Toshimichi Ikemura

Toshimichi Ikemura's AcademicInfluence.com Rankings

Toshimichi Ikemura

Biology

#8006

World Rank

#11014

Historical Rank

Genetics

#782

World Rank

#874

Historical Rank

Molecular Biology

#975

World Rank

#999

Historical Rank

Biochemistry

#1139

World Rank

#1257

Historical Rank

biology Degrees

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Biology

Toshimichi Ikemura's Degrees

PhD Biochemistry University of Tokyo
Masters Biochemistry University of Tokyo
Bachelors Biochemistry University of Tokyo

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Toshimichi Ikemura's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Codon usage and tRNA content in unicellular and multicellular organisms. (1985) (1671)
Correlation between the abundance of Escherichia coli transfer RNAs and the occurrence of the respective codons in its protein genes: a proposal for a synonymous codon choice that is optimal for the E. coli translational system. (1981) (1239)
Codon usage tabulated from international DNA sequence databases: status for the year 2000 (2000) (1227)
Correlation between the abundance of Escherichia coli transfer RNAs and the occurrence of the respective codons in its protein genes. (1981) (867)
Correlation between the abundance of yeast transfer RNAs and the occurrence of the respective codons in protein genes. Differences in synonymous codon choice patterns of yeast and Escherichia coli with reference to the abundance of isoaccepting transfer RNAs. (1982) (569)
Rice Annotation Project Database (RAP-DB): An Integrative and Interactive Database for Rice Genomics (2013) (545)
Codon usage tabulated from the GenBank Genetic Sequence Data. (1988) (459)
Studies of codon usage and tRNA genes of 18 unicellular organisms and quantification of Bacillus subtilis tRNAs: gene expression level and species-specific diversity of codon usage based on multivariate analysis. (1999) (419)
Substrate-induced gene-expression screening of environmental metagenome libraries for isolation of catabolic genes (2005) (365)
Codon usage tabulated from the GenBank genetic sequence data. (1991) (309)
Codon Usage and tRNA Genes in Eukaryotes: Correlation of Codon Usage Diversity with Translation Efficiency and with CG-Dinucleotide Usage as Assessed by Multivariate Analysis (2001) (266)
Informatics for unveiling hidden genome signatures. (2003) (259)
Three genes in the human MHC class III region near the junction with the class II: gene for receptor of advanced glycosylation end products, PBX2 homeobox gene and a notch homolog, human counterpart of mouse mammary tumor gene int-3. (1994) (245)
Analysis of codon usage diversity of bacterial genes with a self-organizing map (SOM): characterization of horizontally transferred genes with emphasis on the E. coli O157 genome. (2001) (192)
Small ribonucleic acids of Escherichia coli. I. Characterization by polyacrylamide gel electrophoresis and fingerprint analysis. (1973) (190)
Codon usage tabulated from the international DNA sequence databases (1997) (188)
Diversity in G + C content at the third position of codons in vertebrate genes and its cause. (1986) (187)
Specific inactivation of 16S ribosomal RNA induced by colicin E3 in vivo. (1971) (185)
CENP‐H, a constitutive centromere component, is required for centromere targeting of CENP‐C in vertebrate cells (2001) (177)
Molecular dynamics of MHC genesis unraveled by sequence analysis of the 1,796,938-bp HLA class I region. (1999) (173)
Chromosomal localization of the proteasome Z subunit gene reveals an ancient chromosomal duplication involving the major histocompatibility complex. (1996) (170)
The distribution of tenascin-X is distinct and often reciprocal to that of tenascin-C (1994) (161)
Codon usage and transfer RNA contents: organism-specific codon-choice patterns in reference to the isoacceptor contents. (1983) (158)
CENP-I is essential for centromere function in vertebrate cells. (2002) (153)
Chromosome-wide assessment of replication timing for human chromosomes 11q and 21q: disease-related genes in timing-switch regions. (2002) (133)
8-oxoguanine causes spontaneous de novo germline mutations in mice (2014) (127)
Novel phylogenetic studies of genomic sequence fragments derived from uncultured microbe mixtures in environmental and clinical samples. (2005) (127)
Condon usage tabulated from the international DNA sequence databases (1996) (125)
Nucleotide sequence analysis of the HLA class I region spanning the 237-kb segment around the HLA-B and -C genes. (1997) (107)
Identification of spacer tRNA genes in individual ribosomal RNA transcription units of Escherichia coli. (1977) (100)
Codon usage tabulated from the international DNA sequence databases; its status 1999 (1999) (98)
Temperature sensitive mutants of Escherichia coli for tRNA synthesis. (1974) (97)
Global variation in G+C content along vertebrate genome DNA. Possible correlation with chromosome band structures. (1988) (96)
Expression of spacer tRNA genes in ribosomal RNA transcription units carried by hybrid col E1 plasmids in E. coli (1977) (96)
Precise switching of DNA replication timing in the GC content transition area in the human major histocompatibility complex (1997) (92)
Small ribonucleic acids of Escherichia coli. II. Noncoordinate accumulation during stringent control. (1973) (90)
Nucleotide sequencing analysis of the 146-kilobase segment around the IkBL and MICA genes at the centromeric end of the HLA class I region. (1998) (89)
tRNADB-CE 2011: tRNA gene database curated manually by experts (2010) (88)
Triplex-forming DNAs in the human interphase nucleus visualized in situ by polypurine/polypyrimidine DNA probes and antitriplex antibodies (2002) (86)
Evident diversity of codon usage patterns of human genes with respect to chromosome banding patterns and chromosome numbers; relation between nucleotide sequence data and cytogenetic data. (1991) (79)
A boundary of long-range G + C% mosaic domains in the human MHC locus: pseudoautosomal boundary-like sequence exists near the boundary. (1995) (79)
Cluster of fibronectin type III repeats found in the human major histocompatibility complex class III region shows the highest homology with the repeats in an extracellular matrix protein, tenascin. (1992) (77)
Some rRNA operons in E. coli have tRNA genes at their distal ends (1978) (73)
Proto‐oncogene of int‐3, a mouse Notch homologue, is expressed in endothelial cells during early embryogenesis (1997) (70)
Gross map location of Escherichia coli transfer RNA genes. (1977) (66)
Levels of tRNAs in bacterial cells as affected by amino acid usage in proteins. (1991) (63)
Creation and characterization of temperature-sensitive CENP-C mutants in vertebrate cells. (2001) (62)
Periodicity in prokaryotic and eukaryotic genomes identified by power spectrum analysis. (2002) (60)
Direct cloning of genes encoding novel xylanases from the human gut. (2005) (58)
A novel approach, based on BLSOMs (Batch Learning Self-Organizing Maps), to the microbiome analysis of ticks (2014) (55)
Codon usage tabulated from the international DNA sequence databases (1998) (55)
Giant G+C% mosaic structures of the human genome found by arrangement of GenBank human DNA sequences according to genetic positions. (1990) (54)
Structural analysis of mouse tenascin-X: evolutionary aspects of reduplication of FNIII repeats in the tenascin gene family. (1998) (53)
Precursor molecules of Escherichia coli transfer RNAs accumulated in a temperature-sensitive mutant. (1975) (53)
Self-Organizing Map (SOM) unveils and visualizes hidden sequence characteristics of a wide range of eukaryote genomes. (2006) (48)
A novel bioinformatic strategy for unveiling hidden genome signatures of eukaryotes: self-organizing map of oligonucleotide frequency. (2002) (45)
A novel approach, based on BLSOMs (Batch Learning Self-Organizing Maps), to the microbiome analysis of ticks (2013) (43)
cDNA cloning of the human homologues of the mouse Ke4 and Ke6 genes at the centromeric end of the human MHC region. (1996) (41)
Genomic anatomy of a premier major histocompatibility complex paralogous region on chromosome 1q21-q22. (2001) (40)
tRNADB-CE: tRNA gene database well-timed in the era of big sequence data (2014) (40)
Relative locations of the centromere and imprinted SNRPN gene within chromosome 15 territories during the cell cycle in HL60 cells. (2000) (37)
Tenascin-X expression in tumor cells and fibroblasts: glucocorticoids as negative regulators in fibroblasts. (1996) (36)
Dinucleosome DNA of human K562 cells: experimental and computational characterizations. (2003) (36)
Gene organization of human NOTCH4 and (CTG)n polymorphism in this human counterpart gene of mouse proto-oncogene Int3. (1997) (33)
tRNADB-CE: tRNA gene database curated manually by experts (2008) (33)
Detection of genes in Escherichia coli sequences determined by genome projects and prediction of protein production levels, based on multivariate diversity in codon usage (1996) (32)
Amplicons on human chromosome 11q are located in the early/late-switch regions of replication timing. (2004) (32)
Genetics of Nonsense Suppressor tRNAs in Escherichia coli (1980) (32)
Novel bioinformatics strategies for prediction of directional sequence changes in influenza virus genomes and for surveillance of potentially hazardous strains (2013) (31)
Codon usage tabulated from the GenBank genetic sequence data. (1992) (26)
Intranuclear arrangement of human chromosome 12 correlates to large-scale replication domains (2000) (26)
Human pseudoautosomal boundary-like sequences: expression and involvement in evolutionary formation of the present-day pseudoautosomal boundary of human sex chromosomes. (1996) (24)
Replication timing of the human X-inactivation center (XIC) region: correlation with chromosome bands. (2000) (24)
A novel bioinformatics tool for phylogenetic classification of genomic sequence fragments derived from mixed genomes of uncultured environmental microbes (2006) (23)
Relationships between replication timing and GC content of cancer-related genes on human chromosomes 11q and 21q. (2009) (23)
Cloning of a new kinesin-related gene located at the centromeric end of the human MHC region (2004) (20)
The relation between the strong binding of spermine to polynucleotides and the conformation of polynucleotides. (1969) (18)
Prediction of Directional Changes of Influenza A Virus Genome Sequences with Emphasis on Pandemic H1N1/09 as a Model Case (2011) (17)
Extracellular matrix protein tenascin-like gene found in human MHC class III region (2004) (17)
Codonusagetabulated fromtheGenBankgenetic sequence data (1991) (17)
Sequences from Almost All Prokaryotic, Eukaryotic, and Viral Genomes Available Could be Classified According to Genomes on a Large-Scale Self-Organizing Map Constructed with the Earth Simulator (2006) (17)
Systematization of the protein sequence diversity in enzymes related to secondary metabolic pathways in plants, in the context of big data biology inspired by the KNApSAcK motorcycle database. (2013) (17)
A Novel Bioinformatics Strategy for Function Prediction of Poorly-Characterized Protein Genes Obtained from Metagenome Analyses (2009) (16)
Directional and reoccurring sequence change in zoonotic RNA virus genomes visualized by time-series word count (2016) (15)
Gene Classification by Self-Organization Mapping of Codon Usage in Bacteria with Completely Sequenced Genome (1998) (15)
GeneLook: a novel ab initio gene identification system suitable for automated annotation of prokaryotic sequences. (2005) (15)
Intra-Species Diversity between Seven Bifidobacterium adolescentis Strains Identified by Genome-Wide Tiling Array Analysis (2009) (14)
Two-dimensional polyacrylamide-gel electrophoresis for purification of small RNAs specified by virulent coliphages T4, T5, T7 and BF23. (1975) (14)
A novel bioinformatics strategy for searching industrially useful genome resources from metagenomic sequence libraries. (2011) (13)
Notable clustering of transcription-factor-binding motifs in human pericentric regions and its biological significance (2013) (13)
tRNA Genes in rRNA Operons of Escherichia coli (1980) (12)
Temperature-sensitive mutants of Escherichia coli defective in tRNA biosynthesis. (1975) (12)
Time-series analyses of directional sequence changes in SARS-CoV-2 genomes and an efficient search method for candidates for advantageous mutations for growth in human cells (2020) (12)
Replication timing of extremely large genes on human chromosomes 11q and 21q. (2008) (11)
Detection of periodicity in eukaryotic genomes on the basis of power spectrum analysis. (2002) (11)
Detection of tRNA Based on the Cloverleaf Secondary Structure (2000) (10)
Isolation and characterization of stable hybrid mRNA molecules transcribed from ribosomal protein promoters in E. coli (1979) (10)
A Novel Bioinformatics Strategy to Analyze Microbial Big Sequence Data for Efficient Knowledge Discovery: Batch-Learning Self-Organizing Map (BLSOM) (2013) (10)
Ultraviolet inactivation of the functions of phenylalanine and lysine transfer RNA's of Escherichia coli. (1969) (10)
Gene Classification Method Based on Batch-Learning SOM (1999) (9)
Time-series analyses of directional sequence changes in SARS-CoV-2 genomes and an efficient search method for candidates for advantageous mutations for growth in human cells. (2020) (9)
Systematization of Species-Specific Diversity of Genes in Codon Usage:Comparison of the Diversity Among Bacteria and Prediction of the Protein Production Levels in Cells (1996) (8)
Gene structure, chromosomal localization and immunolocalization of chicken centromere proteins CENP-C and ZW10. (2001) (8)
Nucleotide sequence and molecular evolution of mouse retrovirus-like IAP elements. (1987) (8)
Purification of RNA molecules by gel techniques. (1989) (8)
Triplet repeat polymorphism in the NOTCH4 gene with the human major histocompatibility complex in a healthy population and patients with a salivary gland tumor in Japan. (1997) (7)
Novel bioinformatics for inter- and intraspecies comparison of genome signatures in plant genomes (2009) (7)
Human cell-dependent, directional, time-dependent changes in the mono- and oligonucleotide compositions of SARS-CoV-2 genomes (2021) (7)
Codon usage tabulated from the GenBank genetic sequence data. (1990) (7)
Triplet repeat polymorphism within the NOTCH4 gene located near the junction of the HLA class II and class III regions in narcolepsy. (1997) (7)
Non-B DNA structures spatially and sequence-specifically associated with individual centromeres in the human interphase nucleus (2000) (7)
Mb-level CpG and TFBS islands visualized by AI and their roles in the nuclear organization of the human genome. (2020) (6)
Comparative genomics of Glandirana rugosa using unsupervised AI reveals a high CG frequency (2021) (6)
Clustering of transfer RNA genes in bacteriophage BF23. (1978) (6)
Correlation Between Codon Usage and tRNA Content in Microorganisms (2018) (5)
Development of Self-Compressing BLSOM for Comprehensive Analysis of Big Sequence Data (2015) (5)
Time-series oligonucleotide count to assign antiviral siRNAs with long utility fit in the big data era (2017) (5)
Small Ribonucleic Acids of, Escherichia coli (2002) (5)
Codon usage tabulated from the GenBank genetic sequence data. (1986) (5)
CG-containing oligonucleotides and transcription factor-binding motifs are enriched in human pericentric regions. (2015) (5)
Identification ofspacer tRNAgenesinindividual ribosomal RNA transcription units ofEscherichia coli (tRNAAla/tRNAAsP/ColE1 hybrid plasmids/X transducing phages/RNA'DNA hybridization) (1977) (5)
Polyadenylic acid-directed binding of oligolysyl transfer RNA to ribosomes. Inhibition by lysyl and deacylated transfer RNA. (1969) (5)
Evolutionary Changes in Vertebrate Genome Signatures with Special Focus on Coelacanth (2014) (5)
Statistical Analysis of Genomic Information (2000) (5)
Distribution of polypurine/polypyrimidine tract sequences in the human MHC region and their possible functions (2000) (5)
Quick Learning for Batch-Learning Self-Organizing Map (2002) (4)
Replication timing in a single human chromosome 11 transferred into the Chinese hamster ovary (CHO) cell line. (2012) (4)
Visualization of Genome Signatures of Eukaryote Genomes by Batch-Learning Self-Organizing Map with a Special Emphasis on Drosophila Genomes (2014) (4)
Implication of a new function of human tDNAs in chromatin organization (2020) (4)
Recombination in the class III region of the mouse major histocompatibility complex (2004) (3)
Time-series trend of pandemic SARS-CoV-2 variants visualized using batch-learning self-organizing map for oligonucleotide compositions (2021) (3)
Unsupervised explainable AI for the collective analysis of a massive number of genome sequences: various examples from the small genome of pandemic SARS-CoV-2 to the human genome (2021) (3)
Batch-Learning Self-Organizing Map for Predicting Functions of Poorly-Characterized Proteins Massively Accumulated (2009) (3)
Unsupervised explainable AI for molecular evolutionary study of forty thousand SARS-CoV-2 genomes (2020) (3)
An artificial intelligence approach fit for tRNA gene studies in the era of big sequence data. (2017) (3)
Unsupervised explainable AI for simultaneous molecular evolutionary study of forty thousand SARS-CoV-2 genomes (2020) (2)
A Novel Bioinformatics Method for Efficient Knowledge Discovery by BLSOM from Big Genomic Sequence Data (2014) (2)
Cloning, sequencing and evolutionary analyses of the human major histocompatibility complex (MHC) region. (1996) (2)
Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (2021) (2)
The tRNA levels in bacterial cells as affected by amino acid usage in proteins. (1989) (2)
Role of glucocorticoid receptor in the regulation of cellular sensitivity to irinotecan hydrochloride. (2009) (2)
A Novel Bioinformatics Strategy to Predict Directional Changes of Influenza A Virus Genome Sequences (2011) (2)
Human cell-dependent, directional, time-dependent changes in the mono- and oligonucleotide compositions of SARS-CoV-2 genomes (2021) (2)
Statistical Analysis of Genomic Information: Various Periodicities in DNA Sequence (2001) (2)
[Measurement of relative amount of E. coli tRNAs: codon choice in E. coli genes is largely constrained by the concentration of anticodons (author's transl)]. (1980) (2)
Fop (frequency of optimal codon usage): WWW service with its distribution analysis (1995) (2)
Estimation of protein-production levels for ORFs found by E. coli and yeast genome projects, basing on levels of "optimal codon" usage, in connection with feasibility of their protein coding ability and with assignment to foreign-type genes (1994) (1)
Estimation of Protein-production levels in Escherichia coli Genes on the basis of Multivariate Diversity in Codon Usage (1995) (1)
Relationship between Gene Function and Codon Usage in Escherichia coli on the basis of Principal Component Analysis (1994) (1)
AI-based search for convergently expanding, advantageous mutations in SARS-CoV-2 by focusing on oligonucleotide frequencies (2022) (1)
Comparative Genome Analysis Focused on Periodicity from Prokaryote to Higher Eukaryote Genomes Based on Power Spectrum (2003) (1)
A Large-Scale Genomics Studies Conducted with Batch-Learning SOM Utilizing High-Performance Supercomputers (2009) (1)
Preliminary evaluation of batch-learning self-organizing map algorithm on a graphic processor (2010) (1)
Time-series analyses of directional sequence changes in SARS-CoV-2 genomes and an efficient search method for advantageous mutations for growth in human cells (2020) (1)
Characterization of Genetic Signal Sequences with Batch- Learning SOM (2007) (1)
A Large-scale Batch-learning Self-organizing Map for Function Prediction of Poorly-characterized Proteins Progressively Accumulating in Sequence Databases : Annual Report of the Earth Simulator Center April 2007-March 2008 (2007) (1)
Comparative genomic analysis of the human genome and six bat genomes using unsupervised machine learning: Mb-level CpG and TFBS islands (2022) (0)
Development Based on BLSOM for Unveiling Microbial Diversities Hidden in a Massive Number of Metagenomic Sequences (2015) (0)
Unsupervised explainable AI for molecular evolutionary study of forty thousand SARS-CoV-2 genomes (2022) (0)
Heterogeneity of synonymous substitution rates in the Xenopus frog genome (2020) (0)
P364 - Polymorphism of the CTG repeast and INT3 gene between the HLA class II and class III regions (1996) (0)
Sequences from Prokaryotic, Eukaryotic, and Viral Genomes Available Clustered According to Phylotype on a Self‐Organizing Map (2010) (0)
A fungus derived from a decayed timber secreted cellulose: identification of species and isolation of the cellulase (2016) (0)
Possibility of involvement of SINEs in differentiation: Formation of higher order structures of chromatin complexed with multiple transcription factors anchored by SINE during differentiation (2017) (0)
cDNA cloning, northern hybridization, and mapping analysis of a putative GDS-related protein gene at the centromeric ends of the human and mouse MHC regions (1999) (0)
Comparative genomic analysis of the human genome and six bat genomes using unsupervised machine learning: Mb-level CpG and TFBS islands (2022) (0)
[Replication timing during S phase and GC% distribution of human genome: disease-related genes found in transition regions of replication timing]. (2001) (0)
A Large-scale Genomics and Proteomics Analyses Conducted by the Earth Simulator (2009) (0)
[Tow-dimensional polyacrylamide gel electrophoresis of RNA species (author's transl)]. (1973) (0)
Assessment of Species-specific Diversity of Genes in Codon Usage (1995) (0)
A bioinformatics tool for phylogenetic classification of metagenomic sequences on the basis of SC-BLSOM (Self-Compressing BLSOM) (2016) (0)
Characteristics of transcription factor complex anchored by TFIIIC at tDNA and ETC locus (2017) (0)
A study of de novo germline mutation due to oxidative DNA damage (II) (2013) (0)
Prediction of directional changes of influenza virus genome sequences using by a novel bioinformatics strategy (2011) (0)
Genome Visualization by Isometric Projection Focused on Replication Origins and Termini, and Genome Instability (2002) (0)
[Triplex DNA in human interphase nuclei and its function]. (1999) (0)
Two-dimensional display of lambda and Escherichia coli restriction fragments separated by Hg-Cs2SO4 centrifugation and gel electrophoresis. (1981) (0)
[Biological significance of human chromosome bands]. (1996) (0)
Isolation of new replication factors by genetic screenings in budding yeast and their characterization: approach to elucidation of molecular mechanism in the initiation of eukaryotic DNA replication (2010) (0)
Oligonucleotide usage in coronavirus genomes mimics that in exon regions in host genomes (2023) (0)
DNA REPLICATION TIMING ON THE BOUNDARY OF HUMAN LONGRANGE G+C% MOSAIC DOMAIN (1995) (0)
Compartmentalization of the human Genome (1992) (0)
Codon usage pattern of vertebrates genes and chromosome banding pattern. (1987) (0)
A sensitive and efficient homology search method to find proteincoding regions using "protein-coding region DNA database" (1993) (0)
[Chromosome banding patterns of higher vertebrates and nucleotide sequences of their genes]. (1987) (0)
Procede et systeme de classification tres precise d'une grande quantite d'informations decrites avec des multivariables (2000) (0)
CHARACTERIZATION OF HUMAN PSEUDOAUTOSOMAL BOUNDARY-LIKE SEQUENCES (PABLS) FOUND NEAR THE BOUNDARY OF LONG-RANGE G+C% MOSAIC DOMAINS IN THE HUMAN GENOME (1995) (0)
[Evolution at levels of DNA and chromosomal bands]. (1994) (0)
Two-dimensional gel electrophoresis to separate large RNA molecules such as messenger RNAs. (1988) (0)
ANALYSIS FOR GIANT GC CONTENT MOSAIC DOMAINS AND ITS BOUNDARIES IN THE HUMAN GENOME (1995) (0)
Codon-Database and Intron-Database; Discriminant Analysis to assign protein-coding regions using the Databases (1991) (0)
Analysis of a tRNA gene-like sequence (t-element) with TTA at the anticodon position in the mitochondrial DNA ofDictyostelium discoideum (1996) (0)
Comparative genomics of the human genome and six bat genomes using AI: Mb-level CpG and TFBS islands (2022) (0)
[Education of life science database managers]. (2008) (0)
Gene organization of the MHC dass I region in human and Japanese quail (1996) (0)
A strategy for predicting gene functions from genome and metagenome sequences on the basis of oligopeptide frequency distance. (2020) (0)
Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (2022) (0)
SOM (Self-Organization Map) analyses of oligonucleotide frequencies reveal species- specific characteristics of eukaryotic genome sequences. (2007) (0)
Cloning of new expressed genes located at centromeric end of the HLA-DP subregion (1996) (0)
Unsupervised explainable artificial intelligence for molecular evolutionary studies of over forty thousand SARS-CoV-2 genomes (2020) (0)
Small RNA species of unknow functions in E. coli (1973) (0)
Notable clustering of transcription-factor-binding motifs in human pericentric regions and its biological significance (2013) (0)

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Published Works

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Toshimichi Ikemura's AcademicInfluence.com Rankings