Thomas Weber
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Thomas Webercomputer-science Degrees
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Computer Science
Thomas Weber's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
- Bachelors Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)Thomas Weber's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- SNAREpins: Minimal Machinery for Membrane Fusion (1998) (2435)
- Reconstitution of Ca2+-Regulated Membrane Fusion by Synaptotagmin and SNAREs (2004) (376)
- Cathepsin D targeted by acid sphingomyelinase‐derived ceramide (1999) (365)
- Close is not enough: SNARE-dependent membrane fusion requires an active mechanism that transduces force to membrane anchors. (2000) (309)
- Rapid and efficient fusion of phospholipid vesicles by the alpha-helical core of a SNARE complex in the absence of an N-terminal regulatory domain. (1999) (266)
- Functional architecture of an intracellular membrane t-SNARE (2000) (231)
- Intracellular transport of recombinant adeno-associated virus vectors (2012) (219)
- Regulation of membrane fusion by the membrane-proximal coil of the t-SNARE during zippering of SNAREpins (2002) (218)
- Pre-existing anti-adeno-associated virus antibodies as a challenge in AAV gene therapy. (2013) (216)
- Content mixing and membrane integrity during membrane fusion driven by pairing of isolated v-SNAREs and t-SNAREs. (1999) (194)
- The length of the flexible SNAREpin juxtamembrane region is a critical determinant of SNARE-dependent fusion. (1999) (166)
- Adeno-associated virus 2 infection requires endocytosis through the CLIC/GEEC pathway. (2011) (160)
- Neutralizing antibodies against AAV serotypes 1, 2, 6, and 9 in sera of commonly used animal models. (2012) (141)
- Ceramide as an activator lipid of cathepsin D. (2000) (124)
- Snarepins Are Functionally Resistant to Disruption by Nsf and αSNAP (2000) (120)
- Expressing Transgenes That Exceed the Packaging Capacity of Adeno-Associated Virus Capsids. (2016) (98)
- Evidence for H(+)-induced insertion of influenza hemagglutinin HA2 N-terminal segment into viral membrane. (1994) (95)
- Altering AAV tropism with mosaic viral capsids. (2005) (78)
- The Myristoyl Moiety of Myristoylated Alanine-rich C Kinase Substrate (MARCKS) and MARCKS-related Protein Is Embedded in the Membrane (*) (1995) (77)
- Gene therapy for heart failure. (2012) (75)
- Identification of functional domains in the cytoskeletal protein talin. (1994) (74)
- N-Linked glycosylation of antibody fragments in Escherichia coli. (2011) (73)
- Syntaxin 5-Dependent Retrograde Transport to the trans-Golgi Network Is Required for Adeno-Associated Virus Transduction (2014) (63)
- Cardiac I-1c overexpression with reengineered AAV improves cardiac function in swine ischemic heart failure. (2014) (63)
- Liposome fusion assay to monitor intracellular membrane fusion machines. (2003) (57)
- Human Cardiac Gene Therapy (2018) (56)
- Near-perfect infectivity of wild-type AAV as benchmark for infectivity of recombinant AAV vectors (2010) (52)
- Anti-AAV Antibodies in AAV Gene Therapy: Current Challenges and Possible Solutions (2021) (51)
- Mutations in Human Parainfluenza Virus Type 3 Hemagglutinin-Neuraminidase Causing Increased Receptor Binding Activity and Resistance to the Transition State Sialic Acid Analog 4-GU-DANA (Zanamivir) (2003) (44)
- Effectiveness of gene delivery systems for pluripotent and differentiated cells (2015) (40)
- Cardiac gene therapy with adeno-associated virus-based vectors (2017) (39)
- Effect of inhibition of dynein function and microtubule-altering drugs on AAV2 transduction. (2007) (38)
- Alternatively Spliced Tissue Factor Promotes Plaque Angiogenesis Through the Activation of Hypoxia-Inducible Factor-1&agr; and Vascular Endothelial Growth Factor Signaling (2014) (35)
- Putative fusogenic activity of NSF is restricted to a lipid mixture whose coalescence is also triggered by other factors (2000) (34)
- Concomitant intravenous nitroglycerin with intracoronary delivery of AAV1.SERCA2a enhances gene transfer in porcine hearts. (2012) (34)
- Successful Transduction with AAV Vectors after Selective Depletion of Anti-AAV Antibodies by Immunoadsorption (2020) (33)
- Protein S Protects against Podocyte Injury in Diabetic Nephropathy. (2018) (30)
- Insertion of filamin into lipid membranes examined by calorimetry, the film balance technique, and lipid photolabeling. (1994) (30)
- Quantification of AAV particle titers by infrared fluorescence scanning of coomassie-stained sodium dodecyl sulfate-polyacrylamide gels. (2012) (28)
- Protein Phosphatase Inhibitor-1 Gene Therapy in a Swine Model of Nonischemic Heart Failure. (2017) (27)
- Identification of synapsin I peptides that insert into lipid membranes. (2001) (25)
- High capsid-genome correlation facilitates creation of AAV libraries for directed evolution. (2015) (24)
- Effect of Bortezomib on the Efficacy of AAV9.SERCA2a Treatment to Preserve Cardiac Function in a Rat Pressure-Overload Model of Heart Failure (2014) (23)
- Identification of synapsin I peptides that insert into lipid membranes (2001) (22)
- Intracellular trafficking of adeno-associated virus (AAV) vectors: challenges and future directions (2021) (20)
- Use of Adeno-Associated Virus Vector for Cardiac Gene Delivery in Large-Animal Surgical Models of Heart Failure. (2017) (19)
- A putative link between exocytosis and tumor development. (2002) (16)
- Regulation of the Methylation and Expression Levels of the BMPR2 Gene by SIN3a as a Novel Therapeutic Mechanism in Pulmonary Arterial Hypertension (2021) (16)
- Targeted Gene Delivery through the Respiratory System: Rationale for Intratracheal Gene Transfer (2019) (16)
- Gene therapy: charting a future course--summary of a National Institutes of Health Workshop, April 12, 2013. (2014) (13)
- pH-Dependent lytic peptides discovered by phage display. (2006) (12)
- Production and Characterization of Vectors Based on the Cardiotropic AAV Serotype 9. (2017) (10)
- Alternatively Spliced Tissue Factor Promotes Plaque Angiogenesis Through the Activation of HIF-1α and VEGF Signaling (2014) (9)
- Close Is Not Enough (2000) (9)
- Identification of intracellular ceramide target proteins by affinity chromatography and TID-ceramide photoaffinity labelling. (1999) (9)
- Loss of receptor regulation by a phospholipase D1 mutant unresponsive to protein kinase C (2000) (8)
- Effects of genetic transfection on calcium cycling pathways mediated by double-stranded adeno-associated virus in postinfarction remodeling. (2020) (8)
- Interaction of MARCKS, a major protein kinase C substrate, with the membrane (1995) (6)
- Gene Therapy for Heart Failure (2012) (6)
- Use of affinity chromatography and TID-ceramide photoaffinity labeling for detection of ceramide-binding proteins. (2000) (5)
- A Calsequestrin Cis-Regulatory Motif Coupled to a Cardiac Troponin T Promoter Improves Cardiac Adeno-Associated Virus Serotype 9 Transduction Specificity. (2018) (5)
- AAV Vectors for Efficient Gene Delivery to Rodent Hearts. (2019) (4)
- Do we need marker gene studies in humans to improve clinical AAV gene therapy? (2017) (4)
- Identification of Genes and Pathways Regulated by Lamin A in Heart (2020) (4)
- Novel Approaches to Deliver Molecular Therapeutics in Cardiac Disease Using Adeno-Associated Virus Vectors (2012) (3)
- Hydroxylation of N-acetylneuraminic Acid Influences the in vivo Tropism of N-linked Sialic Acid-Binding Adeno-Associated Viruses AAV1, AAV5, and AAV6 (2021) (1)
- The myristoyl moiety of MARCKS and MARCKS-related protein (MRP) is embedded in the membrane (1995) (1)
- Intratracheal Gene Delivery of SIN3A Inhibits Pulmonary Arterial Hypertension and Restores BMPR2 Expression (2020) (0)
- Gene Therapy for Cardiovascular Diseases (2016) (0)
- Correction: Intracellular trafficking of adeno-associated virus (AAV) vectors: challenges and future directions (2021) (0)
- Abstract 13932: Lung-targeted Sin3a Gene Therapy as a Promising Strategy to Restore Bmpr2 Expression in Pulmonary Arterial Hypertension (2020) (0)
- , Claudia and VEGF Signaling α HIF-1 Alternatively Spliced Tissue Factor Promotes Plaque Angiogenesis Through the Activation of (2014) (0)
- 3213 Unraveling the role of Phospholamban (PLN) in humans via the characterization of Induced Pluripotent Stem Cell (iPSC) Cardiomyocytes (CM) derived from carriers of a lethal PLN mutation (2019) (0)
- Cathepsin D targeted by acid sphingomyelinase‐derived ceramide (0)
- Selective Anti-AAV Antibody Depletion by Hemapheresis and Immunoadsorption. (2022) (0)
- Abstract 10253: Sin3a Gene Delivery Restores Bmpr2 Expression Through Foxk2 in Pulmonary Arterial Endothelial Cells and Inhibits Sugen/Hypoxia-Induced Pah (2021) (0)
- Abstract 18784: Lamin A/C Regulates Transcription Factor and Epigenetic Gene Networks in the Heart (2017) (0)
- Abstract 18340: Alternatively Spliced Tissue Factor Promotes Atherosclerosis by Increasing Foam Cell Formation via LOX-1 and SR-A1 up-regulation (2015) (0)
- Abstract 16942: Alternatively Spliced Tissue Factor promotes plaque progression, inflammation and angiogenesis in experimental atherosclerosis (2014) (0)
- Abstract 10248: Regulation of the Methylation and Expression Levels of the Bmpr2 Gene by Sin3a as a Novel Therapeutic Mechanism in Pulmonary Arterial Hypertension (2021) (0)
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Thomas Weber is affiliated with the following schools: