction. (2000) (82)
- Endothelial Dysfunction Plays a Key Role in Increasing Cardiovascular Risk in Type 2 Diabetes: The Hoorn Study (2014) (82)
- AT2-receptor stimulation enhances axonal plasticity after spinal cord injury by upregulating BDNF expression (2013) (81)
- Angiotensin II receptor blockade and end-organ protection: pharmacological rationale and evidence. (1998) (80)
- Role of brain angiotensin in cardiovascular regulation. (1992) (79)
- Modulation of autonomic nervous system adjustments to heat stress by central ANG II receptor antagonism. (1994) (78)
- Differential expression of angiotensin receptors in human cutaneous wound healing (2005) (78)
- Antihypertensive Action of the Converting Enzyme Inhibitor Perindopril (S9490-3) in Spontaneously Hypertensive Rats: Comparison with Enalapril (MK421) and Ramipril (HOE498) (1986) (77)
- Atriopeptin III kinetics and pharmacodynamics in normal and anephric rats. (1986) (76)
- AT2 receptor stimulation induces generation of ceramides in PC12W cells (1999) (76)
- Antihypertensive Effect of the GABA Receptor Agonist Muscimol in Spontaneously Hypertensive Rats: Role of the Sympathoadrenal Axis (1984) (76)
- Effects of angiotensin-converting enzyme inhibition and angiotensin II AT1 receptor antagonism on cardiac parameters in left ventricular hypertrophy. (1997) (76)
- Adenosine triphosphate as a stimulant for nociceptive and non-nociceptive muscle group IV receptors in the rat (2003) (75)
- Effect of tachykinin receptor inhibition in the brain on cardiovascular and behavioral responses to stress. (1997) (75)
- Liver-Specific Peroxisome Proliferator–Activated Receptor α Target Gene Regulation by the Angiotensin Type 1 Receptor Blocker Telmisartan (2008) (74)
- Systolic Blood Pressure Variation and Mean Heart Rate Is Associated With Cognitive Dysfunction in Patients With High Cardiovascular Risk (2015) (74)
- Evidence for Heterodimerization and Functional Interaction of the Angiotensin Type 2 Receptor and the Receptor MAS (2017) (74)
- Hypertension transmitted by kidneys from stroke-prone spontaneously hypertensive rats. (1989) (74)
- The phorbol ester induced atrial natriuretic peptide secretion is stimulated by forskolin and bay K8644 and inhibited by 8-bromo-cyclicGMP (1986) (73)
- Protective arms of the renin–angiotensin‐system in neurological disease (2013) (73)
- The renin-angiotensin system in the brain: possible therapeutic implications for AT1-receptor blockers (2002) (73)
- Angiotensin II induces a complex activation of transcription factors in the rat brain: expression of Fos, Jun and Krox proteins (1995) (72)
- Effects of [D‐Ala2]‐Methionine‐Enkephalin on Blood Pressure, Heart Rate, and Baroreceptor Reflex Sensitivity in Conscious Cats (1981) (72)
- Long-term low-dose angiotensin converting enzyme inhibitor treatment increases vascular cyclic guanosine 3',5'-monophosphate. (1993) (71)
- Tissue renin-angiotensin systems in the heart and vasculature: possible involvement in the cardiovascular actions of converting enzyme inhibitors. (1990) (71)
- Minireview: The Brain Renin Angiotensin System 1982 (1982) (71)
- Angiotensin AT(2) receptor stimulates ERK1 and ERK2 in quiescent but inhibits ERK in NGF-stimulated PC12W cells. (2000) (70)
- Significance of angiotensin type 1 receptor blockade: why are angiotensin II receptor blockers different? (1999) (69)
- Selective activation of angiotensin AT2 receptors attenuates progression of pulmonary hypertension and inhibits cardiopulmonary fibrosis (2015) (69)
- Cardiac c‐kit+AT2+ Cell Population is Increased in Response to Ischemic Injury and Supports Cardiomyocyte Performance (2009) (69)
- The cardiovascular effects of oxytocin in conscious male rats. (1985) (68)
- Converting-enzyme in the choroid plexus, brain, and kidney: Immunocytochemical and biochemical studies in rats (1981) (67)
- Sex differences in physiological cardiac hypertrophy are associated with exercise-mediated changes in energy substrate availability. (2011) (67)
- Angiotensin Type 2 Receptor Stimulation Ameliorates Left Ventricular Fibrosis and Dysfunction via Regulation of Tissue Inhibitor of Matrix Metalloproteinase 1/Matrix Metalloproteinase 9 Axis and Transforming Growth Factor &bgr;1 in the Rat Heart (2014) (67)
- Angiotensin stimulates oxytocin release. (1981) (67)
- HOE 140, a new highly potent and long-acting bradykinin antagonist in conscious rats. (1991) (67)
- Growth or antigrowth: angiotensin and the endothelium (1995) (67)
- Inhibition of tissue angiotensin converting enzyme activity prevents malignant hypertension in TGR(mREN2)27 (1998) (66)
- The tissue renin-angiotensin systems: focus on brain angiotensin, adrenal gland and arterial wall. (1983) (66)
- Sensitization of rat dorsal horn neurons by NGF-induced subthreshold potentials and low-frequency activation. A study employing intracellular recordings in vivo (2007) (65)
- Angiotensin receptors in the brain. (1995) (65)
- Converting enzyme inhibitors in cardiovascular therapy: current status and future potential. (1994) (65)
- Selective activation of the converting enzyme inhibitor MK 421 and comparison of its active diacid form with captopril in different tissues of the rat. (1982) (65)
- Neurohormonal modulation in cardiovascular disease. (2000) (64)
- Angiotensin AT1 receptor-mediated vasopressin release and drinking are potentiated by an AT2 receptor antagonist. (1995) (64)
- Gabaergic stimulation inhibits central actions of angiotensin II: pressor responses, drinking and release of vasopressin. (1983) (64)
- Angiotensin type 2 receptors: blood pressure regulation and end organ damage. (2015) (63)
- Combined high-performance liquid chromatography-radioimmunoassay for the characterization and quantitative measurement of neuropeptides. (1984) (63)
- Impact of AT2-receptor stimulation on vascular biology, kidney function, and blood pressure (2013) (62)
- Differential effects of angiotensin AT1 and AT2 receptors on the expression, translation and function of the Na+-H+ exchanger and Na+-HCO3- symporter in the rat heart after myocardial infarction. (2001) (62)
- Transcriptional and translational regulation of calpain in the rat heart after myocardial infarction – effects of AT1 and AT2 receptor antagonists and ACE inhibitor (2001) (62)
- Effect of repetitive icv injections of ANG II on c-Fos and AT(1)-receptor expression in the rat brain. (2001) (62)
- Endothelial dysfunction and its role in diabetic vascular disease. (2006) (61)
- Angiotensin receptor blockers and cerebral protection in stroke (2006) (61)
- Cannabinoid receptor 1 inhibition improves cardiac function and remodelling after myocardial infarction and in experimental metabolic syndrome (2013) (61)
- Effects of losartan on haemodynamic parameters and angiotensin receptor mRNA levels in rat heart after myocardial infarction (2000) (61)
- Catecholamine excretion in "idiopathic" edema: decreased dopamine excretion, a pathogenic factor? (1977) (60)
- Tissue converting enzyme and cardiovascular actions of converting enzyme inhibitors. (1986) (60)
- Effect of sodium chloride and sodium bicarbonate on blood pressure in stroke-prone spontaneously hypertensive rats. (1988) (60)
- The angiotensin type 2 receptor agonist Compound 21 elicits cerebroprotection in endothelin-1 induced ischemic stroke (2014) (60)
- Plasma atrial natriuretic peptide values in cardiac disease. (1986) (60)
- Compound 21, the first orally active, selective agonist of the angiotensin type 2 receptor (AT2): implications for AT2 receptor research and therapeutic potential (2010) (59)
- Angiotensin II receptor blockade and end-organ protection. (1999) (58)
- PPARgamma activation attenuates T-lymphocyte-dependent inflammation of adipose tissue and development of insulin resistance in obese mice (2010) (58)
- The angiotensin AT2 receptor down-regulates neurofilament M in PC12W cells (1997) (57)
- Upregulation of osteopontin expression in renal cortex of streptozotocin-induced diabetic rats is mediated by bradykinin. (1998) (57)
- Transition from atherosclerosis to aortic aneurysm in humans coincides with an increased expression of RAS components. (2009) (57)
- Converting enzyme inhibition in kinin-deficient brown Norway rats. (1990) (57)
- Effects of orally applied candesartan cilexetil on central responses to angiotensin II in conscious rats (2002) (56)
- Rationale for double renin-angiotensin-aldosterone system blockade. (2007) (56)
- Effects of nonpersistence with medication on outcomes in high-risk patients with cardiovascular disease. (2013) (56)
- Measurement and characterization of angiotensin peptides in plasma. (1988) (56)
- Activity profile of calpains I and II in chronically infarcted rat myocardium – influence of the calpain inhibitor CAL 9961 (2002) (56)
- Tachykinin receptor inhibition and c-Fos expression in the rat brain following formalin-induced pain (1999) (55)
- The ongoing telmisartan alone and in combination with ramipril global endpoint trial program. (2003) (55)
- Vasopressin in brain of spontaneously hypertensive rats. (1982) (55)
- Opioid peptides and blood pressure regulation. (1982) (53)
- Telmisartan prevents aneurysm progression in the rat by inhibiting proteolysis, apoptosis and inflammation (2008) (53)
- Key advances in antihypertensive treatment (2012) (53)
- Alpha atrial natriuretic peptide concentrations in plasma of children with congenital heart and pulmonary diseases. (1985) (53)
- Significance of timing of angiotensin AT1 receptor blockade in rats with myocardial infarction-induced heart failure. (2001) (53)
- Dopamine-sodium relationship: is dopamine a part of the endogenous natriuretic system? (1978) (53)
- AT2R Agonist, Compound 21, Is Reno-Protective Against Type 1 Diabetic Nephropathy (2015) (52)
- Release of angiostensin in the paraventricular nucleus in response to hyperosmotic stimulation in conscious rats: a microdialysis study (1994) (52)
- The renin-angiotensin system in the brain: possible therapeutic implications for AT(1)-receptor blockers. (2002) (51)
- The role of angiotensin receptors in cardiovascular diseases. (1997) (50)
- Angiotensin receptors. (1996) (50)
- Catecholamine turnover changes in hypothalamus and dorsal midline area of the caudal medulla oblongata of spontaneously hypertensive rats (1979) (50)
- Hypertension in rats induced by renal grafts from renovascular hypertensive donors. (1990) (49)
- Angiotensin II-induced noradrenaline release from anterior hypothalamus in conscious rats: a brain microdialysis study (1991) (49)
- Calcium Channel Blockade Limits Cardiac Remodeling and Improves Cardiac Function in Myocardial Infarction-Induced Heart Failure in Rats (2001) (49)
- Angiotensin Type 2 Receptor Stimulation Increases Renal Function in Female, but Not Male, Spontaneously Hypertensive Rats (2014) (48)
- Distribution and metabolism of angiotensin I and II in the blood vessel wall. (1992) (48)
- Angiotensin biosynthesis and concentrations in brain of normotensive and hypertensive rats. (1984) (48)
- Angiotensin converting enzyme inhibitors, left ventricular hypertrophy and fibrosis (1995) (47)
- Role of Bradykinin in Chronic Antihypertensive Actions of Rarnipril in Different Hypertension Models (1992) (47)
- Renal handling of free and conjugated catecholamines following surgical stress in the dog. (1978) (47)
- Review: The renin-angiotensin system in the brain: an update (2001) (47)
- Reduced content of vasopressin in the brain of spontaneously hypertensive as compared to normotensive rats (1981) (46)
- Prevention of diabetic nephropathy by compound 21, selective agonist of angiotensin type 2 receptors, in Zucker diabetic fatty rats. (2014) (46)
- The Renin–Angiotensin System in the Heart and Vascular Wall: New Therapeutic Aspects (1994) (46)
- Natriuretic action of central angiotensin II in conscious rats (1989) (46)
- Physiologic and pharmacologic implications of AT1 versus AT2 receptors. (1996) (46)
- Central peptidergic stimulation in blood pressure control: role of enkephalins in rats. (1981) (45)
- Antihypertensive and cardioprotective effects after angiotensin-converting enzyme inhibition: role of kinins. (1997) (45)
- Beyond blood pressure: new roles for angiotensin II (1999) (45)
- The Selective Angiotensin II Type 2 Receptor Agonist, Compound 21, Attenuates the Progression of Lung Fibrosis and Pulmonary Hypertension in an Experimental Model of Bleomycin-Induced Lung Injury (2018) (45)
- Differential Modulation of the Baroreceptor Reflex by Brain and Plasma Vasopressin (1986) (45)
- Angiotensin II induces peroxisome proliferator‐activated receptor gamma in PC12W cells via angiotensin type 2 receptor activation (2005) (45)
- Cardioprotective effects of the Na(+)/H(+)-exchange inhibitor cariporide in infarct-induced heart failure. (2000) (45)
- Conjugated dopamine: peripheral origin, distribution, and response to acute stress in the dog. (1980) (45)
- Compound 21, a selective agonist of angiotensin AT2 receptors, prevents endothelial inflammation and leukocyte adhesion in vitro and in vivo (2016) (44)
- Adapter proteins and promoter regulation of the angiotensin AT2 receptor — implications for cardiac pathophysiology (2010) (44)
- Chronic Treatment With Losartan Results in Sufficient Serum Levels of the Metabolite EXP3179 for PPAR&ggr; Activation (2009) (44)
- Tissue Renin—Angiotensin Systems: Fact or Fiction? (1991) (44)
- Effect of hemorrhagic shock on the concomitant release of endorphin and enkephalin-like peptides from the pituitary and adrenal gland in the dog. (1982) (43)
- Functional, biochemical, and molecular investigations of renal kallikrein-kinin system in diabetic rats. (1999) (43)
- Baroreceptor reflex effect on sympathetic nerve activity in stroke-prone spontaneously hypertensive rats. (1986) (43)
- Atrial natriuretic factor determinations and chronic sodium homeostasis. (1986) (43)
- Aldosterone synthase inhibitors in cardiovascular and renal diseases. (2014) (43)
- Osmotically induced natriuresis and blood pressure response involves angiotensin AT1 receptors in the subfornical organ (1995) (42)
- The CD4+AT2R+ T cell subpopulation improves post-infarction remodelling and restores cardiac function (2015) (42)
- The angiotensin AT2 receptor in inflammation. (2010) (42)
- Drug Interactions with Angiotensin Receptor Blockers: A Comparison with Other Antihypertensives (2003) (42)
- Use of selective antagonists to dissociate the central cardiovascular and behavioural effects of tachykinins on NK1 and NK2 receptors in the rat (1992) (42)
- The angiotensin AT2 receptor in left ventricular hypertrophy (2010) (41)
- Inhibiting angiotensin receptors in the brain: possible therapeutic implications (2003) (41)
- Are angiotensin receptor blockers neuroprotective? (2004) (41)
- Contribution of bradykinin and nitric oxide to AT2 receptor‐mediated differentiation in PC12 W cells (2003) (41)
- Vascular protection in diabetes: a pharmacological view of angiotensin II type 1 receptor blockers (2005) (40)
- A block of spinal nitric oxide synthesis leads to increased background activity predominantly in nociceptive dorsal horn neurones in the rat (2000) (40)
- Genetic kininogen deficiency contributes to aortic aneurysm formation but not to atherosclerosis. (2004) (40)
- Signal transduction of the (pro)renin receptor as a novel therapeutic target for preventing end-organ damage (2010) (40)
- Impact of the AT2 Receptor Agonist C21 on Blood Pressure and Beyond (2012) (40)
- Comparison between single and combined treatment with candesartan and pioglitazone following transient focal ischemia in rat brain (2008) (40)
- Blood pressure lowering and renin-angiotensin system blockade (2003) (40)
- Effect of converting enzyme inhibitors on tissue converting enzyme and angiotensin II: therapeutic implications. (1987) (39)
- The role of the renin-angiotensin-aldosterone system in heart failure (2004) (39)
- Definite Evidence for the Presence of [Ile5]-Angiotensin I and [Ile5]-Angiotensin II in the Brain of Rats (1982) (39)
- Angiotensin AT2-receptor stimulation improves survival and neurological outcome after experimental stroke in mice (2016) (39)
- Angiotensin II receptor pharmacology and AT1-receptor blockers (1999) (39)
- Characterization of New PPARγ Agonists: Analysis of Telmisartan’s Structural Components (2009) (39)
- Pathophysiological activity in rat dorsal horn neurones in segments rostral to a chronic spinal cord injury (2003) (38)
- Role of kinins and substance p in the central blood pressure regulation of normotensive and spontaneously hypertensive rats (1981) (38)
- Direct angiotensin type 2 receptor (AT2R) stimulation attenuates T-cell and microglia activation and prevents demyelination in experimental autoimmune encephalomyelitis in mice. (2015) (38)
- Identification of the central tachykinin receptor subclass involved in substance P-induced cardiovascular and behavioral responses in conscious rats. (1992) (37)
- Over-expression of angiotensin converting enzyme-1 augments cardiac hypertrophy in transgenic rats. (2004) (37)
- Differential regulation of thrombospondin-1 and fibronectin by angiotensin II receptor subtypes in cultured endothelial cells. (2001) (37)
- Localization of the substance P-induced cardiovascular responses in the rat hypothalamus (1991) (37)
- The possible role of the NO-cGMP pathway in nociception: Different spinal and supraspinal action of enzyme blockers on rat dorsal horn neurones (2005) (36)
- The angiotensin II type 2 receptor agonist Compound 21 is protective in experimental diabetes-associated atherosclerosis (2016) (35)
- Development of Genetic Hypertension: Is There a “Critical Phase”? (1990) (35)
- Plasma-converting enzyme activity does not reflect effectiveness of oral treatment with captopril. (1981) (35)
- New therapeutic pathways in the RAS (2012) (35)
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- Abstract 3608: High Mobility Group A1 Protein - A New Regulator for Peroxisome Proliferator-Activated Receptor Gamma Transcriptional Repression in Human Aortic Smooth Muscle Cells (2008) (0)
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- AT1 RECEPTOR BLOCKADE AND AT2 RECEPTOR STIMULATION EFFECT ON THE RAS PEPTIDE LEVELS IN THE PREVENTION AND TREATMENT OF EXPERIMENTAL AUTOIMMUNE MYOCARDITIS (EAM) IN MALE LEW (2018) (0)
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- Identification and characterization of the CD4+AT2R+ T cell subpo-pulation in rats and humans. (2010) (0)
- Time dependent apoptotic development in the acute phase of myocardial infarction in rats (2000) (0)
- 9D.04 THE NON-PEPTIDE AT2-RECEPTOR AGONIST COMPOUND 21 AMELIORATES HYPERTROPHY AND FIBROSIS IN UREMIA-ASSOCIATED CARDIOMYOPATHY (2010) (0)
- MECHANISMS OF AORTIC ANEURYSM FORMATION BY KININOGEN DEFICIENCY: 4D.8 (2004) (0)
- Identification of a non-cytotoxic and IL-10-producing CD 8 + AT 2 R + T lymphocyte population in response to ischemic heart injury (2011) (0)
- CIRCULATING Na+/K+‐ATPase INHIBITORS: EFFECTS OF NEUROPEPTIDES, VOLUME EXPANSION AND SALT LOADING IN CONSCIOUS RATS (1997) (0)
- Effects of the calcium channel antagonist mibefradil on haemodynamic 2 1 parameters and myocardial Ca-handling in infarct-induced heart failure in rats (1999) (0)
- CHANGES IN BAROREFLEX CONTROL OF HEART RATE PRODUCED BY CENTRAL INFUSION OF THE NOVEL NONPEPTIDE AT2 RECEPTOR AGONIST, COMPOUND 21: 6D.02 (2011) (0)
- Abstract 464: Molecular and Functional Interaction of the Angiotensin AT2-Receptor and the Receptor MAS (2013) (0)
- Use of antigonists of the angiotensin ii receptor, in particular of telmisartane, to increase the insulin sensitivity. (2004) (0)
- 203 Endothelial proliferation is inhibited by angiotensin peptides (1993) (0)
- 14th Annual Meeting on Surgical Research 14. Chirurgische Forschungstage (2010) (0)
- Abstract 483: Mas/AT2 Receptor Deficient Mice Present A Pronounced Endothelial Dysfunction That Is Exclusively Mas-Related (2014) (0)
- THE NON-PEPTIDE AT2-RECEPTOR AGONIST COMPOUND 21 AMELIORATES HYPERTROPHY AND FIBROSIS IN UREMIA-ASSOCIATED CARDIOMYOPATHY: 9D.04 (2010) (0)
- 200 Mechanisms involved in chronic antihypertensive action of cicletaninine in spontaneously hypertensive rats (1993) (0)
- AT2 function and target genes (2004) (0)
- 136. Atrial natriuretic factor and central osmoregulation (1991) (0)
- The Renin Angiotensin System and the Metabolic Syndrome (2004) (0)
- C 21 preserves endothelial function in the thoracic aorta from DIO mice : role for 1 AT 2 , Mas and B 2 receptors 2 (2021) (0)
- Angiotensin AT2 receptor agonist, compound 21, maintains vascular integrity and prevents abdominal aortic aneurysm progression in the rat (2017) (0)
- [Cost benefit analysis of hypertension treatment]. (1989) (0)
- The Role of Arginine-Vasopressin in Blood Pressure Control (1983) (0)
- AT 2 R stimulation with C 21 prevents arterial stiffening and endothelial dysfunction in 2 the abdominal aorta from mice fed a high-fat diet 3 (2021) (0)
- Inhibition de l'enzyme de conversion et cardioprotection : rôle des brakykinines (1992) (0)
- [Dopamine in the kidney: a further natriuretic hormone?]. (1985) (0)
- Morphine inhibits cardiovascular and behavioral responses evoked by centrally administered substance P (SP) in conscious rats (1992) (0)
- Use of the angiotensin II receptor antagonists for increasing insulin sensitivity (2004) (0)
- Use of the angiotensin II receptor antagonists, in particular of telmisartan, for increasing insulin sensitivity (2004) (0)
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