Toshikazu Ushijima
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Computer Science
Toshikazu Ushijima's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science University of Tokyo
- Bachelors Computer Science University of Tokyo
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(Suggest an Edit or Addition)Toshikazu Ushijima's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Causal Relationship between the Loss of RUNX3 Expression and Gastric Cancer (2002) (1064)
- High Levels of Aberrant DNA Methylation in Helicobacter pylori–Infected Gastric Mucosae and its Possible Association with Gastric Cancer Risk (2006) (610)
- Detection and interpretation of altered methylation patterns in cancer cells (2005) (481)
- The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery (2016) (360)
- Inflammatory processes triggered by Helicobacter pylori infection cause aberrant DNA methylation in gastric epithelial cells. (2010) (352)
- Inflammation-associated cancer development in digestive organs: mechanisms and roles for genetic and epigenetic modulation. (2012) (335)
- Focus on gastric cancer. (2004) (303)
- DNA methylation of microRNA genes in gastric mucosae of gastric cancer patients: Its possible involvement in the formation of epigenetic field defect (2009) (254)
- Chemical genomic screening for methylation‐silenced genes in gastric cancer cell lines using 5‐aza‐2′‐deoxycytidine treatment and oligonucleotide microarray (2006) (253)
- Epigenetic mechanisms of chronic pain (2015) (247)
- Epigenetic field for cancerization. (2007) (235)
- CpG island methylator phenotype is a strong determinant of poor prognosis in neuroblastomas. (2005) (209)
- Moving AHEAD with an international human epigenome project (2008) (202)
- Establishment of methylation-sensitive-representational difference analysis and isolation of hypo- and hypermethylated genomic fragments in mouse liver tumors. (1997) (200)
- A specific CpG site demethylation in the human interleukin 2 gene promoter is an epigenetic memory (2006) (191)
- Identification of silencing of nine genes in human gastric cancers. (2002) (189)
- Aberrant methylations in cancer cells: Where do they come from? (2005) (188)
- Hippocampal epigenetic modification at the brain‐derived neurotrophic factor gene induced by an enriched environment (2011) (181)
- RUNX3 Suppresses Gastric Epithelial Cell Growth by Inducing p21WAF1/Cip1 Expression in Cooperation with Transforming Growth Factor β-Activated SMAD (2005) (181)
- Silencing of Peroxiredoxin 2 and aberrant methylation of 33 CpG islands in putative promoter regions in human malignant melanomas. (2006) (173)
- Lysyl Oxidase Is a Tumor Suppressor Gene Inactivated by Methylation and Loss of Heterozygosity in Human Gastric Cancers (2004) (171)
- Fidelity of the methylation pattern and its variation in the genome. (2003) (171)
- Identification of 20 genes aberrantly methylated in human breast cancers (2005) (151)
- Diagnostic and therapeutic applications of epigenetics. (2005) (150)
- DNA methylation as a marker for the past and future (2006) (147)
- Hereditary diffuse gastric cancer: updated clinical practice guidelines. (2020) (145)
- Cancer development based on chronic active gastritis and resulting gastric atrophy as assessed by serum levels of pepsinogen and Helicobacter pylori antibody titer (2014) (143)
- Down-regulation of a gastric transcription factor, Sox2, and ectopic expression of intestinal homeobox genes, Cdx1 and Cdx2: inverse correlation during progression from gastric/intestinal-mixed to complete intestinal metaplasia (2004) (142)
- Specific 5'-GGGA-3'-->5'-GGA-3' mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. (1995) (141)
- Methylation-associated silencing of heparan sulfate D-glucosaminyl 3-O-sulfotransferase-2 (3-OST-2) in human breast, colon, lung and pancreatic cancers (2003) (137)
- Recurrent mutations of CD79B and MYD88 are the hallmark of primary central nervous system lymphomas (2016) (137)
- Genome-wide profiling of promoter methylation in human (2006) (136)
- The presence of aberrant DNA methylation in noncancerous esophageal mucosae in association with smoking history (2009) (133)
- The presence of RNA polymerase II, active or stalled, predicts epigenetic fate of promoter CpG islands. (2009) (131)
- Attractin/mahogany/zitter plays a critical role in myelination of the central nervous system. (2001) (129)
- Detection of retTPC/PTC transcripts in thyroid adenomas and adenomatous goiter by an RT-PCR method. (1991) (127)
- Identification of 27 5′ CpG islands aberrantly methylated and 13 genes silenced in human pancreatic cancers (2004) (124)
- Higher Methylation Levels in Gastric Mucosae Significantly Correlate with Higher Risk of Gastric Cancers (2006) (123)
- Accumulation of genetic and epigenetic alterations in normal cells and cancer risk (2019) (122)
- Frequent hypomethylation in multiple promoter CpG islands is associated with global hypomethylation, but not with frequent promoter hypermethylation (2004) (122)
- Aberrant DNA methylation in contrast with mutations (2010) (119)
- Epigenetic transcriptional activation of monocyte chemotactic protein 3 contributes to long-lasting neuropathic pain. (2013) (117)
- How to stomach an epigenetic insult: the gastric cancer epigenome (2017) (115)
- The presence of a methylation fingerprint of Helicobacter pylori infection in human gastric mucosae (2009) (115)
- Demonstration of the usefulness of epigenetic cancer risk prediction by a multicentre prospective cohort study (2014) (114)
- Epigenetic regulation of autophagy by the methyltransferase EZH2 through an MTOR-dependent pathway (2015) (114)
- Sox2 expression in human stomach adenocarcinomas with gastric and gastric‐and‐intestinal‐mixed phenotypes (2005) (112)
- Hypomethylation of LINE1 retrotransposon in human hepatocellular carcinomas, but not in surrounding liver cirrhosis. (2000) (110)
- Inflammation-induced repression of tumor suppressor miR-7 in gastric tumor cells (2012) (108)
- Persistence of a component of DNA methylation in gastric mucosae after Helicobacter pylori eradication (2009) (107)
- Molecular Pathways: Involvement of Helicobacter pylori–Triggered Inflammation in the Formation of an Epigenetic Field Defect, and Its Usefulness as Cancer Risk and Exposure Markers (2011) (106)
- Enhanced IL‐1β production in response to the activation of hippocampal glial cells impairs neurogenesis in aged mice (2010) (105)
- Promoter methylation profiling of 30 genes in human malignant melanoma (2004) (104)
- cDNA cloning and characterization of ret activated in a human papillary thyroid carcinoma cell line. (1990) (103)
- Integrated analysis of cancer-related pathways affected by genetic and epigenetic alterations in gastric cancer (2014) (101)
- Acquired loss of p53 induces blastic transformation in p210(bcr/abl)-expressing hematopoietic cells: a transgenic study for blast crisis of human CML. (2000) (98)
- Silencing of the UCHL1 gene in human colorectal and ovarian cancers (2006) (97)
- Frequent PTPRK–RSPO3 fusions and RNF43 mutations in colorectal traditional serrated adenoma (2016) (96)
- Development of gastric cancer in nonatrophic stomach with highly active inflammation identified by serum levels of pepsinogen and Helicobacter pylori antibody together with endoscopic rugal hyperplastic gastritis (2012) (95)
- Genetic changes induced by heterocyclic amines. (1997) (94)
- Methylation‐associated silencing of the Wnt antagonist SFRP1 gene in human ovarian cancers (2004) (93)
- Epigenetic impact of infection on carcinogenesis: mechanisms and applications (2016) (87)
- Germline mutation of BRCA1 in Japanese breast cancer families. (1995) (85)
- Genetic and epigenetic alterations in carcinogenesis. (2000) (80)
- Role of transcriptional and posttranscriptional regulation of methionine adenosyltransferases in liver cancer progression (2012) (79)
- Incidence of and risk factors for metachronous gastric cancer after endoscopic resection and successful Helicobacter pylori eradication: results of a large-scale, multicenter cohort study in Japan (2016) (78)
- Decreased expression of the seven ARP2/3 complex genes in human gastric cancers. (2004) (78)
- Insufficient role of cell proliferation in aberrant DNA methylation induction and involvement of specific types of inflammation. (2011) (78)
- Mechanisms for the induction of gastric cancer by Helicobacter pylori infection: aberrant DNA methylation pathway (2017) (78)
- Early-stage formation of an epigenetic field defect in a mouse colitis model, and non-essential roles of T- and B-cells in DNA methylation induction (2012) (77)
- Involvement of RET oncogene in human tumours: specificity of RET activation to thyroid tumours. (1993) (75)
- Large-Scale Characterization of DNA Methylation Changes in Human Gastric Carcinomas with and without Metastasis (2014) (75)
- Dietary carcinogens and mammary carcinogenesis. Induction of rat mammary carcinomas by administration of heterocyclin amines in cooked foods (1994) (74)
- Identification of coexistence of DNA methylation and H3K27me3 specifically in cancer cells as a promising target for epigenetic therapy. (2015) (66)
- Applying whole-genome studies of epigenetic regulation to study human disease (2006) (66)
- Interleukin-1β induced by Helicobacter pylori infection enhances mouse gastric carcinogenesis. (2013) (66)
- Agreement of mutational characteristics of heterocyclic amines in lacI of the Big Blue mouse with those in tumor related genes in rodents. (1997) (65)
- Reduced Expression of GNA11 and Silencing of MCT1 in Human Breast Cancers (2003) (65)
- Dose-dependent roles for canonical Wnt signalling in de novo crypt formation and cell cycle properties of the colonic epithelium (2013) (63)
- Prevention of Helicobacter pylori–Induced Gastric Cancers in Gerbils by a DNA Demethylating Agent (2013) (62)
- Neuron-specific methylome analysis reveals epigenetic regulation and tau-related dysfunction of BRCA1 in Alzheimer’s disease (2017) (62)
- Alu and Satα hypomethylation in Helicobacter pylori‐infected gastric mucosae (2011) (62)
- Comprehensive analyses using next-generation sequencing and immunohistochemistry enable precise treatment in advanced gastric cancer. (2016) (60)
- Significance of molecular classification of ependymomas: C11orf95-RELA fusion-negative supratentorial ependymomas are a heterogeneous group of tumors (2018) (60)
- Genome-wide methylation profiles in primary intracranial germ cell tumors indicate a primordial germ cell origin for germinomas (2017) (59)
- Preferential induction of guanine deletion at 5'-GGGA-3' in rat mammary glands by 2-amino- 1-methyl-6-phenylimidazo[4,5-b]pyridine. (1999) (59)
- ANGPTL4 is a secreted tumor suppressor that inhibits angiogenesis (2014) (59)
- Overexpression of PIK3CA is associated with lymph node metastasis in esophageal squamous cell carcinoma. (2009) (58)
- Genetic and epigenetic alterations in normal tissues have differential impacts on cancer risk among tissues (2018) (58)
- Comprehensive DNA methylation and extensive mutation analyses reveal an association between the CpG island methylator phenotype and oncogenic mutations in gastric cancers. (2013) (58)
- Revisit of Field Cancerization in Squamous Cell Carcinoma of Upper Aerodigestive Tract: Better Risk Assessment with Epigenetic Markers (2011) (58)
- Compendium of aberrant DNA methylation and histone modifications in cancer. (2014) (57)
- Lack of association between CpG island methylator phenotype in human gastric cancers and methylation in their background non‐cancerous gastric mucosae (2007) (56)
- No-observed effect levels for carcinogenicity and for in vivo mutagenicity of a genotoxic carcinogen. (2004) (56)
- Roadmap for Investigating Epigenome Deregulation and Environmental Origins of Cancer (2017) (56)
- Organ variation in the mutagenicity of MeIQ in Big Blue lacI transgenic mice. (1996) (56)
- Methylation‐Sensitive Representational Difference Analysis and Its Application to Cancer Research (2003) (56)
- Instability of microsatellites in rat colon tumors induced by heterocyclic amines. (1994) (54)
- Genetic alterations of androgen receptor gene in Japanese human prostate cancer. (1997) (54)
- Recurrent neomorphic mutations of MTOR in central nervous system and testicular germ cell tumors may be targeted for therapy (2016) (54)
- Identification of a TLR2-regulated gene signature associated with tumor cell growth in gastric cancer (2017) (53)
- Autophagy impairment by Helicobacter pylori‐induced methylation silencing of MAP1LC3Av1 promotes gastric carcinogenesis (2017) (52)
- Silencing of HTR1B and reduced expression of EDN1 in human lung cancers, revealed by methylation-sensitive representational difference analysis (2001) (52)
- Induction of epigenetic alterations by chronic inflammation and its significance on carcinogenesis. (2010) (52)
- Methylation silencing of transforming growth factor-beta receptor type II in rat prostate cancers. (2008) (51)
- Marked and independent prognostic significance of the CpG island methylator phenotype in neuroblastomas. (2007) (51)
- Down‐regulated expression of prostasin in high‐grade or hormone‐refractory human prostate cancers (2003) (50)
- Promoter hypermethylation and post-transcriptional mechanisms for reduced BRCA1 immunoreactivity in sporadic human breast cancers. (2002) (50)
- Identification of Genes Targeted by CpG Island Methylator Phenotype in Neuroblastomas, and Their Possible Integrative Involvement in Poor Prognosis (2008) (50)
- WNT Pathway Gene Mutations Are Associated With the Presence of Dysplasia in Colorectal Sessile Serrated Adenoma/Polyps (2017) (50)
- DNA Methylation of MicroRNA-124a Is a Potential Risk Marker of Colitis-Associated Cancer in Patients with Ulcerative Colitis (2014) (48)
- Expression of the intestine-specific transcription factors, Cdx1 and Cdx2, correlates shift to an intestinal phenotype in gastric cancer cells (2003) (47)
- Frequent involvement of chromatin remodeler alterations in gastric field cancerization. (2015) (47)
- Decreased fidelity in replicating CpG methylation patterns in cancer cells. (2005) (47)
- DNA methylation: a marker for carcinogen exposure and cancer risk (2008) (46)
- Global expression analysis of N-methyl-N'-nitro-N-nitrosoguanidine-induced rat stomach carcinomas using oligonucleotide microarrays. (2003) (46)
- Silencing of tissue factor pathway inhibitor‐2 gene in malignant melanomas (2007) (45)
- Methylation and expression analysis of 15 genes and three normally-methylated genes in 13 Ovarian cancer cell lines. (2006) (45)
- Effects of gender and species on spectra of mutation induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in the lacI transgene. (1997) (45)
- Mutation induction by okadaic acid, a protein phosphatase inhibitor, in CHL cells, but not in S. typhimurium. (1991) (45)
- Cancer cell niche factors secreted from cancer-associated fibroblast by loss of H3K27me3 (2019) (44)
- High impact of methylation accumulation on metachronous gastric cancer: 5-year follow-up of a multicentre prospective cohort study (2016) (44)
- Absence of p53 Mutations in Rat Colon Tumors Induced by 2‐Amino‐6‐methyldipyrido[1,2‐a:3′, 2′‐d]imidazole, 2‐Amino‐3‐methylimidazo[4,5‐f]quinoline, or 2‐Amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (1994) (44)
- Rare frequency of activation of the ki‐ras gene in rat colon tumors induced by heterocyclic amines: Possible alternative mechanisms of human colon carcinogenesis (1993) (44)
- Identification of PRTFDC1 silencing and aberrant promoter methylation of GPR150, ITGA8 and HOXD11 in ovarian cancers. (2007) (44)
- Dependence receptor UNC5D mediates nerve growth factor depletion-induced neuroblastoma regression. (2013) (44)
- Hippocampal epigenetic modification at the doublecortin gene is involved in the impairment of neurogenesis with aging (2010) (43)
- Frequent mutations of the rat β‐catenin gene in colon cancers induced by methylazoxymethanol acetate plus 1‐hydroxyanthraquinone (1999) (43)
- Infrequent mutation of ha‐ras and p53 in rat mammary carcinomas induced by 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (1994) (43)
- Human exposure to carcinogenic heterocyclic amines and their mutational fingerprints in experimental animals. (1996) (43)
- Reduced expression of the insulin‐induced protein 1 and p41 Arp2/3 complex genes in human gastric cancers (2002) (43)
- A rat genetic map constructed by representational difference analysis markers with suitability for large-scale typing. (1996) (43)
- FHL1 on chromosome X is a single-hit gastrointestinal tumor-suppressor gene and contributes to the formation of an epigenetic field defect (2013) (42)
- Etiology-specific gene expression profiles in rat mammary carcinomas. (2002) (40)
- Development of a Novel Output Value for Quantitative Assessment in Methylated DNA Immunoprecipitation-CpG Island Microarray Analysis (2009) (40)
- Expression Quantitative Trait Loci Analysis of 13 Genes in the Rat Prostate (2005) (39)
- A rapid method for detection of mutations in the lacI gene using PCR-single strand conformation polymorphism analysis: demonstration of its high sensitivity. (1995) (38)
- Cloning of the rat agouti gene and identification of the rat nonagouti mutation (2001) (38)
- Induction of aberrant crypt foci in C57BL/6N mice by 2-amino-9H-pyrido[2,3-b]indole (A alphaC) and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx). (1997) (37)
- LacI transgenic animal study: relationships among DNA-adduct levels, mutant frequencies and cancer incidences. (2001) (37)
- Development of a novel approach, the epigenome-based outlier approach, to identify tumor-suppressor genes silenced by aberrant DNA methylation. (2012) (36)
- p53 Gene Mutations in Human Prostate Cancers in Japan: Different Mutation Spectra between Japan and Western Countries (1994) (36)
- Demonstration of ras and p53 Gene Mutations in Carcinomas in the Forestomach and Intestine and Soft Tissue Sarcomas Induced by N‐Methyl‐N‐nitrosourea in the Rat (1997) (36)
- A tissue microRNA signature that predicts the prognosis of breast cancer in young women (2017) (36)
- Visualization of multivalent histone modification in a single cell reveals highly concerted epigenetic changes on differentiation of embryonic stem cells (2013) (35)
- Tissue-specific mutational spectra of 2-amino-3,4-dimethylimidazo[4,5-f]quinoline in the liver and bone marrow of lacI transgenic mice. (1994) (35)
- Introduction: epigenetics and cancer. (2010) (35)
- GERM CELL TUMOURS (2014) (35)
- Microsatellite instability and loss of heterozygosity on chromosome 10 in rat mammary tumors induced by 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (1996) (34)
- BRCA2 germline mutations in Japanese breast cancer families (1997) (33)
- Association between frequent CpG island methylation and HER2 amplification in human breast cancers. (2009) (33)
- Hereditary diffuse gastric cancer in a Japanese family with a large deletion involving CDH1 (2014) (33)
- Genetic alterations in rat colon tumors induced by heterocyclic amines (1996) (33)
- Novel epigenetic markers for gastric cancer risk stratification in individuals after Helicobacter pylori eradication (2018) (33)
- Interpretation of mutational spectra from different genes: analyses of PhIP-induced mutational specificity in the lacI and cII transgenes from colon of Big Blue rats. (2000) (33)
- Framework Analysis for the Carcinogenic Mode of Action of Nitrobenzene (2007) (32)
- Adenomatous polyposis coli 1A is likely to be methylated as a passenger in human gastric carcinogenesis. (2009) (31)
- Induction of aberrant trimethylation of histone H3 lysine 27 by inflammation in mouse colonic epithelial cells. (2012) (30)
- Microsatellite instability in latent prostate cancers (1996) (29)
- Identification of gastric cancer risk markers that are informative in individuals with past H. pylori infection (2012) (29)
- Fibroblasts associated with cancer cells keep enhanced migration activity after separation from cancer cells: a novel character of tumor educated fibroblasts. (2010) (29)
- Estimation of the Fraction of Cancer Cells in a Tumor DNA Sample Using DNA Methylation (2013) (29)
- Cloning of the 5’Upstream Region of the Rat p16 Gene and Its Role in Silencing (2002) (28)
- Whole‐genome analyses of loss of heterozygosity and methylation analysis of four tumor‐suppressor genes in N‐methyl‐N′‐nitro‐N‐nitrosoguanidine‐induced rat stomach carcinomas (2005) (28)
- Altered mucosal DNA methylation in parallel with highly active Helicobacter pylori-related gastritis (2013) (27)
- TET repression and increased DNMT activity synergistically induce aberrant DNA methylation. (2020) (27)
- PRC2-Mediated Transcriptomic Alterations at the Embryonic Stage Govern Tumorigenesis and Clinical Outcome in MYCN-Driven Neuroblastoma. (2017) (27)
- Gene expression profiling distinguishes between spontaneous and radiation-induced rat mammary carcinomas. (2008) (26)
- The presence of single nucleotide instability in human breast cancer cell lines. (2001) (26)
- Single nucleotide instability without microsatellite instability in rat mammary carcinomas. (2001) (26)
- Epigenetic inactivation of FAT4 contributes to gastric field cancerization (2016) (26)
- Methylation of multiple genes in gastric glands with intestinal metaplasia: A disorder with polyclonal origins. (2006) (26)
- Association of gastric cancer risk factors with DNA methylation levels in gastric mucosa of healthy Japanese: a cross-sectional study. (2015) (26)
- Establishment of a DNA methylation marker to evaluate cancer cell fraction in gastric cancer (2016) (25)
- Difference in Target Organs in Carcinogenesis with a Heterocyclic Amine, 2‐Amino‐3,4‐dimethylimidazo[4,5‐f]quinoline, in Different Strains of Mice (1999) (25)
- β‐Catenin mutations and nuclear accumulation during progression of rat stomach adenocarcinomas (2003) (25)
- Insertional mutation of the Attractin gene in the black tremor hamster (2001) (25)
- Studies on mammary carcinogenesis induced by a heterocyclic amine, 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine, in mice and rats (2002) (25)
- Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells (2019) (24)
- No involvement of Ki‐ras or p53 gene mutations in colitis‐associated rat colon tumors induced by 1‐hydroxyanthraquinone and methylazoxymethanol acetate (1995) (24)
- The Myelin Vacuolation (mv) Rat with a Null Mutation in the Attractin Gene (2002) (24)
- Antibiotics suppress colon tumorigenesis through inhibition of aberrant DNA methylation in an azoxymethane and dextran sulfate sodium colitis model (2018) (24)
- No direct correlation between mutant frequencies and cancer incidence induced by MeIQ in various organs of Big Blue mice. (1998) (24)
- Integrated analysis of DNA methylation and mutations in esophageal squamous cell carcinoma (2016) (23)
- Silencing of the thrombomodulin gene in human malignant melanoma (2005) (23)
- Identification of 29 Rat Genetic Markers by Arbitrarily Primed Polymerase Chain Reaction (1996) (23)
- Value of KRAS, BRAF, and PIK3CA Mutations and Survival Benefit from Systemic Chemotherapy in Colorectal Peritoneal Carcinomatosis. (2016) (23)
- Identification of a DNA methylation marker that detects the presence of lymph node metastases of gastric cancers. (2012) (22)
- PRECLINICAL STUDY: BRIEF REPORT: Epigenetic modulation at the CCR2 gene correlates with the maintenance of behavioral sensitization to methamphetamine (2010) (22)
- Targeting of super-enhancers and mutant BRAF can suppress growth of BRAF-mutant colon cancer cells via repression of MAPK signaling pathway. (2017) (22)
- Methylation destiny: Moira takes account of histones and RNA polymerase II (2010) (21)
- neu proto-oncogene mutation is specific for the neurofibromas in a N-nitroso-N-ethylurea-induced hamster neurofibromatosis model but not for hamster melanomas and human Schwann cell tumors. (1994) (21)
- Chronic treatment of non-small-cell lung cancer cells with gefitinib leads to an epigenetic loss of epithelial properties associated with reductions in microRNA-155 and -200c (2017) (21)
- High-risk oral leukoplakia is associated with aberrant promoter methylation of multiple genes (2016) (21)
- Linkage and microarray analyses of susceptibility genes in ACI/Seg rats: a model for prostate cancers in the aged. (2005) (21)
- Development of an integrated CRISPRi targeting ΔNp63 for treatment of squamous cell carcinoma (2018) (21)
- Comprehensive DNA Methylation and Extensive Mutation Analyses of HER2-Positive Breast Cancer (2015) (21)
- Down‐regulation of human X‐box binding protein 1 (hXBP‐1) expression correlates with tumor progression in human prostate cancers (2002) (21)
- Suppressive effect of global DNA hypomethylation on gastric carcinogenesis. (2010) (20)
- Methylation silencing of angiopoietin‐like 4 in rat and human mammary carcinomas (2011) (20)
- Mutation, loss of heterozygosity, and recombination of the p53 gene in mouse forestomach tumors induced by 2‐amino‐3,4‐dimethylimidazo[4,5‐f]quinoline (1995) (20)
- Genome‐wide analysis of DNA methylation changes induced by gestational arsenic exposure in liver tumors (2013) (20)
- Three-Component Repurposed Technology for Enhanced Expression: Highly Accumulable Transcriptional Activators via Branched Tag Arrays (2018) (20)
- Epigenetic priming sensitizes gastric cancer cells to irinotecan and cisplatin by restoring multiple pathways (2019) (20)
- RNF208, an estrogen-inducible E3 ligase, targets soluble Vimentin to suppress metastasis in triple-negative breast cancers (2019) (19)
- Profiling and selection of genes differentially expressed in the pylorus of rat strains with different proliferative responses and stomach cancer susceptibility. (2002) (19)
- Imagine a world without cancer (2014) (19)
- Targeting aberrant DNA hypermethylation as a driver of ATL leukemogenesis using the new oral demethylating agent OR-2100. (2020) (19)
- Persistence of gene expression changes in stomach mucosae induced by short-term N-methyl-N'-nitro-N-nitrosoguanidine treatment and their presence in stomach cancers. (2004) (19)
- Ki‐ras Activation in Pancreatic Carcinomas of Syrian Hamsters Induced by N‐Nitrosobis(2‐hydroxypropyl)amine (1991) (19)
- Larger numbers of silenced genes in cancer cell lines with increased de novo methylation of scattered CpG sites. (2007) (19)
- Chromosomal mapping of genes controlling development, histological grade, depth of invasion, and size of rat stomach carcinomas. (2000) (19)
- RUNX3 expression correlates with chief cell differentiation in human gastric cancers. (2009) (18)
- ZNF695 methylation predicts a response of esophageal squamous cell carcinoma to definitive chemoradiotherapy (2015) (18)
- Mapping genomic and epigenomic evolution in cancer ecosystems (2021) (18)
- Pathological complete response of HER2-positive breast cancer to trastuzumab and chemotherapy can be predicted by HSD17B4 methylation (2017) (18)
- Systemic Administration of Small Interfering RNA Targeting Human Nestin Inhibits Pancreatic Cancer Cell Proliferation and Metastasis (2016) (18)
- Novel prodrugs of decitabine with greater metabolic stability and less toxicity (2019) (18)
- Hypomethylation of Alu repetitive elements in esophageal mucosa, and its potential contribution to the epigenetic field for cancerization (2012) (18)
- Identification and Validation of DNA Methylation Markers to Predict Lymph Node Metastasis of Esophageal Squamous Cell Carcinomas (2011) (18)
- Effects of genome architecture and epigenetic factors on susceptibility of promoter CpG islands to aberrant DNA methylation induction. (2011) (17)
- Presacral malignant teratoid neoplasm in association with pathogenic DICER1 variation (2019) (17)
- DNA adduct level induced by 2-amino-3,4-dimethylimidazo[4,5-f]-quinoline in Big Blue mice does not correlate with mutagenicity. (1998) (17)
- Epigenetic reprogramming underlies efficacy of DNA demethylation therapy in osteosarcomas (2019) (17)
- MACON: a web tool for computing DNA methylation data obtained by the Illumina Infinium Human DNA methylation BeadArray. (2018) (17)
- Metabolomic profiling reveals salivary hypotaurine as a potential early detection marker for medication-related osteonecrosis of the jaw (2019) (17)
- Genetic alterations in HCA-induced tumors. (1995) (17)
- Down-regulation of Lsm1 is involved in human prostate cancer progression (2002) (16)
- Establishment of a detection system for demethylating agents using an endogenous promoter CpG island. (2004) (16)
- Clinical application of the CpG island methylator phenotype to prognostic diagnosis in neuroblastomas (2013) (16)
- Beta-catenin mutations in liver tumors induced by 2-amino-3,4-dimethylimidazo[4,5-f]quinoline in CDF1 mice. (2003) (16)
- Rare mutations of p53, Ki‐ras, and β‐catenin genes and absence of K‐sam and c‐erbB‐2 amplification in N‐methyl‐N′‐N‐nitrosoguanidine–induced rat stomach cancers (1999) (16)
- Genome-wide DNA methylation profiling identifies primary central nervous system lymphoma as a distinct entity different from systemic diffuse large B-cell lymphoma (2017) (16)
- Distinct DNA methylation targets by aging and chronic inflammation: a pilot study using gastric mucosa infected with Helicobacter pylori (2019) (16)
- Linkage Analysis of BRCA1 in Japanese Breast Cancer Families (1994) (15)
- Dose-dependent roles for canonical Wnt signalling in de novo crypt formation and cell cycle properties of the colonic epithelium (2013) (15)
- Early-Stage Induction of SWI/SNF Mutations during Esophageal Squamous Cell Carcinogenesis (2016) (15)
- No involvement of APC gene mutations in ulcerative colitis–associated rat colon carcinogenesis induced by 1‐hydroxyanthraquinone and methylazoxymethanol acetate (1997) (15)
- Mapping of A gene responsible for cataract formation and its modifier in the UPL rat. (2002) (15)
- Risk stratification for gastric cancer after Helicobacter pylori eradication: A population‐based study on Matsu Islands (2020) (14)
- LINC00162 confers sensitivity to 5-Aza-2′-deoxycytidine via modulation of an RNA splicing protein, HNRNPH1 (2019) (13)
- Epigenetic field for cancerization: its cause and clinical implications (2013) (13)
- Molecular characterization of cancer reveals interactions between ionizing radiation and chemicals on rat mammary carcinogenesis (2014) (13)
- Clinicopathological and molecular correlations in traditional serrated adenoma (2020) (13)
- Degree of methylation burden is determined by the exposure period to carcinogenic factors (2017) (12)
- Invasive breast cancers in adolescent and young adult women show more aggressive immunohistochemical and clinical features than those in women aged 40–44 years (2018) (12)
- Single nucleotide instability: a wide involvement in human and rat mammary carcinogenesis? (2002) (12)
- Mutation induction by mechanical irritation caused by uracil-induced urolithiasis in Big Blue rats. (2000) (12)
- Genetic determinant and environmental carcinogens. (1998) (12)
- Decreased fidelity in replicating DNA methylation patterns in cancer cells leads to dense methylation of a CpG island. (2006) (11)
- Absence of ras Family Point Mutations at Codons 12, 13 and 61 in N‐Ethyl‐N‐hydroxyethylnitrosamine‐ or N‐Nitrosomorpholine‐induced Renal Cell Tumors in Rats (1992) (11)
- The Absence of Mth1 Inactivation and DNA Polymerase k Overexpression in Rat Mammary Carcinomas with Frequent A:T to C:G Transversions (2002) (11)
- Construction of a phylogenetic tree for inbred strains of rat by arbitrarily primed polymerase chain reaction (AP-PCR) (1995) (11)
- Stronger prognostic power of the CpG island methylator phenotype than methylation of individual genes in neuroblastomas. (2013) (11)
- Epigenetic biomarkers: New findings, perspectives and future directions in diagnostics (2016) (10)
- SAA1 is upregulated in gastric cancer-associated fibroblasts possibly by its enhancer activation. (2020) (10)
- Atypical medullary carcinoma of the breast with cartilaginous metaplasia in a patient with a BRCA1 germline mutation. (2000) (10)
- Exclusive KRAS mutation in microsatellite-unstable human colorectal carcinomas with sequence alterations in the DNA mismatch repair gene, MLH1. (2008) (10)
- Closely Linked Polymorphic Markers for Determining the Autosomal Dominant Allele (Cy) in Rat Polycystic Kidney Disease (1999) (10)
- Presence of p53 Mutations in 3Y1‐B Clone 1‐6: A Rat Cell Line Widely Used as a Normal Immortalized Fibroblast (1994) (10)
- Cancer epigenetics: now harvesting fruit and seeding for common diseases. (2014) (10)
- RHOA mutation may be associated with diffuse-type gastric cancer progression, but is it gain or loss? (2016) (10)
- Full length and delta lactoferrin display differential cell localization dynamics, but do not act as tumor markers or significantly affect the expression of other genes. (2005) (10)
- Methylation-sensitive representational difference analysis (MS-RDA). (2009) (10)
- Linkage disequilibrium pattern in the L‐myc gene in Italian and Japanese non‐small‐cell lung‐cancer patients (2001) (9)
- Cell-specific overexpression of COMT in dopaminergic neurons of Parkinson's disease. (2019) (9)
- Development of the arbitrarily primed-representational difference analysis method and chromosomal mapping of isolated high throughput rat genetic markers. (1999) (9)
- Establishment of a high-throughput detection system for DNA demethylating agents (2018) (9)
- Differential expression of genes related to levels of mucosal cell proliferation among multiple rat strains by using oligonucleotide microarrays (2003) (9)
- [Human ret proto-oncogene]. (1990) (9)
- Cloning and activation of the Syrian hamster neu proto-oncogene. (1994) (9)
- Multi-omics analyses identify HSD17B4 methylation-silencing as a predictive and response marker of HER2-positive breast cancer to HER2-directed therapy (2020) (8)
- DNA methylation marker to estimate the breast cancer cell fraction in DNA samples (2018) (8)
- Isolation of 48 genetic markers appropriate for high throughput genotyping of inbred rat strains by B1 repetitive sequence-representational difference analysis (1998) (8)
- A 5'-region polymorphism modulates promoter activity of the tumor suppressor gene MFSD2A (2011) (8)
- 12p gain is predominantly observed in non-germinomatous germ cell tumors and identifies an unfavorable subgroup of central nervous system germ cell tumors. (2021) (8)
- Genetic mapping of the RET protooncogene on rat Chromosome 4 (1995) (8)
- Significance of molecular classification of ependymomas: C11orf95-RELA fusion-negative supratentorial ependymomas are a heterogeneous group of tumors (2018) (7)
- Analysis of DNA Methylation in Tissues Exposed to Inflammation. (2018) (7)
- BRAF inhibitor: a novel therapy for ameloblastoma in mandible (2018) (7)
- The Origin of CIMP, At Last. (2019) (7)
- Rare Activation of the Human c‐Ha‐ras Transgene of Mice in Hemangioendothelial Sarcomas and Liver Tumors Induced by Glu‐P‐1 (1996) (7)
- Low-dose DNA demethylating therapy induces reprogramming of diverse cancer-related pathways at the single-cell level (2020) (7)
- FGF5 methylation is a sensitivity marker of esophageal squamous cell carcinoma to definitive chemoradiotherapy (2019) (7)
- BRCA1 andBRCA2 germline mutations in Japanese with hereditary breast cancer families (1997) (7)
- A high phosphorylation state and increased activity of the TRE motif in the NIH3T3 cell transformant induced by retTPC. (1991) (6)
- Pancreatic Cancer Cell Fraction Estimation in a DNA Sample (2018) (6)
- The Moment that KRAS Mutation Started to Evolve into Precision Medicine in Metastatic Colorectal Cancer. (2016) (6)
- Generation of a polymorphic marker linked to thymoma susceptibility gene of rat 1 by genetically-directed representational difference analysis. (2000) (6)
- Targeting DNMT1 by demethylating agent OR-2100 increases tyrosine kinase inhibitors-sensitivity and depletes leukemic stem cells in chronic myeloid leukemia. (2021) (6)
- BRCA1 promoter methylation in breast cancer patients is associated with response to olaparib/eribulin combination therapy (2020) (6)
- A novel method to quantify base substitution mutations at the 10-6 per bp level in DNA samples. (2017) (6)
- Co-expression of ERG and CD31 in a subset of CIC-rearranged sarcoma: a potential diagnostic pitfall (2022) (5)
- Methylation changes and aberrant expression of FGFR3 in Lewy body disease neurons (2018) (5)
- Influence of degree of DNA degradation in formalin-fixed and paraffin-embedded tissue samples on accuracy of genome-wide DNA methylation analysis. (2021) (5)
- Sparse and wavy hair: a new model for hypoplasia of hair follicle and mammary glands on rat chromosome 17. (2005) (5)
- Epigenetics is a fascinating field of modern biology. Preface. (2010) (5)
- Identification of a metastatic lung adenocarcinoma of the palate mucosa through genetic and histopathological analysis: a rare case report and literature review (2019) (5)
- Analysis of Gene-specific DNA Methylation (2011) (5)
- Genetic and epigenetic profiling indicates the proximal tubule origin of renal cancers in end‐stage renal disease (2020) (5)
- Construction of a high-throughput rat genetic mapping system with 466 arbitrarily primed-representational difference analysis markers (2000) (5)
- Cancer Epigenetics (2019) (4)
- Comparison of involved field radiotherapy and elective nodal irradiation in combination with concurrent chemotherapy for T1bN0M0 esophageal cancer (2020) (4)
- Methylation-associated silencing of four genes in human pancreatic cancers (2004) (4)
- Overexpression of PIK 3 CA is associated with lymph node metastasis in esophageal squamous cell carcinoma (4)
- Reduced Brca1 protein expression in 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine–induced rat mammary carcinomas (2002) (4)
- Cyclin D1 overexpression in N-methyl-N'-nitro-N-nitrosoguanidine-induced rat gastric adenocarcinomas. (2007) (4)
- DNA methylation genome-wide analysis in remnant and primary gastric cancers (2019) (4)
- [Genetic and epigenetic alterations in gastric carcinogenesis]. (2012) (4)
- Genetic polymorphisms and susceptibility to cancer development. (1995) (4)
- Increased H-ras mutation frequency in mammary tumors of rats initiated with N-methyl-N-nitrosourea (MNU) and treated with acrylamide. (2009) (3)
- Generation of polymorphic markers tightly linked to the thymus enlargement loci by phenotype-directed representational difference analysis (1998) (3)
- cDNA cloning of the rat APC gene and assignment to Chromosome 18 (1995) (3)
- Aberrant DNA Methylation in Cancer Cells (2010) (3)
- Epigenetic Epidemiology of Infectious Diseases (2012) (3)
- Silylation of Deoxynucleotide Analog Yields an Orally Available Drug with Antileukemia Effects (2021) (3)
- Linkage mapping of the rat Tp53 gene on Chromosome 10 (1996) (3)
- EGFR L2 domain mutation is not correlated with resistance to cetuximab in metastatic colorectal cancer patients (2013) (3)
- Isolation of a Genetic Marker Linked to the Bh Gene by Genetically Directed Representational Difference Analysis of Closed Colony Japanese Quails (2001) (3)
- Histone modification of pain-related gene expression in spinal cord neurons under a persistent postsurgical pain-like state by electrocautery (2021) (2)
- [Epigenetics as a novel therapeutic target of cancer]. (2013) (2)
- Iconographies supplémentaires de l'article : 276 Incidence and Risk Factors of Metachronous Gastric Cancer After Endoscopic Resection and Successful Helicobacter pylori Eradication: Results From a Large-Scale, Multicenter Cohort Study in Japan (2015) (2)
- 276 Incidence and Risk Factors of Metachronous Gastric Cancer After Endoscopic Resection and Successful Helicobacter pylori Eradication: Results From a Large-Scale, Multicenter Cohort Study in Japan (2014) (2)
- MicroRNAs and epigenetics in human breast cancer. (2009) (2)
- Molecular mechanisms of gastric carcinogenesis. (2016) (2)
- Autoimmune gastritis induces aberrant DNA methylation reflecting its carcinogenic potential (2022) (2)
- Molecular and Cellular Pathobiology Cancer Research Inflammatory Processes Triggered by Helicobacter pylori Infection Cause Aberrant DNA Methylation in Gastric Epithelial Cells (2010) (2)
- A quantification method of somatic mutations in normal tissues and their accumulation in pediatric patients with chemotherapy (2022) (2)
- Predictive value of genetic analysis for pathological complete response to preoperative treatment in HER2 positive, HR negative early breast cancer (PASSION trial). (2018) (2)
- Japanese late-onset breast cancer families: Their clinicopathological characteristics and absence ofBRCA1 andBRCA2 germline mutations (1998) (2)
- [DNA methylation and cancer--DNA methylation as a target of cancer chemotherapy]. (2003) (2)
- Abstract 3056: Development of an integrated CRISPR interference system targeting ΔNp63 to treat lung and esophageal squamous cell carcinoma (2019) (1)
- Abstract 5340: The methylation burden is determined by the duration of exposure to carcinogenic factors (2018) (1)
- Cloning of rat Brca2 and linkage mapping to Chromosome 12 (2009) (1)
- Clinicopathological and genetic features of limited-stage diffuse large B-cell lymphoma with late relapse: targeted sequencing analysis of gene alterations in the initial and late relapsed tumors (2020) (1)
- Does aberrant DNA methylation occur in human uterine leiomyomas? An attempt of genome-wide screening by MS-RDA. (2011) (1)
- Genetic alterations in rat colon tumors induced by heterocyclic amines (1)
- [Global understanding of pain]. (2012) (1)
- Bilateral breast cancer in a patient with a strong family history of cancer: Analysis of p53 germ line mutations (1994) (1)
- Linkage Mapping of the Bra, Brb and Brg Genes for Rat Protein Phosphatase 2A 55 kDa B‐Regulatory Subunit Isotypes (1998) (1)
- Cancers Methylation and Loss of Heterozygosity in Human Gastric Is a Tumor Suppressor Gene Inactivated by Lysyl Oxidase (2004) (1)
- Linkage mapping of rat Rb1 gene on Chromosome 15 (1997) (1)
- human CML -expressing hematopoietic cells: a transgenic study for blast crisis of Acquired loss of p53 induces blastic transformation in p210 bcr/abl (2013) (1)
- Chapter 8 – Analysis of Gene-Specific DNA Methylation (2017) (1)
- Electronic supplementary material Epigenetic Inactivation of FAT 4 Contributes to Gastric Field Cancerization (1)
- [Epigenetic Alterations in Gastrointestinal Cancers: Diagnostic and Therapeutic Applications]. (2018) (1)
- Prediction of tissue origin of adenocarcinomas in the esophagogastric junction by DNA methylation (2021) (1)
- [Application of epigenetics to cancer diagnosis and therapy]. (2012) (1)
- 98PBRCA1 methylation in triple-negative breast cancer (2015) (1)
- DNA methylation marker to estimate ovarian cancer cell fraction (2021) (1)
- Abstract 430: Identification of novel methylation-silenced genes in oral squamous cell carcinomas (2014) (1)
- RUNX3 Suppresses Gastric Epithelial Cell Growth by Inducing p21 Expression in Cooperation with Transforming Growth Factor (cid:2) -Activated SMAD (2005) (1)
- Comprar Advances In Genetics, Vol. 70: Epigenetics And Cancer, Part A | Z. Herceg | 9780123808660 | Academic Press (2010) (1)
- ARID1A loss-of-function induces CpG island methylator phenotype. (2022) (1)
- Imagine a world without cancer (2014) (1)
- Susceptibility and resistance genes to MNNG-induced stomach carcinogenesis (1999) (1)
- Phase I study of tamibarotene monotherapy in pediatric and young adult patients with recurrent/refractory solid tumors (2021) (1)
- Linkage mapping of the rat interleukin 1 receptor antagonist gene on chromosome 3. (2001) (1)
- [Genes involved in breast cancers]. (2006) (1)
- DNA methylation of the immediate upstream region of BRCA1 major transcription start sites is an independent favorable prognostic factor in patients with high-grade serous ovarian cancer. (2022) (1)
- Abstract LB-245: Preclinical study of epigenetic drug-based differentiation therapy for neuroblastoma (2016) (1)
- Methylation silencing of ULK2 via epithelial–mesenchymal transition causes transformation to poorly differentiated gastric cancers (2021) (1)
- Relationship between methylation status of PTEN and point mutation of the EGFR L2 domain and efficacy of cetuximab in metastatic colorectal cancer. (2011) (1)
- Linkage mapping of the rat Msh2 DNA mismatch repair gene on chromosome 6. (1999) (1)
- Mutagenicity of okadaic acid on cultured Chinese hamster cells (1991) (1)
- Correction to: Epigenetic priming sensitizes gastric cancer cells to irinotecan and cisplatin by restoring multiple pathways (2019) (1)
- Mechanisms of DNA Methylation Changes in Cancer (2018) (1)
- Abstract 2169: FHL1 on chromosome X is a single-hit gastrointestinal tumor-suppressor gene and contributes to the formation of an epigenetic field defect (2012) (0)
- Environmental mutagen society of Japan selected abstracts of the 23rd annual meeting (1996) (0)
- 1406PIncreased mutation burden in high-risk lung tissues: Toward precision cancer risk diagnosis (2017) (0)
- Contents Vol. 64, 2003 (2003) (0)
- EP-02MOLECULAR CLASSIFICATION OF EPENDYMOMAS IN A JAPANESE COHORT (2015) (0)
- MeIQ in vivo mutagenesis: Mutational spectra in organs with or without cancer development (1996) (0)
- Perspectives and future directions of translational epigenetics in personalized and precision medicine (2022) (0)
- Receptor Type II in Rat Prostate Cancers β Methylation Silencing of Transforming Growth Factor-Updated (2008) (0)
- Suppression of Tet genes by chronic inflammation and aberrant DNA methylation induction (2016) (0)
- Genomics of Limited-Stage Diffuse Large B-Cell Lymphoma Developing Late Relapse: Analysis of Gene Alterations in Paired Primary and Late Relapsed Tumors By Target Sequencing (2018) (0)
- Depletion of R270C Mutant p53 in Osteosarcoma Attenuates Cell Growth but Does Not Prevent Invasion and Metastasis In Vivo (2022) (0)
- Abstract LB-176: Identification of DNA methylation markers to predict esophageal cancer risk for people with carcinogen exposure (2014) (0)
- Specifi ' c 5 '-GGGA-3 '-* 5 '-GGA-3 ' mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo [ 4 , 5b ] pyridine ( colorectal neoplasms / heterocyclic amines / fingerprinting ) (2005) (0)
- Combination of a synthetic retinoid and a DNA demethylating agent induced differentiation of neuroblastoma through retinoic acid signal reprogramming (2021) (0)
- Procedures for assessing the verkrebsungsgrades (2004) (0)
- Abstract LB-378: The outlier approach discriminates drivers from passengers among genes methylated in cancers (2012) (0)
- OR21, a New Oral DNA Methyltransferase Inhibitor for Treatment of MDS and AML (2018) (0)
- Novel prodrugs of decitabine with greater metabolic stability and less toxicity (2019) (0)
- Chronic ethanol treatment alters the central gene-expression profiling along with epigenetic modifications (2010) (0)
- PD49-03 GENETIC AND EPIGENETIC PROFILING INDICATES THE PROXIMAL TUBULE ORIGIN OF RENAL CANCERS IN END-STAGE RENAL DISEASE (2021) (0)
- Abstract 5331: Repression ofTETgenes and enhancement of DNA methyltransferase activity are critical for induction of aberrant DNA methylation (2018) (0)
- Abstract 838: Epigenetic reprogramming of different cancer-related pathways at the single cell level after low-dose DNA demethylation therapy (2019) (0)
- Meeting Report of the Fifth International Cancer Epigenetics Conference in Beijing, China, October 2016. (2017) (0)
- Abstract 4460: Precision cancer risk diagnosis by accumulation of epigenetic alterations (2016) (0)
- Contribution of genetic and epigenetic alteration to cancer risk is different in different tissues (2016) (0)
- Analysis of dopaminergic dysfunction-related molecules in the developmental stage of Parkinson’s disease using human disease-specific iPS cells (2017) (0)
- ISY4-4What is a useful biomarker for advanced gastric cancer (AGC)? (2015) (0)
- Histone modification of pain-related gene expression in spinal cord neurons under a persistent postsurgical pain-like state by electrocautery (2021) (0)
- Comprehensive analysis of epigenetic modification under a persistent postoperative pain-like state (2021) (0)
- Mo1557 DNA Methylation in Gastric Mucosae is Associated With the Severity of Mucosal Inflammation Involving the Risk of Diffuse-Type Gastric Cancer (2012) (0)
- Abstract 1079: Distinct DNA methylation targets by aging and chronic inflammation (2020) (0)
- Comparable genetic alteration profiles between gastric cancers with current and past Helicobacter pylori infection (2021) (0)
- Subject Index Vol. 64, 2003 (2003) (0)
- Gastric Cancer Risk Prediction Using Epigenetic Alterations Accumulated in Noncancerous Gastric Tissues (2018) (0)
- Abstract 6005: Promoter methylation occurs at high frequencies regardless of mutation status of tumor-associated genes in oral malignancies (2023) (0)
- Progression patterns and site-specific responses in advanced gastric cancer patients treated with nivolumab. (2023) (0)
- Abstract 4239: Development of DNA methylation markers to estimate the fraction of tumor cells in DNA samples. (2013) (0)
- [Genetic alterations and expression changes in breast cancers]. (2007) (0)
- Correction: Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells (2022) (0)
- Abstract 843: Epigenomic disruption of adipogenic regulators in dedifferentiated liposarcoma (2019) (0)
- Editorial Board and Contents (2015) (0)
- Abstract #LB-165: Association between frequent CpG island methylation and HER2 amplification in human breast cancers (2009) (0)
- Development of a Web tool, Macon, for analysis of DNA methylation data obtained by Illumina beadchip. (2016) (0)
- Attractin y Mahogany y Zitter plays a critical role in myelination of the central nervous system (2001) (0)
- Clinicopathological features, genetic alterations, and BRCA1 promoter methylation in Japanese male patients with breast cancer (2022) (0)
- Abstract 2314: The combination of DNA methylation and H3K27me3 is a cancer-specific dual epigenetic modification (2014) (0)
- Abstract 921: Cdyl2 is a chromodomain protein involved in the maintenance of pluripotency of stem cells (2017) (0)
- Abstract 3892: Inhibitory effects and regulatory mechanism of nestin in pancreatic cancer (2014) (0)
- Abstract 6015: Methylation synthetic lethality: CHFR methylation and KRAS inhibition in gastric cancers (2023) (0)
- For Peer Review Induction of aberrant trimethylation of histone H3 lysine 27 by inflammation in mouse colonic epithelial cells (2012) (0)
- NEURON-SPECIFIC METHYLOME ANALYSIS REVEALS NEW PATHOMECHANISM IN ALZHEIMER’S DISEASE BRAINS (2016) (0)
- Abstract 819: DNA methylation genome-wide analysis in remnant gastric cancer (2019) (0)
- PB1701 OR21, A NEWLY ORAL DECITABINE PRODRUG, HAS ANTI-TUMOR EFFECT AGAISNT MYELODYSPLASTIC SYNDROME AND ACUTE MYELOID LEUKEMIA VIA CELL DIFFERENTIATION INDUCED BY UP-REGULATION OF CEBPE (2019) (0)
- Analysis for molecular mechanism of hippocampal neurogenesis associated with epigenetic modulation under enriched environment (2011) (0)
- Molecular Pathways Molecular Pathways : Involvement of Helicobacter pylori – Triggered In fl ammation in the Formation of an Epigenetic Field Defect , and Its Usefulness as Cancer Risk and Exposure Markers (2012) (0)
- Abstract 2002: Prevention of gastric cancers induced byHelicobacter pyloriinfection with a DNA demethylating reagent, 5-aza-2′-deoxycytidine (2011) (0)
- Abstract 4260: Increased mutation burden in normal-appearing lung tissues with high cancer risk (2017) (0)
- 382. PREDICTION OF ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC) RISK BY ASSESSING EPIGENETIC AND GENETIC FIELD DEFECTS (2022) (0)
- Development of novel DNA demethylating agents with greater stability and less toxicity (2016) (0)
- Abstracts of the 23rd Annual Meeting of the Japanese Society for Pigment Cell Research. November 27-28, 2010. Tokyo, Japan. (2010) (0)
- Identification of a metastatic lung adenocarcinoma of the palate mucosa through genetic and histopathological analysis: a rare case report and literature review (2019) (0)
- Distinct DNA methylation targets by aging and chronic inflammation: a pilot study using gastric mucosa infected with Helicobacter pylori (2019) (0)
- Abstract LB-092: High impact of methylation accumulation on cancer risk: 5-year follow-up of a multicenter prospective cohort study (2017) (0)
- EPIGENETIC REGULATION OF BRCA1 IN ALZHEIMER’S DISEASE: EVALUATION OF POSTMORTEM BRAIN AND MODEL MICE REVEALS IMPORTANCE OF AGGREGATED TAU (2016) (0)
- P1.02-009 Accumulation of Mutations in Background Normal Lung Tissue Constitutes a Major Lung Cancer Risk (2017) (0)
- SARS-CoV-2 antibody response to symptoms indicative of COVID-19 in a non-infected population in Japan: A cross-sectional study. (2022) (0)
- Cdyl2 is a chromodomain protein involved in maintenance of pluripotency in embryonic stem cells (2015) (0)
- Abstract 6014: Cancer risk diagnosis by epimutation burden: a multicenter prospective study (2023) (0)
- Contents Vol. 88, 2015 (2015) (0)
- Abstract 141: Identification of a gene silenced in rat mammary carcinomas by combination of DNA methylation microarray and chemical genomic screening (2010) (0)
- In vivo mutagenicity of 2-amino-3,4-dimethylimidazol[4,5-f]quinoline in lac I transgenic mice (Big Blue®) (1996) (0)
- GC-01ELUCIDATION OF PATHOGENESIS IN INTRACRANIAL GERM CELL TUMORS BASED ON A GENOME-WIDE METHYLATION STUDY (2015) (0)
- Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells (2019) (0)
- WHOLE EXOME SEQUENCING IDENTIFIED THAT THE MAPK AND PI3K PATHWAYS ARE THE MAIN TARGETS FOR MUTATIONS IN INTRACRANIAL GERM CELL TUMORS. (2014) (0)
- [Involvement of proto-ret and activated ret in human malignancy]. (1991) (0)
- Epigenomic Analysis in Toxicology (2011) (0)
- [Familial breast cancer]. (1995) (0)
- Abstract #4749: Involvement of microRNA silencing in the formation of field defect for gastric carcinogenesis (2009) (0)
- Abstract 6024: Precancerous nature of intestinal metaplasia with accelerated DNA methylation along with altered epigenomic landscape (2023) (0)
- Involvement of metabolome-associated epigenetic modifications in Parkinson's disease (2022) (0)
- Multiple analyses of epigenetics modification in the spinal cord of sciatic nerve-ligated mice under neuropathic pain (2011) (0)
- Comprehensive molecular profiling of advanced gastric cancer (AGC) using NGS and immunohistochemistry (IHC). (2014) (0)
- Epigenetic impact of infection on carcinogenesis: mechanisms and applications (2016) (0)
- 7TH ANNUAL SCIENTIFIC MEETING (2014) (0)
- Abstract 4264: Whole exome and targeted sequencing identified the MAPK and PI3K pathways as the main targets in intracranial and testicular germ cell tumors (2014) (0)
- Dual inhibition of BET and mutant BRAF in BRAF-mutant colon cancer cells suppresses oncogenic pathways and synergistically inhibits their growth (2016) (0)
- Abstract 1048: Chromatin remodelers are frequently disrupted by epigenetic and genetic alterations at an early stage of carcinogenesis (2015) (0)
- Abstract LB-157: Demonstration of the usefulness of an epigenetic cancer risk marker by a multicenter prospective cohort study (2015) (0)
- Erratum: Epigenetic mechanisms of chronic pain [Trends in Neurosciences 38 (2015), 237-246] (2015) (0)
- Abstract 4089: Identification of a DNA methylation marker to detect the presence of lymph node metastases of gastric cancers (2012) (0)
- Aberrant Regional DNA Hypermethylation As a Preventive and Therapeutic Target for Adult T-Cell Leukemia-Lymphoma (2018) (0)
- Dual targeting of aberrant DNA and histone methylation synergistically suppresses tumor cell growth in ATL (2022) (0)
- Hypomethylation of Alu repetitive elements in esophageal mucosa, and its potential contribution to the epigenetic field for cancerization (2012) (0)
- Low-dose DNA demethylating therapy induces reprogramming of diverse cancer-related pathways at the single-cell level (2020) (0)
- GC-09GENOME-WIDE DNA METHYLATION AND TRANSCRIPTOMIC PROFILING IN PRIMARY CENTRAL NERVOUS SYSTEM GERM CELL TUMORS SUGGESTS A PRIMORDIAL GERM CELL ORIGIN FOR GERMINOMA. (2016) (0)
- [Acquired disorders and epigenetics]. (2010) (0)
- Development of the arbitrarily pi analysis method and chromosoma throughput rat genetic markers (2016) (0)
- Differential expression of genes related to levels of mucosal cell proliferation among multiple rat strains by using oligonucleotide microsarays (2004) (0)
- Future Perspective of DNA and Histone Methylation as Cancer Targets (2017) (0)
- Revisit of Field Cancerization in Squamous Cell Carcinoma of Upper Aerodigestive Tract: Better Risk Prediction With Epigenetic Markers (2011) (0)
- High-risk oral leukoplakia is associated with aberrant promoter methylation of multiple genes (2016) (0)
- Abstract 5375: Androgen excess induces aberrant DNA methylation in the prostate. (2013) (0)
- Abstract LB-284: Toward clinical sequencing: analysis of FFPE samples of 121 gastric cancer by a benchtop sequencer (2014) (0)
- Abstract 5349: Aberrant trimethylation of histone H3 lysine 27 is induced by chronic inflammation in mouse colonic epithelial cells, and is involved in the formation of a field for cancerization. (2013) (0)
- 717 Combined Exposure to Multiple Carcinogens Enhances Development of Rat Mammary Cancers With Characteristic Gene Expression (2012) (0)
- EPN-01MOLECULAR CLASSIFICATION OF EPENDYMOMAS IN A JAPANESE PEDIATRIC MOLECULAR NEURO-ONCOLOGY GROUP (JPMNG) SERIES (2016) (0)
- p53 mutations in MeIQ-induced mouse forestomach tumors. (1997) (0)
- Proto-oncogene Mutation Is Specific for the Neurofibromas in a N-Nitroso-N-ethylurea-induced Hamster Neurofibromatosis Model but not for Hamster Melanomas and Human Schwann Cell Tumors 1 (2007) (0)
- [Epigenome and human disease]. (2009) (0)
- Induction of CDH1 gene expression using the Platinum TALE- and CRISPR-Cas9-based next-generation transcriptional activation systems (2017) (0)
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What Schools Are Affiliated With Toshikazu Ushijima?
Toshikazu Ushijima is affiliated with the following schools:
