Toby Gibson
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Biochemist
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Toby Gibsonbiology Degrees
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Biochemistry
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Biology
Toby Gibson's Degrees
- PhD Biochemistry University of California, Berkeley
- Masters Chemistry Stanford University
- Bachelors Chemistry Stanford University
Why Is Toby Gibson Influential?
(Suggest an Edit or Addition)According to Wikipedia, Toby James Gibson is a group leader and biochemist at the European Molecular Biology Laboratory in Heidelberg known for his work on Clustal. According to Nature, Gibson's co-authored papers describing Clustal are among the top ten most highly cited scientific papers of all time.
Toby Gibson's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. (1994) (64052)
- The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. (1997) (39059)
- Clustal W and Clustal X version 2.0 (2007) (25261)
- Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega (2011) (11978)
- Multiple sequence alignment with the Clustal series of programs (2003) (5031)
- Multiple sequence alignment with Clustal X. (1998) (2656)
- Multiple Sequence Alignment Using ClustalW and ClustalX (2003) (2332)
- DNA sequence and expression of the B95-8 Epstein—Barr virus genome (1984) (1934)
- Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination. (1983) (1693)
- Using CLUSTAL for multiple sequence alignments. (1996) (1638)
- Protein disorder prediction: implications for structural proteomics. (2003) (1197)
- GlobPlot: exploring protein sequences for globularity and disorder (2003) (984)
- The PHD finger: implications for chromatin-mediated transcriptional regulation. (1995) (902)
- Phospho.ELM: a database of phosphorylation sites—update 2008 (2007) (679)
- ELM server: a new resource for investigating short functional sites in modular eukaryotic proteins (2003) (635)
- Ancient Protostome Origin of Chemosensory Ionotropic Glutamate Receptors and the Evolution of Insect Taste and Olfaction (2010) (611)
- The PH domain: a common piece in the structural patchwork of signalling proteins. (1993) (537)
- Attributes of short linear motifs. (2012) (479)
- The gene mutated in ataxia-ocular apraxia 1 encodes the new HIT/Zn-finger protein aprataxin (2001) (413)
- A million peptide motifs for the molecular biologist. (2014) (383)
- The SANT domain: a putative DNA-binding domain in the SWI-SNF and ADA complexes, the transcriptional co-repressor N-CoR and TFIIIB. (1996) (372)
- Phospho.ELM: A database of experimentally verified phosphorylation sites in eukaryotic proteins (2004) (347)
- How viruses hijack cell regulation. (2011) (345)
- Improved sensitivity of profile searches through the use of sequence weights and gap excision (1994) (328)
- ELM—the database of eukaryotic linear motifs (2011) (328)
- Short linear motifs: ubiquitous and functionally diverse protein interaction modules directing cell regulation. (2014) (326)
- Systematic Discovery of New Recognition Peptides Mediating Protein Interaction Networks (2005) (318)
- Phospho.ELM: a database of phosphorylation sites—update 2011 (2010) (310)
- Understanding eukaryotic linear motifs and their role in cell signaling and regulation. (2008) (308)
- PH domain: the first anniversary. (1994) (300)
- The eukaryotic linear motif resource ELM: 10 years and counting (2013) (298)
- ELM 2016—data update and new functionality of the eukaryotic linear motif resource (2015) (290)
- Three-Dimensional Structure and Stability of the KH Domain: Molecular Insights into the Fragile X Syndrome (1996) (281)
- Structure of the dsRNA binding domain of E. coli RNase III. (1995) (267)
- ELM: the status of the 2010 eukaryotic linear motif resource (2009) (261)
- SH3 — an abundant protein domain in search of a function (1992) (259)
- ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome (2007) (241)
- Malectin: a novel carbohydrate-binding protein of the endoplasmic reticulum and a candidate player in the early steps of protein N-glycosylation. (2008) (240)
- A regular pattern of two types of 100-residue motif in the sequence of titin (1990) (234)
- Base sequence discrimination by zinc-finger DNA-binding domains (1991) (226)
- The SAND domain structure defines a novel DNA-binding fold in transcriptional regulation (2001) (216)
- The KH domain occurs in a diverse set of RNA‐binding proteins that include the antiterminator NusA and is probably involved in binding to nucleic acid (1993) (201)
- Homology-based method for identification of protein repeats using statistical significance estimates. (2000) (201)
- A Proteome-wide Screen for Mammalian SxIP Motif-Containing Microtubule Plus-End Tracking Proteins (2012) (192)
- Evidence that nebulin is a protein‐ruler in muscle thin filaments (1991) (191)
- An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes (2015) (191)
- An organelle-specific protein landscape identifies novel diseases and molecular mechanisms (2016) (189)
- The transience of transient overexpression (2013) (182)
- The eukaryotic linear motif resource – 2018 update (2017) (173)
- A new method for isolating tyrosine kinase substrates used to identify Fish, an SH3 and PX domain‐containing protein, and Src substrate (1998) (173)
- The APECED polyglandular autoimmune syndrome protein, AIRE-1, contains the SAND domain and is probably a transcription factor. (1998) (169)
- Cell regulation: determined to signal discrete cooperation. (2009) (162)
- PairWise and SearchWise: finding the optimal alignment in a simultaneous comparison of a protein profile against all DNA translation frames. (1996) (160)
- Applying motif and profile searches. (1996) (158)
- Towards a structural understanding of Friedreich's ataxia: the solution structure of frataxin. (2000) (158)
- The ABBA motif binds APC/C activators and is shared by APC/C substrates and regulators. (2015) (154)
- Anopheles gambiae SRPN2 facilitates midgut invasion by the malaria parasite Plasmodium berghei (2005) (154)
- Dystrophin and utrophin: the missing links! (1995) (154)
- The phylogenetic distribution of frataxin indicates a role in iron-sulfur cluster protein assembly. (2001) (153)
- Friedreich's ataxia protein: phylogenetic evidence for mitochondrial dysfunction (1996) (150)
- Self-similarity in file systems (1998) (131)
- Nucleosome binding by the bromodomain and PHD finger of the transcriptional cofactor p300. (2004) (131)
- Motif switches: decision-making in cell regulation. (2012) (131)
- Genetic redundancy in vertebrates: polyploidy and persistence of genes encoding multidomain proteins. (1998) (128)
- The switches.ELM Resource: A Compendium of Conditional Regulatory Interaction Interfaces (2013) (121)
- A model for the tertiary structure of the 28 residue DNA-binding motif ('zinc finger') common to many eukaryotic transcriptional regulatory proteins. (1988) (118)
- The C terminus of fragile X mental retardation protein interacts with the multi-domain Ran-binding protein in the microtubule-organising centre. (2004) (114)
- Metabolic shifts in residual breast cancer drive tumor recurrence (2017) (113)
- Drift and conservation of differential exon usage across tissues in primate species (2013) (107)
- Dissecting FMR1, the protein responsible for fragile X syndrome, in its structural and functional domains. (1999) (96)
- Detection of dsRNA-binding domains in RNA helicase A and Drosophila maleless: implications for monomeric RNA helicases (1994) (93)
- The solution structure of the first KH domain of FMR1, the protein responsible for the fragile X syndrome (1997) (86)
- Degrons in cancer (2017) (82)
- CiliaCarta: An integrated and validated compendium of ciliary genes (2017) (82)
- A careful disorderliness in the proteome: Sites for interaction and targets for future therapies (2008) (81)
- Bacterial α2-macroglobulins: colonization factors acquired by horizontal gene transfer from the metazoan genome? (2004) (81)
- Lorist2, a cosmid with transcriptional terminators insulating vector genes from interference by promoters within the insert: effect on DNA yield and cloned insert frequency. (1987) (80)
- Homology between two EBV early genes and HSV ribonucleotide reductase and 38K genes. (1984) (79)
- Evidence in favour of ancient octaploidy in the vertebrate genome. (2000) (78)
- Proposed structure for the DNA-binding domain of the Myb oncoprotein based on model building and mutational analysis. (1991) (77)
- SLiMPrints: conservation-based discovery of functional motif fingerprints in intrinsically disordered protein regions (2012) (75)
- Proteome-wide analysis of human disease mutations in short linear motifs: neglected players in cancer? † (2014) (72)
- Solution structure of the basic region from the transcriptional activator GCN4. (1991) (71)
- Evidence for a protein domain superfamily shared by the cyclins, TFIIB and RB/p107. (1994) (71)
- Formin defines a large family of morphoregulatory genes and functions in establishment of the polarising region (1999) (71)
- Lorist6, a cosmid vector with BamHI, NotI, ScaI and HindIII cloning sites and altered neomycin phosphotransferase gene expression. (1987) (67)
- Linear motifs confer functional diversity onto splice variants (2012) (67)
- KH domains within the FMR1 sequence suggest that fragile X syndrome stems from a defect in RNA metabolism. (1993) (65)
- Dimerization and Protein Binding Specificity of the U2AF Homology Motif of the Splicing Factor Puf60* (2009) (65)
- DNA-binding domain ancestry (1989) (64)
- PDBe-KB: a community-driven resource for structural and functional annotations (2019) (63)
- Phosphorylation of S776 and 14-3-3 Binding Modulate Ataxin-1 Interaction with Splicing Factors (2009) (63)
- Solution structure of the DNA-binding domain of the yeast transcriptional activator protein GCN4. (1990) (60)
- CTCF-Mediated Chromatin Loops between Promoter and Gene Body Regulate Alternative Splicing across Individuals. (2017) (60)
- Linear motifs: lost in (pre)translation. (2012) (60)
- Asymmetric mRNA localization contributes to fidelity and sensitivity of spatially localized systems (2014) (58)
- The solution structure of a leucine-zipper motif peptide. (1991) (58)
- The identification of short linear motif-mediated interfaces within the human interactome (2012) (56)
- Experimental detection of short regulatory motifs in eukaryotic proteins: tips for good practice as well as for bad (2015) (55)
- A structure filter for the Eukaryotic Linear Motif Resource (2009) (52)
- PED in 2021: a major update of the protein ensemble database for intrinsically disordered proteins (2020) (51)
- A tree-based conservation scoring method for short linear motifs in multiple alignments of protein sequences (2008) (50)
- The phototrophic bacterium Rhodopseudomonas capsulata sp108 encodes an indigenous class A beta-lactamase. (1989) (46)
- Short linear motif candidates in the cell entry system used by SARS-CoV-2 and their potential therapeutic implications (2020) (45)
- Metabolic complexity in the RNA world and implications for the origin of protein synthesis (2005) (44)
- Discovery of candidate KEN-box motifs using Cell Cycle keyword enrichment combined with native disorder prediction and motif conservation (2008) (42)
- A Community Standard Format for the Representation of Protein Affinity Reagents* (2009) (42)
- RACK1 research – ships passing in the night? (2012) (41)
- Evidence for the Concerted Evolution between Short Linear Protein Motifs and Their Flanking Regions (2009) (41)
- The dimerization stability of the HLH-LZ transcription protein family is modulated by the leucine zippers: a CD and NMR study of TFEB and c-Myc. (1994) (38)
- Gene2EST: a BLAST2 server for searching expressed sequence tag (EST) databases with eukaryotic gene-sized queries. (2001) (37)
- A new protein linear motif benchmark for multiple sequence alignment software (2008) (35)
- iELM—a web server to explore short linear motif-mediated interactions (2012) (34)
- Elution Profile Analysis of SDS-induced Subcomplexes by Quantitative Mass Spectrometry* (2014) (33)
- The KH module has an αβ fold (1995) (33)
- KEPE—a motif frequently superimposed on sumoylation sites in metazoan chromatin proteins and transcription factors (2008) (28)
- Catalytic RNA and the origin of genetic systems. (1990) (28)
- The Eukaryotic Linear Motif resource: 2022 release (2021) (27)
- Exploring Short Linear Motifs Using the ELM Database and Tools (2017) (26)
- An Improved Long-Term File Usage Prediction Algorithm (1999) (26)
- An estimate of large‐scale sequencing accuracy (2000) (26)
- Short linear motif core and flanking regions modulate retinoblastoma protein binding affinity and specificity. (2018) (23)
- The BamHI F region of the B95-8 Epstein-Barr virus genome. (1985) (23)
- Mimicry of Short Linear Motifs by Bacterial Pathogens: A Drugging Opportunity. (2020) (23)
- Preparation of large numbers of plasmid DNA samples in microtiter plates by the alkaline lysis method. (1987) (23)
- Patterns and clusters within the PSM column in TiBS, 1992-2004. (2004) (20)
- NINL and DZANK1 Co-function in Vesicle Transport and Are Essential for Photoreceptor Development in Zebrafish (2015) (20)
- From sequence to structural analysis in protein phosphorylation motifs. (2011) (20)
- Long-Term file activity patterns in a UNIX workstation environment (1998) (20)
- Proposed structure for the DNA-binding domain of the helix-loop-helix family of eukaryotic gene regulatory proteins. (1993) (18)
- Letter to the Editor: Assignment of the 1H, 15N, and 13C resonances of the C-terminal domain of frataxin, the protein responsible for Friedreich ataxia (1999) (18)
- Long-term unix file system activity and the efficacy of automatic file migration (1998) (15)
- The evolution of titin and related giant muscle proteins (1994) (14)
- Capturing cooperative interactions with the PSI-MI format (2013) (11)
- An intrinsically disordered proteins community for ELIXIR (2019) (11)
- Corrigendum: ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome (2007) (11)
- Low probability of dystrophin and utrophin coiled coil regions forming dimers. (1996) (11)
- Transcription of Alu DNA elements in blood cells of sporadic Creutzfeldt-Jakob disease (sCJD) (2010) (10)
- Intermolecular base stacking mediates RNA-RNA interaction in a crystal structure of the RNA chaperone Hfq (2017) (10)
- EpiC: an open resource for exploring epitopes to aid antibody-based experiments. (2010) (10)
- Coding content and expression of the EBV B95-8 genome in the region from base 62,248 to base 82,920. (1986) (9)
- Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors (2019) (9)
- Protruding domain of tomato bushy stunt virus coat protein is a hitherto unrecognized class of jellyroll conformation. (1990) (8)
- Object-oriented parsing of biological databases with Python (2000) (8)
- BLAST2SRS, a web server for flexible retrieval of related protein sequences in the SWISS-PROT and SPTrEMBL databases (2003) (7)
- Examination of band dispersion during size-selective capillary electrophoresis separations of DNA fragments. (1997) (7)
- The KH module has an alpha beta fold. (1995) (7)
- The Gene Ontology of eukaryotic cilia and flagella (2017) (5)
- Non-muscle and smooth muscle myosin light chain kinases: no end in sight. (1993) (5)
- The articles.ELM resource: simplifying access to protein linear motif literature by annotation, text-mining and classification (2020) (4)
- Possible Editing of Alu Transcripts in Blood Cells of Sporadic Creutzfeldt–Jakob Disease (sCJD) (2011) (3)
- Rop/helix-loop-helix similarity. (1991) (3)
- Structural basis for tunable affinity and specificity of LxCxE-dependent protein interactions with the retinoblastoma protein family (2022) (3)
- Experimental detection of short regulatory motifs in eukaryotic proteins: tips for good practice as well as for bad (2015) (3)
- EpiC: A Resource for Integrating Information and Analyses to Enable Selection of Epitopes for Antibody Based Experiments (2009) (3)
- Divergent evolution of a protein-protein interaction revealed through ancestral sequence reconstruction and resurrection (2020) (3)
- Prion infected rhesus monkeys to study differential transcription of Alu DNA elements and editing of Alu transcripts in neuronal cells and blood cells (2012) (3)
- The Eukaryotic Linear Motif Resource (ELM): Regulatory Sites in Proteins (2009) (3)
- Control of mitotic chromosome condensation by the fission yeast transcription factor Zas1 (2018) (3)
- RuNAway Disease: A two cycle model for transmissible spongiform encephalopathies (TSEs) wherein SINE proliferation drives PrP overproduction (2001) (3)
- How to Annotate and Submit a Short Linear Motif to the Eukaryotic Linear Motif Resource. (2020) (2)
- Proteomics' framework for success? (2007) (2)
- A Tool to Build Up-To-Date Gene Annotations for Affymetrix Microarrays (2017) (2)
- Long-term File System Activity and Inter-reference Periods (1998) (2)
- Divergent Evolution of a Protein–Protein Interaction Revealed through Ancestral Sequence Reconstruction and Resurrection (2020) (2)
- Examination of cyanine intercalation dyes for rapid and sensitive detection of DNA fragments by capillary electrophoresis. (1998) (2)
- Assignment of α-Helices in Multiply Aligned Protein Sequences — Applications to DNA Binding Motifs (1992) (2)
- A Comparative Analysis to Study Editing of Small Noncoding BC200- and Alu Transcripts in Brain of Prion-Inoculated Rhesus Monkeys (M. Mulatta) (2012) (2)
- Computational Analysis of Modular Protein Architectures (2008) (2)
- The Case For Personal Computers As Workstations (1996) (2)
- Evaluation of the suitability of a Zipfian gap model for pairwise sequence alignment (2011) (1)
- Sexist ads (1986) (1)
- Conserved SQ and QS motifs in bacterial effectors suggest pathogen interplay with the ATM kinase family during infection (2018) (1)
- PCARE requires coiled coil, RP62 kinase-binding and EVH1 domain-binding motifs for ciliary expansion (2022) (1)
- An intrinsically disordered proteins community for ELIXIR [version 1; peer review: 2 approved] (2020) (1)
- Comprehensive gene ontology annotation of ciliary genes in the laboratory mouse (2017) (1)
- Hunting for Cis-Regulatory Elements in Proteins. (2016) (1)
- THE SOLUTION STRUCTURE OF THE THE C-TERMINAL DOMAIN OF FRATAXIN, THE PROTEIN RESPONSIBLE FOR FRIEDREICH ATAXIA (1999) (0)
- Solution structure of the human Sp100b SAND domain by heteronuclear NMR. (2001) (0)
- Towards the gene ontology of the eukaryotic cilia and flagella (2016) (0)
- Intermolecular base stacking mediates RNA-RNA interaction in a crystal structure of the RNA chaperone Hfq (2017) (0)
- Assignment of the 1H, 15N, and 13C Resonances of the C-terminal Domain of Frataxin, the Protein Involved in Friedreich Ataxia. (2000) (0)
- NMR STUDY OF VIGILIN, REPEAT 6, 40 STRUCTURES (1996) (0)
- Title Fast , scalable generation of high-quality protein multiplesequence alignments using Clustal Omega (2017) (0)
- Decision letter: Quantitative mapping of protein-peptide affinity landscapes using spectrally encoded beads (2018) (0)
- Brief Communication Structure and Expression of the Epstein-Barr Virus Genome (1985) (0)
- The Roles of Short Linear Motifs in Human Diseases (2014) (0)
- LeishMANIAdb: a comparative resource for Leishmania proteins (2023) (0)
- Capillary electrophoresis investigations of pET3aPAI-1 DNA involving optimized restriction digestion, laser-induced fluorescence detection, and micropreparative separation (1998) (0)
- KH1 FROM THE FRAGILE X PROTEIN FMR1, NMR, 18 STRUCTURES (1998) (0)
- NMR STUDY OF VIGILIN, REPEAT 6, MINIMIZED AVERAGE STRUCTURE (1996) (0)
- A systems biology approach towards the prediction of ciliopathy mechanisms (2015) (0)
- Explorer An organelle-specific protein landscape identifies novel diseases and molecular mechanisms (2016) (0)
- Abstracts of the XVIII European Conference on Muscle and Motility (1990) (0)
- Pipeline for transferring annotations between proteins beyond globular domains (2022) (0)
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What Schools Are Affiliated With Toby Gibson?
Toby Gibson is affiliated with the following schools:
