Tim Spector

Q: What Schools Are Affiliated With Tim Spector

Tim Spector is affiliated with the following schools: Uppsala University, University of East Anglia, Vrije Universiteit Amsterdam, University of Oxford, University of Wollongong, University of Aberdeen, King's College London, University of Helsinki, King's College, Aberdeen

Tim Spector's AcademicInfluence.com Rankings

Tim Spector

Medical

#142

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#219

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Epidemiology

#26

World Rank

#30

Historical Rank

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Why Is Tim Spector Influential?

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According to Wikipedia, Timothy David Spector is a British epidemiologist, medical doctor, and science writer. Biography Spector was born in North London in July 1958. He trained in medicine and rose to the position of consultant rheumatologist, before turning to genetic epidemiology, the study of genetic factors in health and disease, in 1992.

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Tim Spector's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Genetic studies of body mass index yield new insights for obesity biology (2015) (3549)
Biological, Clinical, and Population Relevance of 95 Loci for Blood Lipids (2010) (3485)
Epigenetic differences arise during the lifetime of monozygotic twins. (2005) (3392)
Discovery and Refinement of Loci Associated with Lipid Levels (2013) (2475)
Osteoarthritis: New Insights. Part 1: The Disease and Its Risk Factors (2000) (2404)
Human Genetics Shape the Gut Microbiome (2014) (2191)
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (2010) (2087)
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index (2010) (2011)
Hundreds of variants clustered in genomic loci and biological pathways affect human height (2010) (1961)
Genetic Variants in Novel Pathways Influence Blood Pressure and Cardiovascular Disease Risk (2011) (1928)
Defining the role of common variation in the genomic and biological architecture of adult human height (2014) (1805)
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation (2009) (1735)
The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis. (2004) (1573)
Risk of COVID-19 among front-line health-care workers and the general community: a prospective cohort study (2020) (1279)
New genetic loci link adipose and insulin biology to body fat distribution (2014) (1227)
Genome-wide association study identifies eight loci associated with blood pressure (2009) (1225)
Association analyses of 249,796 individuals reveal eighteen new loci associated with body mass index (2010) (1179)
Common genetic determinants of vitamin D insufficiency: a genome-wide association study (2010) (1177)
Attributes and predictors of long COVID (2021) (1166)
Genome-wide association study identifies 74 loci associated with educational attainment (2016) (1114)
Real-time tracking of self-reported symptoms to predict potential COVID-19 (2020) (1089)
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture (2012) (1045)
Obesity, cigarette smoking, and telomere length in women (2005) (1028)
Human metabolic individuality in biomedical and pharmaceutical research (2011) (929)
The genetic architecture of type 2 diabetes (2016) (927)
The UK10K project identifies rare variants in health and disease (2015) (926)
An atlas of genetic influences on human blood metabolites (2014) (913)
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts (2009) (909)
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution (2010) (897)
Causal Relationship between Obesity and Vitamin D Status: Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts (2013) (892)
Genetic control of the circulating concentration of transforming growth factor type beta1. (1999) (774)
Common variants associated with plasma triglycerides and risk for coronary artery disease (2013) (767)
Identification of seven loci affecting mean telomere length and their association with disease (2013) (761)
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways (2012) (758)
Mapping cis- and trans-regulatory effects across multiple tissues in twins (2012) (754)
Variants in MTNR1B influence fasting glucose levels (2009) (742)
Modulation of Genetic Associations with Serum Urate Levels by Body-Mass-Index in Humans (2015) (724)
Genetic Determinants of the Gut Microbiome in UK Twins. (2016) (714)
Role of the gut microbiota in nutrition and health (2018) (712)
Genetic influences on osteoarthritis in women: a twin study (1996) (704)
DNA methylation-based measures of biological age: meta-analysis predicting time to death (2016) (699)
Sequence variants at CHRNB3–CHRNA6 and CYP2A6 affect smoking behavior (2010) (688)
Twenty bone mineral density loci identified by large-scale meta-analysis of genome-wide association studies (2009) (687)
Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains. (2010) (680)
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations (2012) (678)
DNA methylation and body-mass index: a genome-wide analysis (2014) (664)
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (2018) (659)
Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study (2008) (658)
Epigenome-Wide Scans Identify Differentially Methylated Regions for Age and Age-Related Phenotypes in a Healthy Ageing Population (2012) (649)
Heritability of adult body height: a comparative study of twin cohorts in eight countries. (2003) (644)
A genome-wide perspective of genetic variation in human metabolism (2010) (639)
A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease (2011) (638)
Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity (2016) (634)
Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations (2009) (617)
Vaccine side-effects and SARS-CoV-2 infection after vaccination in users of the COVID Symptom Study app in the UK: a prospective observational study (2021) (588)
Proton pump inhibitors alter the composition of the gut microbiota (2015) (577)
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture (2013) (568)
Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses (2016) (563)
Genome-wide association study identifies five loci associated with lung function (2010) (560)
Obesity accelerates epigenetic aging of human liver (2014) (557)
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium (2009) (551)
Host genetic variation impacts microbiome composition across human body sites (2015) (540)
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study (2015) (532)
The association between physical activity in leisure time and leukocyte telomere length. (2008) (531)
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma (2011) (526)
Genetic influences on cervical and lumbar disc degeneration: a magnetic resonance imaging study in twins. (1999) (519)
Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution (2009) (516)
Rare and low-frequency coding variants alter human adult height (2016) (511)
Parent-of-origin specific allelic associations among 106 genomic loci for age at menarche (2014) (511)
Physical Activity Attenuates the Influence of FTO Variants on Obesity Risk: A Meta-Analysis of 218,166 Adults and 19,268 Children (2011) (508)
Predicting brain age with deep learning from raw imaging data results in a reliable and heritable biomarker (2016) (504)
A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15 (2007) (498)
American Gut: an Open Platform for Citizen Science Microbiome Research (2018) (496)
Risk factors for osteoarthritis: genetics. (2004) (481)
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies (2010) (477)
Meta-Analysis of Genome-Wide Association Studies in >80 000 Subjects Identifies Multiple Loci for C-Reactive Protein Levels (2011) (476)
The relationship of obesity, fat distribution and osteoarthritis in women in the general population: the Chingford Study. (1993) (462)
The Architecture of Gene Regulatory Variation across Multiple Human Tissues: The MuTHER Study (2011) (460)
Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals (2012) (459)
Genes and environment in refractive error: the twin eye study. (2001) (459)
Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia. (2008) (450)
Exome-wide association study of plasma lipids in >300,000 individuals (2017) (428)
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk (2017) (428)
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure (2011) (424)
New gene functions in megakaryopoiesis and platelet formation (2011) (423)
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences (2019) (421)
Genetic Influences on Muscle Strength, Lean Body Mass, and Bone Mineral Density: A Twin Study (1997) (419)
Erratum: Detection and interpretation of shared genetic influences on 42 human traits (2016) (417)
Is the Tendency to Engage in Entrepreneurship Genetic? (2008) (411)
FTO genotype is associated with phenotypic variability of body mass index (2012) (407)
Incidence and risk factors for radiographic knee osteoarthritis in middle-aged women: the Chingford Study. (1999) (407)
The association of obesity with osteoarthritis of the hand and knee in women: a twin study. (1996) (402)
The heritability of bone mineral density, ultrasound of the calcaneus and hip axis length: A study of postmenopausal twins (1996) (402)
Genome-wide association and large scale follow-up identifies 16 new loci influencing lung function (2011) (401)
Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture (2015) (399)
Low-level increases in serum C-reactive protein are present in early osteoarthritis of the knee and predict progressive disease. (1997) (395)
A structural variation reference for medical and population genetics (2020) (394)
Genes control the cessation of a woman's reproductive life: a twin study of hysterectomy and age at menopause. (1998) (390)
Risk of osteoarthritis associated with long-term weight-bearing sports: a radiologic survey of the hips and knees in female ex-athletes and population controls. (1996) (390)
Is low birth weight an antecedent of CKD in later life? A systematic review of observational studies. (2009) (388)
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function (2016) (388)
Lipidomics Profiling and Risk of Cardiovascular Disease in the Prospective Population-Based Bruneck Study (2014) (386)
The fecal metabolome as a functional readout of the gut microbiome (2018) (386)
The assessment of vertebral deformity: A method for use in population studies and clinical trials (1993) (384)
Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study (2012) (382)
Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia (2013) (379)
Meta-analysis of telomere length in 19 713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect (2013) (375)
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium (2009) (369)
Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits (2013) (365)
Risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression in patients with medial compartment osteoarthritis of the knee: results of the two-year multinational knee osteoarthritis structural arthritis study. (2006) (364)
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk (2017) (359)
Gender and telomere length: Systematic review and meta-analysis (2014) (359)
Seventy-five genetic loci influencing the human red blood cell (2012) (357)
Multi-ethnic genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis (2015) (356)
Lumbar disc degeneration and genetic factors are the main risk factors for low back pain in women: the UK Twin Spine Study (2011) (354)
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals (2016) (347)
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction (2010) (345)
Novel Associations of Multiple Genetic Loci With Plasma Levels of Factor VII, Factor VIII, and von Willebrand Factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium (2010) (344)
Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements. (2013) (341)
A twin approach to unraveling epigenetics (2011) (338)
Biomarkers for Type 2 Diabetes and Impaired Fasting Glucose Using a Nontargeted Metabolomics Approach (2013) (338)
Gut microbiota associations with common diseases and prescription medications in a population-based cohort (2018) (332)
Interleukin-6 is a significant predictor of radiographic knee osteoarthritis: The Chingford study (2009) (330)
The effects of social status on biological aging as measured by white‐blood‐cell telomere length (2006) (325)
Interplay between the human gut microbiome and host metabolism (2019) (325)
META-ANALYSIS OF GENOME-WIDE ASSOCIATION STUDIES IDENTIFIES THREE NEW RISK LOCI FOR ATOPIC DERMATITIS (2011) (325)
The relationship between osteoarthritis and osteoporosis in the general population: the Chingford Study. (1994) (322)
Intergenic variants of HBS1L-MYB are responsible for a major quantitative trait locus on chromosome 6q23 influencing fetal hemoglobin levels in adults (2007) (319)
Common variants near TERC are associated with mean telomere length (2010) (318)
Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study (2014) (318)
Rapid implementation of mobile technology for real-time epidemiology of COVID-19 (2020) (317)
GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability (2018) (316)
Identification of an imprinted master trans-regulator at the KLF14 locus related to multiple metabolic phenotypes (2011) (316)
The human gut and groundwater harbor non-photosynthetic bacteria belonging to a new candidate phylum sibling to Cyanobacteria (2013) (316)
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile (2011) (313)
Sequence variants at CHRNB 3 – CHRNA 6 and CYP 2 A 6 affect smoking behavior (2010) (312)
Are twins and singletons comparable? A study of disease-related and lifestyle characteristics in adult women. (2001) (309)
Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis (2017) (308)
Large-scale genomic analyses link reproductive ageing to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair (2015) (308)
The genetics of haemostasis: a twin study (2001) (307)
Incidence and progression of osteoarthritis in women with unilateral knee disease in the general population: the effect of obesity. (1994) (304)
Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study (2017) (302)
Risk factors and disease profile of post-vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: a prospective, community-based, nested, case-control study (2021) (301)
A Genome-Wide Association Study Identifies Five Loci Influencing Facial Morphology in Europeans (2012) (300)
Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders (2013) (299)
Effect of Diet on the Gut Microbiota: Rethinking Intervention Duration (2019) (298)
Evidence for increased bone resorption in patients with progressive knee osteoarthritis: longitudinal results from the Chingford study. (2002) (298)
Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel (2015) (296)
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes (2017) (294)
Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci. (2015) (291)
Genetic influences on F cells and other hematologic variables: a twin heritability study. (2000) (290)
Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation (2014) (287)
Signatures of early frailty in the gut microbiota (2016) (286)
Inherited Variation in Vitamin D Genes Is Associated With Predisposition to Autoimmune Disease Type 1 Diabetes (2011) (286)
Genome-Wide Association Study of Blood Pressure Extremes Identifies Variant near UMOD Associated with Hypertension (2010) (285)
Association between metabolic factors and knee osteoarthritis in women: the Chingford Study. (1995) (284)
Structural, psychological, and genetic influences on low back and neck pain: a study of adult female twins. (2004) (282)
A Comprehensive Evaluation of Potential Lung Function Associated Genes in the SpiroMeta General Population Sample (2011) (281)
Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus (2013) (279)
Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals (2021) (277)
Meta-analysis of genome-wide association data identifies two loci influencing age at menarche (2009) (276)
Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism (2015) (276)
Whole-genome sequencing identifies common-to-rare variants associated with human blood metabolites (2017) (275)
Human postprandial responses to food and potential for precision nutrition (2020) (273)
The UK Adult Twin Registry (TwinsUK) (2006) (272)
Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption (2011) (270)
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors (2018) (269)
Quantitative variability of 342 plasma proteins in a human twin population (2015) (269)
Genetics of osteoporosis from genome-wide association studies: advances and challenges (2012) (268)
Collaborative Meta-analysis: Associations of 150 Candidate Genes With Osteoporosis and Osteoporotic Fracture (2009) (267)
Genetic loci influencing kidney function and chronic kidney disease (2010) (266)
Genome-Wide Association Study Using Extreme Truncate Selection Identifies Novel Genes Affecting Bone Mineral Density and Fracture Risk (2011) (262)
Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization (2014) (260)
Genetic Contribution to Bone Metabolism, Calcium Excretion, and Vitamin D and Parathyroid Hormone Regulation (2001) (259)
Definition of osteoarthritis of the knee for epidemiological studies. (1993) (258)
Genetic Influences on Exercise Participation in 37.051 Twin Pairs from Seven Countries (2006) (258)
WNT16 Influences Bone Mineral Density, Cortical Bone Thickness, Bone Strength, and Osteoporotic Fracture Risk (2012) (257)
The UK Adult Twin Registry (TwinsUK Resource) (2012) (256)
A high incidence of vertebral fracture in women with breast cancer (1999) (255)
Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B.1.1.7: an ecological study (2021) (254)
Symptom prevalence, duration, and risk of hospital admission in individuals infected with SARS-CoV-2 during periods of omicron and delta variant dominance: a prospective observational study from the ZOE COVID Study (2022) (253)
Mapping genetic loci that determine leukocyte telomere length in a large sample of unselected female sibling pairs. (2006) (251)
Offspring's Leukocyte Telomere Length, Paternal Age, and Telomere Elongation in Sperm (2008) (250)
Genome-wide analysis identifies 12 loci influencing human reproductive behavior (2016) (250)
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals (2018) (249)
Gut microbiome diversity and high-fibre intake are related to lower long-term weight gain (2017) (248)
Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial (2012) (248)
Meta-Analysis of Genome-Wide Scans for Human Adult Stature Identifies Novel Loci and Associations with Measures of Skeletal Frame Size (2009) (247)
Human serum metabolic profiles are age dependent (2012) (247)
Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology (2010) (247)
Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels (2018) (246)
Glycans Are a Novel Biomarker of Chronological and Biological Ages (2013) (245)
Genetic epidemiology of hip and knee osteoarthritis (2011) (245)
Cohort Profile: TwinsUK and healthy ageing twin study. (2013) (244)
Effect of risedronate on joint structure and symptoms of knee osteoarthritis: results of the BRISK randomized, controlled trial [ISRCTN01928173] (2005) (244)
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk (2016) (242)
Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria (2018) (241)
Genetic influences in gastro-oesophageal reflux disease: a twin study (2003) (240)
Genetic influence on early age-related maculopathy: a twin study. (2002) (239)
Higher anthocyanin intake is associated with lower arterial stiffness and central blood pressure in women. (2012) (238)
Gene expression changes with age in skin, adipose tissue, blood and brain (2013) (237)
A DNA methylation biomarker of alcohol consumption (2016) (236)
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension (2016) (234)
The Genetic Architecture of the Human Immune System: A Bioresource for Autoimmunity and Disease Pathogenesis (2015) (232)
Risk of vertebral fracture in women with rheumatoid arthritis. (1993) (232)
Genetic and environmental factors in age-related nuclear cataracts in monozygotic and dizygotic twins. (2000) (231)
Are Twins and Singletons Comparable? A Study of Disease-related and Lifestyle Characteristics in Adult Women (2001) (230)
Serum adiponectin and bone mineral density in women. (2007) (227)
Low copy number of the salivary amylase gene predisposes to obesity (2014) (224)
Population genetic differentiation of height and body mass index across Europe (2015) (224)
The association between hip morphology parameters and nineteen-year risk of end-stage osteoarthritis of the hip: A nested case–control study (2011) (223)
Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi (2009) (223)
Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders. (2018) (221)
Shotgun Metagenomics of 250 Adult Twins Reveals Genetic and Environmental Impacts on the Gut Microbiome. (2016) (221)
Bone mineral density and vertebral compression fracture rates in ankylosing spondylitis. (1994) (220)
Effect of hormone replacement therapy on bone mass in rheumatoid arthritis patients treated with and without steroids. (1994) (220)
Loss of smell and taste in combination with other symptoms is a strong predictor of COVID-19 infection (2020) (218)
A Genome-Wide Association Meta-Analysis of Circulating Sex Hormone–Binding Globulin Reveals Multiple Loci Implicated in Sex Steroid Hormone Regulation (2012) (216)
Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight. (2016) (214)
Sex and ethnic differences in the association of ASPN, CALM1, COL2A1, COMP, and FRZB with genetic susceptibility to osteoarthritis of the knee. (2007) (214)
An Integration of Genome-Wide Association Study and Gene Expression Profiling to Prioritize the Discovery of Novel Susceptibility Loci for Osteoporosis-Related Traits (2010) (213)
Illness duration and symptom profile in symptomatic UK school-aged children tested for SARS-CoV-2 (2021) (212)
Genome-wide analysis of multiethnic cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma (2014) (212)
Attributes and predictors of Long-COVID: analysis of COVID cases and their symptoms collected by the Covid Symptoms Study App (2020) (212)
The genetic contribution to radiographic hip osteoarthritis in women: results of a classic twin study. (2000) (211)
A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22. (2010) (210)
The Three-Factor Eating Questionnaire, body mass index, and responses to sweet and salty fatty foods: a twin study of genetic and environmental associations. (2008) (210)
Higher serum vitamin D concentrations are associated with longer leukocyte telomere length in women. (2007) (210)
Metabolomic markers reveal novel pathways of ageing and early development in human populations (2013) (209)
A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14 (2010) (208)
A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25 (2010) (207)
A susceptibility locus for myopia in the normal population is linked to the PAX6 gene region on chromosome 11: a genomewide scan of dizygotic twins. (2004) (207)
Large-scale association analyses identify host factors influencing human gut microbiome composition (2020) (206)
Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand. (2009) (203)
The influence of genetics and environmental factors in the pathogenesis of acne: a twin study of acne in women. (2002) (201)
Intakes of anthocyanins and flavones are associated with biomarkers of insulin resistance and inflammation in women. (2014) (201)
Risk of COVID-19 among frontline healthcare workers and the general community: a prospective cohort study (2020) (200)
Genetic evidence of assortative mating in humans (2017) (199)
The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis (2013) (199)
Association of Systemic Lupus Erythematosus With Decreased Immunosuppressive Potential of the IgG Glycome (2015) (198)
The association of body mass index and osteoarthritis of the knee joint: an examination of genetic and environmental influences. (2003) (198)
KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference (2016) (198)
HbA(1c) levels are genetically determined even in type 1 diabetes: evidence from healthy and diabetic twins. (2001) (197)
Obesity Is an Important Determinant of Baseline Serum C-Reactive Protein Concentration in Monozygotic Twins, Independent of Genetic Influences (2004) (197)
Is hormone replacement therapy protective for hand and knee osteoarthritis in women?: The Chingford study (1997) (197)
Effect of spinal osteophytosis on bone mineral density measurements in vertebral osteoporosis. (1993) (196)
Effects of long-term strontium ranelate treatment on the risk of nonvertebral and vertebral fractures in postmenopausal osteoporosis: Results of a five-year, randomized, placebo-controlled trial. (2008) (195)
Influence of vitamin D receptor genotype on bone mineral density in postmenopausal women: a twin study in Britain (1995) (194)
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure underpinning obesity (2017) (193)
A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function (2013) (193)
The autosomal dominant hypophosphatemic rickets (ADHR) gene is a secreted polypeptide overexpressed by tumors that cause phosphate wasting. (2001) (192)
Klotho Gene Polymorphisms Associated With Bone Density of Aged Postmenopausal Women (2002) (191)
Association study of candidate genes for the prevalence and progression of knee osteoarthritis. (2004) (189)
The effect of rheumatoid arthritis and steroid therapy on bone density in postmenopausal women. (1993) (187)
Digital Quantification of Human Eye Color Highlights Genetic Association of Three New Loci (2010) (187)
Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study (2011) (185)
A mutation in COL9A1 causes multiple epiphyseal dysplasia: further evidence for locus heterogeneity. (2001) (184)
Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans (2012) (184)
Profound Perturbation of the Metabolome in Obesity Is Associated with Health Risk (2019) (183)
Gene-gene and gene-environment interactions detected by transcriptome sequence analysis in twins (2014) (183)
Association of pain with radiological changes in different compartments and views of the knee joint. (1996) (182)
Heritability of responses to painful stimuli in women: a classical twin study. (2007) (181)
Reproducible genetic associations between candidate genes and clinical knee osteoarthritis in men and women. (2006) (180)
Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis (2012) (180)
Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels (2015) (179)
Genome-Wide Linkage Scan for Athlete Status in 700 British Female DZ Twin Pairs (2007) (179)
Human telomere biology: pitfalls of moving from the laboratory to epidemiology. (2006) (179)
Risk factors for progression of lumbar spine disc degeneration: the Chingford Study. (2003) (179)
Heritable components of the human fecal microbiome are associated with visceral fat (2016) (179)
The relationship of bone density and fracture to incident and progressive radiographic osteoarthritis of the knee: the Chingford Study. (2002) (178)
Association of JAG1 with bone mineral density and osteoporotic fractures: a genome-wide association study and follow-up replication studies. (2010) (178)
cMYB is involved in the regulation of fetal hemoglobin production in adults. (2006) (175)
The heritability of age-related cortical cataract: the twin eye study. (2001) (175)
Combined Genome Scans for Body Stature in 6,602 European Twins: Evidence for Common Caucasian Loci (2007) (175)
Heritability of Clot Formation, Morphology, and Lysis: The EuroCLOT Study (2007) (172)
The GDF5 rs143383 polymorphism is associated with osteoarthritis of the knee with genome-wide statistical significance (2010) (172)
Radiological progression of osteoarthritis: an 11 year follow up study of the knee. (1992) (172)
Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects. (2018) (171)
The coupling of bone and cartilage turnover in osteoarthritis: opportunities for bone antiresorptives and anabolics as potential treatments? (2013) (171)
Genetic variation in the SMAD3 gene is associated with hip and knee osteoarthritis. (2010) (170)
Radiographic assessment of osteoarthritis in population studies: whither Kellgren and Lawrence? (1993) (169)
Genetic effects on baseline values of C-reactive protein and serum amyloid a protein: a comparison of monozygotic and dizygotic twins. (2004) (169)
Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals. (2010) (168)
Genome-Wide Joint Meta-Analysis of SNP and SNP-by-Smoking Interaction Identifies Novel Loci for Pulmonary Function (2012) (167)
A Genome-Wide Association Study Reveals Variants in ARL15 that Influence Adiponectin Levels (2009) (164)
Hippurate as a metabolomic marker of gut microbiome diversity: Modulation by diet and relationship to metabolic syndrome (2017) (164)
DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker (2012) (164)
Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) study. (2016) (164)
Identification of Novel Genetic Loci Associated with Thyroid Peroxidase Antibodies and Clinical Thyroid Disease (2014) (163)
Meta‐Analysis of Genome‐Wide Scans Provides Evidence for Sex‐ and Site‐Specific Regulation of Bone Mass (2006) (161)
Twins. Novel uses to study complex traits and genetic diseases. (2000) (160)
Association between birth weight and adult blood pressure in twins: historical cohort study (1999) (159)
Epigenetics of discordant monozygotic twins: implications for disease (2014) (159)
Genetics (AAGC) (2015). Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis. (2015) (157)
The pill, parity, and rheumatoid arthritis. (1990) (157)
Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22 (2010) (156)
Menopause modifies the association of leukocyte telomere length with insulin resistance and inflammation. (2006) (155)
Genome-wide association analysis identifies multiple loci related to resting heart rate. (2010) (154)
The Autosomal Dominant Hypophosphatemic Rickets (ADHR) Gene Is a Secreted Polypeptide Overexpressed by Tumors that Cause Phosphate Wasting (2001) (153)
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls (2019) (153)
DNA Methylation of Lipid-Related Genes Affects Blood Lipid Levels (2015) (153)
Genetic correlates of musical pitch recognition in humans. (2001) (152)
A reference map of potential determinants for the human serum metabolome (2020) (152)
Symptom clusters in COVID-19: A potential clinical prediction tool from the COVID Symptom Study app (2020) (152)
Serum branched-chain amino acid to histidine ratio: a novel metabolomic biomarker of knee osteoarthritis (2010) (152)
Development of musculoskeletal toxicity without clear benefit after administration of PG-116800, a matrix metalloproteinase inhibitor, to patients with knee osteoarthritis: a randomized, 12-month, double-blind, placebo-controlled study (2007) (151)
The Trans-Ancestral Genomic Architecture of Glycemic Traits (2020) (151)
Central corneal thickness is highly heritable: the twin eye studies. (2005) (151)
Subclinical deformities of the hip are significant predictors of radiographic osteoarthritis and joint replacement in women. A 20 year longitudinal cohort study. (2014) (151)
Human metabolic profiles are stably controlled by genetic and environmental variation (2011) (151)
Recent and lifelong sexual dysfunction in a female UK population sample: prevalence and risk factors. (2011) (150)
Predicting genome-wide DNA methylation using methylation marks, genomic position, and DNA regulatory elements (2013) (150)
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways (2012) (150)
Fear of falling limiting activity in young-old women is associated with reduced functional mobility rather than psychological factors. (2005) (149)
Gut microbial diversity is associated with lower arterial stiffness in women (2018) (149)
Meta-analyses identify 13 novel loci associated with age at menopause and highlights DNA repair and immune pathways (2011) (149)
Telomere length in leukocytes correlates with bone mineral density and is shorter in women with osteoporosis (2007) (149)
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits (2017) (149)
The genetic epidemiology of joint hypermobility: a population study of female twins. (2004) (148)
Prevalence of vertebral fracture in women and the relationship with bone density and symptoms: The chingford study (1993) (148)
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels (2016) (147)
Omega-3 fatty acids correlate with gut microbiome diversity and production of N-carbamylglutamate in middle aged and elderly women (2017) (146)
The contribution of genes to osteoarthritis. (2009) (146)
A Metabolome-Wide Association Study of Kidney Function and Disease in the General Population. (2016) (144)
Directional dominance on stature and cognition in diverse human populations (2015) (144)
Loci at chromosomes 13, 19 and 20 influence age at natural menopause (2009) (143)
Common Genetic Variants near the Brittle Cornea Syndrome Locus ZNF469 Influence the Blinding Disease Risk Factor Central Corneal Thickness (2010) (143)
Association of early osteoarthritis of the knee with a Taq I polymorphism of the vitamin D receptor gene. (1997) (143)
Genetics, the Big Five, and the tendency to be self-employed. (2010) (143)
Genetic influence on bone turnover in postmenopausal twins. (1996) (142)
Comparison of genome screens for two independent cohorts provides replication of suggestive linkage of bone mineral density to 3p21 and 1p36. (2003) (142)
Ischemic Stroke Is Associated with the ABO Locus: The EuroCLOT Study (2013) (142)
Menopause, oestrogens and arthritis. (2000) (141)
Genome-wide association analysis identifies six new loci associated with forced vital capacity (2014) (141)
Extended haplotypes and linkage disequilibrium in the IL1R1–IL1A–IL1B–IL1RN gene cluster: association with knee osteoarthritis (2004) (140)
EPHA2 Is Associated with Age-Related Cortical Cataract in Mice and Humans (2009) (140)
The effect of weight‐bearing exercise on bone mineral density: A study of female ex‐elite athletes and the general population (1996) (140)
A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB. (2009) (140)
Schmorl's nodes: common, highly heritable, and related to lumbar disc disease. (2007) (139)
Ageing, genes, environment and epigenetics: what twin studies tell us now, and in the future. (2012) (139)
A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals (2019) (139)
Genetics of risk factors for melanoma: an adult twin study of nevi and freckles. (2000) (138)
A variant in MCF2L is associated with osteoarthritis. (2011) (137)
Food neophobia shows heritable variation in humans (2007) (137)
The Molecular Genetic Architecture of Self-Employment (2013) (137)
Birthweight, vitamin D receptor genotype and the programming of osteoporosis. (2001) (136)
Genome-wide association study of smoking initiation and current smoking. (2009) (136)
Genome-wide association identifies ATOH7 as a major gene determining human optic disc size (2010) (136)
Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study (2016) (135)
Genome-wide association scan identifies a prostaglandin-endoperoxide synthase 2 variant involved in risk of knee osteoarthritis. (2008) (135)
Common variants in the region around Osterix are associated with bone mineral density and growth in childhood (2009) (135)
Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium (2016) (134)
Differential methylation of the TRPA1 promoter in pain sensitivity (2014) (133)
Differential methylation of the TRPA1 promoter in pain sensitivity (2014) (133)
Multiethnic Meta-Analysis of Genome-Wide Association Studies in >100 000 Subjects Identifies 23 Fibrinogen-Associated Loci but No Strong Evidence of a Causal Association Between Circulating Fibrinogen and Cardiovascular Disease (2013) (133)
DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation. (2017) (132)
A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip (2013) (132)
The genetic contribution to carpal tunnel syndrome in women: a twin study. (2002) (132)
Genetic and environmental influences on height from infancy to early adulthood: An individual-based pooled analysis of 45 twin cohorts (2016) (132)
Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study (2010) (131)
Virome Diversity Correlates with Intestinal Microbiome Diversity in Adult Monozygotic Twins. (2019) (131)
Corrigendum: TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport (2016) (131)
Meta-Analysis of Genome-Wide Association Studies Identifies Six New Loci for Serum Calcium Concentrations (2013) (130)
Relationship between bone mineral density changes and fracture risk reduction in patients treated with strontium ranelate. (2007) (130)
Genetics of skin color variation in Europeans: genome-wide association studies with functional follow-up (2015) (129)
Design and conduct of clinical trials in patients with osteoarthritis of the hand: recommendations from a task force of the Osteoarthritis Research Society International. (2006) (129)
Estimating heritability and shared environmental effects for refractive error in twin and family studies. (2009) (129)
Risk of Wrist Fracture in Women Is Heritable and Is Influenced by Genes That Are Largely Independent of Those Influencing BMD (2004) (129)
Estimating telomere length from whole genome sequence data (2014) (129)
Genetic and Environmental Influences on Total-Body and Central Abdominal Fat: The Effect of Physical Activity in Female Twins (1999) (129)
Genetic influences on variation in female orgasmic function: a twin study (2005) (129)
A Genome-Wide Metabolic QTL Analysis in Europeans Implicates Two Loci Shaped by Recent Positive Selection (2011) (129)
The power of genetic diversity in genome-wide association studies of lipids (2021) (129)
Kin recognition signals in adult faces (2009) (128)
Heritability of objectively assessed daily physical activity and sedentary behavior1234 (2013) (128)
Adiposity as a cause of cardiovascular disease: a Mendelian randomization study. (2015) (128)
Increased wave reflection rather than central arterial stiffness is the main determinant of raised pulse pressure in women and relates to mismatch in arterial dimensions: a twin study. (2009) (127)
Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM (2011) (127)
Large meta-analysis of genome-wide association studies identifies five loci for lean body mass (2017) (127)
IRF4 variants have age-specific effects on nevus count and predispose to melanoma. (2010) (126)
Prediction model for knee osteoarthritis incidence, including clinical, genetic and biochemical risk factors (2013) (126)
Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics (2018) (126)
Generalized osteoarthritis in women: pattern of joint involvement and approaches to definition for epidemiological studies. (1996) (126)
Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31 (2014) (125)
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation (2020) (125)
Generalised osteoarthritis: a hormonally mediated disease. (1989) (124)
A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function. (2009) (124)
The genetics of coronary heart disease: the contribution of twin studies. (2003) (124)
ADVANCES IN TWIN AND SIB-PAIR ANALYSIS (2004) (124)
Evidence of altered bone turnover, vitamin D and calcium regulation with knee osteoarthritis in female twins. (2003) (123)
Cigarette smoking and risk of osteoarthritis in women in the general population: the Chingford study. (1993) (123)
Multiple Loci Are Associated with White Blood Cell Phenotypes (2011) (123)
Genetic interactions affecting human gene expression identified by variance association mapping (2014) (122)
Genetic Influences in Irritable Bowel Syndrome: A Twin Study (2005) (122)
The role of pregnancy in the course and aetiology of rheumatoid arthritis (1992) (121)
Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney (2017) (121)
Biomarkers in osteoarthritis (2008) (120)
The association between osteoarthritis and osteoporotic fracture: the Chingford Study. (1996) (119)
OARSI-OMERACT definition of relevant radiological progression in hip/knee osteoarthritis. (2009) (119)
The Big Finger: the second to fourth digit ratio is a predictor of sporting ability in women (2006) (119)
The Ile585Val TRPV1 variant is involved in risk of painful knee osteoarthritis (2011) (119)
Recommendations for the registration of drugs used in the treatment of osteoarthritis. Group for the respect of ethics and excellence in science (GREES): osteoarthritis section. (1996) (119)
Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region (2012) (118)
A randomised controlled trial of the effect of hormone replacement therapy on disease activity in postmenopausal rheumatoid arthritis. (1994) (118)
Genetic influences in self-reported symptoms of obstructive sleep apnoea and restless legs: a twin study. (2004) (118)
Concordance and interrelationship of atopic diseases and markers of allergic sensitization among adult female twins. (2001) (118)
Opportunity recognition and the tendency to be an entrepreneur: A bivariate genetics perspective (2009) (118)
Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation (2018) (117)
Risk factors for osteoarthritis in the tibiofemoral and patellofemoral joints of the knee. (1997) (117)
Dietary Patterns and Heritability of Food Choice in a UK Female Twin Cohort (2007) (117)
Male-pattern baldness susceptibility locus at 20p11 (2008) (117)
Leukocyte telomere length is associated with cognitive performance in healthy women (2010) (117)
Assessment of Osteoarthritis Candidate Genes in a Meta-Analysis of Nine Genome-Wide Association Studies (2014) (117)
Heritability of central systolic pressure augmentation: a twin study. (2000) (116)
Nevus Size and Number Are Associated with Telomere Length and Represent Potential Markers of a Decreased Senescence In vivo (2007) (115)
The natural history of radiographic knee osteoarthritis: a fourteen-year population-based cohort study. (2012) (115)
The potential and limitations of meta-analysis. (1991) (114)
Novel genetic variants associated with lumbar disc degeneration in northern Europeans: a meta-analysis of 4600 subjects (2012) (114)
Safety and efficacy of the cathepsin K inhibitor ONO‐5334 in postmenopausal osteoporosis: The OCEAN study (2011) (114)
Geographical structure and differential natural selection among North European populations. (2009) (114)
Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness (2017) (113)
Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes (2013) (113)
Targeted metabolomics profiles are strongly correlated with nutritional patterns in women (2012) (112)
The Concordance and Heritability of Type 2 Diabetes in 34,166 Twin Pairs From International Twin Registers: The Discordant Twin (DISCOTWIN) Consortium (2015) (112)
The protective effect of the oral contraceptive pill on rheumatoid arthritis: an overview of the analytic epidemiological studies using meta-analysis. (1990) (112)
Inference and quantification of peptidoforms in large sample cohorts by SWATH-MS (2017) (112)
Deficiency of Prebiotic Fiber and Insufficient Signaling Through Gut Metabolite-Sensing Receptors Leads to Cardiovascular Disease (2020) (111)
Effective measurement of knee alignment using AP knee radiographs. (2009) (111)
Epigenetic associations of type 2 diabetes and BMI in an Arab population (2016) (111)
Markers of bone metabolism in postmenopausal women with rheumatoid arthritis. Effects of corticosteroids and hormone replacement therapy. (1995) (111)
Effects of strontium ranelate on spinal osteoarthritis progression (2007) (111)
Genetic contribution to renal function and electrolyte balance: a twin study. (2002) (111)
Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation (2015) (110)
The Genetic Architecture of Gene Expression in Peripheral Blood. (2017) (110)
Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits (2017) (110)
Trends in admissions for hip fracture in England and Wales, 1968-85. (1990) (110)
Arrhythmic Gut Microbiome Signatures Predict Risk of Type 2 Diabetes. (2020) (109)
Multisite Quantitative Ultrasound: Precision, Age- and Menopause-Related Changes, Fracture Discrimination, and T-score Equivalence with Dual-Energy X-ray Absorptiometry (2001) (109)
Mutation analysis of coding sequences for type I procollagen in individuals with low bone density (1994) (108)
Gut-Microbiota-Metabolite Axis in Early Renal Function Decline (2015) (108)
A cotwin control study of the relationship between hip osteoarthritis and bone mineral density. (2000) (108)
The St. Thomas' UK Adult Twin Registry. (2002) (107)
A Survey of UK Public Interest in Internet-Based Personal Genome Testing (2010) (107)
Returns to Education: Evidence from UK Twins (2002) (106)
Kellgren & Lawrence grade 1 osteophytes in the knee--doubtful or definite? (2003) (106)
Activation markers of coagulation and fibrinolysis in twins: heritability of the prethrombotic state (2002) (106)
Normal variations in personality are associated with coital orgasmic infrequency in heterosexual women: a population-based study. (2005) (106)
Novel Loci Associated with Usual Sleep Duration: The CHARGE Consortium Genome-Wide Association Study (2014) (104)
The genetic influence on radiographic osteoarthritis is site specific at the hand, hip and knee (2008) (104)
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution (2011) (104)
Telomere length in circulating leukocytes is associated with lung function and disease (2013) (103)
Heritability of the Second to Fourth Digit Ratio (2d:4d): A Twin Study (2006) (103)
Integration of ‘omics’ data in aging research: from biomarkers to systems biology (2015) (103)
Allelic variation at the interleukin-1 receptor antagonist gene is associated with early postmenopausal bone loss at the spine. (1998) (102)
Omics technologies and the study of human ageing (2013) (102)
Current smoking and COVID-19 risk: results from a population symptom app in over 2.4 million people (2021) (102)
Association of polymorphism at the type I collagen (COL1A1) locus with reduced bone mineral density, increased fracture risk, and increased collagen turnover. (1999) (102)
The classification and assessment of osteoarthritis. (1995) (101)
GDF5 single-nucleotide polymorphism rs143383 is associated with lumbar disc degeneration in Northern European women (2011) (101)
Germline genetic contributions to risk for esophageal adenocarcinoma, Barrett's esophagus, and gastroesophageal reflux. (2013) (100)
Safety of Hormone Replacement Therapy (HRT) in Systemic Lupus Erythematosus (SLE) (1994) (100)
Same genetic components underlie different measures of sweet taste preference. (2007) (100)
HLA alleles associated with risk of ankylosing spondylitis and rheumatoid arthritis influence the gut microbiome (2019) (100)
Patterns of joint involvement in osteoarthritis of the hand: the Chingford Study. (1995) (99)
A genome-wide association study of early menopause and the combined impact of identified variants (2013) (99)
Epidemiology of rheumatoid arthritis: update. (1990) (99)
An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins (2014) (99)
Measurement of structural progression in osteoarthritis of the hip: the Barcelona consensus group. (2004) (99)
Inference of the genetic architecture underlying BMI and height with the use of 20,240 sibling pairs. (2013) (98)
52 Genetic Loci Influencing Myocardial Mass. (2016) (98)
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine (2015) (98)
Body odor similarity in noncohabiting twins. (2005) (98)
Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus (2015) (98)
COVID-19 vaccine waning and effectiveness and side-effects of boosters: a prospective community study from the ZOE COVID Study (2022) (98)
Clinical signs of early osteoarthritis: reproducibility and relation to x ray changes in 541 women in the general population. (1991) (97)
Independent genetic factors determine the amount and distribution of fat in women after the menopause. (1997) (97)
Innate and adaptive immune traits are differentially affected by genetic and environmental factors (2017) (96)
Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium. (2010) (96)
Circulating Proteomic Signatures of Chronological Age (2014) (96)
Strontium Ranelate Reduces the Risk of Vertebral Fractures in Patients With Osteopenia (2006) (95)
Differences in genetic and environmental variation in adult BMI by sex, age, time period, and region: an individual-based pooled analysis of 40 twin cohorts. (2017) (95)
The influence of sensation seeking in the heritability of entrepreneurship (2008) (93)
Polymorphisms of the Vitamin D Receptor, Infant Growth, and Adult Bone Mass (1997) (93)
Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. (2012) (93)
Homocysteine levels and leukocyte telomere length. (2008) (92)
Heritability of serum TSH, free T4 and free T3 concentrations: a study of a large UK twin cohort (2008) (92)
TwinsUK: The UK Adult Twin Registry Update (2019) (92)
The relationship of joint hypermobility, bone mineral density, and osteoarthritis in the general population: the Chingford Study. (2003) (92)
Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health (2018) (91)
Obligatory and facilitative allelic variation in the DNA methylome within common disease-associated loci (2018) (91)
Determinants of pressure pain threshold in adult twins: evidence that shared environmental influences predominate (1997) (91)
A randomized trial of testosterone therapy in males with rheumatoid arthritis. (1996) (91)
Definition and epidemiology of osteoarthritis of the hand: a review. (2000) (91)
Racial and ethnic differences in COVID-19 vaccine hesitancy and uptake (2021) (91)
Low free testosterone levels in rheumatoid arthritis. (1988) (91)
A Randomized Controlled Trial of Vitamin D Supplementation on Preventing Postmenopausal Bone Loss and Modifying Bone Metabolism Using Identical Twin Pairs (2000) (91)
Adiponectin gene ADIPOQ SNP associations with serum adiponectin in two female populations and effects of SNPs on promoter activity (2008) (90)
Six Novel Susceptibility Loci for Early-Onset Androgenetic Alopecia and Their Unexpected Association with Common Diseases (2012) (90)
Self-Reported Symptoms of COVID-19, Including Symptoms Most Predictive of SARS-CoV-2 Infection, Are Heritable (2020) (90)
Whole-genome sequence-based analysis of thyroid function (2015) (89)
Glycosylation of Immunoglobulin G: Role of Genetic and Epigenetic Influences (2013) (89)
Transcript expression-aware annotation improves rare variant interpretation (2020) (89)
Association of the DVWA and GDF5 polymorphisms with osteoarthritis in UK populations (2008) (89)
Eight blood pressure loci identified by genome-wide association study of 34,433 people of European ancestry (2009) (88)
Radiographic Progression of Lumbar Spine Disc Degeneration Is Influenced by Variation at Inflammatory Genes: A Candidate SNP Association Study in the Chingford Cohort (2005) (88)
Metabolomic Identification of a Novel Pathway of Blood Pressure Regulation Involving Hexadecanedioate (2015) (88)
A General Factor of Personality: Evidence from the HEXACO Model and a Measure of Trait Emotional Intelligence (2009) (87)
Epigenetic Patterns in Blood Associated With Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results From Genome-Wide Association Studies (2017) (87)
Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior. (2016) (87)
The Genetic Architecture of Gene Expression in Peripheral Blood. (2017) (87)
Habitual flavonoid intakes are positively associated with bone mineral density in women (2012) (86)
Defining osteoarthritis of the hand for epidemiological studies: the Chingford Study. (1994) (86)
Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium. (2014) (86)
Hypermethylation in the ZBTB20 gene is associated with major depressive disorder (2014) (86)
Genetic influence on the progression of radiographic knee osteoarthritis: a longitudinal twin study. (2007) (86)
Evaluating drug targets through human loss-of-function genetic variation (2019) (86)
Eight Common Genetic Variants Associated with Serum DHEAS Levels Suggest a Key Role in Ageing Mechanisms (2011) (86)
Immunoglobulin G glycosylation and clinical outcome in rheumatoid arthritis during pregnancy. (2000) (85)
The Presence of Methylation Quantitative Trait Loci Indicates a Direct Genetic Influence on the Level of DNA Methylation in Adipose Tissue (2013) (85)
Meta‐analysis of genome‐wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women (2013) (84)
Population whole-genome bisulfite sequencing across two tissues highlights the environment as the principal source of human methylome variation (2015) (84)
The HBS1L-MYB intergenic region on chromosome 6q23.3 influences erythrocyte, platelet, and monocyte counts in humans. (2007) (84)
Genetic associations between frozen shoulder and tennis elbow: a female twin study. (2003) (84)
Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoarthritis. (2010) (84)
Obesity is Associated with Genetic Variants That Alter Dopamine Availability (2006) (84)
Heritability of macular pigment: a twin study. (2005) (84)
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations (2021) (83)
Quantitative trait loci for CD4:CD8 lymphocyte ratio are associated with risk of type 1 diabetes and HIV-1 immune control. (2010) (83)
Identification of Common Genetic Variants Influencing Spontaneous Dizygotic Twinning and Female Fertility. (2016) (83)
Relationship between dry eye symptoms and pain sensitivity. (2013) (82)
Moderate alcohol consumption, estrogen replacement therapy, and physical activity are associated with increased insulin sensitivity: is abdominal adiposity the mediator? (2003) (82)
UBE2L3 Polymorphism Amplifies NF-κB Activation and Promotes Plasma Cell Development, Linking Linear Ubiquitination to Multiple Autoimmune Diseases (2015) (82)
Pain reporting at different body sites is explained by a single underlying genetic factor (2010) (82)
Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade (2020) (82)
Diet quality and risk and severity of COVID-19: a prospective cohort study (2021) (80)
The rs1143679 (R77H) lupus associated variant of ITGAM (CD11b) impairs complement receptor 3 mediated functions in human monocytes (2012) (80)
Reduced telomere length in rheumatoid arthritis is independent of disease activity and duration (2006) (80)
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals (2022) (80)
A higher alkaline dietary load is associated with greater indexes of skeletal muscle mass in women (2013) (80)
Quantifying additional COVID-19 symptoms will save lives (2020) (79)
Painful knee but not hand osteoarthritis is an independent predictor of mortality over 23 years follow-up of a population-based cohort of middle-aged women (2015) (79)
Use of dietary indices to control for diet in human gut microbiota studies (2018) (79)
Causal Effect of Plasminogen Activator Inhibitor Type 1 on Coronary Heart Disease (2017) (78)
Genetic influences on female infidelity and number of sexual partners in humans: a linkage and association study of the role of the vasopressin receptor gene (AVPR1A). (2004) (78)
The effect of moderate alcohol consumption on bone mineral density: a study of female twins (2004) (78)
Family History of Appendicular Fracture and Risk of Osteoporosis: A Population-Based Study (1999) (78)
Association of social distancing and face mask use with risk of COVID-19 (2021) (78)
Causal Effect of Plasminogen Activator Inhibitor Type 1 on Coronary Heart Disease (2017) (78)
Vitamin-D-receptor-gene polymorphism and bone loss (1995) (78)
Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals (2019) (78)
Alcohol-induced metabolomic differences in humans (2013) (77)
Genome-wide association study with 1000 genomes imputation identifies signals for nine sex hormone-related phenotypes (2015) (77)
Pigmentation and Vitamin D Metabolism in Caucasians: Low Vitamin D Serum Levels in Fair Skin Types in the UK (2009) (77)
Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways (2017) (77)
Predicting causal variants affecting expression by using whole-genome sequencing and RNA-seq from multiple human tissues (2016) (77)
Self-reported COVID-19 vaccine hesitancy and uptake among participants from different racial and ethnic groups in the United States and United Kingdom (2022) (77)
Meta‐analysis of Genome‐Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology (2015) (76)
The influence of gender on the short and long‐term effects of growth hormone replacement on bone metabolism and bone mineral density in hypopituitary adults: a 5‐year study (2001) (76)
Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis (2016) (76)
How serious is knee osteoarthritis? (1992) (76)
A genome-wide association study identifies a novel locus on chromosome 18q12.2 influencing white cell telomere length (2009) (76)
No Correlation Between Childhood Maltreatment and Telomere Length (2010) (75)
Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium (2012) (75)
A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration. (2016) (75)
Characterizing Blood Metabolomics Profiles Associated with Self-Reported Food Intakes in Female Twins (2016) (75)
Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process (2014) (75)
Large scale meta-analysis of urinary C-terminal telopeptide, serum cartilage oligomeric protein and matrix metalloprotease degraded type II collagen and their role in prevalence, incidence and progression of osteoarthritis. (2014) (75)
Cross-cohort gut microbiome associations with immune checkpoint inhibitor response in advanced melanoma (2022) (75)
Quantitative trait locus on chromosome 8q influences the switch from fetal to adult hemoglobin. (2004) (74)
Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length (2020) (74)
Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability (2018) (74)
The role of bone metabolism in osteoarthritis (2003) (74)
Genetics of fibrin clot structure: a twin study. (2004) (73)
Association between a variation in LRCH1 and knee osteoarthritis: a genome-wide single-nucleotide polymorphism association study using DNA pooling. (2006) (73)
Gender Differences in the Genetic Factors Responsible for Variation in Bone Density and Ultrasound (2002) (73)
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative (2018) (73)
Mitochondrial DNA heteroplasmy in diabetes and normal adults: role of acquired and inherited mutational patterns in twins. (2012) (73)
Do openness to experience and recognizing opportunities have the same genetic source (2010) (73)
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative (2018) (73)
Modest effects of dietary supplements during the COVID-19 pandemic: insights from 445 850 users of the COVID-19 Symptom Study app (2021) (73)
The Microbiome and Musculoskeletal Conditions of Aging: A Review of Evidence for Impact and Potential Therapeutics (2016) (73)
Relation between insulin-like growth factor-I concentrations, osteoarthritis, bone density, and fractures in the general population: the Chingford study. (1996) (73)
Central retinal thickness is positively correlated with macular pigment optical density. (2006) (72)
Genetic and environmental influences on psychological distress in the population: General Health Questionnaire analyses in UK twins (2003) (72)
Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci (2019) (72)
Arterial Stiffening Relates to Arterial Calcification But Not to Noncalcified Atheroma in Women (2011) (71)
The genetic epidemiology of osteoarthritis (2010) (71)
The contribution of genes to osteoarthritis. (2008) (71)
Identification and Replication of Three Novel Myopia Common Susceptibility Gene Loci on Chromosome 3q26 using Linkage and Linkage Disequilibrium Mapping (2008) (71)
Methodological problems in the epidemiological study of osteoarthritis. (1994) (71)
DNA methylation studies using twins: what are they telling us? (2012) (71)
Use of oestrogen replacement therapy in high risk groups in the United Kingdom. (1989) (71)
Telomeres and the natural lifespan limit in humans (2017) (70)
Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure (2018) (70)
Genetic Variation in Bone Mineral Density and Calcaneal Ultrasound: A Study of the Influence of Menopause Using Female Twins (2001) (70)
A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans (2014) (69)
A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans (2014) (69)
Genetic and microbiome influence on lipid metabolism and dyslipidemia. (2018) (69)
Novel Approach Identifies SNPs in SLC2A10 and KCNK9 with Evidence for Parent-of-Origin Effect on Body Mass Index (2014) (69)
Evidence that bone mineral density plays a role in degenerative disc disease: the UK Twin Spine Study (2010) (69)
The effect of LRRK2 loss-of-function variants in humans (2020) (69)
Estrogen and COVID-19 symptoms: Associations in women from the COVID Symptom Study (2020) (68)
Association between a variation in the phosphodiesterase 4D gene and bone mineral density (2005) (68)
Randomised, controlled trial of avocado–soybean unsaponifiable (Piascledine) effect on structure modification in hip osteoarthritis: the ERADIAS study (2013) (68)
The heritability of corneal hysteresis and ocular pulse amplitude: a twin study. (2008) (68)
Association of a nsSNP in ADAMTS14 to some osteoarthritis phenotypes. (2009) (68)
PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION (2018) (67)
Common Genetic Variation Near the Phospholamban Gene Is Associated with Cardiac Repolarisation: Meta-Analysis of Three Genome-Wide Association Studies (2009) (67)
Evidence of association and linkage disequilibrium between a novel polymorphism in the transforming growth factor beta 1 gene and hip bone mineral density: a study of female twins. (2001) (67)
Socioeconomic Status and the Gut Microbiome: A TwinsUK Cohort Study (2019) (67)
Coexpression Network Analysis in Abdominal and Gluteal Adipose Tissue Reveals Regulatory Genetic Loci for Metabolic Syndrome and Related Phenotypes (2012) (67)
Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation (2017) (67)
Assessment of mechanism of acquired skewed X inactivation by analysis of twins. (2001) (67)
Effect of ONO‐5334 on Bone Mineral Density and Biochemical Markers of Bone Turnover in Postmenopausal Osteoporosis: 2‐Year Results From the OCEAN Study (2014) (67)
The relationship between DXA-based and anthropometric measures of visceral fat and morbidity in women (2013) (67)
Food Preference Patterns in a UK Twin Cohort (2015) (66)
Assessment of bone in ehlers danlos syndrome (EDS) by ultrasound and densitometry (1998) (66)
Novel mutations in the small leucine‐rich repeat protein/proteoglycan (SLRP) genes in high myopia (2007) (66)
Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants (2015) (66)
The clinical relevance of genetic susceptibility to osteoarthritis. (2010) (66)
Genetic and Environmental Influences on Female Sexual Orientation, Childhood Gender Typicality and Adult Gender Identity (2011) (66)
Can the WHO definition of osteoporosis be applied to multi-site axial transmission quantitative ultrasound? (2004) (66)
Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris (2014) (66)
Urinary collagen crosslinks reflect the radiographic severity of knee osteoarthritis. (1992) (65)
Linkage to the FOXC2 region of chromosome 16 for varicose veins in otherwise healthy, unselected sibling pairs (2005) (65)
Glycosylation Profile of Immunoglobulin G Is Cross-Sectionally Associated With Cardiovascular Disease Risk Score and Subclinical Atherosclerosis in Two Independent Cohorts (2018) (65)
Reduction of leucocyte telomere length in radiographic hand osteoarthritis: a population-based study (2006) (65)
Dietary Magnesium Is Positively Associated With Skeletal Muscle Power and Indices of Muscle Mass and May Attenuate the Association Between Circulating C‐Reactive Protein and Muscle Mass in Women (2016) (65)
A saturated map of common genetic variants associated with human height (2022) (65)
Genome-wide association study identifies 48 common genetic variants associated with handedness (2019) (65)
Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02 (2019) (65)
Long term conservation of human metabolic phenotypes and link to heritability (2014) (65)
Progression of lumbar disc degeneration over a decade: a heritability study (2011) (64)
The additive effect of individual genes in predicting risk of knee osteoarthritis (2007) (64)
Age-dependent changes in mean and variance of gene expression across tissues in a twin cohort (2016) (64)
The DOT1L rs12982744 polymorphism is associated with osteoarthritis of the hip with genome-wide statistical significance in males (2013) (64)
Genetics of osteoarthritis. (1996) (64)
Choosing the best method for radiological assessment of patellofemoral osteoarthritis. (1996) (63)
Genetic Predictors of Fibrin D-Dimer Levels in Healthy Adults (2011) (63)
A Genome-Wide Association Study Identifies an Osteoarthritis Susceptibility Locus on Chromosome 7 q 22 (2010) (63)
Twins and the genetic architecture of osteoarthritis. (1999) (63)
Amino Acid Intakes Are Associated With Bone Mineral Density and Prevalence of Low Bone Mass in Women: Evidence From Discordant Monozygotic Twins (2015) (63)
Genetic Influences on Metabolite Levels: A Comparison across Metabolomic Platforms (2016) (63)
Somatic point mutations occurring early in development: a monozygotic twin study (2013) (63)
Neuropathic features of joint pain: a community-based study. (2013) (63)
Epidemiology and Genetic Epidemiology of the Liver Function Test Proteins (2009) (62)
Linkage and potential association of obesity-related phenotypes with two genes on chromosome 12q24 in a female dizygous twin cohort (2006) (62)
Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk Factors (2015) (62)
Choline-stabilized orthosilicic acid supplementation as an adjunct to Calcium/Vitamin D3 stimulates markers of bone formation in osteopenic females: a randomized, placebo-controlled trial (2008) (62)
Meta-analysis of epigenome-wide association studies of cognitive abilities (2018) (62)
Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density (2016) (61)
Radiographic osteoarthritis at three joint sites and FRZB, LRP5, and LRP6 polymorphisms in two population-based cohorts. (2008) (61)
Emotional intelligence and its association with orgasmic frequency in women. (2009) (61)
GENOME-WIDE ASSOCIATION ANALYSES BASED ON WHOLE-GENOME SEQUENCING IN SARDINIA PROVIDE INSIGHTS INTO REGULATION OF HEMOGLOBIN LEVELS (2015) (61)
A metagenome-wide association study of gut microbiota in asthma in UK adults (2018) (61)
Level of an advanced glycated end product is genetically determined: a study of normal twins. (2003) (61)
PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity (2018) (61)
Genetic variation at 16q24.2 is associated with small vessel stroke (2017) (61)
Comparison of four articular indices for use in clinical trials in rheumatoid arthritis: patient, order and observer variation. (1991) (60)
A role for PACE4 in osteoarthritis pain: evidence from human genetic association and null mutant phenotype (2012) (60)
The heritability of polymorphic light eruption. (2000) (60)
DCAF4, a novel gene associated with leucocyte telomere length (2015) (60)
Genetic influence on peripheral blood T lymphocyte levels (2000) (60)
Genetic polymorphisms of innate immunity-related inflammatory pathways and their association with factors related to type 2 diabetes (2011) (60)
Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases (2020) (60)
Genes Contributing to Pain Sensitivity in the Normal Population: An Exome Sequencing Study (2012) (60)
Corrigendum: Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes (2011) (60)
ABO antigen and secretor statuses are not associated with gut microbiota composition in 1,500 twins (2016) (60)
A genome-wide association study suggests that a locus within the ataxin 2 binding protein 1 gene is associated with hand osteoarthritis: the Treat-OA consortium (2009) (59)
Identification of PLCL1 Gene for Hip Bone Size Variation in Females in a Genome-Wide Association Study (2008) (59)
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape (2016) (59)
Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects (2022) (59)
Genetic Relationship between Schizophrenia and Nicotine Dependence (2016) (58)
Within-sibship GWAS improve estimates of direct genetic effects (2021) (58)
The genetic aetiology of cannabis use initiation: a meta‐analysis of genome‐wide association studies and a SNP‐based heritability estimation (2013) (58)
Associations between branched chain amino acid intake and biomarkers of adiposity and cardiometabolic health independent of genetic factors: A twin study☆ (2016) (58)
Return to Education: Evidence from UK Twins (2003) (58)
Statins as modulators of bone formation (2002) (58)
Imputation of Variants from the 1000 Genomes Project Modestly Improves Known Associations and Can Identify Low-frequency Variant - Phenotype Associations Undetected by HapMap Based Imputation (2013) (58)
Association of adiposity genetic variants with menarche timing in 92,105 women of European descent. (2013) (57)
Relation between Heberden’s nodes and distal interphalangeal joint osteophytes and their role as markers of generalised disease (1998) (57)
Genetic influences on motion sickness susceptibility in adult women: a classical twin study. (2006) (57)
Genome-Wide Association Analysis of Eating Disorder-Related Symptoms, Behaviors, and Personality Traits (2012) (57)
New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders (2019) (57)
Amino Acid Intakes Are Inversely Associated with Arterial Stiffness and Central Blood Pressure in Women12 (2015) (57)
Adjusted Sequence Kernel Association Test for Rare Variants Controlling for Cryptic and Family Relatedness (2013) (57)
The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits (2015) (57)
Endogenous sex steroid levels in women with generalised osteoarthritis (1991) (57)
Diet and bone mineral density study in postmenopausal women from the TwinsUK registry shows a negative association with a traditional English dietary pattern and a positive association with wine. (2011) (56)
Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand (2017) (56)
Prevalence of rheumatoid arthritis and rheumatoid factor in women: evidence for a secular decline. (1993) (56)
Untangling the relationship between diet and visceral fat mass through blood metabolomics and gut microbiome profiling (2017) (56)
Type 1 diabetes susceptibility alleles are associated with distinct alterations in the gut microbiota (2018) (56)
Cerebral small vessel disease genomics and its implications across the lifespan (2020) (56)
Radiographic criteria for epidemiologic studies of osteoarthritis. (1995) (56)
Use of thermographic criteria to identify Raynaud's phenomenon in a population setting. (2003) (55)
Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia (2013) (55)
Does More Schooling Improve Health Outcomes and Health Related Behaviors? Evidence from U.K. Twins. (2013) (54)
Genetics of the human face: Identification of large-effect single gene variants (2018) (54)
Free and serum testosterone levels in 276 males: A comparative study of rheumatoid arthritis, ankylosing spondylitis and healthy controls (1989) (54)
Recommendations for the registration of drugs used in the treatment of osteoarthritis: an update on biochemical markers. (2001) (54)
Heritability maps of human face morphology through large-scale automated three-dimensional phenotyping (2016) (54)
Bone mineral density of patients with chronic plaque psoriasis (2001) (54)
Genetic and Environmental Influences on Lipids, Lipoproteins, and Apolipoproteins: Effects of Menopause (2001) (54)
Frequency of osteoarthritis in hysterectomized women. (1991) (53)
Intrinsic and extrinsic risk factors for sagging eyelids. (2014) (53)
Does obesity predict knee pain over fourteen years in women, independently of radiographic changes? (2011) (53)
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (2020) (53)
Haplotypes of the low-density lipoprotein receptor-related protein 5 (LRP5) gene: are they a risk factor in osteoarthritis? (2005) (52)
CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits (2017) (52)
Genome-wide association and functional studies identify a role for IGFBP3 in hip osteoarthritis (2014) (52)
Association of birth weight with osteoporosis and osteoarthritis in adult twins. (2003) (52)
Prevalence of premature ovarian failure in monozygotic and dizygotic twins. (2007) (51)
What should we hope to achieve when treating rheumatoid arthritis? (1989) (51)
Estimates of the rate of infection and asymptomatic COVID-19 disease in a population sample from SE England (2020) (51)
A genome-wide linkage scan for age at menarche in three populations of European descent. (2008) (51)
Dietary fat and fatty acid profile are associated with indices of skeletal muscle mass in women aged 18-79 years. (2014) (50)
Mixing omics: combining genetics and metabolomics to study rheumatic diseases (2017) (50)
Depressed levels of dehydroepiandrosterone sulphate in postmenopausal women with rheumatoid arthritis but no relation with axial bone density. (1993) (50)
The SH2B Gene is Associated with Serum Leptin and Body Fat in Normal Female Twins (2007) (50)
Association between KLOTHO gene and hand osteoarthritis in a female Caucasian population. (2007) (50)
Progression of central pulse pressure over 1 decade of aging and its reversal by nitroglycerin a twin study. (2012) (50)
Functional characterization of calcium sensing receptor polymorphisms and absence of association with indices of calcium homeostasis and bone mineral density (2006) (49)
An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis (2019) (49)
Metabolomic study of carotid–femoral pulse-wave velocity in women (2015) (49)
Extent, Causes, and Consequences of Small RNA Expression Variation in Human Adipose Tissue (2012) (49)
Ensemble landmarking of 3D facial surface scans (2018) (49)
Effects of Environmental Factors on Severity and Mortality of COVID-19 (2020) (49)
Role of the Nav1.7 R1150W amino acid change in susceptibility to symptomatic knee osteoarthritis and multiple regional pain (2011) (49)
A common genetic factor underlies hypertension and other cardiovascular disorders (2004) (49)
A candidate gene study of F cell levels in sibling pairs using a joint linkage and association analysis. (1999) (49)
The relation between progressive osteoarthritis of the knee and long term progression of osteoarthritis of the hand, hip, and lumbar spine (2005) (48)
First all-in-one diagnostic tool for DNA intelligence: genome-wide inference of biogeographic ancestry, appearance, relatedness, and sex with the Identitas v1 Forensic Chip (2012) (48)
Evaluation of the genetic overlap between osteoarthritis with body mass index and height using genome-wide association scan data (2012) (48)
Osteoporosis in rheumatoid arthritis. A monozygotic co-twin control study. (1995) (48)
Genetic and Environmental Correlations Between Trait Emotional Intelligence and Humor Styles (2009) (48)
A multivariate twin study of female sexual dysfunction. (2012) (48)
The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: a mendelian randomisation study (2013) (48)
Protein tyrosine phosphatase-1B gene PTPN1: selection of tagging single nucleotide polymorphisms and association with body fat, insulin sensitivity, and the metabolic syndrome in a normal female population. (2005) (47)
Comparison of three methods of intraocular pressure measurement and their relation to central corneal thickness (2010) (47)
Increased rates of previous hysterectomy and gynaecological operations in women with osteoarthritis. (1988) (47)
Glycosylation Profile of IgG in Moderate Kidney Dysfunction. (2016) (47)
A locus on chromosome 1p36 is associated with thyrotropin and thyroid function as identified by genome-wide association study. (2010) (47)
Meta-analysis of genome-wide association studies identifies 8 novel loci involved in shape variation of human head hair (2017) (47)
Using epigenome-wide association scans of DNA methylation in age-related complex human traits. (2012) (47)
Prevalence of reported knee pain over twelve years in a community-based cohort. (2012) (47)
Novel genetic loci affecting facial shape variation in humans (2019) (46)
Does estrogen replacement therapy protect against rheumatoid arthritis? (1991) (46)
Effects of cyclical etidronate combined with calcitriol versus cyclical etidronate alone on spine and femoral neck bone mineral density in postmenopausal osteoporotic women (1998) (46)
Identification of Novel Loci Associated With Hip Shape: A Meta‐Analysis of Genomewide Association Studies (2018) (46)
Is poor pregnancy outcome a risk factor in rheumatoid arthritis? (1990) (46)
The use of the twin model to investigate the genetics and epigenetics of skin diseases with genomic, transcriptomic and methylation data (2012) (46)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2019) (45)
Red Wine Consumption Associated With Increased Gut Microbiota α-diversity in 3 Independent Cohorts. (2019) (45)
Serum metabolites reflecting gut microbiome alpha diversity predict type 2 diabetes (2020) (45)
Exploring the molecular basis of age-related disease comorbidities using a multi-omics graphical model (2016) (45)
The effect of SARS-CoV-2 variant B.1.1.7 on symptomatology, re-infection and transmissibility (2021) (45)
Managing clinically significant findings in research: the UK10K example (2014) (45)
The prebiotic effects of omega-3 fatty acid supplementation: A six-week randomised intervention trial (2020) (45)
Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use (2019) (45)
Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness (2017) (45)
Diagnostic value of cutaneous manifestation of SARS‐CoV‐2 infection* (2021) (45)
Osteophytes, Enthesophytes, and High Bone Mass: A Bone-Forming Triad With Potential Relevance in Osteoarthritis (2014) (45)
Variance Components Models for Physical Activity With Age as Modifier: A Comparative Twin Study in Seven Countries (2011) (44)
Detection of stable community structures within gut microbiota co-occurrence networks from different human populations (2018) (44)
Moderate alcohol consumption, dietary fat composition, and abdominal obesity in women: evidence for gene-environment interaction. (2003) (44)
Plasma protein biomarkers of Alzheimer's disease endophenotypes in asymptomatic older twins: early cognitive decline and regional brain volumes (2015) (44)
Cancer and Risk of COVID‐19 Through a General Community Survey (2020) (44)
Recent advances in the genetics of osteoporosis. (2006) (44)
The Use of Genome-Wide eQTL Associations in Lymphoblastoid Cell Lines to Identify Novel Genetic Pathways Involved in Complex Traits (2011) (44)
Bisphosphonates: Potential therapeutic agents for disease modification in osteoarthritis (2003) (44)
Heritability of QT Interval: How Much Is Explained by Genes for Resting Heart Rate? (2008) (44)
Circulating levels of the anti-oxidant indoleproprionic acid are associated with higher gut microbiome diversity (2019) (43)
The gut microbiome: what the oncologist ought to know (2021) (43)
Genome-wide search for nevus density shows linkage to two melanoma loci on chromosome 9 and identifies a new QTL on 5q31 in an adult twin cohort. (2006) (43)
Natural history and risk factors for bone loss in postmenopausal Caucasian women: a 15-year follow-up population-based study (2008) (43)
A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk (2017) (43)
Contribution of Heritability and Epigenetic Factors to Skeletal Muscle Mass Variation in United Kingdom Twins (2016) (43)
Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity (2017) (43)
The heritability of plasma homocysteine, and the influence of genetic variation in the homocysteine methylation pathway. (2007) (43)
Blue poo: impact of gut transit time on the gut microbiome using a novel marker (2021) (43)
A population study of the screening potential of assessment of trabecular pattern of the femoral neck (Singh index): the Chingford Study. (1995) (43)
DNA methylation changes at infertility genes in newborn twins conceived by in vitro fertilisation (2017) (42)
Osteoporosis in neurological disorders (2000) (42)
Epigenome‐wide Association of DNA Methylation in Whole Blood With Bone Mineral Density (2017) (42)
Plasma adiponectin concentrations are associated with body composition and plant-based dietary factors in female twins. (2009) (42)
An Investigation Into Physical Frailty as a Link Between the Gut Microbiome and Cognitive Health (2018) (42)
Prevalence of radiographic hip osteoarthritis is increased in high bone mass (2014) (42)
Perimenopausal risk factors and future health. (2011) (42)
Osteoarthritis in the Aged (1995) (42)
Genetic and environmental influences on self-reported G-spots in women: a twin study. (2010) (42)
A Genome‐Screen of a Large Twin Cohort Reveals Linkage for Quantitative Ultrasound of the Calcaneus to 2q33–37 and 4q12–21 (2003) (42)
GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium (2016) (42)
Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero (2018) (42)
Obesity reveals an association between blood pressure and the G-protein beta3-subunit gene: a study of female dizygotic twins. (2004) (41)
Assessment of gene‐by‐sex interaction effect on bone mineral density (2012) (41)
Genome-Wide Meta-Analysis of Cotinine Levels in Cigarette Smokers Identifies Locus at 4q13.2 (2016) (41)
Genome-Wide Association Study Identifies Variants in Casein Kinase II (CSNK2A2) to be Associated With Leukocyte Telomere Length in a Punjabi Sikh Diabetic Cohort (2014) (41)
Genetic and environmental determinants on bone loss in postmenopausal Caucasian women: a 14-year longitudinal twin study (2009) (41)
Prediction of high naevus count in a healthy U.K. population to estimate melanoma risk (2016) (41)
A twin study of body dysmorphic concerns (2011) (41)
Physical activity reduces genetic susceptibility to increased central systolic pressure augmentation: a study of female twins. (2003) (40)
The complexities of the diet-microbiome relationship: advances and perspectives (2021) (40)
The genetics and epidemiology of female sexual dysfunction: a review. (2009) (40)
Genome-Wide Scan for Blood Pressure Suggests Linkage to Chromosome 11, and Replication of Loci on 16, 17, and 22 (2004) (40)
The fat on the joint: osteoarthritis and obesity. (1990) (40)
Genetic factors and osteoporotic fractures in elderly people (2000) (40)
Is telomere length in peripheral blood lymphocytes correlated with cancer susceptibility or radiosensitivity? (2007) (40)
Metabolomic profiling to dissect the role of visceral fat in cardiometabolic health (2016) (39)
Reproducibility and sensitivity to change of various methods to measure joint space width in osteoarthritis of the hip: a double reading of three different radiographic views taken with a three-year interval (2005) (39)
Blood, urine and faecal metabolite profiles in the study of adult renal disease. (2016) (39)
A Common Variant in the Telomerase RNA Component Is Associated with Short Telomere Length (2010) (39)
Genome-Wide Association Shows that Pigmentation Genes Play a Role in Skin Aging. (2017) (39)
Vascular Disease Arterial Stiffening Relates to Arterial Calcification But Not to Noncalcified Atheroma in Women A Twin Study (2011) (39)
Genes Versus Environment: The relationship between dietary fat and total and central abdominal fat (1998) (39)
Expression of Phosphofructokinase in Skeletal Muscle Is Influenced by Genetic Variation and Associated With Insulin Sensitivity (2014) (39)
The Effects of 10 Weeks Military Training on Heel Ultrasound and Bone Turnover (1999) (39)
Multimodality Imaging of Subclinical Aortic Atherosclerosis: Relation of Aortic Stiffness to Calcification and Plaque in Female Twins (2013) (39)
Genome-Wide Association Study for Circulating Tissue Plasminogen Activator Levels and Functional Follow-Up Implicates Endothelial STXBP5 and STX2 (2014) (39)
Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution (2009) (39)
Association between DHEAS and Bone Loss in Postmenopausal Women: A 15-Year Longitudinal Population-Based Study (2011) (38)
Detecting SARS-CoV-2 at point of care: preliminary data comparing loop-mediated isothermal amplification (LAMP) to polymerase chain reaction (PCR) (2020) (38)
Serum Lipid Levels and Risk Of Hand Osteoarthritis: The Chingford Prospective Cohort Study (2017) (38)
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction (2019) (38)
Identification of a role for the ARHGEF3 gene in postmenopausal osteoporosis. (2008) (38)
Genomewide linkage scan of hand osteoarthritis in female twin pairs showing replication of quantitative trait loci on chromosomes 2 and 19 (2006) (38)
Serum creatinine and fat-free mass (lean body mass). (2000) (38)
Replication of psychometric properties of the FSFI and validation of a modified version (FSFI-LL) assessing lifelong sexual function in an unselected sample of females. (2010) (38)
A meta-analysis of interleukin-6 promoter polymorphisms on risk of hip and knee osteoarthritis. (2010) (38)
Inflammation-induced cartilage degradation in female rodents. Protective role of sex hormones. (1993) (38)
Dissecting the role of the gut microbiota and diet on visceral fat mass accumulation (2019) (38)
Publisher Correction: Building an international consortium for tracking coronavirus health status (2020) (37)
Association of the resolvin precursor 17-HDHA, but not D- or E- series resolvins, with heat pain sensitivity and osteoarthritis pain in humans (2017) (37)
HbA2 levels in normal adults are influenced by two distinct genetic mechanisms (2013) (37)
Paternal age and telomere length in twins: the germ stem cell selection paradigm (2015) (37)
Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6 (2018) (37)
Effects of age on genetic influence on bone loss over 17 years in women: The Healthy Ageing Twin Study (HATS) (2012) (37)
Can biochemical markers predict bone loss at the hip and spine?: A 4-year prospective study of 141 early postmenopausal women (2005) (37)
Metabolomic Pathways to Osteoporosis in Middle‐Aged Women: A Genome‐Metabolome‐Wide Mendelian Randomization Study (2018) (37)
Linkage of genes to total lean body mass in normal women. (2007) (37)
The progression of radiological hand osteoarthritis over ten years: a clinical follow-up study. (1994) (37)
Illness Characteristics of COVID-19 in Children Infected with the SARS-CoV-2 Delta Variant (2021) (37)
Defining the genetic control of human blood plasma N-glycome using genome-wide association study (2018) (37)
Circulating Levels of the Short-Chain Fatty Acid Acetate Mediate the Effect of the Gut Microbiome on Visceral Fat (2021) (37)
Anosmia, ageusia, and other COVID-19-like symptoms in association with a positive SARS-CoV-2 test, across six national digital surveillance platforms: an observational study (2021) (37)
Individuals with high bone mass have an increased prevalence of radiographic knee osteoarthritis (2015) (37)
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study (2016) (37)
Strontium ranelate reduces the vertebral fracture risk in women with postmenopausal osteoporosis. (2002) (36)
Dietary garlic and hip osteoarthritis: evidence of a protective effect and putative mechanism of action (2010) (36)
Role of the gut microbiome for cancer patients receiving immunotherapy: Dietary and treatment implications. (2020) (36)
Evaluating the Consent Preferences of UK Research Volunteers for Genetic and Clinical Studies (2015) (36)
Serum cartilage oligomeric matrix protein and development of radiographic and painful knee osteoarthritis. A community-based cohort of middle-aged women (2015) (36)
Validation of statistical shape modelling to predict hip osteoarthritis in females: data from two prospective cohort studies (Cohort Hip and Cohort Knee and Chingford). (2015) (36)
Detecting COVID-19 infection hotspots in England using large-scale self-reported data from a mobile application: a prospective, observational study (2020) (36)
An Investigation of Unique and Shared Gene Effects on Speed of Sound and Bone Density Using Axial Transmission Quantitative Ultrasound and DXA in Twins (2003) (35)
Keratan sulphate in rheumatoid arthritis, osteoarthritis, and inflammatory diseases. (1992) (35)
Detecting SARS-CoV-2 at point of care: Preliminary data comparing Loop-mediated isothermal amplification (LAMP) to PCR (2020) (35)
Early detection of COVID-19 in the UK using self-reported symptoms: a large-scale, prospective, epidemiological surveillance study (2021) (35)
Factors affecting pupil size after dilatation: the Twin Eye Study (2000) (35)
Generalised Anxiety Disorder – A Twin Study of Genetic Architecture, Genome-Wide Association and Differential Gene Expression (2015) (35)
The epidemiology of osteoarthritis of the hand. (1995) (35)
QT interval in twins (2000) (35)
AMP-kinase α2 subunit gene PRKAA2 variants are associated with total cholesterol, low-density lipoprotein-cholesterol and high-density lipoprotein-cholesterol in normal women (2006) (35)
The pleasure principle (2007) (34)
An obesogenic postnatal environment is more important than the fetal environment for the development of adult adiposity: a study of female twins. (2009) (34)
Common variants in genes encoding adiponectin (ADIPOQ) and its receptors (ADIPOR1/2), adiponectin concentrations, and diabetes incidence in the Diabetes Prevention Program (2012) (34)
The relationship between sex steroids and bone mineral content in women soon after the menopause (1991) (34)
Whole Exome Re-Sequencing Implicates CCDC38 and Cilia Structure and Function in Resistance to Smoking Related Airflow Obstruction (2014) (34)
Tobacco smoking and oestrogen replacement are associated with lower total and central fat in monozygotic twins (1998) (34)
IgG glycosylation and DNA methylation are interconnected with smoking. (2018) (34)
Detecting COVID-19 infection hotspots in England using large-scale self-reported data from a mobile application: a prospective, observational study (2020) (34)
Large Scale Replication Study of the Association between HLA Class II/BTNL2 Variants and Osteoarthritis of the Knee in European-Descent Populations (2011) (34)
A Genome-Wide Screen for Interactions Reveals a New Locus on 4p15 Modifying the Effect of Waist-to-Hip Ratio on Total Cholesterol (2011) (34)
Association between cartilage and bone biomarkers and incidence of radiographic knee osteoarthritis (RKOA) in UK females: a prospective study. (2013) (34)
Heritability of Adult Body Height: A Comparative Study of Twin Cohorts in Eight Countries (2003) (33)
Genetic loci linked to pituitary-thyroid axis set points: a genome-wide scan of a large twin cohort. (2008) (33)
Multisite Quantitative Ultrasound: Colles’ Fracture Discrimination in Postmenopausal Women (2002) (33)
Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994 (2016) (33)
Integrative DNA methylome analysis of pan-cancer biomarkers in cancer discordant monozygotic twin-pairs (2016) (33)
The Identification of Hereditary and Environmental Determinants of Frailty in a Cohort of UK Twins (2016) (33)
Low Back and Common Widespread Pain Share Common Genetic Determinants (2014) (33)
Circulating levels of antioxidant vitamins correlate with better lung function and reduced exposure to ambient pollution. (2015) (33)
Heritability of intraocular pressure: a classical twin study (2008) (33)
Circulating metabolic biomarkers of renal function in diabetic and non-diabetic populations (2018) (33)
An omics investigation into chronic widespread musculoskeletal pain reveals epiandrosterone sulfate as a potential biomarker (2015) (33)
Association of metabolic syndrome with knee and hand osteoarthritis: A community-based study of women. (2018) (32)
Common genetic determinants of vitamin D insufficiency (2011) (32)
Illness duration and symptom profile in a large cohort of symptomatic UK school-aged children tested for SARS-CoV-2 (2021) (32)
Race, ethnicity, community-level socioeconomic factors, and risk of COVID-19 in the United States and the United Kingdom (2021) (32)
Replication of Associations of Genetic Loci Outside the HLA Region With Susceptibility to Anti–Cyclic Citrullinated Peptide–Negative Rheumatoid Arthritis (2016) (32)
The first "classical" twin study? Analysis of refractive error using monozygotic and dizygotic twins published in 1922. (2005) (32)
The heritability of macular response to supplemental lutein and zeaxanthin: a classic twin study. (2012) (32)
Joint Linkage and Association of Six Single-Nucleotide Polymorphisms in the Factor XIII-A Subunit Gene Point to V34L As the Main Functional Locus (2006) (31)
Insights into the genetics of osteoporosis from recent genome-wide association studies (2011) (31)
Genome-wide meta-analysis of common variant differences between men and women (2012) (31)
No evidence of an association between mitochondrial DNA variants and osteoarthritis in 7393 cases and 5122 controls (2012) (31)
Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne (2018) (31)
Pregnancy and Rheumatoid Arthritis: An Overview (1992) (31)
Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis (2019) (31)
Protective effect of androgens against inflammation induced cartilage degradation in male rodents. (1993) (31)
Genomics and metabolomics of muscular mass in a community-based sample of UK females (2015) (31)
Higher dietary flavonoid intakes are associated with lower objectively measured body composition in women: evidence from discordant monozygotic twins12 (2017) (30)
Novel genetic associations with serum level metabolites identified by phenotype set enrichment analyses. (2014) (30)
The COronavirus Pandemic Epidemiology (COPE) Consortium: A Call to Action (2020) (30)
Polymorphisms in ALOX12, but not ALOX15, Are Significantly Associated With BMD in Postmenopausal Women (2007) (30)
The Role of Serum TGF-β Isoforms as Potential Markers of Osteoporosis (1999) (30)
Zygosity Differences in Height and Body Mass Index of Twins From Infancy to Old Age: A Study of the CODATwins Project (2015) (30)
Heritability of insulin sensitivity and lipid profile depend on BMI: evidence for gene–obesity interaction (2009) (30)
Variation at the ANP32A gene is associated with risk of hip osteoarthritis in women. (2009) (30)
Health-related quality of life in osteoporosis clinical trials. The Osteoporosis Quality of Life Study Group. (1993) (30)
Postprandial glycaemic dips predict appetite and energy intake in healthy individuals (2021) (30)
Genome-wide average DNA methylation is determined in utero (2018) (30)
Investigation of Association Between Hip Osteoarthritis Susceptibility Loci and Radiographic Proximal Femur Shape (2015) (30)
Heritable components of the human fecal microbiome are associated with visceral fat (2016) (30)
Discovery of novel heart rate-associated loci using the Exome Chip (2017) (29)
Metabolomics profiling reveals novel markers for leukocyte telomere length (2016) (29)
A heritability-based comparison of methods used to cluster 16S rRNA gene sequences into operational taxonomic units (2016) (29)
Re: Age of death of parents for patients with RA. (1990) (29)
Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes (2020) (29)
Salt-inducible kinase 3, SIK3, is a new gene associated with hearing (2014) (29)
Repeated measures of intraocular pressure result in higher heritability and greater power in genetic linkage studies. (2009) (29)
Epigenetic findings in periodontitis in UK twins: a cross-sectional study (2019) (29)
Common genetic factors among sexual orientation, gender nonconformity, and number of sex partners in female twins: implications for the evolution of homosexuality. (2015) (29)
Risk of symptomatic Covid-19 among frontline healthcare workers (2020) (29)
Time-dependent genetic effects on gene expression implicate aging processes. (2017) (29)
A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine (2020) (29)
Genetic and Dietary Factors Influencing the Progression of Nuclear Cataract (2016) (29)
A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15 q 25 (2010) (29)
CD36 Gene Promoter Polymorphisms Are Associated With Low Density Lipoprotein-Cholesterol in Normal Twins and After a Low-Calorie Diet in Obese Subjects (2008) (28)
Disentangling the genetics of lean mass. (2019) (28)
Relationship between genome and epigenome - challenges and requirements for future research (2014) (28)
The protective effect of the oral contraceptive pill on rheumatoid arthritis: an overview of the analytical epidemiological studies using meta-analysis. (1989) (28)
The effect of genome-wide association scan quality control on imputation outcome for common variants (2011) (28)
The interaction of genes and smoking on forced expiratory volume: a classic twin study. (2007) (28)
Epigenetic discrimination of identical twins from blood under the forensic scenario. (2017) (28)
Change in body mass index during middle age affects risk of total knee arthoplasty due to osteoarthritis: A 19-year prospective study of 1003 women (2012) (28)
Genome-Wide Association Study Identifies Two Novel Regions at 11p15.5-p13 and 1p31 with Major Impact on Acute-Phase Serum Amyloid A (2010) (28)
Gradient Boosting as a SNP Filter: an Evaluation Using Simulated and Hair Morphology Data (2013) (28)
Longitudinal evaluation of sexual function in a cohort of pre- and postmenopausal women. (2015) (27)
Understanding coronary artery disease using twin studies (2012) (27)
High intake of vegetables is linked to lower white blood cell profile and the effect is mediated by the gut microbiome (2021) (27)
What is the evidence that osteoarthritis is genetically determined? (1997) (27)
Methodologic issues in clinical trials for prevention or risk reduction in osteoarthritis. (2011) (27)
SARS-CoV-2 (COVID-19) infection in pregnant women: characterization of symptoms and syndromes predictive of disease and severity through real-time, remote participatory epidemiology. (2020) (27)
Genome-wide methylation analysis of a large population sample shows neurological pathways involvement in chronic widespread musculoskeletal pain (2017) (27)
Heritability of Strabismus: Genetic Influence Is Specific to Eso-Deviation and Independent of Refractive Error (2012) (27)
A first update on mapping the human genetic architecture of COVID-19 (2022) (27)
A Genome-Wide Association Study of Monozygotic Twin-Pairs Suggests a Locus Related to Variability of Serum High-Density Lipoprotein Cholesterol (2012) (27)
Common polymorphisms in SOCS3 are not associated with body weight, insulin sensitivity or lipid profile in normal female twins (2006) (27)
Interaction Between Two Quantitative Trait Loci Affects Fetal Haemoglobin Expression (2005) (27)
Key predictors of attending hospital with COVID19: An association study from the COVID Symptom Tracker App in 2,618,948 individuals (2020) (27)
European Consensus Development Conference on menopause (1996) (27)
Novel regional age-associated DNA methylation changes within human common disease-associated loci (2016) (27)
Evaluation of HapMap data in six populations of European descent (2008) (27)
Genetic and Environmental Contributions to Humor Styles: A Replication Study (2008) (27)
Deep molecular phenotypes link complex disorders and physiological insult to CpG methylation (2018) (26)
Acetaminophen (Paracetamol) Use Modifies the Sulfation of Sex Hormones (2018) (26)
Metabolites of milk intake: a metabolomic approach in UK twins with findings replicated in two European cohorts (2016) (26)
Genetic and environmental risk factors for sexual distress and its association with female sexual dysfunction (2011) (26)
IgA1 Glycosylation Is Heritable in Healthy Twins. (2017) (26)
Genetic Influences on Cognitive Function Using the Cambridge Neuropsychological Test Automated Battery (2006) (26)
The heritability of optic disc parameters: a classic twin study. (2008) (25)
Vertebral anti-fracture efficacy of strontium ranelate according to pre-treatment bone turnover (2009) (25)
Meta‐Analysis of Genomewide Association Studies Reveals Genetic Variants for Hip Bone Geometry (2019) (25)
Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine (2016) (25)
Osteoarthritis in the aged. Epidemiological issues and optimal management. (1995) (25)
The Genetic and Environmental Structure of the Covariation Among the Symptoms of Insomnia, Fatigue, and Depression in Adult Females (2012) (25)
Genome-wide association study meta-analysis for quantitative ultrasound parameters of bone identifies five novel loci for broadband ultrasound attenuation (2017) (25)
Conducting metagenomic studies in microbiology and clinical research (2018) (25)
Global Genetic Architecture of an Erythroid Quantitative Trait Locus, HMIP-2 (2014) (25)
Sequence data and association statistics from 12,940 type 2 diabetes cases and controls (2017) (25)
Association of FTO gene variants with body composition in UK twins (2012) (25)
Global variability of the human IgG glycome (2019) (24)
Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study (2017) (24)
ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals (2018) (24)
Androgen status of females with RA. (1987) (24)
Kicking Back Cognitive Ageing: Leg Power Predicts Cognitive Ageing after Ten Years in Older Female Twins (2015) (24)
Author Correction: GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability (2019) (24)
Heritability of Raynaud's phenomenon and vascular responsiveness to cold: a study of adult female twins. (2007) (24)
Genome-wide association study in almost 195,000 individuals identifies 50 previously unidentified genetic loci for eye color (2021) (24)
Multicenter dizygotic twin cohort study confirms two linkage susceptibility loci for body mass index at 3q29 and 7q36 and identifies three further potential novel loci (2009) (24)
Genetic influences in gastro-oesophageal reflux disease: a twin study (2003) (24)
Significant differences in UK and US female bone density reference ranges (2010) (24)
Association of interleukin-6 gene polymorphisms with hand osteoarthritis and hand osteoporosis. (2014) (24)
Pain in knee osteoarthritis is associated with variation in the neurokinin 1/substance P receptor (TACR1) gene (2017) (24)
Heritability of DNA-damage-induced apoptosis and its relationship with age in lymphocytes from female twins (2006) (24)
Assessment of osteopenia from spine radiographs using two different methods: the Chingford Study. (1996) (24)
Proopiomelanocortin gene variants are associated with serum leptin and body fat in a normal female population (2005) (23)
Arterial stiffening is a heritable trait associated with arterial dilation but not wall thickening: a longitudinal study in the twins UK cohort (2018) (23)
Heritability analyses show visit-to-visit blood pressure variability reflects different pathological phenotypes in younger and older adults: evidence from UK twins (2013) (23)
The age-dependency of genetic and environmental influences on serum cytokine levels: a twin study. (2012) (23)
Decreasing initial telomere length in humans intergenerationally understates age-associated telomere shortening (2015) (23)
Metabolomic signatures of low birthweight: Pathways to insulin resistance and oxidative stress (2018) (23)
The Urinary Tract Microbiome in Older Women Exhibits Host Genetic and Environmental Influences. (2020) (23)
No clear genetic influences on the association between dyslexia and anxiety in a population-based sample of female twins. (2009) (23)
The inheritance of peripapillary atrophy. (2007) (23)
Association of adiponectin and leptin with relative telomere length in seven independent cohorts including 11,448 participants (2014) (23)
The etiological relationship between anxiety sensitivity, sexual distress, and female sexual dysfunction is partly genetically moderated. (2012) (23)
Genetic determinism in the relationship between human CD4 + and CD8 + T lymphocyte populations? (2001) (23)
Nonadditive Effects of Genes in Human Metabolomics (2015) (23)
Meta-analysis of genome-wide studies identifies MEF2C SNPs associated with bone mineral density at forearm (2013) (23)
Severe rheumatoid arthritis prohibits the pregnancy-induced decrease in α3-fucosylation of α1-acid glycoprotein (1998) (23)
Cross-trait analyses with migraine reveal widespread pleiotropy and suggest a vascular component to migraine headache (2020) (23)
An unsupervised learning approach to identify novel signatures of health and disease from multimodal data (2020) (23)
Further genetic evidence suggesting a role for the RhoGTPase-RhoGEF pathway in osteoporosis. (2009) (23)
A GWAS in Latin Americans identifies novel face shape loci, implicating VPS13B and a Denisovan introgressed region in facial variation (2021) (23)
A Prediction Model to Prioritize Individuals for a SARS-CoV-2 Test Built from National Symptom Surveys (2020) (23)
A Twin Study of Mitochondrial DNA Polymorphisms Shows that Heteroplasmy at Multiple Sites Is Associated with mtDNA Variant 16093 but Not with Zygosity (2011) (23)
Hearing Ability with Age in Northern European Women: A New Web-Based Approach to Genetic Studies (2012) (23)
Extending and improving metagenomic taxonomic profiling with uncharacterized species with MetaPhlAn 4 (2022) (22)
Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease (2021) (22)
Predicting the Risk of Fracture at Any Site in the Skeleton: Are All Bone Mineral Density Measurement Sites Equally Effective? (2005) (22)
Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals. (2019) (22)
An Automatic 3D Facial Landmarking Algorithm Using 2D Gabor Wavelets (2016) (22)
Height and Bone Mineral Density Are Associated with Naevus Count Supporting the Importance of Growth in Melanoma Susceptibility (2015) (22)
A systematic evaluation of 151 candidate genes for their association with osteoporosis and osteoporotic fracture in a meta-analysis of genome-wide association data (2009) (22)
Metabolomic Profiling of Long‐Term Weight Change: Role of Oxidative Stress and Urate Levels in Weight Gain (2017) (22)
The relation between insulin resistance and hemostasis: pleiotropic genes and common environment. (2003) (22)
Narrow-sense heritability estimation of complex traits using identity-by-descent information (2017) (22)
Low-frequency variation in TP53 has large effects on head circumference and intracranial volume (2018) (22)
Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses (2016) (22)
Variations in genome-wide gene expression in identical twins – a study of primary osteoblast-like culture from female twins discordant for osteoporosis (2004) (22)
SMAD3 Is Associated with the Total Burden of Radiographic Osteoarthritis: The Chingford Study (2014) (22)
Adiposity-Dependent Regulatory Effects on Multi-tissue Transcriptomes (2016) (21)
Use of a risk factor and dietary calcium questionnaire in predicting bone density and subsequent bone loss at the menopause. (1992) (21)
Cognitive Change in Older Women Using a Computerised Battery: A Longitudinal Quantitative Genetic Twin Study (2013) (21)
Ascorbic acid metabolites are involved in intraocular pressure control in the general population (2018) (21)
A Behavioral Genetic Study of Relationships Between Humor Styles And The Six HEXACO Personality Factors (2010) (21)
Strontium ranelate reduces the risk of non vertebral fractures in women with postmenopausal osteoporosis (2003) (21)
Codiversification of gut microbiota with humans (2021) (21)
Correction to: Type 1 diabetes susceptibility alleles are associated with distinct alterations in the gut microbiota (2018) (21)
Homozygous deletion of the UGT2B17 gene is not associated with osteoporosis risk in elderly Caucasian women (2011) (21)
Genetic architecture of circulating lipid levels (2011) (21)
Meal-induced inflammation: postprandial insights from the Personalised REsponses to DIetary Composition Trial (PREDICT) study in 1000 participants (2021) (21)
Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model (2011) (21)
Differences between race and sex in measures of hip morphology: a population-based comparative study. (2016) (21)
SHP-2 and PI3-kinase genes PTPN11 and PIK3R1 may influence serum apoB and LDL cholesterol levels in normal women. (2007) (21)
The Effects of Strontium Ranelate on the Risk of Vertebral Fracture in Women With Postmenopausal Osteoporosis (2004) (21)
Optimal symptom combinations to aid COVID-19 case identification: Analysis from a community-based, prospective, observational cohort (2021) (21)
Food: a new form of personalised (gut microbiome) medicine for chronic diseases? (2016) (21)
Extended haplotypes and linkage disequilibrium in the IL 1 R 1 – IL 1 A – IL 1 B – IL 1 RN gene cluster : association with knee osteoarthritis (2004) (20)
Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (Nature Genetics (2010) 42 (105-116)) (2010) (20)
Effects of statins on the immunoglobulin G glycome. (2017) (20)
Common Sequence Variation in FLNB Regulates Bone Structure in Women in the General Population and FLNB mRNA Expression in Osteoblasts In Vitro (2009) (20)
Phosphatidylinositol 3-kinase p85α regulatory subunit gene PIK3R1 haplotype is associated with body fat and serum leptin in a female twin population (2006) (20)
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2017) (20)
Longitudinal study of variation in body mass index in middle-aged UK females (2012) (20)
SNP heritability and effects of genetic variants for neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio (2017) (20)
Parathyroid Hormone(1–84) Treatment of Postmenopausal Women with Low Bone Mass Receiving Hormone Replacement Therapy (2008) (20)
Lack of heritability of circulating leptin concentration in humans after adjustment for body size and adiposity using a physiological approach (2001) (20)
Higher Nevus Count Exhibits a Distinct DNA Methylation Signature in Healthy Human Skin: Implications for Melanoma (2017) (20)
The relationship between retinal arteriolar and venular calibers is genetically mediated, and each is associated with risk of cardiovascular disease. (2011) (19)
Relation of birth weight, body mass index, and change in size from birth to adulthood to insulin resistance in a female twin cohort. (2008) (19)
Linkage and Association for Bone Mineral Density and Heel Ultrasound Measurements with a Simple Tandem Repeat Polymorphism near the Osteocalcin Gene in Female Dizygotic Twins (2002) (19)
The person-to-person transmission landscape of the gut and oral microbiomes (2023) (19)
Identification of Quantitative Trait Loci for Fibrin Clot Phenotypes: The EuroCLOT Study (2009) (19)
Author Correction: Attributes and predictors of long COVID (2021) (19)
Epigenetics and methylation in the rheumatic diseases. (2014) (19)
Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology. (2019) (19)
A Variant in MCF 2 L Is Associated with Osteoarthritis (19)
DNA Methylation Changes in the IGF1R Gene in Birth Weight Discordant Adult Monozygotic Twins (2015) (19)
STEROID OSTEOPOROSIS : A PRAGMATIC APPROACH IS NEEDED WHILE PROSPECTIVE TRIALS ARE AWAITED (1993) (19)
A short-term run-in study can significantly contribute to increasing the quality of long-term osteoporosis trials. The strontium ranelate phase 3 program (2002) (19)
Genetic and Environmental Contributions to Perceived Intensity and Pleasantness of Androstenone Odor: An International Twin Study (2008) (19)
Contribution of the COMT Val158Met variant to symptomatic knee osteoarthritis (2013) (19)
A Genome-Wide Association Study of Female Sexual Dysfunction (2012) (19)
Happy families: a twin study of humour (2000) (18)
Migraine and Antiphospholipid Antibodies: No Association Found in Migraine-Discordant Monozygotic Twins (2008) (18)
Elevated plasma fractalkine levels are associated with higher levels of IL-6, Apo-B, LDL-C and insulin, but not with body composition in a large female twin sample. (2013) (18)
Spiking of the tibial tubercles--a radiological feature of osteoarthritis? (1996) (18)
Novel genes for QTc interval. How much heritability is explained, and how much is left to find? (2010) (18)
Size at birth, adult intestinal calcium absorption and 1,25(OH)(2) vitamin D. (2002) (18)
Genetic aetiology of blood pressure relates to aortic stiffness with bi-directional causality: evidence from heritability, blood pressure polymorphisms, and Mendelian randomization. (2020) (18)
Variants Close to NTRK2 Gene Are Associated With Birth Weight in Female Twins (2014) (18)
The relationship between same-sex sexual experience, sexual distress, and female sexual dysfunction. (2012) (18)
Abdominal Aortic Calcification Detection Using Dual-Energy X-Ray Absorptiometry: Validation Study in Healthy Women Compared to Computed Tomography (2013) (18)
Large-scale Meta-analysis of Genome-wide Association (GWA) Scans for Osteoporosis Traits: the GEFOS Consortium (2008) (18)
Interrogating causal pathways linking genetic variants, small molecule metabolites, and circulating lipids (2014) (18)
Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval (2018) (18)
Yoghurt consumption is associated with changes in the composition of the human gut microbiome and metabolome (2022) (17)
Epigenome-Wide DNA Methylation in Hearing Ability: New Mechanisms for an Old Problem (2014) (17)
Femoral neck trabecular patterns predict osteoporotic fractures. (2002) (17)
Effect of UBE2L3 genotype on regulation of the linear ubiquitin chain assembly complex in systemic lupus erythematosus (2015) (17)
Affective responses to sweet products and sweet solution in British and Finnish adults (2017) (17)
Real-time tracking of self-reported symptoms to predict potential COVID-19 (2020) (17)
Successful pregnancy in a neurologically impaired woman with Wilson's disease. (1997) (17)
Can Your Microbiome Tell You What to Eat? (2015) (17)
Accessible data curation and analytics for international-scale citizen science datasets (2020) (17)
Genome-Wide Association Study for Circulating Tissue Plasminogen Activator Levels and Functional Follow-Up Implicates Endothelial STXBP 5 and STX 2 (2014) (17)
Robust, reproducible clinical patterns in hospitalised patients with COVID-19 (2020) (17)
Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (2018) (17)
The role of serum TGF-beta isoforms as potential markers of osteoporosis. (1999) (17)
Geometric measurements of the proximal femur in UK women: Secular increase between the late 1950s and early 1990s (2005) (17)
Extensive weight loss reduces glycan age by altering IgG N-glycosylation (2021) (17)
Phenotypic and Genetic Relations Between the HEXACO Dimensions and Trait Emotional Intelligence (2010) (17)
Genome-Wide Association Studies Identify Multiple Genetic Loci Influencing Eyebrow Color Variation in Europeans. (2019) (16)
A Method for Determining Skeletal Lengths from DXA Images (2007) (16)
Influence of oral contraception on the occurrence of rheumatoid arthritis in female sibs. (1990) (16)
Erratum to: signatures of early frailty in the gut microbiota (2016) (16)
Novel association suggests multiple independent QTLs within chromosome 5q21–33 region control variation in total humans IgE levels (2003) (16)
The use of radiographs in assessing the severity of knee osteoarthritis. (1991) (16)
Anxiety and depression symptoms after COVID-19 infection: results from the COVID Symptom Study app (2021) (16)
The heritable determinants of cartilage oligomeric matrix protein. (2006) (16)
A Comparison of Heritability Estimates by Classical Twin Modeling and Based on Genome-Wide Genetic Relatedness for Cardiac Conduction Traits (2017) (16)
Investigation of linkage on chromosome 2q and hand and knee osteoarthritis. (2002) (16)
Epidemiology of the rheumatic diseases (1987) (16)
A polygenic and phenotypic risk prediction for Polycystic Ovary Syndrome evaluated by Phenome-wide association studies. (2020) (16)
The CODATwins Project: The Current Status and Recent Findings of COllaborative Project of Development of Anthropometrical Measures in Twins (2019) (16)
Genome-wide association study of circulating interleukin 6 levels identifies novel loci (2021) (16)
Current tobacco smoking and risk from COVID-19: results from a population symptom app in over 2.4 million people (2020) (16)
Carpal tunnel syndrome and hormone replacement therapy. (1992) (16)
Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance (2014) (16)
Identification and Functional Characterization of G 6 PC 2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G 6 PC 2-ABCB 11 Locus (2015) (16)
Dietary Interventions Reduce Traditional and Novel Cardiovascular Risk Markers by Altering the Gut Microbiome and Their Metabolites (2021) (16)
Association of Common JAK2 Variants With Body Fat, Insulin Sensitivity and Lipid Profile (2008) (16)
Genome-wide methylation analysis identifies ELOVL5 as an epigenetic biomarker for the risk of type 2 diabetes mellitus (2018) (16)
Causal Relationship between Obesity and Vitamin D Status (2016) (16)
When is a replication not a replication? Or how to spot a good genetic association study. (2006) (16)
Traduction française des recommandations de l’Osteoarthritis Research Society International (OARSI) sur la prise en charge de la gonarthrose et de la coxarthrose (2009) (15)
The genetics of osteoporosis. (2007) (15)
Investigating the Epigenetic Discrimination of Identical Twins Using Buccal Swabs, Saliva, and Cigarette Butts in the Forensic Setting (2018) (15)
Predicting Personal Metabolic Responses to Food Using Multi-omics Machine Learning in over 1000 Twins and Singletons from the UK and US: The PREDICT I Study (OR31-01-19). (2019) (15)
Identical twins carry a persistent epigenetic signature of early genome programming (2021) (15)
Symptoms and syndromes associated with SARS-CoV-2 infection and severity in pregnant women from two community cohorts (2021) (15)
Identical twins carry a persistent epigenetic signature of early genome programming (2021) (15)
Genome‐wide association study of hoarding traits (2011) (15)
Anosmia and other SARS-CoV-2 positive test-associated symptoms, across three national, digital surveillance platforms as the COVID-19 pandemic and response unfolded: an observation study (2020) (15)
The Rate of Nonallelic Homologous Recombination in Males Is Highly Variable, Correlated between Monozygotic Twins and Independent of Age (2014) (15)
Genome-wide association analysis of lifetime cannabis use (N=184,765) identifies new risk loci, genetic overlap with mental health, and a causal influence of schizophrenia on cannabis use (2018) (15)
COVID-19 due to the B.1.617.2 (Delta) variant compared to B.1.1.7 (Alpha) variant of SARS-CoV-2: a prospective observational cohort study (2021) (15)
Severe rheumatoid arthritis prohibits the pregnancy-induced decrease in alpha3-fucosylation of alpha1-acid glycoprotein. (1998) (15)
Copy number variation of the APC gene is associated with regulation of bone mineral density☆ (2012) (15)
Lumbar disc disease shows linkage to chromosome 19 overlapping with a QTL for hand OA (2007) (15)
Integrated multiomics approach identifies calcium and integrin-binding protein-2 as a novel gene for pulse wave velocity (2015) (15)
Genetic Influences on Osteoarthritis (1996) (15)
Geo-social gradients in predicted COVID-19 prevalence and severity in Great Britain: results from 2,266,235 users of the COVID-19 Symptoms Tracker app (2020) (15)
Intrauterine, Environmental, and Genetic Influences in the Relationship Between Birth Weight and Lipids in a Female Twin Cohort (2006) (15)
Two candidate genes for low platelet count identified in an Asian Indian kindred by genome-wide linkage analysis: glycoprotein IX and thrombopoietin (2006) (15)
Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity (2020) (14)
Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies (2023) (14)
The role of heredity in determining central retinal thickness (2007) (14)
Dysregulated Antibody, Natural Killer Cell and Immune Mediator Profiles in Autoimmune Thyroid Diseases (2020) (14)
Personalised REsponses to DIetary Composition Trial (PREDICT): an intervention study to determine inter-individual differences in postprandial response to foods (2020) (14)
Decreased Immunoglobulin G Core Fucosylation, A Player in Antibody-dependent Cell-mediated Cytotoxicity, is Associated with Autoimmune Thyroid Diseases* (2020) (14)
An analysis of which anti-osteoporosis therapeutic regimen would improve compliance in a population of elderly adults (2007) (14)
TUB is a candidate gene for late-onset obesity in women (2007) (14)
Efficacy and safety of the cathepsin K inhibitor, ONO-5334, and alendronate on post-menopausal osteopenia or osteoporosis: 2-year results from the ocean study (2011) (14)
A Discordant Monozygotic Twin Approach to Testing Environmental Influences on Sexual Dysfunction in Women (2013) (14)
Effect on bone turnover and BMD of low dose oral silicon as an adjunct to calcium/vitamin D3 in a randomized, placebo-controlled trial (2005) (14)
Using epigenomic studies in monozygotic twins to improve our understanding of cancer. (2014) (14)
Relation of arterial stiffness to left ventricular structure and function in healthy women (2018) (14)
Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention (2022) (14)
The genetic contribution to hip joint morphometry and relationship to hip cartilage thickness. (2001) (14)
Genome Wide Association Analysis of a Founder Population Identified TAF3 as a Gene for MCHC in Humans (2013) (14)
Genetic analysis of over one million people identifies 535 novel loci for blood pressure (2017) (14)
Knowledge barriers in the symptomatic-COVID-19 testing programme in the UK: an observational study (2021) (13)
Hemodynamic Mechanism of the Age-Related Increase in Pulse Pressure in Women (2019) (13)
Sequencing of SCN5A Identifies Rare and Common Variants Associated With Cardiac Conduction: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium (2014) (13)
The incidence and characteristics of accelerated knee osteoarthritis among women: the Chingford cohort (2020) (13)
Where did I leave my keys? A twin study of self-reported memory ratings using the multifactorial memory questionnaire. (2005) (13)
Does the negative association between rheumatoid arthritis and schizophrenia provide clues to the aetiology of rheumatoid arthritis? (1987) (13)
Body site‐specific genetic effects influence naevus count distribution in women (2020) (13)
Autosomal genetic control of human gene expression does not differ across the sexes (2016) (13)
Assessment of age-related changes in heritability and IGF-1 gene effect on circulating IGF-1 levels (2014) (13)
Are slow-acting antirheumatic drugs being given earlier in rheumatoid arthritis? (1988) (13)
Consumption of Stilbenes and Flavonoids is Linked to Reduced Risk of Obesity Independently of Fiber Intake (2020) (13)
Increased levels of urinary collagen crosslinks in females with rheumatoid arthritis (1993) (13)
Reproducibility and sensitivity to change of various methods of joint space width (JSW) measurements in osteoarthritis of the hip (OAH). A double reading of three different radiographic views taken within a 3-year time-interval. (2005) (13)
Asymmetrical nodular osteoarthritis in a patient with a hemiparesis. (1995) (13)
Genetic and environmental influences on stability and change in baseline levels of C-reactive protein: A longitudinal twin study. (2017) (13)
Twin studies advance the understanding of gene–environment interplay in human nutrigenomics (2014) (13)
Ethnic differences in F cell levels in Jamaica: a potential tool for identifying new genetic loci controlling fetal haemoglobin (2009) (12)
Association of Cross-Sectional and Longitudinal Change in Arterial Stiffness With Gene Expression in the Twins UK Cohort (2016) (12)
Structure modifying effects of Strontium Ranelate in knee osteoarthritis (2012) (12)
Genetics of human gut microbiome composition (2020) (12)
Genome-wide scan identifies novel genetic loci regulating salivary metabolite levels (2019) (12)
Identification of PLCL 1 Gene for Hip Bone Size Variation in Females in a Genome-Wide Association Study (2008) (12)
Age Differences in Genetic and Environmental Variations in Stress-Coping During Adulthood: A Study of Female Twins (2012) (12)
Quantitative Linkage Analysis for Pancreatic B-cell Function and Insulin Resistance in a Large Twin Cohort (2008) (12)
A study of pathophysiological factors associated with gastro‐esophageal reflux disease in twins discordant for gastro‐esophageal reflux symptoms (2013) (12)
Identification of QTLs for serum lipid levels in a female sib-pair cohort: a novel application to improve the power of two-locus linkage analysis. (2005) (12)
App-based COVID-19 syndromic surveillance and prediction of hospital admissions in COVID Symptom Study Sweden (2022) (12)
Gut microbiome diversity and composition is associated with hypertension in women (2021) (12)
Interaction between allelic variations in vitamin D receptor and retinoid X receptor genes on metabolic traits (2014) (12)
Impact of COVID-19 on health behaviours and body weight: A prospective observational study in a cohort of 1.1 million UK and US individuals (2021) (12)
Epigenetic Signatures at AQP3 and SOCS3 Engage in Low-Grade Inflammation across Different Tissues (2016) (12)
Genomic Insights into Adaptations of Trimethylamine-Utilizing Methanogens to Diverse Habitats, Including the Human Gut (2021) (12)
Association of social distancing and masking with risk of COVID-19 (2020) (11)
Genes and environment in refractive error (2001) (11)
A response to Videman et al., "challenging the cumulative injury model: positive effects of greater body mass on disc degeneration". (2010) (11)
Profiling post-COVID syndrome across different variants of SARS-CoV-2 (2022) (11)
A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids (2021) (11)
Do gene–environment interactions influence fasting plasma lipids? A study of twins (2004) (11)
Definitive Zygosity Scores in the Peas in the Pod Questionnaire is a Sensitive and Accurate Assessment of the Zygosity of Adult Twins (2018) (11)
Polymorphisms of the vitamin d receptor gene do not predict quantitative ultrasound of the calcaneus or hip axis length (2005) (11)
A susceptibility locus for myopia in the normal population is linked to the PAX 6 gene region : a genome-wide scan of dizygotic twins . Running title : PAX 6 and myopia in the normal population (2004) (11)
Diagnostic value of skin manifestation of SARS-CoV-2 infection (2020) (11)
Genome-wide Scan for Prospective Memory Suggests Linkage to Chromosome 12q22 (2006) (11)
Twins: A cloning experience. (2006) (11)
A study of possible associations between single nucleotide polymorphisms in the estrogen receptor 2 gene and female sexual desire. (2015) (11)
Genetic correlations reveal the shared genetic architecture of transcription in human peripheral blood (2017) (11)
Associations between UK tap water and gut microbiota composition suggest the gut microbiome as a potential mediator of health differences linked to water quality. (2020) (11)
An Epidemiological Survey of Post-Coital Psychological Symptoms in a UK Population Sample of Female Twins (2011) (11)
OARSI ) recommendations for the management of knee and hip osteoarthritis (2009) (11)
PREGNANCY IN PATIENTS WITH PREEXISTING TRANSVERSE MYELITIS (1996) (10)
Pilot study to investigate the efficacy and safety of microcurrent therapy in the short term management of primary knee osteoarthritis (2006) (10)
A letter to the editor on the article by Burri et al. (2010) (10)
Beta 3-adrenergic receptor gene polymorphisms and determination of adiposity and fat distribution in normal female twins. (1997) (10)
Host genetic variation impacts microbiome composition across human body sites (2015) (10)
Common genetic variation in the Estrogen Receptor Beta (ESR2) gene and osteoarthritis: results of a meta-analysis (2010) (10)
Differential effects of hormone replacement therapy on bone mineral density and axial transmission ultrasound measurements in cortical bone (2003) (10)
Evidence for similarity in testosterone levels in haplotype identical brothers. (1988) (10)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (10)
Immune Trait Shifts in Association With Tobacco Smoking: A Study in Healthy Women (2021) (10)
Quantitative Trait Loci for Bone Lengths on Chromosome 5 Using Dual Energy X-Ray Absorptiometry Imaging in the Twins UK Cohort (2008) (10)
A comparison of radiographic anatomic axis knee alignment measurements and cross-sectional associations with knee osteoarthritis (2016) (10)
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche DTU Orbit (05/11/2017) (2014) (10)
KCND3 potassium channel gene variant confers susceptibility to electrocardiographic early repolarization pattern (2019) (10)
Analysis of antibody binding specificities in twin and SNP-genotyped cohorts reveals that antiviral antibody epitope selection is a heritable trait. (2022) (10)
Impacts of dietary exposure to pesticides on faecal microbiome metabolism in adult twins (2021) (10)
Session 1: Epidemiology and genetics of hand osteoarthritis (2000) (10)
Dietary Influence on Systolic and Diastolic Blood Pressure in the TwinsUK Cohort (2020) (10)
Estimating Returns to Education Using a New Sample of UK Twins (2000) (10)
Lower limbs composition and radiographic knee osteoarthritis (RKOA) in Chingford sample--a longitudinal study. (2013) (10)
Should healthy people take a vitamin D supplement in winter months? (2016) (10)
Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium (2012) (10)
Evaluation of PAX3 genetic variants and nevus number (2013) (9)
What happens to patients with rheumatoid arthritis? The long-term outcome of treatment (1988) (9)
Natural history of naevi: a two‐wave study (2020) (9)
Blood DNA methylation sites predict death risk in a longitudinal study of 12,300 individuals (2020) (9)
Common STAT3 Variants Are Not Associated With Obesity or Insulin Resistance in Female Twins (2007) (9)
Challenges and opportunities for better nutrition science—an essay by Tim Spector and Christopher Gardner (2020) (9)
Erratum: Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes (Nature Genetics (2011) 43 (561-564)) (2011) (9)
N-glycosylation of immunoglobulin G predicts incident hypertension (2021) (9)
Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation (2019) (9)
Conditional testing of multiple variants associated with bone mineral density in the FLNB gene region suggests that they represent a single association signal (2013) (9)
Influence of Current and Past Hormone Replacement Therapy on Bone Mineral Density: A Study of Discordant Postmenopausal Twins (1999) (9)
Risk factors for osteoarthritis : genetics 1 (2003) (9)
The Pharmacogenetic Footprint of ACE Inhibition: A Population-Based Metabolomics Study (2016) (9)
Lack of association between leukocyte telomere length and genetic variants in two ageing-related candidate genes (2007) (9)
Sex hormone measurements in rheumatoid arthritis. (1989) (9)
Anxiety and depression symptoms after COVID-19 infection: results from the COVID Symptom Study app (2021) (9)
Epidemiological Issues and Optimal Management (1995) (9)
Geo-social gradients in predicted COVID-19 prevalence in Great Britain: results from 1 960 242 users of the COVID-19 Symptoms Study app (2020) (8)
Pathway-Based Factor Analysis of Gene Expression Data Produces Highly Heritable Phenotypes That Associate with Age (2015) (8)
Twenty loci associated with bone mineral density identified by large-scale meta-analysis of genome-wide association datasets (2009) (8)
Oestrogens, joint disease, and cartilage. (1991) (8)
THE ASSOCIATION BETWEEN HIP MORPHOLOGY AND END-STAGE OSTEOARTHRITIS AT 12-YEAR FOLLOW UP (2012) (8)
Rare and common genetic determinants of metabolic individuality and their effects on human health (2022) (8)
Immunoglobulin G glycome composition in transition from premenopause to postmenopause (2021) (8)
First demonstration of the efficacy of an anti-osteoporotic treatment in very elderly osteoporotic women. (2004) (8)
Plasma N-glycome shows continuous deterioration as the diagnosis of insulin resistance approaches (2021) (8)
Epidemiological aspects of studying outcome in rheumatoid arthritis. (1988) (8)
Cutaneous Manifestations of SARS‐CoV‐2 infection during the Delta and Omicron waves in 348,691 UK users of the UK ZOE COVID Study App (2022) (8)
Dietary supplements during the COVID-19 pandemic: insights from 1.4M users of the COVID Symptom Study app - a longitudinal app-based community survey (2020) (8)
Diet and lifestyle behaviour disruption related to the pandemic was varied and bidirectional among US and UK adults participating in the ZOE COVID Study (2021) (8)
Genetics of osteoporosis from genome-wide association studies: advances and challenges (2012) (8)
Attitudes towards human reproductive cloning, assisted reproduction and gene selection: a survey of 4600 British twins. (2007) (8)
Plant-based nutrient intake is positively associated with fat free mass index (2012) (8)
Molecular pathways associated with blood pressure and hexadecanedioate levels (2017) (8)
Erratum to: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits : (Nature Genetics, (2018), 50, 10, (1412-1425), 10.1038/s41588-018-0205-x) (2018) (8)
Quantifying the degree of sharing of genetic and non-genetic causes of gene expression variability across four tissues (2016) (8)
Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass (2017) (8)
Fine-Mapping of the Human Blood Plasma N-Glycome onto Its Proteome (2019) (8)
Risedronate produces disease modification and symptomatic benefit in the treatment of knee osteoarthritis: results from the BRISK study (2003) (8)
A large-scale population-based analysis of common genetic variation in the thyroid hormone receptor alpha locus and bone. (2012) (8)
Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium (2019) (7)
Discovering patterns of pleiotropy in genome-wide association studies (2018) (7)
Antiviral Antibody Epitope Selection is a Heritable Trait (2021) (7)
Distinct clinical symptom patterns in patients hospitalised with COVID-19 in an analysis of 59,011 patients in the ISARIC-4C study (2022) (7)
Evidence for the increasing prevalance of osteoarthritis with ageing: does this pertain to the oldest old? (1997) (7)
Does education attenuate the genetic risk of obesity? Evidence from U.K. Twins (2018) (7)
ACE Inhibitors, ARBs and Other Anti-Hypertensive Drugs and Novel COVID-19: An Association Study from the COVID Symptom Tracker App in 2,215,386 Individuals (2020) (7)
Decreased Immunoglobulin G Core Fucosylation, A Player in Antibody-dependent Cell-mediated Cytotoxicity, is Associated with Autoimmune Thyroid Diseases. (2020) (7)
Faecal transplants (2015) (7)
Hereditary factors in basal cell carcinoma of the skin: a population-based cohort study in twins (1999) (7)
Sib-TDT analysis of human TGF-beta1 gene single nucleotide polymorphisms in female twins: evidence for linkage and association with blood pressure at the codon 263 polymorphism (2000) (7)
Impact of insufficient sleep on dysregulated blood glucose control under standardised meal conditions (2021) (7)
Modeling with Measured Genotypes: Effects of the Vitamin D Receptor Gene, Age, and Latent Genetic and Environmental Factors on Bone Mineral Density (2004) (7)
370 A GENOME-WIDE ASSOCIATION STUDY IDENTIFIES A LOCUS ON CHROMOSOME 7Q22 TO INFLUENCE SUSCEPTIBILITY FOR OSTEOARTHRITIS (2009) (6)
Differences in genetic and environmental variation in adult body mass index by sex , age , time period , and region : an individual-based pooled analysis of 40 twin cohorts (2017) (6)
559 EVALUATION OF THE STRUCTURE-MODIFYING EFFECT OF AVOCADO-SOYBEAN UNSAPONIFIABLES (ASU) IN HIP OSTEOARTHRITIS (OA): RESULTS OF THE ERADIAS STUDY A 3-YEAR PROSPECTIVE RANDOMIZED DOUBLE-BLIND PLACEBO CONTROLLED TRIAL (2010) (6)
A comparative study between corresponding structural geometric variables using 2 commonly implemented hip structural analysis algorithms applied to dual-energy X-ray absorptiometry images. (2009) (6)
A Bidirectional Mendelian Randomization Study to evaluate the causal role of reduced blood vitamin D levels with type 2 diabetes risk in South Asians and Europeans (2021) (6)
Genetic Influences on Female Infidelity and Number of Sexual Partners in Humans: A Linkage and Association Study of the Role of the Vasopressin Receptor Gene (AVPR1A) (2004) (6)
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences (2019) (6)
Oral contraceptives and rheumatoid arthritis. Bias in observational studies of cause-effect relationships. (1987) (6)
Metabolome Genome-Wide Association Study Identifies 74 Novel Genomic Regions Influencing Plasma Metabolites Levels (2022) (6)
Knowledge barriers in a national symptomatic-COVID-19 testing programme (2022) (6)
Strain-Level Analysis of Bifidobacterium spp. from Gut Microbiomes of Adults with Differing Lactase Persistence Genotypes (2020) (6)
Genetic discovery and translational decision support from exome sequencing of 20,791 type 2 diabetes cases and 24,440 controls from five ancestries (2018) (6)
Metabolomic profiling identifies novel associations with Electrolyte and Acid-Base Homeostatic patterns (2019) (6)
Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption (Proceedings of the National Academy Sciences of the United States of America (2011) 108, 17, (7119-7124)) (2011) (6)
MixFit: Methodology for Computing Ancestry-Related Genetic Scores at the Individual Level and Its Application to the Estonian and Finnish Population Studies (2017) (6)
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids (2021) (6)
Optimal symptom combinations to aid COVID-19 case identification: analysis from a community-based, prospective, observational cohort (2020) (6)
The narrow-sense and common single nucleotide polymorphism heritability of early repolarization. (2019) (6)
Decreased IgG core fucosylation, a player in antibody-dependent cell-mediated cytotoxicity, is associated with autoimmune thyroid diseases (2018) (6)
Disentangling post-vaccination symptoms from early COVID-19 (2021) (6)
Epigenome-Wide Association Study of Thyroid Function Traits Identifies Novel Associations of fT3 With KLF9 and DOT1L. (2021) (6)
The association between hip morpholgy and 19-year risk of osteoarthritis in the hip (2012) (6)
Positive Association Between Vitamin D Serum Levels and Naevus Counts. (2017) (6)
Association of Lumbar Spine Radiographic Changes With Severity of Back Pain–Related Disability Among Middle-aged, Community-Dwelling Women (2021) (6)
Interpreting the results of a segregation analysis of generalized radiographic osteoarthritis: comment on the article by Felson et al. (1999) (6)
A new 5-lipoxygenase inhibitor seems to be safe and effective for the treatment of osteoarthritis (2009) (5)
DEFINING OSTEOARTHRITIS OF THE HAND FOR EPIDEMIOLOGIC STUDIES (1993) (5)
An epidemiological approach to the study of outcome in rheumatoid arthritis. (1992) (5)
Where Did I Leave My Keys? A Twin Study of Self-Reported Memory Ratings Using the Multifactorial Memory Questionnaire (2005) (5)
Variation and Heritability in Hair Diameter and Curvature in an Australian Twin Sample (2016) (5)
Bivariate genetic modelling of the response to an oral glucose tolerance challenge: A gene × environment interaction approach (2009) (5)
A UK case-control study on the effect of parity and the oral contraceptive pill on the development of rheumatoid arthritis. (1989) (5)
Erratum: Global analysis of dna methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements ((Journal of Human Genetics (2013) 93 (876-890)) (2013) (5)
Multimodality Imaging of Subclinical Aortic AtherosclerosisNovelty and Significance (2013) (5)
Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders (2018) (5)
Racial and ethnic determinants of Covid-19 risk (2020) (5)
Differential DNA Methylation in Monozygotic Twins Discordant for Female Sexual Functioning. (2017) (5)
Health-related quality of life in osteoporosis clinical trials urinary calcium loss (2005) (5)
Measuring joint space in knee osteoarthritis: position or precision? (1995) (5)
The genetics of osteoarthritis. (1996) (5)
Genome Wide Association Study Identifies Two Novel Loci Associated with Female Stress and Urgency Urinary Incontinence. (2021) (5)
Genome Wide Association Metanalysis Of Skull Bone Mineral Density Identifies Loci Relevant For Osteoporosis And Craniosynostosis (2021) (5)
Acne and Telomere Length: A New Spectrum between Senescence and Apoptosis Pathways. (2017) (5)
Large Inter-individual Variation in Postprandial Lipemia Following a Mixed Meal in over 1000 Twins and Singletons from the UK and US: The PREDICT I Study (OR19-06-19). (2019) (5)
Amino Acid Intake Is Inversely Associated with Arterial Stiffness and Central Blood Pressure in Women (2015) (5)
Genomewide linkage scan of hand osteoarthritis in female twin pairs showing replication of QTLs on chromosome 2 and 19. (2006) (5)
Oestrogens, Bones Systemic Lupus Erythematosus (1993) (5)
Extensive weight loss can reduce immune age by altering IgG N-glycosylation (2020) (5)
Genome Wide Association Study in 8,997 Women Identifies Novel Genetic Variants At Five Genomic Loci Associated with Stress and Urgency Urinary Incontinence (2014) (5)
Patients who have had fractures of the distal forearm do not lose bone as expected (1996) (5)
Body mass index mediates the effect of the DASH diet on hypertension: Common metabolites underlying the association. (2021) (5)
Safety and efficacy of PTH(1-84) at 18 and 24 months in women with postmenopausal osteoporosis receiving hormone therapy: Results from the POWER study (2005) (5)
Serum BCAAs to histidine ratio: a novel metabolomic biomarker of knee osteoarthritis. (2010) (5)
The use of estrogen replacement as an adjunct therapy in rheumatoid arthritis (1994) (5)
A probabilistic model of biological ageing of the lungs for analysing the effects of smoking, asthma and COPD (2013) (5)
Predicting Incident Radiographic Knee Osteoarthritis in Middle‐Aged Women Within Four Years: The Importance of Knee‐Level Prognostic Factors (2019) (5)
Association analyses of 47,500 individuals identifies six fracture loci and 82 BMD loci clustering in biological pathways that regulate osteoblast and osteoclast activity (2011) (5)
Correction: Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria (2019) (4)
Genome-wide association study identifies 48 common genetic variants associated with handedness (2020) (4)
Pulmonary Function and Blood DNA Methylation: A Multiancestry Epigenome-Wide Association Meta-analysis (2022) (4)
Post-vaccination SARS-CoV-2 infection: risk factors and illness profile in a prospective, observational community-based case-control study (2021) (4)
Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls (2018) (4)
A Letter to the Editor on the Article by Farnam et al. (2010) (4)
The genomic loci of specific human tRNA genes exhibit ageing-related DNA hypermethylation (2019) (4)
Circulating inflammatory proteins associate with response to immune checkpoint inhibition therapy in patients with advanced melanoma (2022) (4)
Exploring Genetic and Environmental Influences on Miscarriage Rates: A Twin Study (2010) (4)
Arrhythmic gut microbiome signatures for risk profiling of Type-2 Diabetes (2019) (4)
Menopause is associated with postprandial metabolism, metabolic health and lifestyle: The ZOE PREDICT study (2022) (4)
Network-based metabolite ratios for an improved functional characterization of genome-wide association study results (2016) (4)
Differential associations between a priori diet quality scores and markers of cardiovascular health in women: cross-sectional analyses from TwinsUK (2020) (4)
Specific body mass index trajectories were related to musculoskeletal pain and mortality: 19‐year follow‐up cohort (2021) (4)
Epidemiology of Osteoporosis (1998) (4)
Bone structural effects of variation in the TNFRSF1B gene encoding the tumor necrosis factor receptor 2 (2008) (4)
Parametric model‐based statistics for possible genotyping errors and sample stratification in sibling‐pair SNP data (2009) (4)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (4)
Parental mortality and rheumatoid arthritis. (1988) (4)
Facet joint osteoarthritis and bone density measurements (2006) (4)
Epidemiology and genetics of hand osteoarthritis. (2000) (4)
Aging Trajectories in Different Body Systems Share Common Environmental Etiology: The Healthy Aging Twin Study (HATS) (2016) (4)
Hippurate as a metabolomic marker of gut microbiome diversity: Modulation by diet and relationship to metabolic syndrome (2017) (4)
normal females associated with total-, ldl-and hdl-cholesterol in Amp-kinase alpha 2 subunit gene prkaa 2 variants are (2006) (4)
The epidemiology of rheumatic diseases (1991) (4)
356 COMMON VARIANTS IN SKELETAL DYSPLASIA GENES ARE ASSOCIATED WITH OSTEOARTHRITIS (2011) (4)
Quantitative genetics of circulating Dickkopf-related protein 1 (DKK1) in community-based sample of UK twins (2016) (4)
Supplementary Material 3 (2015) (3)
Contribution of putative genetic factors and candidate gene variants to inter-individual variation of circulating fractalkine (CX3CL1) levels in a large UK twins' sample. (2013) (3)
The genetic predisposition to osteoarthritis (2009) (3)
Macular Pigment Heritability: A Twin Study (2005) (3)
Variants associated with HHIP expression have sex-differential effects on lung function. (2020) (3)
The mental health burden of racial and ethnic minorities during the COVID-19 pandemic (2022) (3)
Gut microbiota associations with common diseases and prescription medications in a population-based cohort (2018) (3)
Accelerated aortic imaging using small field of view imaging and electrocardiogram‐triggered quadruple inversion recovery magnetization preparation (2011) (3)
Concordance of B‐ and T‐cell responses to SARS‐CoV‐2 infection, irrespective of symptoms suggestive of COVID‐19 (2022) (3)
Whole-genome sequencing identifies common-to-rare variants associated with human blood metabolites (2017) (3)
Genome-wide association study using family-based cohorts identifies the WLS and CCDC 170 / ESR 1 loci as associated with bone mineral density (2016) (3)
Could food act as personalized medicine for chronic disease? (2017) (3)
Steroid osteoporosis. (1993) (3)
An overview of the TwinsUK cohort’s anxiety and depression assessment, using the self-reported Hospital Anxiety and Depression Scale (2019) (3)
Correction for Schumann et al., Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption (2011) (3)
Dietary retinol intake and bone mineral density: A study of postmenopausal monozygous twins (1997) (3)
The urinary tract microbiome in older women exhibits host genetics and environmental influences (2019) (3)
Alendronate: a new bisphosphonate for the treatment of osteoporosis. (1996) (3)
Genetic prediction of male pattern baldness based on large independent datasets (2022) (3)
Uses of twins in studying the genetics of complex traits (2000) (3)
[Radiological evaluation of osteoarthritis]. (1996) (3)
Joint Hypermobility in the general population is common and strongly genetically determined: Results of a study of female twins from a national sample. (2003) (3)
Genetic influence on early age-related macular degeneration: a population-based twin study. (2001) (3)
An automatic 3 D facial landmarking algorithm using 2 D Gabor Wavelets (2015) (3)
Strontium ranelate: a new treatment for osteoporosis. (2004) (3)
Oral Abstracts 7: RA ClinicalO37. Long-Term Outcomes of Early RA Patients Initiated with Adalimumab Plus Methotrexate Compared with Methotrexate Alone Following a Targeted Treatment Approach (2013) (3)
Author Correction: The mutational constraint spectrum quantified from variation in 141,456 humans (2021) (3)
Estimating the risks of faecal transplants. (2016) (3)
genetic epidemiology of hip and knee (2011) (3)
Twin Studies and Epigenetics (2015) (3)
Do current regimes of hormone replacement therapy protect against subsequent fractures? (1992) (3)
Effect of Postprandial Glucose Dips on Hunger and Energy Intake in 1102 Subjects in US and UK: The PREDICT 1 Study (2020) (3)
Adiponectin and bone mineral density in postmenopausal women (2007) (3)
Profound perturbation of the human metabolome by obesity (2018) (3)
Genomic insights into adaptations of TMA-utilizing methanogens to diverse habitats including the human gut (2020) (3)
Supplementary Material 7 (2014) (3)
Supplementary Material 5 (2014) (3)
Supplementary Material 6 (2014) (3)
Fine mapping provides further evidence of linkage for bone mineral density to 3p21. (2004) (3)
Maternal genome-wide association study identifies a fasting glucose variant associated with offspring birth weight (2015) (3)
Validity of continuous glucose monitoring for categorizing glycemic responses to diet: implications for use in personalized nutrition (2022) (3)
Large meta-analysis of genome-wide association studies identifies five loci for lean body mass (2017) (3)
Author Correction: Self-reported COVID-19 vaccine hesitancy and uptake among participants from different racial and ethnic groups in the United States and United Kingdom (2022) (3)
83 ANALYSIS OF CANDIDATE OSTEOARTHRITIS GENES IN A META-ANALYSIS OF 8 GENOME-WIDE ASSOCIATION STUDIES (2011) (3)
Imaging of pelvic fracture in a patient with psoriatic arthritis. (1999) (3)
Comment on the article by Hernandez-Avila et al. (1991) (3)
Research gaps and opportunities in precision nutrition: an NIH workshop report. (2022) (3)
Host genetic and environmental factors shape the human gut resistome (2020) (3)
Variation in the FLNB gene regulates bone density in two populations of Caucasian women (2007) (3)
Effects of body weight and fat mass on back pain - direct mechanical or indirect through inflammatory and metabolic parameters? (2021) (3)
Large-scale genome-wide screen of female twin pairs confirms presence of QTLs for BMD at 1p36 and 3p21 (2002) (2)
Intervertebral T-score differences in younger and older women. (2013) (2)
Correction to: Type 1 diabetes susceptibility alleles are associated with distinct alterations in the gut microbiota (2018) (2)
High heritability of central corneal thickness : the twins eye studies (2005) (2)
The cohort description of collaborative project of development of anthropometrical measures in twins (CODATwins) to study macro-environmental variation in genetic and environmental effects on anthropometric traits (2015) (2)
Dissecting the role of the gut microbiota and diet on visceral fat mass accumulation (2019) (2)
Comparison of Heterochromatic Flicker Photometry and Fundus Autofluorescence as Methods of Measuring Levels of Macular Pigment in vivo (2005) (2)
The gut microbiome, health and personalised nutrition (2022) (2)
Increased habitual flavonoid intake predicts attenuation of cognitive ageing in twins (2021) (2)
A Comparison of Symptom Prevalence, Severity and Duration in the SARS-CoV-2 Omicron Versus Delta Variants Among Vaccinated Individuals from the ZOE COVID Study (2022) (2)
Intrauterine programming effects on BP independent of parental influences: Evidence from 1309twin pairs (2000) (2)
Bacon rashers, statistics, and controversy (2019) (2)
Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity (2017) (2)
Comparison of serum FSH and Inhibin B levels between adult male dizygotic and monozygotic twins. (2006) (2)
Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease (2022) (2)
Genome-Wide Association Study Reveals Genetic Variants Associated with Bone Mineral Density, Osteoporosis and Osteoporotic Fractures (2008) (2)
Publisher Correction: Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability (2019) (2)
Publisher Correction: Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways (2019) (2)
Machine learning integration of multimodal data identifies key features of blood pressure regulation (2022) (2)
Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney (2017) (2)
Integrating Metagenomic Information into Personalized Nutrition Tools: The PREDICT I Study (P20-005-19). (2019) (2)
Are diet and physical activity risk factors for gastro-oesophageal reflux disease symptoms in discordant twins? (2005) (2)
Higher serum levels of cartilage oligomeric matrix protein (comp) are associated with self-reported knee pain (2014) (2)
Sibship size does not increase the risk of developing rheumatoid arthritis. (1992) (2)
PREVALENCE AND PREDICTORS OF KNEE PAIN WITH NEUROPATHIC FEATURES IN A COMMUNITY BASED COHORT (2012) (2)
University of Groningen Physical Activity Attenuates the Influence of FTO Variants on Obesity Risk (2011) (2)
The genetic epidemiology of strabismus: the twin eye study (2002) (2)
Genetic Factors Determine the Liability to Back Pain Reporting: Results of a Population Based MRI Study of Twins (2001) (2)
The relationship between osteoarthritis and osteoporosis (2004) (2)
Lowfree testosterone levels inrheumatoid arthritis (1988) (2)
GDF5 SNP rs143383 is associated with lumbar disc disease in northern European women. (2010) (2)
Early menopausal bone loss at the spine is associated with polymorphism at the interleukin 1 receptor antagonist locus (1997) (2)
Novel DNA methylation sites of glucose and insulin homeostasis: an integrative cross-omics analysis (2018) (2)
The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions (2023) (2)
DEFINING THE PRESENCE OF OSTEOARTHRITIS OF THE KNEE IN EPIDEMIOLOGIC STUDIES (1992) (2)
Microbiome Signatures of Nutrients, Foods and Dietary Patterns: Potential for Personalized Nutrition from The PREDICT 1 Study (2020) (2)
Vertebral and non-vertebral anti-fracture efficacy of strontium ranelate in very elderly women with osteoporosis (2005) (2)
Meta-analysis of the NaV1.7 R1150W amino acid change in symptomatic knee osteoarthritis and multiple regional pain (2011) (2)
Influence of acquired obesity on coronary vessel wall late gadolinium enhancement in discordant monozygote twins (2016) (2)
Widespread smell testing for COVID-19 has limited application – Authors' reply (2020) (2)
Genetic and Environmental Influences of Dietary Indices in a UK Female Twin Cohort (2020) (2)
bone mineral density: a study of female twins The effect of moderate alcohol consumption on (2005) (2)
European Congress on Osteoporosis & Osteoarthritis (IOF-ECCEO12) (2012) (2)
Predicting genome-wide DNA methylation using methylation marks, genomic position, and DNA regulatory elements (2015) (2)
Authors’ reply to Mawer and Wilcox and Mullish and Williams (2015) (2)
Are intra-articular injections of hylan more effective than injections of hyaluronic acid for knee osteoarthritis? (2008) (2)
Strain-level analysis of Bifidobacterium spp. from gut microbiomes of adults of differing lactase persistence genotypes (2020) (2)
Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility (2016) (2)
Causal metabolomic pathways to osteoporosis in elderly women (2013) (2)
Gene expression changes with age in skin, adipose tissue, blood and brain (2013) (2)
Tim Spector: Butter or margarine? Food religion challenged (2019) (2)
348 A GENOME WIDE ASSOCIATION STUDY ON JOINT SPACE WIDTH IDENTIFIES A NEW GENE INVOLVED IN CARTILAGE THICKNESS AND OSTEOARTHRITIS (2011) (1)
Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology. (2019) (1)
Discovery and Refinement Supplementary (2015) (1)
Unsupervised integration of multimodal dataset identifies novel signatures of health and disease (2018) (1)
Novel metabolomic biomarkers for osteoporosis and longitudinal bone loss (2012) (1)
Genome-wide association and large scale follow-up identifies 16 novel loci for lung function (2011) (1)
Research methods in epidemiology , V The potential and limitations of meta-analysis (1)
A genome-wide association study identifies a susceptibility 1 locus for refractive errors and myopia at 15 q 14 2 3 (2010) (1)
Transcriptome Sequencing Reveals Widespread Gene-Gene and Gene-Environment Interactions (2014) (1)
Genetic Influences in Self-Reported Symptoms of Obstructive Sleep Apnoea and Restless Legs: A Twin Study (2004) (1)
Genome-wide association study of offspring birth weight in 86,577 women highlights maternal genetic effects that are independent of fetal genetics (2017) (1)
Aspirin and NSAID use and the risk of COVID-19 (2021) (1)
Concurrent Oral 3 – Genetics and Epidemiology [OP16–OP23] OP16. Genetic Variation in the Dream Pain Modulation Pathway is Associated with the Extent of Musculoskeletal Pain (2010) (1)
KCND3 is a novel susceptibility locus for early repolarization (2019) (1)
App-based COVID-19 surveillance and prediction: The COVID Symptom Study Sweden (2021) (1)
Definition ofosteoarthritis ofthekneefor epidemiological studies (1993) (1)
Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity (2018) (1)
Optimizing patient adherence and persistence in strontium ranelate phase 3 program using a short term run-in study (2002) (1)
Genetics & Genomics and Epigenetics 370 A GENOME-WIDE ASSOCIATION STUDY IDENTIFIES A LOCUS ON CHROMOSOME 7 Q 22 TO INFLUENCE SUSCEPTIBILITY FOR OSTEOARTHRITIS (2009) (1)
Interaction between allelic variations in vitamin D receptor and retinoid X receptor genes on metabolic traits (2014) (1)
Role of ephrin genes in cortical cataract pathogenesis (2013) (1)
Publisher Correction: A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids (2021) (1)
and with osteoarthritis in UK populations Association of the DVWA and GDF 5 polymorphisms (2008) (1)
Strontium ranelate reduces the risk of vertebral fractures in osteoporotic postmenopausal women without prevalent vertebral fracture (2004) (1)
Autosomal genetic control of human gene expression does not differ across the sexes (2016) (1)
North European populations Geographical structure and differential natural selection among Material Supplemental (2009) (1)
Strontium ranelate decreases vertebral fracture risk whatever the level of pretreatment bone turnover markers (2007) (1)
IS WAIST CIRCUMFERENCE A BETTER PREDICTOR OF INCIDENT SYMPTOMATIC RADIOGRAPHIC KNEE OSTEOARTHRITIS, RADIOGRAPHIC KNEE OSTEOARTHRITIS AND KNEE PAIN THAN BODY MASS INDEX OVER 10 YEARS? (2016) (1)
Physical activity and sedentary behavior; mechanistic insights and role in disease prevention (2021) (1)
Supplementary Material 15 (2013) (1)
Use of dietary indices to control for diet in human gut microbiota studies (2018) (1)
GENETIC INFLUENCES ON ULTRASOUND OF THE CALCANEUS AND HIP AXIS LENGTH - A TWIN STUDY (1995) (1)
Accelerated biological aging in people with Down syndrome with full and segmental trisomy 21 begins in childhood as revealed by immunoglobulin G glycosylation (2021) (1)
A Common Single Nucleotide Polymorphism in the Chromosome 7q22.3 Region, Which Is Frequently Deleted in Myeloid Malignancies, Is Associated with Mean Platelet Volume and Platelet Function in Healthy Individuals (2008) (1)
Genetic contribution to knee radiographic osteoarthritis and knee alignment: A classical twin study (2006) (1)
MILD RADIOGRAPHIC FEATURES PREDICT STRUCTURAL PROGRESSION OF KNEE OSTEOARTHRITIS (2010) (1)
Cardiovascular Risk Factors Are Increased in People Reporting Chronic Pain Symptoms (2010) (1)
University of Groningen A Genome-Wide Screen for Interactions Reveals a New Locus on 4 p 15 Modifying the Effect of Waist-to-Hip Ratio on Total Cholesterol (2011) (1)
Genes and environment in the expression of naevi in adults: sunbed use is associated with high naevus counts. (2002) (1)
Evaluation radiologique de l'arthrose (1996) (1)
Postprandial lipemia and CVD; does the magnitude, peak concentration or duration impact intermediary cardiometabolic risk factors differentially? PREDICT I Study. (2020) (1)
PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity (2018) (1)
Heritability of the glycan clock of biological age (2022) (1)
A case-control study of oral contraceptive use in women with rheumatoid arthritis and their unaffected sisters. (1989) (1)
Variants associated with HHIP expression have sex-differential effects on lung function (2021) (1)
Hip morphology in a population based cohort of 1003 women (2012) (1)
Early menopausal bone loss at the spine is associated with polymorphisms at the interleukin 1 receptor antagonist locus but not the interleukin 6 locus (1997) (1)
Erratum: Whole-genome sequence-based analysis of thyroid function (2015) (1)
The use of genome-wide eQTL associations to identify novel genetic pathways involved in complex traits (2008) (1)
Erratum: Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants (2015) (1)
Uses of the Twins UK genetic database. (2007) (1)
PREDICTIVE ABILITY OF BIOMARKERS LINKED WITH SYNOVITIS FOR FUTURE INCIDENCE OF KNEE OSTEOARTHRITIS IN THE COMMUNITY BASED COHORT OF MIDDLE-AGE WOMEN (2017) (1)
Efficacy and safety of the cathepsin K inhibitor, ONO-5334, in the treatment of postmenopausal osteopenia or osteoporosis (2010) (1)
Causal Effects of Adiposity on Cardiovascular Risk Factors (2015) (1)
Markers associated with synovial inflammation can identify women at high risk of developing painful radiographic knee osteoarthritis: a prospective community based cohort (2018) (1)
Implementation of the simplified stochastic model of ageing for longitudinal osteoarthritis data assessment (2012) (1)
1 A heritability-based comparison of methods used to cluster 16 S rRNA gene sequences into 2 operational taxonomic units . 3 4 (2017) (1)
Hypermethylation in the ZBTB20 gene is associated with major depressive disorder (2014) (1)
Effect of Heeled Shoes on Joint Symptoms and Knee Osteoarthritis in Older Adults: A 5‐Year Follow‐Up Study (2021) (1)
Your Genes Unzipped: How your Genetic Inheritance Shapes your Life (2004) (1)
Supplementary Material 4 (2015) (1)
Prevalence and Determinants of Dry Eye Disease in a British Female Cohort (2013) (1)
Identifying optimal combinations of symptoms to trigger diagnostic work-up of suspected COVID-19 cases in vaccine trials: analysis from a community-based, prospective, observational cohort (2020) (1)
Pulse Wave Velocity Comparing Estimated and Direct Measures of Path Length in Older Women (2020) (1)
in 541 women in the general population . reproducibility and relation to x ray changes Clinical signs of early osteoarthritis : (1)
DNA methylation studies using twins: what are they telling us? (2012) (1)
Effects of 6 month lutein supplementation on macular pigment levels, measured by two methods, fundus autofluorescence and heterchromatic flicker photometry. (2006) (1)
Hip joint space width at the site of maximal joint space narrowing in Caucasian women: The Chingford study. (2003) (1)
Bone Research Society, Annual Meeting 2017 Proceedings (2018) (1)
Exome chip meta-analysis elucidates the genetic architecture of rare coding variants in smoking and drinking behavior (2017) (1)
114PHYSICAL STRENGTH PREDICTS BOTH CHANGE IN COGNITION AND BRAIN VOLUMES TEN YEARS LATER, EVEN BETWEEN IDENTICAL TWINS (2014) (1)
Contribution of heritability and epigenetic factors to skeletal muscle mass variation in UK twins (2016) (1)
Publisher Correction: Human postprandial responses to food and potential for precision nutrition (2020) (1)
Early environmental influences on vitamin D and intestinal calcium absorption (2001) (1)
Genetics of back pain (2005) (1)
080 LUMBAR DISC DEGENERATION AND GENETIC FACTORS ARE THE MAIN RISK FACTORS FOR LOW BACK PAIN: THE UK TWIN SPINE STUDY (2010) (1)
The association between low birth weight, childhood recollections of parental response to illness, and irritable bowel syndrome: a twin study (2020) (1)
Genome-wide Linkage Scan for Exercise Participation across Seven Countries Participating in the Genomeutwin Project (2007) (1)
genetic analysis Association of Common JAK 2 Variants With Body Fat , Insulin Sensitivity and Lipid Profile (2008) (1)
Erratum: Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology (The American Journal of Human Genetics (2019) 105(1) (15–28), (S0002929719301880), (10.1016/j.ajhg.2019.05.002)) (2019) (1)
Supplementary Material 9 (2013) (1)
A twin study of eczema and other atopic disorders in a large UK female population (2001) (1)
Beyond the gene roundtable discussion (2015) (1)
THE NATURAL HISTORY OF KNEE PAIN IN A PROSPECTIVE LONGITUDINAL POPULATION-BASED COHORT: HOW DOES PAIN CHANGE OVER TIME? (2010) (1)
The role of adiposity in cardiometabolic traits (2013) (1)
Genetic expression in osteoarthritis is joint specific not generalized: Evidence from a radiographic study of twins (2001) (1)
Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6 (2018) (1)
Genetic and Environmental Influences on self-reported G-Spots in Women : A (2009) (1)
Faculty Opinions recommendation of Circulating levels of IL-6 and TNF-α are associated with knee radiographic osteoarthritis and knee cartilage loss in older adults. (2010) (1)
The genetic determinants of knee disorders requiring surgery: A classical twin study (2007) (1)
Type 1 diabetes susceptibility alleles are associated with distinct alterations in the gut microbiota (2018) (1)
391 ASSOCIATION OF INTERLEUKIN-1 RECEPTOR ANTAGONIST (IL-IRN) TTC HAPLOTYPE WITH RADIOGRAPHIC KNEE OA SEVERITY IN META-ANALYSIS (2010) (1)
osteoarthritis ratio : a novel metabolomic biomarker of knee Serum branched-chain amino acid to histidine (2010) (1)
Prevalence and risk factors for symptomatic pelvic organ prolapse using the ICIQ-Vaginal Symptoms questionnaire: results from the TwinsUK adult twin registry (2013) (1)
Genome-Wide Association Analysis of Over 170,000 Individuals from the UK Biobank Identifies Seven Loci Associated with Dietary Approaches to Stop Hypertension (DASH) Diet (2022) (1)
Intergenic variants of HBSIL-MYB are responsible for a major quantitative trait locus on chromosome 6q23 influencing HbF levels in adults. (2006) (1)
Genetic Influences on Circulating Vitamin D Level: A Review (2012) (1)
The heritability of age-related cortical cataract (2001) (1)
A genome-wide scan of adult human stature and skeletal size. (2008) (1)
Epigenetics of discordant monozygotic twins: implications for disease (2014) (1)
Influence of Gut Microbial Communities on Fasting and Postprandial Lipids and Circulating Metabolites: The PREDICT 1 Study (2020) (1)
17 GENOME-WIDE ASSOCIATION SCAN OF OSTEOARTHRITIS OF THE KNEE (2007) (1)
Personal metabolic responses to food predicted using multi-omics machine learning in 1,100 twins and singletons: The PREDICT I Study. (2020) (1)
Large scale trans-ethnic meta-analyses identify novel rare and common variants associated with blood pressure and hypertension (2016) (1)
Novel variants for cartilage thickness and hip osteoarthritis: revealing genes implicated in cartilage and bone development (2014) (1)
Role and evolution of therapeutic options (2005) (1)
DNA methylation changes at infertility genes in newborn twins conceived by in vitro fertilisation (2017) (1)
The virome in adult monozygotic twins with concordant or discordant gut microbiomes (2019) (1)
Low-frequency variation in TP53 has large effects on head circumference and intracranial volume (2019) (1)
AB0962 Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: A randomized, double-blind, placebo-controlled international trial (2013) (1)
The genetic architecture of hip statistical shape models suggests that endochondral bone formation makes an important contribution to hip shape (2018) (1)
228-OR: Decoding Human Postprandial Responses to Food and Their Potential for Precision Nutrition: The PREDICT 1 Study (2020) (1)
The heritability of SOS and BMD - a comparative study between multi-site ultrasound and DXA: A twin study. (2000) (1)
Epidemiology [301–314] 301. The Population Prevalence of Foot and Ankle Pain Over the Age of 45 Years: A Systematic Review (2010) (1)
Erratum: A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans (2015) (1)
A study of osteoblast-like cells and osteoclast activity in identical twins discordant for osteoporosis (2000) (1)
Abstract 32: Novel Genetic Loci for Blood Pressure Regulation Identified by the Analysis of DNA Methylation (2016) (1)
A Genome-wide Scan for Blood Pressure Suggests Linkage to Chromosome 11, and Replication of Loci on Chromosomes 16, 17 and 22 (2004) (1)
Interrogating causal pathways linking genetic variants, small molecule metabolites, and circulating lipids (2014) (1)
Microbiota composition is moderately associated with greenspace composition in a UK cohort of twins (2021) (1)
general population : the effect of obesity . women with unilateral knee disease in the Incidence and progression of osteoarthritis in (2004) (1)
Exome-chip meta-analysis identifies novel loci, including ADAMTS6 associated with cardiac conduction (2018) (1)
METABOLIC PROFILES ASSOCIATED WITH RADIOGRAPHIC KNEE OSTEOARTHRITIS IN A POPULATION-BASED COHORT OF MIDDLE-AGED WOMEN (2016) (1)
Arterial stiffening relates to arterial calcification but not to non-calcified atheroma as determined by multimodality imaging of the aorta (2010) (1)
57FRAILTY AND THE MICROBIOME: A TWIN STUDY (2015) (1)
Human serum metabolic profiles are age dependent: Metabolic profiles associated with age (2012) (1)
Strontium Ranelate in Knee Osteoarthritis Trial (SEKOIA): A Structural and Symptomatic Efficacy. (2012) (1)
osteoarthritis progression Effects of strontium ranelate on spinal (2008) (1)
THE NATURAL HISTORY OF KNEE PAIN IN A PROSPECTIVE LONGITUDINAL POPULATION-BASED COHORT: IDENTIFYING IMPORTANT PATIENT PHENOTYPES (2010) (1)
Prevalence of Premature Ovarian Failure in Australian Twins (2007) (1)
Schmorl nodes are common, highly heritable and an independent risk factor for back pain in healthy females: A candidate gene study of twins (2002) (1)
Individuals with a genetic shift in haematological indices (2008) (1)
Peak bone mass, early menopausal bone loss and polymorphism at the oestrogen receptor gene (2006) (1)
Postprandial Responses to a Standardised Meal in Hypertension: The Mediatory Role of Visceral Fat Mass (2022) (1)
Vaccination against SARS-CoV-2 in UK school-aged children and young people decreases infection rates and reduces COVID-19 symptoms (2022) (1)
How people wake up is associated with previous night’s sleep together with physical activity and food intake (2022) (1)
Cardiometabolic health, diet and the gut microbiome: a meta-omics perspective (2023) (1)
App-based COVID-19 syndromic surveillance and prediction of hospital admissions in COVID Symptom Study Sweden (2022) (1)
Optimised Glucose “Time in Range” Using Continuous Glucose Monitors in 4,805 Non-Diabetic Individuals Is Associated With Favourable Diet and Health: The ZOE PREDICT Studies (2022) (1)
A reference map of potential determinants for the human serum metabolome (2020) (1)
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution (2019) (1)
Transcript expression-aware annotation improves rare variant interpretation (2020) (1)
Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function (2022) (1)
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (2020) (1)
Author Correction: Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes (2021) (1)
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals (2018) (1)
Relationship between genome and epigenome - challenges and requirements for future research (2014) (1)
Arthritis, estrogens and menopause (1998) (0)
A replication asociation study of candidate genes with clinical knee osteoarthritis (2005) (0)
Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure (Supplementary Data) (2018) (0)
Novel regional age-associated DNA methylation changes within human common disease-associated loci (2016) (0)
UNCOVERING ASSOCIATIONS BETWEEN BLOOD PRESSURE PHENOTYPES AND IMMUNE TRAITS IN TWINSUK (2021) (0)
Evidence for Shared Genes between Insulin Resistance and Haemostasis (2001) (0)
Correction to: Yoghurt consumption is associated with changes in the composition of the human gut microbiome and metabolome (2022) (0)
consortiumwith hand osteoarthritis: the Treat-OA locus within the ataxin 2 binding protein 1 gene is A genome-wide association study suggests that a (2009) (0)
Gene-environment interactions influence relationships between alcohol and polyunsaturated fat intakes and central abdominal fat in healthy female twins. (2003) (0)
Environmental Factors Largely Explain the Phenotypic Correlations Between Retinal Arteriolar and Venular Diameters, and Their Relationship With Blood Pressure (2009) (0)
Book Review Osteoporosis: Genetics, prevention and treatment Edited by John S. Adams and Barbara P. Lukert. 308 pp. Boston, Kluwer Academic, 1999. $180. 0-7923-8366-4 (2000) (0)
Identification of Possible Myopia Susceptibility Loci using a Genome-wide Screen in an Unselected Sample of Non-identical Twins (2003) (0)
BASELINE BUT NOT CHANGE IN BODY MASS INDEX IS A RISK FACTOR FOR BILATERAL KNEE PAIN AT 15 YEARS (2010) (0)
Correspondence (1989) (0)
Differential effects of multi-site SOS and DXA on cortical bone with HRT. (2001) (0)
Thermographic diagnosis of primary Raynaud's Phenomenon (2001) (0)
GWAS identifies 52 genomic regions associated with iris colour in a study conducted using almost 200,000 participants of European descent (2018) (0)
Precision Nutrition and Reliability of Continuous Glucose Monitors: Insights From the PREDICT Study (2021) (0)
Genotype score associated with the risk of androgenetic alopecia. (2012) (0)
Publisher Correction: Building an international consortium for tracking coronavirus health status (2020) (0)
001 NOVEL BIOMARKERS OF KNEE OSTEOARTHRITIS IDENTIFIED USING METABOLIC PROFILING (2009) (0)
Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation (2017) (0)
Genetic Analysis Common STAT 3 Variants Are Not Associated With Obesity or Insulin Resistance in Female Twins (2007) (0)
Erratum (2012) (0)
The association between statistical shape variations of the hip and the development of radiographic hip osteoarthritis within 8 years of follow-up: data from 17,738 hips in the world coach consortium. (2023) (0)
Rheumatoid arthritis. (1990) (0)
Reduction of leukocyte telomere length in hand osteoarthritis: A population based study. (2006) (0)
Acetabular Dysplasia Is A Risk Factor For Developing Radiographic Hip Osteoarthritis; Data From The World Coach Consortium (2023) (0)
Predicting the risk of fracture at any site in the skeleton: Are all BMD measurements equally effective? (2004) (0)
EVIDENCE OF GENE-NUTRITION INTERACTION CLUSTERS IN OSTEOPOROSIS (2011) (0)
The 7Q31 locus, containing WNT16, is associated with bone mineral density, osteoporotic fracture and bone strength (2012) (0)
Structural, psychological and genetic influences on low back and neck pain: a twin study (2003) (0)
Basic science232. Certolizumab pegol prevents pro-inflammatory alterations in endothelial cell function (2012) (0)
spondylitis . compression fracture rates in ankylosing Bone mineral density and vertebral (0)
The genetics of the human face: identification of large effect single gene variants (2017) (0)
Abstract 1564 3D Magnetic Resonance Imaging of Body Fat Distribution in Obese Twins From the TwinsUK Cohort: A Comparative Study to Current Cardiovascular Risk Assessment and Risk Scores (2009) (0)
Wnt16 Is associated with bone mineral density, osteoporotic fracture and bone strength: a Large-Scale Meta-Analysis of Genomewide Association Studies (2012) (0)
The St. Thomas' UK Adult Twin Registry (2002) (0)
407 A COMPARISON OF FOUR RADIOGRAPHIC SCORING METHODS FOR KNEE OSTEOARTHRITIS – SHORT AND MEDIUM TERM REPRODUCIBILITY (2011) (0)
002 IDENTIFICATION OF A NOVEL HTRA1-SUSCEPTIBLE CLEAVAGE SITE IN HUMAN AGGRECAN: EVIDENCE FOR THE INVOLVEMENT OF HTRA1 IN AGGRECAN PROTEOLYSIS IN VIVO (2009) (0)
20 COMMON GENETIC VARIATION IN THE ESTROGEN RECEPTOR BETA GENE IS ASSOCIATED WITH INCREASED RISK OF OSTEOARTHRITIS (2007) (0)
Edinburgh Research Explorer Assessment of gene-by-sex interaction effect on bone mineral density (2018) (0)
Population whole-genome bisulfite sequencing across two tissues highlights the environment as the principal source of human methylome variation (2015) (0)
Genome-wide Association Study Of Nuclear And Cortical Cataract Identifies Potential Genes And Pathways That Alter Susceptibility To The Disease (2011) (0)
372 POLYMORPHISM IN THE RUNX1 GENE ARE ASSOCIATED WITH OSTEOARTHRITIS OF THE HIP BUT NOT OF THE KNEE IN THE UK (2009) (0)
A genome-wide association study identifies a common variant near the GRP22 gene as a new locus involved in prevalence and progression of osteoarthritis (2009) (0)
Whole-genome sequencing and deep imputation identifies non-coding variants near Engrailed-1 with large effects on bone mineral density and fracture (2015) (0)
GENERALIZED OSTEOARTHRITIS IN WOMEN - DEFINITION FOR EPIDEMIOLOGIC STUDIES AND PATTERN OF JOINT INVOLVEMENT (1995) (0)
Hemochromatosis HFE mutations in osteoarthritis of the hand and knee (2004) (0)
SAT0504 Predictive ability of biomarkers linked with synovitis for future incidence of painful knee osteoarthritis in a community based cohort of middle-age women (2017) (0)
Human postprandial responses to food and potential for precision nutrition (2020) (0)
090 DNA methylation and its relationship with musculoskeletal health in older adults from the Hertfordshire Cohort Study: findings from an epigenome-wide association study (2018) (0)
Erratum to: Influence of acquired obesity on coronary vessel wall late gadolinium enhancement in discordant monozygote twins (2017) (0)
Relationship Between Lumbar Bone Density Measurements and Spinal Osteoarthritis (1993) (0)
Genetics of cutaneous traits associated with melanoma risk. A UK twin study (1998) (0)
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction (2020) (0)
Longitudinal change in vascular structure and function over a 5 year period in Twins UK Cohort (2016) (0)
Risk of Premature Ovarian Failure in Twins (2005) (0)
Are oesophageal peristaltic or lower oesophageal sphincter functions genetically determined in GORD? A discordant co-twin case control study (2006) (0)
Activation of coagulation and fibrinolytic system and thrombotic tendency (2002) (0)
osteoarthritis , and inflammatory diseases . Keratan sulphate in rheumatoid arthritis , (2004) (0)
Useofa risk factor anddietary calcium questionnaire inpredicting bonedensity and subsequent boneloss atthemenopause (1992) (0)
Integrative DNA methylome analysis of pan-cancer biomarkers in cancer discordant monozygotic twin-pairs (2016) (0)
Strontium ranelate (Protelos): new option in osteoporosis. (2005) (0)
Diagnosis by determination of polymorphisms in the promoter region of the TGF-Beta 1 gene (1997) (0)
Defining osteoarthritis ofthehandfor epidemiological studies: TheChingford Study (1994) (0)
A50a VARIATION AT THE ANP32A AND WNT5A GENES – BOTH INVOLVED IN WNT SIGNALING – IS ASSOCIATED WITH RISK OF HIP OSTEOARTHRITIS IN WOMEN (2008) (0)
380 VARIATION IN THE GENE ENCODING CYTOSOLIC GROUP IVA PHOSPHOLIPASE A2 IS ASSOCIATED WITH BOTH SYSTEMIC LUPUS ERYTHEMATOSUS AND OSTEOARTHRITIS (2009) (0)
Combining sites for fracture discrimination: results for axial transmission ultrasound compared with a theoretical model. (2003) (0)
Meta-analysis identi fi es loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide signi fi cance (2014) (0)
Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability (2018) (0)
The Genetic Basis of Peripapillary Atrophy: The Twin Eye Study (2004) (0)
Genome-screen of a healthy cohort of twin pairs reveals linkage for bone metabolism markers to chromosomes 1, 12, 17 and 19. (2003) (0)
Editorial Biomarkers in osteoarthritis (2008) (0)
RESEARCH — WOMEN ’ S SEXUAL HEALTH The Relationship Between Same-Sex Sexual Experience , Sexual Distress , and Female Sexual Dysfunctionjsm (2011) (0)
GENETIC VARIANTS NEAR INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3 (IGFBP3) ARE ASSOCIATED WITH HIP OSTEOARTHRITIS (2013) (0)
Invited review Menopause, oestrogens and arthritis (2000) (0)
NORMAL AGE RELATED COGNITIVE CHANGE IS HALF EXPLAINED BY GENES - A TWIN STUDY (2012) (0)
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Supplementary Material (nature09270-s1) (2012) (0)
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Author Correction: Postprandial glycaemic dips predict appetite and energy intake in healthy individuals (2021) (0)
Acetyl CoA carboxylase (ACACB) Promoter SNP - 8414 C/T is associated with body fat in women and affects promoter activity. (2008) (0)
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Relation of mean and pulsatile blood pressure components to atherosclerosis and arteriosclerosis: A 10-year follow-up study (2011) (0)
A locus on chromosome 8 influencing the switch from fetal to adult hemoglobin is also acting in a European Caucasian population (2005) (0)
Nontechnical Summary Returns to Education : Evidence from UK Twins (2002) (0)
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Can the WHO criteria be applied to multi-site axial transmission quantitative ultrasound? (2002) (0)
A Discordant Monozygotic Twin Approach to Testing Environmental Influences on Sexual Dysfunction in Women (2013) (0)
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18 GENETIC INFLUENCES ON OSTEOARTHRITIS: AN UPDATE (2006) (0)
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The genetics of osteoarthritis and clues to bone and cartilage biology (2010) (0)
Functional characterization of GWAS loci associated with fracture risk (2013) (0)
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Vitamin D receptor genotype and bone turnover in female twins (2006) (0)
Replication in genetic association studies - reply. (2006) (0)
The case for preventive rheumatology. (1991) (0)
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Adherence to Healthy Diet and Risk and Severity of SARS-CoV-2 Infections: A Community Survey Study Within the COVID Symptom Study Application (2021) (0)
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A55 LUMBAR DISC DISEASE SHOWS LINKAGE TO CHROMOSOME 19 (2006) (0)
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Immunological indices of patients with rheumatoid arthritis after methylprednisolone pulse therapy (0)
Interaction of Genetic Determinant of Forced Expiratory Volume with Smoking and Asthma: A Classic Twin Study (2007) (0)
Version Other version Link to publication record in King ' s Research Portal (2016) (0)
A Common Genetic Factor Underlies Hypertension, Raynaud's Phenomenon, Migraine and Coronary Artery Disease - Session: Poster (2004) (0)
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Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (2018) (0)
Genetic correlations reveal the shared genetic architecture of transcription in human peripheral blood (2017) (0)
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twin study Heritability of intraocular pressure: a classical (2008) (0)
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022 FOLLOW-UP ANALYSIS OF THE ROLE OF GENETIC VARIATION IN ADAMTS14 IN OSTEOARTHRITIS SUSCEPTIBILITY (2009) (0)
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369 OSTEOPROTEGERIN (OPG) GENE VARIANTS AND THE INCIDENCE OF KNEE OSTEOARTHRITIS IN THE CHINGFORD STUDY (2008) (0)
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Cyclical intravenous pamidronate in the treatment of severe osteoproosis for upto 6 years. (2004) (0)
Heritability of retinal vascular diameters: The Twin Eye Study (2005) (0)
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Public Attitudes to Assisted Reproduction, Gene Selection, and Human Reproductive Cloning: Important Lessons from Two Twin Studies (2007) (0)
Correction to: Yoghurt consumption is associated with changes in the composition of the human gut microbiome and metabolome (2022) (0)
Obesity Reveals an Association between Blood Pressure and the G-protein B3-Subunit Gene: Haplotype and Sib-TDT Analyses in Female Dizygotic Twins - Session: Complex Disorders I - Metabolic Syndrome, Obesity (2004) (0)
Age Differences in Genetic and Environmental Variations in Stress-Coping During Adulthood: A Study of Female Twins (2012) (0)
Genetic and environmental influences on height from infancy to early adulthood: An individual-based pooled analysis of twin (2016) (0)
A genome-wide screen for myopia susceptibility loci in twins, including a replicate sample (2003) (0)
Strontium Ranelate: the first drug in a new class for osteoporosis. (2004) (0)
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A42 A GENOME-WIDE ASSOCIATION STUDY REVEALS A NOVEL LOCUS FOR HAND OSTEOARTHRITIS (2008) (0)
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258. Epigenetic Regulation Implicated in Lumbar Disc Degeneration (2015) (0)
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Abdominal Aortic Calcification Detection Using Dual-Energy X-Ray Absorptiometry: Validation Study in Healthy Women Compared to Computed Tomography (2013) (0)
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Tu1444 Post-General Anaesthetic Nausea and Motion Sickness are Associated With Irritable Bowel Syndrome: A Twin Study (2012) (0)
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393 IDENTIFICATION OF THE GENETIC DETERMINANTS INVOLVED IN THE INITIATION OF OA (2010) (0)
346 VITAMIN D AND FALLS AND FRACTURES IN OLDER WOMEN (2011) (0)
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chromosome 2 and 19 female twin pairs showing replication of QTLs on Genomewide linkage scan of hand osteoarthritis in (2006) (0)
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Two Candidate Genes for Low Platelet Count Identified by Genome-Wide Linkage Analysis: Glycoprotein IX and Thrombopoietin. (2005) (0)
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To see the final version of this paper please visit the publisher's website. Access to the published version may require a subscription. (2010) (0)
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355 SITE AND GENDER SPECIFICITY OF 8 CANDIDATE GENES IN OSTEOARTHRITIS OF THE HIP: A STUDY OF 780 CASES AND 672 CONTROLS (2008) (0)
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023 META-ANALYSIS OF GENOME-WIDE ASSOCIATION STUDIES OF OSTEOARTHRITIS (2009) (0)
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386 ABDOMINAL AORTIC CALCIFICATION DETECTION USING DUAL X-RAY ABSORPTIOMETRY (DXA): VALIDATION STUDY IN HEALTHY WOMEN COMPARED TO COMPUTED TOMOGRAPHY (CT) (2012) (0)
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Which OA patients are at risk of subsequent progression (2004) (0)
Slower self-reported eating rate is associated with favourable cardio-metabolic risk factors in UK adults (2023) (0)
THE WORLDWIDE COLLABORATION ON OSTEOARTHRITIS PREDICTION FOR THE HIP (WORLD COACH) CONSORTIUM: DESIGN AND RATIONALE OF A CONSORTIUM USING INDIVIDUAL PARTICIPANT DATA FROM PROSPECTIVE COHORT STUDIES (2022) (0)
151 Differential DNA methylation in monozygotic twins discordant for female sexual functioning (2018) (0)
Microsoft Word-nqac237.docx (2022) (0)
ID: 204 Heritability of plasma D-dimer, clot turbidity and clot lysis in the Leeds Family Study (2006) (0)
Association of systemic lupus erythematosus associates with decreased immunosuppressive potential of the IgG glycome (2018) (0)
Dietary Intake, Serum Levels and Their Relationship With Macular Pigment in Healthy Women (2008) (0)
Genome-wide Scan for Prospective Memory Suggests Linkage to Chromosome 12 q 22 (2005) (0)
Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02 (2019) (0)
Defining the relationship between lipids and immune traits in TwinsUK (2021) (0)
SP086GLYCOSILATION PROFILE OF IMMUNOGLOBULIN G IN EARLY CHRONIC KIDNEY DISEASE (2015) (0)
Multi-omic analyses reveal antibody-dependent natural killer cell-mediated cytotoxicity in autoimmune thyroid diseases (2019) (0)
P.19 TRANSIENT LOWER OESOPHAGEAL SPHINCTER RELAXATION AND MECHANISMS OF GASTROOESOPHAGEAL REFLUX IN TWINS DISCORDANT FOR GASTROOESOPHAGEAL REFLUX SYMPTOMS (2010) (0)
Modifies the Association of Leukocyte Telomere Length with Insulin Resistance and Inflammation 05-1814-Revised (2005) (0)
Association between dheas and bone loss in postmenopausal caucasian women: A 15 years longitudinal population-based study (2010) (0)
Postprandial and Fasting Metabolic Signatures: Insights From the ZOE PREDICT 1 Study (2022) (0)
Metabolomic and gut microbiome profiles across the spectrum of community-based COVID and non-COVID disease: A COVID-19 Biobank study. (2022) (0)
THE TRIAD OF OSTEOPHYTES, ENTHESOPHYTES AND INCREASED BONE MASS MAY HELP TO DEFINE A BONE-FORMING SUB-TYPE OF OSTEOARTHRITIS (2014) (0)
University of Groningen Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index Hoggart, (2014) (0)
Baseline hip morphology and pain at 20 years - a longitudinal cohort study (2018) (0)
PPI‐Induced Changes in Plasma Metabolite Levels Influence Total Hip Bone Mineral Density in a UK Cohort (2022) (0)
Strontium ranelate decreases the risk of hip fracture over 3 and 5 years in post menopausal women at high risk (2008) (0)
Accessible data curation and analytics for international-scale citizen science datasets (2021) (0)
Whole-genome sequencing identifies non-coding variants near EN 1 with large effects on bone mineral density (2014) (0)
174: DIET AND GUT MICROBIAL INTERACTIONS IN IRRITABLE BOWEL SYNDROME SUBTYPES (2022) (0)
Social Jetlag Is Associated With Poor Diet and Increased Inflammation in the ZOE PREDICT 1 Cohort (2022) (0)
Self-reported COVID-19 vaccine hesitancy and uptake among participants from different racial and ethnic groups in the United States and United Kingdom (2022) (0)
Chingford Study . osteoporosis in the general population : the The relationship between osteoarthritis and (2004) (0)
Response to: The Microbiome: A Biological Mechanism Underpinning the Social Gradient of Musculoskeletal Conditions (2016) (0)
Characterisation of fasting and postprandial NMR metabolites: insights from the ZOE PREDICT 1 Study (2022) (0)
Comparison of Radiographic and Dexa Scan Images to Detect Spinal Osteophytes in Elderly Patients with Vertebral Osteoporosis (1994) (0)
Dietary fat composition is associated with indexes of skeletal muscle mass in women (2011) (0)
Serum concentrations of sex hormone binding globulin in lung cancer (1986) (0)
Pain sensitivity to experimentally induced pain is genetically determined: A classical twin study in adult females (2005) (0)
Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (2021) (0)
The secondary bile acid isoursodeoxycholate correlates with post-prandial lipemia, inflammation, and appetite and changes post-bariatric surgery (2023) (0)
Cognitive Change in Older Women Using a Computerised Battery: A Longitudinal Quantitative Genetic Twin Study (2013) (0)
A Co-twin Analysis of the Effect of Moderate Alcohol Consumption on Bone Mineral Density in Women - Session: Poster (2004) (0)
[OP.LB.02.07] BLOOD PRESSURE AND HEXADECANEDIOATE: DISSECTING FUNCTIONAL PATHWAYS (2016) (0)
PS-P13-6: DEFINING THE RELATIONSHIP BETWEEN IMMUNE TRAITS AND LIPIDS IN TWINSUK (2023) (0)
ABO antigen and secretor statuses are not associated with gut microbiota composition in 1,500 twins (2016) (0)
69-LB: Postprandial 2-hr Rise in Insulin Is a Strong Predictor of Glycemic Responses to Different Meals in Healthy and Prediabetic Individuals: The PREDICT I Study (2019) (0)
Associations between greenness and predicted COVID-19–like illness incidence in the United States and the United Kingdom (2023) (0)
Obligatory and facilitative allelic variation in the DNA methylome within common disease-associated loci (2018) (0)
Meta-analysis identifies novel genes influencing levels of the potential OA biomarkers sCOMP and uCTX2 (2013) (0)
Phosphoinositol-3 kinase p85 alpha regulatory subunit gene PIK3RI variants are associated with body fat in a normal female population. (2005) (0)
A genome-screen of female twins that regulates normal variation in ultrasound BUA and VOS of the calcaneus (2003) (0)
AGE-RELATED PROGRESSION OF CENTRAL BLOOD PRESSURE COMPONENTS AND THE IMPACT OF NITROVASODILATION: A PROSPECTIVE STUDY IN FEMALE TWINS: PP.22.197 (2011) (0)
The Heritability of Intra-Ocular Pressure and Corneal Hysteresis: A Classical Twin Study (2007) (0)
PLASMA N-GLYCOME AS INCIDENCE HYPERTENSION PREDICTOR (2021) (0)
Diagnostic methods and apparatus (1997) (0)
Association of obesity and severity of knee osteoarthritis is not mediated by shared genetic influences (2001) (0)
Combined tests of linkage and association of 4 SNPs in the FXIII A-subunit gene to FXIII activity levels. (2003) (0)
Genome-wide meta-analysis results for AGA in MAAN. (2012) (0)
Author Correction: Symptoms and syndromes associated with SARS-CoV-2 infection and severity in pregnant women from two community cohorts (2022) (0)
Genetic influences in swallowing disorders: a twin study. (2005) (0)
Author Correction: Evaluating drug targets through human loss-of-function genetic variation (2021) (0)
Genome-wide association studies identify DNA variants influencing eyebrow thickness variation in Europeans and across continental populations. (2023) (0)
Vaccine after Effects and Post-Vaccine Infection in a Real World Setting: Results from the COVID Symptom Study App (2021) (0)
Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals (2021) (0)
Vaccine after Effects and Post-Vaccine Infection in a Real World Setting: Results from the COVID Symptom Study App (2021) (0)
PRIVERZhENNOST' K LEChENIYu OSTEOPOROZA: VOPROSPERENOSIMOSTI, REZhIMA LEChENIYaILI ISKLYuChITEL'NO KhOROShEGO DIALOGA S PATsIENTOM? (2010) (0)
Linkage of myopia to PAX6 in an unselected twin sample (2004) (0)
Menopause Is a Key Factor Influencing Postprandial Metabolism, Metabolic Health and Lifestyle: The ZOE PREDICT Study (2022) (0)
Interplay between the (Poly)phenol Metabolome, Gut Microbiome, and Cardiovascular Health in Women: A Cross-Sectional Study from the TwinsUK Cohort (2023) (0)
Two Distinct Genetic Mechanisms Modify the Level of HbA(2) in Peripheral Blood (2011) (0)
Genome-wide Linkage Scan for 25-OH Vitamin D Serum Level in a Female Caucasian Population (2007) (0)
Hip Radiographic Image-derived Morphometric and Trabecular Structural Phenotypes in a Large Group of Dizygotic Twin Pairs: Methodology (2007) (0)
Building an international consortium for tracking coronavirus health status (2020) (0)
Genetic dissection of fetal hemoglobin levels in adults (2005) (0)
DIETARY INFLUENCE OF SYSTOLIC AND DIASTOLIC BLOOD PRESSURE IN THE TWINSUK COHORT (2021) (0)
Publisher Correction: Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability (2019) (0)
Is IVA a reliable method of detecting vertebral fractures (2006) (0)
71-LB: Personal Metabolic Responses to Food Predicted Using Multi-omics Machine Learning: The PREDICT I Study (2019) (0)
THE arcOGEN CONSORTIUM: STAGE 1 OF A GENOME-WIDE ASSOCIATION SCAN FOR OSTEOARTHRITIS (2010) (0)
For the love of Greece (2007) (0)
Author Correction: Transcript expression-aware annotation improves rare variant interpretation (2021) (0)
Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure (2018) (0)
Author Correction: A structural variation reference for medical and population genetics (2021) (0)
THE GENETICS OF FEMALE SEXUAL BEHAVIOR (2008) (0)
The fecal metabolome as a functional readout of the gut microbiome (2018) (0)
Omega-3 fatty acids correlate with gut microbiome diversity and production of N-carbamylglutamate in middle aged and elderly women (2017) (0)
Targeted metabolomics profiles are strongly correlated with nutritional patterns in women (2012) (0)
Serum Lipid Levels and Risk Of Hand Osteoarthritis: The Chingford Prospective Cohort Study (2017) (0)
An expedition into the future of food (2019) (0)
Genetic factors in osteoporosis. (2004) (0)
Metabolomic Profiling of Age-Related Cataract (2012) (0)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2019) (0)
Molecular genetic overlap between migraine and major depressive disorder (2018) (0)
University of Southern Denmark Zygosity Differences in Height and Body Mass Index of Twins From Infancy to Old Age (2015) (0)
WHAT SHOULD YOU EAT TO BOOST YOUR IMMUNE SYSTEM? (2023) (0)
The BRC Allergene Project: heritability of nickel allergy and genetic determinants (2013) (0)
A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine (2020) (0)
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors (2019) (0)
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals (2018) (0)
Epigenetic associations of type 2 diabetes and BMI in an Arab population (2016) (0)
Leveraging high-dimensional flow cytometry to reveal the human immune system at a population-wide scale (2021) (0)
Author Correction: GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability (2019) (0)
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes (2018) (0)
Mapping of the gene network that regulates glycan clock of ageing (2023) (0)
Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals (2020) (0)
Detecting Bone Size Quantitative Trait Loci Using DXA Imaging (2007) (0)
A structural variation reference for medical and population genetics (2020) (0)
Circulating metabolic biomarkers of renal function in diabetic and non-diabetic populations (2018) (0)
Addendum: The mutational constraint spectrum quantified from variation in 141,456 humans (2021) (0)
S202 A GENOME WIDE ASSOCIATION STUDY ON CHRONIC WIDESPREAD PAIN: EVIDENCE FOR INVOLVEMENT OF THE 5P15.2 REGION (2011) (0)
The effect of LRRK2 loss-of-function variants in humans (2020) (0)
Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (2018) (0)
SP017CIRCULATING HNMR BASED METABOLOMIC PROFILE ASSOCIATED TO PROTEINURIA IN DIABETIC PATIENT (2017) (0)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (0)
Postprandial glycaemic dips predict appetite and energy intake in healthy individuals (2021) (0)
Evaluating drug targets through human loss-of-function genetic variation (2020) (0)
PAINFUL KNEE BUT NOT HAND OSTEOARTHRITIS PREDICTS EXCESS MORTALITY IN A COMMUNITY-BASED COHORT OF MIDDLE-AGED WOMEN WITH 23 YEARS OF FOLLOW-UP (2015) (0)
The safety and efficancy of PTH in women receiving hormone therapy. (2005) (0)
Total serum N-glycans associate with response to immune checkpoint inhibition therapy and survival in patients with advanced melanoma (2023) (0)
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative (2018) (0)
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative (2018) (0)
The mutational constraint spectrum quantified from variation in 141,456 humans (2020) (0)
Genome-wide methylation analysis identifies ELOVL5 as an epigenetic biomarker for the risk of type 2 diabetes mellitus (2018) (0)
Radiological progression ofosteoarthritis: an 11year follow up study oftheknee (1992) (0)
Gene expression analysis identify genes associated with arterial stiffness and carotid diameter in the twins UK cohort (2014) (0)
A genetic interaction between chromosome 8q and the beta-globin complex influences the switch from fetal to adult hemoglobin. (2003) (0)
Treatment perspectives for gut microbiota (2016) (0)
Selection and evaluation of tagging single nucleotide polymorphisms in the protein tyrosine phosphatase 1B gene (2005) (0)
The First ‘Classical’ Twin Study? Analysis of Refractive Error Using Monozygotic and Dizygotic Twins Published in 1922 (2005) (0)
Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study Supplementary methods (2008) (0)
Re : Female Sexual Function before and after Bariatric Surgery : A Cross-Sectional Study and Review of Literature (2015) (0)
The Relation Between Insulin Resistance and Hemostasis: Pleiotropic Genes and Common Environment (2003) (0)
O37. The Autoimmune Risk Gene UBE2L3 is Highly Expressed During B Cell Proliferation and is Correlated with Plasmablast and Plasma Cell Expansion in SLE (2015) (0)
Biomarkers of skin ageing using genome wide transcriptomics (2011) (0)
Biomarker (UKPIO number 1402166.1) (2014) (0)
Visibility of thoracic vertebra using instant vertebral assessment is dependent on hip boone mineral density (2006) (0)
Genome Wide Association Study (GWAS) Identifies Genetic Variants on Chromosome 15 Associated With Refractive Error (2010) (0)
Genetically determined dopamine levels are associated with obesity (2004) (0)
University of Groningen Common Genetic Variation Near the Phospholamban Gene Is Associated with Cardiac Repolarisation (2018) (0)
Self-reported Anxiety Sensitivity Index in the TwinsUK cohort (2019) (0)
Correction: Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses (2016) (0)
Ensemble landmarking of 3D facial surface scans (2018) (0)
Genetic influences in non-cardiac chest pain: a twin study. (2005) (0)
The Effect of Repeated Measurements on Heritability: A Twin Study (2008) (0)
Chingford study . in women in the general population : the Cigarette smoking and risk of osteoarthritis (2004) (0)
Whole-genome sequence-based analysis of thyroid function (vol 6, 5681, 2015) (2015) (0)
A novel quantitative trait locus controlling fetal haemoglobin on chromosome 2p15 (2008) (0)
Correction: Identification of PLCL1 Gene for Hip Bone Size Variation in Females in a Genome-Wide Association Study (2009) (0)
Publisher Correction: Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways (2019) (0)
Osteoporosis - NICE sets new challenges for London. (2004) (0)
A Genome-Wide Linkage Scan for Age at Menarche in Three Populations of (2008) (0)
Abstract 12890: Heritability of Daily Physical Activity as Assessed by Combined Heart Rate and Movement Sensing in 771 Same-Sex Twin Pairs (2012) (0)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (0)
Running title: Pfeiffer et al.; genome-wide DNA methylation and blood lipid levels (2015) (0)
99THE ROCKWOOD FRAILTY INDEX IN TWINSUK (2014) (0)
GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability (2018) (0)

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