Tim Sparwasser
Researcher
Tim Sparwasser's AcademicInfluence.com Rankings

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Computer Science
Tim Sparwasser's Degrees
- PhD Computer Science University of California, Berkeley
- Masters Computer Science Stanford University
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Why Is Tim Sparwasser Influential?
(Suggest an Edit or Addition)According to Wikipedia, Tim Dominik Sparwasser is a German physician, microbiologist and infection immunologist. In 2018, he became director of the Institute for Medical Microbiology and Hygiene in Mainz. Education and career Sparwasser studied human medicine at the Johannes Gutenberg-University Mainz and at the Ludwig-Maximilians-University Munich as a scholarship holder of the Studienstiftung des Deutschen Volkes; he received his doctor of medicine in 1996. He continued his research first at the Institute for Medical Microbiology, Immunology and Hygiene at the Technical University Munich and afterwards at the Skirball Institute in New York as a Howard Hughes Medical Institute Postdoctoral Fellow .
Tim Sparwasser's Published Works
Published Works
- In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens. (2002) (1881)
- Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease (2007) (946)
- Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells (1998) (899)
- Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity (2006) (808)
- Intestinal tolerance requires gut homing and expansion of FoxP3+ regulatory T cells in the lamina propria. (2011) (772)
- CpG‐DNA‐specific activation of antigen‐presenting cells requires stress kinase activity and is preceded by non‐specific endocytosis and endosomal maturation (1998) (745)
- De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells (2014) (617)
- T cell receptor stimulation-induced epigenetic changes and Foxp3 expression are independent and complementary events required for Treg cell development. (2012) (612)
- Bacterial DNA causes septic shock (1997) (448)
- Macrophages sense pathogens via DNA motifs: induction of tumor necrosis factor‐α‐mediated shock (1997) (403)
- CD73-deficient mice have increased antitumor immunity and are resistant to experimental metastasis. (2011) (344)
- Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis. (2013) (315)
- IL-7 Engages Multiple Mechanisms to Overcome Chronic Viral Infection and Limit Organ Pathology (2011) (313)
- Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature. (2013) (292)
- DC activated via dectin-1 convert Treg into IL-17 producers (2008) (292)
- Fatty acid metabolism in the regulation of T cell function. (2015) (290)
- Metabolic pathways in T cell activation and lineage differentiation. (2016) (289)
- A Weaning Reaction to Microbiota Is Required for Resistance to Immunopathologies in the Adult. (2019) (288)
- Foxp3+ T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation (2015) (283)
- Immunostimulatory DNA: Sequence‐dependent production of potentially harmful or useful cytokines (1997) (274)
- Selective depletion of Foxp3+ regulatory T cells improves effective therapeutic vaccination against established melanoma. (2010) (257)
- Tolerance rather than immunity protects from Helicobacter pylori-induced gastric preneoplasia. (2011) (253)
- PD-L1hi B cells are critical regulators of humoral immunity (2015) (238)
- Immunostimulatory CpG-oligonucleotides cause proliferation, cytokine production, and an immunogenic phenotype in chronic lymphocytic leukemia B cells. (2000) (237)
- Etomoxir Actions on Regulatory and Memory T Cells Are Independent of Cpt1a-Mediated Fatty Acid Oxidation. (2018) (221)
- Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies (2009) (221)
- Neuropilin 1 deficiency on CD4+Foxp3+ regulatory T cells impairs mouse melanoma growth (2012) (212)
- Maturation of Lymph Node Fibroblastic Reticular Cells from Myofibroblastic Precursors Is Critical for Antiviral Immunity (2013) (211)
- Interleukin 9 fate reporter reveals induction of innate IL-9 response in lung inflammation (2011) (210)
- Etomoxir Inhibits Macrophage Polarization by Disrupting CoA Homeostasis. (2018) (195)
- Regulatory T cells suppress muscle inflammation and injury in muscular dystrophy (2014) (193)
- Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation (2011) (191)
- Conditional regulatory T-cell depletion releases adaptive immunity preventing carcinogenesis and suppressing established tumor growth. (2010) (191)
- Bacterial CpG‐DNA activates dendritic cells in vivo: T helper cell‐independent cytotoxic T cell responses to soluble proteins (2000) (188)
- CD4+ T Cell Tolerance to Tissue-Restricted Self Antigens Is Mediated by Antigen-Specific Regulatory T Cells Rather Than Deletion. (2015) (184)
- Foxp3+ T cells induce perforin-dependent dendritic cell death in tumor-draining lymph nodes. (2010) (182)
- Cutting Edge: Depletion of Foxp3+ Cells Leads to Induction of Autoimmunity by Specific Ablation of Regulatory T Cells in Genetically Targeted Mice1 (2009) (181)
- Gut-tropic T cells that express integrin α4β7 and CCR9 are required for induction of oral immune tolerance in mice. (2011) (178)
- CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis (2011) (175)
- Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2–P2X7 pathway (2010) (168)
- Schistosomes Induce Regulatory Features in Human and Mouse CD1dhi B Cells: Inhibition of Allergic Inflammation by IL-10 and Regulatory T Cells (2012) (162)
- Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection (2012) (159)
- Immunostimulatory CpG-oligodeoxynucleotides cause extramedullary murine hemopoiesis. (1999) (157)
- In vivo depletion of FoxP3+ Tregs using the DEREG mouse model. (2011) (156)
- Langerhans cells protect from allergic contact dermatitis in mice by tolerizing CD8(+) T cells and activating Foxp3(+) regulatory T cells. (2012) (154)
- CpG-DNA-Mediated Transient Lymphadenopathy Is Associated with a State of Th1 Predisposition to Antigen-Driven Responses1 (2000) (152)
- Macrophages sense pathogens via DNA motifs: induction of tumor necrosis factor-alpha-mediated shock. (1997) (152)
- The regulatory T-cell response during acute retroviral infection is locally defined and controls the magnitude and duration of the virus-specific cytotoxic T-cell response. (2009) (142)
- The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma (2010) (141)
- Regulatory T Cells Increase the Avidity of Primary CD8+ T Cell Responses and Promote Memory (2012) (136)
- Selective and efficient generation of functional Batf3-dependent CD103+ dendritic cells from mouse bone marrow. (2014) (134)
- The Bcl10–Malt1 complex segregates FcɛRI-mediated nuclear factor κB activation and cytokine production from mast cell degranulation (2006) (125)
- Identification and expansion of highly suppressive CD8(+)FoxP3(+) regulatory T cells after experimental allogeneic bone marrow transplantation. (2012) (117)
- Regulatory T cells in the bone marrow microenvironment in patients with prostate cancer (2012) (116)
- Foxp3+ regulatory T cells protect the liver from immune damage and compromise virus control during acute experimental hepatitis B virus infection in mice (2012) (114)
- Targeting DC-SIGN via its neck region leads to prolonged antigen residence in early endosomes, delayed lysosomal degradation, and cross-presentation. (2011) (114)
- Targeting glycan modified OVA to murine DC-SIGN transgenic dendritic cells enhances MHC class I and II presentation. (2009) (113)
- Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma (2016) (111)
- CD4+ Natural Regulatory T Cells Prevent Experimental Cerebral Malaria via CTLA-4 When Expanded In Vivo (2010) (110)
- Sialic acid-modified antigens impose tolerance via inhibition of T-cell proliferation and de novo induction of regulatory T cells (2016) (110)
- T helper type 1 memory cells disseminate postoperative ileus over the entire intestinal tract (2010) (108)
- Transient depletion of regulatory T cells in transgenic mice reactivates virus-specific CD8+ T cells and reduces chronic retroviral set points (2011) (105)
- Platelet-derived growth factor-producing CD4+ Foxp3+ regulatory T lymphocytes promote lung fibrosis. (2011) (97)
- FoxP3+ regulatory T cells essentially contribute to peripheral CD8+ T-cell tolerance induced by steady-state dendritic cells (2010) (91)
- Decreased Pathology and Prolonged Survival of Human DC-SIGN Transgenic Mice during Mycobacterial Infection1 (2008) (89)
- Establishment of nematode infection despite increased Th2 responses and immunopathology after selective depletion of Foxp3+ cells (2009) (88)
- CD8+Foxp3+ T cells share developmental and phenotypic features with classical CD4+Foxp3+ regulatory T cells but lack potent suppressive activity (2011) (88)
- Rapid In Vivo Conversion of Effector T Cells into Th2 Cells during Helminth Infection (2012) (88)
- Regulatory T cells control the Th1 immune response in murine crescentic glomerulonephritis (2011) (87)
- Strongyloides ratti Infection Induces Expansion of Foxp3+ Regulatory T Cells That Interfere with Immune Response and Parasite Clearance in BALB/c Mice (2011) (87)
- Transient ablation of regulatory T cells improves antitumor immunity in colitis-associated colon cancer. (2014) (85)
- A Major Role for Myeloid-Derived Suppressor Cells and a Minor Role for Regulatory T Cells in Immunosuppression during Staphylococcus aureus Infection (2015) (84)
- Tregs restrain dendritic cell autophagy to ameliorate autoimmunity (2017) (83)
- Alternating 2'-O-ribose methylation is a universal approach for generating non-stimulatory siRNA by acting as TLR7 antagonist. (2010) (82)
- Functional and Antigenic Characterization of Human, Rhesus Macaque, Pigtailed Macaque, and Murine DC-SIGN (2001) (82)
- Fatty acid metabolism in CD8+ T cell memory: Challenging current concepts (2018) (82)
- Toll-like receptor 9 contributes to recognition of Mycobacterium bovis Bacillus Calmette-Guérin by Flt3-ligand generated dendritic cells. (2006) (81)
- IκB(NS) protein mediates regulatory T cell development via induction of the Foxp3 transcription factor. (2012) (79)
- Regulatory T Cells Selectively Control CD8+ T Cell Effector Pool Size via IL-2 Restriction (2011) (79)
- General method for the modification of different BAC types and the rapid generation of BAC transgenic mice (2004) (78)
- IL-21 Restricts Virus-driven Treg Cell Expansion in Chronic LCMV Infection (2013) (77)
- Regulatory T Cells Suppress Antiviral Immune Responses and Increase Viral Loads during Acute Infection with a Lymphotropic Retrovirus (2009) (75)
- Nonfunctional Regulatory T Cells and Defective Control of Th2 Cytokine Production in Natural Scurfy Mutant Mice1 (2009) (73)
- Regulatory T cells control tolerogenic versus autoimmune response to sperm in vasectomy (2011) (72)
- α-MSH-stimulated tolerogenic dendritic cells induce functional regulatory T cells and ameliorate ongoing skin inflammation. (2012) (72)
- CD28 superagonist-mediated boost of regulatory T cells increases thrombo-inflammation and ischemic neurodegeneration during the acute phase of experimental stroke (2014) (69)
- C-X-C Motif Chemokine Receptor 4 Blockade Promotes Tissue Repair After Myocardial Infarction by Enhancing Regulatory T Cell Mobilization and Immune-Regulatory Function (2019) (68)
- The oral administration of bacterial extracts prevents asthma via the recruitment of regulatory T cells to the airways. (2011) (67)
- Highly self-reactive naive CD4 T cells are prone to differentiate into regulatory T cells (2013) (64)
- Regulatory T cells promote a protective Th17-associated immune response to intestinal bacterial infection with C. rodentium (2014) (62)
- Schistosoma mansoni-Mediated Suppression of Allergic Airway Inflammation Requires Patency and Foxp3+ Treg Cells (2013) (62)
- Regulating T cell differentiation through the polyamine spermidine. (2020) (62)
- In vivo reprogramming of UV radiation-induced regulatory T-cell migration to inhibit the elicitation of contact hypersensitivity. (2011) (61)
- CD103hi Treg cells constrain lung fibrosis induced by CD103lo tissue-resident pathogenic CD4 T cells (2019) (60)
- Immunostimulatory RNA Blocks Suppression by Regulatory T Cells (2009) (60)
- Regulatory T cells facilitate the nuclear accumulation of inducible cAMP early repressor (ICER) and suppress nuclear factor of activated T cell c1 (NFATc1) (2011) (60)
- Selective Treg reconstitution during lymphopenia normalizes DC costimulation and prevents graft-versus-host disease. (2015) (58)
- Efficient oral vaccination by bioengineering virus-like particles with protozoan surface proteins (2019) (57)
- On the Role of Regulatory T Cells during Viral-Induced Inflammatory Lesions (2012) (56)
- Immunometabolism and autoimmunity (2016) (56)
- Foxp3+ cells control Th2 responses in a murine model of atopic dermatitis. (2012) (55)
- Low-level regulatory T-cell activity is essential for functional type-2 effector immunity to expel gastrointestinal helminths (2015) (55)
- Selective depletion of Foxp3+ Treg during sensitization phase aggravates experimental allergic airway inflammation (2010) (54)
- Activation of dendritic cells via TLR7 reduces Foxp3 expression and suppressive function in induced Tregs (2011) (54)
- Foxp3-Mediated Suppression of CD95L Expression Confers Resistance to Activation-Induced Cell Death in Regulatory T Cells (2011) (54)
- Enzymatic Activity of HPGD in Treg Cells Suppresses Tconv Cells to Maintain Adipose Tissue Homeostasis and Prevent Metabolic Dysfunction. (2019) (54)
- Secretory phospholipase A2-IID is an effector molecule of CD4+CD25+ regulatory T cells (2009) (53)
- Infiltrating Foxp3+ Regulatory T Cells From Spontaneously Tolerant Kidney Allografts Demonstrate Donor‐Specific Tolerance (2013) (53)
- Active suppression of intestinal CD4+TCRαβ+ T-lymphocyte maturation during the postnatal period (2015) (52)
- Layers of dendritic cell-mediated T cell tolerance, their regulation and the prevention of autoimmunity (2012) (52)
- Strong Impact of CD4+Foxp3+ Regulatory T Cells and Limited Effect of T Cell-Derived IL-10 on Pathogen Clearance during Plasmodium yoelii Infection (2012) (52)
- Limited Role of CD4+Foxp3+ Regulatory T Cells in the Control of Experimental Cerebral Malaria1 (2009) (51)
- Foxp3+ Regulatory T Cells Play a Protective Role in Angiotensin II–Induced Aortic Aneurysm Formation in Mice (2015) (50)
- 1,25-dihydroxyvitamin D exerts similar immunosuppressive effects as UVR but is dispensable for local UVR-induced immunosuppression. (2012) (48)
- Tregs in infection and vaccinology: heroes or traitors? (2012) (47)
- Virus-induced tumor inflammation facilitates effective DC cancer immunotherapy in a Treg-dependent manner in mice. (2011) (46)
- Immunostimulatory Effects Triggered by Enterococcus faecalis CECT7121 Probiotic Strain Involve Activation of Dendritic Cells and Interferon-Gamma Production (2015) (46)
- Absence of Siglec-H in MCMV Infection Elevates Interferon Alpha Production but Does Not Enhance Viral Clearance (2013) (46)
- Foxp3+ Regulatory T Cells Delay Expulsion of Intestinal Nematodes by Suppression of IL-9-Driven Mast Cell Activation in BALB/c but Not in C57BL/6 Mice (2014) (44)
- CD4+FoxP3+ regulatory T cells suppress fatal T helper 2 cell immunity during pulmonary fungal infection (2014) (43)
- IL-33/ST2 pathway drives regulatory T cell dependent suppression of liver damage upon cytomegalovirus infection (2017) (43)
- Bacterial DNA as an evolutionary conserved ligand signalling danger of infection to immune cells (1998) (42)
- Regulatory T Cells Selectively Preserve Immune Privilege of Self-Antigens during Viral Central Nervous System Infection (2012) (42)
- Regulatory T cells and T‐cell‐derived IL‐10 interfere with effective anti‐cytomegalovirus immune response (2014) (41)
- Foxp3+ Regulatory T Cells Are Required for Recovery from Severe Sepsis (2013) (41)
- Disruption of de novo fatty acid synthesis via acetyl‐CoA carboxylase 1 inhibition prevents acute graft‐versus‐host disease (2016) (40)
- Contribution of regulatory T cells to alleviation of experimental allergic asthma after specific immunotherapy (2012) (39)
- Regulatory T Cells Suppress Inflammation and Blistering in Pemphigoid Diseases (2017) (38)
- BAC to immunology – bacterial artificial chromosome‐mediated transgenesis for targeting of immune cells (2007) (38)
- Melanocortin-1 receptor activation is neuroprotective in mouse models of neuroinflammatory disease (2016) (38)
- In vivo targeting of human DC‐SIGN drastically enhances CD8+ T‐cell‐mediated protective immunity (2013) (38)
- Thymus‐derived regulatory T cells restrain pro‐inflammatory Th1 responses by downregulating CD70 on dendritic cells (2015) (37)
- Few Foxp3+ regulatory T cells are sufficient to protect adult mice from lethal autoimmunity (2014) (36)
- Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis (2019) (36)
- The Immunotherapeutic Role of Regulatory T Cells in Leishmania (Viannia) panamensis Infection (2014) (36)
- Treg‐cell depletion promotes chemokine production and accumulation of CXCR3+ conventional T cells in intestinal tumors (2015) (36)
- A Novel Bacterial Artificial Chromosome-Transgenic Podoplanin–Cre Mouse Targets Lymphoid Organ Stromal Cells in vivo (2011) (36)
- Foxp3+ T cells inhibit antitumor immune memory modulated by mTOR inhibition. (2014) (35)
- Loss of the TGFβ-Activating Integrin αvβ8 on Dendritic Cells Protects Mice from Chronic Intestinal Parasitic Infection via Control of Type 2 Immunity (2013) (34)
- The Special Relationship in the Development and Function of T Helper 17 and Regulatory T Cells. (2015) (34)
- The temporal and spatial dynamics of Foxp3+ Treg cell-mediated suppression during contact hypersensitivity responses in a murine model. (2012) (34)
- Development of a unique epigenetic signature during in vivo Th17 differentiation (2015) (33)
- Long-term prevention of chronic allograft rejection by regulatory T-cell immunotherapy involves host Foxp3-expressing T cells. (2013) (32)
- Ligation of TLR7 on CD19+CD1dhi B cells suppresses allergic lung inflammation via regulatory T cells (2015) (32)
- Conventional Dendritic Cells Confer Protection against Mouse Cytomegalovirus Infection via TLR9 and MyD88 Signaling. (2016) (32)
- De Novo Fatty Acid Synthesis During Mycobacterial Infection Is a Prerequisite for the Function of Highly Proliferative T Cells, But Not for Dendritic Cells or Macrophages (2018) (30)
- Conventional Bone Marrow-Derived Dendritic Cells Contribute to Toll-Like Receptor-Independent Production of Alpha/Beta Interferon in Response to Inactivated Parapoxvirus Ovis (2009) (30)
- Multiple Layers of CD80/86-Dependent Costimulatory Activity Regulate Primary, Memory, and Secondary Lymphocytic Choriomeningitis Virus-Specific T Cell Immunity (2011) (30)
- Dendritic cell specific targeting of MyD88 signalling pathways in vivo (2015) (29)
- Rapid Rebound of the Treg Compartment in DEREG Mice Limits the Impact of Treg Depletion on Mycobacterial Burden, but Prevents Autoimmunity (2014) (29)
- Circumvention of regulatory CD4+ T cell activity during cross‐priming strongly enhances T cell‐mediated immunity (2008) (29)
- Foxp3+ Regulatory T Cells Control Persistence of Viral CNS Infection (2012) (29)
- Antigen targeting to dendritic cells combined with transient regulatory T cell inhibition results in long-term tumor regression (2014) (29)
- Advantages of Foxp3+ regulatory T cell depletion using DEREG mice (2014) (28)
- Inhibiting CXCR3-Dependent CD8+ T Cell Trafficking Enhances Tolerance Induction in a Mouse Model of Lung Rejection (2011) (28)
- A limited role for regulatory T cells in post-ischemic neovascularization (2012) (27)
- Dendritic cells coordinate innate immunity via MyD88 signaling to control Listeria monocytogenes infection. (2014) (26)
- Anti-CD4 treatment inhibits autoimmunity in scurfy mice through the attenuation of co-stimulatory signals. (2014) (26)
- Foxp3+ Regulatory T Cells in Mouse Models of Type 1 Diabetes (2013) (26)
- The Absence of HIF-1α Increases Susceptibility to Leishmania donovani Infection via Activation of BNIP3/mTOR/SREBP-1c Axis. (2020) (25)
- Notch and TLR signaling coordinate monocyte cell fate and inflammation (2020) (25)
- TGFβ-activation by dendritic cells drives Th17 induction and intestinal contractility and augments the expulsion of the parasite Trichinella spiralis in mice (2019) (24)
- MyD88 signaling in dendritic cells and the intestinal epithelium controls immunity against intestinal infection with C. rodentium (2017) (24)
- Antigen receptor-mediated depletion of FOXP3 in induced regulatory T-lymphocytes via PTPN2 and FOXO1 (2015) (24)
- Combination of nanoparticle-based therapeutic vaccination and transient ablation of regulatory T cells enhances anti-viral immunity during chronic retroviral infection (2016) (24)
- Lung epithelium and myeloid cells cooperate to clear acute pneumococcal infection (2015) (24)
- MyD88 signalling in myeloid cells is sufficient to prevent chronic mycobacterial infection (2014) (23)
- Cytokines, Antibodies, and Histopathological Profiles during Giardia Infection and Variant-Specific Surface Protein-Based Vaccination (2018) (23)
- Gene Trap Mice Reveal an Essential Function of Dual Specificity Phosphatase Dusp16/MKP-7 in Perinatal Survival and Regulation of Toll-like Receptor (TLR)-induced Cytokine Production* (2013) (23)
- Depletion of Regulatory T Cells Augments a Vaccine-Induced T Effector Cell Response against the Liver-Stage of Malaria but Fails to Increase Memory (2014) (22)
- Fluorochrome‐based definition of naturally occurring Foxp3+ regulatory T cells of intra‐ and extrathymic origin (2014) (22)
- Absence of Foxp3+ Regulatory T Cells during Allergen Provocation Does Not Exacerbate Murine Allergic Airway Inflammation (2012) (22)
- Microbe-associated immunomodulatory metabolites: Influence on T cell fate and function. (2015) (21)
- 1 I κ BNS protein mediates regulatory T cell development via induction of the Foxp 3 transcription factor (2013) (21)
- Regulatory CD4+Foxp3+ T Cells Control the Severity of Anaphylaxis (2013) (21)
- Tumor-specific CD4+ T cells develop cytotoxic activity and eliminate virus-induced tumor cells in the absence of regulatory T cells (2012) (21)
- Lack of Foxp3+ macrophages in both untreated and B16 melanoma-bearing mice. (2012) (20)
- The adjuvant effect of TLR agonists on CD4+ effector T cells is under the indirect control of regulatory T cells (2011) (19)
- De Novo–Induced Self-Antigen–Specific Foxp3+ Regulatory T Cells Impair the Accumulation of Inflammatory Dendritic Cells in Draining Lymph Nodes (2015) (19)
- CD4+ T-cell differentiation and function: Unifying glycolysis, fatty acid oxidation, polyamines NAD mitochondria. (2021) (18)
- FoxP3+ Regulatory T Cells Determine Disease Severity in Rodent Models of Inflammatory Neuropathies (2014) (18)
- Consequences of bacterial CpG DNA-driven activation of antigen-presenting cells. (2000) (15)
- Treg depletion attenuates the severity of skin disease from ganglionic spread after HSV-2 flank infection. (2013) (15)
- The human cytomegalovirus glycoprotein pUL11 acts via CD45 to induce T cell IL-10 secretion (2017) (15)
- Dendritic cells conditioned by activin A–induced regulatory T cells exhibit enhanced tolerogenic properties and protect against experimental asthma (2017) (14)
- Regulatory T cells control endothelial chemokine production and migration of T cells into intestinal tumors of APCmin/+ mice (2018) (14)
- Schistosome-induced pulmonary B cells inhibit allergic airway inflammation and display a reduced Th2-driving function. (2017) (14)
- Hematopoietic remodeling triggered by CpG DNA. (2000) (14)
- Targeting Mycobacterium tuberculosis Antigens to Dendritic Cells via the DC-Specific-ICAM3-Grabbing-Nonintegrin Receptor Induces Strong T-Helper 1 Immune Responses (2018) (13)
- Genetic variants harbored in the forkhead box protein 3 locus increase hay fever risk. (2010) (13)
- TLR4 abrogates the Th1 immune response through IRF1 and IFN-β to prevent immunopathology during L. infantum infection (2020) (13)
- Vagaries of Fluorochrome Reporter Gene Expression in Foxp3+ Regulatory T Cells (2012) (13)
- CD4 blockade directly inhibits mouse and human CD4(+) T cell functions independent of Foxp3(+) Tregs. (2013) (13)
- Targeting cellular fatty acid synthesis limits T helper and innate lymphoid cell function during intestinal inflammation and infection (2020) (13)
- A new RelB‐dependent CD117+CD172a+ murine DC subset preferentially induces Th2 differentiation and supports airway hyperresponses in vivo (2018) (12)
- Toll-like receptor-2 agonist-allergen coupling efficiently redirects Th2 cell responses and inhibits allergic airway eosinophilia. (2012) (12)
- Regulatory T Cells in an Endogenous Mouse Lymphoma Recognize Specific Antigen Peptides and Contribute to Immune Escape (2019) (12)
- The Transcription Factor MAZR/PATZ1 Regulates the Development of FOXP3+ Regulatory T Cells. (2019) (11)
- Metabolites: deciphering the molecular language between DCs and their environment (2017) (11)
- In vivo activation of Treg cells with a CD28 superagonist prevents and ameliorates chronic destructive arthritis in mice (2016) (11)
- Mouse Cytomegalovirus infection overrules T regulatory cell suppression on natural killer cells (2014) (11)
- Selective Expression of the MAPK Phosphatase Dusp9/MKP-4 in Mouse Plasmacytoid Dendritic Cells and Regulation of IFN-β Production (2015) (10)
- Optimal Isolation of Functional Foxp3+ Induced Regulatory T Cells Using DEREG Mice (2012) (10)
- Direct recognition of hepatocyte-expressed MHC class I alloantigens is required for tolerance induction. (2018) (10)
- Regulatory T Cells Limit Pneumococcus-Induced Exacerbation of Lung Fibrosis in Mice (2020) (10)
- Microenvironment and Immunology CD 73-Deficient Mice Have Increased Antitumor Immunity and Are Resistant to Experimental Metastasis (2011) (8)
- TLR7 Controls VSV Replication in CD169+ SCS Macrophages and Associated Viral Neuroinvasion (2019) (8)
- HIV Nef Expression Favors the Relative Preservation of CD4+ T Regulatory Cells That Retain Some Important Suppressive Functions (2014) (7)
- Epithelium‐specific MyD88 signaling, but not DCs or macrophages, control acute intestinal infection with Clostridium difficile (2018) (7)
- Osteopontin Promotes Protective Antigenic Tolerance against Experimental Allergic Airway Disease (2018) (7)
- Loss of the TGF beta-activating integrin alpha v beta 8 on dendritic cells protects mice from chronic intestinal parasitic infection via control of type 2 immunity (2013) (6)
- Administration of anti-CD25 mAb leads to impaired α-galactosylceramide-mediated induction of IFN-γ production in a murine model. (2013) (6)
- Dendritic cell metabolism: moving beyond in vitro-culture-generated paradigms. (2021) (5)
- regulatory T cells impairs mouse melanoma growth (2012) (5)
- Salmonella enterica Serovar Typhimurium Infection-Induced CD11b+ Gr1+ Cells Ameliorate Allergic Airway Inflammation (2013) (5)
- Multiple Layers of CD 80 / 86-Dependent Costimulatory Activity Regulate Primary , Memory , and Secondary Lymphocytic Choriomeningitis Virus-Specific T Cell Immunity (2012) (5)
- The Bcl 10 – Malt 1 complex segregates Fc ε RI-mediated nuclear factor κ B activation and cytokine production from mast cell degranulation (2006) (5)
- Structure‐Activity Relationship and Mode‐Of‐Action Studies Highlight 1‐(4‐Biphenylylmethyl)‐1H‐imidazole‐Derived Small Molecules as Potent CYP121 Inhibitors (2021) (5)
- Absence of Foxp 3 + Regulatory T Cells during Allergen Provocation Does Not Exacerbate Murine Allergic Airway Inflammation (2012) (5)
- Inflammation in the Human Periodontium Induces Downregulation of the α1- and β1-Subunits of the sGC in Cementoclasts (2021) (5)
- Regulatory T Cells (2017) (5)
- Assessing the suppressive activity of Foxp3⁺ regulatory T cells. (2014) (5)
- Dendritic Cell Homeostasis Is Maintained by Non-Hematopoietic and T Cell-Produced Flt3-Ligand In Steady-State and During Immune Responses. (2010) (4)
- Essential role of submandibular lymph node dendritic cells in protective sublingual immunotherapy against murine allergy (2020) (4)
- Adenoviral vector-mediated GM-CSF gene transfer improves anti-mycobacterial immunity in mice - role of regulatory T cells. (2017) (3)
- Transient Depletion of Foxp3+ Regulatory T Cells Selectively Promotes Aggressive β Cell Autoimmunity in Genetically Susceptible DEREG Mice (2021) (3)
- pDCs Take a Deep Breath to Fight Viruses. (2016) (3)
- Erratum: De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells (2015) (3)
- The Innate Immune Response to Infection Induces Erythropoietin-Dependent Replenishment of the Dendritic Cell Compartment (2020) (3)
- CCL19-Cre transgenics: targeting lymph node fibroblastic reticular cells in vivo (44.14) (2012) (2)
- Corrigendum: Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies (2009) (2)
- γδ T cells license immature B cells to produce a broad range of polyreactive antibodies. (2022) (2)
- Selective depletion of Foxp3+ regulatory T cells during sensitization phase aggravates experimental allergic airway inflammation (2010) (2)
- STING is an intrinsic checkpoint inhibitor that restrains the TH17 cell pathogenic program (2022) (2)
- Abstract LB-260: Combination of Foxp3+ T cells depletion and mTOR inhibitor enhances immune memory and controls cancer growth (2014) (2)
- Clarithromycin impairs tissue-resident memory and Th17 responses to macrolide-resistant Streptococcus pneumoniae infections (2021) (2)
- leukemia B cells production, and an immunogenic phenotype in chronic lymphocytic Immunostimulatory CpG-oligonucleotides cause proliferation, cytokine (2013) (1)
- Guidelines for mouse and human DC generation. (2022) (1)
- FcεRI-mediated nuclear factor κB activation and cytokine production from mast cell degranulation (2006) (1)
- mice by inducing dysfunction of the cerebral microvasculature Regulatory T cells are strong promoters of acute ischemic stroke in (2013) (1)
- Superagonistic CD28 stimulation induces IFN‐γ release from mouse T helper 1 cells in vitro and in vivo (2020) (1)
- Tspan2 is involved in anti-infectious immune responses and CNS autoimmunity (2020) (1)
- Activation-Induced Cell Death in Regulatory Expression Confers Resistance to Foxp 3-Mediated Suppression of CD 95 L (2011) (1)
- Correction: Selective depletion of Foxp3+ Treg during sensitization phase aggravates experimental allergic airway inflammation (2010) (1)
- Inhibiting fatty acid synthesis (FAS) can prevent and treat chronic graft versus host disease (cGVHD) (2020) (1)
- Targeting cellular fatty acid synthesis limits T helper and innate lymphoid cell function during intestinal inflammation and infection (2020) (1)
- Superior Suppressive Capacity of Skin Tregs Compared to Lung Tregs in a Model of Epicutaneous Priming. (2015) (1)
- mediated protective immunity (2013) (1)
- Efficient oral vaccination by bioengineering virus-like particles with protozoan surface proteins (2019) (1)
- Superior Suppressive Capacity of Skin Tregs Compared with Lung Tregs in a Model of Epicutaneous Priming. (2015) (1)
- Essential role of submandibular lymph node dendritic cells in protective sublingual immunotherapy against murine allergy (2020) (0)
- This information is current as Functions That Retain Some Important Suppressive T Regulatory Cells + Preservation of CD 4 HIV Nef Expression Favors the Relative and (2014) (0)
- Natural Regulatory T Cell Controls Physiological Tolerance And Regional Immune Privilege: Studies on (C57BL/6xA/J) F1 (B6AF1) DEREG (“depletion of regulatory T cell”) Mice (171.9) (2012) (0)
- Regulatory T cells session 2 (WS-045b) Chairpersons: Naganari Ohkura, Takayuki Yoshimoto (2010) (0)
- Metabolites: deciphering the molecular language between DCs and their environment (2016) (0)
- Recognition of Intact Donor Class I by Recipient CD8+ T Cells is Required for Tolerance Induction Following Liver-Directed Transgene Expression (2017) (0)
- The Innate Immune Response to Infection Induces Erythropoietin-Dependent Replenishment of the Dendritic Cell (2020) (0)
- A Key Role for Tregs in Renal Allograft Survival: Specific Deletion of Tregs in DEREG Mice Breaks Tolerance in Renal Transplants in the Murine DBA/2 to C57BL/6 Model: 969 (2012) (0)
- Advantages of Foxp 3 + regulatory T cell depletion using DEREG mice Advantages of Foxp 3 + regulatory T cell depletion (2014) (0)
- Lo Re Supplement.Material (2013) (0)
- Schistosome-induced pulmonary B cells inhibit allergic airway inflammation and display a reduced Th2-driving function (2015) (0)
- Abstract: 150 SELECTIVE DEPLETION OF FOXP3+ REGULATORY T CELLS EXACERBATES EXPERIMENTAL ATHEROSCLEROSIS IN MICE (2009) (0)
- The role of regulatory T cells in the Leishmania (Viannia) panamensis mouse model: a target for immunotherapy. (P3091) (2013) (0)
- Parasite Clearance in BALB/c Mice That Interfere with Immune Response and Regulatory T Cells + Expansion of Foxp3 Infection Induces Strongyloides ratti (2011) (0)
- Epithelium-specific MyD88 signaling, but not DCs or macrophages, control acute intestinal infection with Clostridium difficile (2019) (0)
- Regulatory T cells (PP-045) (2010) (0)
- Author response for "Superagonistic CD28 stimulation induces Interferon γ release from mouse T Helper 1 cells in vitro and in vivo" (2020) (0)
- into Th2 Cells during Helminth Infection Rapid In Vivo Conversion of Effector T Cells (2011) (0)
- IMMUNE CELLS SENSE PATHOGENS VIA DNA‐MOTIFS: INDUCTION OF LETHAL TOXIC SHOCK: 166 (1997) (0)
- Mouse Cytomegalovirus infection overrules T regulatory cell suppression on natural killer cells (2014) (0)
- T-regs Muscle In on the Action (2014) (0)
- transplantation regulatory T cells after experimental allogeneic bone marrow + FoxP3 + Identification and expansion of highly suppressive CD8 (2013) (0)
- Guidelines for mouse and human DC functional assays. (2022) (0)
- Regulatory T cells control the clinical expression of viral immunopathology by acting at both the lesion site and draining lymphoid tissue (170.9) (2012) (0)
- Retraction statement: Steatohepatitis as impaired immune metabolism induced by liver‐resident regulatory T‐cell depletion (2015) (0)
- Plasmodium yoelii IL-10 on Pathogen Clearance during Cells and Limited Effect of T Cell-Derived Regulatory T + Foxp 3 + Strong Impact of CD 4 (2012) (0)
- Viral Central Nervous System Infection Immune Privilege of Self-Antigens during Regulatory T Cells Selectively Preserve and Burkhard Ludewig (2012) (0)
- Tumor immunity and immunosurveillance (PP-093) (2010) (0)
- Influencing immune cell differentiation by microbe-associated immunomodulatory metabolites (meta-MAMPs) (2016) (0)
- Immunity to virus infection (excluding retroviruses) 2 (WS-025b) Chairpersons: Tsukasa Seya, Iain Campbell (2010) (0)
- Regulation of Toll-like Receptor Dusp 16 / MKP-7 in Perinatal Survival and Function of Dual Specificity Phosphatase Gene Trap Mice Reveal an Essential Signal Transduction : (2014) (0)
- Regulatory T cells in endogenous mouse lymphoma are antigen-specific nTregs and provide a target for immune checkpoint-inhibiting therapies (2018) (0)
- by Regulatory T Cells Immunostimulatory RNA Blocks Suppression (2009) (0)
- Production b of IFN-Plasmacytoid Dendritic Cells and Regulation Phosphatase Dusp9/MKP-4 in Mouse Selective Expression of the MAPK (2015) (0)
- CAN-10-1736 Cancer esearch oenvironment and Immunology ctive Depletion of Foxp 3 + Regulatory T Cells roves Effective Therapeutic Vaccination R inst Established Melanoma (2010) (0)
- 03.16 Regulatory t cells restrain autophagy in dendritic cells to ameliorate autoimmunity in a ctla4 dependent fashion (2017) (0)
- The TGF beta-activating integrin alpha v beta 8 on dendritic cells regulates type 2 immunity in the intestine to promote chronic parasitic infection (2013) (0)
- Production in Natural Scurfy Mutant Mice Defective Control of Th2 Cytokine Nonfunctional Regulatory T Cells and (2009) (0)
- This information is current as-Defensin β Induction of Regulatory T Cells by a Murine (2011) (0)
- Immune mechanisms mediated by Salmonella in ameliorating airway inflammation (P6031) (2013) (0)
- Regulation of immunity during viral lung infection (2011) (0)
- Regulatory T cells control the clinical expression of viral immunopathology by acting at both the lesion site and draining lymphoid tissue (2012) (0)
- Characterization of tetraspanin-2 expressing cells in the mouse (2014) (0)
- Tumor immunity and immunosurveillance, session 1 (WS-093a) Chairpersons: Kazuyoshi Takeda, Bruce Robinson (2010) (0)
- Role of regulatory T-cells (Tregs) in bacterial infection-induced lung fibrosis exacerbation in mice (2018) (0)
- Running title : Treg and Th 17 cells : a special relationship The special relationship in the development and function of T helper 17 and regulatory T cells (2016) (0)
- 90 FOXP3+ CD4+ REGULATORY T-CELLS MITIGATE IMMUNE RESPONSES AND TISSUE DAMAGE IN A MURINE MODEL OF ACUTE HEPATITIS B VIRUS INFECTION (2010) (0)
- Mouse Model of Lung Rejection Trafficking Enhances Tolerance Induction in a T Cell + Inhibiting CXCR3-Dependent CD8 (2011) (0)
- WS-093 a Tumor immunity and immunosurveillance 1 (2010) (0)
- Correction: TGFβ-activation by dendritic cells drives Th17 induction and intestinal contractility and augments the expulsion of the parasite Trichinella spiralis in mice (2021) (0)
- Combination of nanoparticle-based therapeutic vaccination and transient ablation of regulatory T cells enhances anti-viral immunity during chronic retroviral infection (2016) (0)
- Foxp3-independent suppression of autoimmunity by anti-CD4-induced recessive tolerization of autoreactive T cells (P5222) (2013) (0)
- Melanoma Effective Therapeutic Vaccination against Established Regulatory T Cells Improves + Selective Depletion of Foxp 3 Updated (2010) (0)
- Regulatory T cells control CNS-infiltration of autoreactive T cells during viral infection without affecting the antiviral immune response (2010) (0)
- CD 8 1 Foxp 3 1 T cells share developmental and phenotypic features with classical CD 4 1 Foxp 3 1 regulatory T cells but lack potent suppressive activity (2015) (0)
- Erratum: Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies (Nature Medicine (2009) 15 (528-536)) (2009) (0)
- 372 SELECTIVE DEPLETION OF T REGULATORY CELLS IMPACTS EXPERIMENTAL ATHEROSCLEROSIS PROGRESSION AND VLDL METABOLISM (2011) (0)
- Regulation of DC metabolism by nitric oxide in murine GM‐CSF cultures (2022) (0)
- Viral-Induced Inflammatory Lesions On the Role of Regulatory T Cells during (2013) (0)
- Vaccination and immunotherapy of viral diseases (WS-069) Chairpersons: Tetsuro Matano, Rene van Lier (2010) (0)
- Antibodies to variable surface antigens induce antigenic variation in the intestinal parasite Giardia lamblia (2023) (0)
- MP35-17 COMBINATION OF MTOR INHIBITION AND CD4 DEPLETION GENERATES ANTITUMOR IMMUNITY (2014) (0)
- Responsesof Th1 Predisposition to Antigen-Driven Lymphadenopathy Is Associated with a State CpG-DNA-Mediated Transient (2000) (0)
- Th1/Th2 (PP-015) (2010) (0)
- Infection Staphylococcus aureus during Regulatory T Cells in Immunosuppression Suppressor Cells and a Minor Role for A Major Role for Myeloid-Derived (2014) (0)
- melanoma-bearing mice macrophages in both untreated and B16 + (2012) (0)
- Infection Leishmania (Viannia) panamensis T Cells in The Immunotherapeutic Role of Regulatory (2014) (0)
- The TGFβ-activating integrin αvβ8 on dendritic cells regulates type 2 immunity in the intestine to promote chronic parasitic infection (P3318) (2013) (0)
- Regulatory T cells control CNS-infiltration of autoreactive T cells during viral infection without affecting the antiviral immune response (83.24) (2010) (0)
- Regulation of immunity during viral lung infection (168.1) (2011) (0)
- 96: PD-L1hi B regulatory cells are critical for control of the humoral immune response (2014) (0)
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