Tina Henkin
Microbiologist
Tina Henkin's AcademicInfluence.com Rankings
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Biology
Tina Henkin's Degrees
- PhD Microbiology University of California, Berkeley
- Bachelors Biology University of California, Berkeley
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(Suggest an Edit or Addition)According to Wikipedia, Tina M. Henkin is a professor of microbiology, Distinguished University Professor, and Robert W. and Estelle S. Bingham Professor of Biological Sciences at Ohio State University. She is a Fellow of the American Association for the Advancement of Science and the American Academy of Microbiology, and was elected as a member of the American Academy of Arts and Sciences and the National Academy of Sciences. In 2019, she was reappointed to her Bingham professorship. Henkin researches how bacterial cells modulate gene expression in response to changes in their environment through effects on RNA structure via RNA regulatory elements called riboswitches, primarily using Bacillus subtilis as a model. She is coauthor of the bacterial genetics textbook Snyder & Champness Molecular Genetics of Bacteria, published by the American Society of Microbiology Press.
Tina Henkin's Published Works
Published Works
- Catabolite repression of α amylase gene expression in Bacillus subtilis involves a trans‐acting gene product homologous to the Escherichia coli lacl and galR repressors (1991) (350)
- Glu-tRNAGln amidotransferase: a novel heterotrimeric enzyme required for correct decoding of glutamine codons during translation. (1997) (296)
- The S box regulon: a new global transcription termination control system for methionine and cysteine biosynthesis genes in Gram‐positive bacteria (1998) (287)
- Riboswitch RNAs: using RNA to sense cellular metabolism. (2008) (274)
- Regulation by transcription attenuation in bacteria: how RNA provides instructions for transcription termination/antitermination decisions. (2002) (260)
- Transcription termination control of the S box system: Direct measurement of S-adenosylmethionine by the leader RNA (2003) (257)
- tRNA as a positive regulator of transcription antitermination in B. subtilis (1993) (252)
- The role of CcpA transcriptional regulator in carbon metabolism in Bacillus subtilis. (1996) (205)
- The SMK box is a new SAM-binding RNA for translational regulation of SAM synthetase (2006) (192)
- The L box regulon: Lysine sensing by leader RNAs of bacterial lysine biosynthesis genes (2003) (186)
- Riboswitch-Mediated Gene Regulation: Novel RNA Architectures Dictate Gene Expression Responses. (2016) (159)
- Regulation of the Bacillus subtilis acetate kinase gene by CcpA (1993) (156)
- Identification of genes involved in utilization of acetate and acetoin in Bacillus subtilis (1993) (156)
- Crystal structures of the SAM-III/SMK riboswitch reveal the SAM-dependent translation inhibition mechanism (2008) (149)
- The T box mechanism: tRNA as a regulatory molecule (2010) (142)
- Biochemical Features and Functional Implications of the RNA-Based T-Box Regulatory Mechanism (2009) (141)
- From Ribosome to Riboswitch: Control of Gene Expression in Bacteria by RNA Structural Rearrangements (2006) (137)
- Control of Acetyl-Coenzyme A Synthetase (AcsA) Activity by Acetylation/Deacetylation without NAD+ Involvement in Bacillus subtilis (2006) (121)
- tRNA-mediated transcription antitermination in vitro: Codon–anticodon pairing independent of the ribosome (2002) (120)
- The GA motif: an RNA element common to bacterial antitermination systems, rRNA, and eukaryotic RNAs. (2001) (116)
- Interaction between the acceptor end of tRNA and the T box stimulates antitermination in the Bacillus subtilis tyrS gene: a new role for the discriminator base (1994) (116)
- Catabolite regulation of Bacillus subtilis acetate and acetoin utilization genes by CcpA (1994) (114)
- Analysis of the Bacillus subtilis tyrS gene: conservation of a regulatory sequence in multiple tRNA synthetase genes (1992) (112)
- Control of transcription termination in prokaryotes. (1996) (111)
- MotPS is the stator‐force generator for motility of alkaliphilic Bacillus, and its homologue is a second functional Mot in Bacillus subtilis (2004) (106)
- The T box and S box transcription termination control systems. (2003) (104)
- Natural Variability in S-Adenosylmethionine (SAM)-Dependent Riboswitches: S-Box Elements in Bacillus subtilis Exhibit Differential Sensitivity to SAM In Vivo and In Vitro (2007) (103)
- Riboswitch RNAs: Regulation of gene expression by direct monitoring of a physiological signal (2010) (100)
- Catabolite repression-resistant mutations of the Bacillus subtilis alpha-amylase promoter affect transcription levels and are in an operator-like sequence. (1987) (97)
- Faculty Opinions recommendation of tRNomics: analysis of tRNA genes from 50 genomes of Eukarya, Archaea, and Bacteria reveals anticodon-sparing strategies and domain-specific features. (2002) (96)
- Transcription termination control in bacteria. (2000) (95)
- Conservation of a transcription antitermination mechanism in aminoacyl-tRNA synthetase and amino acid biosynthesis genes in gram-positive bacteria. (1994) (93)
- Regulation of gene expression by effectors that bind to RNA. (2004) (90)
- SAM recognition and conformational switching mechanism in the Bacillus subtilis yitJ S box/SAM-I riboswitch. (2010) (87)
- Micro Review tRNA‐dircted transcription antitermination (1994) (87)
- Transcriptional Activation of the Bacillus subtilis ackA Gene Requires Sequences Upstream of the Promoter (1998) (83)
- Sequence requirements for terminators and antiterminators in the T box transcription antitermination system: disparity between conservation and functional requirements. (2002) (73)
- T box RNA decodes both the information content and geometry of tRNA to affect gene expression (2013) (70)
- Analysis of cis‐acting sequence and structural elements required for antitermination of the Bacillus subtilis tyrS gene (1997) (70)
- A tertiary structural element in S box leader RNAs is required for S‐adenosylmethionine‐directed transcription termination (2005) (69)
- S-adenosylmethionine directly inhibits binding of 30S ribosomal subunits to the SMK box translational riboswitch RNA (2007) (68)
- Structural transitions induced by the interaction between tRNA(Gly) and the Bacillus subtilis glyQS T box leader RNA. (2005) (67)
- Faculty Opinions recommendation of rRNA promoter regulation by nonoptimal binding of sigma region 1.2: an additional recognition element for RNA polymerase. (2006) (59)
- The rpsD gene, encoding ribosomal protein S4, is autogenously regulated in Bacillus subtilis (1991) (58)
- tRNA-directed transcription antitermination. (1994) (57)
- Solution structure of the Bacillus subtilis T-box antiterminator RNA: seven nucleotide bulge characterized by stacking and flexibility. (2003) (56)
- Molecular basis of gene regulation by the THI‐box riboswitch (2007) (54)
- Monitoring uncharged tRNA during transcription of the Bacillus subtilis glyQS gene. (2005) (53)
- Specificity of tRNA-mRNA interactions in Bacillus subtilis tyrS antitermination (1997) (53)
- Kinetic Analysis of tRNA-Directed Transcription Antitermination of the Bacillus subtilis glyQS Gene In Vitro (2004) (53)
- Tuning riboswitch regulation through conformational selection. (2011) (53)
- Prediction of Gene Function in Methylthioadenosine Recycling from Regulatory Signals (2002) (48)
- tRNA requirements for glyQS antitermination: a new twist on tRNA. (2003) (48)
- Cloning and analysis of the spc ribosomal protein operon of Bacillus subtilis: comparison with the spc operon of Escherichia coli. (1989) (47)
- In vitro structure-function studies of the Bacillus subtilis tyrS mRNA antiterminator: evidence for factor-independent tRNA acceptor stem binding specificity. (2002) (47)
- In vitro approaches to analysis of transcription termination. (2009) (45)
- 4,5-Disubstituted oxazolidinones: High affinity molecular effectors of RNA function. (2008) (45)
- Bacillus subtilis ccpA Gene Mutants Specifically Defective in Activation of Acetoin Biosynthesis (2000) (44)
- The T box riboswitch: A novel regulatory RNA that utilizes tRNA as its ligand. (2014) (44)
- Mechanisms of resistance to an amino acid antibiotic that targets translation. (2007) (43)
- Direct Evidence for Control of the Pheromone-Inducible prgQ Operon of Enterococcus faecalis Plasmid pCF10 by a Countertranscript-Driven Attenuation Mechanism (2010) (41)
- Sensing metabolic signals with nascent RNA transcripts: the T box and S box riboswitches as paradigms. (2006) (40)
- Transcriptional Activation of the Bacillus subtilis ackA Promoter Requires Sequences Upstream of the CcpA Binding Site (2001) (40)
- Metabolic Imbalance and Sporulation in an Isocitrate Dehydrogenase Mutant of Bacillus subtilis (1999) (40)
- Characterization of the Bacillus subtilis rpsD regulatory target site (1992) (39)
- Synthesis of Serine, Glycine, Cysteine, and Methionine (2002) (38)
- Variable sequences outside the SAM-binding core critically influence the conformational dynamics of the SAM-III/SMK box riboswitch. (2011) (37)
- The SAM‐responsive SMK box is a reversible riboswitch (2010) (37)
- T box riboswitches in Actinobacteria: Translational regulation via novel tRNA interactions (2015) (36)
- tRNA determinants for transcription antitermination of the Bacillus subtilis tyrS gene. (2000) (35)
- Cloning and analysis of the Bacillus subtilis rpsD gene, encoding ribosomal protein S4 (1990) (35)
- The Staphylococcus aureus ileS gene, encoding isoleucyl-tRNA synthetase, is a member of the T-box family (1997) (31)
- tRNA regulation of gene expression: interactions of an mRNA 5'-UTR with a regulatory tRNA. (2006) (31)
- NMR structure and dynamics of the Specifier Loop domain from the Bacillus subtilis tyrS T box leader RNA (2010) (29)
- An Intergenic Stem-Loop Mutation in the Bacillus subtilis ccpA-motPS Operon Increases motPS Transcription and the MotPS Contribution to Motility (2006) (27)
- Identification of a Mutation in the Bacillus subtilis S-Adenosylmethionine Synthetase Gene That Results in Derepression of S-Box Gene Expression (2006) (27)
- Induction of the chloramphenicol acetyltransferase gene cat-86 through the action of the ribosomal antibiotic amicetin: involvement of a Bacillus subtilis ribosomal component in cat induction (1985) (26)
- The T-Box Riboswitch: tRNA as an Effector to Modulate Gene Regulation. (2018) (22)
- In Vivo and In Vitro Analyses of Regulation of the Pheromone-Responsive prgQ Promoter by the PrgX Pheromone Receptor Protein (2012) (22)
- Determinants of target prioritization and regulatory hierarchy for the bacterial small RNA SgrS (2017) (21)
- Mutations of the Escherichia coli lacUV5 promoter resulting in increased expression in Bacillus subtilis (1987) (20)
- Spectinomycin dependence in Bacillus subtilis (1979) (19)
- Molecular Genetics of Bacteria, 4th Edition (2019) (18)
- New tRNA contacts facilitate ligand binding in a Mycobacterium smegmatis T box riboswitch (2018) (17)
- Codon-Anticodon Recognition in the Bacillus subtilis glyQS T Box Riboswitch (2015) (17)
- Analysis of lysine recognition and specificity of the Bacillus subtilis L box riboswitch (2012) (17)
- The Bacillus subtilis tyrZ Gene Encodes a Highly Selective Tyrosyl-tRNA Synthetase and Is Regulated by a MarR Regulator and T Box Riboswitch (2015) (17)
- Ribosomes, Protein Synthesis Factors, and tRNA Synthetases (2002) (16)
- [37] Bacterial in Vitro protein-synthesizing systems (1983) (14)
- RNA-dependent RNA switches in bacteria. (2009) (13)
- New chloramphenicol resistance locus in Bacillus subtilis (1984) (13)
- Bacterial in vitro protein-synthesizing systems. (1983) (13)
- Genetic mapping of a mutation causing an alteration in Bacillus subtilis ribosomal protein S4 (2004) (13)
- Genetic analysis of a streptomycin-resistant oligosporogenous Bacillus subtilis mutant (1984) (12)
- Bacillus subtilis mutants with alterations in ribosomal protein S4 (1990) (8)
- MUTATIONS IN THE SPACER REGION OF A BACILLUS SUBTILIS PROMOTER (1988) (8)
- Non-Conserved Residues in Clostridium acetobutylicum tRNAAla Contribute to tRNA Tuning for Efficient Antitermination of the alaS T Box Riboswitch (2015) (8)
- A regulatory system hitherto found only in Gram‐positive bacteria in a Gram‐negative bacterium that grows only in co‐culture with a Bacillus strain (1999) (7)
- Inducible amber suppressor for Bacillus subtilis (1994) (7)
- Ribosomal Structure and Genetics (1993) (7)
- TherpsDGene,Encoding Ribosomal Protein S4,IsAutogenously Regulated inBacillus subtilis (1991) (6)
- Analysis of tRNA-directed transcription antitermination in the T box system in vivo. (2009) (6)
- Revertants of a streptomycin-resistant, oligosporogenous mutant ofBacillus subtilis (2004) (4)
- Transcriptional and translational S-box riboswitches differ in ligand-binding properties (2020) (3)
- Preface - riboswitches. (2014) (3)
- SOLUTION STRUCTURE OF B. SUBTILIS T BOX ANTITERMINATOR RNA (2003) (2)
- Classic Spotlight: Regulatory Function of Leader RNAs (2016) (1)
- Classic Spotlight: Bacterial Endospore Resistance, Structure, and Genetics (2016) (1)
- Dosage de transcription in vitro pour un systeme d'antiterminaison de boite t (2003) (0)
- Catherine L. Squires, 1941–2021: Scientist, Academic Leader, Mentor (2021) (0)
- Faculty Opinions recommendation of A new UAG-encoded residue in the structure of a methanogen methyltransferase. (2002) (0)
- Faculty Opinions recommendation of Yeast aspartyl-tRNA synthetase binds specifically its own mRNA. (2003) (0)
- Faculty Opinions recommendation of Coupled degradation of a small regulatory RNA and its mRNA targets in Escherichia coli. (2003) (0)
- Faculty Opinions recommendation of Pyrrolysine encoded by UAG in Archaea: charging of a UAG-decoding specialized tRNA. (2002) (0)
- Faculty Opinions recommendation of 5'-to-3' exoribonuclease activity in bacteria: role of RNase J1 in rRNA maturation and 5' stability of mRNA. (2007) (0)
- Classic Spotlight: Bacteria versus Phage—the Battle Rages! (2016) (0)
- Regulation at multiple levels: themes and variations. (2011) (0)
- Special Sections for the Inaugural Small Proteins, Big Questions Virtual Conference (2022) (0)
- Classic Spotlight: Selected Highlights from the First 100 Years of the Journal of Bacteriology (2017) (0)
- Cryo-EM-guided engineering of T-box-tRNA modules with enhanced selectivity and sensitivity in translational regulation (2023) (0)
- Faculty Opinions recommendation of The anti-trp RNA-binding attenuation protein (Anti-TRAP), AT, recognizes the tryptophan-activated RNA binding domain of the TRAP regulatory protein. (2002) (0)
- The Phage Meeting: Classical Venue, New Momentum (2006) (0)
- Regulation of bacterial gene expression by riboswitch RNAs (2011) (0)
- Control of Acetyl-Coenzyme A Synthetase (AcsA) Activity by Acetylation/Deacetylation without NAD+ Involvement in Bacillus subtilis (2006) (0)
- Riboswitches That Regulate Metabolism in Bacteria (2004) (0)
- Faculty Opinions recommendation of A Nascent Peptide Signal Responsive to Endogenous Levels of Polyamines Acts to Stimulate Regulatory Frameshifting on Antizyme mRNA. (2015) (0)
- Faculty Opinions recommendation of Regulation of 6S RNA by pRNA synthesis is required for efficient recovery from stationary phase in E. coli and B. subtilis. (2012) (0)
- 6.21 – Riboswitches (2010) (0)
- Specifier Domain of B. subtilis tyrS T box leader RNA (2010) (0)
- Folding interactions of an mRNA 5′‐UTR that regulates gene expression: Interaction with a regulatory tRNA (2006) (0)
- Faculty of 1000 evaluation for Bacterial persistence by RNA endonucleases. (2011) (0)
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