Toshiharu (toshi) Nagatsu

Toshiharu (toshi) Nagatsu's AcademicInfluence.com Rankings

Biology

#2686

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#4238

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Molecular Biology

#163

World Rank

#167

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Neuroscience

#234

World Rank

#248

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Biochemistry

#227

World Rank

#285

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biology Degrees

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Biology

Toshiharu (toshi) Nagatsu's Degrees

Bachelors Chemistry University of California, Berkeley

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Toshiharu (toshi) Nagatsu's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

TYROSINE HYDROXYLASE. THE INITIAL STEP IN NOREPINEPHRINE BIOSYNTHESIS. (1964) (1936)
Tumor necrosis factor-α (TNF-α) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients (1994) (820)
Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene (1994) (744)
Interleukin-1β, interleukin-6, epidermal growth factor and transforming growth factor-α are elevated in the brain from parkinsonian patients (1994) (717)
Distribution of major histocompatibility complex class II-positive microglia and cytokine profile of Parkinson's disease brains (2003) (616)
The newly synthesized selective Ca2+/calmodulin dependent protein kinase II inhibitor KN-93 reduces dopamine contents in PC12h cells. (1991) (526)
Photometric assay of dopamine- -hydroxylase activity in human blood. (1972) (499)
A RAPID AND SIMPLE RADIOASSAY FOR TYROSINE HYDROXYLASE ACTIVITY. (1964) (489)
Changes in cytokines and neurotrophins in Parkinson's disease. (2000) (462)
Interleukin (IL)-1β, IL-2, IL-4, IL-6 and transforming growth factor-α levels are elevated in ventricular cerebrospinal fluid in juvenile parkinsonism and Parkinson's disease (1996) (439)
Tumor necrosis factor-alpha (TNF-alpha) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients. (1994) (435)
Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription (2000) (413)
Inflammatory process in Parkinson's disease: role for cytokines. (2005) (396)
Interleukin-1 beta, interleukin-6, epidermal growth factor and transforming growth factor-alpha are elevated in the brain from parkinsonian patients. (1994) (371)
Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease (1999) (368)
Role of cytokines in inflammatory process in Parkinson's disease. (2006) (326)
Inhibitors of purified beef adrenal tyrosine hydroxylase. (1965) (321)
New chromogenic substrates for X-prolyl dipeptidyl-aminopeptidase. (1976) (316)
[Biochemistry of Parkinson's disease]. (1988) (303)
A quantitative-trait analysis of human plasma-dopamine beta-hydroxylase activity: evidence for a major functional polymorphism at the DBH locus. (2001) (277)
Caspase activities and tumor necrosis factor receptor R1 (p55) level are elevated in the substantia nigra from Parkinsonian brain (2000) (265)
[Tyrosine hydroxylase]. (1969) (263)
Neuroprotective Effects of Glial Cell Line-Derived Neurotrophic Factor Mediated by an Adeno-Associated Virus Vector in a Transgenic Animal Model of Amyotrophic Lateral Sclerosis (2002) (254)
Interleukin (IL)-1 beta, IL-2, IL-4, IL-6 and transforming growth factor-alpha levels are elevated in ventricular cerebrospinal fluid in juvenile parkinsonism and Parkinson's disease. (1996) (241)
Isoquinoline neurotoxins in the brain and Parkinson's disease (1997) (231)
Highly sensitive assay for tyrosine hydroxylase activity by high-performance liquid chromatography. (1979) (220)
Interleukin‐10 Inhibits Both Production of Cytokines and Expression of Cytokine Receptors in Microglia (1999) (219)
Targeted Disruption of the Tyrosine Hydroxylase Locus Results in Severe Catecholamine Depletion and Perinatal Lethality in Mice (*) (1995) (209)
An endogenous substance of the brain, tetrahydroisoquinoline, produces parkinsonism in primates with decreased dopamine, tyrosine hydroxylase and biopterin in the nigrostriatal regions (1988) (207)
Expression of mRNAs for neuropeptide receptors and β-adrenergic receptors in human osteoblasts and human osteogenic sarcoma cells (1997) (202)
p53 protein, interferon-γ, and NF-κB levels are elevated in the parkinsonian brain (2007) (197)
Ablation of Cerebellar Golgi Cells Disrupts Synaptic Integration Involving GABA Inhibition and NMDA Receptor Activation in Motor Coordination (1998) (196)
A link between stress and depression: Shifts in the balance between the kynurenine and serotonin pathways of tryptophan metabolism and the etiology and pathophysiology of depression (2008) (195)
Triple transduction with adeno-associated virus vectors expressing tyrosine hydroxylase, aromatic-L-amino-acid decarboxylase, and GTP cyclohydrolase I for gene therapy of Parkinson's disease. (2000) (189)
Cytokines in Parkinson's disease. (2000) (183)
Behavioral recovery in a primate model of Parkinson's disease by triple transduction of striatal cells with adeno-associated viral vectors expressing dopamine-synthesizing enzymes. (2002) (181)
Delayed delivery of AAV-GDNF prevents nigral neurodegeneration and promotes functional recovery in a rat model of Parkinson's disease (2002) (171)
Biochemistry of postmortem brains in Parkinson's disease: historical overview and future prospects. (2007) (169)
Synaptic integration mediated by striatal cholinergic interneurons in basal ganglia function. (2000) (164)
Requirement of neuropilin 1-mediated Sema3A signals in patterning of the sympathetic nervous system. (2002) (163)
Immunohistochemical evidence that central serotonin neurons produce dopamine from exogenousl-DOPA in the rat, with reference to the involvement of aromaticl-amino acid decar☐ylase (1994) (158)
Cytosolic Catechols Inhibit α-Synuclein Aggregation and Facilitate the Formation of Intracellular Soluble Oligomeric Intermediates (2006) (154)
Isolation of a novel cDNA clone for human tyrosine hydroxylase: alternative RNA splicing produces four kinds of mRNA from a single gene. (1987) (153)
Cytokines in Parkinson’s Disease (2000) (148)
Fusaric acid, a hypotensive agent produced by fungi. (1969) (147)
Human dopamine beta-hydroxylase gene: two mRNA types having different 3'-terminal regions are produced through alternative polyadenylation. (1989) (146)
Characterization of Mouse and Human GTP Cyclohydrolase I Genes (1995) (143)
Transforming growth factor-β1 levels are elevated in the striatum and in ventricular cerebrospinal fluid in Parkinson's disease (1995) (143)
Tyrosine hydroxylase: human isoforms, structure and regulation in physiology and pathology. (1995) (139)
Aromatic L-amino acid decarboxylase activity in central and peripheral tissues and serum of rats with L-DOPA and L-5-hydroxytryptophan as substrates. (1981) (136)
Structure of the human tyrosine hydroxylase gene: alternative splicing from a single gene accounts for generation of four mRNA types. (1988) (135)
Dopamine β-hydroxylase: two polymorphisms in linkage disequilibrium at the structural gene DBH associate with biochemical phenotypic variation (1998) (133)
Catecholamines and Serotonin Are Differently Regulated by Tetrahydrobiopterin (2001) (132)
Ascorbic acid and adriamycin toxicity. (1991) (127)
Successive cleavage of N-terminal Arg1--Pro2 and Lys3-Pro4 from substance P but no release of Arg1-Pro2 from bradykinin, by X-Pro dipeptidyl-aminopeptidase. (1978) (124)
Behavioral recovery in 6-hydroxydopamine-lesioned rats by cotransduction of striatum with tyrosine hydroxylase and aromatic L-amino acid decarboxylase genes using two separate adeno-associated virus vectors. (1998) (122)
Tissue-specific and high-level expression of the human tyrosine hydroxylase gene in transgenic mice (1991) (121)
Molecular mechanism of the relation of monoamine oxidase B and its inhibitors to Parkinson's disease: possible implications of glial cells. (2006) (119)
Progress in monoamine oxidase (MAO) research in relation to genetic engineering. (2004) (118)
L-dopa therapy for Parkinson's disease: Past, present, and future (2009) (118)
Changes in Prolyl Endopeptidase During Maturation of Rat Brain and Hydrolysis of Substance P by the Purified Enzyme (1980) (117)
Cellular and Molecular Mechanisms of Parkinson’s Disease: Neurotoxins, Causative Genes, and Inflammatory Cytokines (2006) (117)
p53 protein, interferon-gamma, and NF-kappaB levels are elevated in the parkinsonian brain. (2007) (116)
Biopterin in human brain and urine from controls and parkinsonian patients: application of a new radioimmunoassay. (1981) (116)
Population genetics of a functional variant of the dopamine beta-hydroxylase gene (DBH). (1997) (116)
Conversion of L-tyrosine to 3,4-dihydroxyphenylalanine by cell-free preparations of brain and sympathetically innervated tissues. (1964) (115)
Vascular and brain dopamine beta-hydroxylase activity in young spontaneously hypertensive rats. (1976) (115)
Inhibition of dopamine beta-hydroxylase by sulfhydryl compounds and the nature of the natural inhibitors. (1967) (114)
A simple and sensitive assay for dopamine-beta-hydroxylase activity by dual-wavelength spectrophotometry. (1974) (114)
Purification of aminopeptidase A in human serum and degradation of angiotensin II by the purified enzyme. (1970) (113)
L-Threo-3, 4-Dihydroxyphenylserine Treatment for Akinesia and Freezing of Parkinsonism (1981) (113)
bcl-2 Protein is increased in the brain from parkinsonian patients (1996) (112)
Phenylethanolamine N-methyltransferase and other enzymes of catecholamine metabolism in human brain. (1977) (112)
A new and highly sensitive voltammetric assay for aromatic L-amino acid decarboxylase activity by high-performance liquid chromatography. (1979) (111)
A N-methyltransferase in human brain catalyses N-methylation of 1,2,3,4-tetrahydroisoquinoline into N-methyl-1,2,3,4-tetrahydroisoquinoline, a precursor of a dopaminergic neurotoxin, N-methylisoquinolinium ion. (1989) (108)
Isolation and characterization of a cDNA clone encoding human aromatic L-amino acid decarboxylase. (1989) (108)
Cytokine production of activated microglia and decrease in neurotrophic factors of neurons in the hippocampus of Lewy body disease brains (2005) (108)
Molecular cloning of genomic DNA and chromosomal assignment of the gene for human aromatic L-amino acid decarboxylase, the enzyme for catecholamine and serotonin biosynthesis. (1992) (102)
The soluble form of Fas molecule is elevated in parkinsonian brain tissues (1996) (102)
increased dopamine and serotonin metabolism in rat nucleus accumbens produced by intracranial self-stimulation of medial forebrain bundle as measured by in vivo microdialysis (1989) (100)
Juvenile parkinsonism--some clinical, pharmacological, and neuropathological aspects. (1984) (100)
Purification and properties of glycylprolyl -naphthylamidase in human submaxillary gland. (1972) (99)
IMMUNOFLUORESCENT STUDIES ON TYROSINE HYDROXYLASE: APPLICATION FOR ITS AXOPLASMIC TRANSPORT (1977) (98)
Molecular Genetics of Dopa-Responsive Dystonia (1999) (97)
Stimulus-coupled interaction of tyrosine hydroxylase with 14-3-3 proteins. (1999) (97)
N‐Methylation of Dopamine‐Derived 6,7‐Dihydroxy‐1,2,3,4‐Tetrahydroisoquinoline, (R)‐Salsolinol, in Rat Brains: In Vivo Microdialysis Study (1992) (97)
Catecholamine Synthesis in Rabbits with Neurogenic Hypertension (1969) (96)
IMMUNOFLUORESCENT STUDIES ON THE LOCALIZATION OF TYROSINE HYDROXYLASE AND DOPAMINE-β-HYDROXYLASE IN THE MES-, DI-, AND TELENCEPHALON OF THE RAT USING UNPERFUSED FRESH FROZEN SECTIONS (1979) (96)
Parkinsonism in monkeys produced by chronic administration of an endogenous substance of the brain, tetrahydroisoquinoline: The behavioral and biochemical changes (1990) (94)
Presence of 2-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline and 1,2-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, novel endogenous amines, in parkinsonian and normal human brains. (1991) (94)
Brain β2-microglobulin levels are elevated in the striatum in Parkinson's diseaselevels are elevated in the striatum in Parkinson's disease (1995) (94)
Fluorescence assay of x-prolyl dipeptidyl-aminopeptidase activity with a new fluorogenic substrate. (1978) (92)
A collaborative study on the malignant syndrome in Parkinson's disease and related disorders. (2003) (92)
Multiple mRNA forms of human GTP cyclohydrolase I. (1992) (92)
Serum dopamine β-hydroxylase activity in developing hypertensive rats (1974) (91)
Urinary putrescine, spermidine, and spermine in human blood and solid cancers and in an experimental gastric tumor of rats. (1976) (90)
Age‐dependent and tissue‐specific CAG repeat instability occurs in mouse knock‐in for a mutant Huntington's disease gene (2001) (88)
Reduction of adriamycin toxicity by ascorbate in mice and guinea pigs. (1982) (87)
Oxidation of N‐Methyl‐1,2,3,4‐Tetrahydroisoquinoline into the N‐Methyl‐Isoquinolinium Ion by Monoamine Oxidase (1989) (85)
Quantification of mRNA of tyrosine hydroxylase and aromatic L-amino acid decarboxylase in the substantia nigra in Parkinson's disease and schizophrenia (1994) (84)
Aromaticl-amino acid decar☐ylase-immunoreactive neurons in and around the cerebrospinal fluid-contacting neurons of the central canal do not contain dopamine or serotonin in the mouse and rat spinal cord (1988) (82)
Parkinson's disease: changes in apoptosis-related factors suggesting possible gene therapy (2002) (78)
Presence of tetrahydroisoquinoline, a parkinsonism-related compound, in foods. (1989) (76)
Immunotoxin-mediated conditional disruption of specific neurons in transgenic mice. (1995) (75)
A new and highly sensitive fluorescence assay for collagenase-like peptidase activity. (1979) (74)
Increase in level of tumor necrosis factor (TNF)-α in 6-hydroxydopamine-lesioned striatum in rats without influence of systemic l-DOPA on the TNF-α induction (1999) (74)
Determinants of cardiac noradrenaline depletion in human congestive failure. (1973) (73)
Human tyrosine hydroxylase in Parkinson’s disease and in related disorders (2018) (73)
Simple purification of aromatic L-amino acid decarboxylase from human pheochromocytoma using high-performance liquid chromatography. (1985) (73)
Brain‐specific gene expression by immortalized microglial cell‐mediated gene transfer in the mammalian brain (1998) (73)
Basic, Clinical, and Therapeutic Aspects of Alzheimer’s and Parkinson’s Diseases (1990) (72)
Intramuscular injection of AAV-GDNF results in sustained expression of transgenic GDNF, and its delivery to spinal motoneurons by retrograde transport (2003) (71)
Effects of Aging on Neuroprotective and Neurotoxic Properties of Microglia in Neurodegenerative Diseases (2008) (71)
Bradykinase activity of aloe extract. (1976) (70)
Does tyrosinase exist in neuromelanin-pigmented neurons in the human substantia nigra? (1998) (70)
Rapid chromatographic purification of dipeptidyl peptidase IV in human submaxillary gland. (1980) (69)
Effects of repeated systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to mice on interleukin-1β and nerve growth factor in the striatum (1998) (69)
Modest Neuropsychological Deficits Caused by Reduced Noradrenaline Metabolism in Mice Heterozygous for a Mutated Tyrosine Hydroxylase Gene (2000) (69)
Tyrosine Hydroxylase Activity in Caudate Nucleus from Parkinson's Disease: Effects of Iron and Phosphorylating Agents (1988) (68)
A novel brain-derived member of the epidermal growth factor family that interacts with ErbB3 and ErbB4. (1997) (66)
Interleukin-2 but not basic fibroblast growth factor is elevated in parkinsonian brain (2005) (66)
glycylprolyl β-naphthylamidase activity in human serum (1975) (66)
Differential effect of self-stimulation on dopamine release and metabolism in the rat medial frontal cortex, nucleus accumbens and striatum studied by in vivo microdialysis (1992) (65)
X-Prolyl dipeptidyl-aminopeptidase activity, with X-proline p-nitroanilides as substrates, in normal and pathological human sera. (1976) (65)
Tissue-specific alternative splicing of the first exon generates two types of mRNAs in human aromatic L-amino acid decarboxylase. (1992) (65)
Two novel cell surface antigens on small cell lung carcinoma defined by mouse monoclonal antibodies NE-25 and PE-35. (1986) (64)
Inhibitory Action of Chlorpromazine on the Oxidation of D-Amino-Acid in the Diencephalon Part of the Brain (1956) (64)
Molecular cloning of cDNA and chromosomal assignment of the gene for human phenylethanolamine N-methyltransferase, the enzyme for epinephrine biosynthesis. (1988) (64)
Genes for human catecholamine-synthesizing enzymes. (1991) (61)
Inhibition of the tyrosine hydroxylase system by MPTP, 1-methyl-4-phenylpyridinium ion (MPP+) and the structurally related compounds in vitro and in vivo. (1987) (61)
Tyrosine hydroxylase (TH), its cofactor tetrahydrobiopterin (BH4), other catecholamine-related enzymes, and their human genes in relation to the drug and gene therapies of Parkinson’s disease (PD): historical overview and future prospects (2016) (60)
Molecular cloning of the human Nurr1 gene: characterization of the human gene and cDNAs. (1999) (59)
Liquid chromatography of plasma catecholamines, with electrochemical detection, after treatment with boric acid gel. (1984) (59)
DRD2 allele frequencies and linkage disequilibria, including the -141CIns/Del promoter polymorphism, in European-American, African-American, and Japanese subjects. (1998) (59)
Primary structure of mouse tyrosine hydroxylase deduced from its cDNA. (1991) (58)
Increase in level of tumor necrosis factor-α in 6-hydroxydopamine-lesioned striatum in rats is suppressed by immunosuppressant FK506 (2000) (57)
Transforming growth factor-beta 1 levels are elevated in the striatum and in ventricular cerebrospinal fluid in Parkinson's disease. (1995) (57)
N-methylated tetrahydroisoquinolines as dopaminergic neurotoxins. (1993) (56)
Prevention and treatment of malignant syndrome in Parkinson's disease: a consensus statement of the malignant syndrome research group. (2003) (56)
Tyrosine Hydroxylase, Tryptophan Hydroxylase, Biopterin, and Neopterin in the Brains of Normal Controls and Patients with Senile Dementia of Alzheimer Type (1987) (56)
Role of N-terminus of tyrosine hydroxylase in the biosynthesis of catecholamines (2009) (55)
Catecholamine-related enzymes and the biopterin cofactor in Parkinson's disease and related extrapyramidal diseases. (1984) (55)
Clinical effects of L-threo-3,4-dihydroxyphenylserine in cases of parkinsonism and pure akinesia. (1987) (55)
Cloning and sequencing of cDNA encoding human sepiapterin reductase--an enzyme involved in tetrahydrobiopterin biosynthesis. (1991) (54)
Inhibition of dopamine beta-hydroxylase by 5-alkylpicolinic acid and their hypotensive effects. (1969) (54)
Kinetic properties of tyrosine hydroxylase purified from bovine adrenal medulla and bovine caudate nucleus. (1982) (53)
The effect of uptake inhibition on dopamine release from the nucleus accumbens of rats during self- or forced stimulation of the medial forebrain bundle: A microdialysis study (1989) (52)
Simple assay procedure for tyrosine hydroxylase activity by high-performance liquid chromatography employing coulometric detection with minimal sample preparation. (1988) (52)
Glial cell line-derived neurotrophic factor in the substantia nigra from control and parkinsonian brains (2001) (52)
Inhibition of Tyrosine Hydroxylase by R and S Enantiomers of Salsolinol, 1‐Methyl‐6,7‐Dihydroxy‐1,2,3,4‐ Tetrahydroisoquinoline (1992) (52)
An improved dual-wavelength spectrophotometric assay for dopamine-β-hydroxylase (1978) (52)
DL-threo-3,4-dihydroxyphenylserine for freezing symptom in parkinsonism. (1984) (50)
Selective inhibition of complex I by N-methylisoquinolinium ion and N-methyl-1,2,3,4-tetrahydroisoquinoline in isolated mitochondria prepared from mouse brain (1992) (50)
Biological Sciences: Adrenal Tyrosine Hydroxylase and Dopamine β-Hydroxylase in Spontaneously Hypertensive Rats (1971) (50)
Biochemistry of catecholamines;: The biochemical method (1973) (49)
Studies on Tyrosine Hydroxylase System in Rat Brain Slices Using High‐Performance Liquid Chromatography with Electrochemical Detection (1983) (49)
Migration of tetrahydroisoquinoline, a possible parkinsonian neurotoxin, into monkey brain from blood as proved by gas chromatography-mass spectrometry. (1988) (49)
Retrograde axoplasmic transport of inactive dopamine-β-hydroxylase in sciatic nerves (1976) (49)
Detection of inactive or less active forms of tyrosine hydroxylase in human adrenals by a sandwich enzyme immunoassay. (1984) (49)
Radioimmunoassay for biopterin in body fluids and tissues. (1981) (49)
Distribution of post-proline cleaving enzyme in human brain and the peripheral tissues (1980) (48)
Regulation of pteridine-requiring enzymes by the cofactor tetrahydrobiopterin (1999) (48)
Motor and learning dysfunction during postnatal development in mice defective in dopamine neuronal transmission (1998) (48)
Inhibition of Monoamine Oxidase by 3,4‐Dihydroxyphenylserine (1986) (48)
Activities of dipeptidyl peptidase II and dipeptidyl peptidase IV in synovial fluid from patients with rheumatoid arthritis and osteoarthritis. (1989) (47)
Migration activity of microglia and macrophages into rat brain (1997) (47)
Tetrahydrobiopterin-dependent functional recovery in 6-hydroxydopamine-treated rats by intracerebral grafting of fibroblasts transfected with tyrosine hydroxylase cDNA. (1992) (47)
A missense mutation in a patient with guanosine triphosphate cyclohydrolase I deficiency missed in the newborn screening program. (1995) (47)
GTP cyclohydrolase I gene in hereditary progressive dystonia with marked diurnal fluctuation (1995) (46)
The effects of pyridinium salts, structurally related compounds of 1-methyl-4-phenylpyridinium ion (MPP+), on tyrosine hydroxylation in rat striatal tissue slices (1986) (46)
Functional and high level expression of human dopamine beta-hydroxylase in transgenic mice. (1994) (46)
Effect of pyridoxal phosphate deficiency on aromatic L-amino acid decarboxylase activity with L-DOPA and L-5-hydroxytryptophan as substrates in rats. (1982) (45)
Characterization of Wild‐Type and Mutants of Recombinant Human GTP Cyclohydrolase I (1999) (45)
Neurotrophins and cytokines in Parkinson's disease. (1999) (45)
A branch site mutation leading to aberrant splicing of the human tyrosine hydroxylase gene in a child with a severe extrapyramidal movement disorder (2000) (45)
Selective toxicity of 5-S-cysteinyldopa, a melanin precursor, to tumor cells in vitro and in vivo. (1980) (45)
Demonstration of aromatic l-amino acid decarboxylase activity in human brain with l-dopa and l-5-hydroxytryptophan as substrates by high-performance liquid chromatography with electrochemical detection (1982) (45)
Synthesis of l‐3,4‐Bihydroxyphenylalanine by Tyrosine Hydroxylase cDNA‐Transfected C6 Cells: Application for Intracerebral Grafting (1989) (45)
Homospecific activity (activity per enzyme protein) of tyrosine hydroxylase increases in parkinsonian brain (2005) (44)
Inhibition of tyrosine hydroxylation in tissue slices of the rat striatum by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (1985) (44)
Effects of repeated systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on striatal tyrosine hydroxylase activity in vitro and tyrosine hydroxylase content (1987) (44)
Activities of dipeptidyl peptidase II and dipeptidyl peptidase IV in mice with lupus erythematosus-like syndrome and in patients with lupus erythematosus and rheumatoid arthritis. (1987) (44)
Brain beta 2-microglobulin levels are elevated in the striatum in Parkinson's disease. (1995) (44)
Significant behavioral recovery in Parkinson's disease model by direct intracerebral gene transfer using continuous injection of a plasmid DNA-liposome complex. (1998) (43)
Activated microglia affect the nigro‐striatal dopamine neurons differently in neonatal and aged mice treated with 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (2007) (43)
Cytotoxicity of dopamine-derived 6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolines. (1993) (43)
Cloning and sequencing of cDNA encoding mouse GTP cyclohydrolase I. (1993) (43)
Biopterin cofactor and monoamine-synthesizing monooxygenases (1983) (43)
Methods in neurotransmitter and neuropeptide research (1993) (42)
Cloning and structural organization of the gene encoding the mouse glial cell line-derived neurotrophic factor, GDNF. (1997) (42)
Characterization of Recombinant Human Aromatic l‐Amino Acid Decarboxylase Expressed in COS Cells (1990) (42)
TYROSINE HYDROXYLASE IN BOVINE CAUDATE NUCLEUS (1971) (42)
Immunohistocytochemical localization of the neurons containing catecholamine-synthesizing enzymes and serotonin in the brain of bullfrog (rana catesbiana). (1983) (42)
Novel toxins and Parkinson's disease: N-methylation and oxidation as metabolic bioactivation of neurotoxin. (1994) (42)
Effects of moclobemide on forced-swimming stress and brain monoamine levels in mice (1996) (42)
Analysis of the human tyrosine hydroxylase promoter-chloramphenicol acetyltransferase chimeric gene expression in transgenic mice. (1992) (42)
Amine-related neurotoxins in Parkinson's disease: past, present, and future. (2002) (41)
Increase in level of tumor necrosis factor (TNF)-alpha in 6-hydroxydopamine-lesioned striatum in rats without influence of systemic L-DOPA on the TNF-alpha induction. (1999) (41)
Serum glycylproline p-nitroanilidase activity in rheumatoid arthritis and systemic lupus erythematosus. (1978) (40)
Structure of the mouse tyrosine hydroxylase gene. (1992) (40)
N-methylisoquinolinium ion as an inhibitor of tyrosine hydroxylase, aromatic l-amino acid decarboxylase and monoamine oxidase (1989) (40)
Urinary 4-hydroxy-3-methoxymandelic (vanillylmandelic) acid, 4-hydroxy-3-methoxyphenylacetic (homovanillic) acid, and 5-hydroxy-3-indoleacetic acid determined by liquid chromatography with electrochemical detection. (1983) (40)
(6R)‐Tetrahydrobiopterin Increases the Activity of Tryptophan Hydroxylase in Rat Raphe Slices (1986) (39)
Dopamine Inhibition of Human Tyrosine Hydroxylase Type 1 Is Controlled by the Specific Portion in the N‐Terminus of the Enzyme (1999) (39)
Phosphorylation of the N-terminal portion of tyrosine hydroxylase triggers proteasomal digestion of the enzyme. (2011) (39)
Concentrations of neopterin and biopterin in the cerebrospinal fluid of patients with Parkinson's disease. (1990) (39)
Kinetic properties of tyrosine hydroxylase with natural tetrahydrobiopterin as cofactor. (1981) (39)
The catecholamine system in health and disease —Relation to tyrosine 3-monooxygenase and other catecholamine-synthesizing enzymes— (2007) (38)
Multiple mRNAs of monkey tyrosine hydroxylase. (1990) (38)
IV. Determination of aromatic L-amino acid decarboxylase in serum of various animals by high-performance liquid chromatography with electrochemical detection☆ (1981) (38)
Molecular Biology of Catecholamine-Related Enzymes in Relation to Parkinson's Disease (1999) (38)
Genomic structure and tissue distribution of the mouse dopamine D4 receptor (1995) (38)
Mechanism of inhibition of D-amino acid oxidase. IV. Inhibitory action of chlorpromazine. (1960) (37)
Catecholamine Synthesis and Release (1997) (37)
Expression of four types of human tyrosine hydroxylase in COS cells (1988) (37)
Evidence for the involvement of Ca2+-calmodulin and cyclic AMP in the regulation of the tyrosine hydroxylase system in rat striatal tissue slices. (1985) (36)
A selective Ca2+/calmodulin-dependent protein kinase II inhibitor, KN-62, inhibits the enhanced phosphorylation and the activation of tyrosine hydroxylase by 56 mM K+ in rat pheochromocytoma PC12h cells. (1991) (36)
Adenosine 3',5'-monophosphate-dependent protein kinase and amylase secretion from rat parotid gland. (1974) (36)
Serum activities of dipeptidyl-aminopeptidase II and dipeptidyl-aminopeptidase IV in tumor-bearing animals and in cancer patients. (1987) (36)
Coexpression of GTP cyclohydrolase I and inducible nitric oxide synthase mRNAs in mouse osteoblastic cells activated by proinflammatory cytokines (1998) (35)
Cysteinyldopamine is not incorporated into neuromelanin (1991) (35)
Analysis of the Alternative Promoters that Regulate Tissue‐Specific Expression of Human Aromatic l‐Amino Acid Decarboxylase (1995) (35)
Manganese mimics the action of 1-methyl-4-phenylpyridinium ion, a dopaminergic neurotoxin, in rat striatal tissue slices (2001) (34)
Characterization of protein kinases from bovine parotid glands. The effect of tolbutamide and its derivative on these partially purified enzymes. (1976) (34)
Isolation of a full-length cDNA clone encoding human tyrosine hydroxylase type 3. (1987) (34)
Serum glycylproline p-nitroanilidase activity in blood cancers. (1977) (34)
Peptidase activity of glycylprolyl beta-naphthylamidase from human submaxillary gland. (1974) (34)
Early and late effects of systemically administered 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on tyrosine hydroxylase activity in vitro and on tyrosine hydroxylation in tissue slices of mouse striatum (1986) (34)
Simultaneous fluorometry of urinary dopamine, norepinephrine, and epinephrine compared with liquid chromatography with electrochemical detection. (1982) (34)
Increased heterogeneity of tyrosine hydroxylase in humans. (1993) (34)
Recombinant human tyrosine hydroxylase types 1-4 show regulatory kinetic properties for the natural (6R)-tetrahydrobiopterin cofactor. (1994) (33)
Quinoline and quninaldine as naturally occurring inhibitors specific for type A monoamine oxidase. (1987) (33)
IL-1β and TNF-α suppress apolipoprotein (APO) E secretion and APO A-I expression in HepG2 cells (1998) (33)
Exogenousl-5-hydroxytryptophan is decarboxylated in neurons of the substantia nigra pars compacta and locus coeruleus of the rat (1995) (33)
Molecular genetics of tyrosine 3-monooxygenase and inherited diseases. (2005) (33)
Changes in cell characteristics due to culture conditions in cell lines from human small cell lung cancer. (1986) (32)
PURIFICATION AND PROPERTIES OF MITOCHONDRIAL MONOAMINE OXIDASE IN BEEF BRAIN (1971) (32)
Effects of stress on release of dopamine and serotonin in the striatum of spontaneously hypertensive rats: an in vivo voltammetric study (1984) (32)
Physiological and clinical chemistry of biopterin (1989) (32)
Endogenous synthesis of N-methylsalsolinol, an analogue of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, in rat brain during in vivo microdialysis with salsolinol, as demonstrated by gas chromatography-mass spectrometry. (1992) (32)
Organization and complete nucleotide sequence of the gene encoding mouse phenylethanolamine N-methyltransferase. (1992) (32)
Dopamine-stimulated adenylate cyclase activity in the human brain: changes in Parkinsonism. (1978) (32)
Inhibition of tyrosine hydroxylation in rat striatal tissue slices by 1-methyl-4-phenylpyridinium ion (1985) (31)
Comparative studies on the structure of human tyrosine hydroxylase with those of the enzyme of various mammals. (1991) (31)
Dopamine beta-hydroxylase activity in cerebrospinal fluid of Parkinsonian patients (1982) (31)
Aromatic L-amino acid decarboxylase activities in human lung tissues: comparison between normal lung and lung carcinomas. (1985) (31)
Purification of aromatic L-amino acid decarboxylase from bovine brain with a monoclonal antibody. (1988) (31)
Identification of 5-S- and 2-S-cysteinyldopamine and 5-S-glutathionyldopamine formed from dopamine by high-performance liquid chromatography with electrochemical detection (1986) (31)
Distribution of PZ-peptidase and glycylprolyl beta-naphthylamidase activities in oral tissues. (1975) (30)
Species differences of serum amino acid beta-napthylamidases. (1968) (30)
Highly Sensitive Assay for Dopamine‐β‐Hydroxylase Activity in Human Cerebrospinal Fluid by High Performance Liquid Chromatography‐Electrochemical Detection: Properties of the Enzyme (1981) (30)
Separation of Two Dipeptidyl Aminopeptidases in the Human Brain (1980) (30)
A simple assay of monoamine oxidase and D-amino acid oxidase by measuring ammonia. (1966) (30)
Detection of tetrahydroisoquinoline in parkinsonian brain as an endogenous amine by use of gas chromatography-mass spectrometry. (1989) (30)
Effects of nerve growth factor and nicotine on the expression of nicotinic acetylcholine receptor subunits in PC12 cells (1999) (30)
Effects of stereochemical structures of tetrahydrobiopterin on tyrosine hydroxylase. (1977) (30)
A radioassay for dopamine-β-hydroxylase activity in rat serum (1973) (29)
A sensitive and specific assay for dipeptidyl-aminopeptidase II in serum and tissues by liquid chromatography-fluorometry. (1985) (29)
Aromatic L-amino acid decarboxylase-immunoreactive neurons in and around the cerebrospinal fluid-contacting neurons of the central canal do not contain dopamine or serotonin in the mouse and rat spinal cord. (1988) (29)
Parkinsonism produced by tetrahydroisoquinoline (TIQ) or the analogues. (1993) (29)
Change of tyrosine hydroxylase in the parkinsonian brain and in the brain of MPTP-treated mice as revealed by homospecific activity (1990) (29)
A fluorometric determination of N-methyl-4-phenylpyridinium ion, using high-performance liquid chromatography. (1987) (29)
Effects of Systemic Administration of 1‐Methyl‐4‐Phenyl‐1,2,3,6‐Tetrahydropyridine to Mice on Tyrosine Hydroxylase, l‐3,4‐Dihydroxyphenylalanine Decarboxylase, Dopamine β‐Hydroxylase, and Monoamine Oxidase Activities in the Striatum and Hypothalamus (1988) (28)
Changes in monoamine levels in mouse brain elicited by forced-swimming stress, and the protective effect of a new monoamine oxidase inhibitor, RS-8359 (2005) (28)
Phenotypic changes of AADC-only immunopositive premammillary neurons in the brain of laboratory shrew Suncus murinus by systemic administration of monoamine precursors (1994) (28)
Simultaneous simple purification of tyrosine hydroxylase and dihydropteridine reductase. (1983) (28)
Striatal dopamine release and metabolism in sinoaortic-denervated rats by in vivo microdialysis. (1988) (28)
Catecholamine research : from molecular insights to clinical medicine (2002) (28)
Cerebral blood flow and freezing of gait in Parkinson's disease (2012) (28)
Inhibition of Monoamine Oxidase by N‐Methylisoquinolinium Ion (1987) (28)
Occurrence of a transcription factor, cAMP response element-binding protein (CREB), in the postsynaptic sites of the brain. (1998) (28)
A possible pathophysiological role of tyrosine hydroxylase in Parkinson’s disease suggested by postmortem brain biochemistry: a contribution for the special 70th birthday symposium in honor of Prof. Peter Riederer (2012) (27)
Excretion of X-prolyl dipeptidyl-aminopeptidase in human urine as determined with a new fluorogenic substrate. (1978) (27)
Selective release of serotonin by endogenous alkaloids, 1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolines, (R)- and (S)salsolinol, in the rat striatum; in vivo microdialysis study (1993) (27)
Immunohistochemical visualization of glutamate- and aspartate-containing nerve terminal pools in the rat limbic structures (1987) (27)
Effects of tyrosine administration on serum biopterin in normal controls and patients with Parkinson's disease. (1983) (27)
Radioimmunoassay for neopterin in body fluids and tissues. (1984) (27)
Changes in plasma tetrahydrobiopterin levels of depressives in depressive and remission phases: reconfirmed by measurement with an internal standard. (1994) (27)
Tetrahydrobiopterin-dependent production of l-DOPA in NRK fibroblasts transfected with tyrosine hydroxylase cDNA: future use for intracerebral grafting (1990) (27)
Prevention of dopaminergic neuron death by adeno-associated virus vector-mediated GDNF gene transfer in rat mesencephalic cells in vitro (1998) (27)
Enhancement or induction of neurite formation by a protein tyrosine phosphatase inhibitor, 3,4-dephostatin, in growth factor-treated PC12h cells. (1997) (27)
Fluorescence assay for dopamine beta-hydroxylase activity in human serum by high-performance liquid chromatography. (1977) (27)
Exogenous microglia enter the brain and migrate into ischaemic hippocampal lesions (1999) (27)
REGULATION OF TYROSINE HYDROXYLASE (1979) (27)
Reversible squamous cell characteristics induced by vitamin A deficiency in a small cell lung cancer cell line. (1987) (27)
Plasma norepinephrine in sleep apnea syndrome. (1986) (26)
Highly sensitive assay for gamma-glutamyltranspeptidase activity by high-performance liquid chromatography with electrochemical detection. (1986) (26)
Molecular mechanisms of hereditary progressive dystonia with marked diurnal fluctuation, Segawa's disease (2000) (26)
Immunocytochemical localization of GTP cyclohydrolase I in the brain, adrenal gland, and liver of mice (2005) (26)
Tyrosine hydroxylase in human adrenal glands and human pheochromocytoma. (1972) (26)
The 5'-flanking region of the human dopamine beta-hydroxylase gene promotes neuron subtype-specific gene expression in the central nervous system of transgenic mice. (1993) (26)
The mutation of two amino acid residues in the N‐terminus of tyrosine hydroxylase (TH) dramatically enhances the catalytic activity in neuroendocrine AtT‐20 cells (2002) (25)
Changes in the Concentrations of Tetrahydrobiopterin, the Cofactor of Tyrosine Hydroxylase, in Blood under Physical Stress and in Depression (2004) (25)
The activity of tyrosine hydroxylase and related enzymes of catecholamine biosynthesis and metabolism in dog kidney. Effects of denervation. (1969) (25)
Mechanism of antiinflammatory and antithermal burn action of CPase from Aloe arborescens Miller var. natalensis Berger in rats and mice (1993) (25)
Effect of peripherally administered lipopolysaccharide (LPS) on GTP cyclohydrolase I, tetrahydrobiopterin and norepinephrine in the locus coeruleus in mice (2007) (25)
Inhibition of tryptophan hydroxylase by (R)- and (S)-1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolines (salsolinols) (1992) (25)
β 2-microglobulin decrease in cerebrospinal fluid from parkinsonian patients (1989) (25)
Effects of Apomorphine on In Vivo Release of Dopamine and Its Metabolites in the Prefrontal Cortex and the Striatum, Studied by a Microdialysis Method (1989) (25)
Improved analysis for urinary polyamines by use of high-voltage electrophoresis on paper. (1980) (25)
Endogenous synthesis of N-methyl-1,2,3,4-tetrahydroisoquinoline, a precursor of N-methylisoquinolinium ion, in the brains of primates with parkinsonism after systemic administration of 1,2,3,4-tetrahydroisoquinoline. (1990) (25)
Effects of myosin light-chain kinase inhibitor on catecholamine secretion from rat pheochromocytoma PC12h cells. (1987) (24)
Tetrahydrobiopterin Administration for Parkinsonian Symptoms (1982) (24)
Catecholamine synthesis and release. Overview. (1998) (24)
Capsimycin, a new antibiotic. I. Production, isolation and properties. (1979) (24)
Partial separation and properties of tyrosine hydroxylase from the human pheochromocytoma: effect of norepinephrine. (1970) (24)
Stimulation of the Serotonin Autoreceptor Prevents the Calcium‐Calmodulin‐Dependent Increase of Serotonin Biosynthesis in Rat Raphe Slices (1986) (24)
Inactivation of tyrosine hydroxylase in rat striatum by 1-methyl-4-phenylpyridinium ion (MPP+) (1988) (23)
Activity of dipeptidyl peptidase IV and post-proline cleaving enzyme in sera from osteoporotic patients. (1988) (23)
Immunohistochemical colocalization of GTP cyclohydrolase I in the nigrostriatal system with tyrosine hydroxylase (1997) (23)
Regulation of oxidative stress in long‐lived lipopolysaccharide‐activated microglia (2012) (23)
4‐(O‐Benzylphenoxy)‐N‐Methylbutylamine (Bifemelane) and Other 4‐(O‐Benzylphenoxy)‐N‐Methylalkylamines as New Inhibitors of Type A and B Monoamine Oxidase (1988) (23)
INHIBITION OF DOPAMINE β-HYDROXYLASE BY AQUAYAMYCIN (1968) (23)
Structure of human phenylethanolamine n-methyltransferase gene: existence of two types of mRNA with different transcription initiation sites (1989) (23)
Tyrosine hydroxylation in the banana plant. (1972) (23)
Immunohistochemical study of small cell lung carcinoma; with special reference to the neuroendocrine markers aromatic L-amino acid decarboxylase and gastrin-releasing peptide. (1986) (23)
Nicotine regulates mRNA level of tyrosine hydroxylase gene but not that of nicotinic acetylcholine receptor genes in PC12 cells (1997) (23)
Inhibition of azoxymethane‐induced aberrant crypt foci formation in rat colorectum by whole leaf Aloe arborescens Miller var. natalensis berger (2001) (23)
Effects of structures of tetrahydropterin cofactors on rat brain tryptophan hydroxylase. (1980) (22)
Plasma tetrahydrobiopterin levels in patients with psychiatric disorders. (1990) (22)
Biosynthesis of tetrahydrobiopterin in parkinsonian human brain. (1987) (22)
Simple, sensitive assay of polyamines by high-performance liquid chromatography with electrochemical detection after post-column reaction with immobilized polyamine oxidase. (1989) (22)
Effects of melanin on tyrosine hydroxylase and phenylalanine hydroxylase. (1978) (22)
Determination of tetrahydrobiopterin in murine locus coeruleus by HPLC with fluorescence detection. (2001) (22)
Molecular Genetics of Hereditary Dystonia—Mutations in the GTP Cyclohydrolase I Gene (1997) (21)
A simple and sensitive fluorescence assay for tyrosine hydroxylase activity. (1979) (21)
Mouse sepiapterin reductase: an enzyme involved in the final step of tetrahydrobiopterin biosynthesis. Primary structure deduced from the cDNA sequence. (1995) (21)
Rotenone and CCCP inhibit tyrosine hydroxylation in rat striatal tissue slices. (2005) (21)
Dopamine-beta-hydroxylase and tyrosine hydroxylase activities in brain regions of rolling mouse nagoya. (1980) (21)
A sensitive assay of GTP cyclohydrolase I activity in rat and human tissues using radioimmunoassay of neopterin. (1986) (21)
The complete amino acid sequence of the mature form of rat sepiapterin reductase. (1990) (21)
Biochemical properties of carboxypeptidase from Aloe arborescens Miller var. natalensis Berger (1993) (21)
Specific Binding of Glycosylated β‐Galactosidase to Bovine Brain Synaptic Membrane (1986) (21)
Expression in brain sensory neurons of the transgene in transgenic mice carrying human tyrosine hydroxylase gene (1991) (21)
Highly sensitive, specific enzyme-linked immunosorbent assay of neopterin and biopterin in biological samples. (1992) (21)
Allosteric effect of tetrahydrobiopterin cofactors on tyrosine hydroxylase activity. (1992) (21)
Inhibition of type A monoamine oxidase by 1-methyl-4-phenylpyridine (1987) (21)
Reduction of enzyme activity of tyrosine hydroxylase and aromatic L-aminoacid decarboxylase in clonal pheochromocytoma PC12h cells by carcinogenic heterocyclic amines. (1988) (21)
Effect of N‐Methyl‐4‐Phenylpyridinium Ion on Monoamine Oxidase in a Clonal Rat Pheochromocytoma Cell Line, PC 12h (1987) (21)
IL-1 beta and TNF-alpha suppress apolipoprotein (apo) E secretion and apo A-I expression in HepG2 cells. (1998) (20)
Complex Formation of Chlorpromazine with Flavins (1959) (20)
Post-proline cleaving enzyme in human cerebrospinal fluid from control patients and parkinsonian patients. (1987) (20)
Application of high-performance liquid chromatography to the study of biogenic amine-related enzymes. (1991) (20)
Migration of injected C14-labelled riboflavin into rat tissues. (1966) (20)
Highly sensitive assay for phenylethanolamine N-methyltransferase activity in rat brain by high-performance liquid chromatography with electrochemical detection. (1982) (20)
Reduced tyrosine hydroxylase activity in nigrostriatal system of sinoaortic-denervated rats (1984) (20)
A simple assay of dopamine beta-hydroxylase activity in the homogenate of the adrenal medulla. (1969) (20)
Tryptophan hydroxylase system in brain tissue slices assayed by high-performance liquid chromatography (1983) (20)
Norepinephrine-synthesizing enzymes in brain, adrenals and peripheral sympathetic nerves of spontaneously hypertensive rats. (1977) (20)
Purification and immunochemical characterization of human adrenal tyrosine hydroxylase (1984) (20)
Specific localization of the guanosine triphosphate (GTP) cyclohydrolase I-immunoreactivity in the human brain (1999) (19)
New and highly sensitive assay for L-5-hydroxytryptophan decarboxylase activity by high-performance liquid chromatography-voltammetry. (1980) (19)
Expression of two forms of human dopamine-β-hydroxylase in COS cells (1991) (19)
Increase of transcriptional levels of egr-1 and nur77 genes due to both nicotine treatment and withdrawal in pheochromocytoma cells (2002) (19)
Application of electrochemical detection in high-performance liquid chromatography to the assay of biologically active compounds (1988) (18)
The human tyrosine hydroxylase gene (1989) (18)
Tyrosine hydroxylase indicates cell differentiation of catecholamine biosynthesis in neuroendocrine tumors (1994) (18)
Glycylprolyl beta-naphthylamidase activities in serum, liver and kidney of rats in chronic carbon tetrachloride intoxication. (1976) (18)
The relationship between depression and regional cerebral blood flow in Parkinson’s disease and the effect of selegiline treatment (2011) (18)
Comparison of human serum dopamine-beta-hydroxylase levels by radioimmunoassay and enzymatic assay. (1974) (18)
Expression of A and B types of monoamine oxidase in neuroblastoma hybrid cells (1981) (18)
Dopamine-β-hydroxylase in blood and cerebrospinal fluid (1977) (18)
Increase of Catecholamines in Mouse Brain by Systemic Administration of γ‐Glutamyl L‐3,4‐Dihydroxyphenylalanine (1987) (18)
OCCURRENCE OF A SEROTONIN SULPHOTRANSFERASE IN THE BRAIN (1969) (18)
Inhibition of type A and B monoamine oxidase by 6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolines and their N-methylated derivatives (2005) (18)
Simultaneous determination of guanine nucleotides in rat brain by high-performance liquid chromatography with dual-electrochemical detection. (1984) (18)
Functionally important residues tyrosine-171 and serine-158 in sepiapterin reductase. (1999) (18)
Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration in prenatal stage on the dopamine system in the postnatal mouse brain. (1991) (18)
Effect of 1-methyl-4-phenylpyridinium ion (MPP+) on catecholamine levels and activity of related enzymes in clonal rat pheochromocytoma PC12h cells. (1988) (18)
Purification and immunochemical properties of tyrosine hydroxylase in human brain (1986) (17)
Dopa-producing astrocytes generated by adenoviral transduction of human tyrosine hydroxylase gene: in vitro study and transplantation to hemiparkinsonian model rats (1999) (17)
Interconversion of biological characteristics of small cell lung cancer depending on culture conditions. (1984) (17)
Separation of two PZ-peptidases from bovine dental follicle. (1976) (17)
Effects of stereochemical structures of tetrahydropterins on tyrosine hydroxylase. (1975) (17)
Nucleotide sequence of Suncus murinus immunoglobulin μ gene and comparison with mouse and human μ genes (1989) (17)
Parkinson's Disease: From Basic Research to Treatment (1993) (17)
Enzymes related to catecholamine biosynthesis in Tetrahymena pyriformis. Presence of GTP cyclohydrolase I. (1998) (17)
Inhibition of aromatic L-aminoacid decarboxylase in clonal pheochromocytoma PC12h cells by N-methyl-4-phenylpyridinium ion (MPP+). (1988) (17)
Antibodies raised against different oligopeptide segments of human dopamine-β-hydroxylase (1990) (17)
Selective removal of beta 2-microglobulin from human plasma by high-performance immunoaffinity chromatography. (1989) (17)
Microglial Activation in Neuroinflammation: Implications for the Etiology of Neurodegeneration (2012) (17)
Immunocytochemical study of catecholaminergic neurons in the senescence-accelerated mouse (SAM-P8) brain (2005) (17)
Chemical features of monoaminergic and non-monoaminergic neurons in the brain of laboratory shrew (Suncus murinus) are changed by systemic administration of monoamine precursors (1995) (17)
Adrenal tyrosine hydroxylase and dopamine beta-hydroxylase in spontaneously hypertensive rats. (1971) (16)
Increment of α B-crystallin mRNA in the brain of patient with infantile type Alexander's disease (1991) (16)
Inhibition of deubiquitinating activity of USP14 decreases tyrosine hydroxylase phosphorylated at Ser19 in PC12D cells. (2016) (16)
Neural degeneration in Parkinson's disease. (2001) (16)
Studies on the regulatory mechanism of the tyrosine hydroxylase system in adrenal slices by using high-performance liquid chromatography with electrochemical detection. (1982) (16)
Genomic organization and chromosomal localization of the human sepiapterin reductase gene. (1998) (16)
Presence of tetrahydroisoquinoline-related compounds, possible MPTP-like neurotoxins, in parkinsonian brain. (1993) (16)
Effects of structures of tetrahydropterin cofactors on tyrosine hydroxylase. (1980) (16)
Characterization of four new cell lines derived from small‐cell gastrointestinal carcinoma (1993) (16)
Monoamine oxidase : basic and clinical frontiers : proceedings of a symposium held in Hakone, Japan, July 25-27, 1981 (1982) (16)
Enhanced expression of GTP cyclohydrolase I in V-1-overexpressing PC12D cells. (2002) (16)
Peripherally administered (6R)-tetrahydrobiopterin increases in vivo tyrosine hydroxylase activity in the striatum measured by microdialysis both in normal mice and in transgenic mice carrying human tyrosine hydroxylase (1994) (16)
Alteration of Catecholamine Phenotype in Transgenic Mice Influences Expression of Adrenergic Receptor Subtypes (1995) (16)
A sensitive fluorometric assay for monoamine oxidase activity. (1973) (16)
Total biopterin levels of plasma in patients with depression. (1987) (16)
Formation of serotonin O-sulfate by sulfotransferase of rabbit liver. (1969) (16)
Sandwich enzyme-immunoassay for dipeptidyl aminopeptidase IV in the serum of people with oral cancer. (1986) (16)
Biopterin cofactor and regulation of monoamine-synthesizing mono-oxygenases (1981) (15)
Neuromelanin in Parkinson’s Disease: Tyrosine Hydroxylase and Tyrosinase (2022) (15)
Metabolic Bioactivation of Endogenous Isoquinolines as Dopaminergic Neurotoxins to Elicit Parkinson’s Disease (1995) (15)
GTP cyclohydrolase I activity in mononuclear blood cells in juvenile parkinsonism (1995) (15)
Normalization of tyrosine hydroxylase activity in vivo in the striatum of transgenic mice carrying human tyrosine hydroxylase gene: a microdialysis study (1993) (15)
Arylaminopeptidase activities in human cariogenic and non-cariogenic oral bacteria. (1971) (15)
Atypical adult GM1 gangliosidosis (1986) (15)
Monoaminergic neurons in the brain of goldfish as observed by immunohistochemical techniques (1983) (15)
Effects of atypical antipsychotics and haloperidol on PC12 cells: only aripiprazole phosphorylates AMP-activated protein kinase (2010) (15)
Establishment of a Human Small Cell Lung Cancer Cell Line Producing a Large Amount of Anti‐diuretic Hormone (1994) (15)
Inhibitory action of proline-containing peptides on Xaa-Pro-dipeptidylaminopeptidase. (1982) (15)
Changes in serum dipeptidyl-aminopeptidase IV (glycylprolyl dipeptidyl-aminopeptidase) activity of patients with gastric carcinoma after surgical excision and the enzyme activity in the carcinoma tissue. (1981) (15)
The L-DOPA story - an early Japanese contribution (2000) (15)
Dipeptidyl-aminopeptidase II in human cerebrospinal fluid: changes in patients with Parkinson's disease. (1987) (15)
Effects of dopamine on N-terminus-deleted human tyrosine hydroxylase type 1 expressed in Escherichia coli (1997) (15)
Purification and properties of human brain mitochondrial monoamine oxidase. (1970) (15)
A new splicing variant for human tyrosine hydroxylase in the adrenal medulla (2001) (15)
Receptor‐associated changes of the catecholamine‐sensitive adenylate cyclase in glioma cells doubly transformed with Moloney sarcoma virus (1982) (15)
Quinolinic acid: an endogenous inhibitor specific for type B monoamine oxidase in human brain synaptosomes (1987) (15)
Characterization of the human NTAK gene structure and distribution of the isoforms for rat NTAK mRNA. (2000) (15)
Inhibition of tryptophan hydroxylase by food-derived carcinogenic heterocyclic amines, 3-amino-1-methyl-5H-pyrido[4,3-b]indole and 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole. (1991) (15)
The bipotential glial progenitor cell line can develop into both oligodendrocytes and astrocytes in the mouse forebrain (1995) (15)
GTP cydohydrolase I gene, dystonia, juvenile parkinsonism, and Parkinson’s disease (1997) (15)
The relationship between collagen metabolism and temporomandibular joint osteoarthrosis in mice. (1993) (15)
INCORPORATION OF PERIPHERALLY ADMINISTERED RIBOFLAVINE INTO FLAVINE NUCLEOTIDES IN THE BRAIN (1967) (15)
Prolyl oligopeptidase and dipeptidyl peptidase II/dipeptidyl peptidase IV ratio in the cerebrospinal fluid in Parkinson’s disease: historical overview and future prospects (2017) (14)
Short-term effect of stress on tyrosine hydroxylase activity (1982) (14)
Inhibition of inflammatory cytokine secretion from mouse microglia cells by DHMEQ, an NF-kappaB inhibitor. (2005) (14)
Acute effects of 1-methyl-4-phenylpyridinium ion (MPP+) on dopamine and serotonin metabolism in rat striatum as assayed in vivo by a micro-dialysis technique (2005) (14)
Limited proteolysis of tyrosine hydroxylase by Ca(2+)-activated neutral protease (calpain). (1991) (14)
Inactivation of serotonin by sulfotransferase system. (1969) (14)
Characterization of neuron-specific huntingtin aggregates in human huntingtin knock-in mice (2007) (14)
Elevated levels of oncopterin, N2-(3-aminopropyl)biopterin, a new pterin compound, in urine from patients with solid and blood cancers. (1993) (14)
Positive charge intrinsic to Arg37‐Arg38 is critical for dopamine inhibition of the catalytic activity of human tyrosine hydroxylase type 1 (2000) (14)
Purification and properties of an amine oxidase in bovine dental pulp and its comparison with serum amine oxidase. (1974) (14)
Tryptophan hydroxylase activity in the brains of controls and parkinsonian patients (2005) (14)
Effect of 7-(3-[4-(2,3-dimethylphenyl)piperazinyl]propoxy)- 2(1H)-quinolinone (OPC-4392), a newly synthesized agonist for presynaptic dopamine D2 receptor, on tyrosine hydroxylation in rat striatal slices. (1988) (14)
Round Table on: IS THERE DOPA DECARBOXYLASE IN HUMAN BRAIN? (1979) (14)
Uptake of heterocyclic amines, Trp-P-1 and Trp-P-2, into clonal rat pheochromocytoma PC12h cells by dopamine uptake system (1989) (14)
Activation of tyrosine hydroxylase by Ca2+-dependent neutral protease, calpain. (1986) (14)
3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2) and other heterocyclic amines as inhibitors of mitochondrial monoamine oxidases separated from human brain synaptosomes (1990) (14)
Lipopolysaccharide extends the lifespan of mouse primary-cultured microglia (2009) (14)
Relation between Nucleolar Size and Growth Characteristics in Small Cell Lung Cancer Cell Lines (1991) (14)
In vivo microdialysis of neurotransmitters and their metabolites (1993) (13)
Sensitive assay for determination of pyridoxal-5-phosphate in enzymes using high-performance liquid chromatography after derivatization with cyanide. (1988) (13)
Decrease in GTP cyclohydrolase I gene expression caused by inactivation of one allele in hereditary progressive dystonia with marked diurnal fluctuation. (1999) (13)
Studies on substrate specificity of X-prolyl dipeptidyl-aminopeptidase using new chromogenic substrates, X-Y-p-nitroanilides (1978) (13)
Incorporation of Glycosylated β‐Galactosidase into Bovine Brain Synaptosomes (1986) (13)
RNAi of 14-3-3eta protein increases intracellular stability of tyrosine hydroxylase. (2007) (13)
Arylaminopeptidase activities in bovine dental pulp. (1972) (13)
Normal values and age-dependent changes in GTP cyclohydrolase I activity in stimulated mononuclear blood cells measured by high-performance liquid chromatography. (2000) (13)
Effect of the 1-methyl-4-phenylpyridinium ion on phosphorylation of tyrosine hydroxylase in rat pheochromocytoma PC12h cells (1988) (13)
Tetrahydrobiopterin Biosynthesis Enhanced by Lipopolysaccharide Stimulation in Murine Neuroblastoma Cell Line N1E‐115 (1996) (13)
Sandwich enzyme immunoassay of dopamine-β-hydroxylase in cerebrospinal fluid from control and parkinsonian patients (1988) (13)
Ganglioside GM1 Causes Expression of Type B Monoamine Oxidase in a Rat Clonal Pheochromocytoma Cell Line, PC12h (1987) (13)
Purification and characterization of human liver beta-galactosidase from a patient with the adult form of GM1 gangliosidosis and a normal control. (1988) (13)
Hydrolysis of amino acidβ-naphthylamides by aminopeptidases in human parotid saliva and human serum (1968) (13)
On the mechanism of inhibition of dopamine-beta-oxidase by benzyloxyamines. (1963) (13)
Purification and properties of dipeptidyl peptidase IV from human urine. (1990) (13)
Monoamine oxidase activities towards biogenic monoamines in several regions of rat brain (1975) (13)
Formation of serotonin O-sulfate by rat liver sulfating system. (1966) (13)
Serum glyccylproline p-nitroanilidase activity in human hypertension. (1977) (12)
Direct imaging of phosphorylation‐dependent conformational change and DNA binding of CREB by electron microscopy (2000) (12)
Alterations in multiple tyrosine hydroxylase mRNAs in the substantia nigra, locus coeruleus and adrenal gland of MPTP-treated parkinsonian monkeys. (1995) (12)
Autonomic neuropathy in transgenic mice caused by immunotoxin targeting of the peripheral nervous system (1998) (12)
NTAKα and β Isoforms Stimulate Breast Tumor Cell Growth by Means of Different Receptor Combinations (2000) (12)
Deletion mutagenesis of human tyrosine hydroxylase type 1 regulatory domain. (1995) (12)
Stress-induced changes in in vivo and in vitro dopamine-β-hydroxylase activity in spontaneously hypertensive rats (1982) (12)
Transient appearance of tyrosine hydroxylase-immunoreactive non-catecholaminergic neurons in the medial geniculate nucleus of postnatal mice (1996) (12)
Determination of aromatic L-amino acid decarboxylase in serum of various animals by high-performance liquid chromatography with electrochemical detection. (1981) (12)
Highly sensitive assay for alkaline and acid phosphatase activities by high-performance liquid chromatography with electrochemical detection. (1987) (12)
Studies on the uptake of N-methylisoquinolinium ion into rat striatal slices using high-performance liquid chromatography with fluorimetric detection. (1990) (12)
Pteridines as cofactor or inhibitor of tyrosine hydroxylase. (1972) (12)
PROPERTIES OF TYROSINE HYDROXYLASE IN PERIPHERAL NERVES (1975) (12)
Effect of long-term administration of 1,2,3,4-tetrahydroisoquinoline (TIQ) on striatal dopamine and 3,4-dihydroxyphenylacetic acid (DOPAC) content in mice (1988) (12)
Phenylethanolamine-N-methyltransferase – immunoreactive nerve terminals afferent to the mouse substantia nigra (1998) (12)
Presence of leucine aminopeptidase activity in human saliva from the parotid gland and the submaxillary-sublingual glands. (1968) (12)
GTP cyclohydrolase I gene, tetrahydrobiopterin, and tysorine hydroxylase gene: Their relations to dystonia and parkinsonism (1996) (12)
High performance liquid chromatography of biological polyamines using immobilized enzyme as post-column reactor followed by electrochemical detection. (1989) (12)
Age-associated changes in the dopamine synthesis as determined by GTP cyclohydrolase I inhibitor in the brain of senescence-accelerated mouse-prone inbred strains (SAMP8) (1999) (12)
Inhibition of Type A Monoamine Oxidase by Methylquinolines and Structurally Related Compounds (1988) (12)
IMMUNOHISTOCYTOCHEMICAL LOCALIZATION OF TYROSINE HYDROXYLASE AND SEROTONIN IN THE BRAIN OF GOLDEN HAMSTER (1982) (12)
Reduction of enzymatic activity of tyrosine hydroxylase by a heterocyclic amine, 3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole (Trp-P-1), was due to reduced affinity to a cofactor biopterin (1991) (11)
This section of the Journal is devoted to rapidly published one page research notes (See Instructions to Authors, 49:895, July-August 1970.) Catecholamines in the Dental Pulp (1970) (11)
Peripheral Lipopolysaccharide Administration Affects the Olfactory Dopamine System in Mice (2008) (11)
Nicotine withdrawal up-regulates c-Fos transcription in pheochromocytoma cells (1999) (11)
Deletion of N‐terminus of human tyrosine hydroxylase type 1 enhances stability of the enzyme in AtT‐20 cells (2005) (11)
Uptake of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and the N-methyl-4-phenylpyridinium ion (MPP+) into fetal mouse brain through the placenta (1989) (11)
Plasma biopterin levels of patients with affective disorders. (1988) (11)
Inhibition of human brain aromatic l-amino acid decarboxylase by cooked food-derived 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2) and other heterocyclic amines (1990) (11)
L-threo-3,4-dihydroxyphenylserine (DOPS) aldolase: a new enzyme cleaving DOPS into protocatechualdehyde and glycine. (1987) (11)
Origin of Cyclic Adenosine Monophosphate in Saliva (1975) (11)
Tyrosine hydroxylase (TH)-only-immunoreactive non-catecholaminergic neurons in the brain of wild mice or the human TH transgenic mice do not contain GTP cyclohydrolase I (1997) (11)
Changes of tyrosine hydroxylase in parkinsonian brains and in the brains of MPTP-treated mice. (1990) (11)
Simple and sensitive assay of dopamine β-hydroxylase in human cerebrospinal fluid by high-performance liquid chromatography with electrochemical detection (1985) (11)
Purification and properties of amine oxidases in brain and connective tissue (dental pulp). (1972) (11)
Inhibition of dopamine beta-hydroxylase by fusaric acid (5-butylpicolinic acid) in vitro and in vivo. (1970) (11)
Partial separation and properties of mitochondrial monoamine oxidase in brain. (1966) (11)
HISTOCHEMICAL AND BIOCHEMICAL CHARACTERIZATION OF THE BULLFROG LUMBAR SYMPATHETIC GANGLIA AND SCIATIC NERVES (1979) (11)
Inhibition of N-ethyl-N'-nitro-N-nitrosoguanidine-induced Duodenal Tumorigenesis in Mice by Whole-leaf Aloe arborescens Miller var. natalensis Berger. (2000) (11)
Dental Sac Collagenase: Demonstration and Initial Characterization (1978) (11)
cGMP inhibits GTP cyclohydrolase I activity and biosynthesis of tetrahydrobiopterin in human umbilical vein endothelial cells. (2003) (10)
Neuroprotective and Neurotoxic Phenotypes of Activated Microglia in Neonatal Mice with Respective MPTP- and Ethanol-Induced Brain Injury (2010) (10)
Endogenous inhibitors of DOPA decarboxylase in rat submandibular gland. (1980) (10)
3,4-dihydroxystyrene, a novel microbial inhibitor for phenylalanine hydroxylase and other pteridine-dependent monooxygenases. (1984) (10)
Metabolism of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in a rat pheochromocytoma cell line, PC12h. (1987) (10)
Inhibition of monoamine oxidase by 3,4-dihydroxyphenyl L-alanine and its analogues. (1987) (10)
Rapid chromatographic purification of dipeptidyl-aminopeptidase II from human kidney. (1987) (10)
Electronic and Conformational Effects on the Lipophilicity of Isomers and Analogs of the Neurotoxin 1‐Methyl‐4‐phenylpyridinium (MPP+) (1991) (10)
IMMUNOHISTOCYTOCHEMICAL DISTRIBUTION OF AMINE-CONTAINING NEURONS RELATED TO CIRCUMVENTRICULAR ORGANS IN THE FROG BRAIN (1982) (10)
Intracellular stability of tyrosine hydroxylase: phosphorylation and proteasomal digestion of the enzyme. (2013) (10)
[7] Tyrosine 3-monooxygenase from bovine adrenal medulla (1987) (10)
Uptake of N-methyl-4-phenylpyridinium ion (MPP+) into PC12h pheochromocytoma cells (1987) (10)
A novel strategy for the negative selection in mouse embryonic stem cells operated with immunotoxin-mediated cell targeting. (1996) (10)
GTP cyclohydrolase I gene, dystonia, juvenile parkinsonism, and Parkinson's disease. (1997) (10)
Endogenous synthesis of N-methylnorsalsolinol in rat brain during in vivo microdialysis with epinine. (1994) (10)
The Presence of Substance P Carboxy-Terminal Heptapeptide in Pig Brain Stem (1980) (10)
Concentrations of neopterin and biopterin in serum from patients with rheumatoid arthritis or systemic lupus erythematosus and in synovial fluid from patients with rheumatoid or osteoarthritis. (1990) (10)
Occurrence of umanopterin, a new diastereomer of neopterin, in urine from cancer patients (1992) (10)
METHYLSPINAZARIN AND DIHYDROMETHYLSPINAZARIN, GATEGHOL-O-METHYL TRANSFERASE INHIBITORS PRODUCED BY STREPTOMYCES (1973) (10)
Identification and Characterization of a Novel Phorbol Ester-responsive DNA Sequence in the 5′-Flanking Region of the Human Dopamine β-Hydroxylase Gene* (1998) (10)
Purification and Properties of Bovine Brain Dopamine β‐Hydroxylase (1982) (10)
Ferrous ion activates the less active form of human adrenal tyrosine hydroxylase (1990) (10)
Simultaneous determination of N2-(3-aminopropyl)biopterin (oncopterin), biopterin and neopterin by high-performance liquid chromatography with fluorescence detection. (1995) (10)
Coexistence of tyrosine hydroxylase and serotonin in the raphe nucleus of the laboratory shrew (Suncus murinus) during postnatal life. (1997) (10)
Factors influencing dopamine beta-hydroxylase activity and epinephrine levels in guinea pig adrenal gland. (1968) (10)
An integrated scheme for the simultaneous determination of biogenic amines, precursor amino acids, and related metabolites by liquid chromatography with electrochemical detection. (1984) (9)
A rapid and simple assay of serotonin sulfokinase activity. (1967) (9)
Biochemical aspects of Parkinson's disease. (1993) (9)
Localization of sepiapterin reductase in the human brain (2002) (9)
Studies on Biologically Active Pteridines. IV. Synthesis of Several Biopterin Derivatives as an Antigen in Radioimmunoassay for Biopterin (1980) (9)
Effects of heterocyclic amines in food on dopamine metabolism in nigro-striatal dopaminergic neurons. (1988) (9)
Polarization fluoroimmunoassay of biopterin and neopterin in human urine. (1984) (9)
Effects of aripiprazole and clozapine on the treatment of glycolytic carbon in PC12 cells (2012) (9)
Identification of (6R)‐5,6,7,8‐Tetrahydro‐D‐monapterin (=(6R)‐2‐Amino‐5,6,7,8‐tetrahydro‐6‐[(1R,2R)‐1,2,3 ‐trihydroxypropyl]pteridin‐4(3H)‐one) as the Native Pteridine in Tetrahymena pyriformis (2001) (9)
Determination of oncopterin isolated from urine of cancer patients as N2-(3-aminopropyl)biopterin (1992) (9)
Ontogenesis of Monoamine‐Synthesizing Enzyme Activities and Biopterin Levels in Rat Brain or Salivary Glands, and the Effect of Thyroxine Administration (1982) (9)
The effect of flavin adenine dinucleotide on the electroencephalogram modified by chlorpromazine (1960) (9)
CATECHOLAMINE-RELATED ENZYMES IN THE BRAIN OF PARKINSONIAN PATIENTS (1979) (9)
A convenient determination of chiral pteridines; application of fluorescence detected circular dichroism (FDCD) to the major pterin from Escherichia coli (2001) (9)
Immunohistochemical Localization Of Catecholamine Synthesizing Enzymes In Bullfrog Adrenals (1979) (9)
Comparison of X-prolyl dipeptidyl-aminopeptidase activity in human cerebrospinal fluid with that in serum (1979) (9)
Cytotoxic effect of 1-methyl-4-phenylpyridinium ion on human melanoma cell lines, HMV-II and SK-MEL-44, is dependent on the melanin contents and caused by inhibition of mitochondrial electron transport. (1990) (9)
Gas chromatography of catecholamines and related compounds. (1966) (9)
Identification by nano-LC-MS/MS of NT5DC2 as a protein binding to tyrosine hydroxylase: Down-regulation of NT5DC2 by siRNA increases catecholamine synthesis in PC12D cells. (2019) (9)
Inhibition of type a monoamine oxidase by N-methyl β-carbolinium ions (1995) (9)
Existence of noradrenalin cells and serotonin cells in the pituitary gland of Rana catesbeiana (2004) (9)
Expression of human tyrosine hydroxylase type I in Escherichia coli as a protease-cleavable fusion protein (1999) (9)
Prolyl hydroxylase activity in human normal skins and post-burn scars. (1977) (8)
Phenylethanolamine N-methyltransferase activity in human brains. (1982) (8)
MPTP and its relevance to parkinson's disease (1987) (8)
Distribution of β 1- and β 2-adrenoceptor subtypes in various mouse tissues (1993) (8)
MULTIPLE FORMS OF GLYCYLPROLYL DIPEPTIDYL AMINOPEPTIDASE (DIPEPTIDYL PEPTIDASE IV) IN HUMAN SERA FROM PATIENTS WITH HEPATITIS (1982) (8)
Cyclosporin A, an immune suppressor, enhanced neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to mice (1989) (8)
Lysyl oxidase activity in human normal skins and postburn scars. (1976) (8)
Expression of mouse tyrosine hydroxylase in Escherichia coli. (1991) (8)
Increase of urinary putrescine in 3,4-benzopyrene carcinogenesis and its inhibition by putrescine. (1978) (8)
Regulatory mechanism of dopamine biosynthesis in the striatum of transgenic mice carrying human tyrosine hydroxylase gene (1993) (8)
Exon 3 of tyrosine hydroxylase gene: lack of association with Japanese schizophrenic patients (2001) (8)
A sensitive fluorometric assay for dopamine-beta-hydroxylase activity by high-performance liquid chromatography. (1984) (8)
Micro-determination of monoamine oxidase using serotonin as substrate. (1967) (8)
Detection of 1-phenyl-N-methyl-1,2,3,4-tetrahydroisoquinoline and 1-phenyl-1,2,3,4-tetrahydroisoquinoline in human brain by gas chromatography-tandem mass spectrometry. (1995) (8)
Catecholaminergic Enzymes in Parkinson’s Disease and Related Extrapyramidal Diseases (1981) (8)
Food-derived heterocyclic amines, 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole and related amines, as inhibitors of monoamine metabolism. (1994) (8)
Tyrosine hydroxylase, tryptophan hydroxylase, and the biopterin cofactor in the brains from patients with Alzheimer's disease (1989) (8)
Presence of N-methyldopamine in parkinsonian and normal human brains. (1993) (8)
Activity of dipeptidyl peptidase II and dipeptidyl peptidase IV in human gingiva with chronic marginal periodontitis. (1990) (8)
Excretion of Cyclic GMP and Cyclic AMP into Human Parotid Saliva (1974) (8)
Effect of short-term swimming stress and diazepam on 3,4-dihydroxyphenylacetic acid (DOPAC) and 5-hydroxyindoleacetic acid (5-HIAA) levels in the caudate nucleus: an in vivo voltammetric study (1985) (8)
Studies on the genotype-phenotype relation in the hph-1 mouse mutant deficient in guanosine triphosphate (GTP) cyclohydrolase I activity (2000) (8)
Serotonin in neuroblastoma × glioma NG108-15 hybrid cells (1983) (8)
ADRENAL PHEOCHROMOCYTOMA WITH BOTH BENIGN AND MALIGNANT COMPONENTS (1976) (8)
The activity of dipeptidyl peptidase II and dipeptidyl peptidase IV in mice immunized with type II collagen. (1992) (7)
Polyamine levels of urine and erythrocytes on inhibition of DMBA-induced oral carcinogenesis by topical beta-carotene (1990) (7)
Tyrosine hydroxylase and tryptophan hydroxylase activities and its cofactor biopterin level in brain regions of the rolling mouse: The influence of thyrotropin releasing hormone (1982) (7)
Isolation of a full-length cDNA clone for human GTP cyclohydrolase I type 1 from pheochromocytoma (2005) (7)
24-hour rhythm of human plasma noradrenaline and the effect of fusaric acid, a dopamine-beta-hydroxylase inhibitor. (1980) (7)
Aromatic-L-aminoacid decarboxylase-immunoreactive cerebrospinal fluid-contacting neurons do not contain dopamine and serotonin in the mouse and rat spinal central canals (1988) (7)
Effects of subacute administration of methamphetamine and nicotine on locomotor activity in transgenic mice expressing the human tyrosine hydroxylase gene (2005) (7)
Expression of human tyrosine hydroxylase-chloramphenicol acetyltransferase (CAT) fusion gene in the brains of transgenic mice as examined by CAT immunocytochemistry (2005) (7)
Serum dopamine beta-hydroxylase activity in developing hypertensive rats. (1974) (7)
Diastereomers of neopterin and biopterin in human urine. (1992) (7)
Interference of a methotrexate derivative with urinary oncopterin [N2-(3-aminopropyl)biopterin] measurement by high-performance liquid chromatography with fluorimetric detection. (1997) (7)
Molecular and physiological properties of tyrosine hydroxylase induced by reserpine in rat adrenal gland. (1985) (7)
1,4-benzoquinone as a new inhibitor of monoamine oxidase (1987) (7)
Collagenase-like (CL) peptidase activity in synovial fluid from patients with rheumatoid arthritis. (1987) (7)
Aripiprazole increases NADPH level in PC12 cells: the role of NADPH oxidase (2013) (7)
Dopamine β-Hydroxylase Activity in Stroke-prone Spontaneously Hypertensive Rats (1978) (7)
Dopamineβ-hydroxylase and tyrosine hydroxylase activities in spontaneously hypertensive rats after NaCl administration (1975) (7)
Inhibition of hepatocellular carcinoma development and erythrocyte polyamine levels in ODS rats fed on 3'-methyl-4-dimethylaminoazobenzene by hemicalcium ascorbate, 2-O-octadecylascorbic acid, and ascorbyl palmitate. (1996) (7)
Effect of lipopolysaccharide on the gene expression of the enzymes involved in tetrahydrobiopterin de novo biosynthesis in murine neuroblastoma cell line N1E-115 (1997) (7)
Intracerebrally administered (6r)-l-erythro-tetrahydrobiopterin does not affect extracellular levels of dopamine and serotonin metabolites in rat striatum in vivo during measurement by brain micro-dialysis system (1988) (7)
Right-left asymmetry of tyrosine hydroxylase in rat median eminence: influence of arterial baroreflex nerves (1990) (7)
Increment of alpha B-crystallin mRNA in the brain of patient with infantile type Alexander's disease. (1991) (7)
D-neurons (TH-negative, AADC-positive neurons) may belong to APUD system in the laboratory shrew (Suncus murinus) brain (1994) (7)
Inhibition of phenylalanine hydroxylase, a pterin-requiring monooxygenase, by oudenone and its derivatives. (1982) (7)
Isolation and Characterization of a cDNA Clone Encoding Human Aromatic L-Amino Acid Decarboxylase (1991) (7)
An integrated scheme for the simultaneous determination of biogenic amines, precursor amino acids, and related metabolites by liquid chromatography with electrochemical detection (1998) (7)
Correlation between X-prolyl dipeptidyl-aminopeptidase and serum amine oxidase in serum of patients with post-burn keloids. (1979) (6)
Condensation Products of Ethylenediamine with Adrenaline (1959) (6)
Changes of X-prolyl dipeptidyl-aminopeptidase activity in developing rat brain (1979) (6)
CONDENSATION PRODUCTS OF ETHYLENEDIAMINE WITH CATECHOL DERIVATIVES (1960) (6)
Sulfhydryl modification and activation of phenylalanine hydroxylase by dinitrophenyl alkyl disulfide. (1987) (6)
Effect of (6R)- and (6S)-tetrahydrobiopterin on L-3,4-dihydroxyphenylalanine (DOPA) formation in NRK fibroblasts transfected with human tyrosine hydroxylase type 2 cDNA (1990) (6)
Serum dopamine-beta-hydroxylase in schizophrenic patients. (1978) (6)
Dopamine beta-hydroxylase activity in human cerebrospinal fluid from various age groups. (1982) (6)
Expression of two forms of human dopamine-beta-hydroxylase in COS cells. (1991) (6)
Purification of phenylalanine hydroxylase from human adult and foetal livers with a monoclonal antibody. (1985) (6)
Radioimmunoassay for Biopterin (1979) (6)
Changes in activities of tryptophan hydroxylase and cyclic AMP-dependent and calcium-calmodulin-dependent protein kinases in raphe serotonergic neurons of 5,7-dihydroxytryptamine-treated rats (1985) (6)
Peripherally injected lipopolysaccharide induces apoptosis in the subventricular zone of young adult mice (2010) (6)
Studies on Biologically Active Pteridines. II. Synthesis of Some 2-Pyrimidinyl- and 2-Pteridinyl-amino Acids (1979) (6)
Preparation and Cofactor Activity of (6S)-Tetrahydrobiopterin (I). (1986) (6)
A sensitive and inexpensive high-performance liquid chromatographic assay for tyrosine hydroxylase (2005) (6)
Nicotine-induced regulation of tyrosine hydroxylase activity in adrenal gland of transgenic mouse carrying human tyrosine hydroxylase gene (1994) (6)
Immunofluorescent and biochemical studies on tyrosine hydroxylase and dopamine-β-hydroxylase of the bullfrog sciatic nerves (1979) (6)
Simple photometric assay of dopamine-beta-hydroxylase activity in human blood: useful in clinical chemistry. (2009) (6)
The role of L-aromatic amino acid decarboxylase in serotonin-stimulated aldosterone secretion in response to salt intake. (1996) (6)
Inhibition of dopamine-beta-hydroxylase by spinochrome A and echinochrome A, naphthoquinone pigments of echinoids. (1973) (6)
Reduction of aromatic l-amino acid decarboxylase activity in clonal pheochromocytoma PC12h cells by culture in the presence of N-methyl-4-phenylpyridinium ion (MPP+) (1988) (6)
NTAKalpha and beta isoforms stimulate breast tumor cell growth by means of different receptor combinations. (2000) (6)
Enzymes of Catecholamine Biosynthesis and Metabolism in Spontaneously Hypertensive Rats and Hypotensive Effects of the Specific Inhibitors from Microbial Origin (1972) (6)
Characterization of tyrosine hydroxylase from bovine adrenal medulla. (1983) (6)
Parkinson’s Disease. From Clinical Aspects to Molecular Basis (1991) (6)
Hypothesis: neural mechanism of psychotherapy for the treatment of Parkinson’s disease: cognitive behavioral therapy (CBT), acceptance and commitment therapy (ACT), and Morita therapy? (2019) (6)
Activities of dipeptidyl peptidases in BXSB mice and MRL/lpr mice with lupus erythematosus-like syndrome. (1989) (6)
BIOSYNTHESIS OF C14-LABELLED FLAVIN ADENINE DINUCLEOTIDE BY EREMOTHECIUM ASHBYII. (1963) (5)
An Enzyme Immunoassay for Neopterin and Biopterin Using a Microtitre Plate Linked with N2-(3-Aminopropyl) Derivatives of Pteridines (1990) (5)
Atmospheric nuclear weapon test history as characterized by the deposition of 14C in human teeth. (1990) (5)
Tryptophan hydroxylase activity in brain slices. (1988) (5)
Assignment of A and B Types of Monoamine Oxidase in NCB20 Hybrid Cells to Those of the Parental Cells by Peptide Mapping (1986) (5)
Role of central 5-HT neurons upon predisposition to alcohol intake (1989) (5)
Inhibition of G protein-mediated differentiation of PC12 cells by an IMP dehydrogenase inhibitor, oxanosine (1994) (5)
Transfection of Tyrosine Hydroxylase cDNA into C6 Cells (1988) (5)
NEW INHIBITORS OF MICROBIAL ORIGIN FOR DOPAMINE-β-HYDROXYLASE (1973) (5)
In memory of Professor Leonor Michaelis in Nagoya: Great contributions to biochemistry in Japan in the first half of the 20th century (2013) (5)
Purification of dipeptidyl-aminopeptidase IV from human kidney by anti dipeptidyl-aminopeptidase IV affinity chromatography (1982) (5)
DOPA-responsive dystonia. From causative gene to molecular mechanism. (2001) (5)
Effects of deoxyspergualin on dipeptidyl peptidase-II and -IV in the spleen of BXSB mice and MRL/lpr mice during the development of the lupus erythematosus-like syndrome. (1992) (5)
[Structure and function of a novel ErbB ligand, NTAK]. (1998) (5)
Determination of phenylethanolamine N-methyltransferase activity in rat brain by high-performance liquid chromatography with fluorometric detection. (1982) (5)
A new assay of monoamine by gas chromatography (1983) (5)
Glycylprolyl beta-naphthylamidase activity in human serum. (1975) (5)
cAMP inhibits cytokine-induced biosynthesis of tetrahydrobiopterin in human umbilical vein endothelial cells. (2002) (5)
Microassay for GM1 ganglioside beta-galactosidase activity using high-performance liquid chromatography. (1988) (5)
Postnatal colocalization of tyrosine hydroxylase and choline acetyltransferase in neurons of the dorsal motor nucleus of the vagus of the laboratory shrew (Suncus murinus) (1997) (5)
CHAPTER 21 – BIOPTERIN COFACTOR AND MONOAMINE-SYNTHESIZING MONOOXYGENASES (1985) (5)
[Molecular mechanisms of neurotransmission]. (2000) (5)
Regulation of N-terminus-deleted human tyrosine hydroxylase type 1 by end products of catecholamine biosynthetic pathway (2005) (5)
IMMUNOHISTOCYTOCHEMICAL STUDIES ON NEURONS IN HAMSTER AREA POSTREMA (1983) (5)
Effects of Flavin Monosulphate and Flavin Adenine Dinucleotide on the Electroencephalogram (1958) (5)
Aripiprazole increases NAD(P)H–quinone oxidoreductase-1 and heme oxygenase-1 in PC12 cells (2015) (5)
Transient appearance of GTP cyclohydrolase I — positive non-monoaminergic neurons in the ventral lateral geniculate nucleus of postnatal mice (1996) (5)
Inhibition of tyrosine hydroxylase by naphthoquinone pigments of echinoids. (1972) (5)
A lysyl oxidase distinct from amine oxidase in bovine dental pulp. (1976) (5)
NT5DC2 affects the phosphorylation of tyrosine hydroxylase regulating its catalytic activity (2020) (5)
CONDENSATION REACTION OF DOPA WITH ETHYLENEDIAMINE (1960) (5)
Cloning and Sequencing of cDNA Encoding Human Sepiapterin Reductase (1991) (4)
Binding of specific glycoconjugates to human brain synaptosomes: studies using glycosylated β-galactosidase (1987) (4)
IMMUNOHISTOCYTOCHEMICAL AND BIOCHEMICAL STUDIES ON CATECHOLAMINE-SYNTHESIZING ENZYMES OF THE LUMBAR SYMPATHETIC GANGLIA AND SCIATIC NERVES OF BULLFROGS (1982) (4)
GTP cyclohydrolase I from Tetrahymena pyriformis: cloning of cDNA and expression. (2000) (4)
Acute effect of parathyroid hormone-(1-34) fragment on blood pressure in rats fed a low calcium diet. (1990) (4)
IMMUNOHISTOCHEMICAL LOCALIZATION OF CATECHOLAMINE-SYNTHESIZING ENZYMES AND SEROTONIN IN THE BAT BRAIN (1982) (4)
Effect of substance P C-terminal heptapeptide on amylase release in rat parotid gland. (1980) (4)
Effects of adrenergic drugs on the activity of tryptophan hydroxylase in midbrain raphe slices of the rat (1986) (4)
Involvement of β 1 -adrenergic receptors in regulation of the phosphorylation state of rat parotid gland proteins (1984) (4)
Dopamine β-hydroxylase in mammalian salivary glands (1974) (4)
[Huntington's disease model mouse and neuronal cell death]. (2001) (4)
Accumulation of N-methyl-4-phenylpyridinium ion (MPP+) in human melanoma cell line, HMV-I and -II (1988) (4)
AROMATIC L-AMINO ACID DECARBOXYLASE ACTIVITY IN BRAINS FROM NORMAL HUMAN SUBJECTS AND FROM PATIENTS WITH EXTRAPYRAMIDAL DISEASES (1981) (4)
Gas chromatographic determination of monoamine oxidase activity using mixed substrates. (1980) (4)
Intracellular Stability of Tyrosine Hydroxylase: Phosphorylation and Proteasomal Digestion of the Enzyme (2014) (4)
Transplacentally-transported 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) affects the catecholamine and indoleamine levels in the fetal mouse brain (1990) (4)
Condensation Product of Ethylenediamine with Noradrenaline or 3,4-Dihydroxymandelic Acid (1960) (4)
Subventricular Zone Under the Neuroinflammatory Stress and Parkinson’s Disease (2012) (4)
Enzymatic stimulation and enzymatic inhibition in Parkinson's disease (1993) (4)
A 24-hour rhythm in human serum dopamine-β-hydroxylase activity (1974) (4)
Changes in the activities of collagenase-like peptidase and dipeptidylaminopeptidase IV and hydroxyproline contents in developing rat salivary glands. (1980) (4)
Chapter 7 – Tyrosine Hydroxylase (2012) (4)
Dissociated release of tetrahydrobiopterin and nitric oxide by lipopolysaccharide from mouse neuroblastoma cells (1996) (4)
Presence of dipeptidyl peptidase II, dipeptidyl peptidase IV, and prolyl endopeptidase in effusion from patients with serous otitis media. (1990) (4)
Dopamine-beta-hydroxylase activity in stroke-prone spontaneously hypertensive rats. (1978) (4)
Distribution of beta 1- and beta 2-adrenoceptor subtypes in various mouse tissues. (1993) (4)
Elevation of blood pressure in young rats fed a low calcium diet. Effects of nifedipine and captopril. (1989) (4)
Lipopolysaccharide treatment arrests the cell cycle of BV-2 microglial cells in G1 phase and protects them from UV light-induced apoptosis (2014) (4)
Alterations in Catecholamine System Enzymes a (1995) (4)
Intracellular Localization of Monoamine Oxidase in Mammalian Salivary Glands (1971) (4)
Comparative measurements of urinary polyamines in early morning and 24-hour urine specimens. (1983) (4)
Effects of thyrotropin releasing hormone and its analogue, DN 1417, on biopterin concentration and tryptophan hydroxylation in rat raphe slices. (1987) (3)
Biochemical and Biological Studies on Dopastin, an Inhibitor of Dopamine β-Hydroxylase (1974) (3)
Comparison of characteristics of bovine aromatic L-amino acid decarboxylase with human enzyme. (1992) (3)
Two cell types in monoamine-containing ‘liquor contacting’ neuron system on the frog brain (1982) (3)
Cyclic AMP-dependent protein kinase activity in the human brain: values in Parkinsonism. (1979) (3)
Analysis of tetrahydroisoquinolines in the brain by gas chromatography/mass spectrometry (1993) (3)
Salsolinols and other 6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolines as inhibitors of monoamine oxidase: in vivo and in vitro study (1993) (3)
International Workshop Berlin Parkinson's Disease, January 30 - February 1, 1991 : how to proceed today in treatment : from basic research and early diagnosis to long-term treatment (1991) (3)
Changes in form of dipeptidyl-aminopeptidase IV in urine from patients with renal disease. (1981) (3)
Effect of Carbon Tetrachloride Administration on Serum Aromatic L-Amino Acid Decarboxylase Activity of the Rat (1986) (3)
Can tetrahydroisoquinoline (TIQ) or N-methyl-TIQ produce parkinsonism? (1991) (3)
Formation of Noradrenaline from Adrenaline by Rat Liver Mitochondria (1959) (3)
Dietary calcium deprivation increased the levels of plasma catecholamines and catecholamine-synthesizing enzymes of adrenal glands in rats. (1990) (3)
Presence of endogenous inhibitor of aromatic L-amino acid decarboxylase in monkey serum (1984) (3)
[Molecular genetics of hereditary progressive dystonia (HPD/Segawa's disease)]. (1996) (3)
The effect of methamphetamine on serotonin and its metabolite in the suprachiasmatic nucleus: A microdialysis study (2005) (3)
Developmental change of dopamine β-hydroxylase activity in cerebrospinal fluid of epileptic and non-epileptic children (2005) (3)
Quantitative immunofluorescence of tyrosine hydroxylase in the adrenal medulla of spontaneously hypertensive rats (1985) (3)
A microassay for acid β-galactosidase activity toward asialofetuin (1985) (3)
Purification and properties of human serum dopamine-β -hydroxylase (1977) (3)
Effects of polyamines on tyrosine hydroxylase activity in adrenals (1986) (3)
Serum Dopamine β-Hydroxylase Activity in Developing Spontaneously Hypertensive Rats and the Effect of Salt Administration (1975) (3)
The disappearance of serotonin by monoamine oxidase inhibitor insensitive agent in rat liver homogenate. (1965) (3)
Dopamine-β-Hydroxylase activity in serum of developing rats (1976) (3)
Catecholamines in the dental pulp. (1970) (3)
EFFECTS OF FLAVINS ON THE ELECTROENCEPHALOGRAM (1959) (3)
The effect of high phenylalanine concentration on the formation of DOPA from phenylalanine and tyrosine by tyrosine hydroxylase (1967) (3)
Effect of spermine on tyrosine hydroxylase activity before and after phosphorylation by cyclic AMP-dependent protein kinase. (1987) (3)
Inhibition of tyrosine hydroxylase, a Fe(II)-stimulated monooxygenase, by bleomycin. (1980) (3)
Multiple Forms of Glycylprolyl Dipeptidyl-Aminopeptidase in Serum and Tissues (1983) (3)
A new assay of monoamine oxidase by gas chromatography. (1983) (3)
A new assay of X-prolyl dipeptidyl-aminopeptidase activity in human serum with glycylproline p-phenylazoanilide as substrate (1979) (3)
Collagenase-like peptidase activity in serum from patients with rheumatoid arthritis (1985) (3)
Reduction of serum X-prolyl dipeptidyl-aminopeptidase activity in tumour-bearing mice and reversal of reduced enzyme activity by lentinan, an anti-tumour polysaccharide (1979) (3)
Inhibition of dopamine-beta-hydroxylase, A copper enzyme, by bleomycin. (1980) (3)
Tyrosine 3-monooxygenase from bovine adrenal medulla. (1987) (3)
A highly sensitive and specific FDCD method for chirality analysis of naturally occurring pteridines (2002) (3)
Identification of flavin in the purified beef brain mitochondrial monoamine oxidase (1969) (3)
Normal values for serum dopamine-beta-hydroxylase activity. (1977) (3)
Striatonigral degeneration combined with Alzheimer's disease (2004) (3)
Adrenal enzymes of catecholamine biosynthesis and metabolism in spontaneously hypertensive rats (1971) (3)
Dopamine-β-hydroxylase activity in stroke-prone spontaneously hypertensive rats (1978) (3)
Possible Mechanism for the Formation of Tumors by Thorotrast Based on Crystallographic Characterization of Thorotrast Particles in Tissues (1987) (2)
Stress-induced changes in in vivo and in vitro dopamine-beta-hydroxylase activity in spontaneously hypertensive rats. (1982) (2)
Induction of transient differentiation of rat pheochromocytoma PC12 cells by tyrosine kinase inhibitors (1992) (2)
Electrochemical Detection of Polyamines Using Immobilized Enzyme as Post-Column Reactor in High Performance Liquid Chromatography (1988) (2)
[Methodological considerations in microdialysis]. (1991) (2)
1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolines (Salsolinols) as inhibitors of tryptophan hydroxylase (1992) (2)
Correlation between serum dopamine-β-hydroxylase activity and dopamine-β-hydroxylase and tyrosine hydroxylase activities in central and peripheral adrenergic neurons and adrenal glands (1977) (2)
EFFECTS OF SUBSTANCE P RELATED PEPTIDES ON THE AMYLASE SECRETION IN RAT SALIVARY GLANDS (1981) (2)
Molecular genetics of DOPA-responsive dystonia. (1999) (2)
Specific Binding of Glycosylated β‐Galactosidase to Rat Clonal Pheochromocytoma PC12h Cells: Effects of Nerve Growth Factor and Gangliosides (1988) (2)
Identification of the Main Ethylenediamine Condensate of Noradrenaline with that of Catechol (1962) (2)
Biopterin in the Brain of Controls and Patients with Parkinson’s Disease and Related Striatal Degenerative Diseases: Application of New Biopterin Radioimmunoassay (1981) (2)
Changes of Quantity of Flavin in the Brain after Peripheral Administration of Flavins (1961) (2)
Noradrenaline-synthesizing enzymes in brain, serum, sympathetically innervated tissues, and adrenals of spontaneously hypertensive rats [proceedings]. (1977) (2)
Specific non-aminergic neuronal expression of human tyrosine hydroxylase in the brain of transgenic mice (1991) (2)
[Parkinson's disease--the molecular mechanism]. (1990) (2)
Neopterin and Cytokines in Hereditary Dystonia and Parkinson's Disease (1999) (2)
Roles of calcium in the regulation of tyrosine hydroxylase. (1989) (2)
Assay methods for polyamines (1993) (2)
A highly sensitive assay for non-specific N-methyltransferase activity in rat tissues by high-performance liquid chromatography with electrochemical detection. (1983) (2)
High-performance liquid chromatographic determination of diacetylpolyamines using benzoyl chloride as a derivatizing agent: Application to human urine (2001) (2)
Glycyl-prolyl-p-nitroanilidase (GPNAase) activity in cardiovascular diseases. (1979) (2)
[Monoamine oxidase inhibitors]. (1991) (2)
Genetic basis of dominant dystonia. (1998) (2)
Richard Kvetnansky: His Great Contributions to Research on Catecholamines and Other Neurotransmitters in Relation to Stress (2017) (2)
Subcellular distribution of tyrosine hydroxylase and monoamine oxidase in the bovine caudate nucleus (2005) (2)
Inhibition of human serum dopamineβ-hydroxylase after the oral administration of fusaric acid (1972) (2)
A radioassay for dopamine-beta-hydroxylase activity in rat serum. (1973) (2)
Application of In Vivo Voltammetry to Behavioral Pharmacology (1987) (2)
The cortical dopaminergic innervation as observed by immunohistochemistry using antiserum against dopamine in the rat brain (1987) (2)
Evidence for localization of the transgene product within axon terminals in the dentate gyrus of transgenic mice expressing human phenylethanolamine N-methyltransferase. A light and electron microscopic immunocytochemical study (1993) (2)
Inhibition of melanoma tyrosinase by fusaric acid (1972) (2)
Changes in dopamineβ-hydroxylase activity of monkey plasma with age (2005) (2)
Tetrahydroisoquinoline and its derivatives: the occurrence and the metabolism in the brain, and the effects on catecholamine metabolism (1991) (2)
Purification and properties of bovine brain dopamine beta-hydroxylase. (1982) (2)
Expression levels of Rab2, a G protein, and Bag-1, a Bcl-2 binding protein are controlled by withdrawal of nicotine from cultured pheochromocytoma PC12 cells (2005) (2)
Abnormality in Catecholamine Metabolism in the Brain of Spontaneously Hypertensive Rats (SHR) (1984) (2)
Presence of Protein Kinases in Dental Pulp and Phosphorylation of Intrinsic Proteins by These Enzymes In Vitro (1977) (2)
A simple assay for monoamine oxidase using glutathione peroxidase and glutathione reductase. (1984) (2)
Isolation of deoxybiopterin from urine of cancer patients (1995) (2)
Effect of Chronic Administration of 1,2,3,4-Tetrahydroisoquinoline and Its Derivatives on the Monkey: Immunohistochemical Study (1995) (2)
DETERMINATION OF BIOPTERIN AND NEOPTERIN IN FLUIDS AND TISSUES BY RADIOIMMUNOASSAY (1983) (2)
Dopamine β-Hydroxylase (1986) (2)
[Physiological and pathological chemistry of X-prolyl dipeptidyl-aminopeptidase (dipeptidyl-aminopeptidase IV)]. (1980) (2)
The effect of a heterocyclic amine, 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1), on tyrosine hydroxylase mRNA in PC12h cells (1993) (2)
Distribution of peptidases in cultured cells from middle ear mucosa: prolyl endopeptidase is localized in fibroblasts and dipeptidyl peptidase IV and II in epithelial cells. (1991) (2)
Genomic Organization of Mouse and Human GTP Cyclohydrolase I Genes and Mutations Found in the Human Gene (1995) (2)
Chemistry and Biological Function of Biopterin Cofactor and Related Compounds (1988) (2)
Effects of tyrosine administration on plasma biopterin in patients with juvenile parkinsonism and their relatives. (1987) (2)
6R-tetrahydrobiopterin biosynthesis: structures of rat and human sepiapterin reductase. (1992) (2)
Uptake of glycosylated β-galactosidase into human brain synaptosomes: Occurrence of two different systems for specific glycosides (1988) (1)
Quantification of tyrosine hydroxylase mRNA. (2001) (1)
The role of tyrosine hydroxylase as a key player in neuromelanin synthesis and the association of neuromelanin with Parkinson’s disease (2023) (1)
Immunocytochemical evidence of novel catecholamine- or biopterin-related neurons of mammalian brain. (1998) (1)
The phosphorylation of Ser40 of tyrosine hydroxylase has no effect on the stability of the enzyme in PC12 cells (2005) (1)
Gene Therapy of a Rodent Model of Parkinson’s Disease using Adeno-Associated Virus (AAV) Vectors (1998) (1)
[Management of radioactive wastes using a personal computer]. (1988) (1)
Molecular Biology of Catecholamine Systems: Multiple Tyrosine Hydroxylases in Different Simian Species, and in Humans in Relation to Parkinson’s Disease (1995) (1)
[Dopamine-beta-hydroxylase in serum--active and inactive forms of a serum enzyme (author's transl)]. (1974) (1)
Serotonin 5-HT2B receptor antagonism is fundamental for protecting PC12 cells exposed to hydrogen peroxide (2015) (1)
Corticotropin-releasing factor receptor antagonist attenuates LPS-induced increase of GTP cyclohydrolase I expression at murine locus coeruleus (2005) (1)
Dopamine-beta-hydroxylase activity in serum of developing rats. (1976) (1)
ISOTOPE EFFECTS IN THE HYDROXYLATION OF DOPAMINE BY DOPAMINE-ß-HYDROXYLASE (DBH) (1979) (1)
42. Immunohistocytochemical Localization of Amine-Containing Neurons Related to Circumventricular Organs of Vertebrates (1982) (1)
Hydrolysis of amino acid β-naphthylamides by aminopeptidases in the parotid gland (1970) (1)
Monoamine Oxidase Inhibitor (MAO-I)-Mediated Neuroprotection for Treating Parkinson’s Disease (2019) (1)
Evidence for localization of GTP cyclohydrolase I immunoreactivity in the mouse brain, adrenal gland and liver (1994) (1)
Analysis of an alternative promoter that regulates tissue-specific expression of the human aromatic L-amino acid decarboxylase gene in cultured cell lines (2005) (1)
Molecular genetic and metabolic aspects of hph-1,a mouse mutant deficient in gtp cyclohydrolase i activity (1996) (1)
Immunohistochemical and Biochemical Characterization of Phenylethanolamine-N-methyltransferase in the Bullfrog Sciatic Nerves, Sympathetic Ganglia and Adrenal Glands (1979) (1)
CHAPTER 25 – Elucidation of Regulatory Mechanism of Tyrosine Hydroxylase and Tryptophan Hydroxylase by Calmodulin Antagonists (1985) (1)
Ester-like groups in human dentine collagen. (1967) (1)
Salivary neopterin and related pterins: their comparison to those in plasma and changes in individuals. (2021) (1)
Histochemistry of MAO-A and MAO-B in the locus coeruleus of the Mongolian gerbil (2005) (1)
A fluorometric study of flavins in human saliva. (1967) (1)
Effect of oudenone on adrenal tyrosine hydroxylase activity in vivo and on tissue catecholamine concentrations. (1971) (1)
The effect of light exercise on the plasma superoxide dismutase activity and on the plasma noradrenaline concentration. (1981) (1)
An improved dual-wavelength spectrophotometric assay for dopamine-beta-hydroxylase. (1978) (1)
Folates and Pterins. Volume 2—Chemistry and Biochemistry of Pterins Edited by Raymond L. Blakley and Stephen J. Benkovic. ISBN No. 0471- 891-215. Price: £103.50. John Wiley, 1985 (1986) (1)
Tyrosine hydroxylase, tryptophan hydroxylase, biopterin, and neopterin in the brain of anorexia nervosa (2005) (1)
[Management of personnel exposure data with a personal computer]. (1988) (1)
Food-Derived Heterocyclic Amines as Potent Inhibitors of Catecholamine Metabolism (1990) (1)
[Molecular genetics of aromatic L-amino acid decarboxylase]. (1993) (1)
Effects of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) admimistration to the maternal mouse on the catecholamine system in the brain of postnatal mice (1991) (1)
Changes in dopamine beta-hydroxylase activity of monkey plasma with age. (1976) (1)
Phosphate and insoluble protein interaction in bovine dental pulp. (1975) (1)
[Polyamines and cancers (author's transl)]. (1981) (1)
Centrally mediated activation of tyrosine hydroxylation in rat adrenals by thyrotropin-releasing hormone. (1988) (1)
Serum collagenase-like peptidase activity in rheumatoid arthritis and systemic lupus erythematosus. (1985) (1)
Fluorescence assay of tyrosine hydroxylase activity in tissue homogenate (1968) (1)
Possible Coexistence of Taurine and Tyrosine Hydroxylase in the Periglomerular Cells of the Rat Olfactory Bulb (1985) (1)
Cognitive behavioral therapy (CBT), acceptance and commitment therapy (ACT), and Morita therapy (MT); comparison of three established psychotherapies and possible common neural mechanisms of psychotherapies (2021) (1)
Endogenous MPTP-Like Amines in the Brain: Isoquinolines (1994) (1)
[Abnormalities of catecholamine metabolism in spontaneously hypertensive rats (author's transl)]. (1981) (1)
Molecular biology of catecholamine neurons in relation to Parkinson's disease. (1996) (1)
Assay System for Neurotoxicants Causing Parkinson’s Disease: 1-Methyl-4-Phenylpyridinium Ion (MPP + ) Inhibits Survival of Cultured Neurons from Substantia Nigra of Fetal Monkey( Macaca fascicularis ) (1990) (1)
Proceedings: Excretion of cyclic AMP into duct saliva from the salivary gland. (1974) (1)
[Mechanism of induction of parkinsonism by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), a dopaminergic neurotoxin]. (1986) (1)
Tyrosine hydroxylase, tryptophan hydroxylase, biopterin and neopterin in the brains and biopterin and neopterin in sera from patients with Alzheimer’s disease (1990) (1)
Dopamine-β-hydroxylase activity in human peripheral tissues: Comparison between sudden death and chronic illness (1980) (1)
A new Fluoroimmunoassay of Biopterin and Neopterin in Human Urine (1985) (1)
Distribution of Activities of Collagen-Related Peptidases in Human Tissues (1984) (1)
Catecholamine synthetic enzymes of spontaneously hypertensive rats and microbial hypotensive products (1973) (1)
[Pathogenic substances in Parkinson disease and new therapeutics considering the etiologic mechanism]. (1988) (1)
[Biochemistry of biogenic amines--recent advances]. (1983) (1)
Parkinson's disease: degenerative brain disease: a molecular biology approach (1989) (1)
408 Changes in monoamine levels in mouse brain elicited by forced-swimming stress, and the effect of RS-8359, a monoamine oxidase inhibitor (1993) (1)
Protein products of the bacterial reporter gene are found within axon terminals in the brain of transgenic mice (1994) (1)
Serum dopamine-β-hydroxylase in spontaneously hypertensive rats (1972) (1)
2410 An animal model for autonomic neuropathy in transgenic mice (1997) (0)
Amino acid composition of insoluble protein from the dentine of human deciduous and permanent teeth. (1971) (0)
[Peroxidase activity of the saliva. 3. Activities of the salivary glands]. (1967) (0)
Uptake of L-threo-dihydroxyphenylserine into human brain synaptosomes (2005) (0)
Inhibitory Effects of Endogenous Tetrahydroisoquinolines on Mitochondrial Respiration in Mouse Brain (1995) (0)
SimultaneousFluorometryof UrinaryDopamine , Norepinephrine , and EpinephrineComparedwith LiquidChromatographywith Electrochemical Detection (2004) (0)
Immunohistochemical localization of tyrosine hydroxylase, aromatic-L-aminoacid decarboxylase, phenylethanolamine-N-methyltransferase and serotonin in monoaminergic neurons of the suncus brain (1989) (0)
G-proteins(Go,Gi) in the striatum in Parkinson's disease (1994) (0)
Application of HPLC for analysis and purification of catecholamine-synthesizing enzymes (2020) (0)
[Tyrosine hydroxylase (author's transl)]. (1976) (0)
Neuroprotective or neurotoxic phenotypes of activated microglia in neonatal mice in neuronal injuries (2009) (0)
Cyclosporin a Enhances Neurotoxicity of N-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) in Mice (1990) (0)
STUDIES ON BIOLOGICALLY ACTIVE PTERIDINES. IV. SYNTHESIS OF SEVERAL BIOPTERIN N DERIVATIVES AS AN ANTIGEN IN RADIOIMMUNOASSAY FOR BIOPTERIN (1980) (0)
Elevations of blood pressure and plasma catecholamines in rat with hyperparathyroidism (1988) (0)
Tribute to Professor Hideya Saito (2002) (0)
High-performance liquid chromatography for enkephalins and enkephalin-containing peptides (2020) (0)
714 Transgenic analysis of tyrosine hydroxylase promoter using different reporter genes (1993) (0)
Correlation between serum dopamine-beta-hydroxylase activity and dopamine-beta-hydroxylase and tyrosine hydroxylase activities in central and peripheral adrenergic neurons and adrenal glands. (1977) (0)
Structure and function of NTAK, a novel ligand of receptor tyrosine kinase ErbB (2000) (0)
Changes in Urinary Activity of Dipeptidyl-Aminopeptidase IV:X-Prolyl Dipeptidyl-Aminopeptidase in Renal Diseases (1979) (0)
[Molecular biology of hereditary dystonia]. (1998) (0)
GTP cyclohydrolase I activities in mononuclear blood cells in patients with dopa-responsive dystonia and normal individuals (1998) (0)
Calcium ion as a second messenger in the regulation of tyrosine hydroxylase activity (1989) (0)
Remembering Keisuke Fujita, M.D., Ph.D., President and Founder of Fujita Health University, and his contributions to medical science and education (2021) (0)
Pharmacotherapy for Cocaine Use Disorders (2021) (0)
Effect of N-methylisoquinolinium ion (NMIQ+) on catecholamine metabolism (1989) (0)
Neuroscience 2009 Committee (2009) (0)
Biosynthesis of N-Methylisoquinolinium Ion, a Potent Inhibitor of Catecholamine Metabolism, from 1,2,3,4-Tetrahydroisoquinoline Through N-Methyl-1,2,3,4-Tetrahydroisoquinoline in Human Brain (1990) (0)
804 Gene structures of three tetrahydrobiopterin-synthesizing enzymes and the regulatory mechanisms of their expression 1 (1997) (0)
Immunoflxation : Application to the IdentificatIonof “ DIffIcult ” MonocionaiComponents (2004) (0)
The circadian variation of the serum dopamine-β-hydroxylase activity as a biochemical marker in schizophrenia (1992) (0)
Marshall Warren Nirenberg, Honorary member of JSN: Nobel Laureate and Giant of Science (2012) (0)
[Parkinson's disease]. (1984) (0)
[Secretion of injected vitamin B2 into the saliva]. (1966) (0)
Cotransduction of tyrosine hydroxylase and aromatic L-amino acid decarboxylase genes into cultured striatal cells using adeno-associated virus vectors. (1998) (0)
Acknowledgment to reviewers (1979) (0)
Ultrastructural study on human tyrosine hydroxylase expression in the olfactory system of transgenic mice (1991) (0)
[V-1, a catecholamine biosynthesis regulatory protein, enhances GTP cyclohydrolase I gene transcription in a cAMP-responsive element dependent manner]. (2002) (0)
The mechanisms underlying the therapeutic action, the adverse side-effects, and the decline in efficacy upon prolonged administration of L-DOPA in patients with Parkinson's disease (2011) (0)
Marshall Nirenberg (1927–2010) – Nobel Laureate, Giant of Neurochemistry and Molecular Biology, and Honorary Member of Japan Society for Neurochemistry (2010) (0)
Purification and properties of an amine oxidase in bovine dental pulp (1971) (0)
Immunocytochemical study of human dopamine-β-hydroxylase gene expression in the brain of transgenic mice (1992) (0)
A Study on Axoplasmic Transport of Tyrosine Hydroxylase by Immunofluorescent and Biochemical Methods (1977) (0)
Expression of the human tyrosine hydroxylase gene in transgenic mice (1992) (0)
719 Transgene product is found within axon terminals in the brain of transgenic mice (1993) (0)
Monoamine oxidase activity of the thyroid glands in thyroid disease. (1969) (0)
Cytokines and Neurotrophins in Parkinson’s Disease: Involvement in Apoptosis (2002) (0)
THE PRIMARY STRUCTURE OF SEPIAPTERIN REDUCTASE.(Biochemistry)(Proceedings of the Sixty-Second Annual Meeting of the Zoological Society of Japan) (1991) (0)
20. NeurochemistryIsolation of a full-length cDNA clone encoding human phenylethanolamine N-methyltransferase (1988) (0)
Tyrosine hydroxylase in relation to Parkinson’s disease: a historical overview and future prospect (1991) (0)
Selective toxicity of 1-methyl-4-phenylpyridinium ion (MPP+) to pigmented melanoma cells in vitro. (1991) (0)
Tissue specific regulation of the human tyrosine hydroxylase expression in transgenic mice (1992) (0)
[Autosomal-dominant DOPA-responsive dystonia, caused by mutations in the GTP-cyclohydrolase I gene]. (1998) (0)
[Methods of monoamine determination]. (1978) (0)
Transplacental uptake of N-methyl-4-phenyl-1,2,3,6,-tetrahydropyridine (MPTP) from mother mouse into fetal brains (1989) (0)
[Tyrosine hydroxylase, a specific enzyme involved in the biosynthesis of catecholamines in the brain and sympathetically innervated tissues]. (1965) (0)
Simple and sensitive assay of dopamine beta-hydroxylase in human cerebrospinal fluid by high-performance liquid chromatography with electrochemical detection. (1985) (0)
Serum aromatic L-amino acid decarboxylase activity in patients with acute hepatitis. (1987) (0)
The inhibitory effect of serotonin autoreceptor stimulation on the activity of tryptophan hydroxylase in rat raphe slices (1985) (0)
Application of microdialysis to the central nervous system (1989) (0)
A microassay for acid beta-galactosidase activity toward asialofetuin. (1985) (0)
Review of: "Gene therapy in the putamen for curing AADC deficiency and Parkinson's disease" (2021) (0)
Analysis of enzymes in catecholamine biosynthesis (1993) (0)
Myocardial ischemia stimulates catecholamine synthesis and catabolism in the dog adrenal medulla. (1986) (0)
A SENSITIVE ASSAY FOR NON-SPECIFIC N-METHYLTRANSFERASE ACTIVITY IN RAT TISSUES BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY ELECTROCHEMICAL DETECTION (2017) (0)
Subventricular Zone Under the Neuroinflammatory Stress and Parkinson’s Disease (2011) (0)
Mice lacking the tyrosine hydroxylase gene and transcomplementation with the human genome : ongoing prospects for human gene therapy (1999) (0)
Identification and Characterization of a Novel Phorbol Ester-responsive DNA Sequence in the 5 *-Flanking Region of the Human Dopamine b-Hydroxylase Gene * (1998) (0)
Increased sympathetic function in transgenic mice overexpressing V-1, a novel catecholamine biosynthesis-promoting factor (2001) (0)
Application of In VIVO Voltammeby to Behavioral Pharmacology (1987) (0)
43. Immunohistochemical Study on Monoaminergic Neuron Systems in Frog Brain (1982) (0)
39-115 The changes of plasma biopterin levels in the depressives and the fluctuation of plasma biopterin levels for a day (1997) (0)
[Brain aging and Parkinson's disease]. (1990) (0)
1218 Survival of tyrosine hydroxylase-positive cells and behavioral recovery after introduction of TH gene using adenoviral vector (1997) (0)
Dopamine-beta-hydroxylase activity in human peripheral tissues: comparison between sudden death and chronic illness. (1980) (0)
Molecular Genetic Analysis of Plasma Dopamine β-Hydroxylase in Depression (2002) (0)
Richard Kvetnansky: His Great Contributions to Research on Catecholamines and Other Neurotransmitters in Relation to Stress (2017) (0)
A new immunoassay for neopterin and biopterin (1990) (0)
Gene Therapy for Parkinson’s Disease Using Aav Vectors (2002) (0)
Human tyrosine hydroxylase expression in midbrain neurons of transgenic mice by in situ hybridization (1991) (0)
PhotometricAssayof Dopamine-3-Hydroxylase (2004) (0)
[Genetic conversion of neurotransmitter phenotype in transgenic mice]. (1993) (0)
Down-regulation of 14-3-3η protein by RNAi increases stability of exogenous tyrosine hydroxylase in PC12D cells (2008) (0)
GC/MS study on metabolism of tetrahydroisoquinoline, an endogenous MPTP-like substance, in brain (1989) (0)
Tyrosine hydroxylase - Molecular genetic approaches. (1989) (0)
Management of radioactive wastes by personal computer. (1988) (0)
[Genes for human catecholamine-synthesizing enzymes: the structure, expression, and pathology]. (1992) (0)
[Dopamine beta-hydrolase]. (1983) (0)
[Peroxidase activity of the saliva. 1. Origin of the activity]. (1966) (0)
[The search for endogenous or exogenous MPTP-like substances]. (1989) (0)
In Memory of Dr. Sidney Udenfriend (2002) (0)
STUDIES ON BIOLOGICALLY ACTIVE PTERIDINES. II. SYNTHESIS OF SOME 2-PYRIMIDINYL- AND 2-PTERIDINYLAMINO ACIDS (1980) (0)
Immunotoxin-mediated conditional disruption of specffic neurons in transgenic mice ( recombinant immunotoxin / dopamine P-hydroxylase / interleukin 2 receptor / cell ablation ) (2005) (0)
[Schizophrenia and neurotransmitters]. (1984) (0)
3002 Gene transfer specific for brain using microglial cell lines (1997) (0)
Peripherally injected lipopolysaccharide induces apoptosis in the subventricular zone and rostral migration stream of adult mice (2010) (0)
Activities of peptidases in the brain from parkinsonian patients (1991) (0)
187. Existence of Dopamine Cells and Serotonin Cells in Frog Pituitary Gland (1982) (0)
Estimation of Biopterin and Neopterin in Cerebrospinal Fluid in Parkinson’s Disease (1990) (0)
[Microdialysis: a method to construct a microdialysis probe and its applications]. (1990) (0)
Changes in mRNA contents of aromatic L-amino acid decarboxylase and tyrosine hydroxylase isoenzymes (hTH1 ∼ hTH4) in the substantia nigra from control, parkinsonian, and schizophrenic patients (1994) (0)
The phosphorylation of Ser40 of tyrosine hydroxylase has no effect on the intracellular stability of the enzyme (2006) (0)
Analysis of motor, learning, and pituitary function in dopamine-deficient mice (1998) (0)
Purification and properties of human serum dopamine-beta-hydroxylase. (1977) (0)
Molecular Basis of DOPA-Responsive Dystonia (2002) (0)
Emotional behavior and endocrine function in dopamine-deficient mutant mice (1998) (0)
Transgenic Strategies in Autonomic Research (2004) (0)
Advances in neurochemistry, vol. 4 Edited by B. W. Agranoff and M. H. Aprison. Published by Plenum Press, New York, 1982 (1983) (0)
[Identification of the causative gene for Segawa's disease]. (2007) (0)
Retrograde axoplasmic transport to inactive dopamine beta-hydroxylase in sciatic nerves. (1976) (0)
Correction to: Hypothesis: neural mechanism of psychotherapy for the treatment of Parkinson’s disease: cognitive behavioral therapy (CBT), acceptance and commitment therapy (ACT), and Morita therapy? (2020) (0)
Studies on Biologically Active Pteridines. VI. Biopterin Conjugated to β-D-Galactosidase and Bovine Serum Albumine (1981) (0)
INHIBITION OF TETRAHYDROBIOPTERIN SYNTHESIS BY PHENYLPYRIDINE DERIVATIVES : Biochemistry (1986) (0)
[Biological dynamics and metabolism of polyamines]. (1984) (0)
Inhibition of human brain monoamine oxidase by heterocyclic amines (1989) (0)
Origin ofCyclic Adenosine Monophosphate inSaliva (1974) (0)
Dopamine beta-hydroxylase in mammalian salivary glands. (1974) (0)
Immunohistocytochemistry of Tetrahydrobiopterin (1983) (0)
Peter Riederer, a translational neurobiochemist (2022) (0)
Co-Induction of Tetrahydrobiopterin and Catecholamine Syntheses in V-l-OVerexpressing PC12D Cells (2002) (0)
Delayed reduction of the protein level in the striatum after genetic ablation of the tyrosine hydroxylase gene in the substantia nigra (2007) (0)
Subject Index Vol. 17, 1987 (1987) (0)
522 – CYCLIC AMP IN SALIVARY GLAND AND SALIVA (1977) (0)
[Abnormalities of catecholamine metabolism in Parkinson's disease (author's transl)]. (1981) (0)
Serum collagenase-like peptidase activity correlated with bone mineral density. A study of 102 elderly women. (1993) (0)
Enhancement of Noradrenergic Phenotype Expression in Transgenic Mice Overexpressing V-1, A Cytoplasmic Ankyrin Repeat Protein (2002) (0)
Metabolism of Neurogenic Monoamines (1978) (0)
Role of Microglia in Inflammatory Process in Parkinson’s Disease (2011) (0)
Continuous measurement in a greenhouse reveals high COP of air-source heat pump in winter (2015) (0)
Molecular Genetics of Catecholamines: Key Molecules Bridging Basic Science with Clinical Science (2002) (0)
[Parkinsonism and MPTP (methylphenyltetrahydropyridine)]. (1986) (0)
Progress in HPLC ECD method. (1990) (0)
A systematic review on aromatic L-amino acid decarboxylase (5-hydroxytryptophan decarboxylase) (1988) (0)
Quantification of m R N A of tyrosine hydroxylase and aromatic L-amino acid decarboxylase in the substantia nigra in Parkinson ' s disease and schizophrenia Rapid Communication (0)
Dihydroxytetrahydroisoquinolines induced monoamine release; in vivo microdialysis study (1992) (0)
Lewy bodies, iron, inflammation and neuromelanin: pathological aspects underlying Parkinson’s disease (2023) (0)
Dopamine-beta-hydroxylase activity in human cerebrospinal fluid and serum. (1977) (0)
General assay methods of biogenic amines (1975) (0)
Detection and quantitation of tyrosine hydroxylase mRNAs in the human brain (1992) (0)
Expression levels of Egr-1 and Nur77 proteins in mouse brain are increased by withdrawal of nicotine (2007) (0)
Immobilized phenylalanine hydroxylase through the SH groups. (1986) (0)
A new assay of monoamine oxidase activity for selective substrates and inhibitors. (1983) (0)
Analysis of neuropeptides by high-performance liquid chromatography (1993) (0)
1731 Transient appearance of gtp cyclohydrolase i-positive non-monoaminergic neurons in the ventral lateral geniculate nucleus of the postnatal mice (1996) (0)
Microglia Activation and Gene Expression of Cytokines in Parkinson’s Disease (2008) (0)
The effects of subchronic TRH and DN 1417 on tryptophan hydroxylation in rat raphe slices; role of biopterin in serotonin biosynthesis (1986) (0)
New dipeptide derivatives and their salts, as well as methods for measurement of enzymaktivitaet using these dipeptide derivatives (1976) (0)
A Specific Antiserum Against Tetrahydrobiopterin: Its Preparation and Application to Immunohistochemistry (1983) (0)
Inducible ablation of specific neuron types in the central nervous system of transgenic mice (1994) (0)
713 Increased heterogeneity of tyrosine hydroxylase in humans (1993) (0)
Immunocytochemical study on human tyrosine hydroxylase expression in sensory neurons of transgenic mice (1991) (0)
Detection of Tetrahydroisoquinoline, a Parkinsonism-Related Compound, in Parkinsonian Brains and Foods by Gas Chromatography-Mass Spectrometry (1990) (0)
Human Specific Antibody Raised against Oligopeptides of Human Dopamine-B-hydroxylase. (1990) (0)
Parkinsoism Produced by an Endogenous Substance, Tetrahydroisoquinoline, in Monkeys and Mice (1990) (0)
Biopterin metabolism in patients with malignant syndrome. (2003) (0)
Interaction of catecholamines and indoleamines in the brain (1992) (0)
Ascorbate 2-sulfate inhibits dopamine beta-hydroxylase reaction, but not ascorbate oxidase reaction. (1975) (0)
Dopamine Neurons are Not Affected by Expanded Polyglutamine Stretches in HD Gene Knock-In Mice (2002) (0)
Crystalline picrate of the condensation product of ethylenediamine with noradrenaline or with catechol. (1962) (0)
CATECHOLAMINE SYNTHESIZING ENZYMES IN HYPERTENSION (1976) (0)
Proceedings: Serum dopamine beta-hydroxylase activity in developing spontaneously hypertensive rats and the effect of salt administration. (1975) (0)
The presence of immunoreactivities to all four catecholamine synthesizing enzymes and tetrahydrobiopterin in Tetrahymena pyriformis (1987) (0)
Identification of the Main Ethylene-diamine Condensate of Noradrenaline with that of Catechol (1962) (0)
Molecular aspects of the dopaminergic neurotoxins in relation to tyrosine hydroxylase isoforms (1996) (0)
[Peroxidase activity of the saliva. 2. Its relation to oral diseases]. (1967) (0)
Overexpression of V‐1 prevents nitric oxide‐induced cell death: Involvement of enhanced tetrahydrobiopterin biosynthesis (2003) (0)
NEW APPROACHES TO THE TREATMENT OF PARKINSON'S DISEASE IN JAPAN: (1984) (0)
[Induction of the enzymes related to neurogenic amines (author's transl)]. (1977) (0)
[Amines and pteridines]. (1996) (0)
[The relation between metabolism of biopterin and dystonia-parkinsonism]. (1999) (0)
EUaited States Patent ( 19 ) (2017) (0)
Determination of Tetrahydropterins as Native Pteridines in Two Microorganisms, Tetrahymena Pyriformis and E. Coli (2002) (0)
Inhibition of dopamine beta-hydroxylase by aquayamycin. (1968) (0)
Incorporation of glycosylated beta-galactosidase into bovine brain synaptosomes. (1986) (0)
[Polarization fluoroimmunoassay of biopterin and neopterin]. (1987) (0)
15 Role of Microglia in Inflammatory Process in Parkinson ’ s Disease (2012) (0)
Distribution of GTP Cyclohydrolase-I, Neopterin, and Biopterin in the Human Brain (1986) (0)
CHARACTERIZATION OF RAT AND HUMAN SEPIAPTERIN REDUCTASE GENES(Biochemistry)Proceedings of the Sixty-Third Annual Meeting of the Zoologiacal Socistry of Japan (1992) (0)
Application of FDCD Spectroscopy for Determination of Chiralities of Biologically Important Pteridines (2002) (0)

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Toshiharu (toshi) Nagatsu is affiliated with the following schools:

Fujita Health University

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What Schools Are Affiliated With Toshiharu (toshi) Nagatsu?

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