Todd M. Allen | Academic Influence

Todd M. Allen's AcademicInfluence.com Rankings

Todd M. Allen

Computer Science

#11166

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#11798

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Machine Learning

#5104

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#5167

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Artificial Intelligence

#5507

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#5584

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Database

#8197

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#8550

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computer-science Degrees

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Computer Science

Todd M. Allen's Degrees

PhD Computer Science Stanford University
Masters Computer Science University of California, Berkeley
Bachelors Computer Science University of California, Berkeley

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Why Is Todd M. Allen Influential?

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According to Wikipedia, Todd Mackenzie Allen is a Canadian-born immunologist and virologist at the Ragon Institute of MGH, MIT and Harvard, and a Professor of Medicine at Harvard University. He is a specialist in HIV vaccine design and the sequence evolution and diversity of HIV and hepatitis C virus . More recently, his work is focused on developing novel immunotherapeutic approaches towards a functional cure of HIV, including chimeric antigen receptor T cell immunotherapy and gene editing approaches capable of protecting against HIV infection.

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Todd M. Allen's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation (2010) (1129)
Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA (2004) (858)
Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia (2000) (767)
The epigenetic landscape of T cell exhaustion (2016) (603)
Adaptation of HIV-1 to human leukocyte antigen class I (2009) (475)
Differential natural killer cell–mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes (2007) (464)
Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9. (2014) (415)
Acute phase cytotoxic T lymphocyte escape is a hallmark of simian immunodeficiency virus infection (2002) (413)
Virus-specific cytotoxic T-lymphocyte responses select for amino-acid variation in simian immunodeficiency virus Env and Nef (1999) (412)
Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection (2003) (392)
Selective Escape from CD8+ T-Cell Responses Represents a Major Driving Force of Human Immunodeficiency Virus Type 1 (HIV-1) Sequence Diversity and Reveals Constraints on HIV-1 Evolution (2005) (379)
Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment‐naïve patients (2008) (371)
Whole Genome Deep Sequencing of HIV-1 Reveals the Impact of Early Minor Variants Upon Immune Recognition During Acute Infection (2012) (350)
Escape from the Dominant HLA-B27-Restricted Cytotoxic T-Lymphocyte Response in Gag Is Associated with a Dramatic Reduction in Human Immunodeficiency Virus Type 1 Replication (2007) (347)
Effective Induction of Simian Immunodeficiency Virus-Specific Cytotoxic T Lymphocytes in Macaques by Using a Multiepitope Gene and DNA Prime-Modified Vaccinia Virus Ankara Boost Vaccination Regimen (1999) (346)
HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1 (2006) (345)
HIV-1 adaptation to NK cell mediated immune pressure (2011) (337)
CD8 Epitope Escape and Reversion in Acute HCV Infection (2004) (333)
High resolution analysis of cellular immune responses in resolved and persistent hepatitis C virus infection. (2004) (331)
HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus (2002) (330)
Analysis of Gag-specific Cytotoxic T Lymphocytes in Simian Immunodeficiency Virus–infected Rhesus Monkeys by Cell Staining with a Tetrameric Major Histocompatibility Complex Class I–Peptide Complex (1998) (323)
Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity. (2010) (320)
Relative Dominance of Gag p24-Specific Cytotoxic T Lymphocytes Is Associated with Human Immunodeficiency Virus Control (2006) (315)
Escape and Compensation from Early HLA-B57-Mediated Cytotoxic T-Lymphocyte Pressure on Human Immunodeficiency Virus Type 1 Gag Alter Capsid Interactions with Cyclophilin A (2007) (297)
Effects of thymic selection of the T cell repertoire on HLA-class I associated control of HIV infection (2010) (296)
Induction of AIDS Virus-Specific CTL Activity in Fresh, Unstimulated Peripheral Blood Lymphocytes from Rhesus Macaques Vaccinated with a DNA Prime/Modified Vaccinia Virus Ankara Boost Regimen1 (2000) (276)
Mucosal AIDS vaccine reduces disease and viral load in gut reservoir and blood after mucosal infection of macaques (2001) (273)
Selection, Transmission, and Reversion of an Antigen-Processing Cytotoxic T-Lymphocyte Escape Mutation in Human Immunodeficiency Virus Type 1 Infection (2004) (270)
Antigen Load and Viral Sequence Diversification Determine the Functional Profile of HIV-1–Specific CD8+ T Cells (2008) (266)
Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes (2006) (256)
HLA-B57/B*5801 Human Immunodeficiency Virus Type 1 Elite Controllers Select for Rare Gag Variants Associated with Reduced Viral Replication Capacity and Strong Cytotoxic T-Lymphotye Recognition (2008) (244)
Characterization of the peptide binding motif of a rhesus MHC class I molecule (Mamu-A*01) that binds an immunodominant CTL epitope from simian immunodeficiency virus. (1998) (232)
TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection (2012) (230)
Selection bias at the heterosexual HIV-1 transmission bottleneck (2013) (225)
Inhibition of HIV transmission in human cervicovaginal explants and humanized mice using CD4 aptamer-siRNA chimeras. (2011) (223)
Expression of the Major Histocompatibility Complex Class I Molecule Mamu-A*01 Is Associated with Control of Simian Immunodeficiency Virus SIVmac239 Replication (2003) (214)
High Level of PD-1 Expression on Hepatitis C Virus (HCV)-Specific CD8+ and CD4+ T Cells during Acute HCV Infection, Irrespective of Clinical Outcome (2007) (213)
Broadly directed virus-specific CD4+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence (2012) (210)
Marked Epitope- and Allele-Specific Differences in Rates of Mutation in Human Immunodeficiency Type 1 (HIV-1) Gag, Pol, and Nef Cytotoxic T-Lymphocyte Epitopes in Acute/Early HIV-1 Infection (2008) (202)
Coordinate linkage of HIV evolution reveals regions of immunological vulnerability (2011) (199)
Broad Repertoire of the CD4+ Th Cell Response in Spontaneously Controlled Hepatitis C Virus Infection Includes Dominant and Highly Promiscuous Epitopes1 (2005) (191)
Major Histocompatibility Complex Class I Alleles Associated with Slow Simian Immunodeficiency Virus Disease Progression Bind Epitopes Recognized by Dominant Acute-Phase Cytotoxic-T-Lymphocyte Responses (2003) (189)
Vaccine-induced CD8+ T cells control AIDS virus replication (2012) (177)
Rapid Reversion of Sequence Polymorphisms Dominates Early Human Immunodeficiency Virus Type 1 Evolution (2006) (175)
CD8+ Lymphocytes from Simian Immunodeficiency Virus-Infected Rhesus Macaques Recognize 14 Different Epitopes Bound by the Major Histocompatibility Complex Class I Molecule Mamu-A*01: Implications for Vaccine Design and Testing (2001) (171)
De Novo Generation of Escape Variant-Specific CD8+ T-Cell Responses following Cytotoxic T-Lymphocyte Escape in Chronic Human Immunodeficiency Virus Type 1 Infection (2005) (161)
Persistent Recognition of Autologous Virus by High-Avidity CD8 T Cells in Chronic, Progressive Human Immunodeficiency Virus Type 1 Infection (2004) (159)
Structural and Functional Constraints Limit Options for Cytotoxic T-Lymphocyte Escape in the Immunodominant HLA-B27-Restricted Epitope in Human Immunodeficiency Virus Type 1 Capsid (2008) (159)
A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control (2013) (158)
Definition of the viral targets of protective HIV-1-specific T cell responses (2011) (157)
HLA-B57/B*5801 Human Immunodeficiency Virus Type 1 Elite Controllers Select for Rare Gag Variants Associated with Reduced Viral Replication Capacity and Strong Cytotoxic T-Lymphocyte Recognition (2009) (152)
Dominance of CD8 Responses Specific for Epitopes Bound by a Single Major Histocompatibility Complex Class I Molecule during the Acute Phase of Viral Infection (2002) (151)
Spontaneous control of HCV is associated with expression of HLA-B 57 and preservation of targeted epitopes. (2011) (150)
Enhanced Detection of Human Immunodeficiency Virus Type 1-Specific T-Cell Responses to Highly Variable Regions by Using Peptides Based on Autologous Virus Sequences (2003) (147)
Protective HLA Class I Alleles That Restrict Acute-Phase CD8+ T-Cell Responses Are Associated with Viral Escape Mutations Located in Highly Conserved Regions of Human Immunodeficiency Virus Type 1 (2008) (141)
Genetic Characterization of Human Immunodeficiency Virus Type 1 in Elite Controllers: Lack of Gross Genetic Defects or Common Amino Acid Changes (2008) (140)
Early Selection in Gag by Protective HLA Alleles Contributes to Reduced HIV-1 Replication Capacity That May Be Largely Compensated for in Chronic Infection (2010) (140)
Cutting Edge: Prolonged Exposure to HIV Reinforces a Poised Epigenetic Program for PD-1 Expression in Virus-Specific CD8 T Cells (2013) (138)
HLA-Associated Alterations in Replication Capacity of Chimeric NL4-3 Viruses Carrying gag-protease from Elite Controllers of Human Immunodeficiency Virus Type 1 (2008) (134)
Virological and immunological determinants of intrahepatic virus‐specific CD8+ T‐cell failure in chronic hepatitis C virus infection (2008) (134)
Selective Depletion of High-Avidity Human Immunodeficiency Virus Type 1 (HIV-1)-Specific CD8+ T Cells after Early HIV-1 Infection (2007) (131)
HIV-1 specific CD8+ T cells with an effector phenotype and control of viral replication (2004) (130)
HIV-1 Nef is preferentially recognized by CD8 T cells in primary HIV-1 infection despite a relatively high degree of genetic diversity (2004) (128)
Immune-driven recombination and loss of control after HIV superinfection (2008) (125)
Highly Sensitive and Specific Detection of Rare Variants in Mixed Viral Populations from Massively Parallel Sequence Data (2012) (124)
HIV-1–specific cytotoxicity is preferentially mediated by a subset of CD8+ T cells producing both interferon-γ and tumor necrosis factor–α (2004) (122)
Tat-Vaccinated Macaques Do Not Control Simian Immunodeficiency Virus SIVmac239 Replication (2002) (120)
HIV-1 Viral Escape in Infancy Followed by Emergence of a Variant-Specific CTL Response1 (2005) (117)
Full-Breadth Analysis of CD8+ T-Cell Responses in Acute Hepatitis C Virus Infection and Early Therapy (2005) (114)
Viral Sequence Evolution in Acute Hepatitis C Virus Infection (2007) (107)
Human leukocyte antigen–associated sequence polymorphisms in hepatitis C virus reveal reproducible immune responses and constraints on viral evolution (2007) (106)
A viral CTL escape mutation leading to immunoglobulin-like transcript 4–mediated functional inhibition of myelomonocytic cells (2007) (105)
Humanized immune system mouse models: progress, challenges and opportunities (2019) (104)
Constraints on HIV-1 evolution and immunodominance revealed in monozygotic adult twins infected with the same virus (2006) (102)
Escape in One of Two Cytotoxic T-Lymphocyte Epitopes Bound by a High-Frequency Major Histocompatibility Complex Class I Molecule, Mamu-A*02: a Paradigm for Virus Evolution and Persistence? (2002) (102)
Differential Neutralization of Human Immunodeficiency Virus (HIV) Replication in Autologous CD4 T Cells by HIV-Specific Cytotoxic T Lymphocytes (2009) (101)
Functional Impairment of Simian Immunodeficiency Virus-Specific CD8+ T Cells during the Chronic Phase of Infection (2001) (99)
Comparison of vaccine strategies using recombinant env-gag-pol MVA with or without an oligomeric Env protein boost in the SHIV rhesus macaque model. (2002) (98)
Impaired Hepatitis C Virus-Specific T Cell Responses and Recurrent Hepatitis C Virus in HIV Coinfection (2006) (97)
Hitting HIV where it hurts: an alternative approach to HIV vaccine design. (2006) (96)
Viral evolution and escape during acute HIV-1 infection. (2010) (95)
Mutually Exclusive T-Cell Receptor Induction and Differential Susceptibility to Human Immunodeficiency Virus Type 1 Mutational Escape Associated with a Two-Amino-Acid Difference between HLA Class I Subtypes (2006) (94)
Immunological and virological impact of highly active antiretroviral therapy initiated during acute HIV-1 infection. (2006) (91)
Impact of Pre-adapted HIV Transmission (2016) (90)
BLT-humanized C57BL/6 Rag2-/-γc-/-CD47-/- mice are resistant to GVHD and develop B- and T-cell immunity to HIV infection. (2013) (88)
Hepatitis C Virus Reinfection and Spontaneous Clearance of Reinfection--the InC3 Study. (2015) (88)
PD-1 Blockade in Chronically HIV-1-Infected Humanized Mice Suppresses Viral Loads (2013) (86)
Differences in the Selection Bottleneck between Modes of Sexual Transmission Influence the Genetic Composition of the HIV-1 Founder Virus (2016) (85)
HLA-B63 Presents HLA-B57/B58-Restricted Cytotoxic T-Lymphocyte Epitopes and Is Associated with Low Human Immunodeficiency Virus Load (2005) (83)
Structural topology defines protective CD8+ T cell epitopes in the HIV proteome (2019) (81)
Definition of Five New Simian Immunodeficiency Virus Cytotoxic T-Lymphocyte Epitopes and Their Restricting Major Histocompatibility Complex Class I Molecules: Evidence for an Influence on Disease Progression (2000) (81)
Complete viral RNA genome sequencing of ultra-low copy samples by sequence-independent amplification (2012) (80)
Use of a novel GFP reporter cell line to examine replication capacity of CXCR4- and CCR5-tropic HIV-1 by flow cytometry. (2006) (80)
Impairment of Gag-Specific CD8+ T-Cell Function in Mucosal and Systemic Compartments of Simian Immunodeficiency Virus mac251- and Simian-Human Immunodeficiency Virus KU2-Infected Macaques (2001) (79)
Hepatitis C Virus (HCV) Sequence Variation Induces an HCV-Specific T-Cell Phenotype Analogous to Spontaneous Resolution (2009) (79)
HIV-1-specific cytotoxicity is preferentially mediated by a subset of CD8(+) T cells producing both interferon-gamma and tumor necrosis factor-alpha. (2004) (77)
Capturing sequence diversity in metagenomes with comprehensive and scalable probe design (2019) (76)
Epigenetic scars of CD8+ T cell exhaustion persist after cure of chronic infection in humans (2021) (75)
BLT humanized mice as a small animal model of HIV infection. (2015) (74)
Reduced Replication Capacity of NL4-3 Recombinant Viruses Encoding Reverse Transcriptase–Integrase Sequences From HIV-1 Elite Controllers (2011) (73)
Transmission and Long-Term Stability of Compensated CD8 Escape Mutations (2008) (69)
Fluctuations of functionally distinct CD8+ T-cell clonotypes demonstrate flexibility of the HIV-specific TCR repertoire. (2006) (66)
Differential regulation of toll-like receptor pathways in acute and chronic HIV-1 infection (2012) (64)
Induction of Mucosal Homing Virus-Specific CD8+ T Lymphocytes by Attenuated Simian Immunodeficiency Virus (2000) (63)
Protective effect of human leukocyte antigen B27 in hepatitis C virus infection requires the presence of a genotype‐specific immunodominant CD8+ T‐cell epitope (2010) (61)
Effects of Cytotoxic T Lymphocytes (CTL) Directed against a Single Simian Immunodeficiency Virus (SIV) Gag CTL Epitope on the Course of SIVmac239 Infection (2002) (61)
Increased Cytotoxic T-Lymphocyte Epitope Variant Cross-Recognition and Functional Avidity Are Associated with Hepatitis C Virus Clearance (2008) (59)
Limited Sequence Evolution within Persistently Targeted CD8 Epitopes in Chronic Human Immunodeficiency Virus Type 1 Infection (2005) (58)
Antigen recognition-triggered drug delivery mediated by nanocapsule-functionalized cytotoxic T-cells. (2017) (54)
Human leukocyte antigen B27 selects for rare escape mutations that significantly impair hepatitis C virus replication and require compensatory mutations (2011) (51)
Understanding cytotoxic T‐lymphocyte escape during simian immunodeficiency virus infection (2001) (50)
Crippling HIV one mutation at a time (2008) (50)
HLA Footprints on Human Immunodeficiency Virus Type 1 Are Associated with Interclade Polymorphisms and Intraclade Phylogenetic Clustering (2009) (49)
Frequent and Variable Cytotoxic-T-Lymphocyte Escape-Associated Fitness Costs in the Human Immunodeficiency Virus Type 1 Subtype B Gag Proteins (2013) (49)
Antiviral CD8+ T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion (2016) (49)
Maternal Transmission of Human Immunodeficiency Virus Escape Mutations Subverts HLA-B57 Immunodominance but Facilitates Viral Control in the Haploidentical Infant (2009) (47)
The Majority of Currently Circulating Human Immunodeficiency Virus Type 1 Clade B Viruses Fail To Prime Cytotoxic T-Lymphocyte Responses against an Otherwise Immunodominant HLA-A2-Restricted Epitope: Implications for Vaccine Design (2005) (46)
Contribution of immunological and virological factors to extremely severe primary HIV type 1 infection. (2009) (45)
Early Transcriptional Divergence Marks Virus‐Specific Primary Human CD8+ T Cells in Chronic versus Acute Infection (2017) (45)
Erratum: HIV-1 superinfection despite broad CD8 + T-cell responses containing replication of the primary virus (Nature (2002) 420 (434-439)) (2003) (43)
HIV-1 superinfection. (2003) (42)
DNA immunization in combination with effective antiretroviral drug therapy controls viral rebound and prevents simian AIDS after treatment is discontinued. (2006) (41)
Whole genome pyrosequencing of rare hepatitis C virus genotypes enhances subtype classification and identification of naturally occurring drug resistance variants. (2013) (40)
Fine specificity and cross-clade reactivity of HIV type 1 Gag-specific CD4+ T cells. (2004) (38)
Tumor necrosis factor α is associated with viral control and early disease progression in patients with HIV type 1 infection. (2014) (38)
Dual CD4-based CAR T cells with distinct costimulatory domains mitigate HIV pathogenesis in vivo (2020) (37)
Increased detection of HIV-specific T cell responses by combination of central sequences with comparable immunogenicity (2008) (37)
Increased Sequence Diversity Coverage Improves Detection of HIV-Specific T Cell Responses1 (2007) (37)
Gorillas with Spondyloarthropathies Express an MHC Class I Molecule with Only Limited Sequence Similarity to HLA-B27 that Binds Peptides with Arginine at P21 (2001) (36)
A high incidence of Shigella-induced arthritis in a primate species: major histocompatibility complex class I molecules associated with resistance and susceptiblity, and their relationship to HLA-B27 (2000) (36)
Characterization of full‐length hepatitis C virus genotype 4 sequences (2007) (36)
Increased frequency and function of KIR2DL1–3+ NK cells in primary HIV‐1 infection are determined by HLA‐C group haplotypes (2014) (35)
Protective Efficacy of Broadly Neutralizing Antibodies with Incomplete Neutralization Activity against Simian-Human Immunodeficiency Virus in Rhesus Monkeys (2017) (34)
Protection of Humanized Mice From Repeated Intravaginal HIV Challenge by Passive Immunization: A Model for Studying the Efficacy of Neutralizing Antibodies In Vivo. (2016) (33)
Differentiation of exhausted CD8 T cells after termination of chronic antigen stimulation stops short of achieving functional T cell memory (2021) (32)
Frequent and Strong Antibody-Mediated Natural Killer Cell Activation in Response to HIV-1 Env in Individuals with Chronic HIV-1 Infection (2012) (30)
Simian Immunodeficiency Virus That Binds an Immunodominant CTL Epitope a Rhesus MHC Class I Molecule ( Mamu-A * 01 ) Characterization of the Peptide Binding Motif of (1998) (29)
Immunologic evidence for lack of heterologous protection following resolution of HCV in patients with non-genotype 1 infection. (2007) (29)
HLA-B*27 subtype specificity determines targeting and viral evolution of a hepatitis C virus-specific CD8+ T cell epitope. (2014) (29)
High resolution sequencing of hepatitis C virus reveals limited intra-hepatic compartmentalization in end-stage liver disease (2017) (28)
Compensatory Mutations Restore the Replication Defects Caused by Cytotoxic T Lymphocyte Escape Mutations in Hepatitis C Virus Polymerase (2011) (28)
Vaccine-Induced Simian Immunodeficiency Virus-Specific CD8+ T-Cell Responses Focused on a Single Nef Epitope Select for Escape Variants Shortly after Infection (2015) (26)
How a single patient influenced HIV research--15-year follow-up. (2014) (26)
Deep sequencing of hepatitis C virus reveals genetic compartmentalization in cerebrospinal fluid from cognitively impaired patients (2016) (25)
Effect of scavenger receptor class B type I antagonist ITX5061 in patients with hepatitis C virus infection undergoing liver transplantation (2016) (25)
Immunodominance of a single CTL epitope in a primate species with limited MHC class I polymorphism. (1997) (25)
Enhanced immune activation linked to endotoxemia in HIV-1 seronegative MSM (2014) (24)
Escape from a Dominant HLA-B*15-Restricted CD8+ T Cell Response against Hepatitis C Virus Requires Compensatory Mutations outside the Epitope (2011) (24)
Increased Breadth and Depth of Cytotoxic T Lymphocytes Responses against HIV-1-B Nef by Inclusion of Epitope Variant Sequences (2011) (24)
STI and beyond: the prospects of boosting anti-HIV immune responses. (2002) (24)
Trace amounts of sporadically reappearing HCV RNA can cause infection. (2014) (24)
Temporal dynamics of a predominant protease inhibitor-resistance mutation in a treatment-naive, hepatitis C virus-infected individual. (2009) (24)
Analysis of the TCR β Variable Gene Repertoire in Chimpanzees: Identification of Functional Homologs to Human Pseudogenes1 (2003) (23)
Hepatitis C Virus Immune Escape via Exploitation of a Hole in the T Cell Repertoire1 (2008) (22)
Cytotoxic T-lymphocyte escape monitoring in simian immunodeficiency virus vaccine challenge studies. (2002) (21)
Immunogenicity of hybrid DNA vaccines expressing hepatitis B core particles carrying human and simian immunodeficiency virus epitopes in mice and rhesus macaques. (2007) (21)
Prolonged Exposure to HIV Reinforces a Poised Epigenetic Program for PD-1 Expression in Virus-Specific CD8 T Cells (20)
HIV-specific CD8⁺ T-cell immunity in humanized bone marrow-liver-thymus mice. (2013) (19)
Design, Expression, and Processing of Epitomized Hepatitis C Virus-Encoded CTL Epitopes1 (2008) (17)
Efficient Ablation of Genes in Human Hematopoietic Stem and Effector Cells using CRISPR / Cas 9 Graphical (2014) (17)
HIV-1 Balances the Fitness Costs and Benefits of Disrupting the Host Cell Actin Cytoskeleton Early after Mucosal Transmission. (2019) (16)
Early immune adaptation in HIV-1 revealed by population-level approaches (2014) (16)
Differences in the expressed HLA class I alleles effect the differential clustering of HIV type 1-specific T cell responses in infected Chinese and caucasians. (2004) (16)
Immunization of BLT Humanized Mice Redirects T Cell Responses to Gag and Reduces Acute HIV-1 Viremia (2019) (15)
Naturally Occurring Subclinical Endotoxemia in Humans Alters Adaptive and Innate Immune Functions through Reduced MAPK and Increased STAT1 Phosphorylation (2016) (15)
HIV Antibody Fc N-Linked Glycosylation Is Associated with Viral Rebound. (2020) (15)
Recent advances in humanized mice: accelerating the development of an HIV vaccine. (2013) (15)
Temporal effect of HLA-B*57 on viral control during primary HIV-1 infection (2013) (15)
The T-cell receptor β chain-encoding gene repertoire of a New World primate species, the cotton-top tamarin (1996) (14)
Vaccination with CTL epitopes that escape: an alternative approach to HIV vaccine development? (2001) (14)
Distinct Escape Pathway by Hepatitis C Virus Genotype 1a from a Dominant CD8+ T Cell Response by Selection of Altered Epitope Processing (2015) (14)
Loss of HIV-1-specific T-cell responses associated with very rapid HIV-1 disease progression. (2007) (13)
PriSM: a primer selection and matching tool for amplification and sequencing of viral genomes (2011) (13)
A Novel Immunodominant CD8+ T Cell Response Restricted by a Common HLA-C Allele Targets a Conserved Region of Gag HIV-1 Clade CRF01_AE Infected Thais (2011) (13)
Early type I Interferon response induces upregulation of human β-defensin 1 during acute HIV-1 infection (2017) (13)
A set of reference sequences for the hepatitis C genotypes 4d, 4f, and 4k covering the full open reading frame (2008) (12)
Innate immune reconstitution with suppression of HIV-1. (2016) (12)
Ceestatin, a novel small molecule inhibitor of hepatitis C virus replication, inhibits 3-hydroxy-3-methylglutaryl-coenzyme A synthase. (2011) (12)
Disease progression despite protective HLA expression in an HIV-infected transmission pair (2015) (11)
Rare Control of SIVmac239 Infection in a Vaccinated Rhesus Macaque. (2017) (11)
Rapid HIV disease progression following superinfection in an HLA-B*27:05/B*57:01-positive transmission recipient (2018) (10)
Dengue Virus Evades AAV-Mediated Neutralizing Antibody Prophylaxis in Rhesus Monkeys. (2017) (10)
Phenotypic analysis of NS5A variant from liver transplant patient with increased cyclosporine susceptibility. (2013) (10)
Functional impairment of HIV-specific CD8+ T cells precedes aborted spontaneous control of viremia. (2021) (9)
Mamu-B*17+ Rhesus Macaques Vaccinated with env, vif, and nef Manifest Early Control of SIVmac239 Replication (2018) (9)
Differentiation of exhausted CD8+ T cells after termination of chronic antigen stimulation stops short of achieving functional T cell memory (2021) (8)
Review article: HCV ? STAT-C era of therapy (2010) (8)
Capturing diverse microbial sequence with comprehensive and scalable probe design (2018) (8)
Metagenomic Sequencing of HIV-1 in the Blood and Female Genital Tract Reveals Little Quasispecies Diversity during Acute Infection (2018) (8)
New insights into evaluating effective T-cell responses to HIV (2001) (7)
Viral evolution and escape during primary human immunodeficiency virus-1 infection: implications for vaccine design (2008) (7)
Use of Dried Blood Spots to Elucidate Full-Length Transmitted/Founder HIV-1 Genomes (2016) (7)
Enhanced immune activation linked to endotoxemia in HIV-1 seronegative men who have sex with men (2014) (6)
Macaques Immunodeficiency Virus KU 2-Infected Virus mac 251-and Simian-Human Compartments of Simian Immunodeficiency Function in Mucosal and Systemic T-Cell + Impairment of Gag-Specific CD 8 (2001) (6)
addendum: HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus (2003) (5)
Poly I:C and STING agonist‐primed DC increase lymphoid tissue polyfunctional HIV‐1‐specific CD8+ T cells and limit CD4+ T‐cell loss in BLT mice (2021) (5)
Role of HCV Viremia in Corroborated HCV Transmission Events Within Young Adult Injecting Partnerships (2019) (5)
Epidemiologically linked transmission of HIV-1 illustrates the impact of host genetics on virological outcome (2009) (4)
Lower Broadly Neutralizing Antibody Responses in Female Versus Male HIV-1 Infected Injecting Drug Users (2019) (4)
High Level of PD-1 Expression on Hepatitis C Virus (HCV)-Specific CD8+ and CD4+ T Cells during Acute HCV Infection, Irrespective of Clinical Outcome (2011) (4)
replication of the primary virus (2002) (4)
Innate Immune Reconstitution in Humanized Bone Marrow-Liver-Thymus (HuBLT) Mice Governs Adaptive Cellular Immune Function and Responses to HIV-1 Infection (2021) (4)
Sensitive population profiling and genome assembly of HIV and Flaviviruses using ultra-deep sequencing technologies (2010) (3)
Gp41-targeted antibodies restore infectivity of a fusion-deficient HIV-1 envelope glycoprotein (2020) (2)
Impact of NK cells on control of HIV infection in humanized BLT mice (P6207) (2013) (2)
P222 DISTINCT ESCAPE PATHWAY BY HCV GENOTYPE 1A FROM A DOMINANT CD8+ T CELL RESPONSE BY SELECTION OF ALTERED EPITOPE PROCESSING (2014) (2)
HEMATOPOIESIS AND STEM CELLS BLT-humanized C 57 BL / 6 Rag 2 2 / 2 g c 2 / 2 CD 47 2 / 2 mice are resistant to GVHD and develop Band T-cell immunity to HIV infection (2013) (2)
HLA FOOTPRINTS ON HIV-1 ARE ASSOCIATED WITH 1 (2009) (1)
IDENTIFICATION OF GENETICALLY RELATED HCV INFECTIONS AMONG SELF-DESCRIBED INJECTING PARTNERSHIPS (2021) (1)
Fine specificity and cross-clade reactivity of HIV-1 Gag-specific CD4+ T cells (2008) (1)
Immunologic evidence for lack of heterologous protection following resolution of HCV infection (2007) (1)
Early immune adaptation in HIV-1 revealed by population-level approaches (2014) (1)
Temporal effect of HLA-B*57 on viral control during primary HIV-1 infection (2013) (1)
T cell receptor clonotypes modulate the protective effect of HLA class I alleles in HIV-1 infection (2013) (1)
HIV Minor Variants Detected by Next Generation Sequencing: Impact on Immune Control of HIV in the Context of HLA-B*27:05 and HLA-B*57:01 (2014) (0)
Response Emergence of a Variant-Specific CTL HIV-1 Viral Escape in Infancy Followed by Altfeld , (2005) (0)
flexibility of the HIV-specific TCR repertoire T-cell clonotypes demonstrate + Fluctuations of functionally distinct CD 8 (2006) (0)
HLA Footprints in HIV-1 Drive Phylogenetic Clustering and Inter-Clade Variation (2008) (0)
Primate (Nonhuman) Immune System (1998) (0)
Impairment of Gag-Speciﬁc CD8 (cid:1) T-Cell Function in Mucosal and Systemic Compartments of Simian Immunodeﬁciency Virus mac251- and Simian-Human Immunodeﬁciency Virus KU2-Infected Macaques (2001) (0)
Reply to Colson and Gerolami (2011) (0)
Sa1525 – Visne Analysis of Hepatitis C Virus-Specific Cd8 T Cells from Direct Acting Antiviral-Treated Chronic Hcv Patients and Hcv Resolvers (2019) (0)
University of Birmingham High resolution sequencing of hepatitis C virus reveals limited intra-hepatic compartmentalization in end stage liver disease (2016) (0)
Characterizing the T cell receptor clonotype repertoire of an atypical HLA class II-restricted CD8 T cell response in HIV-1 infection (VIR6P.1170) (2015) (0)
CD8+ T cell escape of HCV by selection of a polymorphism in the epitope flanking region that impairs antigen processing and presentation (2013) (0)
Testing Implications for Vaccine Design and Complex Class I Molecule Mamu-A * 01 : Bound by the Major Histocompatibility Macaques Recognize 14 Different Epitopes Immunodeficiency Virus-Infected Rhesus Lymphocytes from Simian + CD 8 (2000) (0)
Seltene Escapemutationen in einem HLA-B27 restringierten CD8+ T-Zell-Epitop erfordern kompensatorische Mutationen (2010) (0)
HIV Superinfection and Immune Control: Implications for Vaccine Development? (2002) (0)
Reversion of HLA-Associated Polymorphisms in GAG, POL and NEF during the first year of HIV infection: Sites, Rates and pVL correlations (2008) (0)
High Level of PD-1 Expression on Hepatitis C Virus (HCV)-Speciﬁc CD8 (cid:1) and CD4 (cid:1) T Cells during Acute HCV Infection, Irrespective of Clinical Outcome (cid:1) (2008) (0)
Hepatitis C Virus Transmission Clusters in Public Health and Correctional Settings, Wisconsin, USA, 2016–2017 (2021) (0)
carlsonSelectionBias--supplementary data (2014) (0)
418 Longitudinal full length sequencing reveals mutations consistent with selective immune pressures by CTL (2004) (0)
P.337 Rational design of HCV vaccine cocktails that maximize coverage of potential CTL epitopes (2006) (0)
Capturing sequence diversity in metagenomes with comprehensive and scalable probe design (2019) (0)
TAILORED DC INDUCE PROTECTIVE HIV-1 SPECIFIC POLYFUNCTIONAL CD8+ T CELLS IN THE LYMPHOID TISSUE FROM HUMANIZED BLT MICE (2021) (0)
P.199 Dominant and subdominant T-cell responses and viral evolution in subjects with acute symptomatic HCV infection (2006) (0)
CD4 functionality determines outcome in acute HCV re-infection (2008) (0)
Regimen Vaccinia Virus Ankara Boost Vaccination Multiepitope Gene and DNA Prime-Modified T Lymphocytes in Macaques by Using a Immunodeficiency Virus-Specific Cytotoxic Effective Induction of Simian (1999) (0)
Epitope sharing as a consequence of limited MHC class I polymorphism and sequence variation in the cotton-top tamarin (1996) (0)
Functional Homologs to Human Pseudogenes Repertoire in Chimpanzees : Identification of Variable Gene β Analysis of the TCR (2003) (0)
Supplementary Materials for Selection Bias at the HIV-1 Transmission Bottleneck (2014) (0)
[463] DETECTION OF CD4+ T CELL RESPONSES IN PATIENTS WITH ACUTE HCV INFECTION IRRESPECTIVE OF CLINICAL OUTCOME (2007) (0)
Methode de vaccination visant a l'induction efficace d'une reponse aux lymphocytes t cytotoxiques (2000) (0)
Stereotypic escape from CD8+ T-cell responses represents a major driving force of HIV-1 sequence diversity and reveals constraints on HIV-1 evolution (2005) (0)
3 POPULATIONAL ANALYSIS REVEALS A LINK BETWEEN COMPLEX VIRAL ESCAPE FROM CD8+ T-CELL RESPONSES AND PROTECTION IN HCV INFECTION (2011) (0)
Peptides with Arginine at P2 Sequence Similarity to HLA-B27 that Binds an MHC Class I Molecule with Only Limited Gorillas with Spondyloarthropathies Express (2001) (0)
Sites and kinetics of HLA-associated immune escape in HIV-1 integrase (2009) (0)
Rapid HIV disease progression following superinfection in an HLA-B*27:05/B*57:01-positive transmission recipient (2018) (0)
Hepatitis C Virus (HCV) Sequence Variation Induces an HCV-Specific T-Cell Phenotype Analogous to Spontaneous Resolution (vol 84, pg 1656, 2010) (2011) (0)
Interferon-I: The Pièce de Résistance of HIV-1 Transmission? (2017) (0)
Improves Detection of HIV-Specific T Cell Increased Sequence Diversity Coverage (2007) (0)
Cross reactive TCR modulate the antiviral efficacy of protective HLA class I alleles (67.17) (2011) (0)
Disease progression despite protective HLA expression in an HIV-infected transmission pair (2015) (0)
P206 Hepatitis C Virus Compartmentalisation: Unravelling Genetic Complexity Within The Liver (2014) (0)
Hepatitis C Virus (HCV) Sequence Variation Induces an HCV-Specific T-Cell Phenotype Analogous to Spontaneous Resolution (2011) (0)
Subtype B Gag Proteins Human Immunodeficiency Virus Type 1 Escape-Associated Fitness Costs in the Cytotoxic-T-Lymphocyte Frequent and Variable (2014) (0)
Broadly reactive neutralizing activity in HIV-1 infected injecting drug users (2016) (0)
Transmission Clusters of Hepatitis C Virus among Public Health and Correctional Settings from Wisconsin, 2016-2017 (2020) (0)
400 Longitudinal full genome sequencing to assess the extent of CD8+ CTL escape in HCV (2003) (0)
Protection from persistent hepatitis C virus infection by HLA class I: The need for multiple escape mutations in immunodominant T cell epitopes is a common feature (2011) (0)
In vivo plasma LPS levels in HIV negative subjects alter T cell proliferative responses, stimulate cytokine release and induce TLR cross tolerance in monocytes ex vivo (IRC4P.604) (2015) (0)
Fluctuations of functionally distinct CD8 (cid:1) T-cell clonotypes demonstrate ﬂexibility of the HIV-speciﬁc TCR repertoire (2006) (0)
P.191 HLA-associated sequence polymorphisms in HCV reveal the reproducibility of immune responses and constraints on viral evolution (2006) (0)
HLA Footprints on Human Immunodeficiency Virus Type 1 Are Associated with Interclade Polymorphisms and Intraclade Phylogenetic Clustering (2011) (0)
O.187 Differential responsiveness of CD4 and CD8 T-cells during acute HCV re-infection (2006) (0)
622 COMPREHENSIVE ASSESSMENT OF HCV CD4+ EPITOPES THROUGH CONVENTIONAL MAPPING COMBINED WITH COMPUTATIONAL ANALYSIS (2008) (0)
P.163 Forces driving viral sequence evolution in acute hepatitis C infection (2006) (0)
Tailoring of hepatitis C virus escape from an HLA-B27 restricted CD8+ T cell epitope (2010) (0)

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