Thorsteinn Loftsson
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(Suggest an Edit or Addition)Thorsteinn Loftsson's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Pharmaceutical applications of cyclodextrins. 1. Drug solubilization and stabilization. (1996) (2001)
- Cyclodextrins as pharmaceutical solubilizers. (2007) (1612)
- Cyclodextrins and their pharmaceutical applications. (2007) (1150)
- Cyclodextrins in drug delivery (2005) (702)
- Pharmaceutical applications of cyclodextrins: basic science and product development (2010) (681)
- Studies of curcumin and curcuminoids. XXVII. Cyclodextrin complexation: solubility, chemical and photochemical stability. (2002) (653)
- Evaluation of cyclodextrin solubilization of drugs. (2005) (554)
- Cyclodextrins in topical drug formulations: theory and practice. (2001) (433)
- Cyclodextrins: structure, physicochemical properties and pharmaceutical applications. (2018) (416)
- Self-association of cyclodextrins and cyclodextrin complexes. (2004) (397)
- Cyclodextrins as functional excipients: methods to enhance complexation efficiency. (2012) (356)
- Solubility of Cyclodextrins and Drug/Cyclodextrin Complexes (2018) (307)
- Self-association and cyclodextrin solubilization of drugs. (2002) (267)
- Role of cyclodextrins in improving oral drug delivery (2004) (265)
- Effects of cyclodextrins on drug delivery through biological membranes. (2007) (264)
- Studies on curcumin and curcuminoids XXXI. Symmetric and asymmetric curcuminoids: stability, activity and complexation with cyclodextrin. (2007) (261)
- Self-assembled cyclodextrin aggregates and nanoparticles. (2010) (258)
- Pharmaceutical applications of cyclodextrins: effects on drug permeation through biological membranes (2011) (222)
- Cyclodextrins as permeation enhancers: some theoretical evaluations and in vitro testing. (1999) (199)
- The effect of water-soluble polymers on drug-cyclodextrin complexation (1994) (190)
- Soft antimicrobial agents: synthesis and activity of labile environmentally friendly long chain quaternary ammonium compounds. (2003) (190)
- Pharmaceutical applications of β-cyclodextrin (1999) (184)
- Cyclodextrin-based nanogels for pharmaceutical and biomedical applications. (2012) (159)
- The complexation efficiency (2007) (152)
- Cyclodextrins in eye drop formulations: enhanced topical delivery of corticosteroids to the eye. (2002) (150)
- Antibacterial activity of methylated chitosan and chitooligomer derivatives: Synthesis and structure activity relationships (2007) (149)
- The effect of water-soluble polymers on aqueous solubility of drugs (1996) (129)
- Comparative interaction of 2-hydroxypropyl-beta-cyclodextrin and sulfobutylether-beta-cyclodextrin with itraconazole: phase-solubility behavior and stabilization of supersaturated drug solutions. (2008) (121)
- The effect of water-soluble polymers on the aqueous solubility and complexing abilities of β-cyclodextrin (1998) (117)
- Cyclodextrins as solubilizers: formation of complex aggregates. (2010) (113)
- Cyclodextrin solubilization of benzodiazepines: formulation of midazolam nasal spray. (2001) (111)
- Effect of Cyclodextrins on Topical Drug Delivery to the Eye (1997) (109)
- Cyclodextrins and the Biopharmaceutics Classification System of Drugs (2002) (108)
- Cyclodextrin-Based Formulations: A Non-Invasive Platform for Targeted Drug Delivery. (2018) (108)
- Self-Assembly of Cyclodextrins and Their Complexes in Aqueous Solutions. (2016) (106)
- Dexamethasone-cyclodextrin-polymer co-complexes in aqueous eye drops. Aqueous humor pharmacokinetics in humans. (1996) (100)
- Methods to enhance the complexation efficiency of cyclodextrins (1999) (97)
- Cyclodextrin microparticles for drug delivery to the posterior segment of the eye: aqueous dexamethasone eye drops (2007) (96)
- Cyclodextrin complexation of NSAIDSs: physicochemical characteristics (1993) (96)
- Topical and systemic absorption in delivery of dexamethasone to the anterior and posterior segments of the eye. (2007) (93)
- Cyclodextrins and topical drug delivery to the anterior and posterior segments of the eye. (2017) (93)
- Synthesis and Characterization of Chitosan N-Betainates Having Various Degrees of Substitution (2004) (91)
- Investigation and physicochemical characterization of vinpocetine-sulfobutyl ether beta-cyclodextrin binary and ternary complexes. (2003) (91)
- Self Association and Cyclodextrin Solubilization of NSAIDs (2002) (91)
- A permeation method for detection of self-aggregation of doxorubicin in aqueous environment. (2013) (90)
- The effects of water-soluble polymers on cyclodextrins and cyclodextrin solubilization of drugs (2004) (89)
- Diffusion characteristics of vitreous humour and saline solution follow the Stokes Einstein equation (2009) (86)
- Topical dexamethasone-cyclodextrin microparticle eye drops for diabetic macular edema. (2011) (86)
- The effects of organic salts on the cyclodextrin solubilization of drugs. (2003) (83)
- CDs as solubilizers: effects of excipients and competing drugs. (2009) (82)
- Carvedilol: Solubilization and Cyclodextrin Complexation: A Technical Note (2008) (81)
- The effect of hydroxypropyl methylcellulose on the release of dexamethasone from aqueous 2-hydroxypropyl-β-cyclodextrin formulations (1994) (78)
- Cyclodextrins and drug permeability through semi-permeable cellophane membranes. (2002) (78)
- Co-Administration of a Water-Soluble Polymer Increases the Usefulness of Cyclodextrins in Solid Oral Dosage Forms (1998) (77)
- Cyclodextrin solubilization of the antibacterial agents triclosan and triclocarban: formation of aggregates and higher-order complexes. (2005) (75)
- Increasing the cyclodextrin complexation of drugs and drug biovailability through addition of water-soluble polymers. (1998) (73)
- Topical dexamethasone γ‐cyclodextrin nanoparticle eye drops increase visual acuity and decrease macular thickness in diabetic macular oedema (2015) (71)
- The effect of polyvinylpyrrolidone on cyclodextrin complexation of hydrocortisone and its diffusion through hairless mouse skin (1995) (71)
- Effects of cyclodextrins on the chemical stability of drugs. (2017) (69)
- Determination of aqueous solubility by heating and equilibration: A technical note (2006) (68)
- Stabilisation of ionic drugs through complexation with non-ionic and ionic cyclodextrins (1998) (67)
- Self-assembly of cyclodextrins: the effect of the guest molecule. (2011) (65)
- Topically effective ocular hypotensive acetazolamide and ethoxyzolamide formulations in rabbits (1994) (65)
- Pharmacokinetics of cyclodextrins and drugs after oral and parenteral administration of drug/cyclodextrin complexes (2016) (64)
- Studies of curcumin and curcuminoids. XXXVI. The stoichiometry and complexation constants of cyclodextrin complexes as determined by the phase-solubility method and UV–Vis titration (2010) (62)
- Effect of cyclodextrins and polymers on triclosan availability and substantivity in toothpastes in vivo. (1999) (62)
- Cyclodextrin formulation of dorzolamide and its distribution in the eye after topical administration. (2005) (62)
- Topical drug delivery to the eye: dorzolamide (2012) (62)
- Effect of the unstirred water layer on permeability enhancement by hydrophilic cyclodextrins. (2007) (61)
- Self-assembly of cyclodextrin complexes: aggregation of hydrocortisone/cyclodextrin complexes. (2011) (61)
- Soft antibacterial agents. (2003) (60)
- Cyclodextrin Solubilization of the Antibacterial Agents Triclosan and Triclocarban: Effect of Ionization and Polymers (2005) (60)
- Improved delivery through biological membranes. XXXL: Solubilization and stabilization of an estradiol chemical delivery system by modified beta-cyclodextrins. (1988) (60)
- Cyclodextrin solubilization of carbonic anhydrase inhibitor drugs: formulation of dorzolamide eye drop microparticle suspension. (2010) (59)
- Self‐association of cyclodextrins and cyclodextrin complexes in aqueous solutions (2019) (59)
- Topical drug delivery to the posterior segment of the eye: anatomical and physiological considerations. (2008) (57)
- Drug permeation through biomembranes: cyclodextrins and the unstirred water layer. (2012) (57)
- The effects of cyclodextrins on transdermal delivery of drugs (1991) (55)
- Assessment of mucoadhesion by a resonant mirror biosensor. (2006) (54)
- Dexamethasone eye drops containing γ-cyclodextrin-based nanogels. (2013) (54)
- The Influence of water-soluble polymers and pH on hydroxypropyl-β-cyclodextrin complexation of drugs (1996) (53)
- Investigation of drug-cyclodextrin complexes by a phase-distribution method: some theoretical and practical considerations. (2005) (52)
- Buccal absorption of ergotamine tartrate using the bioadhesive tablet system in guinea-pigs. (2002) (52)
- 2-hydroxypropyl-β-cyclodextrin in topical carbonic anhydrase inhibitor formulations (1994) (52)
- Drug solubilization by complexation. (2017) (52)
- Interactions between preservatives and 2-hydroxypropyl-β-cyclodextrin (1992) (51)
- Encapsulation of drug molecules into calix[n]arene nanobaskets. role of aminocalix[n]arenes in biopharmaceutical field. (2013) (51)
- The effect of polyvinylpyrrolidone and hydroxypropyl methylcellulose on HPβCD complexation of hydrocortisone and its permeability through hairless mouse skin (1994) (50)
- Metabolism, Distribution, and Transdermal Permeation of a Soft Corticosteroid, Loteprednol Etabonate (1992) (49)
- Effect of various cyclodextrins on solution stability and dissolution rate of doxorubicin hydrochloride (1992) (48)
- Influence of aqueous diffusion layer on passive drug diffusion from aqueous cyclodextrin solutions through biological membranes. (2006) (48)
- Comparison of topical 0.7% dexamethasone–cyclodextrin with 0.1% dexamethasone sodium phosphate for postcataract inflammation (2006) (47)
- The Stokes-Einstein equation and the physiological effects of vitreous surgery. (2006) (46)
- Development and evaluation of an artificial membrane for determination of drug availability. (2006) (46)
- The effects of 2-hydroxypropyl-β-cyclodextrin on the solubility and stability of chlorambucil and melphalan in aqueous solution (1989) (45)
- Cross-linked hydroxypropyl-β-cyclodextrin and γ-cyclodextrin nanogels for drug delivery: Physicochemical and loading/release properties (2012) (45)
- Intranasal administration of midazolam in a cyclodextrin based formulation: bioavailability and clinical evaluation in humans. (2001) (44)
- Effect of self-aggregation of γ-cyclodextrin on drug solubilization (2010) (44)
- Preparation of solid drug/cyclodextrin complexes of acidic and basic drugs. (2004) (44)
- Cyclodextrins in ocular drug delivery: theoretical basis with dexamethasone as a sample drug (2007) (44)
- The use of chemically modified cyclodextrins in the development of formulations for chemical delivery systems. (2002) (43)
- Drug delivery to retinal photoreceptors (2019) (42)
- Cyclodextrins: new drug delivery systems in dermatology. (1998) (42)
- Evaluation of a cationic calix[4]arene: Solubilization and self-aggregation ability. (2010) (41)
- Intranasal midazolam: a comparison of two delivery devices in human volunteers (2006) (41)
- Electroblowing and electrospinning of fibrous diclofenac sodium-cyclodextrin complex-based reconstitution injection (2015) (41)
- Drug/cyclodextrin: beyond inclusion complexation (2011) (40)
- Topical drug delivery to the posterior segment of the eye: Dexamethasone concentrations in various eye tissues after topical administration for up to 15 days to rabbits (2018) (39)
- Determination of aqueous solubility by heating and equilibration: A technical note. (2006) (39)
- The Influence of 2-Hydroxypropyl-β-Cyclodextrin on Diffusion Rates and Transdermal Delivery of Hydrocortisone (1994) (38)
- Improved delivery through biological membranes XD: Percutaneous absorption and metabolism of methylsulfinylmethyl 2-acetoxybenzoate and related aspirin prodrugs. (1981) (38)
- Self-assembly of cyclodextrin complexes: effect of temperature, agitation and media composition on aggregation. (2011) (37)
- Formulation and testing of methazolamide cyclodextrin eye drop solutions (1997) (37)
- Aqueous hydrocortisone mouthwash solution: clinical evaluation. (1998) (37)
- Cyclodextrins in parenteral formulations. (2020) (36)
- Excipient pharmacokinetics and profiling. (2015) (36)
- Potentiation of anticancer effects of microencapsulated carboplatin by hydroxypropyl α-cyclodextrin (1996) (36)
- yCD/HPyCD mixtures as solubilizer: solid-state characterization and sample dexamethasone eye drop suspension. (2010) (35)
- Kinetics of γ‐cyclodextrin nanoparticle suspension eye drops in tear fluid (2014) (35)
- Development of a cyclodextrin-based aqueous cyclosporin A eye drop formulations. (2015) (35)
- γ-Cyclodextrin hydrogels and semi-interpenetrating networks for sustained delivery of dexamethasone (2010) (35)
- Self-assembled cyclodextrin nanoparticles and drug delivery (2014) (34)
- Improved delivery through biological membranes VIII: Design, synthesis, and in vivo testing of true prodrugs of aspirin. (1981) (33)
- Sulfobutylether-β-cyclodextrin/chitosan nano- and microparticles and their physicochemical characteristics. (2014) (33)
- Cyclodextrin solubilization of ETH-615, a zwitterionic drug. (1998) (32)
- Influence of cyclodextrins on the stability of the peptide salmon calcitonin in aqueous solution. (1999) (31)
- Improved acitretin delivery through hairless mouse skin by cyclodextrin complexation (1995) (31)
- Dexamethasone delivery to posterior segment of the eye (2007) (30)
- Physicochemical properties of water and its effect on drug delivery. A commentary. (2008) (30)
- Cyclodextrin–Amphiphilic Copolymer Supramolecular Assemblies for the Ocular Delivery of Natamycin (2019) (30)
- The effects of cyclodextrins on topical delivery of hydrocortisone: the aqueous diffusion layer (2003) (29)
- Effect of γ-cyclodextrin on solubilization and complexation of irbesartan: influence of pH and excipients. (2014) (29)
- Cyclodextrin–poloxamer aggregates as nanocarriers in eye drop formulations: dexamethasone and amphotericin B (2016) (28)
- Effect of cod-liver oil extract on the buccal permeation of ergotamine tartrate. (1998) (27)
- Parenteral Delivery of HPβCD: Effects on Drug-HSA Binding (2010) (27)
- Effects of cogrinding with β-cyclodextrin on the solid state fentanyl. (2010) (27)
- Self-assembly of cyclodextrins: formation of cyclodextrin polymer based nanoparticles (2012) (27)
- Cyclodextrins in Eye Drop Formulations (2002) (26)
- Effects of various cyclodextrins on the stability of freeze-dried lactate dehydrogenase. (2007) (26)
- Development of eye drops containing antihypertensive drugs: formulation of aqueous irbesartan/γCD eye drops (2015) (26)
- Drug Targeting to the Hair Follicles: A Cyclodextrin-Based Drug Delivery (2009) (26)
- gammaCD/HPgammaCD: synergistic solubilization. (2008) (26)
- Formulations and toxicologic in vivo studies of aqueous cyclosporin A eye drops with cyclodextrin nanoparticles. (2017) (26)
- Microspheres and Nanotechnology for Drug Delivery. (2016) (25)
- Solubilization and Stabilization of a Benzylpenicillin Chemical Delivery System by 2-Hydroxypropyl-β-cyclodextrin (1991) (25)
- γ-Cyclodextrin nanoparticle eye drops with dorzolamide: effect on intraocular pressure in man. (2014) (25)
- Effect of choline esters and oleic acid on the penetration of acyclovir, estradiol, hydrocortisone, nitroglycerin, retinoic acid and trifluorothymidine across hairless mouse skin in vitro. (1989) (25)
- Preparation, Characterization, and Anesthetic Properties of 2-Hydroxypropyl-β-cyclodextrin Complexes of Pregnanolone and Pregnenolone in Rat and Mouse (1995) (24)
- The self-assemble of natural cyclodextrins in aqueous solutions: Application of miniature permeation studies for critical aggregation concentration (cac) determinations. (2016) (24)
- Enalaprilat and enalapril maleate eyedrops lower intraocular pressure in rabbits (2009) (24)
- A New Approach for Quantitative Determination of γ-Cyclodextrin in Aqueous Solutions: Application in Aggregate Determinations and Solubility in Hydrocortisone/γ-Cyclodextrin Inclusion Complex. (2015) (23)
- Topically Effective Acetazolamide Eye-drop Solution in Man (1996) (23)
- Cyclodextrin-based telmisartan ophthalmic suspension: Formulation development for water-insoluble drugs. (2016) (23)
- Fatty acids from marine lipids: Biological activity, formulation and stability (2016) (22)
- The effect of cyclodextrins on the solubility and stability of medroxyprogesterone acetate and megestrol acetate in aqueous solution (1993) (22)
- Effects of 2-hydroxypropyl-beta-cyclodextrin on the aqueous solubility of drugs and transdermal delivery of 17 beta-estradiol. (1989) (22)
- Cyclodextrins as co-enhancers in dermal and transdermal drug delivery. (1998) (22)
- Fatty acids from cod-liver oil as skin penetration enhancers. (1995) (22)
- Dextran-based cyclodextrin polymers: their solubilizing effect and self-association. (2013) (21)
- Examination of 19F-NMR as a Tool for Investigation of Drug-Cyclodextrin Complexes (2003) (21)
- Soluble 1:1 complexes and insoluble 3:2 complexes - Understanding the phase-solubility diagram of hydrocortisone and γ-cyclodextrin. (2017) (21)
- In Vitro and Ex Vivo Evaluation of Nepafenac-Based Cyclodextrin Microparticles for Treatment of Eye Inflammation (2020) (21)
- Design and in vivo testing of 17β-estradiol-HPβCD sublingual tablets (1996) (20)
- Mucoadhesive Sustained Drug Delivery System Based on Cationic Polymer and Anionic Cyclodextrin/Triclosan Complex (2002) (20)
- Formulation and clinical evaluation of a hydrocortisone solution for the treatment of oral disease (1996) (20)
- Essential Pharmacokinetics: A Primer for Pharmaceutical Scientists (2015) (20)
- The effect of parenterally administered cyclodextrins on the pharmacokinetics of coadministered drugs. (2012) (20)
- Effect of oleic acid on diffusion of drugs through hairless mouse skin. (1989) (20)
- Improved delivery through biological membranes IX: Kinetics and mechanism of hydrolysis of methylsulfinymethyl 2-acetoxybenzoate and related aspirin prodrugs. (1981) (19)
- Cyclodextrin solubilization of celecoxib: solid and solution state characterization (2018) (19)
- Nepafenac-Loaded Cyclodextrin/Polymer Nanoaggregates: A New Approach to Eye Drop Formulation (2019) (18)
- Methazolamide 1% in cyclodextrin solution lowers IOP in human ocular hypertension. (2000) (18)
- Cyclodextrins in skin delivery (2000) (17)
- Drug loading in cyclodextrin polymers: dexamethasone model drug (2011) (17)
- Development of celecoxib eye drop solution and microsuspension: A comparative investigation of binary and ternary cyclodextrin complexes. (2019) (17)
- Self-Assembly of α-Cyclodextrin and β-Cyclodextrin: Identification and Development of Analytical Techniques. (2018) (16)
- Degradation of lomustine (CCNU) in aqueous solutions (1990) (16)
- Aqueous solubility and true solutions. (2010) (16)
- 2-Hydroxypropyl-β-Cyclodextrin Aggregates: Identification and Development of Analytical Techniques (2018) (16)
- Aqueous eye drops containing drug/cyclodextrin nanoparticles deliver therapeutic drug concentrations to both anterior and posterior segment. (2021) (15)
- The influence of cyclodextrins on the stability of cephalotin and aztreonam in aqueous solutions (1994) (15)
- Complexation—Use of Cyclodextrins to Improve Pharmaceutical Properties of Intramuscular Formulations (1999) (15)
- Aqueous solubility of kinase inhibitors: I the effect of hydrophilic polymers on their γ-cyclodextrin solubilization (2020) (15)
- Preparation and physical evaluation of microcapsules of hydrophilic drug-cyclodextrin complexes. (1992) (15)
- Drug Solubilization and Stabilization by Cyclodextrin Drug Carriers (2013) (15)
- Fish skin as a model membrane: structure and characteristics (2009) (14)
- Topical Drug Delivery to the Posterior Segment of the Eye: Thermodynamic Considerations. (2021) (14)
- Inclusion complexes of p-hydroxybenzoic acid esters and γ-cyclodextrin (2018) (13)
- Cationic quaternized aminocalix[4]arenes: cytotoxicity, haemolytic and antibacterial activities. (2013) (13)
- Cyclodextrin-accelerated degradation of β-lactam antibiotics in aqueous solutions (1991) (13)
- The Effects of Cyclodextrins on Hydrocortisone Permeability Through Semi-Permeable Membranes (2002) (13)
- The Use of Solubilizing Excipients and Approaches to GenerateToxicology Vehicles for Contemporary Drug Pipelines (2007) (13)
- Novel excipients – Regulatory challenges and perspectives – The EU insight (2018) (13)
- Cycloserine fatty acid derivatives as prodrugs: synthesis, degradation and in vitro skin permeability. (2002) (12)
- The Effect of Vehicle Additives on the Transdermal Delivery of Nitroglycerin (1987) (12)
- Formulation development and upscaling of lipid nanocapsules as a drug delivery system for a novel cyclic GMP analogue intended for retinal drug delivery. (2021) (12)
- Fatty Acid Extract From Cod‐liver Oil: Activity Against Herpes Simplex Virus and Enhancement of Transdermal Delivery of Acyclovir In‐vitro (1998) (12)
- For the special IJP issue "poorly soluble drugs". (2013) (12)
- Fish Skin as a Model Membrane to Study Transmembrane Drug Delivery with Cyclodextrins (2002) (12)
- Cyclodextrin‐Based Hydrogels (2011) (12)
- Cyclodextrin-based formulation of carbonic anhydrase inhibitors for ocular delivery - A review. (2021) (12)
- Evaluation of γ-cyclodextrin effect on permeation of lipophilic drugs: application of cellophane/fused octanol membrane (2017) (12)
- Stability characterization, kinetics and mechanism of tacrolimus degradation in cyclodextrin solutions. (2020) (12)
- Dorzolamide cyclodextrin nanoparticle suspension eye drops and Trusopt in rabbit. (2014) (12)
- Hydrolysis kinetics and QSAR investigation of soft antimicrobial agents (2005) (12)
- Pharmacokinetics and -dynamics of intramuscular and intranasal naloxone: an explorative study in healthy volunteers (2018) (12)
- Soft Drugs Based on Hydrocortisone: The Inactive Metabolite Approach and Its Application to Steroidal Antiinflammatory Agents (1999) (12)
- Topical Formulation Comprising Fatty Acid Extract from Cod Liver Oil: Development, Evaluation and Stability Studies (2016) (12)
- Formulation of Drug-Cyclodextrin Complexes (2015) (12)
- Formulation development for a zidovudine chemical delivery system 2. Towards oral and non-parenteral dosage forms (1995) (11)
- Soft Drugs VI. The Application of the Inactive Metabolite Approach for Design of Soft β-Blockers1?2 (1984) (11)
- Antifungal drug solubilizing activity and self-aggregation ability of cationic aminocalix[4]arene in comparison to SBEβCD: effect of addition of water-soluble polymer (2014) (11)
- Interaction of Native Cyclodextrins and Their Hydroxypropylated Derivatives with Carbamazepine in Aqueous Solution. Evaluation of Inclusion Complexes and Aggregates Formation (2019) (11)
- Angiotensin Receptor Blockers in cyclodextrin nanoparticle eye drops: Ocular pharmacokinetics and pharmacologic effect on intraocular pressure (2020) (11)
- Estramustine: hydrolysis, solubilization, and stabilization in aqueous solutions (1992) (11)
- Crystal Structure of Fentanyl Base (2009) (10)
- Unsaturated glycerol monoethers as novel skin penetration enhancers. (1997) (10)
- Cyclodextrins and the liquid-liquid phase distribution of progesterone, estrone and prednicarbate (2007) (10)
- Formulation development for a zidovudine chemical delivery system 1. Parenteral dosage forms (1995) (10)
- Clinical Trial: Marine Lipid Suppositories as Laxatives (2012) (10)
- Formation and stability assessment of self-assembled nanoparticles from large Mw chitosan and sulfobutylether-β-cyclodextrin (2015) (10)
- Topical drug delivery to the posterior segment of the eye: The effect of benzalkonium chloride on topical dexamethasone penetration into the eye in vivo (2018) (10)
- Cyclodextrins as Skin Penetration Enhancers (1996) (10)
- Interaction of native cyclodextrins and their hydroxypropylated derivatives with parabens in aqueous solutions. Part 1: evaluation of inclusion complexes (2019) (10)
- Self-assembled γ-cyclodextrin as nanocarriers for enhanced ocular drug bioavailability. (2022) (10)
- Self-assembly of cyclodextrin complexes: detection, obstacles and benefits. (2020) (10)
- Microcapsules Containing Water-Soluble Cyclodextrin Inclusion Complexes of Water-Insoluble Drugs (1993) (9)
- Interaction of fentanyl with various cyclodextrins in aqueous solutions (2016) (9)
- Improved Delivery Through Biological Membranes. XLV. Synthesis, Physical-Chemical Evaluation, and Brain Uptake Studies of 2-Chloroethyl Nitrosourea Delivery Systems (1992) (9)
- Applications of chemically-modified cyclodextrins: use of hydroxypropyl-β-cyclodextrin as an enabling excipient for brain targeting, redox-based derivatives of estradiol A review of preclinical and clinical findings (2004) (9)
- Age-related ocular conditions: Current treatments and role of cyclodextrin-based nanotherapies. (2021) (9)
- Effect of the cod-liver oil extract on the buccal permeation of ionized and nonionized forms of ergotamine using the keratinized epithelial-free membrane of hamster cheek pouch mucosa (1998) (9)
- Triclosan-loaded with high encapsulation efficiency into PLA nanoparticles coated with β-cyclodextrin polymer (2013) (9)
- Topical acetazolamide in 2-hydroxypropyl-beta-cyclodextrin eye drops lowers intraocular pressure in humans (1994) (8)
- Antifungal Activity of Econazole Nitrate/Cyclodextrin Complex: Effect of pH and Formation of Complex Aggregates. (2019) (8)
- Stabilizing effect of tris(hydroxymethyl)aminomethane on N-nitrosoureas in aqueous solutions. (1992) (8)
- Aqueous solubility of kinase inhibitors: II the effect of hexadimethrine bromide on the dovitinib/γ-cyclodextrin complexation (2020) (8)
- Cyclodextrin solubilization of water-insoluble drugs : calcipotriol and EB-1089 (1997) (8)
- The pharmacokinetics and transdermal delivery of loteprednol etabonate and related soft steroids (1994) (8)
- Effect of cyclodextrins on the degradation rate of benzylpenicillin. (2016) (7)
- Characterization and Evaluation of Ternary Complexes of Ascorbic Acid with γ-Cyclodextrin and Poly(vinyl Alcohol) (2020) (7)
- Topical drug delivery to the retina: obstacles and routes to success (2021) (7)
- Cyclodextrin‐Enhanced Drug Delivery through Mucous Membranes (2011) (7)
- Marine lipids for prodrugs, soft compounds and other pharmaceutical applications. (2000) (7)
- Solubilization and in vitro permeation of dovitinib/cyclodextrin complexes and their aggregates (2020) (7)
- Diacyl glyceryl ester prodrugs for slow release in the skin: synthesis and in vitro degradation and absorption studies for naproxen derivatives. (1999) (7)
- Physicochemical Properties and Pharmacokinetics (2015) (7)
- Drug Pharmacokinetics After Alternative Routes of Administration (2015) (6)
- Sublingual delivery of 17beta-estradiol from cyclodextrin containing tablets. (2003) (6)
- Self-assembled cyclodextrin-based nanoparticles for meropenem stabilization (2018) (6)
- Bio-Distribution and Pharmacokinetics of Topically Administered γ-Cyclodextrin Based Eye Drops in Rabbits (2021) (6)
- Development of octanol membranes for drug screening (2007) (6)
- Comparative study on inclusion complexation of acetylsalicylic acid, cholecalciferol and melphalan with β- and γ-cyclodextrin and some of their derivatives (1990) (6)
- Crystallographic and theoretical studies of an inclusion complex of β-cyclodextrin with fentanyl. (2017) (6)
- Can postoperative dexamethasone nanoparticle eye drops replace mitomycin C in trabeculectomy? (2020) (6)
- Cytotoxicity of β-Cyclodextrins in Retinal Explants for Intravitreal Drug Formulations (2021) (6)
- Topical Dexamethasone gamma-Cyclodextrin Nanoparticle Eye Drops increase Visual Acuity and decrease Macular Thickness in Diabetic Macular Edema (2015) (6)
- Preparation, characterization, and anesthetic properties of 2-hydroxypropyl-beta-cyclodextrin complexes of pregnanolone and pregnenolone in rat and mouse. (1995) (6)
- Fish skin as a model membrane: structure and characteristics. (2009) (6)
- Sustained drug delivery system based on a cationic polymer and an anionic drug/cyclodextrin complex. (2001) (6)
- Effect of porcine pancreatic α-amylase on dexamethasone release from aqueous solution containing natural γ-cyclodextrin. (2020) (5)
- Degradation of tauromustine (TCNU) in aqueous solutions. (1992) (5)
- Novel CD-Based Drug Delivery System (1996) (5)
- Stabilization and solubilization of difluprednate in aqueous cyclodextrin solution and its characterization for ophthalmic delivery (2022) (5)
- Evaluation of sugammadex self-association. (2011) (5)
- Disruption of α- and γ-cyclodextrin aggregates promoted by chaotropic agent (urea) (2018) (5)
- Novel Chemical Approaches for Sustained Drug Delivery (1987) (5)
- Stability of Peptides and Proteins (2014) (5)
- Synthesis of Cyclic Glycerol Ether Cyclodextrin Derivatives and Investigation of their Binding Properties with Drugs (1999) (5)
- Enhanced Complexation Efficacy of Cyclodextrins (1999) (5)
- Structural Characterization Study of a Lipid Nanocapsule Formulation Intended for Drug Delivery Applications Using Small-Angle Scattering Techniques (2022) (4)
- Free fatty acid suppositories are as effective as docusate sodium and sorbitol enemas in treating constipation in children (2016) (4)
- Stabilization of aspartame by cyclodextrins (1991) (4)
- Ocular powder: dry topical formulations of timolol are well tolerated in rabbits. (2006) (4)
- How Do Cyclodextrins Enhance Drug Permeability through Biological Membranes (1999) (4)
- The effect of 2-hydroxypropyl-β-cyclodextrin on the simultaneous dissolution and degradation of chlorambucil (1990) (4)
- Trifluorothymidine: potential non-invasive diagnosis of herpes simplex infection using 19F nuclear magnetic resonance in a murine hepatitis model☆☆☆ (1987) (4)
- Cyclodextrins and drug membrane permeation: Thermodynamic considerations. (2022) (4)
- Novel central nervous system targeted semisynthetic penicillins. (1990) (4)
- CD/HP CD: Synergistic solubilization (4)
- Poorly soluble drugs. (2020) (4)
- Design and Pharmaceutical Applications of Prodrugs (2010) (4)
- Development of Fenofibrate/Randomly Methylated β-Cyclodextrin-Loaded Eudragit® RL 100 Nanoparticles for Ocular Delivery (2022) (4)
- Physicochemical characterization and stability of microbeads containing cod-liver oil encircled with natural cyclodextrins (2014) (4)
- Clinical trial: free fatty acid suppositories compared with enema as bowel preparation for flexible sigmoidoscopy (2014) (4)
- Basic Concepts of Pharmacokinetics (2015) (3)
- Marine lipids as building blocks for soft quaternary ammonium compounds and their antibacterial activity. (2004) (3)
- Surface activity and self-aggregation ability of three cationic quaternized aminocalix[4]arenes (2014) (3)
- Interaction of native CDs and their hydroxypropyl derivatives with parabens in aqueous solutions. Part 2: evaluation of paraben/cyclodextrin complex aggregation (2019) (3)
- Lipophilic metronidazole derivatives and their absorption through hairless mouse skin. (2000) (3)
- Cyclodextrin complexes of a globular protein and a lipophilic oligopeptide: the effect of structure and physicochemical properties. (2017) (3)
- 1,4-Benzodiazepines: Chemical stability and cyclodextrin solubilization (2021) (3)
- Aqueous solubility of kinase inhibitors: III the effect of acidic counter ion on the dovitinib/γ-cyclodextrin complexation (2020) (3)
- Design and in vivo testing of 17 beta-estradiol-HP beta CD sublingual tablets. (1996) (3)
- Effect of cyclodextrins on the degradation of cortisone acetate, œstradiol benzoate and prednicarbate in aqueous solution (1994) (3)
- Diffusion in the Vitreous Cavity Is Related to the Viscosity of the Medium According to the Stokes Einstein Equation (2007) (3)
- Drug-cyclodextrin-polymer ternary complexes (1996) (3)
- Physicochemical and Stability Evaluation of Topical Niosomal Encapsulating Fosinopril/γ-Cyclodextrin Complex for Ocular Delivery (2022) (3)
- Complexation Properties of ß-Cyclodextrin Sulfobutylether Sodium Salt (1999) (3)
- Solubilization of -cyclodextrin (1996) (3)
- Solubilization of β-Cyclodextrin (1996) (3)
- Effect of β- and γ-cyclodextrins and their methylated derivatives on the degradation rate of benzylpenicillin (2018) (2)
- Solubility and stability of cediranib maleate (2021) (2)
- The effect of ionization on partition coefficients and topical delivery. (1985) (2)
- Evaluation of Degradation Studies Performed in Aqueous Cyclodextrin Solutions (1999) (2)
- Kinetics of dexamethasone cyclodextrin nanoparticle suspension eye drops in tear fluid (2013) (2)
- Synthesis and evaluation of novel lidocaine sulfur analogs (1984) (2)
- Solution Enhancement of Drug Substances using Soluble Amylose (2011) (2)
- Effect of salt formation on γ-cyclodextrin solubilization of irbesartan and candesartan and the chemical stability of their ternary complexes (2021) (2)
- Solubility and permeability of steroids in water in the presence of potassium halides. (2010) (2)
- Principles of Drug Degradation (2014) (2)
- Dermal Delivery of ETH-615, a Zwitterionic Drug (2000) (2)
- Integration of cyclodextrins and associated toxicities: A roadmap for high quality biomedical applications. (2022) (2)
- The stability of aspartame in aqueous solutions (1992) (2)
- Su1100 Marine Lipid Suppositories for Constipation in Children (2013) (2)
- PHARMACEUTICAL TECHNOLOGY Effects of Cogrinding with b-Cyclodextrin on the Solid State Fentanyl (2010) (2)
- Water Soluble Complexes of a Brain-Targeted Drug Delivery System (1988) (2)
- Drug—Cyclodextrin Complexation in the Presence of Water-Soluble Polymers: Enhanced Solubility and Percutaneous Transport (1999) (1)
- Pharmacy in Iceland (1994) (1)
- Chapter 7 – Stability Testing (2014) (1)
- Effect of Soluplus® on γ-cyclodextrin solubilization of irbesartan and candesartan and their nanoaggregates formation (2021) (1)
- Complexation of Drug Compounds with Ionic and Non-Ionic Cyclodextrins. (1996) (1)
- CHAPTER 13 – Microspheres and nanotechnology for drug delivery (2010) (1)
- Effect of various marine lipids on transdermal drug delivery--in vitro evaluation. (1997) (1)
- A Current Overview of Cyclodextrin-Based Nanocarriers for Enhanced Antifungal Delivery (2022) (1)
- Drug Degradation in Semisolid Dosage Forms (2014) (1)
- Chapter 7 – Practice Problems (2015) (1)
- Chapter 3 – Degradation Pathways (2014) (1)
- Aqueous Prostaglandin Eye Drop Formulations (2022) (1)
- Topical noninvasive retinal drug delivery of a tyrosine kinase inhibitor: 3% cediranib maleate cyclodextrin nanoparticle eye drops in the rabbit eye (2022) (1)
- Angiotensin converting enzyme inhibitors/cyclodextrin inclusion complexes: solution and solid-state characterizations and their thermal stability (2022) (1)
- Role of Topical versus Systemic Absorption in Delivery of Dexamethasone to the Anterior and Posterior Segments of the Rabbit Eye (2006) (1)
- Editorial: in memoriam Dr. Marcus Brewster. (2014) (1)
- Preformulation studies of dovitinib free base: Solubility, Lipophilicity and Stability. (2022) (0)
- Pharmacokinetics and -dynamics of intramuscular and intranasal naloxone: an explorative study in healthy volunteers (2018) (0)
- Transdermal administration system. (1986) (0)
- Pharmacologic Response and Drug Dosage Adjustments (2015) (0)
- Angiotensin II receptor blockers in nanoparticle eye drops lower IOP in rabbits (2019) (0)
- Preface: First European cyclodextrin conference (2011) (0)
- Dorzolamide Cyclodextrin Nanoparticle Eye Drops Lower Intraocular Pressure Over 24 Hours (2012) (0)
- ChemInform Abstract: Cycloserine Fatty Acid Derivatives (VI) as Prodrugs: Synthesis, Degradation and in vitro Skin Permeability. (2010) (0)
- Effects of polymers on cyclodextrin complexation and drug bioavailability (1996) (0)
- Topical dexamethasone delivery to the retina: An aqueous cyclodextrin-based microsuspension (2023) (0)
- Topical delivery of acetazolamide for psoriasis. (1993) (0)
- Nanoparticles for drug delivery (2012) (0)
- Characterization of cyclodextrin polymers: stability, drug loading and release. (2009) (0)
- Aqueous Cyclosporin A Eye Drop Formulations with Cyclodextrin Nanoparticles (2017) (0)
- Synthesis of Cyclodextrin Glycerol Ethers and Investigation of their Binding Properties (1999) (0)
- A 11 Patent Number : 45 Date of Patent : 5 , 324 , 718 Jun . 28 , 1994 (2017) (0)
- Chapter 8 – Problems (2014) (0)
- The effect of phosphine oxides on transdermal delivery. (1990) (0)
- Dexamethasone nanoparticle eye drops to replace Mitomycin C as postoperative treatment following trabeculectomy (2017) (0)
- Influence of Cyclodextrins on the Chemical Stability of Salmon Calcitonin in Aqueous Solution (1999) (0)
- Drug Degradation in Solid State (2014) (0)
- Nanotechnology cyclodextrin for administration ophthalmic drug (2006) (0)
- Diffusion of Oxygen is Slower in Vitreous Gel Than in Saline in Agreement With the Stokes Einstein Equation (2009) (0)
- United States Patent ( 10 ) Patent No . : US 7 , 678 , 776 B 2 (2017) (0)
- The Effect of Food and Excipients on Drug Pharmacokinetics (2015) (0)
- Voriconazole Eye Drops: Enhanced Solubility and Stability through Ternary Voriconazole/Sulfobutyl Ether β-Cyclodextrin/Polyvinyl Alcohol Complexes (2023) (0)
- Anomalous Properties of Cyclodextrins and Their Complexes in Aqueous Solutions (2023) (0)
- Ocular Powder: Irritation Studies of Dry Formulations of Topical Timolol (2005) (0)
- Investigation of soft long chain quaternary ammonium compounds as co-factors to enhance in vitro gene delivery. (2006) (0)
- 2-Hydroxypropyl-ß-Cyclodextrin in Eye Drops. Evaluation of Artificial Tear-Drops In Human Patients (1996) (0)
- Topical treatment of diabetic macular edema using dexamethasone ophthalmic suspension: A randomized, double‐masked, vehicle‐controlled study (2022) (0)
- Aggregate Determination by Permeation Technique. (2021) (0)
- Effect of 2-Hydroxypropyl-β-Cyclodextrin Complexes of the Neurosteroids, Alfaxalone, Pregnanolone and Pregnenolone, on Various Convulsant Stimuli in the Mouse (1996) (0)
- Self-Assembled Dorzolamide/-Cyclodextrin Microparticle Eye Drops (2011) (0)
- CYCLODEXTRINS AS SKIN PENETRATION ENHANCERS Effects of polymers on cyclodextrin complexation and transdermal drug delivery (1996) (0)
- Editorial Special edition of International Journal of Pharmaceutics in honor of Professor Dominique Duchêne. (2017) (0)
- A Tribute to Dr. Marcus E. Brewster: October 14, 1957-September 15, 2014. (2016) (0)
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What Schools Are Affiliated With Thorsteinn Loftsson?
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