Torsten Pietsch
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(Suggest an Edit or Addition)Torsten Pietsch's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- DNA methylation-based classification of central nervous system tumours (2018) (1461)
- Negative Feedback Loop of Wnt Signaling through Upregulation of Conductin/Axin2 in Colorectal and Liver Tumors (2002) (1082)
- Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas (2012) (855)
- EXTENT OF RESECTION AND SURVIVAL IN GLIOBLASTOMA MULTIFORME: IDENTIFICATION OF AND ADJUSTMENT FOR BIAS (2008) (836)
- Long-term survival with glioblastoma multiforme. (2007) (812)
- Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups. (2015) (782)
- NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide. (2009) (779)
- Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial. (2014) (744)
- Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas (2010) (714)
- Integrated Genomics Identifies Five Medulloblastoma Subtypes with Distinct Genetic Profiles, Pathway Signatures and Clinicopathological Features (2008) (682)
- New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs (2016) (608)
- Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network. (2009) (561)
- Treatment of early childhood medulloblastoma by postoperative chemotherapy alone. (2005) (515)
- International Society of Neuropathology‐Haarlem Consensus Guidelines for Nervous System Tumor Classification and Grading (2014) (514)
- Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma (2014) (496)
- NeuN: a useful neuronal marker for diagnostic histopathology. (1996) (482)
- High-dose methotrexate with or without whole brain radiotherapy for primary CNS lymphoma (G-PCNSL-SG-1): a phase 3, randomised, non-inferiority trial. (2010) (476)
- BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas. (2008) (456)
- Risk stratification of childhood medulloblastoma in the molecular era: the current consensus (2016) (406)
- Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched. (1997) (397)
- Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes. (2016) (374)
- Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing (2014) (362)
- Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma. (2013) (362)
- Polyclonal Evolution of Multiple Secondary KIT Mutations in Gastrointestinal Stromal Tumors under Treatment with Imatinib Mesylate (2006) (351)
- Phase I/IIa study of cilengitide and temozolomide with concomitant radiotherapy followed by cilengitide and temozolomide maintenance therapy in patients with newly diagnosed glioblastoma. (2010) (338)
- cIMPACT‐NOW update 6: new entity and diagnostic principle recommendations of the cIMPACT‐Utrecht meeting on future CNS tumor classification and grading (2020) (293)
- Lomustine-temozolomide combination therapy versus standard temozolomide therapy in patients with newly diagnosed glioblastoma with methylated MGMT promoter (CeTeG/NOA–09): a randomised, open-label, phase 3 trial (2019) (275)
- Divergent clonal selection dominates medulloblastoma at recurrence (2016) (266)
- Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas (2011) (264)
- Survival and prognostic factors of early childhood medulloblastoma: an international meta-analysis. (2010) (251)
- Hyperfractionated versus conventional radiotherapy followed by chemotherapy in standard-risk medulloblastoma: results from the randomized multicenter HIT-SIOP PNET 4 trial. (2012) (247)
- Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome- and transcriptome-wide profiling improves stratification of prognostically distinct patient groups (2015) (245)
- Deletions of AXIN1, a component of the WNT/wingless pathway, in sporadic medulloblastomas. (2001) (236)
- Predictive impact of MGMT promoter methylation in glioblastoma of the elderly (2012) (234)
- Deletion of Trp‐557 and Lys‐558 in the juxtamembrane domain of the c‐kit protooncogene is associated with metastatic behavior of gastrointestinal stromal tumors (2003) (230)
- Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays (2013) (230)
- Histopathological grading of pediatric ependymoma: reproducibility and clinical relevance in European trial cohorts (2011) (216)
- Optimization of quantitative MGMT promoter methylation analysis using pyrosequencing and combined bisulfite restriction analysis. (2007) (213)
- Molecular genetic analysis of ependymal tumors. NF2 mutations and chromosome 22q loss occur preferentially in intramedullary spinal ependymomas. (1999) (212)
- Molecular profiling identifies prognostic subgroups of pediatric glioblastoma and shows increased YB-1 expression in tumors. (2007) (209)
- Isolation and characterization of human patched 2 (PTCH2), a putative tumour suppressor gene inbasal cell carcinoma and medulloblastoma on chromosome 1p32. (1999) (206)
- Post-operative hypothalamic lesions and obesity in childhood craniopharyngioma: results of the multinational prospective trial KRANIOPHARYNGEOM 2000 after 3-year follow-up. (2011) (202)
- Long-term follow-up of the multicenter, multidisciplinary treatment study HIT-LGG-1996 for low-grade glioma in children and adolescents of the German Speaking Society of Pediatric Oncology and Hematology. (2012) (201)
- Betulinic acid: A new cytotoxic agent against malignant brain‐tumor cells (1999) (201)
- Expression and distribution of vascular endothelial growth factor protein in human brain tumors (1997) (186)
- Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries. (2018) (184)
- Long-term analysis of the NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with PCV or temozolomide. (2015) (183)
- Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma (2014) (180)
- Long-term outcome and clinical prognostic factors in children with medulloblastoma treated in the prospective randomised multicentre trial HIT'91. (2009) (174)
- C‐MYC expression in medulloblastoma and its prognostic value (2000) (173)
- Molecular Markers in Low-Grade Gliomas: Predictive or Prognostic? (2011) (171)
- Somatic mutations of WNT/wingless signaling pathway components in primitive neuroectodermal tumors (2001) (165)
- Embryonal tumor with abundant neuropil and true rosettes (ETANTR), ependymoblastoma, and medulloepithelioma share molecular similarity and comprise a single clinicopathological entity (2013) (165)
- Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors. (2016) (165)
- Association of platelet-derived growth factor receptor alpha mutations with gastric primary site and epithelioid or mixed cell morphology in gastrointestinal stromal tumors. (2004) (163)
- Diffuse high-grade gliomas with H3 K27M mutations carry a dismal prognosis independent of tumor location (2018) (159)
- The CD34 epitope is expressed in neoplastic and malformative lesions associated with chronic, focal epilepsies (1999) (159)
- Combined postoperative irradiation and chemotherapy for anaplastic ependymomas in childhood: results of the German prospective trials HIT 88/89 and HIT 91. (2000) (157)
- A randomised, open label phase III trial with nimotuzumab, an anti-epidermal growth factor receptor monoclonal antibody in the treatment of newly diagnosed adult glioblastoma. (2015) (157)
- Long-Term Survival in Primary Glioblastoma With Versus Without Isocitrate Dehydrogenase Mutations (2013) (152)
- Elevated Expression of Wnt Antagonists Is a Common Event in Hepatoblastomas (2005) (148)
- Phosphatidylinositol 3′-Kinase/AKT Signaling Is Activated in Medulloblastoma Cell Proliferation and Is Associated with Reduced Expression of PTEN (2006) (147)
- Treatment of young children with localized medulloblastoma by chemotherapy alone: results of the prospective, multicenter trial HIT 2000 confirming the prognostic impact of histology. (2011) (146)
- Treatment of early childhood medulloblastoma by postoperative chemotherapy and deferred radiotherapy. (2009) (144)
- Overexpression of Human Dickkopf-1, an Antagonist of wingless/WNT Signaling, in Human Hepatoblastomas and Wilms’ Tumors (2003) (142)
- Effects of human stem cell factor (c-kit ligand) on proliferation of myeloid leukemia cells: heterogeneity in response and synergy with other hematopoietic growth factors. (1992) (141)
- Bevacizumab Plus Irinotecan Versus Temozolomide in Newly Diagnosed O6-Methylguanine-DNA Methyltransferase Nonmethylated Glioblastoma: The Randomized GLARIUS Trial. (2016) (140)
- Activation of the CD95 (APO-1/Fas) pathway in drug- and γ-irradiation-induced apoptosis of brain tumor cells (1998) (136)
- Comprehensive genomic analysis of desmoplastic medulloblastomas: identification of novel amplified genes and separate evaluation of the different histological components (2006) (136)
- Molecular, Pathological, Radiological, and Immune Profiling of Non-brainstem Pediatric High-Grade Glioma from the HERBY Phase II Randomized Trial (2018) (131)
- Anticancer Effects of Niclosamide in Human Glioblastoma (2013) (130)
- Combined 1p/19q Loss in Oligodendroglial Tumors: Predictive or Prognostic Biomarker? (2007) (130)
- Increased serum levels of granulocyte colony-stimulating factor in patients with severe congenital neutropenia. (1991) (129)
- Focal genomic amplification at 19q13.42 comprises a powerful diagnostic marker for embryonal tumors with ependymoblastic rosettes (2010) (128)
- Perilesional neurochemical changes in focal epilepsies (1996) (127)
- Dual Blockade of the PI3K/AKT/mTOR (AZD8055) and RAS/MEK/ERK (AZD6244) Pathways Synergistically Inhibits Rhabdomyosarcoma Cell Growth In Vitro and In Vivo (2013) (124)
- Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort (2014) (120)
- Insulin-like growth factor II is involved in the proliferation control of medulloblastoma and its cerebellar precursor cells. (2005) (120)
- Intensive chemotherapy improves survival in pediatric high‐grade glioma after gross total resection: results of the HIT‐GBM‐C protocol (2010) (120)
- Surgery for Spinal Cord Ependymomas: Outcome and Prognostic Factors (2011) (120)
- Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis. (2015) (119)
- Role of radiotherapy in the treatment of supratentorial primitive neuroectodermal tumors in childhood: results of the prospective German brain tumor trials HIT 88/89 and 91. (2002) (118)
- Molecular genetic analysis of malignant melanomas for aberrations of the WNT signaling pathway genes CTNNB1, APC, ICAT and BTRC (2002) (118)
- Beta‐catenin accumulation in the progression of human hepatocarcinogenesis correlates with loss of E‐cadherin and accumulation of p53, but not with expression of conventional WNT‐1 target genes (2003) (118)
- Frequency, Risk‐Factors and Survival of Children With Atypical Teratoid Rhabdoid Tumors (AT/RT) of the CNS Diagnosed between 1988 and 2004, and Registered to the German HIT Database (2011) (118)
- Molecular characterization of long‐term survivors of glioblastoma using genome‐ and transcriptome‐wide profiling (2014) (117)
- Medulloblastoma Variants: Age-Dependent Occurrence and Relation to Gorlin Syndrome—A New Clinical Perspective (2009) (116)
- Amplification and overexpression of the IGF2 regulator PLAG1 in hepatoblastoma (2004) (115)
- Residual tumor cells are unique cellular targets in glioblastoma (2010) (115)
- Outcome of patients with intracranial non-germinomatous germ cell tumors—lessons from the SIOP-CNS-GCT-96 trial (2017) (115)
- Infant high grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes. (2020) (115)
- Epidermal Growth Factor Receptor Variant III (EGFRvIII) Positivity in EGFR-Amplified Glioblastomas: Prognostic Role and Comparison between Primary and Recurrent Tumors (2017) (114)
- H3F3A K27M mutation in pediatric CNS tumors: a marker for diffuse high-grade astrocytomas. (2013) (113)
- Loss of maternal alleles on chromosome arm 11p in hepatoblastoma. (1994) (112)
- c-kit Mutations in Gastrointestinal Stromal Tumors Occur Preferentially in the Spindle Rather Than in the Epithelioid Cell Variant (2002) (112)
- Should children at risk for familial adenomatous polyposis be screened for hepatoblastoma and children with apparently sporadic hepatoblastoma be screened for APC germline mutations? (2006) (109)
- Medulloblastoma Down Under 2013: a report from the third annual meeting of the International Medulloblastoma Working Group (2013) (109)
- Expression of the Ets-1 transcription factor in human astrocytomas is associated with Fms-like tyrosine kinase-1 (Flt-1)/vascular endothelial growth factor receptor-1 synthesis and neoangiogenesis. (1999) (107)
- Specific detection of methionine 27 mutation in histone 3 variants (H3K27M) in fixed tissue from high-grade astrocytomas (2014) (106)
- Nuclear exclusion of TET1 is associated with loss of 5-hydroxymethylcytosine in IDH1 wild-type gliomas. (2012) (102)
- Treatment of Children and Adolescents With Metastatic Medulloblastoma and Prognostic Relevance of Clinical and Biologic Parameters. (2016) (102)
- Prognostic Relevance of Clinical and Biological Risk Factors in Childhood Medulloblastoma: Results of Patients Treated in the Prospective Multicenter Trial HIT'91 (2007) (101)
- Molecularly defined diffuse leptomeningeal glioneuronal tumor (DLGNT) comprises two subgroups with distinct clinical and genetic features (2018) (101)
- Atypical choroid plexus papilloma: clinical experience in the CPT-SIOP-2000 study (2009) (101)
- Supratentorial ependymomas of childhood carry C11orf95–RELA fusions leading to pathological activation of the NF-κB signaling pathway (2014) (100)
- Plasma levels of macrophage migration inhibitory factor are elevated in patients with severe sepsis (2001) (100)
- A highly conserved processed PTEN pseudogene is located on chromosome band 9p21 (1998) (99)
- Glioneuronal Malformative Lesions and Dysembryoplastic Neuroepithelial Tumors in Pateints with Chroninc Pharmacoresistant Epilepsies (1995) (98)
- Clinical and molecular features in patients with atypical teratoid rhabdoid tumor or malignant rhabdoid tumor (2010) (96)
- Assessment and prognostic significance of the epidermal growth factor receptor vIII mutation in glioblastoma patients treated with concurrent and adjuvant temozolomide radiochemotherapy (2014) (95)
- Expression of the Neurotrophin Receptor p75NTR in Medulloblastomas Is Correlated with Distinct Histological and Clinical Features: Evidence for a Medulloblastoma Subtype Derived from the External Granule Cell Layer (2000) (95)
- Hepatic stem‐like cells in hepatoblastoma: expression of cytokeratin 7, albumin and oval cell associated antigens detected by OV‐1 and OV‐6 (1997) (94)
- Expression of stem-cell factor and its receptor c-kit protein in normal testicular tissue and malignant germ-cell tumours (2005) (93)
- Epigenetic Silencing of the Protocadherin Family Member PCDH-γ-All in Astrocytomas (2005) (92)
- Low Frequency of SV40, JC and BK Polyomavirus Sequences in Human Medulloblastomas, Meningiomas and Ependymomas (2000) (91)
- A European randomised controlled trial of the addition of etoposide to standard vincristine and carboplatin induction as part of an 18-month treatment programme for childhood (≤16 years) low grade glioma – A final report (2017) (89)
- Xanthogranuloma, Rathke's cyst, and childhood craniopharyngioma: results of prospective multinational studies of children and adolescents with rare sellar malformations. (2012) (89)
- A European randomised controlled trial of the addition of etoposide to standard vincristine and carboplatin induction as part of an 18-month treatment programme for childhood (≤16 years) low grade glioma – A final report (2017) (89)
- Randomized phase III study of whole-brain radiotherapy for primary CNS lymphoma (2015) (87)
- Neural antigens in oligodendrogliomas and dysembryoplastic neuroepithelial tumors (1997) (83)
- OTX1 and OTX2 Expression Correlates With the Clinicopathologic Classification of Medulloblastomas (2006) (82)
- CT and MR imaging in atypical teratoid/rhabdoid tumors of the central nervous system (2008) (82)
- Relapse patterns and outcome after relapse in standard risk medulloblastoma: a report from the HIT-SIOP-PNET4 study (2016) (81)
- Sonic hedgehog-associated medulloblastoma arising from the cochlear nuclei of the brainstem (2012) (81)
- Atypical Teratoid/Rhabdoid Tumors and Choroid Plexus Tumors: When Genetics “Surprise” Pathology (2003) (81)
- Treatment of adult nonmetastatic medulloblastoma patients according to the paediatric HIT 2000 protocol: a prospective observational multicentre study. (2013) (81)
- Role of radiotherapy in supratentorial primitive neuroectodermal tumor in young children: results of the German HIT-SKK87 and HIT-SKK92 trials. (2006) (81)
- RNOP-09: Pegylated liposomal doxorubicine and prolonged temozolomide in addition to radiotherapy in newly diagnosed glioblastoma - a phase II study (2009) (80)
- Microsatellite analysis of loss of heterozygosity on chromosomes 9q, 11 p and 17p in medulloblastomas (1994) (79)
- In vivo inhibition of angiogenesis and growth of the human U-87 malignant glial tumor by treatment with an antibody against basic fibroblast growth factor. (1995) (79)
- Analysis of β-Catenin Gene Mutations in Pancreatic Tumors (1999) (79)
- Characterization of five new cell lines derived from human primitive neuroectodermal tumors of the central nervous system. (1994) (78)
- Analyses of Treatment Variables for Patients with Childhood Craniopharyngioma – Results of the Multicenter Prospective Trial KRANIOPHARYNGEOM 2000 after Three Years of Follow-Up (2008) (78)
- Epigenetic downregulation of mitogen-activated protein kinase phosphatase MKP-2 relieves its growth suppressive activity in glioma cells. (2010) (77)
- High frequency of H3F3AK27M mutations characterizes pediatric and adult high-grade gliomas of the spinal cord (2015) (74)
- Antitumoral Effects of Calcitriol in Basal Cell Carcinomas Involve Inhibition of Hedgehog Signaling and Induction of Vitamin D Receptor Signaling and Differentiation (2011) (74)
- Epigenetic silencing of the protocadherin family member PCDH-gamma-A11 in astrocytomas. (2005) (73)
- Natural history and management of low-grade glioma in NF-1 children (2010) (73)
- Evidence of H3 K27M mutations in posterior fossa ependymomas (2016) (73)
- Epigenetic Silencing of the HIC‐1 Gene in Human Medulloblastomas (2003) (73)
- FGFR1 mutations in Rosette-forming glioneuronal tumors of the fourth ventricle. (2014) (72)
- Activation of Phosphatidylinositol-3′-kinase/AKT Signaling Is Essential in Hepatoblastoma Survival (2009) (71)
- The Molecular Landscape of ETMR at Diagnosis and Relapse (2019) (70)
- Treatment of young children with CNS-primitive neuroectodermal tumors/pineoblastomas in the prospective multicenter trial HIT 2000 using different chemotherapy regimens and radiotherapy. (2013) (69)
- Analysis of HIC‐1 methylation and transcription in human ependymomas (2004) (68)
- Hepatocyte growth‐factor‐scatter factor can stimulate post‐operative tumor‐cell proliferation in childhood hepatoblastoma (2000) (67)
- Novel ERBB4 juxtamembrane splice variants are frequently expressed in childhood medulloblastoma (2001) (67)
- Genomic Alterations of Adamantinomatous and Papillary Craniopharyngioma (2017) (67)
- Large cell/anaplastic medulloblastoma: Outcome according to myc status, histopathological, and clinical risk factors (2010) (67)
- Expression of receptors for granulocyte colony-stimulating factor on neutrophils from patients with severe congenital neutropenia and cyclic neutropenia. (1992) (66)
- Thalamic high-grade gliomas in children: a distinct clinical subset? (2011) (65)
- Heterogeneous regional expression patterns of matrix metalloproteinases in human malignant gliomas (1999) (62)
- Neurochemical Profile of Glioneuronal Lesions from Patients with Pharmacoresistant Focal Epilepsies (1995) (61)
- H3.3 G34R mutations in pediatric primitive neuroectodermal tumors of central nervous system (CNS-PNET) and pediatric glioblastomas: possible diagnostic and therapeutic implications? (2013) (61)
- Mutations of the Wnt antagonist AXIN2 (Conductin) result in TCF‐dependent transcription in medulloblastomas (2007) (61)
- High Expression of Somatostatin Receptor Subtype 2 (sst2) in Medulloblastoma: Implications for Diagnosis and Therapy (1999) (60)
- Aberrant hypermethylation of the major breakpoint cluster region in 17p11.2 in medulloblastomas but not supratentorial PNETs (2001) (60)
- Subtype‐specific expression and genetic alterations of the chemokinereceptor gene CXCR4 in medulloblastomas (2005) (60)
- Supratentorial clear cell ependymomas with branching capillaries demonstrate characteristic clinicopathological features and pathological activation of nuclear factor-kappaB signaling. (2016) (60)
- Childhood supratentorial ependymomas with YAP1‐MAMLD1 fusion: an entity with characteristic clinical, radiological, cytogenetic and histopathological features (2018) (60)
- A pyrosequencing-based assay for the rapid detection of IDH1 mutations in clinical samples. (2010) (59)
- High-dose chemotherapy (HDCT) with auto-SCT in children with atypical teratoid/rhabdoid tumors (AT/RT): a report from the European Rhabdoid Registry (EU-RHAB) (2014) (59)
- Valproic Acid Prolongs Survival Time of Severe Combined Immunodeficient Mice Bearing Intracerebellar Orthotopic Medulloblastoma Xenografts (2006) (59)
- Mutations and elevated transcriptional activity of conductin (AXIN2) in hepatoblastomas (2004) (58)
- Insulin‐like growth factor‐1 receptor acts as a growth regulator in synovial sarcoma (2008) (58)
- Indications for a tumor suppressor gene at 22q11 involved in the pathogenesis of ependymal tumors and distinct from hSNF5/INI1 (2001) (58)
- Mutational and Expression Analysis of the NF1 Gene Argues Against a Role as Tumor Suppressor in Sporadic Pilocytic Astrocytomas (2002) (57)
- Ependymoma of the spinal cord in children and adolescents: a retrospective series from the HIT database. (2010) (56)
- Vascular Endothelial Growth Factor (VEGF) in Astrocytic Gliomas – A Prognostic Factor? (2004) (56)
- Molecular pathogenesis of childhood brain tumors (2004) (55)
- Transcranial electro-hyperthermia combined with alkylating chemotherapy in patients with relapsed high-grade gliomas: phase I clinical results (2010) (55)
- Expression of coronin‐3 (coronin‐1C) in diffuse gliomas is related to malignancy (2007) (55)
- Targeted next generation sequencing reveals unique mutation profile of primary melanocytic tumors of the central nervous system (2016) (55)
- Childhood Craniopharyngioma – Changes of Treatment Strategies in the Trials KRANIOPHARYNGEOM 2000/2007 (2014) (54)
- Expression of podoplanin in human astrocytic brain tumors is controlled by the PI3K-AKT-AP-1 signaling pathway and promoter methylation. (2012) (54)
- Differential control of VEGF synthesis and secretion in human glioma cells by IL-1 and EGF (1999) (53)
- Update on the integrated histopathological and genetic classification of medulloblastoma – a practical diagnostic guideline (2016) (53)
- Childhood pineoblastoma: experiences from the prospective multicenter trials HIT-SKK87, HIT-SKK92 and HIT91 (2006) (52)
- A Rapid and Sensitive Protocol for Competitive Reverse Transcriptase (cRT) PCR Analysis of Cellular Genes (1998) (52)
- Biomarker-driven stratification of disease-risk in non-metastatic medulloblastoma: Results from the multi-center HIT-SIOP-PNET4 clinical trial (2015) (52)
- Expression of the c‐Kit receptor and its ligand SCF in non‐small‐cell lung carcinomas (1998) (51)
- Subgroup-specific localization of human medulloblastoma based on pre-operative MRI (2014) (51)
- Valproic acid was well tolerated in heavily pretreated pediatric patients with high-grade glioma (2008) (51)
- Diagnostic value of markers M2A, OCT3/4, AP‐2γ, PLAP and c‐KIT in the detection of extragonadal seminomas (2006) (50)
- Longitudinal heterogeneity in glioblastoma: moving targets in recurrent versus primary tumors (2019) (49)
- Betulinic acid: a new chemotherapeutic agent in the treatment of neuroectodermal tumors. (1999) (49)
- Prognostic effect of whole chromosomal aberration signatures in standard-risk, non-WNT/non-SHH medulloblastoma: a retrospective, molecular analysis of the HIT-SIOP PNET 4 trial (2018) (49)
- p57(KIP2) is not mutated in hepatoblastoma but shows increased transcriptional activity in a comparative analysis of the three imprinted genes p57(KIP2), IGF2, and H19. (2000) (49)
- Multicenter pilot study of radiochemotherapy as first-line treatment for adults with medulloblastoma (NOA-07) (2018) (49)
- Late and prolonged pseudoprogression in glioblastoma after treatment with lomustine and temozolomide. (2012) (48)
- Loss of heterozygosity on chromosome 1 in human hepatoblastoma (1996) (48)
- Functional Subclone Profiling for Prediction of Treatment-Induced Intratumor Population Shifts and Discovery of Rational Drug Combinations in Human Glioblastoma (2016) (48)
- Impact of chemotherapy on disseminated low‐grade glioma in children and adolescents: Report from the HIT‐LGG 1996 trial (2011) (48)
- Subpopulations of malignant gliomas in pediatric patients: analysis of the HIT-GBM database (2008) (48)
- Limited role for extended maintenance temozolomide for newly diagnosed glioblastoma (2017) (47)
- SIOP-E-BTG and GPOH Guidelines for Diagnosis and Treatment of Children and Adolescents with Low Grade Glioma (2019) (46)
- Aberrant methylation and reduced expression of LHX9 in malignant gliomas of childhood. (2009) (46)
- Molecular stratification of medulloblastoma: comparison of histological and genetic methods to detect Wnt activated tumours (2015) (46)
- Expression of Different Extracellular Matrix Components in Human Brain Tumor and Melanoma Cells in Respect to Variant Culture Conditions (1999) (45)
- Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroups. (2016) (45)
- Anaplastic ganglioglioma in children (2009) (44)
- No evidence for the H133Y mutation in SONIC HEDGEHOG in a collection of common tumour types (1998) (43)
- Blood mononuclear cells from patients with severe congenital neutropenia are capable of producing granulocyte colony-stimulating factor. (1991) (43)
- Disseminated oligodendroglial cell-like leptomeningeal tumors: preliminary diagnostic and therapeutic results for a novel tumor entity (2015) (43)
- Diagnostics of pediatric supratentorial RELA ependymomas: integration of information from histopathology, genetics, DNA methylation and imaging (2018) (43)
- Microsatellite Instability in Pediatric and Adult High‐grade Gliomas (2007) (42)
- WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma (2014) (42)
- Epigenetic silencing of the candidate tumor suppressor gene PROX1 in sporadic breast cancer (2007) (42)
- DNA methylation-based classification of ependymomas in adulthood: implications for diagnosis and treatment (2018) (42)
- Nonmetastatic Medulloblastoma of Early Childhood: Results From the Prospective Clinical Trial HIT-2000 and An Extended Validation Cohort. (2020) (41)
- Treatment of children with central nervous system primitive neuroectodermal tumors/pinealoblastomas in the prospective multicentric trial HIT 2000 using hyperfractionated radiation therapy followed by maintenance chemotherapy. (2014) (40)
- Prognostic impact of B-cell lymphoma 6 in primary CNS lymphoma. (2015) (40)
- Coexpression of stem cell factor and its receptor c-Kit in human malignant glioma cell lines (2004) (39)
- EANO-EURACAN clinical practice guideline for diagnosis, treatment, and follow-up of post-pubertal and adult patients with medulloblastoma. (2019) (39)
- Epigenetic silencing of the candidate tumor suppressor gene PROX1 in sporadic breast cancer. (2005) (38)
- HGNET-BCOR Tumors of the Cerebellum: Clinicopathologic and Molecular Characterization of 3 Cases (2017) (38)
- High dose methotrexate for pediatric high grade glioma: results of the HIT-GBM-D Pilot study (2011) (37)
- LONG-TERM EFFICACY AND TOXICITY OF BEVACIZUMAB-BASED THERAPY IN CHILDREN WITH RECURRENT LOW-GRADE GLIOMAS (2012) (37)
- Spinal cord injury-induced expression of the immune-regulatory chemokine interleukin-16 caused by activated microglia/macrophages and CD8+ cells. (2006) (37)
- Production of interleukin‐1β and interleukin‐6 in hepatoblastoma (1993) (36)
- Analysis of beta-catenin gene mutations in pancreatic tumors. (1999) (36)
- Variable Imprinting of H19 and IGF2 in Fetal Cerebellum and Medulloblastoma (1996) (36)
- Dolastatin 10 and dolastatin 15: effects of two natural peptides on growth and differentiation of leukemia cells. (1992) (36)
- Extramedullary erythropoiesis in human liver grafts (1995) (36)
- Germline GPR161 Mutations Predispose to Pediatric Medulloblastoma (2019) (36)
- Spinal Cord Ependymomas With MYCN Amplification Show Aggressive Clinical Behavior. (2019) (35)
- Evaluation of age-dependent treatment strategies for children and young adults with pineoblastoma: analysis of pooled European Society for Paediatric Oncology (SIOP-E) and US Head Start data (2016) (35)
- Expression of variant CD44 epitopes in human astrocytic brain tumors (1995) (35)
- Pediatric high grade glioma of the spinal cord: results of the HIT-GBM database (2012) (34)
- Molecular analysis of the lissencephaly gene 1 (LIS‐1) in medulloblastomas (1996) (34)
- Analysis of the max‐binding protein MNT in human medulloblastomas (1999) (34)
- Loss of heterozygosity at locus F13B on chromosome 1q in human medulloblastoma (1996) (34)
- Brainstem biopsy in pediatric diffuse intrinsic pontine glioma in the era of precision medicine: the INFORM study experience. (2019) (34)
- Extramedullary Hematopoiesis and Intratumoral Production of Cytokines in Childhood Hepatoblastoma (1995) (34)
- Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours (2012) (33)
- Diffuse glioneuronal tumour with oligodendroglioma‐like features and nuclear clusters (DGONC) – a molecularly defined glioneuronal CNS tumour class displaying recurrent monosomy 14 (2019) (33)
- CNS embryonal tumours: WHO 2016 and beyond (2018) (33)
- P-glycoprotein modulation improves in vitro chemosensitivity in malignant pediatric liver tumors. (2003) (33)
- Expression pattern of galectin‐3 in neural tumor cell lines (2000) (32)
- Subcutaneous and intrahepatic growth of human hepatoblastoma in immunodeficient mice. (2006) (32)
- Immunolocalization of granulocyte‐colony‐stimulating factor in human glial and primitive neuroectodermal tumors (1994) (32)
- SGNE1/7B2 is epigenetically altered and transcriptionally downregulated in human medulloblastomas (2007) (32)
- Strategies to improve the quality of survival for childhood brain tumour survivors. (2015) (31)
- Papillary glioneuronal tumor (PGNT) exhibits a characteristic methylation profile and fusions involving PRKCA (2019) (31)
- Children <1 year show an inferior outcome when treated according to the traditional LGG treatment strategy: A report from the german multicenter trial HIT‐LGG 1996 for children with low grade glioma (LGG) (2014) (31)
- Radiotherapy in pediatric pilocytic astrocytomas (2013) (31)
- Tuberous sclerosis-like lesions in epileptogenic human neocortex lack allelic loss at the TSC1 and TSC2 regions (1996) (31)
- Genome-wide DNA copy number analysis of desmoplastic infantile astrocytomas and desmoplastic infantile gangliogliomas. (2013) (31)
- Genetic Analysis of Diffuse High‐Grade Astrocytomas in Infancy Defines a Novel Molecular Entity (2015) (30)
- CNS germinomas are characterized by global demethylation, chromosomal instability and mutational activation of the Kit-, Ras/Raf/Erk- and Akt-pathways (2016) (30)
- Metastatic medulloblastoma in adults: outcome of patients treated according to the HIT2000 protocol. (2015) (30)
- PTEN mutations and activation of the PI3K/Akt/mTOR signaling pathway in papillary tumors of the pineal region. (2014) (30)
- Prognostic impact of molecular genetic alterations in hepatoblastoma. (2002) (30)
- Absence of KIAA1549-BRAF fusion in rosette-forming glioneuronal tumors of the fourth ventricle (RGNT) (2012) (30)
- Mutations in the Nijmegen Breakage Syndrome Gene in Medulloblastomas (2008) (30)
- Molecular Neuropathology of Astrocytic Brain Tumors (1997) (29)
- Activation of the basal cell carcinoma pathway in a patient with CNS HGNET-BCOR diagnosis: consequences for personalized targeted therapy (2016) (29)
- Supratentorial Primitive Neuroectodermal Tumors of the Central Nervous System in Adults: Molecular and Histopathologic Analysis of 12 Cases (2011) (29)
- Vasoactive intestinal peptide (VIP) and VIP receptors: Gene expression and growth modulation in medulloblastoma and other central primitive neuroectodermal tumors of childhood (1999) (29)
- Dominant-negative inhibition of Ets 1 suppresses tumor growth, invasion and migration in rat C6 glioma cells and reveals differentially expressed Ets 1 target genes. (2009) (29)
- p53 expression predicts dismal outcome for medulloblastoma patients with metastatic disease (2011) (29)
- Supratentorial ependymoma in childhood: more than just RELA or YAP (2021) (28)
- The PI3K inhibitor GDC-0941 displays promising in vitro and in vivo efficacy for targeted medulloblastoma therapy (2014) (28)
- Inactivation of Ets 1 transcription factor by a specific decoy strategy reduces rat C6 glioma cell proliferation and mmp-9 expression. (2005) (28)
- Allelic loss at 10q23.3 but lack of mutation of PTEN/MMAC1 in chromophobe renal cell carcinoma. (2001) (28)
- Giant Cell Glioblastoma Is Associated With Altered Aurora B Expression and Concomitant p53 Mutation (2010) (27)
- Intramedullary gangliogliomas: histopathologic and molecular features of 25 cases. (2016) (27)
- Pediatric atypical choroid plexus papilloma reconsidered: increased mitotic activity is prognostic only in older children (2015) (27)
- Combination of Hedgehog Signaling Blockage and Chemotherapy Leads to Tumor Reduction in Pancreatic Adenocarcinomas (2012) (27)
- Cerebellar location may predict an unfavourable prognosis in paediatric high-grade glioma (2013) (26)
- YAP1/TAZ drives ependymoma-like tumour formation in mice (2020) (26)
- RANK (TNFRSF11A) is epigenetically inactivated and induces apoptosis in gliomas. (2012) (25)
- Systematic comparison of MRI findings in pediatric ependymoblastoma with ependymoma and CNS primitive neuroectodermal tumor not otherwise specified. (2015) (25)
- ACTR-58. PHASE III TRIAL OF CCNU/TEMOZOLOMIDE (TMZ) COMBINATION THERAPY VS. STANDARD TMZ THERAPY FOR NEWLY DIAGNOSED MGMT-METHYLATED GLIOBLASTOMA PATIENTS: THE CeTeg/NOA-09 trial (2017) (25)
- Desmoplastic myxoid tumor, SMARCB1-mutant: clinical, histopathological and molecular characterization of a pineal region tumor encountered in adolescents and adults (2019) (25)
- Recurrence in childhood medulloblastoma (2011) (25)
- No evidence for mutations or altered expression of the Suppressor of Fused gene (SUFU) in primitive neuroectodermal tumours (2004) (25)
- Cervico‐medullary desmoplastic infantile ganglioglioma: An unusual case with diffuse leptomeningeal dissemination at diagnosis (2005) (25)
- Molecular, clinicopathological, and immune correlates of LAG3 promoter DNA methylation in melanoma (2020) (24)
- Molecular genetic studies in medulloblastomas: evidence for tumor suppressor genes at the chromosomal regions 1q31-32 and 17p13. (1997) (24)
- High-Resolution Genomic Analysis Does Not Qualify Atypical Plexus Papilloma as a Separate Entity Among Choroid Plexus Tumors (2015) (24)
- Integrated Genomic Classification of Melanocytic Tumors of the Central Nervous System Using Mutation Analysis, Copy Number Alterations, and DNA Methylation Profiling (2018) (23)
- Prognostic and predictive value of PD-L2 DNA methylation and mRNA expression in melanoma (2020) (23)
- Activating CYSLTR2 and PLCB4 Mutations in Primary Leptomeningeal Melanocytic Tumors. (2017) (23)
- Biology and grading of pleomorphic xanthoastrocytoma—what have we learned about it? (2020) (23)
- Type, Frequency, and Spatial Distribution of Immune Cell Infiltrates in CNS Germinomas: Evidence for Inflammatory and Immunosuppressive Mechanisms (2018) (23)
- Differential imaging characteristics and dissemination potential of pilomyxoid astrocytomas versus pilocytic astrocytomas (2015) (23)
- p75NTR induces apoptosis in medulloblastoma cells (2011) (23)
- Analysis of KIAA1549‐BRAF fusion status in a case of rosette‐forming glioneuronal tumor of the fourth ventricle (RGNT) (2011) (23)
- Somatic mitochondrial mutations in pilocytic astrocytoma. (2009) (22)
- Akt and mTORC1 signaling as predictive biomarkers for the EGFR antibody nimotuzumab in glioblastoma (2018) (22)
- Long-term outcome of patients with WHO Grade III and IV gliomas treated by fractionated intracavitary radioimmunotherapy. (2015) (22)
- WHO grade has no prognostic value in the pediatric high-grade glioma included in the HERBY trial (2019) (22)
- Surgical management of intracranial subependymomas (2011) (22)
- Outcome of 11 children with ependymoblastoma treated within the prospective HIT-trials between 1991 and 2006 (2011) (21)
- Clinical and epidemiological characteristics of pediatric gliosarcomas (2010) (21)
- Absence of TERT promoter mutations in primary melanocytic tumours of the central nervous system (2014) (21)
- Characterization of a continuous cell line (MHH-NB-11) derived from advanced neuroblastoma. (1988) (21)
- Rhabdoid meningioma of the tentorium with expression of desmin in a 12-year-old Turner syndrome patient (2005) (20)
- Which clinical and biological tumor markers proved predictive in the prospective multicenter trial HIT'91--implications for investigating childhood medulloblastoma. (2007) (20)
- Human medulloblastomas lack point mutations and homozygous deletions of the hSNF5/INI1 tumour suppressor gene (2002) (20)
- Developmental expression and differentiation-related neuron-specific splicing of metastasis suppressor 1 (Mtss1) in normal and transformed cerebellar cells (2007) (20)
- Improved risk-stratification for posterior fossa ependymoma of childhood considering clinical, histological and genetic features – a retrospective analysis of the HIT ependymoma trial cohort (2019) (19)
- Primary central nervous system primitive neuroectodermal tumors (CNS-PNETs) of the spinal cord in children: four cases from the German HIT database with a critical review of the literature (2011) (19)
- Pediatric giant cell glioblastoma: New insights into a rare tumor entity. (2009) (19)
- Do host factors determine long-term survival in glioblastoma? A genome/transcriptome profiling study by the German Glioma Network. (2014) (19)
- Characterization of Neural Cell Lines Derived from SV40 Large T‐Induced Primitive Neuroectodermal Tumors (1997) (19)
- PATZ1 fusions define a novel molecularly distinct neuroepithelial tumor entity with a broad histological spectrum (2021) (19)
- MRI Characteristics of Ependymoblastoma: Results from 22 Centrally Reviewed Cases (2014) (19)
- Developmental-dependent DNA methylation of the IGF2 and H19 promoters is correlated to the promoter activities in human liver development. (1998) (18)
- Minimal methylation classifier (MIMIC): A novel method for derivation and rapid diagnostic detection of disease-associated DNA methylation signatures (2017) (18)
- Allelic loss but absence of mutations in the polyspecific transporter gene BWR1A on 11p15.5 in hepatoblastoma (2004) (18)
- H3F3A-G34R mutant high grade neuroepithelial neoplasms with glial and dysplastic ganglion cell components (2019) (18)
- Promoter-specific transcription of the IGF2 gene: a novel rapid, non-radioactive and highly sensitive protocol for mRNA analysis (2001) (18)
- CDKN2A deletion in supratentorial ependymoma with RELA alteration indicates a dismal prognosis: a retrospective analysis of the HIT ependymoma trial cohort (2020) (17)
- Bone Involvement in Atypical Teratoid/Rhabdoid Tumors of the CNS (2013) (17)
- Advances in Brief Childhood Hepatoblastomas Frequently Carry a Mutated Degradation Targeting Box of the b-Catenin Gene 1 (1999) (17)
- Paracrine and autocrine growth mechanisms of human stem cell factor (c-kit ligand) in myeloid leukemia. (1993) (17)
- Prognostic relevance of miRNA-155 methylation in anaplastic glioma (2016) (17)
- A long duration of the prediagnostic symptomatic interval is not associated with an unfavourable prognosis in childhood medulloblastoma. (2012) (17)
- Bevacizumab versus alkylating chemotherapy in recurrent glioblastoma (2019) (17)
- Genomic profiling reveals distinctive molecular relapse patterns in IDH1/2 wild‐type glioblastoma (2014) (17)
- Postponed is not canceled: role of craniospinal radiation therapy in the management of recurrent infant medulloblastoma--an experience from the HIT-REZ 1997 & 2005 studies. (2014) (16)
- Newly Diagnosed Metastatic Intracranial Ependymoma in Children: Frequency, Molecular Characteristics, Treatment, and Outcome in the Prospective HIT Series. (2019) (16)
- Medulloblastoma Harbor Somatic Mitochondrial DNA Mutations in the D-loop Region (2010) (16)
- Primitive neuroectodermal tumors of the brainstem in children treated according to the HIT trials: clinical findings of a rare disease. (2015) (16)
- FGFR1 N546K mutation in a case of papillary glioneuronal tumor (PGNT) (2014) (16)
- Serum levels of stem cell factor are increased in asymptomatic human immunodeficiency virus-infected patients and are associated with prolonged survival. (1995) (15)
- The FDA approved PI3K inhibitor GDC‐0941 enhances in vitro the anti‐neoplastic efficacy of Axitinib against c‐myc‐amplified high‐risk medulloblastoma (2018) (15)
- Absence of detectable alterations in the putative tumor suppressor gene BTRC in cerebellar medulloblastomas and cutaneous basal cell carcinomas (2003) (15)
- MYCN amplification predicts poor outcome for patients with supratentorial primitive neuroectodermal tumors of the central nervous system . (2014) (15)
- Meningioma as second malignant neoplasm after oncological treatment during childhood (2012) (15)
- PTEN mutations do not cause nuclear beta-catenin accumulation in endometrial carcinomas. (2004) (15)
- MRI Phenotype of RELA-fused Pediatric Supratentorial Ependymoma (2018) (15)
- Curative treatment for central nervous system medulloepithelioma despite residual disease after resection (2011) (15)
- Effects of Granulocyte Colony-Stimulating Factor in Children with Severe Congenital Neutropenia (1992) (15)
- Different vascular patterns of medulloblastoma and supratentorial primitive neuroectodermal tumors (1999) (14)
- Telomere elongation via alternative lengthening of telomeres (ALT) and telomerase activation in primary metastatic medulloblastoma of childhood (2019) (14)
- Low level of microsatellite instability in paediatric malignant astrocytomas (2008) (14)
- Inhibition of Gap Junctions Sensitizes Primary Glioblastoma Cells for Temozolomide (2019) (14)
- Abstract 3463: Treatment of young children with localized medulloblastoma by chemotherapy alone: Final results of the prospective multicenter trial HIT 2000 confirming the prognostic impact of histology (2011) (14)
- Early Wound Site Seeding in a Patient with Central Nervous System High-Grade Neuroepithelial Tumor with BCOR Alteration. (2018) (14)
- Intraventricular etoposide safety and toxicity profile in children and young adults with refractory or recurrent malignant brain tumors (2016) (14)
- Integrating Tenascin-C protein expression and 1q25 copy number status in pediatric intracranial ependymoma prognostication: A new model for risk stratification (2017) (14)
- Meclofenamate causes loss of cellular tethering and decoupling of functional networks in glioblastoma. (2021) (13)
- Cerebellar medullomyoblastoma with melanotic tubular structures (2008) (13)
- A Global View on the Availability of Methods and Information in the Neuropathological Diagnostics of CNS Tumors: Results of an International Survey Among Neuropathological Units (2016) (13)
- Biological material collection to advance translational research and treatment of children with CNS tumours: position paper from the SIOPE Brain Tumour Group. (2018) (13)
- Erratum to: Disseminated oligodendroglial-like leptomeningeal tumors: preliminary diagnostic and therapeutic results for a novel tumor entity (2015) (13)
- Medullomyoblastoma: a histological, immunohistochemical, ultrastructural and molecular genetic study (1998) (13)
- A phase II single-arm study of irinotecan in combination with temozolomide (TEMIRI) in children with newly diagnosed high grade glioma: a joint ITCC and SIOPE-brain tumour study (2013) (13)
- Pathology and Classification of Tumors of the Nervous System (2010) (13)
- Animal model of human medulloblastoma: clinical, magnetic resonance imaging, and histopathological findings after intra-cisternal injection of MHH-MED-1 cells into nude rats. (1997) (13)
- Dysembryoplastic Neuroepithelial Tumor of the Septum Pellucidum and the Supratentorial Midline: Histopathologic, Neuroradiologic, and Molecular Features of 7 Cases (2016) (13)
- Loss of efficacy of subsequent nonsurgical therapy after primary treatment failure in pediatric low‐grade glioma patients—Report from the German SIOP‐LGG 2004 cohort (2020) (13)
- Chromosomal imbalances and DNA amplifications in SV40 large T antigen-induced primitive neuroectodermal tumor cell lines of the rat. (1999) (13)
- Sensitive Determination of BRAF Copy Number in Clinical Samples by Pyrosequencing (2011) (13)
- Management of primary thalamic low-grade glioma in pediatric patients: results of the multicenter treatment studies HIT-LGG 1996 and SIOP-LGG 2004. (2017) (12)
- Medulloblastoma Displays Distinct Regional Matrix Metalloprotease Expression (2001) (12)
- Primary intracranial soft tissue sarcoma in children and adolescents: a cooperative analysis of the European CWS and HIT study groups (2013) (12)
- [Gastrointestinal stromal tumors carrying PDGFRalpha mutations occur preferentially in the stomach and exhibit an epithelioid or mixed phenotype]. (2004) (12)
- Management of Primary Tectal Plate Low-Grade Glioma in Pediatric Patients: Results of the Multicenter Treatment Study SIOP-LGG 2004 (2018) (12)
- Ependymomas in infancy: underlying genetic alterations, histological features, and clinical outcome (2020) (12)
- Local and Systemic Therapy of Recurrent Ependymoma in Children and Adolescents: Short- and Long-term Results of the E-HIT-REZ 2005 Study. (2020) (12)
- CTLA4 promoter methylation predicts response and progression-free survival in stage IV melanoma treated with anti-CTLA-4 immunotherapy (ipilimumab) (2020) (12)
- New developments in the pathology of skull base tumors (2001) (12)
- Comparison of automated silver enhanced in situ hybridization and fluorescence in situ hybridization for evaluation of epidermal growth factor receptor status in human glioblastomas (2009) (12)
- Rare ADAR and RNASEH2B variants and a type I interferon signature in glioma and prostate carcinoma risk and tumorigenesis (2017) (12)
- Pediatric ependymoma: an overview of a complex disease (2021) (12)
- Alternative lengthening of telomeres in molecular subgroups of paediatric high-grade glioma (2020) (11)
- FOCAD loss impacts microtubule assembly, G2/M progression and patient survival in astrocytic gliomas (2019) (11)
- Absence of chromosome 19q13.41 amplification in a case of atypical teratoid/rhabdoid tumor with ependymoblastic differentiation (2011) (11)
- Expression of granulocyte colony-stimulating factor in recurrent glial tumors is inversely correlated with tumor progression (1999) (11)
- Concurrent radiotherapy with temozolomide vs. concurrent radiotherapy with a cisplatinum-based polychemotherapy regimen (2018) (11)
- Ceritinib-Induced Regression of an Insulin-Like Growth Factor-Driven Neuroepithelial Brain Tumor (2019) (11)
- Somatostatin receptor subtype 2 (sst2) is a potential prognostic marker and a therapeutic target in medulloblastoma (2013) (11)
- Case of the month 1-2019: CNS high-grade neuroepithelial tumor with BCOR alteration (2018) (11)
- Long-term cognitive deficits in pediatric low-grade glioma (LGG) survivors reflect pretreatment conditions—report from the German LGG studies (2020) (10)
- Metabolic studies of human primitive neuroectodermal tumour cells by proton nuclear magnetic resonance spectroscopy. (1997) (10)
- Human peripheral blood granulocytes and myeloid leukemic cell lines express both transcripts encoding for stem cell factor (1994) (10)
- Evaluation of Prognostic Factors and Role of Participation in a Randomized Trial or a Prospective Registry in Pediatric and Adolescent Nonmetastatic Medulloblastoma – A Report From the HIT 2000 Trial (2020) (10)
- Occurrence of high‐grade glioma in Noonan syndrome: Report of two cases (2019) (10)
- Therapeutic implications of improved molecular diagnostics for rare CNS-embryonal tumor entities: results of an international, retrospective study. (2021) (10)
- Molecular characterization of disseminated pilocytic astrocytomas (2016) (10)
- Differential forms of p53 in medulloblastoma primary tumors, cell lines and xenografts. (2011) (10)
- CD95 ligand-induced apoptosis of human medulloblastoma cells. (1998) (10)
- Concurrent IDH1 and SMARCB1 Mutations in Pediatric Medulloblastoma: A Case Report (2018) (10)
- Frequent epigenetic inactivation of the chaperone SGNE1/7B2 in human gliomas (2012) (9)
- Musashi1 enhances chemotherapy resistance of pediatric glioblastoma cells in vitro (2019) (9)
- Identification of amplified genes from SV40 large T antigen-induced rat PNET cell lines by subtractive cDNA analysis and radiation hybrid mapping (2001) (9)
- Ependymoblastoma of the brainstem: MRI findings and differential diagnosis (2014) (9)
- Paucimannosidic glycoepitopes inhibit tumorigenic processes in glioblastoma multiforme (2019) (9)
- Monoclonal antibody T-199 directed against human medulloblastoma: characterization of a new antigenic system expressed on neuroectodermal tumors and natural killer cells. (1989) (9)
- Favorable prognosis in pediatric brainstem low‐grade glioma: Report from the German SIOP‐LGG 2004 cohort (2020) (9)
- Production of interleukin-1 beta and interleukin-6 in hepatoblastoma. (1993) (9)
- Analysis of the TSC2 gene in human medulloblastoma (2001) (9)
- CRX/OTX3: A Useful Marker in the Differential Diagnosis of Tumors of the Pineal Region and Indicator of Photoreceptor Differentiation in Medulloblastomas and Atypical Teratoid Rhabdoid Tumors (2013) (9)
- Rare histological variants in ependymomas: histopathological analysis of 13 cases (2011) (8)
- Altered splicing leads to reduced activation of CPEB3 in high-grade gliomas (2016) (8)
- Unusual clinico-pathological features in primary Hodgkin’s lymphomas of the central nervous system (2012) (8)
- Proportion of children with cancer that have an indication for genetic counseling and testing based on the cancer type irrespective of other features (2021) (8)
- Extracranial metastasizing solitary fibrous tumors (SFT) of meninges: Histopathological features of a case with long‐term follow‐up (2013) (8)
- What’s in a name? (2013) (8)
- The anti-neoplastic activity of Vandetanib against high-risk medulloblastoma variants is profoundly enhanced by additional PI3K inhibition (2017) (8)
- Molecular Diagnostics in Pediatric Brain Tumors: Impact on Diagnosis and Clinical Decision-Making — A Selected Case Series (2018) (8)
- The diagnostic role and clinical relevance of determination of BRAF status in brain tumors. (2013) (8)
- Assessment of Promoter Methylation Identifies PTCH as a Putative Tumor-suppressor Gene in Human CLL. (2016) (8)
- High frequency of disease progression in pediatric spinal cord low-grade glioma (LGG): Management strategies and results from the German LGG study group. (2020) (8)
- HIGH GRADE GLIOMAS (2012) (8)
- Spinal cord injury-induced expression of the antiangiogenic endostatin/collagen XVIII in areas of vascular remodelling. (2007) (7)
- Telomerase reverse transcriptase promoter mutation- and O6-methylguanine DNA methyltransferase promoter methylation-mediated sensitivity to temozolomide in isocitrate dehydrogenase-wild-type glioblastoma: is there a link? (2021) (7)
- Inhibition of Intercellular Cytosolic Traffic via Gap Junctions Reinforces Lomustine-Induced Toxicity in Glioblastoma Independent of MGMT Promoter Methylation Status (2021) (7)
- Frequent intragenic polymorphism in the 3‘ untranslated region of the lissencephaly gene 1 (LIS‐1) (1996) (7)
- Adults with CNS primitive neuroectodermal tumors/pineoblastomas: results of multimodal treatment according to the pediatric HIT 2000 protocol (2014) (7)
- High-Resolution Genomic Analysis of Cribriform Neuroepithelial Tumors of the Central Nervous System (2015) (7)
- Doubling Recruitment of Pediatric Low-grade Glioma within Two Decades does not change Outcome – Report from the German LGG Studies (2021) (7)
- OTX2 Defines a Subgroup of Atypical Teratoid Rhabdoid Tumors With Close Relationship to Choroid Plexus Tumors (2016) (7)
- Transthyretin expression in medulloblastomas and medulloblastoma cell lines (1995) (7)
- Ablation of T cell immunity differentially influences tumor risk in inbred BD rat strains (2009) (6)
- EGFR gene amplification and variant III (EGFRvIII) mutation in primary and recurrent glioblastoma. (2016) (6)
- MTSS1 is epigenetically regulated in glioma cells and inhibits glioma cell motility (2016) (6)
- Specificity and functional effects of antibodies to human stem cell factor. (1997) (6)
- Clinical, pathological, and molecular data on desmoplastic/nodular medulloblastoma: case studies and a review of the literature (2016) (6)
- Imaging Characteristics of Wingless Pathway Subgroup Medulloblastomas: Results from the German HIT/SIOP-Trial Cohort (2019) (6)
- Concordance between local, institutional, and central pathology review in glioblastoma: implications for research and practice: a pilot study. (2012) (6)
- [Inhibition of angiogenesis and growth of malignant gliomas in the athymic nude rat model: immunotherapy against "basic fibroblast growth factor"]. (1996) (6)
- Prognostic impact of distinct genetic entities in pediatric diffuse glioma WHO‐grade II—Report from the German/Swiss SIOP‐LGG 2004 cohort (2020) (6)
- MGMT promoter methylation analysis for allocating combined CCNU/TMZ chemotherapy: Lessons learned from the CeTeG/NOA‐09 trial (2020) (5)
- Two molecularly distinct atypical teratoid/rhabdoid tumors (or tumor components) occurring in an infant with rhabdoid tumor predisposition syndrome 1 (2019) (5)
- Voltage- and γ-aminobutyric acid-activated membrane currents in the human medulloblastoma cell line MHH-MED-3 (2000) (5)
- Natural and cryptic peptides dominate the immunopeptidome of atypical teratoid rhabdoid tumors (2021) (5)
- Natural history of a medulloblastoma: 30 months of wait and see in a child with a cerebellar incidentaloma (2013) (5)
- Hepatic stem cells in the human liver (1996) (5)
- NEURO/MEDICAL ONCOLOGY (2013) (4)
- DNA methylation profiling improves routine diagnosis of paediatric central nervous system tumours: A prospective population‐based study (2022) (4)
- Mitogenic Effect of Human Stem Cell Factor Alone or in Combination with G-CSF, GM-CSF, and IL-3 on Fresh Leukemic Blasts from Patients with Stem Cell Factor Receptor-Positive Acute Myeloid Leukemia (1992) (4)
- MBCL-07. NON-METASTATIC MEDULLOBLASTOMA OF EARLY CHILDHOOD: RESULTS FROM THE PROSPECTIVE CLINICAL TRIAL HIT-2000 AND AN EXTENDED VALIDATION COHORT (2020) (4)
- Treatment of Embryonal Tumours with Multilayered Rosettes with Carboplatin/Etoposide Induction and High-dose Chemotherapy within the Prospective P-HIT Trial. (2021) (4)
- Magnetic Resonance Imaging Characteristics of Molecular Subgroups in Pediatric H3 K27M Mutant Diffuse Midline Glioma (2021) (4)
- MHH-ES-1, A new Ewing sarcoma cell line (1989) (4)
- Molecular profiling of pediatric meningiomas shows tumor characteristics distinct from adult meningiomas (2021) (4)
- Human stem cell factor is a growth factor for myeloid leukemia cells. (1993) (4)
- BI-32RISK FACTOR ANALYSIS FOR PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA WHO DID NOT RECEIVE SALVAGE THERAPY (2014) (4)
- Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts (2022) (4)
- Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas (2022) (4)
- Systemic chemotherapy of pediatric recurrent ependymomas: results from the German HIT-REZ studies (2021) (4)
- A Marker for Diffuse High-Grade Astrocytomas (2016) (4)
- Medulloblastoma in Adults: Cytogenetic Phenotypes Identify Prognostic Subgroups. (2021) (4)
- ATRT–SHH comprises three molecular subgroups with characteristic clinical and histopathological features and prognostic significance (2022) (3)
- G-PCNSL-SG-1 randomized phase III trial of high-dose methotrexate with or without whole brain radiotherapy for primary central nervous system lymphoma: Long-term follow-up. (2014) (3)
- Histopathological grading of intracranial pediatric ependymomas (2008) (3)
- MET T992I mutation in a case of ependymoblastoma/embryonal tumour with multilayered rosettes (2014) (3)
- Medulloblastoma with extensive nodularity: a tumour exclusively of infancy? (2017) (3)
- Durable response to mTOR inhibition in a patient with relapsing papillary tumor of the pineal region (2018) (3)
- Mutated SON putatively causes a cancer syndrome comprising high-risk medulloblastoma combined with café-au-lait spots (2019) (3)
- Pathology and Classification of Tumors of the Central Nervous System (2019) (3)
- Relapsed Medulloblastoma in Pre-Irradiated Patients: Current Practice for Diagnostics and Treatment (2021) (3)
- GCT-76. 24Gy WHOLE VENTRICULAR RADIOTHERAPY ALONE IS SUFFICIENT FOR DISEASE CONTROL IN LOCALISED GERMINOMA IN CR AFTER INITIAL CHEMOTHERAPY – EARLY RESULTS OF THE SIOP CNS GCT II STUDY (2020) (3)
- Supplemental Information New Brain Tumor Entities Emerge from Molecular Classi fi cation of CNS-PNETs (2016) (3)
- EMBR-15. DIAGNOSTIC RE-EVALUATION AND POOLED CLINICAL DATA ANALYSIS OF PATIENTS WITH PREVIOUS DIAGNOSIS OF CNS-PNET (2018) (3)
- 1q gain is a frequent finding in preoperatively treated Wilms tumors, but of limited prognostic value for risk stratification in the SIOP2001/GPOH trial (2014) (3)
- Determining the glioma CpG island methylator phenotype, 1p/19q codeletion, and MGMT promoter methylation from epigenome-wide methylation data in the biomarker cohort of the NOA-04 trial. (2014) (3)
- MBCL-39. MEDULLOBLASTOMA IN PATIENTS WITH GORLIN SYNDROME: RESULTS FROM THE HIT STUDY GROUP (2018) (2)
- Combinatorial effects of azacitidine and trametinib on NRAS‐mutated melanoma (2021) (2)
- MB-89TREATMENT FAILURE IN YOUNG CHILDREN WITH DESMOPLASTIC MEDULLOBLASTOMA (DMB)/MEDULLOBLASTOMA WITH EXTENSIVE NODULARITY (MBEN) TREATED ACCORDING TO THE HIT PROTOCOLS. (2016) (2)
- LG-63MANAGEMENT OF PRIMARY TECTAL LOW-GRADE GLIOMA (LGG) IN PEDIATRIC PATIENTS: RESULTS OF THE MULTICENTER TREATMENT STUDY SIOP-LGG 2004 (2016) (2)
- Using CRISPR/Cas9 genome editing in human iPSCs for deciphering the pathogenicity of a novel CCM1 transcription start site deletion (2022) (2)
- Evaluation of dose, volume, and outcome in children with localized, intracranial ependymoma treated with proton therapy within the prospective KiProReg Study (2021) (2)
- LGG-23. REPEATED PROGRESSIONS IN PEDIATRIC CHIASMATIC-HYPOTHALAMIC GLIOMAS (CHG): CAN WE IDENTIFY SUCCESSFUL TREATMENT STRATEGIES? (2018) (2)
- Clinical and molecular subgroups of ependymoma in adulthood: An analysis of the German Glioma Network. (2017) (2)
- Quality assurance in neuropathology: Experiences from the round robin trials on IDH mutation and MGMT promoter methylation testing launched by the Quality Assurance Initiative Pathology (QuIP) in 2018 and 2019. (2020) (2)
- INCIDENTAL NEUROPATHOLOGICAL FINDINGS IN A CHILD WITH CERVICAL MENINGORADICULOCELE (2012) (2)
- No evidence to support the impact of migration background on treatment response rates and cancer survival: a retrospective matched-pair analysis in Germany (2021) (2)
- Hypothalamic papillary tumor in a patient with tuberous sclerosis. (2008) (2)
- Effects of the growth pattern of medulloblastoma on short-term neurological impairments after surgery: results from the prospective multicenter HIT-SIOP PNET 4 study. (2020) (2)
- Molecular heterogeneity characterizes glioblastoma with lipoblast/adipocyte-like cytology (2015) (2)
- Integrative Genomic Analyses of Atypical Teratoid Rhabdoid Tumours (ATRTs) (2014) (2)
- Xanthogranuloma, Rathkes cyst, and Childhood Craniopharyngioma: results of prospective multinational studies of children and adolescents with rare sellar malformations (2013) (2)
- Initial hypothalamic involvement is the major risk factor for impaired prognosis and quality of life in childhood craniopharyngioma regardless of chosen treatment strategies: results of KRANIOPHARYNGEOM 2000 (2012) (2)
- Group 3 medulloblastoma in a patient with a GYS2 germline mutation and glycogen storage disease 0a (2018) (2)
- [Neuropathology of medulloblastomas and other CNS embryonal tumors : Precision diagnostics through the integration of genetic markers]. (2019) (2)
- EMBR-08. CHOROID PLEXUS TUMORS IN 2018: THE CPT-SIOP EXPERIENCE AND LONG-TERM OUTCOME (2018) (2)
- GENE-08. THE MNP 2.0 STUDY: PROSPECTIVE INTEGRATION OF DNA METHYLATION PROFILING IN CNS TUMOR DIAGNOSTICS (2019) (2)
- RANK ( TNFRSF 11 A ) Is Epigenetically Inactivated and Induces Apoptosis in Gliomas 1 , 2 (2014) (2)
- p57 Is Not Mutated in Hepatoblastoma but Shows Increased Transcriptional Activity in a Comparative Analysis of the Three Imprinted Genes p57, IGF2, and H19 (2000) (2)
- Clinical Epidermal Growth Factor Receptor Variant III ( EGFRvIII ) Positivity in EGFR-Ampli fi ed Glioblastomas : Prognostic Role and Comparison between Primary and Recurrent Tumors (2017) (2)
- Xanthogranuloma of the sellar region – Results of a multicenter prospective study on diagnostics, therapy and prognosis in children and adolescents (2008) (1)
- Clinical and molecular features associated with long-term survival of elderly patients with glioblastoma. (2017) (1)
- Late complete remission of supratentorial primitive neuroectodermal tumor (CNS‐PNET) after multiple relapses (2011) (1)
- PNR-33MOLECULAR RE-EVALUATION OF INSTITUTIONALLY DIAGNOSED CNS-PNETS: CLINICAL CONSEQUENCES OF CONFINED DIAGNOSTIC GROUPS (2016) (1)
- Pediatric high-grade gliomas and the WHO CNS Tumor Classification—Perspectives of pediatric neuro-oncologists and neuropathologists in light of recent updates (2022) (1)
- Abstract LB-384: Targeting overexpressed Aurora kinases in childhood medulloblastoma: Antiproliferative effects of small molecule inhibitors ZM44739, VX680 and shRNA (2010) (1)
- Long-term survival in primary glioblastoma revisited: The contribution of isocitrate dehydrogenase mutations. (2013) (1)
- Abstract 1446: Sonic hedgehog-associated medulloblastoma arising from the cochlear nuclei of the brainstem (2012) (1)
- New developments and controversies in the neuropathology of malignant gliomas. (1999) (1)
- EPEN-39. CLINICAL STRATIFIED TREATMENT OF LOCALIZED PEDIATRIC INTRACRANIAL EPENDYMOMA WITH COMBINED LOCAL IRRADIATION AND CHEMOTHERAPY WITHIN THE PROSPECTIVE, MULTICENTER E-HIT TRIAL – THE MOLECULAR SUBGROUP MATTERS (2020) (1)
- TB-11MOLECULAR NEUROPATHOLOGY 2.0 - INCREASING DIAGNOSTIC ACCURACY IN PEDIATRIC NEUROONCOLOGY (2016) (1)
- ETMR-14. TREATMENT OF EMBRYONAL TUMOURS WITH MULTILAYERED ROSETTES (ETMR) WITH CARBOPLATIN-ETOPOSIDE INDUCTION AND TANDEM HIGH-DOSE CHEMOTHERAPY WITHIN THE PROSPECTIVE HIT-TRIALS AND REGISTRIES (2020) (1)
- Polyclonal Resistance in Gastrointestinal Stromal Tumor Treated with Sequential Kinase Inhibitors (2006) (1)
- Long-term follow-up of surgical intervention pattern in pediatric low-grade gliomas: report from the German SIOP-LGG 2004 cohort. (2022) (1)
- Current status of phase III anti-EGF-receptor antibody (OSAG-101) for newly diagnosed glioblastoma. (2010) (1)
- Preclinical target analyisis in pediatric malignancies for selecting targeted compounds: Innovative therapies for children with cancer. (2005) (1)
- Local and Systemic Therapy of Recurrent Medulloblastomas in Children and Adolescents: Results of the P-HIT-REZ 2005 Study (2022) (1)
- Post-Operative Hypothalamic Lesions and Obesity in Childhood Craniopharyngioma - Results of the Multinational Prospective Trial KRANIOPHARYNGEOM 2000 after Three Year Follow-up (2473 words) short running title: Hypothalamic lesions in childhood craniopharyngioma (2011) (1)
- Targeting HSP90 in pediatric malignancies by the European Consortium "Innovative Therapies for Children with Cancer" (2007) (1)
- ACTR-53. MGMT PROMOTER METHYLATION ANALYSIS FOR ALLOCATING COMBINED CCNU/TMZ CHEMOTHERAPY: LESSONS LEARNED FROM THE CeTeG/NOA-09 TRIAL (2019) (1)
- Shows Increased Transcriptional Activity in a Comparative Analysis of the Three Imprinted Genes (2000) (1)
- EPEN-07. EPENDYMOMAS IN INFANCY: UNDERLYING GENETIC ALTERATIONS, HISTOLOGICAL FEATURES AND CLINICAL OUTCOME (2019) (1)
- Defining the Spectrum, Treatment and Outcome of Patients With Genetically Confirmed Gorlin Syndrome From the HIT-MED Cohort (2021) (1)
- First randomized multicenter study in patients with childhood craniopharyngioma analyzing the appropriate time point of irradiation after incomplete resection – study design of KRANIOPHARYNGEOM 2007 (2006) (1)
- Prognostic impact of obesity in newly-diagnosed glioblastoma: a secondary analysis of CeTeG/NOA-09 and GLARIUS (2022) (1)
- Author Correction: YAP1/TAZ drives ependymoma-like tumour formation in mice (2020) (1)
- OMICS AND PROGNSTIC MARKERS (2013) (1)
- MBCL-21. EARLY CHILDHOOD MEDULLOBLASTOMA: SUBGROUP-SPECIFIC SURVIVAL IN PATIENTS TREATED WITH SYSTEMIC CHEMOTHERAPY AND INTRAVENTRICULAR MTX TO AVOID CRANIOSPINAL RADIOTHERAPY (2018) (1)
- Abstract 2492: Integrated genomics on molecular subgroups in medulloblastoma (2012) (1)
- Deciphering the real incidence of medulloblastoma with extensive nodularity in adult patients (2016) (1)
- OT-10IMPLEMENTATION OF NEXT GENERATION COPY NUMBER AND MUTATIONAL ANALYSIS IN ROUTINE NEUROPATHOLOGY: MOLECULAR INVERSION PROFILING IS A HELPFUL TOOL IN DIFFERENTIAL DIAGNOSTICS AND PROGNOSTIFICATION OF PEDIATRIC BRAIN TUMORS (2015) (1)
- Correspondence re: J. Benítez et al., A region of allelic imbalance in 1q31-32 in primary breast cancer coincides with a recombination hot spot. Cancer Res., 57: 4217-4220, 1997. (1998) (1)
- PEDIATRICS CLINICAL RESEARCH (2010) (1)
- Abstract LB-83: Molecular stratification of medulloblastoma: comparison of histological and genetical methods to detect Wnt activated tumors. (2013) (1)
- Pediatric neuro-oncology in small centers--quality control of network support: the HIT-GBM experience. (2011) (1)
- Molecular classification of diffuse cerebral gliomas using genome- and transcriptome-wide profiling. (2015) (1)
- NFM-11. PEDIATRIC MENINGIOMAS ARE MOLECULARLY DISTINCT FROM ADULT COUNTERPARTS (2018) (1)
- LG-06MANAGEMENT OF PRIMARY THALAMIC LOW-GRADE GLIOMA IN PEDIATRIC PATIENTS: RESULTS OF THE MULTICENTER TREATMENT STUDIES HIT-LGG 1996 AND SIOP-LGG 2004 (2016) (1)
- MB-24ROUTINE DIAGNOSTIC MEDULLOBLASTOMA SUBGROUPING USING LOW-COST, LOW-INPUT DNA METHYLOMICS: APPLICATION TO TRIALS COHORTS PREVIOUSLY REFRACTORY-TO-ANALYSIS (2016) (1)
- Transitioning to molecular diagnostics in pediatric high-grade glioma: experiences with the 2016 WHO classification of CNS tumors (2021) (1)
- AT-59HIGH-DOSE MTX-BASED CHEMOTHERAPY FOR PRIMARY CNS LYMPHOMA: WITH OR WITHOUT WHOLE BRAIN RADIOTHERAPY? FINAL ANALYSIS OF G-PCNSL-SG-1 (2014) (1)
- Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology (2023) (1)
- The PI3K inhibitor pictilisib and the multikinase inhibitors pazopanib and sorafenib have an impact on Rac1 level and migration of medulloblastoma in vitro (2022) (1)
- TBIO-07. ASSESSING THE UTILITY OF DNA METHYLATION PROFILING IN BRAIN TUMOR DIAGNOSTICS—THE PROSPECTIVE MNP2.0 STUDY (2018) (0)
- MB-46PROGNOSTIC RELEVANCE OF EPIGENETIC/BIOLOGICAL SUBGROUPS AND MYCC/MYCN GENE AMPLIFICATION IN A HOMOGENOUSLY TREATED METASTATIC MEDULLOBLASTOMA HIT2000 COHORT AGED 4-21 YEARS (2016) (0)
- PNR-09EVALUATION OF AGE-DEPENDENT TREATMENT STRATEGIES FOR CHILDREN AND YOUNG ADULTS WITH PINEOBLASTOMA: ANALYSIS OF POOLED SIOP-E AND HEAD START DATA (2016) (0)
- HGG-16. Final analysis of the HIT-HGG-2007 trial (ISRCTN19852453): Significant survival benefit for pontine and non-pontine pediatric high-grade gliomas in comparison to previous HIT-GBM-C/-D trials. (2022) (0)
- MPTH-23. LONG-TERM SURVIVAL WITH GLIOBLASTOMA IN THE ELDERLY (2016) (0)
- Deciphering the AT/RT ligandome (2018) (0)
- HGG-59. Pediatric high-grade gliomas and the WHO classification on CNS Tumors - Different perspectives of pediatric neuro-oncologists and neuropathologists in the light of recent updates (2022) (0)
- MEDB-37. Chemotherapy response prediction by molecular risk factors in metastatic childhood medulloblastoma (2022) (0)
- PNR-25ETMR—FREQUENCY, CLINICAL PRESENTATION, TREATMENT AND OUTCOME OF 29 PATIENTS TREATED WITHIN THE HIT TRIALS (2016) (0)
- GCT-11. 24 Gy whole ventricular radiotherapy alone is sufficient for disease control in localised germinoma in CR after initial chemotherapy – final of the SIOP CNS GCT II study (2022) (0)
- Clinical and molecular characterization of isolated M1 disease in pediatric medulloblastoma: experience from the German HIT-MED studies (2022) (0)
- CSIG-27. DIFFERENTIAL ELEVATION OF TERT ACTIVITY AND SENSITIVITY TO TEMOZOLOMIDE BY TYPE OF TERT MUTATION IN MGMT PROMOTER-METHYLATED GLIOBLASTOMA (2018) (0)
- HGG-34. DETECTION OF ONCOGENIC FUSION EVENTS IN SUPRATENTORIAL GLIOBLASTOMAS OF YOUNG CHILDREN (2020) (0)
- ATRT-15. SPINAL CORD ATYPICAL TERATOID/RHABDOID TUMORS (AT/RT) IN CHILDREN: RESULTS OF A EUROPEAN RETROSPECTIVE ANALYSIS UNDER THE AUSPICES OF THE EU-RHAB STUDY GROUP (2018) (0)
- MBCL-09. ISOLATED M1 METASTASES IN PEDIATRIC MEDULLOBLASTOMA: IS POSTOPERATIVE RADIOTHERAPY FOLLOWED BY MAINTENANCE CHEMOTHERAPY SUPERIOR TO POSTOPERATIVE SANDWICH-CHEMOTHERAPY AND RADIOTHERAPY? (2020) (0)
- Expression of drugable targets in pediatric malignancies: Innovative therapies for children with cancer (2007) (0)
- MEDB-61. Genetic alterations ofTP53 andOTX2 indicate increased risk of relapse in WNT medulloblastomas (2022) (0)
- Medulloblastoma in adults: identifying imaging biomarkers of genetic status in a prospective multi-centre study (2017) (0)
- GCT-48. OUTCOME OF CNS MALIGNANT NON-GERMINOMATOUS GERM CELL TUMORS (GCT) WITH AFP > 1000 ng/ml AT DIAGNOSIS TREATED ACCORDING TO SIOP CNS GCT 96 (2020) (0)
- First Report of Glioblastoma and Associated PNKP Mutation (2021) (0)
- QOL-04. Histology, treatment, and extent of pretreatment hydrocephalus are major determents of neurocognitive outcome for survivors of pediatric posterior fossa tumors - report from the German HIT-studies (2022) (0)
- Risk prediction in early childhood SHH medulloblastoma treated with radiation-avoiding chemotherapy: Evidence for more than two subgroups. (2023) (0)
- Glioblastoma centre and periphery: two aspects of the same disease (2009) (0)
- MEDB-14. Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome (2022) (0)
- Improved risk-stratification for posterior fossa ependymoma of childhood considering clinical, histological and genetic features – a retrospective analysis of the HIT ependymoma trial cohort (2019) (0)
- A 78‐Year‐Old Male with a Right Occipital Lesion (2013) (0)
- OS2.2 Chemotherapy for spinal gliomas in adults (2019) (0)
- Unearthing Hidden Genomic Data in Solid Tumor Samples: Are Your FFPE Samples Revealing All? (2013) (0)
- Abstract 1432: The heterogeneous genomic landscape of posterior fossa ependymoma (2012) (0)
- RARE-12. Pineoblastoma of children and young adults in a national population: An analysis of the HIT-MED study cohort (2022) (0)
- COMMENT ON : A REGION OF ALLELIC IMBALANCE IN 1Q31-32 IN PRIMARY BREAST CANCER COINCIDES WITH A RECOMBINATION HOT SPOT BY J. BENITEZ ET AL. (1998) (0)
- Abstract 4702: Chromosome 2p gain andN-Mycamplification predict poor outcome of patients with LIN28 negative supratentorial primitive neuroectodermal tumors of the central nervous system (CNS-PNET).. (2013) (0)
- HIGH GRADE GLIOMAS AND DIPG (2014) (0)
- PATH-08. DNA methylation profiling improves routine diagnostics of paediatric CNS tumours: a prospective population-based study (2022) (0)
- ETMR-10. Retrospective molecular re-evaluation of CNS PNETs; a population-based study (2022) (0)
- Minimal methylation classifier (MIMIC): A novel method for derivation and rapid diagnostic detection of disease-associated DNA methylation signatures (2017) (0)
- PATH-13. PLEOMORPHIC XANTHOASTROCYTOMA INTEGRATED GENOMIC CHARACTERIZATION - WHAT HAVE WE LEARNED? (2020) (0)
- PATH-24. MOLECULAR SUBGROUPS OF ADULT EPENDYMAL TUMORS: AN ANALYSIS OF THE GERMAN GLIOMA NETWORK (2017) (0)
- 13 INVITED KidsCancerKinome: a EU-FP6 project for preclinical kinase inhibitor evaluation as a tool to prioritize compounds for paediatric development (2008) (0)
- Clinical and pathologic data of 32 patients with GISTs under imatinib treatment (2006) (0)
- HG-85INTER-OBSERVER AGREEMENT IN NEUROPATHOLOGICAL HGG DIAGNOSIS : EXPERIENCE OF THE PRE-RANDOMISATION CENTRAL REVIEW IN THE HERBY TRIAL. (2016) (0)
- ACTIVATION OF THE HEDGEHOG-PATCHED-SIGNALING PATHWAY IN PANCREATIC ADENOCARCINOMAS (2005) (0)
- Akt and mTORC1 signaling as predictive biomarkers for the EGFR antibody nimotuzumab in glioblastoma (2018) (0)
- EMBR-25. GENOME-WIDE GENETIC AND EPIGENETIC ASSESSMENT OF GROUP 4 MEDULLOBLASTOMA FOR IMPROVED, BIOMARKER DRIVEN, PROGNOSTICATION AND RISK-STRATIFICATION (2021) (0)
- Biochemical Characterization and Regulation of Expression of the Binding Protein for the Granulocyte Colony-Stimulating Factor on Leukemia Cells (1992) (0)
- Meningiomas in childhood and adolescence – Multicenter cross-sectional study on 42 patients (2008) (0)
- MPTH-52. GENOMIC LANDSCAPE OF ADULT MEDULLOBLASTOMAS CLASSIFIED ACCORDING TO WHO 2016 GUIDELINES (2016) (0)
- Abstract LB-205: Genome-wide copy number analysis of pediatric hepatocellular carcinomas: Identification of characteristic aberrations (2014) (0)
- Optimising biomarkers for accurate ependymoma diagnosis, prognostication and stratification within International Clinical Trials: A BIOMECA study (2022) (0)
- Chemotherapy for adult patients with spinal cord gliomas. (2021) (0)
- MEDB-68. Analysis of telomeres length and Alternative Lengthening of Telomeres (ALT) in molecular subgroups of infant medulloblastoma (2022) (0)
- Synthesis and Neoangiogenesis ( Flt-1 ) / Vascular Endothelial Growth Factor Receptor-1 Astrocytomas Is Associated with Fms-like Tyrosine Kinase-1 Expression of the Ets-1 Transcription Factor in Human Updated (1999) (0)
- CTNI-67. DUAL INHIBITION OF POST-RADIOGENIC ANGIO-VASCULOGENESIS BY OLAPTESED PEGOL (NOX-A12) AND BEVACIZUMAB IN GLIOBLASTOMA – INTERIM DATA FROM THE FIRST EXPANSION ARM OF THE GERMAN PHASE 1/2 GLORIA TRIAL (2022) (0)
- Human Stem Cell Factor: Biological Effects and Receptor Expression on Myeloid Leukemia Cells (1992) (0)
- EPEN-24. Biological markers of ependymoma in children and adolescents (BIOMECA): Systematic comparison of methods for the precise evaluation of biomarkers for ependymoma diagnosis and prognostication (2022) (0)
- Abstract LB-82: Chromosome 1q gain as genetic marker for risk stratification of pediatric ependymoma patients - validation as an adverse prognostic marker in the German multicenter HIT2000 trial. (2013) (0)
- MBCL-31. A WHOLE CHROMOSOME ABERRATION PHENOTYPE IN NON-WNT/NON-SHH TUMORS PREDICTS OUTCOME WITHIN STANDARD-RISK MEDULLOBLASTOMAS FROM THE HIT-SIOP-PNET4 CLINICAL TRIAL (2018) (0)
- PNR-30EFFECTIVITY OF TWO DIFFERENT RADIATION-AVOIDING TREATMENT REGIMENS FOR YOUNG CHILDREN WITH PINEOBLASTOMA—RESULTS OF THE HIT2000 TRIAL (2016) (0)
- Supratentorial CNS-PNETs in children; a Swedish population-based study with molecular re-evaluation and long-term follow-up (2023) (0)
- OS02.1 Multicenter pilot study of radio-chemotherapy as first-line treatment for adults with medulloblastoma - the NOA-07 trial (2017) (0)
- HG-27ACUTE TOXICITY OF TEMOZOLOMIDE- VERSUS CISPLATIN-BASED RADIOCHEMOTHERAPY IN PEDIATRIC HIGH GRADE GLIOMA: COMPARATIVE ANALYSIS OF PROSPECTIVE, CONSECUTIVE, MULTICENTRIC AND MULTINATIONAL TRIALS OF THE GERMAN HIT-HGG STUDY GROUP (2016) (0)
- HG-75CLINICAL, RADIOLOGICAL, AND HISTO-GENETIC CHARACTERISTICS OF LONG-TERM SURVIVORS OF DIFFUSE INTRINSIC PONTINE GLIOMA: A COLLABORATIVE REPORT FROM THE INTERNATIONAL AND SIOP-E DIPG REGISTRIES (2016) (0)
- Randomized multicenter trial on patients wit childhood craniopharyngioma (KRANIOPHARYNGEOM 2007) – Update after 12 months of recruitment (2008) (0)
- GC-02CNS GERMINOMAS ARE CHARACTERIZED BY GLOBAL DEMETHYLATION, CHROMOSOMAL INSTABILITY AND MUTATIONAL ACTIVATION OF THE KIT-, RAS/RAF/ERK- AND AKT-PATHWAYS (2015) (0)
- Molecular Neuropathology and 49th Annual Meeting of the German Society of Neuropathology and Neuroanatomy (2004) (0)
- EMBR-12. IMPROVED DIAGNOSTIC ALGORITHM FOR DIFFERENTIAL DIAGNOSTICS OF CNS EMBRYONAL TUMORS (FORMER CNS-PNET) BY NEUROPATHOLOGICAL RE-EVALUATION OF 256 CASES AND CROSSVALIDATION BY METHYLATION CLASSIFICATION (2018) (0)
- Mutated SON putatively causes a cancer syndrome comprising high-risk medulloblastoma combined with café-au-lait spots (2019) (0)
- RANK (TNFRSF11A )I s Epigenetically Inactivated and Induces Apoptosis (2012) (0)
- A Sequential Targeting Strategy Interrupts AKT-Driven Subclone-Mediated Progression in Glioblastoma (2022) (0)
- The KidsCancerKinome: Validation of Cell Cycle Genes as Potential Drug Targets in Pediatric Tumors (2011) (0)
- Cancer Therapy : Preclinical Anticancer Effects of Niclosamide in Human Glioblastoma (2013) (0)
- Abstract 3425: Expression and functional role of erbB2 in human hepatoblastoma (2010) (0)
- Neuropathology and molecular diagnosis of brain tumors. Where are we in 2015? An international survey on diagnostic practices (2016) (0)
- EPEN-27. CDKN2A DELETION IN SUPRATENTORIAL EPENDYMOMA WITH RELA ALTERATION INDICATES A DISMAL PROGNOSIS – A RETROSPECTIVE ANALYSIS OF THE HIT EPENDYMOMA TRIAL COHORT (2020) (0)
- Correlation of the c-kit mutational status of gastrointestinal stromal tumors with the clinical response to the tyrosine kinase inhibitor imatinib (2004) (0)
- LG-01. MULTI-FOCAL OR DISSEMINATED LOW GRADE GLIOMA IN CHILDREN: THE RILEY HOSPITAL FOR CHILDREN EXPERIENCE (2012) (0)
- RO-23RECURRENT EPENDYMOMA A CHALLENGING THERAPY: RE-IRRADIATION PROLONGS SURVIVAL IN FAILURE OF RADICAL RESECTION (2016) (0)
- MBCL-11. CONCURRENT IDH1 AND SMARCB1 MUTATIONS IN A PEDIATRIC MEDULLOBLASTOMA: A CASE REPORT (2018) (0)
- Pseudoprogression is frequent following front-line radiotherapy in pediatric low-grade glioma - results from the German LGG cohort. (2021) (0)
- CLIN-PEDIATRICS CLINICAL RESEARCH (2012) (0)
- Abstract C116: The KidsCancerKinome: Validation of drug targets for high risk childhood cancers (2009) (0)
- GE-25NEXT GENERATION COPY NUMBER ANALYSIS BY MOLECULAR INVERSION PROFILING - A HELPFUL TOOL IN DIAGNOSTICS AND PROGNOSTIFICATION OF TUMORS OF THE CNS. (2014) (0)
- EPEN-09. IMPACT OF MOLECULAR SUBGROUP ON OUTCOME FOR INFANTS <12 MONTHS WITH INTRACRANIAL EPENDYMOMA - GERMAN EXPERIENCE FROM HIT2000, INTERIM-2000-REGISTRY AND I-HIT-MED REGISTRY (2020) (0)
- Longitudinal heterogeneity in glioblastoma: moving targets in recurrent versus primary tumors (2019) (0)
- JS04.4.A Beyond β-catenin: Genetic alterations ofTP53 andOTX2 and older age indicate increased risk of relapse in WNT medulloblastomas (2022) (0)
- Abstract LB-514: Contribution of ADAM17 to Kit ligand ectodomain shedding in high-grade gliomas (2012) (0)
- Shift towards less radical, hypothalamus-sparing treatment strategies in childhood craniopharyngioma – Comparison between patients recruited in KRANIOPHARYNGEOM 2000 and 2007 (2014) (0)
- Abstract 4351: A mammalian mitochondrial ribosomal protein contributes to intrinsic and extrinsic pathways for apoptosis in high grade gliomas of childhood (2010) (0)
- MEDB-51. Impact of residual tumor on outcomes in children and adolescents with medulloblastoma in the German HIT-cohort (2022) (0)
- 4100 ORAL Radiation Therapy in Childhood Low Grade Glioma (LGG) – a Subgroup Analysis Within the Scope of the German Multicenter Treatment Study HIT-LGG 1996 (2011) (0)
- BIOM-59. TERT PROMOTER MUTATION AND MGMT PROMOTER METHYLATION-MEDIATED SENSITIVITY TO TEMOZOLOMIDE IN IDH-WILDTYPE GLIOBLASTOMA: IS THERE A LINK? (2020) (0)
- Frontal cystic lesion with a contrast-enhancing mural nodule: Question (2017) (0)
- RARE-10. MULTICENTER PILOT STUDY OF RADIO-CHEMOTHERAPY AS FIRST-LINE TREATMENT FOR ADULTS WITH MEDULLOBLASTOMA – THE NOA-07 TRIAL. (2017) (0)
- 8 INVITED KidsCancerKinome; Looking for new targets in paediatric cancers (2007) (0)
- EPN-20NEWLY DIAGNOSED METASTATIC INTRACRANIAL EPENDYMOMA IN CHILDREN: FREQUENCY, TREATMENT AND OUTCOME IN THE POPULATION BASED, PROSPECTIVE HIT-SERIES. (2016) (0)
- HG-34HIGH-GRADE GLIOMA ARISING IN SURVIVORS OF PEDIATRIC ACUTE LYMPHOBLASTIC MALIGNANCIES: A COOPERATIVE ANALYSIS OF THE GERMAN HIT-HGG/-GBM AND ALL-BFM/COALL STUDIES (2016) (0)
- Catenin Gene β Degradation Targeting Box of the Childhood Hepatoblastomas Frequently Carry a Mutated Updated (1999) (0)
- Abstract C114: The KidsCancerKinome: Validation of CDK2 as potential drug target in pediatric tumors (2009) (0)
- MHH-NB11, A new neuroblastoma cell line (1989) (0)
- EPEN-06. CHEMOTHERAPY OF RECURRENT EPENDYMOMA: LONG-TERM RESPONSE ONLY IN FEW CASES (2020) (0)
- MEDB-04. Young children with metastatic medulloblastoma: frequent requirement for radiotherapy in children with non-WNT/non-SHH medulloblastoma despite highly intensified chemotherapy – Results of the MET-HIT2000-BIS4 trial (2022) (0)
- Abstract 196: Functional role of death-associated protein 3 in high grade gliomas of childhood (2011) (0)
- MEDB-35. Relationship between genetic profile, histology, clinical features and long-term outcome in young children medulloblastoma (YCMB) treated with upfront high dose chemotherapy (HDCT) in Italy (2022) (0)
- HGG-21. Oncogenic tyrosine kinase gene fusions in infant-type hemispheric gliomas - comparison of RNA- and DNA-based methods for their reliable detection (2022) (0)
- Molecular characterisation defines clinically-actionable heterogeneity within Group 4 medulloblastoma and improves disease risk-stratification (2023) (0)
- LGG-15. REQUIREMENT OF ADJUVANT TREATMENT IN CHILDHOOD LOW GRADE GLIOMAS (LGG) OF THE SPINAL CORD: EXPERIENCES FROM THE GERMAN LGG STUDY GROUP (2018) (0)
- Mutations of BRAF in low-grade Astrocytomas (2008) (0)
- GCT-29. DOES TUMOUR MARKER DECLINE PREDICT OUTCOME IN INTRACRANIAL NON-GERMINOMATOUS GERM CELL TUMOURS (NGGCTs)? (2020) (0)
- Extensive genomic demethylation - a histological hallmark of germinomatous tumors (2006) (0)
- MEDB-17. Re-irradiation for recurrent medulloblastoma in a matched cohort: Advantageous especially in patients without resection (2022) (0)
- Microarray analysis of differential methylation during glioma progression (2004) (0)
- Correlation of conventional magnetic resonance imaging features with O6-methylguanine-DNA-methyltransferase gene promoter methylation status and survival outcomes in patients with newly diagnosed glioblastoma: Single-center correlative imaging substudy from a prospective clinical trial (2018) (0)
- Erratum: SIOP-E-BTG and GPOH Guidelines for Diagnosis and Treatment of Children and Adolescents with Low Grade Glioma (Klinische Padiatrie (2019) 231 (107-135) DOI: 10.1055/a-0889-8256) (2019) (0)
- PATH-32. GENOMIC LANDSCAPE AND BIOLOGY OF MEDULLOBLASTOMA IN ADULTS (2019) (0)
- MEDB-71. Molecular characterisation of group 4 medulloblastoma improves risk-stratification and its biological understanding (2022) (0)
- IMMU-28. DECIPHERING THE AT/RT LIGANDOME (2018) (0)
- MBCL-11. TIME TO RADIOTHERAPY IMPACTS SURVIVAL IN PEDIATRIC AND ADOLESCENT NON-METASTATIC MEDULLOBLASTOMA TREATED BY UPFRONT RADIOTHERAPY – A REPORT FROM THE HIT 2000 TRIAL (2020) (0)
- Abstract LB-324: A whole chromosome aberration phenotype in non-WNT/non-SHH tumors predicts outcome within standard-risk medulloblastomas from the HIT-SIOP-PNET4 clinical trial (2018) (0)
- MOLECULAR GENETIC DETERMINANTS OF LONG-TERM SURVIVAL WITH GLIOBLASTOMA (2014) (0)
- Methylation class oligosarcoma may encompass IDH-wildtype gliomas (2022) (0)
- BIOM-08. DNA METHYLATION-BASED SUBGROUPING PREDICTS SURVIVAL BENEFIT FROM LOMUSTINE/TEMOZOLOMID COMBINATION THERAPY IN MGMT PROMOTOR-METHYLATED GLIOBLASTOMA (2021) (0)
- Abstract LB-216: Frequent oncogenic tyrosine kinase gene fusions in supratentorial glioblastomas of young children (2020) (0)
- MBCL-45. ROLE OF IRRADIATION IN RELAPSED MEDULLOBLASTOMA: A REPORT OF THE GERMAN MEDULLOBLASTOMA RELAPSE STUDIES (2018) (0)
- Frontal cystic lesion with a contrast-enhancing mural nodule: Answer (2017) (0)
- Differential elevation of TERT activity and sensitivity to temozolomide by type of TERT mutation in MGMT promoter-methylated glioblastoma. (2018) (0)
- Abstract 4348: PDGF-Rα expression and activation of the MAPK pathway in disseminated pilocytic astrocytomas (2010) (0)
- 2.O.07 KIDSCANCERKINOME; KINASE DRUG TARGETS IN PAEDIATRIC CANCERS (2010) (0)
- Short communication Allelic loss at 10q23.3 but lack of mutation of PTEN/MMAC1 in chromophobe renal cell carcinoma (2001) (0)
- Molecular pathological insights reveal a high number of unfavorable risk patients among children treated for medulloblastoma and CNS‐PNET in Oslo 2005–2017 (2022) (0)
- Low grade glioma in pediatric NF-1 patients (2008) (0)
- Abstract 3561: Recurrent genetic alterations in epigenetic pineoblastoma subtypes (2023) (0)
- Abstract 2492: Identification of RBMS1 in the amplified region 2q24 as a major driver of cellular growth in childhood hepatoblastoma (2022) (0)
- Abstract 2588: Targeting overexpressed PLK1 and Aurora kinases in childhood medulloblastoma (2011) (0)
- Effects of Granulocyte Colony-Stimulating Factor in Children with Severe Cnngenital Neutropenia * (2005) (0)
- HGG-28. ONCOGENIC TYROSINE KINASE GENE FUSIONS IN SUPRATENTORIAL HIGH GRADE GLIOMAS OF YOUNG CHILDREN - COMPARISON OF RNA- AND DNA-BASED METHODS FOR THEIR RELIABLE DETECTION (2021) (0)
- GENE-13. PEDIATRIC MENINGIOMAS ARE CHARACTERIZED BY DISTINCT METHYLATION PROFILES DIFFERENT FROM ADULT MENINGIOMAS (2018) (0)
- LGG-14. PEDIATRIC DIFFUSE GLIOMA WHO-GRADE II: PROGNOSTIC IMPACT OF MOLECULAR GENETIC VARIANTS (2018) (0)
- The molecular landscape of ETMR at diagnosis and relapse (2019) (0)
- EPEN-36. THE TREATMENT OUTCOME OF PAEDIATRIC SUPRATENTORIAL C11ORF95-RELA FUSED EPENDYMOMA: A COMBINED REPORT FROM E-HIT SERIES AND AUSTRALIAN NEW ZEALAND CHILDREN’S HAEMATOLOGY/ONCOLOGY GROUP (2020) (0)
- Identification of genetic alterations in pediatric hepatocellular carcinomas (2014) (0)
- MBCL-06. RISK STRATIFICATION IMPROVEMENT OF THE HIT2000 AND I-HIT-MED COHORTS USING MOLECULAR SUBTYPES I-VIII OF GROUP 3/4 MEDULLOBLASTOMAS (2020) (0)
- H3F3A-G34R mutant high grade neuroepithelial neoplasms with glial and dysplastic ganglion cell components (2019) (0)
- QOL-13. NEUROCOGNITIVE OUTCOMES ACCORDING TO RISK-ADAPTED TREATMENT REGIMENS FOR CHILDREN OLDER THAN 4 WITH MEDULLOBLASTOMA AND POSTERIOR FOSSA EPENDYMOMA – RESULTS OF THE HIT2000 TRIAL (2020) (0)
- PATH-27. GIANT CELL GLIOBLASTOMA DOES NOT REPRESENT A DISTINCT TUMOUR ENTITY BUT STRATIFIES INTO DIFFERENT GENETICALLY DEFINED SUBTYPES (2019) (0)
- QOS-26HEALTH-RELATED QUALITY OF LIFE (HRQOL) IN HIT-SIOP-PNET4 TRIAL SURVIVORS: DIFFERENCES BETWEEN MEDULLOBLASTOMA MOLECULAR SUBGROUPS (2016) (0)
- Em-24. Telomerase Inhibition Induces Growth Arrest in Paediatric Ependymoma (2012) (0)
- A Matched-pair Analysis on the Effect of Migration Background on Response Rates and Survival of Cancer Patients Treated at a Comprehensive Cancer Center in Germany (2020) (0)
- Childhood Craniopharyngioma: Changes of Treatment Strategies in Multinational Trials During the Last 12 Years (2014) (0)
- MEDB-41. Identifying a subgroup of patients with early childhood sonic hedgehog-activated medulloblastoma with unfavorable prognosis after treatment with radiation-sparing regimens including intraventricular methotrexate (2022) (0)
- Abstract 4797: A member of the SLC25 family is epigenetically inactivated in human gliomas and suppresses cell growthin vitro (2011) (0)
- MB-24 Routine diagnostic medulloblastoma subgrouping using low-cost, low-input DNA methylomics: Application to trials cohorts previously refractory-to-analysis [conference abstract] (2016) (0)
- MB-28GENOME-WIDE COPY NUMBER ANALYSIS, NEUROPATHOLOGICAL CLASSIFICATION AND ANALYSIS OF HEDGEHOG ACTIVATION: HISTOLOGY REFLECTS GENETICS AND BIOLOGY IN MEDULLOBLASTOMAS OF YOUNG CHILDREN (2015) (0)
- c-Kit gene mutations in intracranial germ cell tumors (2010) (0)
- HGG-49. Gliomatosis cerebri in children: A collaborative report from the European Society for Pediatric Oncology (SIOPE) (2022) (0)
- Childhood Craniopharyngioma – Changes of treatment strategies in the multinational prospective trials KRANIOPHARYNGEOM 2000/2007 (2013) (0)
- Early wound site seeding in a patient with CNS high-grade neuroepithelial tumor with BCOR alteration : A case report Running title : Wound site seeding in CNS HGNET-BCOR tumor (2019) (0)
- MEDB-16. Persistent radiological lesions at the end of primary therapy in childhood medulloblastoma: residual lesion or active residual tumor? (2022) (0)
- PATH-11. PROSPECTIVE (EPI-)GENETIC CLASSIFICATION OF > 1,000 PEDIATRIC CNS TUMORS—THE MNP 2.0 STUDY (2020) (0)
- EPEN-19. Impact of molecular classification on prognosis in children and adolescents with spinal ependymoma: Results from the HIT-MED database (2022) (0)
- HGG-24. MOLECULAR, PATHOLOGICAL, RADIOLOGICAL AND IMMUNE PROFILING OF NON-BRAINSTEM PAEDIATRIC HIGH GRADE GLIOMA FROM THE HERBY PHASE II RANDOMISED TRIAL (2018) (0)
- Abstracts of the 52nd Workshop for Pediatric Research (2017) (0)
- MBCL-29. FEASIBILITY OF SCREENING AND REASONS FOR SCREENING FAILURES IN THE SIOPE PNET 5 MB TRIAL (2018) (0)
- WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma (2014) (0)
- EPID-18. NOONAN SYNDROME CAN BE ASSOCIATED WITH HIGH GRADE GLIOMA; A REPORT OF TWO CASES (2017) (0)
- P45: Comprehensive genomic analysis of desmoplastic medulloblastomas reveals novel amplified genes and supports a monoclonal origin of the different histologic components (2005) (0)
- PNR-32UPDATE OF DIAGNOSTICS OF PRIMITIVE NEUROECTODERMAL TUMOURS OF THE CNS - NEUROPATHOLOGICAL RE-EVALUATION OF 99 CASES (2016) (0)
- Abstract C115: The KidsCancerKinome: Validation of Aurora kinases as potential drug targets in pediatric tumors (2009) (0)
- Correction: SIOP-E-BTG and GPOH Guidelines for Diagnosis and Treatment of Children and Adolescents with Low Grade Glioma (2019) (0)
- An 11 Year Old Child with a Right Parieto‐Occipital Lesion (2015) (0)
- TMIC-47. IMMUNOBIOLOGICAL CHARACTERIZATION OF CNS GERMINOMAS – EVIDENCE FOR INFLAMMATORY AND SUPPRESSIVE IMMUNOLOGICAL MECHANISMS (2017) (0)
- Spinal glioneuronal tumors: location matters!-Reply. (2016) (0)
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What Schools Are Affiliated With Torsten Pietsch?
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