Tim Stearns
#68,879
Most Influential Person Now
American biologist
Tim Stearns's AcademicInfluence.com Rankings
Tim Stearnsbiology Degrees
Biology
#2898
World Rank
#4525
Historical Rank
#1241
USA Rank
Cell Biology
#183
World Rank
#190
Historical Rank
#46
USA Rank
Molecular Biology
#959
World Rank
#982
Historical Rank
#196
USA Rank
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Biology
Tim Stearns's Degrees
- PhD Biological Sciences University of California, San Francisco
- Bachelors Biology University of California, Santa Cruz
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Why Is Tim Stearns Influential?
(Suggest an Edit or Addition)According to Wikipedia, Tim Stearns is an American biologist and university administrator, and is the Dean of Graduate and Postgraduate Studies, Vice President of Education, and Head of Laboratory at The Rockefeller University. Stearns was formerly the Frank Lee and Carol Hall Professor in the Department of Biology at Stanford University, with appointments in the Department of Genetics and the Cancer Center in the Stanford Medical School. Stearns served as chair of the Department of Biology at Stanford as well as Acting Dean of Research and Senior Associate Vice Provost of Research. Stearns is an HHMI Professor, and is a member of JASON, a scientific advisory group. He has served on the editorial boards of The Journal of Cell Biology, Genetics and Molecular Biology of the Cell.
Tim Stearns's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- γ-Tubulin is a highly conserved component of the centrosome (1991) (613)
- The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries (2011) (541)
- Fluorescence microscopy methods for yeast. (1989) (534)
- Microtubules Orient the Mitotic Spindle in Yeast through Dynein-dependent Interactions with the Cell Cortex (1997) (492)
- Cyclin-dependent kinase control of centrosome duplication. (1999) (462)
- Mechanism limiting centrosome duplication to once per cell cycle (2006) (455)
- In vitro reconstitution of centrosome assembly and function: The central role of γ-tubulin (1994) (438)
- Microtubule-organizing centres: a re-evaluation (2007) (420)
- Methods in yeast genetics (2013) (367)
- Autophagy Promotes Primary Ciliogenesis by Removing OFD1 from Centriolar Satellites (2013) (323)
- DNA topoisomerase II must act at mitosis to prevent nondisjunction and chromosome breakage (1989) (322)
- ADP-ribosylation factor is functionally and physically associated with the Golgi complex. (1990) (321)
- GCP-WD is a γ-tubulin targeting factor required for centrosomal and chromatin-mediated microtubule nucleation (2006) (317)
- Polo kinase and separase regulate the mitotic licensing of centriole duplication in human cells. (2009) (296)
- Cep152 interacts with Plk4 and is required for centriole duplication (2010) (267)
- Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism (2007) (253)
- ADP ribosylation factor is an essential protein in Saccharomyces cerevisiae and is encoded by two genes (1990) (224)
- A crucial requirement for Hedgehog signaling in small cell lung cancer (2011) (223)
- The Mammalian γ-Tubulin Complex Contains Homologues of the Yeast Spindle Pole Body Components Spc97p and Spc98p (1998) (215)
- Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle. (1999) (208)
- Centrosome number is controlled by a centrosome-intrinsic block to reduplication (2003) (208)
- Plk1-Dependent Recruitment of γ-Tubulin Complexes to Mitotic Centrosomes Involves Multiple PCM Components (2009) (206)
- Chromosome instability mutants of Saccharomyces cerevisiae that are defective in microtubule-mediated processes. (1990) (199)
- Tubulin Subunits Exist in an Activated Conformational State Generated and Maintained by Protein Cofactors (1997) (199)
- Molecular characterization of centriole assembly in ciliated epithelial cells (2007) (191)
- A High-Enrollment Course-Based Undergraduate Research Experience Improves Student Conceptions of Scientific Thinking and Ability to Interpret Data (2015) (186)
- Unlinked noncomplementation: isolation of new conditional-lethal mutations in each of the tubulin genes of Saccharomyces cerevisiae. (1988) (181)
- Controlling centrosome number: licenses and blocks. (2006) (176)
- Proximity Interactions among Centrosome Components Identify Regulators of Centriole Duplication (2014) (176)
- GCP5 and GCP6: Two New Members of the Human γ-Tubulin Complex (2001) (175)
- Analysis of Tub4p, a yeast gamma-tubulin-like protein: implications for microtubule-organizing center function (1996) (172)
- Yeast mutants sensitive to antimicrotubule drugs define three genes that affect microtubule function. (1990) (166)
- Adenomatous polyposis coli and EB1 localize in close proximity of the mother centriole and EB1 is a functional component of centrosomes (2004) (161)
- Insights into microtubule nucleation from the crystal structure of human γ-tubulin (2005) (157)
- Centriole Age Underlies Asynchronous Primary Cilium Growth in Mammalian Cells (2009) (156)
- Mammalian cells lack checkpoints for tetraploidy, aberrant centrosome number, and cytokinesis failure (2005) (140)
- The centriole duplication cycle (2014) (140)
- δ-Tubulin and ɛ-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function (1999) (135)
- The centriolar satellite proteins Cep72 and Cep290 interact and are required for recruitment of BBS proteins to the cilium (2012) (131)
- Parallel analysis of genetic selections using whole genome oligonucleotide arrays. (1998) (130)
- Transcriptional Program of Ciliated Epithelial Cells Reveals New Cilium and Centrosome Components and Links to Human Disease (2012) (127)
- Cilium structure, assembly, and disassembly regulated by the cytoskeleton (2018) (124)
- Centrosome reduction during mouse spermiogenesis. (1998) (122)
- In vitro reconstitution of centrosome assembly and function: the central role of gamma-tubulin. (1994) (119)
- Supernumerary Centrosomes Nucleate Extra Cilia and Compromise Primary Cilium Signaling (2012) (115)
- ɛ-Tubulin is required for centriole duplication and microtubule organization (2003) (115)
- Specificity domains distinguish the Ras-related GTPases Ypt1 and Sec4 (1993) (109)
- STED microscopy with optimized labeling density reveals 9-fold arrangement of a centriole protein. (2012) (107)
- Mechanosensing by the Primary Cilium: Deletion of Kif3A Reduces Bone Formation Due to Loading (2012) (105)
- Cep120 is asymmetrically localized to the daughter centriole and is essential for centriole assembly (2010) (100)
- Centrosomes Isolated from Spisula solidissima Oocytes Contain Rings and an Unusual Stoichiometric Ratio of α/β Tubulin (1997) (100)
- GCP5 and GCP6: two new members of the human gamma-tubulin complex. (2001) (97)
- Myb promotes centriole amplification and later steps of the multiciliogenesis program (2013) (92)
- Centrosome Duplication A Centriolar Pas de Deux (2001) (88)
- Investigate the origins of COVID-19 (2021) (88)
- Mutational Analysis of Saccharomyces cerevisiae ARF1(*) (1995) (83)
- Centrosomal deployment of gamma-tubulin and pericentrin: evidence for a microtubule-nucleating domain and a minus-end docking domain in certain mouse epithelial cells. (1997) (80)
- Motoring to the Finish: Kinesin and Dynein Work Together to Orient the Yeast Mitotic Spindle (1997) (79)
- Manipulating yeast genome using plasmid vectors. (1990) (79)
- Primary Cilia: Cellular Sensors for the Skeleton (2008) (76)
- The Cell Center at 100 (1997) (73)
- Proteomic analysis of mammalian sperm cells identifies new components of the centrosome (2014) (72)
- Insights into microtubule nucleation from the crystal structure of human gamma-tubulin. (2005) (68)
- Delta-tubulin and epsilon-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function. (2000) (66)
- Mouse Phenome Database: an integrative database and analysis suite for curated empirical phenotype data from laboratory mice (2017) (65)
- Arrest, adaptation, and recovery following a chromosome double-strand break in Saccharomyces cerevisiae. (2000) (65)
- Alf1p, a CLIP-170 Domain-containing Protein, Is Functionally and Physically Associated with α-Tubulin (1999) (57)
- Primary cilium loss in mammalian cells occurs predominantly by whole-cilium shedding (2019) (57)
- Mouse Phenome Database: a data repository and analysis suite for curated primary mouse phenotype data (2019) (55)
- Cby1 promotes Ahi1 recruitment to a ring-shaped domain at the centriole–cilium interface and facilitates proper cilium formation and function (2014) (54)
- Probing mammalian centrosome structure using BioID proximity-dependent biotinylation. (2015) (50)
- Regulation of cilia abundance in multiciliated cells (2018) (50)
- The Rilp-like proteins Rilpl1 and Rilpl2 regulate ciliary membrane content (2013) (50)
- γ-Tubulin complexes: size does matter (1999) (50)
- FOP Is a Centriolar Satellite Protein Involved in Ciliogenesis (2013) (48)
- Curcumin Inhibits Growth of Saccharomyces cerevisiae through Iron Chelation (2011) (44)
- Zeta-Tubulin Is a Member of a Conserved Tubulin Module and Is a Component of the Centriolar Basal Foot in Multiciliated Cells (2015) (42)
- Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging. (2021) (41)
- The DNA damage checkpoint signal in budding yeast is nuclear limited. (2000) (40)
- Systematic discovery of Short Linear Motifs decodes calcineurin phosphatase signaling (2019) (39)
- Motional dynamics of single Patched1 molecules in cilia are controlled by Hedgehog and cholesterol (2019) (39)
- Nucleation and capture of large cell surface‐associated microtubule arrays that are not located near centrosomes in certain cochlear epithelial cells (1998) (37)
- Synaptically coupled central nervous system neurons lack centrosomal γ-tubulin (1997) (36)
- The cytoskeleton of Saccharomyces cerevisiae. (1990) (34)
- Centriole triplet microtubules are required for stable centriole formation and inheritance in human cells (2017) (33)
- gamma-Tubulin. (2020) (32)
- Cyclin-dependent kinase control of motile ciliogenesis (2018) (31)
- Observing planar cell polarity in multiciliated mouse airway epithelial cells. (2015) (30)
- Correction for Malone et al., Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism (2008) (29)
- 1 The Yeast Cytoskeleton (1997) (29)
- Diverse biological functions of small GTP-binding proteins in yeast. (1988) (28)
- Synaptically coupled central nervous system neurons lack centrosomal gamma-tubulin. (1997) (24)
- The Mammalian g-Tubulin Complex Contains Homologues of the Yeast Spindle Pole Body Components Spc 97 p and Spc 98 p (1998) (23)
- CRISPR/Cas9 treatment causes extended TP53-dependent cell cycle arrest in human cells (2019) (23)
- Pocket similarity identifies selective estrogen receptor modulators as microtubule modulators at the taxane site (2019) (23)
- Revealing Nanoscale Morphology of the Primary Cilium Using Super-Resolution Fluorescence Microscopy (2018) (22)
- Gamma-tubulin complexes: size does matter. (1999) (22)
- Systematic structure-function analysis of the small GTPase Arf1 in yeast. (2002) (22)
- Hedgehog signaling and the primary cilium: implications for spatial and temporal constraints on signaling. (2021) (20)
- Myb promotes centriole amplification and later steps of the multiciliogenesis program (2013) (20)
- MDM1 is a microtubule-binding protein that negatively regulates centriole duplication (2015) (19)
- The centrosome (1999) (18)
- Primary cilia in bone. (2007) (17)
- Cytoskeleton: Microtubule nucleation takes shape (1996) (17)
- Spindle positioning and cell polarity (1992) (17)
- Using yeast to determine the functional consequences of mutations in the human p53 tumor suppressor gene: An introductory course‐based undergraduate research experience in molecular and cell biology (2016) (16)
- The life cycle of centrioles. (2010) (16)
- Expression of Amino- and Carboxyl-terminal γ- and α-Tubulin Mutants in Cultured Epithelial Cells* (1998) (16)
- The ABCs of Centriole Architecture: The Form and Function of Triplet Microtubules. (2017) (15)
- Transient Primary Cilia Mediate Robust Hedgehog Pathway-Dependent Cell Cycle Control (2019) (15)
- Aging-Associated Decrease in the Histone Acetyltransferase KAT6B is Linked to Altered Hematopoietic Stem Cell Differentiation. (2020) (14)
- The yeast microtubule cytoskeleton: genetic approaches to structure and function. (1990) (14)
- The nucleus serves as the pacemaker for the cell cycle (2020) (13)
- Exploring the pole: an EMBO conference on centrosomes and spindle pole bodies (2008) (11)
- Remembrance of Cilia Past (2013) (10)
- STED super-resolution microscopy in Drosophila tissue and in mammalian cells (2011) (10)
- Centrosome-Kinase Fusions Promote Oncogenic Signaling and Disrupt Centrosome Function in Myeloproliferative Neoplasms (2014) (10)
- Cytoskeleton: Anatomy of an organizing center (1997) (9)
- Cytoskeletal dynamics in yeast. (1999) (9)
- Centrioles are amplified in cycling progenitors of olfactory sensory neurons (2020) (8)
- Growth disadvantage associated with centrosome amplification drives population-level centriole number homeostasis (2020) (8)
- Cell-Extrinsic Stressors from the Aging Bone Marrow (BM) Microenvironment Promote Dnmt3a-Mutant Clonal Hematopoiesis. (2019) (8)
- Stem cells: A fateful age gap (2009) (8)
- Sperm Centrosomes: Kiss Your Asterless Goodbye, for Fertility’s Sake (2015) (7)
- The Tubulin Superfamily (2005) (7)
- The green revolution Green fluorescent protein allows gene expression and protein localization to be observed in living cells. (1995) (6)
- Cilium axoneme internalization and degradation in chytrid fungi (2020) (6)
- The form and the substance (1995) (6)
- Long-range migration of centrioles to the apical surface of the olfactory epithelium (2021) (5)
- At the heart of the organizing center (1991) (4)
- Quick Guide: γ-Tubulin (2002) (3)
- The centrosome yields its secrets (2004) (3)
- The primary cilium: what once did nothing, now does everything. (2007) (3)
- Cellular structures. (1992) (3)
- Using femtosecond laser subcellular surgery to studycell biology (2004) (3)
- Hematopoietic Stem and Progenitor Cell Aging is Initiated at Middle Age Through Decline in Local Insulin-Like Growth Factor 1 (IGF1) (2020) (3)
- Cell architecture: putting the building blocks together. (2013) (3)
- Heterogeneous Dynamics and Mechanisms of Primary Cilium Disassembly in Mammalian Cells (2018) (3)
- Assaying Cell Cycle Progression via Flow Cytometry in CRISPR/Cas9-Treated Cells. (2021) (2)
- Centrioles, in absentia (2015) (2)
- Centrosome Biology: A SAS-sy Centriole in the Cell Cycle (2003) (2)
- Quantifying Nanoscale Morphological Features of the Primary Cilium Membrane using Super-Resolution Fluorescence Microscopy (2018) (2)
- Crystal Structure of gamma-tubulin bound to GTP (2005) (2)
- Postmitotic centriole disengagement and maturation leads to centrosome amplification in polyploid trophoblast giant cells (2022) (2)
- Mitosis sans Mitosis: The Mitotic Oscillator in Differentiation. (2017) (2)
- Calcineurin associates with centrosomes and regulates cilia length maintenance (2022) (1)
- Journey to the center of the centrosome. (2014) (1)
- Author response: Regulation of cilia abundance in multiciliated cells (2019) (1)
- Basal Body Components Exhibit Differential Protein Dynamics during Nascent Basal Body Assembly (2009) (1)
- Aging-Associated Decrease in the Histone Acetyltransferase KAT6B Causes Myeloid-Biased Hematopoietic Stem Cell Differentiation (2019) (1)
- Chromosome instability mutants of Saccharomyces cerevisiae that are defective in microtubule-mediated processes (1990) (1)
- Primary Cilium Disassembly in Mammalian Cells Occurs Predominantly by Whole-Cilium Shedding (2018) (1)
- Dnmt3a Mutation Confers a Selective Advantage Specifically to Cells within the Long-Term Hematopoietic Stem Cell (LT-HSC) Compartment (2019) (1)
- Spindle assembly checkpoint-dependent mitotic delay is required for cell division in absence of centrosomes (2022) (0)
- Decision letter: Functional partitioning of a liquid-like organelle during assembly of axonemal dyneins (2020) (0)
- In Vitro Reconstitution of Centmmm and Function : The Central Rde of y = Tubuiin (2003) (0)
- Decision letter: Genetic transformation of Spizellomyces punctatus, a resource for studying chytrid biology and evolutionary cell biology (2019) (0)
- Primary Cilia as Sensors of Mechanical Loading (2006) (0)
- Npm1ca Overcomes the Differentiation Block of DNMT3A-Mutant LT-HSCs to Transition MDS to Myeloproliferative Disorder (2018) (0)
- in Yeast Diverse Biological Functions of Small GTP-binding Proteins (2008) (0)
- DNA Topoisomerase II MustActatMitosis ToPrevent Nondisjunction andChromosome Breakage (1989) (0)
- ADP-ribosylation factor is functionally and physically associated with the Golgi complex (protein transport/GTP-binding protein/yeast/endoplasmic reticulum) (2016) (0)
- MAP9/MAPH-9 supports axonemal microtubule doublets and modulates motor movement (2023) (0)
- Mutation in DNA Methyltransferase DNMT3A Confers Enhanced Self-Renewal Capacity Onto Multipotent Progenitor Cells and Predisposes to Acute Myeloid Leukemia (AML) (2018) (0)
- Current Biology Dispatches SpermCentrosomes : KissYourAsterlessGoodbye , for Fertility ’ s Sake (0)
- The Molecular Logic of the Centrosome Duplication Cycle (2007) (0)
- Centrioles are amplified via rosette formation in cycling progenitors of olfactory sensory neurons (2019) (0)
- Departments of Biological Sciences and Genetics (2001) (0)
- Crystal structure of human gamma-tubulin bound to GTPgammaS (2005) (0)
- Author response: Cyclin-dependent kinase control of motile ciliogenesis (2018) (0)
- A not-so-simple twist of fate. (2021) (0)
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Tim Stearns is affiliated with the following schools:
