Tom Brown

Q: What Schools Are Affiliated With Tom Brown

Tom Brown is affiliated with the following schools: Imperial College London, University of Oxford, University of Edinburgh, University of Southampton, University of Bradford

Tom Brown 's AcademicInfluence.com Rankings

Tom Brown

Chemistry

#2199

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#3074

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chemistry Degrees

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Chemistry

Tom Brown 's Degrees

PhD Chemistry University of Oxford
Bachelors Chemistry University of Oxford

Why Is Tom Brown Influential?

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According to Wikipedia, Tom Brown FRSC FRSE is a British chemist, biotechnologist, and entrepreneur. He is the Professor of Nucleic acid chemistry at the Department of Chemistry and Department of Oncology at the University of Oxford. Currently, he is serving as the President of the Chemical Biology Interface Division of the Royal Society of Chemistry. He is best known for his contribution in the field of DNA Repair, DNA Click chemistry, and in the application of Molecular genetics in forensics and diagnostics.

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Tom Brown 's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Detection of PCR products using self-probing amplicons and fluorescence (1999) (714)
Click chemistry with DNA. (2010) (490)
Mode of action and application of Scorpion primers to mutation detection. (2000) (353)
Crystal Structure of a G:T/U Mismatch-Specific DNA Glycosylase Mismatch Recognition by Complementary-Strand Interactions (1998) (239)
Template-directed oligonucleotide strand ligation, covalent intramolecular DNA circularization and catenation using click chemistry. (2007) (223)
Crystal structure of a DNA duplex containing 8-hydroxydeoxyguanine-adenine base pairs. (1994) (204)
Fluorescence based strategies for genetic analysis. (2005) (198)
The crystal structure of d(G-G-G-G-C-C-C-C). A model for poly(dG).poly(dC). (1985) (193)
Quenching of CdSe quantum dot emission, a new approach for biosensing. (2005) (192)
Diagonal multi-matrix correlators and BPS operators in N=4 SYM (2007) (183)
Molecular structure of the G.A base pair in DNA and its implications for the mechanism of transversion mutations. (1986) (162)
Duplex Scorpion primers in SNP analysis and FRET applications. (2001) (150)
Click Nucleic Acid Ligation: Applications in Biology and Nanotechnology (2012) (150)
Diagonal free field matrix correlators, global symmetries and giant gravitons (2008) (150)
Highly Sensitive DNA Sensor Based on Upconversion Nanoparticles and Graphene Oxide. (2015) (148)
Nucleic acid base analog FRET-pair facilitating detailed structural measurements in nucleic acid containing systems. (2009) (148)
SERS-melting: a new method for discriminating mutations in DNA sequences. (2008) (143)
High throughput measurement of duplex, triplex and quadruplex melting curves using molecular beacons and a LightCycler. (2002) (142)
The structure of guanosine-thymidine mismatches in B-DNA at 2.5-A resolution. (1993) (141)
Intramolecular DNA quadruplexes with different arrangements of short and long loops (2007) (137)
The contribution of cytosine protonation to the stability of parallel DNA triple helices. (1998) (124)
Characterization and use of an unprecedentedly bright and structurally non-perturbing fluorescent DNA base analogue (2007) (121)
Sequence effects of single base loops in intramolecular quadruplex DNA (2007) (120)
Crystal structure of a thwarted mismatch glycosylase DNA repair complex (1999) (119)
Biocompatible artificial DNA linker that is read through by DNA polymerases and is functional in Escherichia coli (2011) (118)
Crystal structure of an octameric RuvA-Holliday junction complex. (1998) (117)
Four base recognition by triplex-forming oligonucleotides at physiological pH (2005) (112)
New strategy for the synthesis of chemically modified RNA constructs exemplified by hairpin and hammerhead ribozymes (2010) (112)
Click Chemistry with DNA (2010) (110)
Effect of G-tract length on the topology and stability of intramolecular DNA quadruplexes. (2007) (108)
Synthesis and physical properties of anti-HIV antisense oligonucleotides bearing terminal lipophilic groups (1992) (106)
An autonomous molecular assembler for programmable chemical synthesis. (2016) (104)
Crystal structure of a berenil‐dodecanucleotide complex: the role of water in sequence‐specific ligand binding. (1990) (101)
High-resolution structure of a DNA helix containing mismatched base pairs (1985) (97)
Fluorescent properties of DNA base analogue tC upon incorporation into DNA — negligible influence of neighbouring bases on fluorescence quantum yield (2005) (97)
The crystal structure of d(GGATGGGAG) forms an essential part of the binding site for transcription factor IIIA (1986) (95)
HyBeacon probes: a new tool for DNA sequence detection and allele discrimination. (2001) (95)
Graphene Oxide-Upconversion Nanoparticle Based Optical Sensors for Targeted Detection of mRNA Biomarkers Present in Alzheimer's Disease and Prostate Cancer. (2017) (91)
Chiral phosphorothioate analogues of B-DNA. The crystal structure of Rp-d[Gp(S)CpGp(S)CpGp(S)C]. (1986) (90)
Multiplexed mRNA Sensing and Combinatorial-Targeted Drug Delivery Using DNA-Gold Nanoparticle Dimers. (2018) (89)
Affinity of mismatch-binding protein MutS for heteroduplexes containing different mismatches. (2001) (89)
Synthesis and polymerase chain reaction amplification of DNA strands containing an unnatural triazole linkage. (2009) (86)
Comparison of the thermodynamic stabilities and solution conformations of DNA.RNA hybrids containing purine-rich and pyrimidine-rich strands with DNA and RNA duplexes. (1996) (86)
Fast copper-free click DNA ligation by the ring-strain promoted alkyne-azide cycloaddition reaction. (2011) (85)
Solution structures of DNA.RNA hybrids with purine-rich and pyrimidine-rich strands: comparison with the homologous DNA and RNA duplexes. (1998) (85)
Interaction of berenil with the EcoRI dodecamer d(CGCGAATTCGCG)2 in solution studied by NMR. (1991) (85)
High-resolution structure of a mutagenic lesion in DNA. (1990) (83)
A label-free, electrochemical SERS-based assay for detection of DNA hybridization and discrimination of mutations. (2012) (82)
Tension induces a base-paired overstretched DNA conformation (2012) (79)
G . T base-pairs in a DNA helix: the crystal structure of d(G-G-G-G-T-C-C-C). (1985) (79)
Influence of pH on the conformation and stability of mismatch base-pairs in DNA. (1990) (79)
A Hitchhiker's Guide to Click-Chemistry with Nucleic Acids. (2021) (77)
Crystal structure and stability of a DNA duplex containing A(anti).G(syn) base-pairs. (1989) (77)
Structural and thermodynamic studies on the adenine.guanine mismatch in B-DNA. (1990) (77)
Rapid and Efficient DNA Strand Cross‐Linking by Click Chemistry (2008) (73)
DNA adopts normal B-form upon incorporation of highly fluorescent DNA base analogue tC: NMR structure and UV-Vis spectroscopy characterization. (2004) (70)
Hydroxylation of methylated CpG dinucleotides reverses stabilisation of DNA duplexes by cytosine 5-methylation. (2011) (67)
5-(1-propargylamino)-2'-deoxyuridine (UP): a novel thymidine analogue for generating DNA triplexes with increased stability. (1999) (66)
Gold nanoparticles and fluorescently-labelled DNA as a platform for biological sensing. (2013) (65)
Genomic sequence correction by single‐stranded DNA oligonucleotides: role of DNA synthesis and chemical modifications of the oligonucleotide ends (2005) (65)
Novel Method for Detection, Typing, and Quantification of Human Papillomaviruses in Clinical Samples (2001) (64)
Transcription of Click-Linked DNA in Human Cells** (2014) (63)
Do C-H...O hydrogen bonds contribute to the stability of nucleic acid base pairs? (1995) (62)
DNA duplexes stabilized by modified monomer residues: synthesis and stability (1998) (60)
Coralyne has a preference for intercalation between TA.T triples in intramolecular DNA triple helices. (1997) (60)
Graphene Oxide-Upconversion Nanoparticle Based Portable Sensors for Assessing Nutritional Deficiencies in Crops. (2018) (60)
Structural and mechanistic basis of penicillin-binding protein inhibition by lactivicins (2007) (60)
Non-covalent single transcription factor encapsulation inside a DNA cage. (2013) (59)
Structural insights into how 5-hydroxymethylation influences transcription factor binding. (2014) (59)
Triplex addressability as a basis for functional DNA nanostructures. (2007) (58)
Very stable mismatch duplexes: structural and thermodynamic studies on tandem G.A mismatches in DNA. (1992) (57)
Replication Fork Reversal during DNA Interstrand Crosslink Repair Requires CMG Unloading (2018) (57)
Naphthalenyl-and anthracenyl-ethynyl dT analogues as base discriminating fluorescent nucleosides and intramolecular energy transfer donors in oligonucleotide probes (2007) (56)
Ultrasensitive fluorescence-based methods for nucleic acid detection: towards amplification-free genetic analysis. (2011) (55)
Refined crystal structure of an octanucleotide duplex with G . T mismatched base-pairs. (1986) (54)
Thermodynamic and kinetic stability of intermolecular triple helices containing different proportions of C+*GC and T*AT triplets. (2003) (53)
Copper-free click chemistry as an emerging tool for the programmed ligation of DNA-functionalised gold nanoparticles. (2013) (53)
Dynamics of the 4D genome during in vivo lineage specification and differentiation (2020) (53)
Crystal and molecular structure of r(CGCGAAUUAGCG): an RNA duplex containing two G(anti).A(anti) base pairs. (1994) (52)
Structural features and hydration of d(C-G-C-G-A-A-T-T-A-G-C-G); a double helix containing two G.A mispairs. (1986) (52)
Fast and efficient DNA crosslinking and multiple orthogonal labelling by copper-free click chemistry. (2012) (52)
Fast and efficient DNA crosslinking and multiple orthogonal labelling by copper-free click chemistry. (2012) (52)
Comparison of the electrophoretic and hydrodynamic properties of DNA and RNA oligonucleotide duplexes. (1997) (51)
Redox Capacitive Assaying of C-Reactive Protein at a Peptide Supported Aptamer Interface. (2018) (50)
Formation of stable DNA triplexes. (2011) (50)
Functionalizing Designer DNA Crystals with a Triple-Helical Veneer (2014) (50)
Synthesis and properties of DNA-PNA chimeric oligomers. (1996) (50)
Assembly of a biocompatible triazole-linked gene by one-pot click-DNA ligation. (2017) (49)
A Very Stable Cyclic DNA Miniduplex with Just Two Base Pairs (2008) (49)
Membrane-anchored DNA assembly for energy and electron transfer. (2009) (49)
Addressable high-information-density DNA nanostructures (2007) (49)
Structural features and hydration of a dodecamer duplex containing two C.A mispairs. (1987) (49)
Phospholipid membranes decorated by cholesterol-based oligonucleotides as soft hybrid nanostructures. (2008) (49)
RPA activates the XPF‐ERCC1 endonuclease to initiate processing of DNA interstrand crosslinks (2017) (48)
Conformation of guanine-8-oxoadenine base pairs in the crystal structure of d(CGCGAATT(O8A)GCG). (1992) (48)
Inosine.adenine base pairs in a B-DNA duplex. (1987) (48)
NMR assignments and solution conformation of the DNA.RNA hybrid duplex d(GTGAACTT).r(AAGUUCAC). (1993) (47)
Further studies on the protection of histidine side chains in peptide synthesis: the use of the π-benzyloxymethyl group (1982) (47)
Self-association of a DNA loop creates a quadruplex: crystal structure of d(GCATGCT) at 1.8 A resolution. (1995) (46)
Efficient RNA synthesis by in vitro transcription of a triazole-modified DNA template. (2011) (46)
Barnase has subsites that give rise to large rate enhancements. (1992) (45)
Chiral phosphorothioate analogues of B-DNA: The crystal structure of Rp-d¦Gp(S)CpGp(S)CpGp(S)C¦☆ (1993) (45)
Correlators, probabilities and topologies in = 4 SYM (2006) (45)
Functionalized nanostructures: redox-active porphyrin anchors for supramolecular DNA assemblies. (2010) (45)
Structural characterisation of the bromouracil.guanine base pair mismatch in a Z-DNA fragment. (1986) (44)
An extra dimension in nucleic acid sequence recognition (2005) (43)
CONFORMATIONAL AND THERMODYNAMIC PROPERTIES OF PARALLEL INTRAMOLECULAR TRIPLE HELICES CONTAINING A DNA, RNA, OR 2'-OMEDNA THIRD STRAND (1999) (43)
Direct Measurement of the Substrate Preference of Uracil-DNA Glycosylase* (1998) (43)
Self-assembled DNA-based fluorescence waveguide with selectable output. (2011) (43)
Characterization of photophysical and base-mimicking properties of a novel fluorescent adenine analogue in DNA (2011) (42)
Recognition of CG inversions in DNA triple helices by methylated 3H-pyrrolo[2,3-d]pyrimidin-2(7H)-one nucleoside analogues. (2005) (42)
An artificial triazole backbone linkage provides a split-and-click strategy to bioactive chemically modified CRISPR sgRNA (2019) (41)
Conformational properties of the G.G mismatch in d(CGCGAATTGGCG)2 determined by NMR. (1992) (40)
A New Platinum Anticancer Drug Forms a Highly Stereoselective Adduct with Duplex DNA. (1999) (40)
Attachment of vitamin E derivatives to oligonucleotides during solid-phase synthesis (1992) (40)
A new base-stable linker for solid-phase oligonucleotide synthesis (1989) (40)
Stable DNA triple helix formation using oligonucleotides containing 2'-aminoethoxy,5-propargylamino-U. (2002) (39)
Assessing the biocompatibility of click-linked DNA in Escherichia coli (2012) (39)
The crystal structure of the RNA/DNA hybrid r(GAAGAGAAGC). d(GCTTCTCTTC) shows significant differences to that found in solution. (1999) (39)
Solution conformation of a deoxynucleotide containing tandem G.A mismatched base pairs and 3'-overhanging ends in d(GTGAACTT)2. (1992) (39)
INSIGHT: A population-scale COVID-19 testing strategy combining point-of-care diagnosis with centralized high-throughput sequencing (2020) (39)
Synthesis and oligonucleotide incorporation of fluorescent cytosine analogue tC: a promising nucleic acid probe (2007) (38)
Structure and dynamics of triazole-linked DNA: biocompatibility explained. (2011) (38)
Permutations and the loop (2008) (38)
Toward Complete Sequence Flexibility of Nucleic Acid Base Analogue FRET. (2017) (38)
Selectivity and affinity of triplex-forming oligonucleotides containing 2'-aminoethoxy-5-(3-aminoprop-1-ynyl)uridine for recognizing AT base pairs in duplex DNA. (2004) (37)
5-Formylcytosine does not change the global structure of DNA (2017) (37)
Stable recognition of TA interruptions by triplex forming oligonucleotides containing a novel nucleoside. (2005) (37)
Solution conformation of a parallel DNA triple helix with 5' and 3' triplex-duplex junctions. (1999) (37)
Di-copper metallodrugs promote NCI-60 chemotherapy via singlet oxygen and superoxide production with tandem TA/TA and AT/AT oligonucleotide discrimination (2018) (36)
Efficient reverse click labeling of azide oligonucleotides with multiple alkynyl Cy-Dyes applied to the synthesis of HyBeacon probes for genetic analysis (2012) (36)
Molecular beacons attached to glass beads fluoresce upon hybridisation to target DNA (2000) (35)
Modern Machine‐Aided Methods of Oligodeoxyribonucleotide Synthesis (1992) (35)
Denaturation of dsDNA immobilised at a negatively charged gold electrode is not caused by electrostatic repulsion (2013) (35)
Refined crystal structure of an octanucleotide duplex with I.T. mismatched base pairs. (1993) (34)
Conformational properties and thermodynamics of the RNA duplex r(CGCAAAUUUGCG)2: comparison with the DNA analogue d(CGCAAATTTGCG)2 (1997) (34)
Hydration of the RNA duplex r(CGCAAAUUUGCG)2 determined by NMR. (1996) (34)
The orientation and dynamics of the C2'-OH and hydration of RNA and DNA.RNA hybrids (1998) (34)
Guanine-1,N6-ethenoadenine base pairs in the crystal structure of d(CGCGAATT(epsilon dA)GCG). (1994) (33)
Quadracyclic adenine: a non-perturbing fluorescent adenine analogue. (2012) (33)
Anthracycline binding to DNA. High-resolution structure of d(TGTACA) complexed with 4'-epiadriamycin. (1992) (33)
The structure of FemX(Wv) in complex with a peptidyl-RNA conjugate: mechanism of aminoacyl transfer from Ala-tRNA(Ala) to peptidoglycan precursors. (2013) (32)
Triplex-directed recognition of a DNA nanostructure assembled by crossover strand exchange. (2012) (32)
Submicron patterning of DNA oligonucleotides on silicon. (2004) (32)
An approach to enzyme inhibition employing reversible boronate ester formation (2011) (32)
Anthracycline-DNA interactions at unfavourable base-pair triplet-binding sites: structures of d(CGGCCG)/daunomycin and d(TGGCCA)/adriamycin complexes. (1993) (32)
Azide and trans-cyclooctene dUTPs: incorporation into DNA probes and fluorescent click-labelling. (2015) (32)
DNA polymorphism as an origin of adenine-thymine tract length-dependent threading intercalation rate. (2008) (31)
Modulation of density and orientation of amphiphilic DNA anchored to phospholipid membranes. I. Supported lipid bilayers. (2010) (31)
Use of inter-proton nuclear Overhauser effects to assign the nuclear magnetic resonance spectra of oligodeoxynucleotide and hybrid duplexes in aqueous solution. (1983) (31)
Rapid chemical ligation of oligonucleotides by the Diels-Alder reaction. (2011) (30)
The Sedimentation of Colloidal Nanoparticles in Solution and Its Study Using Quantitative Digital Photography (2017) (30)
Reversible Ligation of Programmed DNA-Gold Nanoparticle Assemblies. (2015) (30)
Solid phase click ligation for the synthesis of very long oligonucleotides. (2013) (30)
A new modular approach to nanoassembly: stable and addressable DNA nanoconstructs via orthogonal click chemistries. (2012) (30)
Solution conformation of an intramolecular DNA triplex containing a nonnucleotide linker: comparison with the DNA duplex. (1997) (29)
The dependence of DNase I activity on the conformation of oligodeoxynucleotides. (1997) (29)
A new fixation strategy for addressable nano-network building blocks. (2010) (29)
Enzymatic incorporation and fluorescent labelling of cyclooctyne-modified deoxyuridine triphosphates in DNA. (2014) (29)
A highly fluorescent DNA toolkit: synthesis and properties of oligonucleotides containing new Cy3, Cy5 and Cy3B monomers (2012) (29)
Nanopore sequencing of single-cell transcriptomes with scCOLOR-seq (2021) (28)
Nanopore sequencing of single-cell transcriptomes with scCOLOR-seq (2021) (28)
Efficient enzymatic synthesis and dual-colour fluorescent labelling of DNA probes using long chain azido-dUTP and BCN dyes (2016) (28)
Tyrosine 27 of the specificity polypeptide of EcoKI can be UV crosslinked to a bromodeoxyuridine-substituted DNA target sequence. (1995) (28)
The conformational variability of an adenosine.inosine base-pair in a synthetic DNA dodecamer. (1992) (27)
Synthesis of fluorophore and quencher monomers for use in scorpion primers and nucleic acid structural probes. (2003) (27)
2'-Alkynylnucleotides: A Sequence- and Spin Label-Flexible Strategy for EPR Spectroscopy in DNA. (2016) (27)
Closed nanoconstructs assembled by step-by-step ss-DNA coupling assisted by phospholipid membranes (2009) (27)
Flexible acoustic particle manipulation device with integrated optical waveguide for enhanced microbead assays. (2009) (26)
Interrogation of short tandem repeats using fluorescent probes and melting curve analysis: a step towards rapid DNA identity screening. (2008) (26)
Combined nucleobase and backbone modifications enhance DNA duplex stability and preserve biocompatibility (2014) (26)
Using surface-enhanced Raman spectroscopy and electrochemically driven melting to discriminate Yersinia pestis from Y. pseudotuberculosis based on single nucleotide polymorphisms within unpurified polymerase chain reaction amplicons. (2015) (26)
First synthesis of 1-deazacytidine, the C-nucleoside analogue of cytidine (2002) (26)
A Raman probe for selective wrapping of single-walled carbon nanotubes by DNA (2007) (25)
Preparation and characterization of manganese, cobalt and zinc DNA nanoflowers with tuneable morphology, DNA content and size (2018) (25)
Crystal structure of the Escherichia coli dcm very-short-patch DNA repair endonuclease bound to its reaction product-site in a DNA superhelix. (2003) (25)
Simultaneous MLPA-based multiplex point mutation and deletion analysis of the Dystrophin gene (2007) (25)
Synthesis of HyBeacons and dual-labelled probes containing 2'-fluorescent groups for use in genetic analysis. (2003) (25)
Six‐Colour HyBeacon Probes for Multiplex Genetic Analysis (2010) (25)
A trigonal form of the idarubicin:d(CGATCG) complex; crystal and molecular structure at 2.0 A resolution. (1995) (24)
Protection of histidine side-chains with π-benzyloxymethyl- or π-bromobenzyloxymethyl-groups (1981) (24)
Potent Triple Helix Stabilization by 5′,3′‐Modified Triplex‐Forming Oligonucleotides (2009) (24)
High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale (2021) (24)
Thermodynamic stability and solution conformation of tandem G.A mismatches in RNA and RNA.DNA hybrid duplexes. (1994) (24)
Sequence-dependent bending of DNA induced by cisplatin: NMR structures of an A.T-rich 14-mer duplex. (2000) (24)
The solution structure of a DNA*RNA duplex containing 5-propynyl U and C; comparison with 5-Me modifications. (2003) (24)
Chemical modification and micropatterning of Si(100) with oligonucleotides (2004) (24)
The crystal structure analysis of d(CGCGAASSCGCG)2, a synthetic DNA dodecamer duplex containing four 4'-thio-2'-deoxythymidine nucleotides. (1996) (24)
Complex matrix model duality (2010) (24)
Improved synthesis of 5-hydroxymethyl-2'-deoxycytidine phosphoramidite using a 2'-deoxyuridine to 2'-deoxycytidine conversion without temporary protecting groups. (2011) (23)
NMR analyses on N-hydroxymethylated nucleobases – implications for formaldehyde toxicity and nucleic acid demethylases† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8ob00734a (2018) (23)
Nanofabrication yields. Hybridization and click-fixation of polycyclic DNA nanoassemblies. (2011) (23)
Pentacyclic adenine: a versatile and exceptionally bright fluorescent DNA base analogue† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc05448c (2018) (23)
Reversible Energy-Transfer Switching on a DNA Scaffold (2015) (23)
Initial DNA Interactions of the Binuclear Threading Intercalator Λ,Λ-[μbidppz(bipy)4Ru2]4+: An NMR Study with [d(CGCGAATTCGCG)]2** (2013) (23)
Investigating d-lysine stereochemistry for epigenetic methylation, demethylation and recognition. (2017) (22)
Light-Induced Reversible DNA Ligation of Gold Nanoparticle Superlattices. (2019) (22)
Sensing of Vimentin mRNA in 2D and 3D Models of Wounded Skin Using DNA-Coated Gold Nanoparticles. (2018) (22)
Molecular Requirements of High-Fidelity Replication-Competent DNA Backbones for Orthogonal Chemical Ligation. (2017) (22)
Modulation of density and orientation of amphiphilic DNA on phospholipid membranes. II. Vesicles. (2010) (22)
Non-Watson-Crick base associations in DNA and RNA revealed by single crystal x-Ray diffraction methods: Mismatches, modified bases, and nonduplex DNA (1997) (21)
The effect of base-pair sequence on electrochemically driven denaturation. (2012) (21)
Using linkers to investigate the spatial separation of the conserved nucleotides A9 and G12 in the hammerhead ribozyme. (1994) (21)
DNA triple helix formation at target sites containing several pyrimidine interruptions: stabilization by protonated cytosine or 5-(1-propargylamino)dU. (1999) (21)
CG base pair recognition within DNA triple helices by modified N-methylpyrrolo-dC nucleosides. (2010) (21)
Stabilisation of self-assembled DNA crystals by triplex-directed photo-cross-linking. (2016) (21)
Force-induced melting of DNA—evidence for peeling and internal melting from force spectra on short synthetic duplex sequences (2014) (21)
Triplex staples: DNA double-strand cross-linking at internal and terminal sites using psoralen-containing triplex-forming oligonucleotides. (2006) (21)
Half-BPS SU(N) correlators in = 4 SYM (2007) (21)
Properties of multiple G.A mismatches in stable oligonucleotide duplexes. (1994) (20)
Exceptionally slow kinetics of the intramolecular quadruplex formed by the Oxytricha telomeric repeat. (2005) (20)
DNA closed nanostructures: a structural and Monte Carlo simulation study. (2008) (20)
Epigenetic Modifications of Cytosine: Biophysical Properties, Regulation, and Function in Mammalian DNA. (2018) (20)
Platform for controlled supramolecular nanoassembly. (2009) (20)
DNA-Coated Gold Nanoparticles for the Detection of mRNA in Live Hydra Vulgaris Animals. (2018) (20)
The molecular structure of a 4'-epiadriamycin complex with d(TGATCA) at 1.7A resolution: comparison with the structure of 4'-epiadriamycin d(TGTACA) and d(CGATCG) complexes. (1992) (20)
DNA sequence recognition by an isopropyl substituted thiazole polyamide. (2004) (20)
Controlled release of chol-TEG-DNA from Nano- and micropatterned SU-8 surfaces by a spreading lipid film. (2008) (20)
Specifically horizontally tethered DNA probes on Au surfaces allow labelled and label-free DNA detection using SERS and electrochemically driven melting (2015) (20)
Recognition of GT mismatches by Vsr mismatch endonuclease (2000) (20)
Linear fluorescent oligonucleotide probes with an acridine quencher generate a signal upon hybridisation (2001) (19)
Locked nucleic acid (LNA) enhances binding affinity of triazole-linked DNA towards RNA† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7cc05159j (2017) (19)
Synthesis and evaluation of a new non-fluorescent quencher in fluorogenic oligonucleotide probes for real-time PCR. (2005) (19)
DNA sequence specificity of triplex-binding ligands. (2003) (19)
CRISPRi is not strand-specific at all loci and redefines the transcriptional landscape (2017) (19)
Gauging the flexibility of fluorescent markers for the interpretation of fluorescence resonance energy transfer. (2011) (19)
Sequence-selective metalation of double-helical oligodeoxyribonucleotides with PtII, MnII, and ZnII ions. (2003) (18)
Structure of a DNA base-excision product resembling a cisplatin inter-strand adduct (1998) (18)
Loosening the DNA wrapping around single-walled carbon nanotubes by increasing the strand length (2009) (18)
UV friendly T-parity in the SU(6)/Sp(6) little Higgs model (2010) (18)
Comparison of the solution structures of intramolecular DNA triple helices containing adjacent and non-adjacent CG.C+ triplets. (1998) (18)
Selective killing of cells triggered by their mRNA signature in the presence of smart nanoparticles. (2016) (18)
DNA triplex formation with 5-dimethylaminopropargyl deoxyuridine (2009) (18)
The stability of triplex DNA is affected by the stability of the underlying duplex. (2009) (18)
Synthesis of a novel bis-amino-modified thymidine monomer for use in DNA triplex stabilisation (2000) (17)
The Use of an Electroactive Marker as a SERS Label in an E‐melting Mutation Discrimination Assay (2009) (17)
Real-time surface-enhanced Raman spectroscopy monitoring of surface pH during electrochemical melting of double-stranded DNA. (2012) (17)
Combining nucleoside analogues to achieve recognition of oligopurine tracts by triplex‐forming oligonucleotides at physiological pH (2005) (17)
Analysis of short tandem repeats by using SERS monitoring and electrochemical melting. (2010) (17)
Triplex-directed covalent cross-linking of a DNA nanostructure. (2012) (17)
DNA Gold Nanoparticle Motors Demonstrate Processive Motion with Bursts of Speed Up to 50 nm Per Second. (2021) (16)
Enhanced H-bonding and π-stacking in DNA: a potent duplex-stabilizing and mismatch sensing nucleobase analogue (2014) (16)
Combination probes with intercalating anchors and proximal fluorophores for DNA and RNA detection (2016) (16)
Synthesis of a modified thymidine monomer for site-specific incorporation of reporter groups into oligonucleotides (2001) (16)
Crystallographic and mass spectrometric analyses of a tandem GNAT protein from the clavulanic acid biosynthesis pathway (2010) (15)
Fluorescence Based Strategies for Genetic Analysis (2006) (15)
Cleavage of fragments containing DNA mismatches by enzymic and chemical probes. (2003) (15)
Rapid typing of STRs in the human genome by HyBeacon melting. (2008) (15)
Synthetic oligonucleotide cocktails as probes for detection of human parvovirus B19. (1995) (15)
Structures of CUG Repeats in RNA (2002) (15)
Fluorogenic thiazole orange TOTFO probes stabilise parallel DNA triplexes at pH 7 and above† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc02418a (2018) (15)
Cut-and-join operators and $ \mathcal{N} = 4 $ super Yang-Mills (2010) (15)
A stretched conformation of DNA with a biological role? (2017) (15)
2'-Aminoethoxy-2-amino-3-methylpyridine in triplex-forming oligonucleotides: high affinity, selectivity and resistance to enzymatic degradation. (2011) (15)
Structural basis for the interaction of lactivicins with serine beta-lactamases. (2010) (15)
Thermodynamic Aspects of DNA Nanoconstruct Stability and Design (2009) (14)
Conformations of two duplex forms of d(TCGA) in slow-exchange equilibrium characterized by NMR. (1985) (14)
Synthesis of chemically modified DNA. (2016) (14)
Towards the Targeted Modulation of Gene Expression by Modified Triplex-Forming Oligonucleotides (2008) (14)
Melting temperature measurement and mesoscopic evaluation of single, double and triple DNA mismatches† (2020) (14)
Single tube gene synthesis by phosphoramidate chemical ligation. (2017) (14)
Determining the origin of the stabilization of DNA by 5-aminopropynylation of pyrimidines. (2005) (13)
Efficient self-assembly of DNA-functionalized fluorophores and gold nanoparticles with DNA functionalized silicon surfaces: the effect of oligomer spacers (2013) (13)
Electrospray ionisation-cleavable tandem nucleic acid mass tag–peptide nucleic acid conjugates: synthesis and applications to quantitative genomic analysis using electrospray ionisation-MS/MS (2006) (13)
N.m.r. determination of the solution conformation and dynamics of the A.G mismatch in the d(CGCAAATTGGCG)2 dodecamer. (1991) (13)
Synthesis And Properties Of Oligonucleotides Containing A Cholesterol Thymidine Monomer (2007) (13)
Cg Base Pair Recognition Within Dna Triple Helices Using N -Methyl-3 H -Pyrrolo[2,3- d ]Pyrimidin-2(7 H )-One Nucleoside Analogues (2007) (13)
Binding of 14-3-3 proteins to a single stranded oligodeoxynucleotide aptamer. (2008) (13)
Deuterated water as super solvent for short carbon nanotubes wrapped by DNA (2007) (13)
Getting DNA and RNA out of the dark with 2CNqA: a bright adenine analogue and interbase FRET donor (2020) (13)
Synthesis, Serum Stability and Cell Uptake of Cyclic and Hairpin Decoy Oligonucleotides for TCF/LEF and GLI Transcription Factors (2008) (13)
Kinetic studies on the formation of DNA triplexes containing the nucleoside analogue 2'-O-(2-aminoethyl)-5-(3-amino-1-propynyl)uridine. (2008) (13)
Interaction of oligonucleotide-conjugates with the dipeptide transporter system in Caco-2 cells. (1997) (13)
DNA sequence recognition by an imidazole-containing isopropyl-substituted thiazole polyamide (thiazotropsin B). (2006) (12)
Design of thiazole orange oligonucleotide probes for detection of DNA and RNA by fluorescence and duplex melting† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9ob00885c (2019) (12)
New technologies for DNA analysis--a review of the READNA Project. (2016) (12)
Multi-modal particle manipulator to enhance bead-based bioassays. (2010) (12)
Homogeneous Fluorescent Chemistries for Real-Time PCR (2008) (12)
2′-Substituted 2-amino-3-methylpyridine ribonucleosides in triplex-forming oligonucleotides: triplex stability is determined by chemical environment (2011) (12)
New two dimensional liquid-phase colorimetric assay based on old iodine-starch complexation for the naked-eye quantitative detection of analytes. (2016) (12)
Synthesis and antibody-mediated detection of oligonucleotides containing multiple 2,4-dinitrophenyl reporter groups. (1993) (12)
Discrimination against the cytosine analog tC by Escherichia coli DNA polymerase IV DinB. (2011) (12)
Instrument-free quantitative gold nanoparticle-based liquid-phase colorimetric assays for use in resource-poor environments. (2017) (11)
Synthesis and properties of triplex-forming oligonucleotides containing 2'-O-(2-methoxyethyl)-5-(3-aminoprop-1-ynyl)-uridine. (2010) (11)
Kinetics of diffusion-mediated DNA hybridization in lipid monolayer films determined by single-molecule fluorescence spectroscopy. (2013) (11)
The effect of temperature on electrochemically driven denaturation monitored by SERS. (2015) (11)
Synthesis, Affinity for Complementary RNA and DNA, and Enzymatic Stability of Triazole-Linked Locked Nucleic Acids (t-LNAs) (2018) (11)
Radiolabeled oligonucleotides targeting the RNA subunit of telomerase inhibit telomerase and induce DNA damage in telomerase-positive cancer cells. (2019) (11)
Membrane protrusion coarsening and nanotubulation within giant unilamellar vesicles. (2011) (11)
A comparative study of digoxigenin, 2,4-dinitrophenyl, and alkaline phosphatase as deoxyoligonucleotide labels in non-radioisotopic in situ hybridisation. (1997) (11)
Rapid detection of diagnostic targets using isothermal amplification and HyBeacon probes--a homogenous system for sequence-specific detection. (2015) (11)
Purines, pyrimidines, and imidazoles. Part 53. Synthesis of some 5-halogeno-analogues of metiamide and cimetidine (1980) (10)
Reverse transcription through a bulky triazole linkage in RNA: implications for RNA sequencing. (2014) (10)
A triazole linkage that mimics the DNA phosphodiester group in living systems (2015) (10)
Novel Photocleavable Universal Support for Oligonucleotide Synthesis (2003) (10)
Programming the assembly of gold nanoparticles on graphene oxide sheets using DNA (2015) (10)
End-capped HyBeacon probes for the analysis of human genetic polymorphisms related to warfarin metabolism. (2010) (10)
Advances and challenges in epigenomic single-cell sequencing applications. (2020) (10)
A new dark quencher for use in genetic analysis. (2003) (10)
Triplex-mediated analysis of cytosine methylation at CpA sites in DNA. (2014) (10)
DNA triple-helix formation at target sites containing duplex mismatches. (2006) (10)
Advances and challenges in epigenomic single-cell sequencing applications. (2020) (10)
Rapid mass spectrometric identification of human genomic polymorphisms using multiplexed photocleavable mass-tagged probes and solid phase capture. (2007) (10)
DNA triple helix stabilisation by covalent attachment of a triplex-specific ligand. (1999) (10)
Development of Gene‐Targeted Polypyridyl Triplex‐Forming Oligonucleotide Hybrids (2020) (9)
Towards the use of sporopollenin in drug delivery: Efficient encapsulation of oligonucleotides (2005) (9)
Chapter 1:DNA Recognition by Parallel Triplex Formation (2018) (9)
Using antibodies to control DNA-templated chemical reactions (2020) (9)
Synthesis and biophysical properties of carbamate-locked nucleic acid (LNA) oligonucleotides with potential antisense applications† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9ob00691e (2019) (9)
Oxidative DNA Cleavage with Clip‐Phenanthroline Triplex‐Forming Oligonucleotide Hybrids (2020) (9)
Effects of a hairpin polyamide on DNA melting: comparison with distamycin and Hoechst 33258. (2004) (9)
An analogue of adenine that forms an "A:T" base pair of comparable stability to G:C. (2004) (9)
Molecular flexibility of DNA as a key determinant of RAD51 recruitment (2020) (9)
Squaramide‐Based 5’‐Phosphate Replacements Bind to the DNA Repair Exonuclease SNM1A (2018) (9)
INSIGHT: a scalable isothermal NASBA-based platform for COVID-19 diagnosis (2020) (9)
HyBeacon probes for rapid DNA sequence detection and allele discrimination. (2008) (9)
Synthesis and Antibody Mediated Detection of 2,4-Dinitrophenyl (DNP) Labelled Oligonucleotides (1995) (8)
Thermodynamic stability and drug-binding properties of oligodeoxyribonucleotide duplexes containing 3-deazaadenine:thymine base pairs. (1993) (8)
A DNA sensor based on upconversion nanoparticles and two-dimensional dichalcogenide materials (2021) (8)
Strict conformational demands of RNA cleavage in bulge-loops created by peptidyl-oligonucleotide conjugates (2020) (7)
2′-Alkynyl spin-labelling is a minimally perturbing tool for DNA structural analysis (2020) (7)
Branched poly-labelled oligonucleotides: enhanced specificity of fork-shaped biotinylated oligoribonucleotides for antisense affinity selection. (1993) (7)
The Incorporation of 2,6-Diaminopurine Into Oligodeoxyribonucleotides by the Phosphoramidite Method (1989) (7)
Electrophilic RNA for Peptidyl-RNA Synthesis and Site-Specific Cross-Linking with tRNA-Binding Enzymes. (2016) (7)
Structural analysis of the DNA target site and its interaction with Mbp1. (2009) (7)
Photopatterning of DNA oligonucleotides on silicon surfaces with micron-scale dimensions (2004) (7)
1H-NMR characterization of L-tryptophan binding to TRAP, the trp RNA-binding attenuation protein of Bacillus subtilis. (1996) (7)
DNA‐Targeted Metallodrugs: An Untapped Source of Artificial Gene Editing Technology (2021) (7)
Factors influencing hairpin oligonucleotide cyclization by the uncatalyzed alkyne-azide cycloaddition (AAC) reaction (2010) (7)
The synthesis of oligonucleotides that contain 2,4-dinitrophenyl reporter groups. (1992) (7)
Dot-blot hybridisation assay for detection of parvovirus B19 infections using synthetic oligonucleotides. (1995) (7)
Synthesis of Anthraquinone Oligonucleotides for Triplex Stabilization (2007) (7)
A hydroxamic-acid-containing nucleoside inhibits DNA repair nuclease SNM1A† †Electronic supplementary information (ESI) available: Experimental details for known compounds, NMR spectra of novel compounds, PAMPA experimental details. See DOI: 10.1039/c9ob01133a (2019) (7)
Intramolecular TaqMan probes for genetic analysis. (2002) (6)
Modulation of Mitochondriotropic Properties of Cyanine Dyes by in Organello Copper‐Free Click Reaction (2017) (6)
Expanding the chemical functionality of DNA nanomaterials generated by rolling circle amplification (2021) (6)
Purines, pyrimidines, and imidazoles. Part 51. New syntheses of some 5-alkyl- and 5-dialkyl-aminoimidazoles. 3-Alkylimidazolium nucleosides and 3-alkylpurines (1979) (6)
A SARS-Cov-2 sensor based on upconversion nanoparticles and graphene oxide (2022) (6)
Purines, pyrimidines, and imidazoles. Part 58. Synthesis and reactions of some imidazole-2,4-dicarboxylic acid derivatives (1983) (6)
[1H, 15N] NMR Studies of the Platination of Phosphorothioate Nucleotides − Monofunctional Sulfur Adducts versus Macrochelation (2001) (6)
Squaramides and Ureas: A Flexible Approach to Polymerase‐Compatible Nucleic Acid Assembly (2020) (6)
Consecutive 5'- and 3'-amide linkages stabilise antisense oligonucleotides and elicit an efficient RNase H response. (2020) (6)
Secondary binding sites for heavily modified triplex forming oligonucleotides (2011) (6)
Site-selective immobilization of functionalized DNA origami on nanopatterned Teflon AF (2017) (6)
Shining Light on CRISPR Gene Editing (2020) (5)
Preparation of Synthetic Oligodeoxynucleotide Probes (1996) (5)
Searching for the ideal triazole: Investigating the 1,5-triazole as a charge neutral DNA backbone mimic (2020) (5)
Self-reporting hybridisation assay for miRNA analysis. (2014) (5)
The crystal structure of N(α)-t-butoxycarbonyl-N(π)-benzyloxymethyl-L-histidine (1982) (5)
Stable end-sealed DNA as robust nano-rulers for in vivo single-molecule fluorescence† †Electronic supplementary information (ESI) available: Experimental methods, data analysis routines and Fig. S1–S9. See DOI: 10.1039/c6sc00639f (2016) (5)
Deoxyribonucleic Acid Encoded and Size-Defined Stacking of Perylene Diimides (2021) (5)
Synthesis, oligonucleotide incorporation and fluorescence properties in DNA of a bicyclic thymine analogue (2018) (5)
Direct Detection and Discrimination of Nucleotide Polymorphisms Using Anthraquinone Labeled DNA Probes (2020) (5)
A Mutant of Uracil DNA Glycosylase That Distinguishes between Cytosine and 5-Methylcytosine (2014) (5)
Use of a large Stokes-shift fluorophore to increase the multiplexing capacity of a point-of-care DNA diagnostic device. (2013) (4)
An 111In-labelled bis-ruthenium(ii) dipyridophenazine theranostic complex: mismatch DNA binding and selective radiotoxicity towards MMR-deficient cancer cells† †Electronic supplementary information (ESI) available. See DOI: 10.1039/d0sc02825h (2020) (4)
Self reporting RNA probes as an alternative to cleavable small molecule mass tags. (2012) (4)
Dissection of the 4D chromatin structure of the α-globin locus through in vivo erythroid differentiation with extreme spatial and temporal resolution (2019) (4)
N.m.r. determination of the solution conformation and dynamics of the A.G mismatch in the d(CGCAAATTGGCG)2 dodecamer. (1992) (4)
Gauge/gravity duality beyond the planar limit (2009) (4)
2′-O-Dimethylaminoethoxyuridine and 5-Dimethylaminopropargyl Deoxyuridine for at Base Pair Recognition in Triple Helices (2007) (4)
MISMATCHES IN DNA DUPLEXES (1993) (4)
Spectroscopic and Hydrodynamic Characterisation of DNA-Linked Gold Nanoparticle Dimers in Solution using Two-Photon Photoluminescence. (2018) (4)
CRYSTAL STRUCTURE OF THE RNA/DNA HYBRID R(GAAGAGAAGC). D(GCTTCTCTTC) (1998) (4)
Structure-Based Design of Selective Fat Mass and Obesity Associated Protein (FTO) Inhibitors (2021) (4)
A Click Chemistry Approach to Targeted DNA Crosslinking with cis‐Platinum(II)‐Modified Triplex‐Forming Oligonucleotides (2021) (4)
Synthesis of Lipid-Carbohydrate-Peptidyl-RNA Conjugates to Explore the Limits Imposed by the Substrate Specificity of Cell Wall Enzymes on the Acquisition of Drug Resistance. (2018) (3)
Detection of PCR products from Mycobacterium avium subspecies Paratuberculosis using oligonucleotides containing multiple 2,4-dinitrophenyl reporter groups. (1994) (3)
Stability of the different arms of a DNA tetrahedron and its interaction with a minor groove ligand. (2019) (3)
Lighting Up DNA with the Environment-Sensitive Bright Adenine Analogue qAN4. (2020) (3)
Synthesis of Alkyne‐ and Azide‐Modified Oligonucleotides and Their Cyclization by the CuAAC (Click) Reaction (2008) (3)
An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides (2022) (3)
Nucleic Acid Labeling, Ligation, and Modification (2017) (3)
Engineering Enzyme‐Cleavable Oligonucleotides by Automated Solid‐Phase Incorporation of Cathepsin B Sensitive Dipeptide Linkers (2021) (3)
Dynamics of the 4D genome during lineage specification, differentiation and maturation in vivo (2019) (3)
Gene assembly via one-pot chemical ligation of DNA promoted by DNA nanostructures† †Electronic supplementary information (ESI) available: Experimental procedures, supplementary figures, sequencing data, oligonucleotides sequences. See DOI: 10.1039/c8cc00738a (2018) (3)
Synthesis and use of universal sequence probes in fluorogenic multi-strand hybridisation complexes for economical nucleic acid testing. (2015) (3)
DNA Structural Changes Induced by Intermolecular Triple Helix Formation (2020) (3)
Photoinduced Crosslinking of Double-helical DNA by Psoralen Covalently Linked to a Triple Helix-forming Oligonucleotide under Near-physiological Conditions (2007) (3)
The Mechanism of Dna Repair by Uracil-Dna Glycosylase: Studies Using Nucleotide Analogues (2000) (3)
Hydrogen-Bonding Patterns Observed inthe Base Pairs of Duplex Oligonucleotides (1998) (2)
Synthesis of oligonucleotides labelled with 2,4-dinitrophenyl groups at thymidine sites. (1996) (2)
DNA recognition by triple helix formation (2006) (2)
Peptide nucleic acid probes with charged photocleavable mass markers (2010) (2)
A New 1,5-Disubstituted Triazole DNA Backbone Mimic with Enhanced Polymerase Compatibility (2021) (2)
Transient DNA binding to gapped DNA substrates links DNA sequence to the single-molecule kinetics of protein-DNA interactions (2022) (2)
Prenatal diagnosis for dystrophia myotonica using the polymerase chain reaction (1991) (2)
Synthesis of a Novel Bis-amino-modified Thymidine Monomer for Use in DNA Triplex Stabilization. (2001) (2)
Synthesis of Base Modified Phosphorothioate Oligodeoxynucleotides as Inhibitors of HIV-1 (1991) (2)
Highly accurate barcode and UMI error correction using dual nucleotide dimer blocks allows direct single-cell nanopore transcriptome sequencing (2021) (2)
The structure of an idarubicin-d(TGATCA) complex at high resolution. (1993) (2)
Solution conformation of a deoxynucleotide containing tandem G.cntdot.A mismatched base pairs and 3'-overhanging ends in d(GTGAACTT)2. [Erratum to document cited in CA117(25):247276f] (1993) (2)
Design of thiazole orange oligonucleotide probes for detection of DNA and RNA by ﬂ uorescence and duplex melting † (2019) (2)
Artificial nucleic acid backbones and their applications in therapeutics, synthetic biology and biotechnology (2021) (2)
Targeted high-resolution chromosome conformation capture at genome-wide scale (2020) (2)
Solution conformation of a deoxynucleotide containing tandem G.A mismatched base pairs and 3'-overhanging ends in d(GTGAACTT)2. (1993) (2)
Mismatch detection in homologous strand exchange amplified by hydrophobic effects (2021) (2)
DNA conjugates and sensors (2012) (2)
Molecular flexibility of DNA as a major determinant of RAD51 recruitment (2018) (2)
The stability of duplex DNA containing 3,N4-etheno-2′-deoxycytidine (ÎµdC). A UV melting and high resolution 1H NMR study (1994) (2)
Optimised oligonucleotide substrates to assay XPF-ERCC1 nuclease activity for the discovery of DNA repair inhibitors. (2019) (2)
Enzymatic Synthesis of Chemical Nuclease Triplex-Forming Oligonucleotides with Gene-Silencing Applications (2022) (1)
Dataset for One-pot assembly of a biocompatible triazole-linked gene by click-DNA ligation. (2017) (1)
HyBeacons: A new technology for genetic analysis (2000) (1)
A new approach for the identification of common point mutations within the dystrophin gene using MLPA (2005) (1)
The effect of sequence context on the activity of cytosine DNA glycosylases. (2015) (1)
Edinburgh Research Explorer Pentacyclic adenine: a versatile and exceptionally bright fluorescent DNA base analogue (2018) (1)
“Bind, cleave and leave”: multiple turnover catalysis of RNA cleavage by bulge–loop inducing supramolecular conjugates (2021) (1)
Studies of the structure and stability of base pair mismatches, base pairs involving modified bases, and DNA-drug complexes (1994) (1)
D ec 2 00 7 QMUL-PH-07-23 Diagonal multi-matrix correlators and BPS operators in N = 4 SYM (2008) (1)
Optimising DNA-Coated Gold Nanoparticles to Enrich Skeletal Stem Cells from Human Bone Marrow Samples (2019) (1)
Chemically modified nucleic acids and DNA intercalators as tools for nanoparticle assembly (2021) (1)
CHAPTER 5:Click Chemistry – a Versatile Method for Nucleic Acid Labelling, Cyclisation and Ligation (2012) (1)
THE STRUCTURE OF D(GGGGCCCC) - A MODEL FOR POLY D(G).POLY D(C) (1984) (1)
Nobel Prize 2022 to Sharpless, Meldal, Bertozzi Click Chemistry – molecular lego (2022) (1)
Short-Read Single-Molecule DNA Sequencing for Highly Parallel Analysis of Protein-DNA Interactions (2018) (1)
Photogeneration of Spin Quintet Triplet–Triplet Excitations in DNA-Assembled Pentacene Stacks (2023) (1)
Non-productive MUG-DNA complex (2002) (1)
ine : a versatile and exceptionally bright fl uorescent DNA base analogue † (2018) (1)
Dynamics of the 4D genome during in vivo lineage specification and differentiation (2020) (1)
Protocols for oligonucleotide conjugates. Methods in molecular biology volume 26: edited by Sudhir Agrawal, Humana Press, 1993. US$59.50 (xiv + 377 pages) ISBN 0 896 03252 3 (1994) (1)
Covalently attached intercalators restore duplex stability and splice-switching activity to triazole-modified oligonucleotides (2022) (1)
G:T/U MISMATCH-SPECIFIC DNA GLYCOSYLASE FROM E.COLI (1998) (1)
Engineering functional nanoparticles for delivery in cells (2020) (1)
Curtailing their negativity (2019) (1)
Innenrücktitelbild: Transcription of Click-Linked DNA in Human Cells (Angew. Chem. 9/2014) (2014) (1)
Single cell RNA sequence analysis of human bone marrow samples reveals new targets for isolation of skeletal stem cells using DNA-coated gold nanoparticles (2020) (1)
Erratum: Fast and efficient DNA crosslinking and multiple orthogonal labelling by copper-free click chemistry (Chemical Communications (2012) 48 ((DOI: 10.1039/c2cc35084j)) (2012) (1)
Characterization and use of tricyclic fluorescent nucleic acid base analogues. (2008) (1)
Addressable molecular node assembly--functional DNA nanostructures. (2008) (1)
Inside Back Cover: Transcription of Click‐Linked DNA in Human Cells (Angew. Chem. Int. Ed. 9/2014) (2014) (1)
Journal of Medicinal Chemistry (2010) (1)
HyBeacons®: A novel DNA probe chemistry for rapid genetic analysis (2006) (1)
CRISPRi is not strand-specific and redefines the transcriptional landscape (2017) (1)
Fixation of Self-Assembled DNA Nanostructures by Simultaneous Multicenter Click Chemistry (2010) (1)
"Split-and-Click" sgRNA. (2021) (0)
An Investigation into the Resistance of Spherical Nucleic Acids against DNA Enzymatic Degradation. (2022) (0)
Real-Time Transcription Initiation by E. coli RNA Polymerase in vitro and in vivo (2015) (0)
Naphthalenyl- and Anthracenyl-Ethynyl dT Analogues as Base Discriminating Fluorescent Nucleosides and Intramolecular Energy Transfer Donors in Oligonucleotide Probes. (2007) (0)
The crystal-structure of N(Alpha)-Tert-Butoxycarbonyl-N(Pi)-Benzyloxymethyl-L-Histidine (1982) (0)
Synthetic activated oligonucleotides. Improvements in or relating to synthesis of oligonucleotides (2001) (0)
A membrane anchored DNA-based energy/electron transfer assembly (2015) (0)
INTRAMOLECULAR TRIPLEX, NMR, 10 STRUCTURES (1998) (0)
Crystal structure of a MUG-DNA product complex (2002) (0)
Molecular structure of the GA base pair in DNA and its implications for the mechanism of transversion mutations (x-ray diffraction/mutagenesis/deoxyolignonucleotides/base stacking/tautomer hypothesis) (2016) (0)
DNA, nanoparticles and photons - new approaches for clinical diagnostics (2006) (0)
THE MOLECULAR STRUCTURE OF AN IDARUBICIN-D(TGATCA) COMPLEX AT HIGH RESOLUTION (1993) (0)
zole orange TOTFO probes stabilise parallel DNA triplexes at pH 7 and above † (2018) (0)
ULTRA HIGH RESOLUTION DICKERSON-DREW DODECAMER B-DNA (2013) (0)
DNA TRIPLEX WITH 5' AND 3' JUNCTIONS, NMR, 10 STRUCTURES (1999) (0)
Antibody-mediated detection and physical properties of oligonucleotides labelled with multiple internal and terminal 2,4-dinitrophenyl groups. (1996) (0)
CCDC 1507512: Experimental Crystal Structure Determination (2016) (0)
Crystal structure of a DNA dodecamer containing a tetramethylpyrrolinoxyl (nitroxide) spin label (2020) (0)
60TH ROCKY MOUNTAIN CONFERENCE ON MAGNETIC RESONANCE (2019) (0)
The First All-Nucleobase Analog FRET Pair (2010) (0)
A-TRACT RNA DODECAMER, NMR, 12 STRUCTURES (1997) (0)
Searching for avidity by chemical ligation of combinatorially self-assembled DNA-encoded ligand libraries. (2017) (0)
Crystal structure of an A-DNA dodecamer featuring an alternating pyrimidine-purine sequence (2017) (0)
A biocompatible backbone modification? - Structure and dynamics of a triazole-linked DNA duplex (2011) (0)
Towards Dark Quencher Based Real Time DNA Sequencing (2010) (0)
Addressable molecular node assembly - A generic platform of nano-scale functionalised surfaces based on a "Digitally addressable" molecular grid (2007) (0)
Synthesis of a novel dark quencher for use with long wavelength dyes in oligonucleotide probes (2003) (0)
Enrichment of Skeletal Stem Cells from Human Bone Marrow Using Spherical Nucleic Acids. (2021) (0)
Logic and Biologic Approaches (2013) (0)
Erratum: The crystal structure of d(GGATGGGAG): an essential part of the binding site for transcription factor IIIA (1986) (0)
Expanding the Chemical Repertoire of DNA Nanomaterials Generated by Rolling Circle Amplification (2020) (0)
Stable DNA triple helix formation (2009) (0)
thesis of cyclic single-stranded DNA constructs containing a single triazole , amide or phosphoramidate backbone linkage and their use as templates for rolling circle ampli fi cation and nano fl ower formation † (2018) (0)
Targeted sensing and drug delivery using smart nanoparticles (2017) (0)
Crystal structure of an unmodified A-DNA dodecamer containing 3 consecutive CpG steps (2017) (0)
A New Base‐Stable Linker for Solid‐Phase Oligonucleotide Synthesis. (1989) (0)
First Synthesis of 1-Deazacytidine, the C-Nucleoside Analogue of Cytidine. (2002) (0)
Chirality transmission in macromolecular domains (2022) (0)
Synthesis of a Modified Thymidine Monomer for Site‐Specific Incorporation of Reporter Groups into Oligonucleotides. (2001) (0)
PURINES, PYRIMIDINES AND IMIDAZOLES. PART 53. SYNTHESIS OF SOME 5-HALO ANALOGS OF METIAMIDE AND CIMETIDINE (1981) (0)
THE CRYSTAL STRUCTURE OF N(α)-TERT-BUTOXYCARBONYL-N(Π)-BENZYLOXYMETHYL-L-HISTIDINE (1983) (0)
Author response: CRISPRi is not strand-specific at all loci and redefines the transcriptional landscape (2017) (0)
Communications RNA – Protein Complexes (2013) (0)
Addressable molecular node assembly--high information density DNA nanostructures. (2008) (0)
DNA.RNA HYBRID DUPLEX CONTAINING A 5-PROPYNE DNA STRAND AND PURINE-RICH RNA STRAND, NMR, 4 STRUCTURES (2003) (0)
Explorer TYROSINE-27 OF THE SPECIFICITY POLYPEPTIDE OF ECOKI CAN BE UV CROSS-LINKED TO A BROMODEOXYURIDINE-SUBSTITUTED DNA TARGET SEQUENCE (2017) (0)
Discrimination against the Fluorescent Cytosine Analog tC by Escherichia coli DNA Polymerase IV DinB (2011) (0)
Improved Synthesis of 5-Hydroxymethyl-2′-deoxycytidine Phosphoramidite Using a 2′-Deoxyuridine to 2′-Deoxycytidine Conversion Without Temporary Protecting Groups. (2011) (0)
PNA HyBeacons for analysis of human mutations related to statin-induced myopathy (2011) (0)
DNA Duplexes Stabilized by Modified Monomer Residues: Synthesis and Stability. (1998) (0)
Ultra High Resolution Dickerson-Drew dodecamer B-DNA with 5-Hydroxymethyl-cytosine Modification (2013) (0)
A new phosphoramidite enables orthogonal double labelling to form combination oligonucleotide probes. (2022) (0)
Crystal structure of an A-DNA dodecamer containing 5-bromouracil (2017) (0)
Hybridization probe and method for quickly detecting and fast discrimination of sequences (2001) (0)
1 CRISPRi is not strand-specific and redefines the transcriptional 1 landscape 2 3 (2017) (0)
The solution structure of a DNA·RNA duplex containing 5-propynyl U and C; comparison with 5-Me modiﬁcations (0)
Crystal structure of an unmodified, self-complementary dodecamer. (2017) (0)
Crystal structure of an A-DNA dodecamer containing 5-formylcytosine in 3 consecutive CpG steps (2017) (0)
Substrate specificity of Escherichia coli damage bypass DNA polymerase IV DinB (2011) (0)
Intercalated quenchers (acridine). Dual-labelled probes (2001) (0)
Chemical modification and patterning of Si(100) using interference photolithography (2003) (0)
New two dimensional liquid-phase colorimetric assay based on old iodine-starch complexation for simple , low-cost , portable , naked-eye detection and quantification of analytes (2016) (0)
RPA activates XPF-ERCC1 to initiate the processing of DNA (2017) (0)
Dark quencher (non-fluorescent absorbing labels). Novel fluorescence-absorbing compounds (2001) (0)
Click DNA and RNA ligation for new biocompatible nucleic acid backbone mimics (2011) (0)
Synthesis of large spherical and anisotropic gold nanoparticle dimers using a seeded-growth method (2017) (0)
A membrane anchored DNA-based energy/electron transfer assembly. (2008) (0)
A novel, linear dual-labelled fluorescent probe for nucleic acid sequence analysis (2003) (0)
The stability and conformation of duplex DNA containing the novel anti-HIV drug ADRT. (1996) (0)
Initial DNA Interactions of the Binuclear Threading Intercalator L,L-[m- bidppz ACHTUNGTRENNUNG(bipy)4Ru2]4+ : An NMR Study with [d(CGCGAATTCGCG)]2** (2013) (0)
Targeted detection of mRNA biomarkers using graphene oxide and upconversion nanoparticles (2017) (0)
RNA DUPLEX CONTAINING A PURINE-RICH STRAND, NMR, 10 STRUCTURES (1998) (0)
Seeded-growth method applied to the synthesis of large spherical and anisotropic gold nanoparticle dimers (2017) (0)
The role of chemistry in the success of oligonucleotides as therapeutics (2022) (0)
Multiplex functions of DNA functionalized gold nanoparticles (2018) (0)
The Mechanical Properties of Fibrin Fibers (2013) (0)
DNA/RNA HYBRID DUPLEX CONTAINING A PURINE-RICH DNA STRAND, NMR, 10 STRUCTURES (1998) (0)
Micro/submicro-patterning of DNA on Si(100) surface (2003) (0)
PURINES, PYRIMIDINES, AND IMIDAZOLES. PART 51. NEW SYNTHESES OF SOME 5-ALKYL- - AND 5-DIALKYLAMINOIMIDAZOLES. 3-ALKYLIMIDAZOLIUM NUCLEOSIDES AND 3-ALKYLPURINES (1980) (0)
BRiEF : FREtmatrix – a MEthOD FOR siMULatiON aND aNaLysis OF FREt iN OLigOs (2014) (0)
Elongation amplification and sequencing using a chimeric oligonucleotide (1994) (0)
Hybridization probe and method for rapid detection and quick differentiation of sequences (2001) (0)
NMR Structure Analysis of the B-DNA Dodecamer CTCtCACGTGGAG with a tricyclic cytosin base analogue (2004) (0)
Base-Pair Mismatch in DNA at 2.3A Resolution (1985) (0)
Photonic generation of DNA micropatterns for haplotype analysis (2005) (0)
Balise d'hybridation et methode de detection et discrimination rapides de sequences (2001) (0)
Hybridisation beacon and method of rapid detection and sequence discrimination. (2001) (0)
Nano-Fabrication Yields . Hybridization and Click-Fixation of Polycyclic DNA Nano-Assemblies (2012) (0)
Hydridiseringsbeacon and method for the rapid sequence detection and discrimination (2001) (0)
Two step probe synthesis and multi-strand hybridisation complexes for economical nucleic acid testing (2016) (0)
MLPA-based point mutation analysis of the FBN1 gene in Marfan syndrome patients (2004) (0)
Polymerase Chain Reaction: Theory and Technology (2019) (0)
Two-Step Validation Approach for Tools to Study the DNA Repair Enzyme SNM1A. (2023) (0)
Homogenous Fluorescent Chemistries for Real-time PCR (2019) (0)
Learning from fluorescence decay dynamics: A better read out from the spectroscopic ruler (2011) (0)
Crystal Structure of a MUG-DNA pseudo substrate complex (2002) (0)
Very-short-patch DNA repair endonuclease bound to its reaction product site (2003) (0)
Cut-and-join operators and N = 4 super Yang-Mills (2010) (0)
Ja n 20 08 QMUL-PH-08-02 Permutations and the Loop (2009) (0)
Cut-and-join operators and [FORMULA] super Yang-Mills (2010) (0)
Crystal structure of an A-DNA dodecamer containing the GGGCCC motif (2017) (0)
Synthesis, oligonucleotide incorporation and fluorescence properties in DNA of a bicyclic thymine analogue (2018) (0)
An 111 In-labelled bis-ruthenium( II ) dipyridophenazine theranostic complex: mismatch DNA binding and selective radiotoxicity towards MMR-de ﬁ cient cancer cells † (2020) (0)
8 5-(1-propargylamino)-2 ′ -deoxyuridine (U P ): a novel thymidine analogue for generating DNA triplexes with increased (1999) (0)
Pentacyclic adenine: a versatile and exceptionally bright ﬂ uorescent DNA base analogue † ChemicalScience EDGE (2018) (0)
Correction to “Photogeneration of Spin Quintet Triplet–Triplet Excitations in DNA-Assembled Pentacene Stacks” (2023) (0)
Gene assembly via one-pot chemical ligation of DNA promoted by DNA nanostructures ChemComm (2018) (0)
Optical Mie Scattering by DNA-Assembled Three-Dimensional Gold Nanoparticle Superlattice Crystals (2022) (0)
An artificial triazole backbone linkage provides a split-and-click strategy to bioactive chemically modified CRISPR sgRNA (2019) (0)
Enrichment of Skeletal Stem Cells from Human Bone Marrow Using Spherical Nucleic Acids (2019) (0)
Producing the first functioning synthetic DNA using click chemistry (2020) (0)

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