Toshio Ogihara

Q: What Schools Are Affiliated With Toshio Ogihara

Toshio Ogihara is affiliated with the following schools: Morinomiya University of Medical Sciences, Ehime University, Osaka University, Kyoto University

Toshio Ogihara's AcademicInfluence.com Rankings

Toshio Ogihara

Computer Science

#3476

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#3648

Historical Rank

Data Mining

#39

World Rank

#39

Historical Rank

Machine Learning

#416

World Rank

#422

Historical Rank

Artificial Intelligence

#613

World Rank

#624

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Computer Science

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Toshio Ogihara's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Genetic Variants in Novel Pathways Influence Blood Pressure and Cardiovascular Disease Risk (2011) (1928)
The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2009) (2009) (1116)
In vivo transfection of cis element “decoy” against nuclear factor- κB binding site prevents myocardial infarction (1997) (637)
Hypoadiponectinemia Is an Independent Risk Factor for Hypertension (2004) (597)
Association of Hypoadiponectinemia With Impaired Vasoreactivity (2003) (592)
Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians (2011) (534)
Serum Uric Acid and Plasma Norepinephrine Concentrations Predict Subsequent Weight Gain and Blood Pressure Elevation (2003) (515)
A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo. (1995) (481)
Single intraluminal delivery of antisense cdc2 kinase and proliferating-cell nuclear antigen oligonucleotides results in chronic inhibition of neointimal hyperplasia. (1993) (454)
Novel Autologous Cell Therapy in Ischemic Limb Disease Through Growth Factor Secretion by Cultured Adipose Tissue-derived Stromal Cells: P198 (2005) (412)
Development of safe and efficient novel nonviral gene transfer using ultrasound: enhancement of transfection efficiency of naked plasmid DNA in skeletal muscle (2002) (411)
Local Delivery of Plasmid DNA Into Rat Carotid Artery Using Ultrasound (2002) (385)
Adipose tissue-derived stromal cells as a novel option for regenerative cell therapy. (2006) (376)
The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2009)—Chapter 2 (2009) (365)
Target Blood Pressure for Treatment of Isolated Systolic Hypertension in the Elderly: Valsartan in Elderly Isolated Systolic Hypertension Study (2010) (326)
Intimal hyperplasia after vascular injury is inhibited by antisense cdk 2 kinase oligonucleotides. (1994) (305)
Deletion of Angiotensin-Converting Enzyme 2 Accelerates Pressure Overload–Induced Cardiac Dysfunction by Increasing Local Angiotensin II (2006) (299)
Enhancement of insulin sensitivity by troglitazone lowers blood pressure in diabetic hypertensives. (1995) (285)
Therapeutic angiogenesis induced by human recombinant hepatocyte growth factor in rabbit hind limb ischemia model as cytokine supplement therapy. (1999) (272)
Meta-analysis identifies multiple loci associated with kidney function–related traits in east Asian populations (2012) (264)
Angiotensin II accelerates osteoporosis by activating osteoclasts (2008) (251)
Pancreatic β Cell–specific Expression of Thioredoxin, an Antioxidative and Antiapoptotic Protein, Prevents Autoimmune and Streptozotocin-induced Diabetes (1998) (249)
Association between a deletion polymorphism of the angiotensin-converting-enzyme gene and left ventricular hypertrophy. (1994) (245)
Meta-analysis of association of insertion/deletion polymorphism of angiotensin I-converting enzyme gene with diabetic nephropathy and retinopathy (1998) (241)
Endothelial Apoptosis Induced by Oxidative Stress Through Activation of NF-&kgr;B: Antiapoptotic Effect of Antioxidant Agents on Endothelial Cells (2001) (234)
Effects of Candesartan Compared With Amlodipine in Hypertensive Patients With High Cardiovascular Risks: Candesartan Antihypertensive Survival Evaluation in Japan Trial (2008) (234)
Angiogenesis induced by hepatocyte growth factor in non-infarcted myocardium and infarcted myocardium: up-regulation of essential transcription factor for angiogenesis, ets (2000) (231)
Effect of two alpha-glucosidase inhibitors, voglibose and acarbose, on postprandial hyperglycemia correlates with subjective abdominal symptoms. (2005) (227)
Therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat and rabbit hindlimb ischemia models: preclinical study for treatment of peripheral arterial disease (2001) (226)
Deletion allele of angiotensin-converting enzyme gene increases risk of essential hypertension in Japanese men : the Suita Study. (2000) (223)
Evidence for endothelin-1 release from resistance vessels of rats in response to hypoxia. (1990) (219)
Safety Evaluation of Clinical Gene Therapy Using Hepatocyte Growth Factor to Treat Peripheral Arterial Disease (2004) (219)
Upregulation of renin-angiotensin system during differentiation of monocytes to macrophages. (1999) (218)
Evidence for direct local effect of angiotensin in vascular hypertrophy. In vivo gene transfer of angiotensin converting enzyme. (1994) (217)
Anti-apoptotic and anti-senescence effects of Klotho on vascular endothelial cells. (2006) (206)
Blood Pressure and Hypertension Are Associated With 7 Loci in the Japanese Population (2010) (204)
Application of transcription factor "decoy" strategy as means of gene therapy and study of gene expression in cardiovascular disease. (1998) (203)
The Japanese Society of Hypertension Committee for Guidelines for the Management of Hypertension (2009) (199)
Hepatocyte growth factor is a novel member of the endothelium-specific growth factors: additive stimulatory effect of hepatocyte growth factor with basic fibroblast growth factor but not with vascular endothelial growth factor (1996) (198)
Nitric oxide induces upregulation of Fas and apoptosis in vascular smooth muscle. (1996) (198)
A non-chromatographic non-extraction radioimmunoassay for serum aldosterone. (1977) (189)
Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study (2011) (185)
Potential contribution of a novel antifibrotic factor, hepatocyte growth factor, to prevention of myocardial fibrosis by angiotensin II blockade in cardiomyopathic hamsters. (2000) (184)
Sympathetic nerve hyperactivity precedes hyperinsulinemia and blood pressure elevation in a young, nonobese Japanese population. (1997) (183)
Pharmacological blood pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure: an individual participant-level data meta-analysis (2021) (181)
Asian-specific HLA haplotypes reveal heterogeneity of the contribution of HLA-DR and -DQ haplotypes to susceptibility to type 1 diabetes. (2002) (177)
Randomized, double-blind, placebo-controlled clinical trial of hepatocyte growth factor plasmid for critical limb ischemia (2010) (172)
Rationale, study design and implementation of the COLM study: the combination of OLMesartan and calcium channel blocker or diuretic in high-risk elderly hypertensive patients (2009) (171)
Therapeutic Angiogenesis Induced by Human Hepatocyte Growth Factor Gene in Rat Diabetic Hind Limb Ischemia Model: Molecular Mechanisms of Delayed Angiogenesis in Diabetes (2001) (171)
The seasonal variation of blood pressure in patients with essential hypertension. (1982) (170)
Phosphorylation of p38 mitogen-activated protein kinase downstream of bax-caspase-3 pathway leads to cell death induced by high D-glucose in human endothelial cells. (2001) (168)
Hypoxia-Induced Endothelial Apoptosis Through Nuclear Factor-κB (NF-κB)–Mediated bcl-2 Suppression In Vivo Evidence of the Importance of NF-κB in Endothelial Cell Regulation (2000) (167)
Adiponectin I164T mutation is associated with the metabolic syndrome and coronary artery disease. (2004) (166)
Endothelin inhibits renin release from isolated rat glomeruli. (1988) (164)
[Bartter syndrome]. (2020) (163)
Prevention and Treatment of Obesity, Insulin Resistance, and Diabetes by Bile Acid–Binding Resin (2007) (163)
Salt sensitivity of Japanese from the viewpoint of gene polymorphism. (2003) (158)
Weight gain-induced blood pressure elevation. (2000) (158)
A potent genetic risk factor for restenosis (1993) (157)
Pharmacokinetics of antisense oligodeoxyribonucleotides (cyclin B1 and CDC 2 kinase) in the vessel wall in vivo: enhanced therapeutic utility for restenosis by HVJ-liposome delivery. (1994) (155)
Mitogenic and Antiapoptotic Actions of Hepatocyte Growth Factor Through ERK, STAT3, and Akt in Endothelial Cells (2001) (153)
Telmisartan But Not Valsartan Increases Caloric Expenditure and Protects Against Weight Gain and Hepatic Steatosis (2006) (152)
Angiogenesis Induced by Endothelial Nitric Oxide Synthase Gene Through Vascular Endothelial Growth Factor Expression in a Rat Hindlimb Ischemia Model (2003) (150)
Angiotensin Receptor Blocker Prevented &bgr;-Amyloid–Induced Cognitive Impairment Associated With Recovery of Neurovascular Coupling (2009) (150)
Apoptosis Signal-Regulating Kinase 1 Mediates Cellular Senescence Induced by High Glucose in Endothelial Cells (2006) (150)
Meta-Analysis of the Association of Trp64Arg Polymorphism ofβ3-Adrenergic Receptor Gene with Body Mass Index1 (1998) (150)
Genome-wide association study of coronary artery disease in the Japanese (2011) (147)
Association of Hypoadiponectinemia With Smoking Habit in Men (2005) (145)
Association analysis of a polymorphism of the angiotensin converting enzyme gene with essential hypertension in the Japanese population. (1993) (144)
Endothelin enhances adrenergic vasoconstriction in perfused rat mesenteric arteries. (1989) (138)
Impaired endothelial function with essential hypertension assessed by ultrasonography. (1996) (135)
Potential role of hepatocyte growth factor, a novel angiogenic growth factor, in peripheral arterial disease: downregulation of HGF in response to hypoxia in vascular cells. (1999) (134)
The 717Val----Ile substitution in amyloid precursor protein is associated with familial Alzheimer's disease regardless of ethnic groups. (1991) (132)
The Japanese Trial to Assess Optimal Systolic Blood Pressure in Elderly Hypertensive Patients (JATOS): Protocol, Patient Characteristics, and Blood Pressure during the First 12 Months (2005) (131)
Angiotensin II type 1 receptor gene polymorphism is associated with increase of left ventricular mass but not with hypertension. (1998) (130)
Potential Role of an Endothelium-Specific Growth Factor, Hepatocyte Growth Factor, on Endothelial Damage in Diabetes (1997) (129)
Angiogenesis and Antifibrotic Action by Hepatocyte Growth Factor in Cardiomyopathy (2002) (127)
Confirmation of ALDH2 as a Major locus of drinking behavior and of its variants regulating multiple metabolic phenotypes in a Japanese population. (2011) (126)
Quantitative ultrasonic tissue characterization can identify high-risk atherosclerotic alteration in human carotid arteries. (2000) (124)
Endothelin-1 Gene Variant Associates With Blood Pressure in Obese Japanese Subjects: The Ohasama Study (2001) (124)
Association analysis of a polymorphism of the angiotensinogen gene with essential hypertension in Japanese. (1994) (124)
Green coffee bean extract improves human vasoreactivity. (2004) (123)
Nitric oxide mediates interleukin-1-induced prostaglandin E2 production by vascular smooth muscle cells. (1993) (123)
Inhibition of intimal hyperplasia after balloon injury in rat carotid artery model using cis-element ‘decoy’ of nuclear factor-kB binding site as a novel molecular strategy (2001) (123)
Transient decrease in high blood pressure by in vivo transfer of antisense oligodeoxynucleotides against rat angiotensinogen. (1995) (121)
An efficient gene transfer method mediated by ultrasound and microbubbles into the kidney (2005) (120)
Uric Acid, Left Ventricular Mass Index, and Risk of Cardiovascular Disease in Essential Hypertension (2006) (120)
Prevention of graft coronary arteriosclerosis by antisense cdk2 kinase oligonucleotide (1997) (119)
A vascular modulator, hepatocyte growth factor, is associated with systolic pressure. (1996) (117)
Intratumoral injection of oligonucleotides to the NFκB binding site inhibits cachexia in a mouse tumor model (1999) (116)
Nitric oxide mediates cytotoxicity and basic fibroblast growth factor release in cultured vascular smooth muscle cells. A possible mechanism of neovascularization in atherosclerotic plaques. (1995) (116)
Cyclic AMP inhibited proliferation of human aortic vascular smooth muscle cells, accompanied by induction of p53 and p21. (2000) (115)
Phase I/IIa Clinical Trial of Therapeutic Angiogenesis Using Hepatocyte Growth Factor Gene Transfer to Treat Critical Limb Ischemia (2011) (115)
Hydrogen peroxide induces up-regulation of Fas in human endothelial cells. (1998) (114)
In vivo administration of a nuclear transcription factor-kappaB decoy suppresses experimental crescentic glomerulonephritis. (2000) (113)
Azelnidipine and amlodipine: a comparison of their pharmacokinetics and effects on ambulatory blood pressure. (2003) (113)
Converting enzyme inhibitor improves forearm reactive hyperemia in essential hypertension. (1997) (113)
β2- and β3-Adrenergic Receptor Polymorphisms Are Related to the Onset of Weight Gain and Blood Pressure Elevation Over 5 Years (2005) (113)
Endothelial dysfunction in hyperglycemia as a trigger of atherosclerosis. (2005) (113)
Direct in vivo gene introduction into rat kidney. (1992) (111)
Periostin as a Novel Factor Responsible for Ventricular Dilation (2004) (111)
Prevention and regression of atopic dermatitis by ointment containing NF-kB decoy oligodeoxynucleotides in NC/Nga atopic mouse model (2002) (110)
Therapeutic angiogenesis using hepatocyte growth factor (HGF). (2004) (109)
Converting enzyme inhibitors regressed cardiac hypertrophy and reduced tissue angiotensin II in spontaneously hypertensive rats. (1991) (109)
Adiponectin and renal function, and implication as a risk of cardiovascular disease. (2006) (108)
Identification of a new susceptibility locus for insulin-dependent diabetes mellitus by ancestral haplotype congenic mapping. (1995) (107)
In Vivo Evidence of Angiogenesis Induced by Transcription Factor Ets-1: Ets-1 Is Located Upstream of Angiogenesis Cascade (2004) (106)
Homozygous and compound heterozygous mutations at the Werner syndrome locus. (1996) (106)
Angiotensin I-Converting Enzyme Gene Polymorphism Is Associated With Myocardial Infarction, but Not With Retinopathy or Nephropathy, in NIDDM (1995) (106)
Association of a polymorphic variant of the Werner helicase gene with myocardial infarction in a Japanese population. (1997) (105)
Common Variants in the ATP2B1 Gene Are Associated With Susceptibility to Hypertension: The Japanese Millennium Genome Project (2010) (105)
Gene Transfer of Human Prostacyclin Synthase Ameliorates Monocrotaline-Induced Pulmonary Hypertension in Rats (2000) (104)
Novel Therapeutic Strategy to Treat Brain Ischemia: Overexpression of Hepatocyte Growth Factor Gene Reduced Ischemic Injury Without Cerebral Edema in Rat Model (2004) (104)
Ribozyme Oligonucleotides Against Transforming Growth Factor-&bgr; Inhibited Neointimal Formation After Vascular Injury in Rat Model: Potential Application of Ribozyme Strategy to Treat Cardiovascular Disease (2000) (104)
Novel and effective gene transfer technique for study of vascular renin angiotensin system. (1993) (103)
The renin-angiotensin and adrenergic nervous system in cardiac hypertrophy in fructose-fed rats. (2002) (103)
Weight reduction and pharmacologic treatment in obese hypertensives. (2001) (102)
Angiotensin II type 1 receptor-mediated peroxide production in human macrophages. (1999) (101)
Enhanced expression of angiotensin‐converting enzyme is associated with progression of coronary atherosclerosis in humans (1997) (101)
Development of efficient plasmid DNA transfer into adult rat central nervous system using microbubble-enhanced ultrasound (2004) (99)
Matrix extracellular phosphoglycoprotein (MEPE) is highly expressed in osteocytes in human bone (2003) (98)
Measurement of plasma renin activity by a simple solid phase radioimmunoassay. (1982) (98)
Possible role of the vascular renin-angiotensin system in hypertension and vascular hypertrophy. (1992) (98)
Inhibition of Experimental Abdominal Aortic Aneurysm in the Rat by Use of Decoy Oligodeoxynucleotides Suppressing Activity of Nuclear Factor &kgr;B and ets Transcription Factors (2003) (98)
Anti-oxidative effect of Klotho on endothelial cells through cAMP activation (2007) (97)
β-cell neogenesis induced by adenovirus-mediated gene delivery of transcription factor pdx-1 into mouse pancreas (2003) (96)
Endothelin stimulates aldosterone biosynthesis by dispersed rabbit adreno-capsular cells. (1989) (96)
Angiogenic Property of Hepatocyte Growth Factor Is Dependent on Upregulation of Essential Transcription Factor for Angiogenesis, ets-1 (2003) (95)
Molecular cloning and expression of cDNAs encoding rat aldosterone synthase: Variants of cytochrome P-45011β (1990) (95)
Inhibition of development of experimental aortic abdominal aneurysm in rat model by atorvastatin through inhibition of macrophage migration. (2009) (95)
Prevention of cardiovascular events with calcium channel blocker-based combination therapies in patients with hypertension: a randomized controlled trial (2011) (95)
Polymorphism of angiotensin converting enzyme, angiotensinogen, and apolipoprotein E genes in a Japanese population with cerebrovascular disease. (1997) (95)
Potential role of hepatocyte growth factor in the maintenance of renal structure: anti-apoptotic action of HGF on epithelial cells. (1998) (94)
Apolipoprotein E4 Stimulates cAMP Response Element-binding Protein Transcriptional Activity through the Extracellular Signal-regulated Kinase Pathway* (2001) (94)
Hypoxia-induced endothelial apoptosis through nuclear factor-kappaB (NF-kappaB)-mediated bcl-2 suppression: in vivo evidence of the importance of NF-kappaB in endothelial cell regulation. (2000) (94)
Concentration-Dependent Mode of Interaction of Angiotensin II Receptor Blockers with Uric Acid Transporter (2007) (93)
Snail, a transcriptional regulator, represses nephrin expression in glomerular epithelial cells of nephrotic rats (2007) (93)
The association of CTLA4 polymorphism with type 1 diabetes is concentrated in patients complicated with autoimmune thyroid disease: a multicenter collaborative study in Japan. (2006) (93)
Methylenetetrahydrofolate reductase gene polymorphism: relation to blood pressure and cerebrovascular disease. (1998) (93)
Homocysteine Enhances Endothelial Apoptosis via Upregulation of Fas-Mediated Pathways (2004) (91)
The aldehyde dehydrogenase 2 gene is a risk factor for hypertension in Japanese but does not alter the sensitivity to pressor effects of alcohol: the Suita study. (2001) (91)
Transfection of NFκB-decoy oligodeoxynucleotides using efficient ultrasound-mediated gene transfer into donor kidneys prolonged survival of rat renal allografts (2003) (90)
Negative regulation of local hepatocyte growth factor expression by angiotensin II and transforming growth factor-beta in blood vessels: potential role of HGF in cardiovascular disease. (1998) (90)
Gene polymorphism of the renin-angiotensin system associates with risk for lacunar infarction. The Ohasama study. (2000) (90)
Endothelin inhibits presynaptic adrenergic neurotransmission in rat mesenteric artery. (1989) (90)
Human G-protein beta3 subunit variant is associated with serum potassium and total cholesterol levels but not with blood pressure. (2000) (90)
Comparison of the myotonic dystrophy associated CTG repeat in European and Japanese populations. (1992) (90)
The role of sympathetic nervous activity in renal injury and end-stage renal disease (2010) (90)
Transcription factor decoy for NFκB inhibits TNF-α-induced cytokine and adhesion molecule expression in vivo (2000) (89)
Comparison of Arterial Functional Evaluations as a Predictor of Cardiovascular Events in Hypertensive Patients: The Non-Invasive Atherosclerotic Evaluation in Hypertension (NOAH) Study (2008) (88)
Molecular therapy to inhibit NFkappaB activation by transcription factor decoy oligonucleotides. (2004) (88)
Detection of embolic particles with the Doppler guide wire during coronary intervention in patients with acute myocardial infarction: efficacy of distal protection device. (2005) (87)
Association of Methylenetetrahydrofolate Reductase Gene Polymorphism With Carotid Atherosclerosis Depending on Smoking Status in a Japanese General Population (2003) (85)
In vivo transfer of human hepatocyte growth factor gene accelerates re-endothelialization and inhibits neointimal formation after balloon injury in rat model (2000) (85)
Endothelin stimulates the release of prostacyclin from rat mesenteric arteries. (1989) (85)
Impairment of Collateral Formation in Lipoprotein(a) Transgenic Mice: Therapeutic Angiogenesis Induced by Human Hepatocyte Growth Factor Gene (2002) (85)
Reduction of risk of pneumonia associated with use of angiotensin I converting enzyme inhibitors in elderly inpatients. (1999) (85)
Lack of association between genetic polymorphism of CYP11B2 and hypertension in Japanese: the Suita Study. (2001) (85)
Interleukin-6 stimulates c-myc expression and proliferation of cultured vascular smooth muscle cells. (1990) (84)
Role of hepatocyte growth factor in endothelial regulation: prevention of high D-glucose-induced endothelial cell death by prostaglandins and phosphodiesterase type 3 inhibitor (1997) (83)
A common polymorphism of uncoupling protein 2 gene is associated with hypertension (2004) (82)
Autocrine-paracrine effects of overexpression of hepatocyte growth factor gene on growth of endothelial cells. (1996) (82)
Cardiovascular and renal complications of type 2 diabetes in obesity: role of sympathetic nerve activity and insulin resistance. (2010) (82)
Captopril inhibits endothelin-1 secretion from endothelial cells through bradykinin. (1993) (82)
Contribution of Bcl-2, but Not Bcl-xL and Bax, to Antiapoptotic Actions of Hepatocyte Growth Factor in Hypoxia-Conditioned Human Endothelial Cells (2001) (81)
Plasma asymmetric dimethylarginine and coronary and peripheral endothelial dysfunction in hypertensive patients. (2004) (80)
LMNA mutation in a 45 year old Japanese subject with Hutchinson-Gilford progeria syndrome (2004) (80)
The NSY mouse: a new animal model of spontaneous NIDDM with moderate obesity (1995) (80)
Genetic analysis of late-onset type 2 diabetes in a mouse model of human complex trait. (1999) (79)
[Angiotensin II type 1 receptor gene]. (2000) (79)
Involvement of Uric Acid Transporters in Alteration of Serum Uric Acid Level by Angiotensin II Receptor Blockers (2008) (79)
Molecular cloning and sequence analysis of cDNA encoding rat adrenal cytochrome P‐45011β (1989) (79)
Gene transfer of human prostacyclin synthase prevents neointimal formation after carotid balloon injury in rats. (1999) (78)
Expression of parathyroid hormone/parathyroid hormone-related protein receptor in vascular endothelial cells. (1998) (78)
Role of angiotensin II in high fructose-induced left ventricular hypertrophy in rats. (1993) (78)
Causal Effect of Plasminogen Activator Inhibitor Type 1 on Coronary Heart Disease (2017) (78)
Klotho protein promotes adipocyte differentiation. (2006) (78)
A novel vascular modulator, hepatocyte growth factor (HGF), as a potential index of the severity of hypertension. (1998) (78)
Human prostacyclin synthase gene and hypertension : the Suita Study. (1999) (77)
Angiogenic and antifibrotic actions of hepatocyte growth factor improve cardiac dysfunction in porcine ischemic cardiomyopathy (2006) (75)
Inhibition of NFκB activation using cis-element ‘decoy’ of NFκB binding site reduces neointimal formation in porcine balloon-injured coronary artery model (2003) (75)
Association of a Sodium Channel α Subunit Promoter Variant with Blood Pressure (2001) (74)
Analysis of Early-Phase Insulin Responses in Nonobese Subjects With Mild Glucose Intolerance (1992) (74)
Sympathetic activity and body mass index contribute to blood pressure levels. (2000) (73)
Hepatocyte growth factor prevents endothelial cell death through inhibition of bax translocation from cytosol to mitochondrial membrane. (2002) (73)
No association between alpha-adducin 460 polymorphism and essential hypertension in a Japanese population. (1998) (73)
Overexpression of prostacyclin synthase inhibits growth of vascular smooth muscle cells. (1995) (73)
Autocrine and paracrine effects of atrial natriuretic peptide gene transfer on vascular smooth muscle and endothelial cellular growth. (1994) (72)
An intronic variable number of tandem repeat polymorphisms of the cold-induced autoinflammatory syndrome 1 (CIAS1) gene modifies gene expression and is associated with essential hypertension (2006) (72)
cis Element Decoy Against Nuclear Factor-&kgr;B Attenuates Development of Experimental Autoimmune Myocarditis in Rats (2001) (72)
Changes in frequency of orthostatic hypotension in elderly hypertensive patients under medications. (1996) (70)
Pituitary-thyroid hormone periodicities in serially sampled plasma of unanesthetized rats. (1979) (70)
Alzheimer Disease–Associated Peptide, Amyloid &bgr;40, Inhibits Vascular Regeneration With Induction of Endothelial Autophagy (2009) (70)
Gene therapy for preventing neuronal death using hepatocyte growth factor: in vivo gene transfer of HGF to subarachnoid space prevents delayed neuronal death in gerbil hippocampal CA1 neurons (2001) (70)
Local delivery of E2F decoy oligodeoxynucleotides using ultrasound with microbubble agent (Optison) inhibits intimal hyperplasia after balloon injury in rat carotid artery model. (2004) (70)
Age-related association of MHC class I chain-related gene A (MICA) with type 1 (insulin-dependent) diabetes mellitus. (2000) (70)
Intravenous nicorandil in conjunction with coronary reperfusion therapy is associated with better clinical and functional outcomes in patients with acute myocardial infarction. (2003) (68)
Novel Mechanisms of Valsartan on the Treatment of Acute Myocardial Infarction Through Inhibition of the Antiadhesion Molecule Periostin (2007) (68)
Mutation of the Follicle-Stimulating Hormone Receptor Gene 5′-Untranslated Region Associated With Female Hypertension (2006) (68)
Actions of hepatocyte growth factor as a local modulator in the kidney: potential role in pathogenesis of renal disease. (1998) (68)
Cardiac free wall rupture in acute myocardial infarction: Ameliorative effect of coronary reperfusion (1992) (67)
Association of variants in critical core promoter element of angiotensinogen gene with increased risk of essential hypertension in Japanese. (1997) (67)
Adiponectin and inflammatory markers in peripheral arterial occlusive disease. (2006) (67)
Regression of Abdominal Aortic Aneurysms by Simultaneous Inhibition of Nuclear Factor &kgr;B and Ets in a Rabbit Model (2007) (66)
Nine polymorphisms of angiotensinogen gene in the susceptibility to essential hypertension. (2000) (66)
Role of angiotensin II in the regulation of a novel vascular modulator, hepatocyte growth factor (HGF), in experimental hypertensive rats. (1997) (66)
Nifedipine Indirectly Upregulates Superoxide Dismutase Expression in Endothelial Cells via Vascular Smooth Muscle Cell–Dependent Pathways (2002) (66)
Association of Trp64Arg mutation of the β3-adrenergic-receptor with NIDDM and body weight gain (1996) (66)
Lysophosphatidylcholine causes Ca2+ influx, enhanced DNA synthesis and cytotoxicity in cultured vascular smooth muscle cells. (1995) (65)
TRIC-A channels in vascular smooth muscle contribute to blood pressure maintenance. (2011) (65)
Gene Transfer of Hepatocyte Growth Factor Gene Improves Learning and Memory in the Chronic Stage of Cerebral Infarction (2006) (64)
Ubiquitin Carboxyl-Terminal Hydrolase L1, a Novel Deubiquitinating Enzyme in the Vasculature, Attenuates NF-&kgr;B Activation (2007) (64)
Alpha-adducin Gly460Trp polymorphism is associated with low renin hypertension in younger subjects in the Ohasama study (2002) (64)
Age-dependent changes in phenotypes and candidate gene analysis in a polygenic animal model of Type II diabetes mellitus; NSY mouse (2000) (64)
Hepatocyte growth factor as cardiovascular hormone: role of HGF in the pathogenesis of cardiovascular disease. (2002) (63)
Identification of Hypertension-Susceptibility Genes and Pathways by a Systemic Multiple Candidate Gene Approach: The Millennium Genome Project for Hypertension (2008) (63)
Three different mutations of presenilin 1 gene in early-onset Alzheimer's disease families (1996) (63)
Concentrations and molecular forms of human brain natriuretic peptide in plasma. (1992) (63)
Practitioner's Trial on the Efficacy of Antihypertensive Treatment in the Elderly Hypertension (The PATE-Hypertension Study) in Japan. (2000) (63)
Role of AP-1 complex in angiotensin II-mediated transforming growth factor-beta expression and growth of smooth muscle cells: using decoy approach against AP-1 binding site. (1998) (63)
Meta-analysis of the association of Trp64Arg polymorphism of beta 3-adrenergic receptor gene with body mass index. (1998) (63)
Role of transcriptional cis-elements, angiotensinogen gene-activating elements, of angiotensinogen gene in blood pressure regulation. (1996) (63)
Therapeutic angiogenesis induced by hepatocyte growth factor: potential gene therapy for ischemic diseases. (2000) (62)
Enhanced angiogenesis and improvement of neuropathy by cotransfection of human hepatocyte growth factor and prostacyclin synthase gene (2003) (62)
Enzyme-labelled immunoassay for plasma cortisol. (1977) (62)
Central Amino Acids Mediate Cardiovascular Response to Angiotensin II in the Rat (1998) (61)
Clinical evaluation of plasma des-γ-carboxy prothrombin as a marker protein of hepatocellular carcinoma in patients with tumors of various sizes (1993) (61)
Genetics of type 1 diabetes in Asian and Caucasian populations. (2007) (61)
Relative localization of angiotensin-converting enzyme, chymase and angiotensin II in human coronary atherosclerotic lesions. (1999) (60)
Analysis by the polymerase chain reaction of histocompatibility leucocyte antigen-DR9-linked susceptibility to insulin-dependent diabetes mellitus. (1992) (60)
Beta2-adrenoceptor polymorphisms relate to insulin resistance and sympathetic overactivity as early markers of metabolic disease in nonobese, normotensive individuals. (2005) (60)
Gene Therapy for Attenuating Cardiac Allograft Arteriopathy Using Ex Vivo E2F Decoy Transfection by HVJ-AVE–Liposome Method in Mice and Nonhuman Primates (2000) (60)
Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) trial of cardiovascular events in high-risk hypertensive patients: rationale, design, and methods. (2003) (60)
Age-stratified and blood-pressure-stratified effects of blood-pressure-lowering pharmacotherapy for the prevention of cardiovascular disease and death: an individual participant-level data meta-analysis (2021) (60)
Prevention of osteoporosis by angiotensin-converting enzyme inhibitor in spontaneous hypertensive rats (2009) (59)
Inhibition of neointimal formation after balloon injury by cilostazol, accompanied by improvement of endothelial dysfunction and induction of hepatocyte growth factor in rat diabetes model (2001) (59)
Angiotensin-converting enzyme I/D polymorphism and hypertension: The Ohasama study (2002) (59)
Inhibition of the p53 tumor suppressor gene results in growth of human aortic vascular smooth muscle cells. Potential role of p53 in regulation of vascular smooth muscle cell growth. (1999) (59)
Prevention of abdominal aortic aneurysms by simultaneous inhibition of NFκB and ets using chimeric decoy oligonucleotides in a rabbit model (2006) (58)
High-density association study and nomination of susceptibility genes for hypertension in the Japanese National Project. (2007) (58)
Possible participation of Fas-mediated apoptosis in the mechanism of atherosclerosis. (1997) (58)
Lack of association between angiotensin II type 1 receptor gene polymorphism and hypertension in Japanese. (2003) (57)
Upregulation of angiotensin-converting enzyme during the healing process after injury at the site of percutaneous transluminal coronary angioplasty in humans. (1997) (57)
Molecular scanning of interleukin-21 gene and genetic susceptibility to type 1 diabetes. (2007) (57)
Homozygosity mapping and Werner's syndrome (1992) (57)
A novel microsatellite polymorphism in the human OB gene: a highly polymorphic marker for linkage analysis (1996) (57)
Intravenous injection of oligodeoxynucleotides to the NF-kappaB binding site inhibits hepatic metastasis of M5076 reticulosarcoma in mice (2001) (57)
Renin-angiotensin inhibition reverses advanced cardiac remodeling in aging spontaneously hypertensive rats. (2007) (56)
Efficient in vivo gene transfer into the heart in the rat myocardial infarction model using the HVJ (Hemagglutinating Virus of Japan)--liposome method. (1997) (56)
Long-Term Follow-Up Evaluation of Results From Clinical Trial Using Hepatocyte Growth Factor Gene to Treat Severe Peripheral Arterial Disease (2012) (56)
[Linkage mapping]. (1996) (55)
Circulating factor with ouabain-like immunoreactivity in patients with primary aldosteronism. (1986) (55)
The Optimal Target Blood Pressure for Antihypertensive Treatment in Japanese Elderly Patients with High-Risk Hypertension: A Subanalysis of the Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) Trial (2008) (55)
Genetic heterogeneity in association of the SUMO4 M55V variant with susceptibility to type 1 diabetes. (2005) (54)
Calcium Channel Blocker Azelnidipine Enhances Vascular Protective Effects of AT1 Receptor Blocker Olmesartan (2004) (54)
The renin-angiotensin system, hypertension and cognitive dysfunction in Alzheimer's disease: new therapeutic potential. (2008) (54)
Plasma Atrial Natriuretic Peptide Level As an Index for the Severity of Congestive Heart Failure (1987) (54)
Association between angiotensin II type 1 receptor gene polymorphism and essential hypertension: the Ohasama Study. (2004) (54)
Leptin-Receptor Polymorphisms Relate to Obesity through Blunted Leptin-Mediated Sympathetic Nerve Activation in a Caucasian Male Population (2008) (53)
Association Between SAH, an Acyl-CoA Synthetase Gene, and Hypertriglyceridemia, Obesity, and Hypertension (2002) (53)
Inhibition of intimal hyperplasia after vein grafting by in vivo transfer of human senescent cell-derived inhibitor-1 gene (1998) (53)
Novel in vitro gene transfer method for study of local modulators in vascular smooth muscle cells. (1993) (52)
Genetics of Type 1 Diabetes: Similarities and Differences between Asian and Caucasian Populations (2006) (52)
High plasma levels of cortisol in patients with senile dementia of the Alzheimer's type. (1989) (52)
Gene–environmental interaction regarding alcohol-metabolizing enzymes in the Japanese general population (2009) (52)
Is Pulse Pressure a Predictor of New-Onset Diabetes in High-Risk Hypertensive Patients? (2010) (51)
CYP11B2 polymorphisms and home blood pressure in a population-based cohort in Japanese: the Ohasama study. (2004) (51)
A/C1166 gene polymorphism of the angiotensin II type 1 receptor (AT1) and ambulatory blood pressure: the Ohasama Study. (2003) (51)
Familial hypertension, insulin, sympathetic activity, and blood pressure elevation. (1998) (50)
Increase in plasma ouabainlike inhibitor of Na+, K+-ATPase with high sodium intake in patients with essential hypertension. (1987) (50)
Gene transfer into adult rat spinal cord using naked plasmid DNA and ultrasound microbubbles (2005) (50)
Hepatocyte growth factor (HGF) as a potential index of severity of hypertension. (1999) (50)
Inhibitory effects of NFkappaB decoy oligodeoxynucleotides on neointimal hyperplasia in a rabbit vein graft model. (2006) (50)
Hepatocyte growth factor as a potential index of complication in diabetes mellitus (1998) (49)
Tissue-specific and glucose-dependent expression of receptor genes for glucagon and glucagon-like peptide-1 (GLP-1). (1997) (49)
The effect of reduced alcohol consumption on blood pressure: a randomised, controlled, single blind study. (1987) (49)
Interleukin-6 stimulates proliferation of cultured vascular smooth muscle cells independently of interleukin-1 beta. (1991) (49)
Association between angiotensin II receptor gene polymorphism and serum angiotensin converting enzyme (SACE) activity in patients with sarcoidosis (1998) (49)
Association of Genetic Variants Influencing Lipid Levels with Coronary Artery Disease in Japanese Individuals (2012) (49)
The Combination Therapy of Hypertension to Prevent Cardiovascular Events (COPE) Trial: Rationale and Design (2005) (49)
Insulin resistance and cardiovascular complications in patients with essential hypertension. (1996) (49)
Angiotensin blockade and the progression of renal damage in the spontaneously hypertensive rat. (1993) (48)
Inhibition of growth of human vascular smooth muscle cells by overexpression of p21 gene through induction of apoptosis. (1998) (48)
and Yuhei Hypertension Uric Acid , Left Ventricular Mass Index , and Risk of Cardiovascular Disease in Essential (2006) (48)
Analyses of differential gene expression in genetic hypertensive rats by microarray. (2002) (47)
Links between hypertension and myocardial infarction. (1996) (47)
Gene Transfer of Hepatocyte Growth Factor to Subarachnoid Space in Cerebral Hypoperfusion Model (2002) (46)
Epsilon 4 allele of apolipoprotein E gene associates with lower blood pressure in young Japanese subjects: The Suita Study (2002) (46)
Leptin gene polymorphism is associated with hypertension independent of obesity. (2002) (46)
Expansion of unstable DNA region in Japanese myotonic dystrophy patients (1992) (46)
Deletion allele of the angiotensin-converting enzyme gene as a risk factor for pneumonia in elderly patients. (2002) (46)
Rebound weight gain as associated with high plasma norepinephrine levels that are mediated through polymorphisms in the beta2-adrenoceptor. (2005) (46)
Dahl's salt-resistant normotensive rat has mutations in cytochrome P450(11 beta), but the salt-sensitive hypertensive rat does not. (1993) (46)
β2- and β3-Adrenoceptor Polymorphisms Relate to Subsequent Weight Gain and Blood Pressure Elevation in Obese Normotensive Individuals (2006) (45)
Characterization of immunoreactive brain natriuretic peptide in human cardiac atrium. (1990) (45)
Significant increase in plasma immunoreactive atrial natriuretic polypeptide concentration during head-out water immersion. (1986) (45)
Renal-Protective Effect of T-and L-Type Calcium Channel Blockers in Hypertensive Patients: An Amlodipine-to-Benidipine Changeover (ABC) Study (2007) (45)
Enhanced Tumor-Specific Long-Term Immunity of Hemaggluttinating Virus of Japan-Mediated Dendritic Cell-Tumor Fused Cell Vaccination by Coadministration with CpG Oligodeoxynucleotides1 (2004) (45)
The Importance of Home Blood Pressure Measurement for Preventing Stroke and Cardiovascular Disease in Hypertensive Patients: A Sub-Analysis of the Japan Hypertension Evaluation with Angiotensin II Antagonist Losartan Therapy (J-HEALTH) Study, a Prospective Nationwide Observational Study (2008) (45)
Klotho protein activates the PKC pathway in the kidney and testis and suppresses 25-hydroxyvitamin D3 1α-hydroxylase gene expression (2004) (44)
Radioimmunoassay of human platelet-derived growth factor using monoclonal antibody toward a synthetic 73-97 fragment of its B-chain. (1989) (44)
Antisense oligodeoxynucleotide inhibition of vascular angiotensin-converting enzyme expression attenuates neointimal formation: evidence for tissue angiotensin-converting enzyme function. (2000) (44)
Genetics of insulin-dependent diabetes mellitus. (1996) (44)
Prevention of onset of Parkinson’s disease by in vivo gene transfer of human hepatocyte growth factor in rodent model: a model of gene therapy for Parkinson’s disease (2006) (44)
Increased plasma levels of the soluble form of Fas ligand in patients with acute myocardial infarction and unstable angina pectoris. (2002) (44)
Spectral change in heart rate variability in response to mental arithmetic before and after the beta-adrenoceptor blocker, carteolol (1992) (43)
Reevaluation of the association of seven candidate genes with blood pressure and hypertension: a replication study and meta-analysis with a larger sample size (2012) (43)
Alterations of bone mineral density of the femurs in hemiplegia (1995) (43)
Chronic administration of angiotensin II receptor antagonist, TCV-116, in cardiomyopathic hamsters. (1994) (43)
Combinations of olmesartan and a calcium channel blocker or a diuretic in elderly hypertensive patients: a randomized, controlled trial1 (2014) (43)
Macrophage inflammatory protein-1beta induced cell adhesion with increased intracellular reactive oxygen species. (2009) (43)
A neuropeptide Y locus on chromosome 4 cosegregates with blood pressure in the spontaneously hypertensive rat. (1993) (43)
T+31C Polymorphism of Angiotensinogen Gene and Essential Hypertension (2001) (43)
Changes in human plasma atrial natriuretic polypeptide concentration in normal subjects during passive leg raising and whole-body tilting. (1986) (42)
Carotid intima-media thickness is correlated with impairment of coronary flow reserve in hypertensive patients without coronary artery disease. (2003) (42)
Association of plasma fibrinogen level and blood pressure with diabetic retinopathy, and renal complications associated with proliferative diabetic retinopathy, in Type 2 diabetes mellitus (1999) (42)
ARB candesartan and CCB amlodipine in hypertensive patients: the CASE-J trial (2008) (42)
Survival of grafts of genetically modified cardiac myocytes transfected with FITC-labeled oligodeoxynucleotides and the β-galactosidase gene in the noninfarcted area, but not the myocardial infarcted area (1997) (42)
EGF family ligand-dependent phenotypic modulation of smooth muscle cells through EGF receptor. (2001) (41)
Genome-wide response to antihypertensive medication using home blood pressure measurements: a pilot study nested within the HOMED-BP study. (2013) (41)
Roles of TGF-beta1 and apoptosis in the progression of glomerulosclerosis in human IgA nephropathy. (2006) (41)
Length rather than a specific allele of dinucleotide repeat in the 5′ upstream region of the aldose reductase gene is associated with diabetic retinopathy (1999) (41)
Inhibition of Neointima by Angiotensin-Converting Enzyme Inhibitor in Porcine Coronary Artery Balloon-Injury Model (2001) (41)
Efficient oligonucleotide delivery using the HVJ-liposome method in the central nervous system. (1996) (40)
Upregulation of cAMP is a new functional signal pathway of Klotho in endothelial cells. (2003) (40)
Recognition of tissue- and subtype-specific modulation of angiotensin II receptors using antibodies against AT1 and AT2 receptors. (1997) (40)
Endothelin activates the vascular renin-angiotensin system in rat mesenteric arteries. (1990) (40)
Beta2-adrenoceptor polymorphisms relate to obesity through blunted leptin-mediated sympathetic activation. (2006) (40)
Efficacy and Safety of the Selective Aldosterone Blocker Eplerenone in Japanese Patients With Hypertension: A Randomized, Double‐Blind, Placebo‐Controlled, Dose‐Ranging Study (2004) (40)
Deletion polymorphism in the gene for angiotensin-converting enzyme is not a risk factor predisposing to abdominal aortic aneurysm. (1999) (40)
Role of glucose intolerance in cardiac diastolic function in essential hypertension. (1994) (40)
Changes in gene expression of the renin-angiotensin system in two-kidney, one clip hypertensive rats. (1991) (40)
Transcription factors as molecular targets: molecular mechanisms of decoy ODN and their design. (2003) (39)
Antihypertensive effects of the neutral endopeptidase inhibitor SCH 42495 in essential hypertension. (1994) (39)
Effects of Endothelin on Neuroeffector Junction in Mesenteric Arteries of Hypertensive Rats (1990) (39)
Transfection of antisense p53 tumor suppressor gene oligodeoxynucleotides into rat carotid artery results in abnormal growth of vascular smooth muscle cells. (2000) (39)
Accumulation of common polymorphisms is associated with development of hypertension: a 12-year follow-up from the Ohasama study (2010) (39)
Effect of interleukin-6 receptor blockage on renal injury in apolipoprotein E-deficient mice. (2009) (39)
Normalization of high plasma level of ouabain-like immunoreactivity in primary aldosteronism after removal of adenoma. (1988) (39)
Hypertension Accelerated Experimental Abdominal Aortic Aneurysm Through Upregulation of Nuclear Factor &kgr;B and Ets (2006) (39)
Trp64Arg mutation of beta3-adrenergic receptor in essential hypertension: insulin resistance and the adrenergic system. (1997) (39)
Relationship of bradykinin B2 receptor gene polymorphism with essential hypertension and left ventricular hypertrophy. (2004) (39)
cGMP upregulates nitric oxide synthase expression in vascular smooth muscle cells. (1995) (38)
Combination of half doses of angiotensin type 1 receptor antagonist and angiotensin-converting enzyme inhibitor in diabetic nephropathy. (2005) (38)
Hypertensive rats produced by in vivo introduction of the human renin gene. (1993) (38)
C-Reactive Protein, Left Ventricular Mass Index, and Risk of Cardiovascular Disease in Essential Hypertension (2007) (38)
Effect of Long-Term Treatment with Antihypertensive Drugs on Quality of Life of Elderly Patients with Hypertension: A Double-Blind Comparative Study between a Calcium Antagonist and a Diuretic (2000) (38)
Differences in mechanisms between weight loss-sensitive and -resistant blood pressure reduction in obese subjects. (2001) (38)
Decreased circulating levels of vitamin K and 25-hydroxyvitamin D in osteopenic elderly men. (1998) (38)
TCV‐116: A New Angiotensin II Type‐1 Receptor Antagonist (1994) (37)
valsartan in elderly isolated systolic hypertension (VALISH) study: rationale and design. (2004) (37)
Association of (pro)renin receptor gene polymorphisms with lacunar infarction and left ventricular hypertrophy in Japanese women: the Ohasama study (2011) (37)
Effects of candesartan and amlodipine on cardiovascular events in hypertensive patients with chronic kidney disease: subanalysis of the CASE-J Study (2009) (37)
A randomized, double-blind, four-arm parallel-group study of the efficacy and safety of azelnidipine and olmesartan medoxomil combination therapy compared with each monotherapy in Japanese patients with essential hypertension: the REZALT study (2009) (37)
Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population. (2010) (37)
Transfection of human HGF plasmid DNA improves limb salvage in Buerger's disease patients with critical limb ischemia. (2011) (37)
Single Nucleotide Polymorphisms in the Interleukin-6 Gene Associated with Blood Pressure and Atherosclerosis in a Japanese General Population (2005) (37)
Beta2- and beta3-adrenergic receptor polymorphisms are related to the onset of weight gain and blood pressure elevation over 5 years. (2005) (37)
Role of diabetes and obesity in outcomes of the candesartan antihypertensive survival evaluation in Japan (CASE-J) trial (2010) (37)
A novel strategy for gene therapy and gene regulation analysis using transcription factor decoy oligonucleotides. (1997) (37)
Apop-1, a Novel Protein Inducing Cyclophilin D-dependent but Bax/Bak-related Channel-independent Apoptosis* (2006) (37)
Gene transfer of human hepatocyte growth factor into rat skin wounds mediated by liposomes coated with the sendai virus (hemagglutinating virus of Japan). (2002) (36)
Prevention of amyloid β-induced memory impairment by fluvastatin, associated with the decrease in amyloid β accumulation and oxidative stressin amyloid β injection mouse model (2008) (36)
Serum dopamine-beta-hydroxylase activity in parents and children. (1975) (36)
Pharmacogenetic Analysis of the Effect of Angiotensin-Converting Enzyme Inhibitor on Restenosis After Percutaneous Transluminal Coronary Angioplasty (1999) (36)
Mouse models of type 1 and type 2 diabetes derived from the same closed colony: genetic susceptibility shared between two types of diabetes. (2004) (35)
Clinical Usefulness and Limitations of Brachial-Ankle Pulse Wave Velocity in the Evaluation of Cardiovascular Complications in Hypertensive Patients (2006) (35)
Calcitonin Receptor Gene Polymorphism in Japanese Women: Correlation with Body Mass and Bone Mineral Density (2001) (35)
Bone Mineral Density of the Lumbar Spine in Psoriatic Patients with Long Term Etretinate Therapy (1994) (35)
Suppression of synthesis and release of glucagon by glucagon-like peptide-1 (7-36 amide) without affect on mRNA level in isolated rat islets. (1990) (35)
Low Potentiality of Angiotensin-Converting Enzyme Gene Insertion/Deletion Polymorphism as a Useful Predictive Marker for Carotid Atherogenesis in a Large General Population of a Japanese City: The Suita Study (2001) (35)
Model of Vasculogenesis from Embryonic Stem Cells for Vascular Research and Regenerative Medicine (2006) (35)
Expression of hepatocyte growth factor and c-Met after spinal cord injury in rats (2007) (35)
Changes in plasma lipids and uric acid with sodium loading and sodium depletion in patients with essential hypertension. (1988) (35)
Potential role of CYLD (Cylindromatosis) as a deubiquitinating enzyme in vascular cells. (2008) (35)
Improvement of accessory symptoms of hypertension by TSUMURA Orengedokuto Extract, a four herbal drugs containing Kampo-Medicine Granules for ethical use: a double-blind, placebo-controlled study. (2006) (35)
The role of activated vascular angiotensin II generation in vascular hypertrophy in one-kidney, one clip hypertensive rats (1993) (34)
Low density lipoprotein receptor‐related protein gene polymorphisms and risk for late‐onset Alzheimer's disease in a Japanese population (2000) (34)
[Direct in vivo gene introduction into rat kidney]. (1992) (34)
Anti‐apoptotic action of hepatocyte growth factor through mitogen‐activated protein kinase on human aortic endothelial cells (2000) (34)
Hypotensive effect of long-term oral calcium supplementation in elderly patients with essential hypertension. (1986) (34)
Inverse relation between severity of psoriasis and serum 1,25-dihydroxy-vitamin D level. (1990) (34)
Elevated amyloid β protein(1-40) level induces CREB phosphorylation at serine-133 via p44/42 MAP kinase (Erk1/2)-dependent pathway in rat pheochromocytoma PC12 cells (1997) (34)
Kynureninase is a novel candidate gene for hypertension in spontaneously hypertensive rats. (2002) (34)
Association of gene polymorphism of the fat-mass and obesity-associated gene with insulin resistance in Japanese (2010) (34)
Interaction of BMP10 with Tcap may modulate the course of hypertensive cardiac hypertrophy. (2007) (34)
Effect of 1-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine inhibitor on the reduction of one-kidney, one clip hypertension after unclipping in the rat. (1984) (34)
Rapid Serodiagnosis of Active Pulmonary Mycobacterium tuberculosis by Analysis of Results from Multiple Antigen-Specific Tests (2004) (34)
Association of small ubiquitin-like modifier 4 (SUMO4) variant, located in IDDM5 locus, with type 2 diabetes in the Japanese population. (2007) (33)
Transcription factor decoy for NFkappaB inhibits TNF-alpha-induced cytokine and adhesion molecule expression in vivo. (2000) (33)
Insulin-mediated regulation of the endothelial renin–angiotensin system and vascular cell growth (2004) (33)
Impact of serum uric acid on renal function and cardiovascular events in hypertensive patients treated with losartan (2012) (33)
Two different coronary blood flow velocity patterns in thrombolysis in myocardial infarction flow grade 2 in acute myocardial infarction: insight into mechanisms of microvascular dysfunction. (2002) (33)
[Guidelines on Treatment of Hypertension in the Elderly--2002 Revised Version]. (2002) (33)
On-Treatment Blood Pressure and Cardiovascular Outcomes in Older Adults With Isolated Systolic Hypertension (2017) (33)
Novel therapeutic strategy for atherosclerosis: ribozyme oligonucleotides against apolipoprotein(a) selectively inhibit apolipoprotein(a) but not plasminogen gene expression. (1998) (33)
Additive effects of nicorandil on coronary blood flow during continuous administration of nitroglycerin. (2001) (33)
CALCIUM METABOLISM IN ELDERLY HYPERTENSIVE PATIENTS: POSSIBLE PARTICIPATION OF EXAGGERATED SODIUM, CALCIUM AND PHOSPHATE EXCRETION (1991) (33)
Antihypertensive Efficacy and Safety of Fixed-Dose Combination Therapy with Losartan plus Hydrochlorothiazide in Japanese Patients with Essential Hypertension (2007) (33)
Low-dose doxazosin improved aortic stiffness and endothelial dysfunction as measured by noninvasive evaluation. (2002) (32)
Combination therapy for hypertension in the elderly: a sub-analysis of the Combination Therapy of Hypertension to Prevent Cardiovascular Events (COPE) Trial (2012) (32)
Polymorphism of the apolipoprotein E and angiotensin-converting enzyme genes in Japanese subjects with silent myocardial ischemia. (1996) (32)
A Polymorphism Regulates CYP4A11 Transcriptional Activity and Is Associated With Hypertension in a Japanese Population (2008) (32)
Inhibition of TNF-α, Induced Cytokine and Adhesion Molecule (2001) (32)
Association of Pro12Ala polymorphism of PPARgamma gene with insulin resistance and related diseases. (2004) (32)
Association of a sodium channel alpha subunit promoter variant with blood pressure. (2002) (32)
Effects of 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet activating factor) on cardiac function in perfused guinea-pig heart. (1985) (32)
Hutchinson-Gilford progeria syndrome in a 45-year-old man. (1986) (32)
Different mechanisms in weight loss-induced blood pressure reduction between a calorie-restricted diet and exercise (2012) (32)
Impaired endothelial dysfunction in diabetes mellitus rats was restored by oral administration of prostaglandin I2 analogue. (2002) (31)
Arterial stiffness index: A new evaluation for arterial stiffness in elderly patients with essential hypertension (2002) (31)
Comparison of the inhibitions of proliferation of normal and psoriatic fibroblasts by 1 alpha,25-dihydroxyvitamin D3 and synthetic analogues of vitamin D3 with an oxygen atom in their side chain. (1989) (31)
Role of tissue renin angiotensin system in two-kidney, one-clip hypertensive rats. (1993) (31)
Gene Polymorphism of Myospryn (Cardiomyopathy-Associated 5) Is Associated with Left Ventricular Wall Thickness in Patients with Hypertension (2007) (31)
Difference in the incidence of cough induced by angiotensin converting enzyme inhibitors: a comparative study using imidapril hydrochloride and enalapril maleate. (1999) (31)
Inhibition of NFkappaB activation using cis-element 'decoy' of NFkappaB binding site reduces neointimal formation in porcine balloon-injured coronary artery model. (2003) (31)
FS2. a mamba venom toxin, is a specific blocker of the L-type calcium channels. (1994) (31)
Calciseptine binding to a 1,4-dihydropyridine recognition site of the L-type calcium channel of rat synaptosomal membranes. (1993) (30)
Evaluation of genetic loci influencing adult height in the Japanese population (2009) (30)
Sjögren's syndrome with pleural effusion. (1995) (30)
Effects of beraprost sodium, a stable analogue of prostacyclin, on hyperplasia, hypertrophy and glycosaminoglycan synthesis of rat aortic smooth muscle cells. (1993) (30)
Ouabain-like and non-ouabain-like factors in plasma of patients with essential hypertension. (1987) (30)
In vivo transfer efficiency of antisense oligonucleotides into the myocardium using HVJ-liposome method. (1997) (30)
Serum interleukin-15 concentration in patients with essential hypertension. (2005) (29)
Mitogenic Activity of Oxidized Lipoprotein (a) on Human Vascular Smooth Muscle Cells (2002) (29)
Efficacy and Safety of Long-Term Losartan Therapy Demonstrated by a Prospective Observational Study in Japanese Patients with Hypertension: The Japan Hypertension Evaluation with Angiotensin II Antagonist Losartan Therapy (J-HEALTH) Study (2008) (29)
Mechanisms mediating postprandial blood pressure reduction in young and elderly subjects. (1996) (29)
Serum hepatocyte growth factor concentration is correlated with the forearm vasodilator response in hypertensive patients. (2002) (29)
Inhibition of ets, an essential transcription factor for angiogenesis, to prevent the development of abdominal aortic aneurysm in a rat model (2005) (29)
Phosphorylation of p 38 Mitogen-Activated Protein Kinase Downstream of Bax-Caspase-3 Pathway Leads to Cell Death Induced by High D-Glucose in Human Endothelial Cells (2001) (28)
Japanese individuals do not harbor the T594M mutation but do have the P592S mutation in the C‐terminus of the β‐subunit of the epithelial sodium channel: the Ohasama Study (2000) (28)
Transcription factor decoy to study the molecular mechanism of negative regulation of renin gene expression in the liver in vivo. (1999) (28)
Molecular strategy using cis-element ‘decoy’ of E2F binding site inhibits neointimal formation in porcine balloon-injured coronary artery model (2002) (28)
Linkage disequilibrium and haplotype studies of chromosome 8p 11.1-21.1 markers and Werner syndrome. (1994) (28)
MHC-linked diabetogenic gene of the NOD mouse: molecular mapping of the 3' boundary of the diabetogenic region. (1993) (28)
NFκB decoy oligodeoxynucleotides ameliorates osteoporosis through inhibition of activation and differentiation of osteoclasts (2006) (28)
Effects of an Angiotensin II Receptor Antagonist, CV‐11974, on Angiotensin II‐Induced Increases in Cytosolic Free Calcium Concentration, Hyperplasia, and Hypertrophy of Cultured Vascular Smooth Muscle Cells (1994) (28)
EFFECT OF AN ANTIHYPERTENSIVE DRUG ON BRAIN ANGIOTENSIN II LEVELS IN RENAL AND SPONTANEOUSLY HYPERTENSIVE RATS (1995) (28)
Antioxidant, probucol, can inhibit the generation of hydrogen peroxide in islet cells induced by macrophages and prevent islet cell destruction in NOD mice. (1995) (28)
Relationship between the achieved blood pressure and the incidence of cardiovascular events in Japanese hypertensive patients with complications: a sub-analysis of the CASE-J trial (2009) (27)
Comprehensive Geriatric Assessment is a useful predictive tool for postoperative delirium after gastrointestinal surgery in old‐old adults (2016) (27)
Role of acetyl glyceryl ether phosphorylcholine in blood pressure regulation in rats. (1985) (27)
Prevention of renal damage by angiotensin II blockade, accompanied by increased renal hepatocyte growth factor in experimental hypertensive rats. (1999) (27)
Serum deprivation-induced apoptosis accompanied by up-regulation of p53 and bax in human aortic vascular smooth muscle cells. (1997) (27)
Hypoxia Stimulates Release of the Soluble Form of Fas Ligand That Inhibits Endothelial Cell Apoptosis (2001) (27)
Lack of correlation between Mbo I restriction fragment length polymorphism of renin gene and essential hypertension in Japanese. (2001) (27)
Guidelines for treatment of hypertension in the elderly--2002 revised version. (2003) (26)
Preferable effects of olmesartan/calcium channel blocker to olmesartan/diuretic on blood pressure variability in very elderly hypertension: COLM study subanalysis (2015) (26)
Additive interaction of metabolic syndrome and chronic kidney disease on cardiac hypertrophy, and risk of cardiovascular disease in hypertension. (2010) (26)
Combination therapy of hypertension in the elderly: a subgroup analysis of the Combination of OLMesartan and a calcium channel blocker or diuretic in Japanese elderly hypertensive patients trial (2014) (26)
Increase in nuclease resistance and incorporation of NF‐κB decoy oligodeoxynucleotides by modification of the 3′‐terminus (2007) (26)
Guidelines for Hypertension in the Elderly (1999) (26)
Clinical significance of left ventricular hypertrophy and changes in left ventricular mass in high-risk hypertensive patients: a subanalysis of the Candesartan Antihypertensive Survival Evaluation in Japan trial (2009) (26)
High-Resolution Mapping for Essential Hypertension Using Microsatellite Markers (2007) (26)
Effects of Angiotensin II Type 1 Receptor Gene Polymorphisms on Insulin Resistance in a Japanese General Population: The Tanno-Sobetsu Study (2006) (26)
Endothelin stimulates Na+/H+ exchange in vascular smooth muscle cells. (1990) (26)
The metabolic syndrome in the Asian population (2005) (25)
Combination therapy for hypertension in patients with CKD: a subanalysis of the Combination Therapy of Hypertension to Prevent Cardiovascular Events trial (2013) (25)
Association of Sodium Channel &ggr;-Subunit Promoter Variant With Blood Pressure (2001) (25)
Hypoxia-induced renal epithelial cell death through caspase-dependent pathway: role of Bcl-2, Bcl-xL and Bax in tubular injury. (2004) (25)
Clinical applications of synthetic angiotensin II analogue. (1974) (25)
Vascular signaling pathways in the metabolic syndrome (2002) (25)
Association of I27L polymorphism of hepatocyte nuclear factor-1 alpha gene with high-density lipoprotein cholesterol level. (2003) (25)
Gene therapy in vascular medicine: recent advances and future perspectives. (2001) (25)
Increase in peripheral blood flow by intravenous administration of prostaglandin E1 in patients with peripheral arterial disease, accompanied by up-regulation of hepatocyte growth factor. (2004) (25)
Evaluation of the Antiobesity Effects of an Amino Acid Mixture and Conjugated Linoleic Acid on Exercising Healthy Overweight Humans: A Randomized, Double-blind, Placebo-controlled Trial (2010) (25)
Nifedipine upregulates manganese superoxide dismutase expression in vascular smooth muscle cells via endothelial cell-dependent pathways. (2003) (25)
Eicosapentaenoic Acid Protects Endothelial Cells Against Anoikis Through Restoration of cFLIP (2003) (25)
Tolerability and safety of a calcium channel blocker in comparison with a diuretic in the treatment of elderly patients with hypertension: secondary analysis of the NICS-EH. (2001) (25)
In vivo evidence of the importance of cardiac angiotensin-converting enzyme in the pathogenesis of cardiac hypertrophy. (2000) (25)
Comparison of strict- and mild-blood pressure control in elderly hypertensive patients: a per-protocol analysis of JATOS (2010) (25)
Changes in autonomic activity and baroreflex sensitivity with the hypertension process and age in rats (2003) (25)
Prevention of amyloid beta-induced memory impairment by fluvastatin, associated with the decrease in amyloid beta accumulation and oxidative stress in amyloid beta injection mouse model. (2008) (25)
Co-existent primary hypothyroidism and isolated ACTH deficiency. (1976) (25)
Targeted gene therapy for rat glomerulonephritis using HVJ‐immunoliposomes (2002) (25)
In vivo gene transfer of insulin gene into neonatal rats by the HVJ-liposome method resulted in sustained transgene expression. (1996) (25)
Absence of association of TAP and LMP genes with type 1 (insulin-dependent) diabetes mellitus. (1994) (25)
Deletion of CDKAL1 Affects High-Fat Diet–Induced Fat Accumulation and Glucose-Stimulated Insulin Secretion in Mice, Indicating Relevance to Diabetes (2012) (24)
Open clinical studies on a new angiotensin II receptor antagonist, TCV 116. (1994) (24)
Identification of 21 single nucleotide polymorphisms in human hepatocyte growth factor gene and association with blood pressure and carotid atherosclerosis in the Japanese population. (2004) (24)
High Plasma Norepinephrine Levels Associated with β2-Adrenoceptor Polymorphisms Predict Future Renal Damage in Nonobese Normotensive Individuals (2007) (24)
Role of endothelin-1 induced by insulin in the regulation of vascular cell growth. (2003) (24)
Nifedipine Inhibits Vascular Smooth Muscle Cell Dedifferentiation via Downregulation of Akt Signaling (2010) (24)
Hemodynamic, renal, and hormonal responses to alpha‐human atrial natriuretic peptide in patients with congestive heart failure (1987) (24)
Changes in plasma renin activity and aldosterone concentration in response to endothelin injection in dogs. (1989) (24)
Detection of a premutation in Japanese myotonic dystrophy. (1994) (24)
Effects of the angiotensin II receptor antagonist, TCV-116, on blood pressure and the renin-angiotensin system in healthy subjects. (1994) (24)
Serum thyrotropin and thyroid hormones in the course of subacute thyroiditis. (1973) (24)
Potential therapeutic applications of decoy oligonucleotides. (2002) (23)
Exogenous ouabain is accumulated in the adrenals and mimics the kinetics of endogenous digitalis-like factor in rats. (1998) (23)
Differences in insulin and sympathetic responses to glucose ingestion due to family history of hypertension. (1996) (23)
Effects of antihypertensive drugs and gene variants in the renin-angiotensin system. (2001) (23)
Development of Antibody Against Epitope of Lipoprotein(a) Modified by Oxidation: Evaluation of New Enzyme-Linked Immunosorbent Assay for Oxidized Lipoprotein(a) (2000) (23)
Susceptibility to streptozotocin-induced diabetes is mapped to mouse chromosome 11. (2005) (23)
Peripheral vs. central blockade of the renin-angiotensin system in spontaneously hypertensive rats: comparison of novel AT1 receptor antagonist TCV-116 with angiotensin converting enzyme inhibitor delapril (1993) (23)
Genetic impact on uric acid concentration and hyperuricemia in the Japanese population. (2013) (23)
Renal handling of glycated albumin in non-insulin-dependent diabetes mellitus with nephropathy. (1991) (23)
A case of adrenal tumor producing renin, aldosterone, and sex steroid hormones. (1986) (22)
Effect of Age on Active and Inactive Plasma Renin in Normal Subjects and in Patients with Essential Hypertension * (1981) (22)
Role of parathyroid hormone-related protein in the proliferation of vascular smooth muscle cells. (1995) (22)
Effect of kihito extract granules on cognitive function in patients with Alzheimer's‐type dementia (2007) (22)
All patients with Werner's syndrome are insulin resistant, but only those who also have impaired insulin secretion develop overt diabetes. (1999) (22)
Effects of combination olmesartan medoxomil plus azelnidipine versus monotherapy with either agent on 24-hour ambulatory blood pressure and pulse rate in Japanese patients with essential hypertension: additional results from the REZALT study. (2010) (22)
Enhanced Therapeutic Angiogenesis by Cotransfection of Prostacyclin Synthase Gene or Optimization of Intramuscular Injection of Naked Plasmid DNA (2003) (22)
Potential role of a novel vascular modulator, hepatocyte growth factor (HGF), in cardiovascular disease: characterization and regulation of local HGF system. (1997) (22)
Finger print deposits of the kidney in pure monoclonal IgG kappa cryoglobulinemia. (1979) (22)
Impact of Blood Pressure Control on Cardiovascular Events in 26,512 Japanese Hypertensive Patients: The Japan Hypertension Evaluation with Angiotensin II Antagonist Losartan Therapy (J-HEALTH) Study, a Prospective Nationwide Observational Study (2008) (22)
Usefulness of a new grading system based on coronary flow velocity pattern in predicting outcome in patients with acute myocardial infarction having percutaneous coronary intervention. (2005) (22)
Allelic variation in class I K gene as candidate for a second component of MHC-linked susceptibility to Type 1 diabetes in non-obese diabetic mice (2004) (22)
Insulin resistance is related to silent cerebral infarction in patients with essential hypertension. (1997) (22)
Effects of calcium channel blocker-based combinations on intra-individual blood pressure variability: post hoc analysis of the COPE trial (2015) (22)
Effects of calcium channel blocker-based combinations on intra-individual blood pressure variability: post hoc analysis of the COPE trial (2015) (22)
Hepatocyte growth factor as potential cardiovascular therapy (2005) (22)
Inhibition of experimental abdominal aortic aneurysm progression by nifedipine. (2008) (21)
Genetic association study between senile dementia of Alzheimer's type and APOE/C1/C2 gene cluster. (1996) (21)
Free and total dopamine in human plasma: effects of posture, age and some pathophysiological conditions. (1995) (21)
Food hardness as environmental factor in development of type 2 diabetes. (2006) (21)
Pilot study of a new angiotensin II receptor antagonist, TCV-116: effects of a single oral dose on blood pressure in patients with essential hypertension. (1993) (21)
Renin Inhibitor and Converting Enzyme Inhibitors Suppress Vascular Angiotensin II (1989) (21)
DIFFERENTIAL CONTROL OF VASCULAR TONE AND HEART RATE BY DIFFERENT AMINO ACID NEUROTRANSMITTERS IN THE ROSTRAL VENTROLATERAL MEDULLA OF THE RAT (1994) (21)
The effect of aging on urinary kallikrein excretion in normotensive subjects and in patients with essential hypertension. (1981) (21)
Comparison of effects of a potassium channel opener BRL34915, a specific potassium ionophore valinomycin and calcium channel blockers on endothelin-induced vascular contraction. (1989) (21)
Systemic administration of HVJ viral coat-liposome complex containing human insulin vector decreases glucose level in diabetic mouse: A model of gene therapy. (2000) (20)
Global challenge for overcoming high blood pressure: Fukuoka Statement, 19 October 2006. (2007) (20)
Gene therapy with transcription factor decoy oligonucleotides as a potential treatment for cardiovascular diseases. (2003) (20)
Endothelin-1 enhances nitric oxide-induced cytotoxicity in vascular smooth muscle. (1995) (20)
Pranidipine enhances the action of nitric oxide released from endothelial cells. (2000) (20)
Insulin gene region contributes to genetic susceptibility to, but may not to low incidence of, insulin-dependent diabetes mellitus in Japanese. (1997) (20)
Plasma norepinephrine and dietary sodium intake in normal subjects and patients with essential hypertension. (1983) (20)
Negative feedback regulation of activated macrophages via Fas-mediated apoptosis. (2000) (20)
Hypotensive mechanism of acetyl glyceryl ether phosphorylcholine (AGEPC) in dogs. Effects on hemodynamics and humoral factors. (1985) (20)
Analysis of candidate genes for insulin resistance in essential hypertension. (1996) (20)
Variation in OSBPL10 is associated with dyslipidemia (2010) (20)
[Gene therapy for cardiovascular disease]. (1993) (20)
No influence of tumor growth by intramuscular injection of hepatocyte growth factor plasmid DNA: safety evaluation of therapeutic angiogenesis gene therapy in mice. (2004) (20)
Comparative study of the effects of three angiotensin converting enzyme inhibitors on the cough reflex. (1991) (20)
Increased plasma norepinephrine in young patients with essential hypertension under three sodium intakes. (1984) (20)
Fas Signaling Induces Akt Activation and Upregulation of Endothelial Nitric Oxide Synthase Expression (2004) (20)
Insulin secretion to glucose as well as nonglucose stimuli is impaired in spontaneously diabetic Nagoya-Shibata-Yasuda mice. (2001) (19)
Endothelin-1 in cerebrospinal fluid in elderly patients with hypertension and dementia. (1994) (19)
Activation of the brain angiotensin system by in vivo human angiotensin-converting enzyme gene transfer in rats. (1999) (19)
A mutation in the glucagon receptor gene (Gly40Ser): heterogeneity in the association with diabetes mellitus (1995) (19)
Genetic Influences of β-Adrenoceptor Polymorphisms on Arterial Functional Changes and Cardiac Remodeling in Hypertensive Patients (2006) (19)
Tissue Inhibitor of Metalloproteinase-3 Plays Important Roles in the Kidney Following Unilateral Ureteral Obstruction (2006) (19)
Possible participation of calcium-regulating factors in senile dementia in elderly female subjects. (1990) (19)
Congenic Mapping and Candidate Sequencing of Susceptibility Genes for Type 1 Diabetes in the NOD Mouse (2003) (19)
Risk factors for pressure ulcers in bedridden elderly subjects: Importance of turning over in bed and serum albumin level (2001) (19)
Fatty liver and obesity: phenotypically correlated but genetically distinct traits in a mouse model of type 2 diabetes (2007) (19)
Potent hypotensive activity of 1-O-hexadecyl-2-O-acetyl-SN-glycero-3-phosphocholine in spontaneously hypertensive rat. (1982) (19)
Novel molecular therapeutic approach to cardiovascular disease based on hepatocyte growth factor. (2000) (19)
Composite malignant pheochromocytoma with malignant peripheral nerve sheath tumour: a case with 28 years of tumour‐bearing history (2007) (19)
G2736A polymorphism of thiazide-sensitive Na-Cl cotransporter gene predisposes to hypertension in young women (2004) (19)
Comparison of olmesartan combined with a calcium channel blocker or a diuretic in elderly hypertensive patients (COLM Study): safety and tolerability (2014) (19)
Tissue Inhibitor of Metalloproteinase-3 Deficiency Inhibits Blood Pressure Elevation and Myocardial Microvascular Remodeling Induced by Chronic Administration of Nω-Nitro-L-Arginine Methyl Ester in Mice (2007) (19)
Application of decoy oligodeoxynucleotides-based approach to renal diseases. (2004) (19)
Klotho gene delivery suppresses oxidative stress in vivo (2007) (19)
Therapeutic effect of intra‐articular injection of ribbon‐type decoy oligonucleotides for hypoxia inducible factor‐1 on joint contracture in an immobilized knee animal model (2016) (19)
Development of novel decoy oligonucleotides: advantages of circular dumb-bell decoy. (2003) (19)
Autoimmune neutropenia with anti-neutrophil autoantibody associated with Sjögren's syndrome. (1990) (19)
Practitioner's Trial on the Efficacy of Antihypertensive Treatment in Elderly Patients with Hypertension II (PATE‐Hypertension II study) in Japan (2011) (18)
Effect of manidipine, a novel calcium channel blocker, on quality of life in hypertensive patients. (1992) (18)
Plasma renin activity and aldosterone concentration of patients with hyperthyroidism and hypothyroidism. (1973) (18)
Association of a mast cell chymase gene variant with HDL cholesterol, but not with blood pressure in the Ohasama study. (2002) (18)
Radioimmunoassay of Human Platelet-Derived Growth Factor Using Monoclonal Antibody Toward a Synthetic 73-97 Fragment of its B-Chain (1989) (18)
Parathyroid Hormone–Related Protein Inhibits Endothelin-1 Production (1996) (18)
Needleless in vivo gene transfer into muscles by jet injection in combination with electroporation (2004) (18)
Hypotensive effect associated with a phospholipase C-delta 1 gene mutation in the spontaneously hypertensive rat. (1992) (18)
Synergism of intraventricular NaCl infusion and subpressor angiotensins in rats. (1989) (18)
Improvement of endothelial dysfunction by angiotensin II blockade accompanied by induction of vascular hepatocyte growth factor system in diabetic spontaneously hypertensive rats (2003) (18)
Molecular Delivery System for Antisense Oligonucleotides: Enhanced Effectiveness of Antisense Oligonucleotides by HVJ-liposome Mediated Transfer (1997) (18)
Asp905Tyr Polymorphism of the Gene for the Skeletal Muscle-Specific Glycogen-Targeting Subunit of Protein Phosphatase 1 in NIDDM (1998) (18)
Clinical evaluation of delapril in Japan. Report from the Japan Study Group on Delapril. (1991) (17)
Beneficial effect of laughter therapy on physiological and psychological function in elders (2018) (17)
Hyperthyroidism associated with autoimmune hemolytic anemia and periodic paralysis: a report of a case in which antihyperthyroid therapy alone was effective against hemolysis. (1987) (17)
Paternal-maternal effects on phenotypic characteristics in spontaneously diabetic Nagoya-Shibata-Yasuda mice. (2000) (17)
[Effect of estriol and bone mineral density of lumbar vertebrae in elderly and postmenopausal women]. (1996) (17)
Angiotensinogen gene-activating elements regulate blood pressure in the brain. (1999) (17)
Interleukin-2 modulates the responsiveness to angiotensin II in cultured vascular smooth muscle cells. (1997) (17)
Essential role of HGF (hepatocyte growth factor) in blood formation in Xenopus. (2004) (17)
Amino acids in the medulla oblongata contribute to baroreflex modulation by angiotensin II (1995) (17)
In vivo transfer of gene and oligodeoxynucleotides into skin of fetal rats by incubation in amniotic fluid. (1996) (17)
High-level expression of interleukin-4 following electroporation-mediated gene transfer accelerates Type 1 diabetes in NOD mice. (2003) (17)
Oligonucleotide-Based Gene Therapy for Cardiovascular Disease (1998) (17)
Evaluation of orthostatic hypotension using power spectral analysis. (1993) (17)
Analysis and comparison of new candidate loci for hypertension between genetic hypertensive rat strains. (1996) (17)
T+31C polymorphism of angiotensinogen gene and nocturnal blood pressure decline: the Ohasama study. (2002) (17)
Contribution of a vascular modulator, hepatocyte growth factor (HGF), to the pathogenesis of cardiovascular disease. (1998) (17)
Oncogenic osteomalacia secondary to nasal tumor with decreased urinary excretion of cAMP (2001) (17)
Trinucleotide repeats of programmed cell death-1 gene are associated with susceptibility to type 1 diabetes mellitus. (2007) (17)
Effect of angiotensin II receptor blocker, olmesartan, on turnover of bone metabolism in bedridden elderly hypertensive women with disuse syndrome (2015) (17)
Glucose and Lipid Metabolism During Long-Term Lisinopril Therapy in Hypertensive Patients (1990) (17)
Acute hyperinsulinemia reduces plasma leptin levels in insulin-sensitive Japanese men. (2005) (16)
Prevalence of hyperinsulinemia in young, nonobese Japanese men (1997) (16)
Effect of angiotensinogen on blood pressure regulation in normotensive rats: application of a loss of function approach (1995) (16)
T/G polymorphism at intron 9 of presenilin 1 gene is associated with, but not responsible for sporadic late-onset Alzheimer's disease in Japanese population (1997) (16)
EFFECT OF LONG‐TERM TREATMENT WITH AN ANGIOTENSIN‐CONVERTING ENZYME INHIBITOR ON THE RENIN‐ANGIOTENSIN SYSTEM IN SPONTANEOUSLY HYPERTENSIVE RATS (1991) (16)
Detection of common single nucleotide polymorphisms synthesizing quantitative trait association of rarer causal variants. (2011) (16)
Blood pressure response to dietary calcium intervention in humans. (1990) (16)
Calmodulin levels in hypertensive rats. (1985) (16)
A new sensitive direct radioimmunoassay for human plasma renin and its clinical application. (1984) (16)
Does a common pathophysiological basis exist in the association of ulcerative colitis and Takayasu's aortitis? Report of a case. (1989) (16)
Functional polymorphism in Z-DNA-forming motif of promoter of SLC11A1 gene and type 1 diabetes in Japanese subjects: association study and meta-analysis. (2005) (16)
Serum DBH in three forms of acute stress. (1974) (16)
Renoprotective effect of N-type Ca channel blockade in diabetic nephropathy. (2007) (16)
Responses of active and inactive plasma renin and changes in urinary kallikrein and plasma prekallikrein to various conditions in normal subjects. (1982) (16)
Antisense oligonucleotides directed at cell cycle regulatory genes as strategy for restenosis therapy. (1993) (16)
Effect of captopril on angiotensin II release from vascular tissues in rats. (1987) (16)
The effect of VEGF on blood vessels and blood cells during Xenopus development. (2006) (16)
A randomised controlled trial for the evaluation of risk for type 2 diabetes in hypertensive patients receiving thiazide diuretics: Diuretics In the Management of Essential hypertension (DIME) study (2014) (16)
Studies on the renin-angiotensin-aldosterone system in elderly hypertensive patients with an angiotensin II antagonist. (1979) (16)
Effect of metoclopramide-induced prolactin on aldosterone secretion in normal subjects. (1977) (16)
Association of SUMO4, as a Candidate Gene for IDDM5, with Susceptibility to Type 1 Diabetes in Asian Populations (2006) (15)
A novel purification method of human renin. (1983) (15)
Long-term therapy with terazosin may improve glucose and lipid metabolism in hypertensives: a multicenter prospective study. (1994) (15)
Association of blood pressure control and metabolic syndrome with cardiovascular risk in elderly Japanese: JATOS study. (2011) (15)
High-resolution separation of PCR product and gene diagnosis by capillary gel electrophoresis. (1994) (15)
Renal tubular function affects glycosuria-related urinary excretion of 1,5-anhydroglucitol. (1999) (15)
Improvement of survival of skin flaps by combined gene transfer of hepatocyte growth factor and prostacyclin synthase (2007) (15)
A case of normoreninemic, normotensive primary aldosteronism associated with essential hypertension and nephrocalcinosis. (1981) (15)
Radioimmunoassay of atrial natriuretic polypeptide in heat-treated human plasma. (1987) (15)
Detection and quantification of embolic particles during percutaneous coronary intervention to stable plaque: It correlates to coronary flow dynamics and myocardial damage (2007) (15)
Enhanced tumor-specific long-term immunity of hemagglutinating [correction of hemaggluttinating] virus of Japan-mediated dendritic cell-tumor fused cell vaccination by coadministration with CpG oligodeoxynucleotides. (2004) (15)
Radioimmunoassay of metanephrine and normetanephrine for diagnosis of pheochromocytoma. (1986) (15)
T+31C polymorphism (M235T) of the angiotensinogen gene and home blood pressure in the Japanese general population: the Ohasama Study. (2003) (15)
Effects of oral and intravenous administrations of dopamine and L-dopa on plasma levels of two isomers of dopamine sulfate in man. (1987) (15)
Effects of aging on human plasma renin: simultaneous multiple assays of enzyme activity and immunoactivity of plasma renin. (1989) (15)
Guidelines for hypertension in the elderly--1999 revised version. Ministry of Health and Welfare of Japan. (1999) (15)
Aspartic acid at position 57 of the HLA-DQ beta chain is not protective against insulin-dependent diabetes mellitus in Japanese people. (1990) (15)
Fas promoter region gene polymorphism is associated with an increased risk for myocardial infarction (2009) (15)
Effects of two angiotensin II analogous on blood pressure in normal subjects with various sodium balances. (1977) (14)
The Effect of Low Dose Carvedilol on Circadian Variation of Blood Pressure in Patients with Essential Hypertension (1987) (14)
Long-term effects of candesartan and amlodipine on cardiovascular morbidity and mortality in Japanese high-risk hypertensive patients: the Candesartan Antihypertensive Survival Evaluation in Japan Extension Study (CASE-J Ex) (2011) (14)
Hypertension attenuates the efficacy of hypoglycemic therapy for preserving coronary flow reserve in patients with type 2 diabetes. (2002) (14)
A new Lp(a) assay that is unaffected by apo(a) size polymorphism. (1999) (14)
Role of the renin-angiotensin system in hypertension in the elderly. (1994) (14)
Inhibition of TNF-alpha, induced cytokine and adhesion molecule. Expression in glomerular cells in vitro and in vivo by transcription factor decoy for NFkappaB. (2001) (14)
Endogenous platelet-activating factor and anti-platelet-activating factor in patients with renovascular hypertension. (1988) (14)
Predominance of nocturnal sympathetic nervous activity in salt-sensitive normotensive subjects. (1996) (14)
The Gene for Human IL‐21 and Genetic Susceptibility to Type 1 Diabetes in the Japanese (2006) (14)
Endothelin-1 enhances nitric oxide-induced cell death in cultured vascular smooth-muscle cells. (1998) (14)
A common mutation of low-density lipoprotein receptor gene is associated with essential hypertension among Japanese (2001) (14)
Association of TNFRSF4 gene polymorphisms with essential hypertension (2008) (14)
Effects of 1, 25-dihydroxyvitamin D3 on the synthesis of DNA and glycosaminoglycans by rat aortic smooth muscle cells in vitro (1990) (14)
Regression of hypertension-induced vascular hypertrophy by an ACE inhibitor and calcium antagonist in the spontaneously hypertensive rat. (1992) (14)
Effects of calcium antagonists on the secretion of atrial natriuretic peptide in normal volunteers (1987) (14)
Anti-Oxidant Gene Therapy by NFkB Decoy Oligodeoxynucleotide (2006) (13)
Influence of coronary risk factors on coronary events in Japanese high-risk hypertensive patients. - Primary and secondary prevention of ischemic heart disease in a subanalysis of the Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) trial-. (2011) (13)
Effects of ipragliflozin, a selective sodium–glucose co-transporter 2 inhibitor, on blood pressure in Japanese patients with type 2 diabetes mellitus: a pooled analysis of six randomized, placebo-controlled clinical trials (2015) (13)
Hepatocyte nuclear factor-1a gene and non-insulin-dependent diabetes mellitus in the Japanese population (1998) (13)
Association of distal chromosome 2q with IDDM in Japanese subjects (1998) (13)
Direct evidence of elevated levels of circulating platelet-activating factor in a patient with disseminated intravascular coagulation syndrome. (1989) (13)
Circulating Levels of Calcitonin Gene-Related Peptide in Patients with Medullary Thyroid Carcinoma (1989) (13)
Quantitative measurement of neurological deficit after mild (30 min) transient middle cerebral artery occlusion in rats (2007) (13)
Vascular smooth muscle maintains the levels of Bcl-2 in endothelial cells. (2001) (13)
Impairment of collateral formation in Lp(a) transgenic mice : Therapeutic angiogenesis induced by human hepatocyte growth factor (HGF) gene (2002) (13)
Association of CTG repeats and the 1-kbAlu insertion/deletion polymorphism at the myotonin protein kinase gene in the Japanese population suggests a common Eurasian origin of the myotonic dystrophy mutation (1996) (13)
Leukemia developing after 131I treatment for thyroid cancer in a patient with Werner's syndrome: molecular and cytogenetic studies. (1995) (13)
Clinical evaluation of hypokalemia in anorexia nervosa. (1989) (13)
Molecular Nature of Aldosterone Synthase, a Member of Cytochrome P-45011β Family (1991) (13)
[Congenital adrenal hypoplasia]. (1993) (13)
Blood pressure response to an angiotensin II antagonist in patients with acromegaly. (1979) (12)
Expression of Histocompatibility Antigen HLA‐DR on the Epithelial Cells of the Pancreatic Duct and Thyroid Follicle An Autopsy Case (1990) (12)
Effects of weight loss on renal function in overweight Japanese men (2011) (12)
Insulin-dependent diabetes mellitus associated with autoimmune thyroiditis and rheumatoid arthritis. (1997) (12)
Does gene therapy become pharmacotherapy? (2005) (12)
Metabolic effects of long-term treatments with nifedipine-retard and captopril in young hypertensive patients. (1997) (12)
Isolation and mapping of microsatellites from a library microdissected from the Werner syndrome region, 8p11.2–p22 (1993) (12)
The clinical efficacy and tolerability of the angiotensin II-receptor antagonist losartan in Japanese patients with hypertension. (1996) (12)
Sequence Analysis of Tnf as a Candidate for Idd16 (2002) (12)
HMG-Co A reductase inhibitors in the treatment of cardiovascular diseases: stabilization of coronary artery plaque. (2002) (12)
Promoter Polymorphism of RGS2 Gene Is Associated with Change of Blood Pressure in Subjects with Antihypertensive Treatment: The Azelnidipine and Temocapril in Hypertensive Patients with Type 2 Diabetes Study (2010) (12)
Hormonal mechanisms in blood pressure reduction during hemodialysis in patients with chronic renal failure. (1995) (12)
Lys418Asn Polymorphism of the α2-Adrenoceptor Gene Relates to Serum Uric Acid Levels But Not to Insulin Sensitivity (2005) (12)
Association of polymorphism in the promoter region of the apolipoprotein E gene with diastolic blood pressure in normotensive Japanese. (2000) (12)
Activated T cells induce up-regulation of Fas antigen in cultured endothelial cells. (1997) (12)
Influence of adrenomedullin 2/intermedin gene polymorphism on blood pressure, renal function and silent cerebrovascular lesions in Japanese: the Ohasama study (2011) (12)
Exaggerated natri-calci-uresis and increased circulating levels of parathyroid hormone and 1,25-dihydroxyvitamin D in patients with senile hypertension. (1991) (12)
Effect of long-term treatment with antihypertensive drugs on quality of life of elderly patients with hypertension: a double-blind comparative study between a calcium antagonist and a diuretic. NICS-EH Study Group. National Intervention Cooperative Study in Elderly Hypertensives. (2000) (12)
Pulmonary venous flow and risk of cardiovascular disease in essential hypertension (2008) (12)
A novel gene-transfer technique mediated by HVJ (Sendai virus), nuclear protein, and liposomes. (1994) (12)
Elevated amyloid beta protein(1-40) level induces CREB phosphorylation at serine-133 via p44/42 MAP kinase (Erk1/2)-dependent pathway in rat pheochromocytoma PC12 cells. (1997) (11)
Continuous infusion of angiotensin II modulates hypertrophic differentiation and apoptosis of chondrocytes in cartilage formation in a fracture model mouse (2015) (11)
Renal Protective Effect in Hypertensive Patients: The High Doses of Angiotensin II Receptor Blocker (HARB) Study (2007) (11)
Long-term effects of candesartan and amlodipine on cardiovascular mortality and morbidity in Japanese high-risk hypertensive patients: rationale, design, and characteristics of candesartan antihypertensive survival evaluation in Japan extension (CASE-J Ex). (2009) (11)
Six dinucleotide repeat polymorphisms on chromosome 7 (1994) (11)
DISCREPANCY BETWEEN RENIN mRNA AND PLASMA RENIN LEVEL IN ANGIOTENSIN‐CONVERTING ENZYME INHIBITOR‐TREATED RATS (1993) (11)
Insulin receptor gene polymorphism and hyperinsulinemia in hypertensive patients. (1995) (11)
Trandolapril Review of its Pharmacodynamic and Pharmacokinetic Properties, and Therapeutic Use in Essential Hypertension (1994) (11)
Clinical Efficacy of Carvedilol in Severe Hypertension (1991) (11)
MEDULLARY CARCINOMA OF THE THYROID WITH ECTOPIC ACTH SYNDROME (1982) (11)
Aspirin prevents adhesion of T lymphoblasts to vascular smooth muscle cells (2007) (11)
Participation of both intracellular free Ca2+ and protein kinase C in tonic vasoconstriction induced by prostaglandin F2 alpha. (1990) (11)
Evidence for Cd101 but not Fcgr1 as candidate for type 1 diabetes locus, Idd10. (2005) (11)
Do reduced insulin sensitivity and dyslipidemia exist in borderline hypertensive patients? (1994) (11)
Akt activation prevents Apop-1-induced death of cells. (2008) (11)
N141I mutant presenilin-2 gene enhances neuronal cell death and decreases bcl-2 expression. (2002) (11)
Antisense Cdk2 kinase oligodeoxynucleotide inhibits ICAM-1 expression in murine cardiac allograft arteriopathy. (1998) (11)
A promoter polymorphism of lamin A/C gene is an independent genetic predisposition to arterial stiffness in a Japanese general population (the Tanno and Sobetsu study). (2009) (10)
P-556: β2- and β3-adrenoceptor polymorphisms are related with weight gain and blood pressure elevation over 5 years (2005) (10)
Plasma levels and renal clearance of two isomers of dopamine sulfate in patients with essential hypertension. (1988) (10)
Common genetic basis between type 1 and type 2 diabetes mellitus indicated by interview-based assessment of family history. (2004) (10)
Effects of antihypertensive treatment on cardiac hypertrophy and cardiac function in elderly hypertensive patients. (1991) (10)
Improvement of liver function parameters in patients with type 2 diabetes treated with thiazolidinediones. (2005) (10)
Changes in the levels of plasma atrial natriuretic peptide, hemodynamic measurements, and the levels of vasoactive hormones during the clinical course of congestive heart failure (1988) (10)
A simplified Radioimmunoassay for serum aldosterone (1977) (10)
Antihypertensive efficacy of FK906, a novel human renin inhibitor. (1993) (10)
Genetic association between chromosome 8 microsatellite (MS8-134) and Werner syndrome (WRN): chromosome microdissection and homozygosity mapping. (1995) (10)
Genetic Dissection of Type 1 Diabetes Susceptibility Gene, Idd3, by Ancestral Haplotype Congenic Mapping (2002) (10)
Plasma inactive renin in diabetic patients with neuropathy: a role for the sympathetic nervous system in the conversion in vivo of inactive renin. (1983) (10)
Conditioned medium from HepG2 cells transfected with human apolipoprotein(a) gene stimulates growth of human vascular smooth muscle cells: effects of overexpression of human apolipoprotein(a) gene. (1998) (10)
Improvement of organ damage by a non-depressor dose of imidapril in diabetic spontaneously hypertensive rats. (2007) (10)
Effects of a benidipine-based combination therapy on the risk of stroke according to stroke subtype: the COPE trial (2013) (10)
EDTA induces differentiation and suppresses proliferation of promyelocytic leukemia cell line HL-60--possible participation of zinc. (1992) (10)
Evaluation of hypotensive mechanisms of captopril in addition to its inhibition of the converting enzyme in spontaneously hypertensive rats. (1982) (9)
[Drug compliance in the elderly]. (1992) (9)
Angiotensin converting enzyme inhibitors suppress the vascular renin-angiotensin system of spontaneously hypertensive rats. (1991) (9)
Calcitonin prevents CCl4-induced hydroperoxide generation and cytotoxicity possibly through C1b receptor in rat hepatocytes. (1996) (9)
Dinucleotide repeat polymorphism at the D8S1053 (1994) (9)
Vasoconstriction and Hypersensitivity to Vasoactive Substances After Acute Volume Expansion in Dogs (1988) (9)
[Upregulation of angiotensin-converting enzyme during the healing process after injury at the site of percutaneous transluminal coronary angioplasty in humans]. (1998) (9)
Release of prostaglandin I2 from hog kidney by propranolol. (1982) (9)
Rapid ventricular pacing can reduce heart motion and facilitate stent deployment to the optimal position during coronary artery stenting: initial experience. (2007) (9)
Molecular cloning and expression of cDNAS encoding rat aldosterone synthase: variants of cytochrome P-450(11 beta). (1990) (9)
alpha 1-Antichymotrypsin as a risk modifier for late-onset Alzheimer's disease in Japanese apolipoprotein E epsilon 4 allele carriers. (1997) (9)
T 1 31 C Polymorphism of Angiotensinogen Gene and Essential Hypertension (2001) (9)
Rationale, study design and implementation of the COLM study: the combination of OLMesartan and calcium channel blocker or diuretic in high-risk elderly hypertensive patients (2009) (9)
Regression of left ventricular hypertrophy by angiotensin converting enzyme inhibitor in reduced renal mass hypertensive rats. (1991) (9)
Gap junction protein locus on chromosome 18 cosegregates with body weight in the spontaneously hypertensive rat. (1995) (9)
[Angiotensin II type 2 receptor gene]. (2006) (9)
Effect of ipriflavone on bone mineral density and calcium-related factors in elderly females (2005) (9)
Effect of captopril on renal vascular resistance, renin, prostaglandins and kinin in the isolated perfused kidney. (1983) (9)
Effect of reactive hyperemia after coronary recanalization on myocardial tissue reperfusion by thrombolysis in myocardial infarction flow grade in acute myocardial infarction. (2006) (9)
A calcium‐channel blocker, benidipine, improves forearm reactive hyperemia in patients with essential hypertension (2005) (9)
Role of HLA class II alleles in Korean patients with IDDM. (1996) (9)
Actions of endothelin on adrenergic neuroeffector junction. (1989) (9)
Increased Release of Platelet-Derived Growth Factor from Platelets in Chronic Liver Disease (1994) (9)
Questionnaire survey on the Japanese guidelines for treatment of hypertension in the elderly: 1999 revised version. (2002) (9)
Low density lipoprotein and apoprotein B induce increases in inositol trisphosphate and cytosolic free Ca2+ via pertussis toxin-sensitive GTP-binding protein in vascular smooth muscle cells. (1989) (9)
Polymorphism of HSP70 gene is not associated with type 1 (insulin-dependent) diabetes mellitus in Japanese. (1993) (9)
Contribution of the activation of the ras oncogene to the evolution of aldosterone- and renin-secreting tumors. (1991) (9)
Impairment of Instantaneous Autonomic Regulation Relates to Blood Pressure Fall Immediately after Standing in the Elderly and Hypertensives (2006) (9)
Partial DiGeorge syndrome at the age of thirty-four. (1994) (8)
Impact of concomitant diabetes and chronic kidney disease on preload-induced changes in left ventricular diastolic filling in hypertensive patients (2011) (8)
Association between hepatocyte growth factor gene polymorphism and essential hypertension. (2004) (8)
Comparative effects of monatepil, a novel calcium antagonist with alpha 1-adrenergic-blocking activity, and nitrendipine on lipoprotein and carbohydrate metabolism in patients with hypertension. (1994) (8)
The efficacy and long-term safety of a triple combination of 80 mg telmisartan, 5 mg amlodipine and 12.5 mg hydrochlorothiazide in Japanese patients with essential hypertension: a randomized, double-blind study with open-label extension (2016) (8)
Narrowing the position of the Werner syndrome locus by homozygosity analysis-extension of homozygosity analysis. (1996) (8)
α-Adrenergic Blocking Action of 1-O-Hexadecyl-2-0-Acetyl-sn-Glycero-3-Phosphocholine in Rats (1983) (8)
Plasma inactive renin in patients with hyperthyroidism. (1983) (8)
[Therapeutic policy for elderly hypertensives in Japan--a questionnaire survey of specialists]. (1994) (8)
Comparison of effects of estriol on bone mineral density of vertebrae between elderly and postmenopausal women (1998) (8)
Therapeutic potential of decoy oligonucleotides strategy in cardiovascular diseases (2003) (8)
Congenic mapping and functional analysis of a second component of the MHC-linked diabetogenic gene (Idd16) (2000) (8)
Polymorphism in gene for islet autoantigen, IA-2, and type 1 diabetes in Japanese subjects. (2001) (8)
Mapping and promoter sequencing of HNF-1beta gene in diabetes-prone and -resistant mice. (2001) (8)
Effects of candesartan and amlodipine on cardiovascular events in hypertensive patients with chronic kidney disease: subanalysis of the CASE-J study (2009) (8)
Angiotensin-converting-enzyme genotype and ischemic heart disease. (1995) (8)
Participation of decreased serum cholesteryl ester transfer activity, independent of increased serum lipoprotein(a), in angina pectoris in normolipemic elderly subjects. (1992) (8)
Levels of plasma 6-keto-PGF1 alpha in normotensive and essential hypertensive males with and without a family history of hypertension. (1983) (8)
Downregulation of endothelin expression in allograft coronary arteries after gene therapy targeting Cdk2 kinase. (1998) (8)
Effects of the baroreceptor reflex system on atrial natriuretic factor secretion during volume expansion in dogs. (1989) (8)
[Measurement of plasma renin activity by angiotension I radioimmunoassay]. (1973) (8)
Association between fatty acid binding protein 3 gene variants and essential hypertension in humans. (2008) (8)
Hypertension in a patient with Gitelman's syndrome (2004) (8)
Contribution of cardiovascular hypersensitivity to orthostatic hypertension and the extreme dipper phenomenon. (2000) (8)
Mapping the genetic diversity of HLA haplotypes in the Japanese populations (2015) (8)
Effects of cardiac complications on cardiovascular events in Japanese high-risk hypertensive patients: subanalysis of the CASE-J trial. (2009) (8)
[Genetic polymorphisms of the renin-angiotensin system]. (2001) (8)
Effect of aging on 6-keto-PGF1 alpha levels in normotensive and essential hypertensive males. (1983) (7)
Early-onset type 2 (non-insulin-dependent) diabetes mellitus is associated with glucokinase locus, but not with adenosine deaminase locus, in the Japanese population. (1994) (7)
Molecular and epidemiological studies of Werner syndrome in the Japanese population (1997) (7)
Hypertension and genes (2001) (7)
P-121: UCSNP-43 G/A polymorphism of calpain-10 gene is associated with hypertension and dyslipidemia in Japanese population (2003) (7)
Consistent activation of prorenin mRNA in renal hypertensive rats. (1991) (7)
Enzyme immunoassay for cortisol in serum using cortisol 21-amine. (1978) (7)
in Human Endothelial Cells Hydrogen Peroxide Induces Up-Regulation of Fas (1998) (7)
Hypotensive mechanism of potassium supplementation in salt-loaded patients with essential hypertension. (1985) (7)
Association of SLC6A9 gene variants with human essential hypertension. (2009) (7)
Effect of nifedipine on endothelial function in normotensive smokers: potential contribution of increase in circulating hepatocyte growth factor (2004) (7)
Transfection of Antisense p 53 Tumor Suppressor Gene Oligodeoxynucleotides Into Rat Carotid Artery Results in Abnormal Growth of Vascular Smooth Muscle Cells (2000) (7)
Enzyme immunoassay for serum 18-hydroxycorticosterone and its clinical application (1984) (7)
High degree of mitochondrial 3243 mutation in gastric biopsy specimen in a patient with MELAS and diabetes complicated by marked gastrointestinal abnormalities. (2003) (7)
Effect of prostacyclin infusion on active and inactive renin release in the isolated perfused kidney. (1982) (7)
Asp905Tyr polymorphism of protein phosphatase 1 G subunit gene in hypertension. (1997) (7)
Symposium on the etiology of hypertension--summarizing studies in 20th century. 1. Hypertension and genes. (2001) (7)
RENAL INTERACTION OF ATRIAL NATRIURETIC PEPTIDE WITH ANGIOTENSIN II: GLOMERULAR AND TUBULAR EFFECTS (1989) (7)
Effect of atrial natriuretic peptide on catecholamine release from human pheochromocytoma. (1989) (7)
Extra-adrenal pheochromocytoma manifesting renovascular hypertension. (1987) (7)
Novel strategy of gene therapy in cardiovascular disease with HVJ-liposome method. (1996) (7)
Evaluation of the efficacy and tolerability of combination therapy with candesartan cilexetil and amlodipine besilate compared with candesartan cilexetil monotherapy and amlodipine besilate monotherapy in Japanese patients with mild-to-moderate essential hypertension: a multicenter, 12-week, randomi (2012) (7)
Augmentation by converting enzyme inhibition of accelerated endothelin release from rat mesenteric arteries following nephrectomy. (1994) (7)
Parathyroid Hormone–Related Protein Upregulates Interleukin-1β–Induced Nitric Oxide Synthesis (1997) (7)
Identification of genes regulated by glucose in a pancreatic beta-cell line by a new method for subtraction of mRNA (1996) (7)
Development of new screening system for Alzheimer disease, in vitro Aβ sink assay, to identify the dissociation of soluble Aβ from fibrils (2006) (7)
The locus for Japanese myotonic dystrophy is also linked to D19S19 on the long arm of chromosome 19. (1990) (7)
Clinical efficacy and tolerability of candesartan cilexetil (1999) (7)
Evaluation of the renin-angiotensin system in diabetes insipidus and psychogenic polydipsia. (1982) (7)
Effects of valinomycin on calcium mobilization in vascular smooth muscle cells induced by angiotensin II. (1989) (7)
[Determination of plasma renin activity using gammer coat [125I] PRA kit (author's transl)]. (1980) (7)
Blood pressure response to an angiotensin II antagonist in thyrotoxic patients with and without high blood pressure. (1980) (7)
Effects of calcium channel blocker benidipine-based combination therapy on target blood pressure control and cardiovascular outcome: a sub-analysis of the COPE trial (2016) (7)
Effects of calcium channel blocker benidipine-based combination therapy on target blood pressure control and cardiovascular outcome: a sub-analysis of the COPE trial (2016) (7)
Rationale for time-qualified reference standards for 24-hour blood pressure values and their circadian rhythms in Japanese normotensive adults: a study by the Ambulatory Blood Pressure Monitoring Research Group. (1999) (6)
[Clinical heterogeneity in elderly patients with diabetes mellitus]. (2002) (6)
Influence of aging on progression of cardiovascular complications associated with insulin resistance in patients with essential hypertension. (1997) (6)
Cellular mechanism of glyburide-induced insulin gene expression in isolated rat islets. (1993) (6)
Comparison of the biological effects of two angiotensin II analogues in hypertensive patients with sodium depletion. (1978) (6)
Effects of prostaglandin F2 alpha on the mobilization of cytosolic free calcium in vascular smooth muscle cells and on the tension of aortic strips from rats. (1990) (6)
Direct vascular effects of 19-hydroxyandrostenedione. (1989) (6)
Glyburide enhances insulin gene expression and glucose-induced insulin release in isolated rat islets. (1994) (6)
Differential regulation of brain angiotensin II in genetically hypertensive and normotensive rats after nephrectomy. (1994) (6)
Enzyme immunoassay of serum testosterone. (1977) (6)
Role of Angiotensin II in the Renal Response to Atrial Natriuretic Peptide in Normal Subjects (1988) (6)
Carrier detection of Werner's syndrome using a microsatellite that exhibits linkage disequilibrium with the Werner's syndrome locus (1994) (6)
Development of novel method of non-viral efficient gene transfer into neonatal cardiac myocytes. (2005) (6)
Vascular effects and metabolism of angiotensins and their metabolites in the isolated perfused rat kidney. (1983) (6)
Design and Baseline Characteristics of an Observational Study in Japanese Patients with Hypertension: Japan Hypertension Evaluation with Angiotensin II Antagonist Losartan Therapy (J-HEALTH) (2007) (6)
Increases in circulating level of platelet-activating factor lag behind transient neutropenia during hemodialysis with cuprophane membranes. (1991) (6)
Exercise-induced electrocardiographic changes in patients with chronic respiratory diseases: differential diagnosis by 99mTc-tetrofosmin SPECT. (2003) (6)
Is normoreninemic essential hypertension caused by disordered central dopaminergic regulation? (1980) (6)
Electric Field Exposure Improves Subjective Symptoms Related to Sleeplessness in College Students: A Pilot Study of Electric Field Therapy for Sleep Disorder (2017) (6)
[Genetic analysis of candidate gene polymorphisms in elderly hypertension]. (1999) (6)
Sequence analysis of candidate genes for common susceptibility to type 1 and type 2 diabetes in mice. (2001) (6)
[Cushing's syndrome found during long-term glucocorticoid treatment of rheumatoid arthritis in an elderly woman]. (1992) (6)
Changes in the plasma hANP level during long-term salt loading in patient with essential hypertension. (1988) (6)
Association of angiotensin‐I converting enzyme DD genotype with influenza pneumonia in the elderly (2002) (6)
Gly40Ser mutation of glucagon receptor gene and essential hypertension in Japanese. (1996) (6)
Development of a Geriatric Prognostic Scoring System for Predicting Survival After Surgery for Elderly Patients With Gastrointestinal Cancer (2019) (6)
Kartagener's syndrome associated with infundibular pulmonic stenosis, chronic renal failure and azoospermia: a report of a case. (1986) (6)
[Quality of life in the pharmacologically treated elderly patients]. (1999) (6)
[Glucose tolerance and insulin resistance in the elderly]. (1997) (6)
Clinical Efficacy of a New Angiotensin II Type 1 Receptor Blocker, Pratosartan, in Hypertensive Patients (2008) (6)
Central and peripheral effects of dopamine on the renin-angiotensin-aldosterone system in conscious rats. (1981) (6)
Pancreatic Cell–speciﬁc Expression of Thioredoxin, an Antioxidative and Antiapoptotic Protein, Prevents Autoimmune and Streptozotocin-induced Diabetes (1998) (6)
Molecular cloning and sequence analysis of cDNA encoding rat adrenal cytochrome P-450(11)beta. (1989) (6)
Evaluation of Morning Blood Pressure Elevation and Autonomic Nervous Activity in Hypertensive Patients Using Wavelet Transform of Heart Rate Variability (2006) (6)
How to use marginal structural models in randomized trials to estimate the natural direct and indirect effects of therapies mediated by causal intermediates (2011) (6)
Usefulness of the beta-blocker carteolol and its effect on quality of life elderly hypertensive patients (1991) (6)
Reserpine, hydrochlorothiazide and pituitary-gonadal hormones in hypertensive patients (1980) (6)
Phase I study of a new orally active angiotensin-I-converting enzyme inhibitor, delapril (1987) (5)
Effect of hydrochlorothiazide in addition to telmisartan/amlodipine combination for treating hypertensive patients uncontrolled with telmisartan/amlodipine: a randomized, double-blind study (2016) (5)
Injection of HGF Plasmid cDNA to Prevent Manifestation of Parkinson Disease: A Preclinical Study using a Primate Model (2009) (5)
[Glucose transporter gene]. (1997) (5)
Idd1 and Idd3 are necessary but not sufficient for development of type 1 diabetes in NOD mouse. (2004) (5)
EFFECTS OF CHRONIC CONVERTING ENZYME INHIBITION ON THE VASCULAR RENIN‐ANGIOTENSIN SYSTEM (1990) (5)
Anti-oxidant gene therapy by NF kappa B decoy oligodeoxynucleotide. (2006) (5)
High blood pressure worsens age‐related increases in arterial stiffness evaluated by pulse wave velocity in subjects with lifestyle‐related diseases (2007) (5)
Elastase enhances cAMP accumulation and the inhibition of DNA synthesis induced by OP-41483, a stable prostacyclin analogue, in vascular smooth muscle cells. (1994) (5)
Urinary Catecholamine Response to Glucagon in Young and Elderly Patients with Essential Hypertension † (1980) (5)
Genetics of Hypertension and Cardiovascular Disease (2011) (5)
Association of SLC 6 A 9 Gene Variants with Human Essential Hypertension (2007) (5)
Hypertension in the Elderly (2011) (5)
Age- and HLA-dependent heterogeneity in the association of a marker on chromosome 2q with insulin-dependent diabetes mellitus (1996) (5)
3.P.283 Inhibition of growth of human aortic vascular smooth muscle cells by a phosphodiesterase type 3 inhibitor, cilostazol, through p53-mediated apoptosis (1997) (5)
Effects of 1,25-dihydroxyvitamin D3 on the syntheses of DNA and glycosaminoglycans by rat aortic smooth muscle cells in vitro. (1990) (5)
Role of protein kinase C in the regulation of glucagon gene expression by arginine. (1990) (5)
[Risk factors related to the wall thickness of carotid artery assessed by ultrasonography]. (1994) (5)
MHC‐Linked Susceptibility to Type 1 Diabetes in the NOD Mouse (2005) (5)
[A case of primary aldosteronism with polycystic kidney disease]. (1986) (5)
Therapeutic Angiogenesis in Peripheral Arterial Disease and Cardiovascular Disease : Introduced by Transfection of Hepatocyte Growth Factor Gene (2003) (5)
The effects of temocapril, a new angiotensin converting enzyme inhibitor, on the quality of life in hypertensive patients (1992) (5)
[Gene therapy for arteriosclerotic diseases]. (2001) (5)
Arterial pulse wave velocity in elderly patients with dementia (2002) (5)
Endothelin modulates L-NG-nitroarginine-induced enhancement of vasoconstriction evoked by norepinephrine. (1991) (5)
Increased plasma level of endothelin with vasoconstriction after dextran infusion. (1990) (5)
Effect of enalapril treatment on the quality of life of elderly patients with essential hypertension with complications (1989) (5)
Fas Ligand mRNA Levels of Circulating Leukocytes Reflect Endothelial Dysfunction in Hyperlipidemic but Not in Non-Hyperlipidemic Patients (2006) (5)
Molecular genetics of insulin-dependent diabetes mellitus: Analysis of congenic strains (1996) (5)
[Angiotensinogen gene polymorphism]. (2006) (4)
Catheter-delivered in vivo gene transfer into rat myocardium using the fusigenic liposomal mediated method. (2000) (4)
The effect of 5 alpha-dihydrocortisol on the blood pressure of rats treated with deoxycorticosterone acetate and salt. (1980) (4)
Hepatocyte growth factor (HGF) angiogenic gene therapy: promises for cardiovascular diseases (2001) (4)
Characteristics of dynamic mutation in Japanese myotonic dystrophy (1994) (4)
Adverse reactions to lipiodol ultra fluid: report of an accidental case. (1991) (4)
Insulin Resistance and the Renin-Angiotensin-Aldosterone System in Metabolic Syndrome and Obesity-Related Hypertension (2010) (4)
Therapeutic approach to familial hypercholesterolemia by HVJ-liposomes in LDL receptor knockout mouse. (2002) (4)
[Abnormalities in acid-base balance in the elderly]. (1992) (4)
The worldwide controversy about the polymorphism of the vitamin D receptor gene and bone mineral density. (2000) (4)
Apolipoprotein E-deficient mice created by systemic administration of antisense oligodeoxynucleotides: a new model for lipoprotein metabolism studies. (2002) (4)
Effects of an Angiotensin II Antagonist;[Sarcosine1, Isoleucine8] Angiotensin II, on Blood Pressure, Plasma Renin Activity and Plasma Aldosterone Concentration in Hypertensive and Normotensive Subjects Taking Oral Contraceptives (1979) (4)
[Primary biliary cirrhosis with polymyositis successfully treated with prednisolone and ursodeoxycholic acid]. (1996) (4)
Decreased serum 19-nor-deoxycorticosterone (21-hydroxy-19-nor-4-pregnene-3, 20-dione) level in adrenal regeneration hypertensive rats (1983) (4)
A high-density STS map based on a single contig of YAC and P1 clones in the chromosome 8p12-p21 region. (1997) (4)
A Second Component of HLA‐Linked Susceptibility to Type 1 Diabetes Maps to Class I Region (2005) (4)
Association between senescence‐related uncoupling protein 2 gene polymorphisms and abdominal obesity in Japanese subjects: The Tanno and Sobetsu study (2006) (4)
Effect of ticlopidine on PDGF release from platelets (1992) (4)
[Potassium channel opener]. (2000) (4)
A Case of Pseudomyxoma Peritonei with Bilateral Pleural Metastases (1982) (4)
Effect of alacepril on quality of life in the treatment of hypertension (1991) (4)
[A case of Hashimoto's thyroiditis associated with renal tubular acidosis, Sjögren syndrome and empty sella syndrome]. (1992) (4)
Changes in plasma atrial natriuretic polypeptide concentration during head-out water immersion and saline infusion in normal men. (1987) (4)
Effect of long-term treatment with delapril on quality of life in hypertensive patients (1992) (4)
[Urinary bacteria in elderly patients with urinary incontinence and low levels of daily activity]. (1997) (4)
A family with von Hippel-Lindau disease revealed by pheochromocytoma. (2001) (4)
Analysis of the apolipoprotein B3' hypervariable region in patients with essential hypertension. (1992) (4)
Linkage and haplotype analysis of familial early-onset Alzheimer disease in Japanese population (1995) (4)
Bradykinin suppresses endothelin-induced contraction of coronary, renal and femoral arteries through its B2-receptor on the endothelium. (1992) (4)
ANG II inhibits insulin-mediated production of PI 3,4,5-trisphosphates via a Ca2+-dependent but PKC-independent pathway in the cardiomyocytes. (2010) (4)
In vivo evaluation of in vitro hypothesis using "gain or loss" of function: functional analysis of renin-angiotensin system. (1998) (4)
Changes of blood pressure, plasma renin activity and plasma aldosterone concentration following the infusion of Sar1-Ile8-angiotensin II in hypertensive, fluid and electrolyte disorders. (1976) (4)
[Role of angiotensin in the metabolic syndrome and cardiovascular complications]. (2002) (4)
Molecular Scanning of the Gene for Programmed Cell Death‐1 (PDCD‐1) as a Candidate for Type 1 Diabetes Susceptibility (2005) (4)
Lack of association between the hepatocyte growth factor receptor, c-met, and the anti-apoptotic action of bag-1 in endothelial cells. (2004) (4)
Circulating suppressing factor for the muscarinic acetylcholine receptor in patients with senile dementia of the Alzheimer type. (1992) (4)
Effect of nilvadipine on quality of life in patients with essential hypertension (1992) (4)
A microsatellite polymorphism in the human insulin receptor gene: a highly informative marker for linkage analysis. (1993) (4)
Comparison of two angiotensin II analogues in normal subjects and hypertensive patients. (1978) (3)
[Genetic analysis of familial Alzheimer's disease]. (1991) (3)
[Morning blood pressure variability and autonomic nervous activity]. (2006) (3)
Quality of Life in the Treatment of Hypertension in the Elderly (1989) (3)
[Gene therapy for peripheral arterial diseases]. (2005) (3)
The role of antihypertensive polar renomedullary lipid in the pathogenesis of hypertension. (1984) (3)
Effects of frusemide and captopril on the relationship between biologically and immunologically active renin in human plasma. (1988) (3)
Gene therapy as a potential treatment for restenosis and myocardial infarction. (2000) (3)
Therapeutic Potential of Oligonucleotide-Based Therapy in Cardiovascular Disease (2012) (3)
Postpartum toxic shock syndrome: a report of a case. (1988) (3)
[Graves' disease with markedly elevated serum immunoglobulin E]. (1989) (3)
C7 Increased local vascular hepatocyte growth factor (HGF) in balloon injured arteries by an angiotensin converting enzyme inhibitor, cilazapril (1997) (3)
Multiple Endocrine Neoplasia Type 2b (I) Report of a Case (1980) (3)
[A simplified radioimmunoassay for serum aldosterone--non-extraction method with 125I-labeled aldosterone (author's transl)]. (1977) (3)
Renal vein prostaglandins in renovascular hypertensive patients. (1985) (3)
Renal effects of an angiotensin II antagonist in stroke-prone spontaneously hypertensive rat. (1997) (3)
[Guidelines for treatment of hypertension: JSH2004]. (2006) (3)
[Guidelines on treatment of hypertension in the elderly--1999 revised version. A comprehensive study on geriatric science by the Ministry of Health and Welfare. A Section for the "Study on Long-Term Prognosis of Hypertension among the Aged"]. (1999) (3)
Dinucleotide repeat polymorphism at the D8S1055 (1994) (3)
Current genetics of essential hypertension (2001) (3)
Subject Index Vol. 76,1997 (1997) (3)
Involvement of endogenous prostaglandins in salt-induced hypertension. (1985) (3)
Effects of Calcium-Channel Blocker Benidipine-Based Combination Therapy on Cardiac Events　- Subanalysis of the COPE Trial. (2017) (3)
Effect of vasodilator prostaglandins on the vascular renin-angiotensin system. (1988) (3)
Dietary salt, blood pressure and circulating levels of 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine in patients with essential hypertension. (1989) (3)
Identification of a single base polymorphism in intron 2 of the c-fos gene and its detection by mismatched PCR-RFLP (1994) (3)
[The renin-angiotensin system and blood pressure]. (1993) (3)
Dose-Effect Relationship of Carvedilol in Essential Hypertension (2012) (3)
Effects of ipragliflozin on left ventricular diastolic function in patients with type 2 diabetes and heart failure with preserved ejection fraction: The EXCEED randomized controlled multicenter study (2022) (3)
Impact of left ventricular hypertrophy on the time-course of renal function in hypertensive patients – a subanalysis of the CASE-J trial –. (2010) (3)
[Quality of life and the treatment of hypertension in the elderly]. (2007) (3)
Familial Bartter's syndrome. (1982) (3)
A model of cerebrovascular injury in rats (2008) (3)
Interleukin-2 Suppresses Endothelin-1 Secretion of Cultured Endothelial Cells (1992) (3)
Bradykinin suppresses endothelin-induced contraction of coronary artery through its B2-receptor on the endothelium. (1991) (3)
[Gene transfer with ultrasound and microbubbles (optison) as a potential treatment for cardiovascular diseases]. (2004) (3)
[A case of normoreninemic normotensive primary aldosteronism associated with nephrocalcinosis (author's transl)]. (1982) (3)
Direct renal action of captopril (SQ 14225): dissociation of natriuretic and vascular actions in isolated perfused rat kidney. (1982) (3)
[Susceptibility genes for type 1 diabetes]. (2002) (3)
Blood pressure response to [1-sarcosine, 8-isoleucine] angiotensin II in patients with liver cirrhosis and ascites. (1979) (3)
Functional analysis of cardiovascular renin-angiotensin system using a gain or loss of function approach. (2000) (3)
Present state of diabetes management in the elderly, Japan. (2007) (3)
[Antihypertensive treatment guideline for elderly hypertension]. (2001) (3)
[Renin gene analysis of familial Bartter's syndrome]. (1992) (3)
Activated angiotensin II generation and regulation in rat mesenteric arteries following nephrectomy. (1994) (3)
Contents of dopamine sulfoconjugate isomers and their desulfation in dog arteries. (1989) (3)
P-548: Which is more effective on weight loss-induced blood pressure reduction, a low caloric diet or an aerobic exercise? (2001) (3)
Dinucleotide repeat polymorphism at D7S813. (1994) (3)
Parathyroid hormone-related protein upregulates interleukin-1beta-induced nitric oxide synthesis. (1997) (2)
Changes in sympathetic activity and insulin sensitivity during body weight reduction in obese subjects (1997) (2)
[Circadian changes of blood pressure in the elderly with Alzheimer's type dementia]. (1990) (2)
[Vascular endothelial cells and renin-angiotensin system]. (1998) (2)
[A case of severe systemic edema in an elderly hypertensive patient with systemic lupus erythematodes during long-term treatment with anti-hypertensive drugs]. (2001) (2)
Biphasic effects of interleukin-2 on proliferation of cultured vascular smooth muscle cells. (1992) (2)
Less frequent body weight gain in elderly type 2 diabetic patients treated with glimepiride (2003) (2)
177 EFFECTS OF WEIGHT LOSS ON LIVER FUNCTION IN OBESE HYPERTENSIVE PATIENTS (2012) (2)
[Plasma norepinephrine variation with dietary sodium intake in normotensive subjects and patients with essential hypertension]. (1982) (2)
Intracellular signal transduction evoked by low-density lipoprotein in vascular smooth muscle cells. (1991) (2)
The action of low density lipoprotein on vascular smooth muscle cells involves increase in intracellular pH. (1990) (2)
Hyperparathyroidism as a cause of calcification of the abdominal aorta in elderly female subjects (1996) (2)
Relationships of Beta2- and Beta3--Adrenoceptor Polymorphisms with Obesity, Hypertension and Metabolic Syndrome (2010) (2)
Potential gene therapy for glomerulonephritis: Transfection of NFKB decoy inhibited TNF-A induced cytokine and adhesion molecules expression in vivo (1996) (2)
Therapeutic angiogenesis induced by HGF: Potential gene therapy for ischemic diseases (2000) (2)
Different changes of bone mineral density and nutritional status after hospitalization between vascular dementia and Alzheimer's disease in elderly female patients (2007) (2)
CLINICAL APPLICATION OF ANGIOTENSIN II ANALOGUE (III). CHANGES OF BP, PRA AND PAC FOLLOWING SAR^1 ILE^8 A-II INFUSION : IIIrd Auditorium : PROCEEDINGS OF THE 40TH ANNUAL MEETING OF THE JAPANESE CIRCULATION SOCIETY (1976) (2)
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Pharmacological study of alacepril, an angiotensin I-converting enzyme inhibitor, in healthy volunteers (1987) (2)
[Physiological and pathological aging and electrolyte metabolism]. (1991) (2)
[Clinical implications of ultrasonic tissue characterization for atherosclerotic carotid intima-media]. (2000) (2)
IS081 TRANSCRIPTION FACTOR DECOY FOR NF_KB INHIBITS TNF-α INDUCED EXPRESSIONS OF IL-6 AND ICAM IN ENDOTHELIAL CELLS (1997) (2)
[Acute lymphoblastic leukemia accompanied by severe hypercalcemia; successful treatment with bisphosphonate]. (1995) (2)
Comparisons of maltase activities in kidney brush border membranes from normal, diabetic, glucose-infused and maltose-infused rabbits. (1989) (2)
Mapping of 20 polymorphic DNA markers in the rat by somatic hybrid and linkage analysis (2009) (2)
Increased atrial natriuretic factor secretion after endothelin injection in dogs. (1990) (2)
Dinucleotide repeat polymorphism at the D8S1223 locus (1996) (2)
Polymorphism of TNFB gene is associated with specific HLA alleles, but not with insulin-dependent diabetes mellitus in Japanese population (1996) (2)
Sensitive direct radio-immunoassay for human renin. (1984) (2)
[Levels of plasma 6-keto-PGF1 alpha in normotensive and essential hypertensive males with and without a family history of hypertension and effects of aging]. (1982) (2)
A case of renovascular hypertension with marked polyuria after percutaneous transluminal renal angioplasty. (1996) (2)
Detection of Pstl RFLP in human ADA by the polymerase chain reaction (1991) (2)
B3 - Role of insulin resistance in cardiovascular hypertrophy in patients with essential hypertension (1995) (2)
Genetic risk factors for cerebral infarction using data from a large‐scale genetic epidemiological study: the Ohasama Study (2003) (2)
[Evaluation by specialists of the Guidelines on Treatment of Hypertension in the Elderly--the second questionnaire survey]. (1997) (2)
[Gene loci and polymorphisms of angiotensin II receptor]. (1999) (2)
Gene therapy for ischemic brain disease with special reference to vascular dementia (2007) (2)
Sensitive assay and kinetic property of urinary inhibitor of Na+, K+-ATPase in sodium-loaded patients with essential hypertension. (1985) (2)
Effect of two years of enalapril treatment on the quality of life of ederly patients with essential hypertension complicated by other diseases (1990) (2)
[Case of Rendu-Osler disease associated with a giant hematoma of the mesocolon and renovascular hypertension caused by thrombosis]. (1983) (2)
Selective Pharmacological Effects of Triprolyl and Pentasarcosyl Angiotensin II (1987) (2)
Stimulatory effect of 1,25-dihydroxyvitamin D3 on transferrin synthesis in primary cultures of adult rat hepatocytes. (1990) (2)
In Vivo Evidence of Enhancement of HGF-induced Angiogenesis by Fluvastatin (2008) (2)
Metabolism of bradykinin in isolated perfused rat kidney. Measurement of kininase activity in perfusate and urine. (1986) (2)
Analysis of a variable number of tandem repeats in a heart disease gene by capillary electrophoresis with laser-induced fluorescence detector. (1998) (2)
Contribution of the Baroreflex Afferent Nerves to the Production of Vasoconstricted Hypertension in Volume-Expanded Dogs (1989) (2)
Glomerular nodular lesions in non-amyloid immunoglobulin deposition disease: their pathogenetic relationship to mesangiolysis. (1994) (2)
Proteolytic activation of aldosterone biosynthesis in rabbit adrenal capsular cells by alpha-chymotrypsin. (1989) (2)
Disparate cardiovascular responses to passive tilt and mental stress in young and elderly normotensives. (1991) (2)
Prevention and regression of atopic dermatitis by ointment containing NFkB decoy oligodeoxynucleotides in NC/Nga atopic mice model (2002) (2)
Cytosine-adenine repeat polymorphism at calcitonin gene locus associated with serum osteocalcin level in Japanese women. (2006) (2)
Effect of the calcium antagonist nicardipine on the pressor action of endothelin. (1990) (2)
[Multicenter prospective survey of prognosis of hypertensive elderly outpatient under antihypertensive treatment--morbidity and mortality of cardiovascular diseases and cancer]. (1999) (2)
[Enzyme immunoassay of steroid hormones]. (1982) (2)
Initial appearance of an ill-defined shadow on a chest roentgenogram in a patient with aortitis syndrome. (1991) (2)
Identification of 19-nor-deoxycorticosterone in normal rat serum by enzyme immunoassay and gas chromatography-mass spectrometry. (1984) (2)
The effect of age on active and cryoactivatable inactive plasma renin in normal subjects and patients with essential hypertension. (1981) (2)
Effect of cyclosporin A on aldosterone production by dispersed rabbit adreno-capsular cells. (1990) (2)
[The effect on age for the relationship between hypertension and glucose intolerance]. (1993) (2)
[A case of mild-type myotonic dystrophy with dementia and severe arteriosclerosis obliterans]. (1998) (2)
Urinary C-peptide as an index of unstable glycemic control in insulin-dependent diabetes mellitus (IDDM) (1991) (2)
Stimulatory effect of lipoprotein (a) on proliferation of human mesangial cells: role of lipoprotein (a) in renal disease. (1998) (2)
Platelet-activating factor and anti-platelet-aggregating factor in acute reduction of blood pressure following percutaneous transluminal renal angioplasty in patients with renovascular hypertension. (1988) (2)
Pharmacodynamics and pharmacokinetics of a new orally active angiotensin-I-converting enzyme inhibitor, alacepril (DU-1219), in normal subjects and hypertensive patients (1987) (2)
[Radioimmunoassay of plasma aldosterone and its clinical application]. (1973) (2)
[Two cases of Werner's syndrome treated with penetrating keratoplasty]. (1993) (2)
[Diabetic complications and their features in the elderly]. (2006) (2)
Inflammation and Salt Sensitivity in the Early State of Hypertension (2007) (2)
Enzyme immunoassay of corticosterone. (1979) (2)
[Enzyme immunoassay for serum 18-hydroxycorticosterone and its clinical application]. (1985) (2)
Prevention of cardiac allograft arteriopathy by antisense Cdc2 kinase oligonucleotide. (1999) (2)
[Glycated serum protein (GSP), glycated albumin (GA) and fructosamine]. (2002) (1)
The long-term safety of BIBR277 (Telmisartan), the long-acting angiotensin II AT1 receptor antagonist, in patients with mild-to-moderate essential hypertension (2002) (1)
1.P.118 Novel gene therapy strategy for atherosclerosis using ribozyme against apolipoprotein (a) gene (1997) (1)
Analysis of tissue renin angiotensin system by “gain” or “loss” of function approach (1997) (1)
[Effects of pravastatin administration for 12 months on serum lipid levels in aged patients with hypercholesterolemia]. (1994) (1)
[An analysis of questionnaires about geriatric medicine/medical education sent to members of the Japanese Society of General Medicine]. (1999) (1)
Interaction between the vascular renin‐angiotensin system and prostaglandins (1988) (1)
Clinical Trial of Human Gene Therapy Using Hepatocyte Growth Factor Gene Transfer(Translational Research in Cardiovascular Disease, The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (1)
Earlier management of subjects who are prone to hypertension and diabetes mellitus (2004) (1)
[Molecular genetics of myotonic dystrophy]. (1995) (1)
[Hemorrhagic colon ulcer as a side effect of non-steroidal anti-inflammatory drugs in five aged patients]. (1997) (1)
P-434: Uric acid level is one of the predictors of BP elevation and obesity (2002) (1)
[Hypertension and vascular remodeling]. (2001) (1)
[Characteristics and management of hypertension in the elderly]. (1993) (1)
[Glycated serum protein (GSP) glycated albumin (GA) and fructosamine]. (1998) (1)
[Comparison of hypotensive effects of acutely administered human parathyroid hormone (1-34) in normal young and elderly subjects]. (1989) (1)
PE-444 C-Reactive Protein in Essential Hypertension : Association with Left Ventricular Mass Index and Risk of Cardiovascular Disease(Hypertension, clinical-04, The 71st Annual Scientific Meeting of the Japanese Circulation Society) (2007) (1)
Effect of three angiotensin II antagonists, [Sar1, Thr8]-, [Sar1, Ile8]-and [Sar1, Ala8]angiotensin II on blood pressure and endocrine factors in normal subjects (2004) (1)
[Renin-dependent hypertension in a case with a giant renal artery aneurysm (author's transl)]. (1981) (1)
[Mechanisms of hypertensive complications modified by tissue RAAS]. (2009) (1)
[Effect of aging on blood catecholamine under 3 conditions of sodium intake--comparison between normal subjects and patients with essential hypertension]. (1983) (1)
[An autopsied case of a 45-year-old man with Hutchinson-Gilford progeria syndrome]. (1986) (1)
Preventing effect of angiotensin-1 converting enzyme inhibitors on pneumonia in elderly subjects (1998) (1)
[Genes in rennin-angiotensin system]. (2004) (1)
[Effect of aging on urinary kallikrein excretion in normal subjects and patients with essential hypertension (author's transl)]. (1981) (1)
Contribution of Class III MHC to Susceptibility to Type 1 Diabetes in the NOD Mouse (2005) (1)
L13 A family history of hypertension and sympathetic nerve hyperactivity are predictors of blood pressure elevation(BP-E) in normotensive subjects (1997) (1)
Central sodium loading modifies norepinephrine content in the ventrolateral medulla and blood pressure in rats. (1988) (1)
Relation between low serum cholesteryl-ester transfer activity and abdominal aortic calcification in normolipidemic elderly subjects. (1993) (1)
Long-term effects of pravastatin on serum lipid levels in elderly patients with hypercholesterolemia. (1994) (1)
INHIBITION OF NEOINTIMAL FORMATION BY BERAPROST SODIUM (BPS) IN THE PORCINE CORONARY ARTERY AFTER BALLOON INJURY: P 306 (2004) (1)
Effect on the combination of BIBR277 (Telmisartan), the long-acting angiotensin II AT1 receptor antagonist, with calucium antagonists or diuretics in patients with mild-to-moderate essential hypertension (2002) (1)
Detection of PstI RFLP in human ADA by the polymerase chain reaction. (1991) (1)
[Genetic analysis of common disease]. (1997) (1)
[The usefulness of a new class antihypertensive drug, angiotensin II receptor antagonist, for essential hypertension]. (1999) (1)
[Gene therapy in congestive heart failure]. (2005) (1)
Neurovascular Role of Sympathetic Nervous System and Beta-Adrenoceptor Polymorphisms in Obesity and Hypertension (2008) (1)
Nicorandil is a potent dilator of endothelin-induced vascular contraction. (1990) (1)
A case of SLE with calcinosis universalis and basal ganglia calcification (1992) (1)
Evidence against DNA polymerase β as a candidate gene for Werner syndrome (1994) (1)
Potentiation of the pressor effect of angiotensin II by intraventricular infusion of hypertonic saline. (1988) (1)
Clinical application of an angiotensin II analogue (III) (1976) (1)
841 OPTIMAL BLOOD PRESSURE TO PREVENT CARDIOVASCULAR EVENTS IN THE ELDERLY HIGH-RISK HYPERTENSIVE PATIENTS: SUBANALYSIS OF THE CASE-J EX STUDY (2012) (1)
[Susceptibility genes for IDDM]. (1997) (1)
Renin-Angiotensin-Aldosterone System Renin-Angiotensin Inhibition Reverses Advanced Cardiac Remodeling in Aging Spontaneously Hypertensive Rats (2007) (1)
[A case with non-Hodgkin lymphoma manifesting chylothorax and chylous ascites]. (1986) (1)
[A new medical treatment for thrombosis by genetic engineering]. (1999) (1)
E019: Hypertension characterizes impairment of coronary flow reserve in patients with diabetes (2000) (1)
Effect of elastase in reversing the de-differentiation of rabbit costal chondrocytes in culture induced by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate (TPA). (1991) (1)
[Calcium antagonists and endothelial function]. (2005) (1)
Sympathetic hyperactivity plays an important role in blood pressme elevation in obese normotensives (1998) (1)
Effects of a Specific Angiotensin II Receptor Antagonist on the Vascular Renin-Angiotensin System in Spontaneously Hypertensive Rats (1993) (1)
O-54: Oxidative stress inhibits insulin signal transduction in cultured human vascular smooth muscle cells: A possible contribution to mechanism of insulin resistance (2001) (1)
Parathyroid hormone-related protein inhibits indothelin-1 production. (1996) (1)
[Angiotensin receptor antagonist for therapy of patients with hypertension]. (1997) (1)
Three dinucleotide repeat polymorphisms at the D8S1217, D8S1220, and D8S1221 loci (1995) (1)
Abstract P131: The Effects of Weight Loss on Liver Function in Obese Hypertensive Patients (2012) (1)
L48 Association of polymorphism in critical core promoter element of angiotensinogen gene with increased risk of essential hypertension (1997) (1)
P-581: The role of endothelin-1 produced by insulin in the regulation of cell growth and renin-angiotensin system in endothelial cells (2001) (1)
Effect of aging on the renin angiotensin system in patients with renovascular hypertension. (1992) (1)
MOLECULAR SCANNING OF THE HUMAN IL-21 GENE AND ASSOCIATION STUDY WITH TYPE 1 DIABETES (2005) (1)
[Pharmacological effects of HMG-CoA reductase inhibitors]. (2002) (1)
[Genetic basis of arterial calcification for diabetes mellitus]. (2003) (1)
[Affected siblings with Alzheimer's disease had missense mutation of codon 717 in amyloid precursor protein gene]. (1992) (1)
IS028 GENE THERAPY OF RESTENOSIS BY IN VIVO GENE TRANSFER OF HUMAN HEPATOCYTE GROWTH FACTOR (HGF) THROUGH THE ACCELATION OF RE-ENDOTHELIALIZATION (1998) (1)
In vitro study on the effects of bradykinin potentiating factor and angiotensin II analogue on degradation and conversion of angiotensin I and II in plasma. (1974) (1)
Abstract 2406: C-Reactive Protein in Essential Hypertension: Association with Left Ventricular Mass Index and Risk of Cardiovascular Disease (2006) (1)
Antisense Cdc2 kinase oligonucleotide inhibits adhesion molecule expression in cardiac allograft arteriopathy. (1999) (1)
Relation of Serum Parathyroid Hormone to Cognitive Function in Elderly Females (1989) (1)
Importance of the sympathetic nervous system in blood pressure elevation by subpressor intraventricular NaCl and angiotensin II in the rat. (1991) (1)
Effects of two angiotensin II analogues on blood pressure, plasma aldosterone concentration, plasma renin activity and creatinine clearance in normal subjects on different sodium intakes (1980) (1)
[A simple solid phase radioimmunoassay for plasma renin activity (author's transl)]. (1981) (1)
[Hypertension in the elderly]. (2004) (1)
Analysis of glucokinase locus as a candidate for shared genetic susceptibility between NIDDM and IDDM (1997) (1)
Synergic effects of kallikrein-kinin and prostaglandins on renin release on infusion of isolated hog kidney with aldosterone. (1984) (1)
Comparison of the production of cyclic AMP in response to parathyroid hormone in fibroblasts from aged subjects and young subjects: lack of an age-dependent decrease. (1990) (1)
Mitogenic and Anti-Apoptotic Actions of Hepatocyte Growth Factor Through Erk, Stat3 and Akt in Human Aortic Endothelial Cells (2000) (1)
Oligonucleotide-based molecular therapy for restenosis after angioplasty. (2003) (1)
[Therapeutic drug monitoring of alpha-blocker, prazosin]. (1990) (1)
Molecular nature of aldosterone synthase, a member of cytochrome P-450(11 beta) family. (1991) (1)
Clinical efficacy and safety of lisinopril (MK-521) in the treatment of hypertension in patients with renoparenchymal disease or impaired renal function (1990) (1)
EFFECTS OF CALCIUM CHANNEL BLOCKER BENIDIPINE-BASED COMBINATION THERAPY ON CARDIAC EVENTS: SUB-ANALYSIS OF THE COPE TRIAL (2014) (1)
Changes of Blood Pressure, Renin and Aldosterone Secretions by Angiotensin II (1977) (1)
[Gene therapy for myocardial regeneration]. (2003) (1)
4 On-going Japanese Clinical Trials for Hypertension II : Seeking for More Effective Pharmacological Treatment(ESC-JCS Joint Symposium (ESC-JCS Joint Symposium) (H) Evidence-Based Medical Treatment of Hypertension,Special Program,The 72nd Annual Scientific Meeting of the Japanese Circulation Society (2008) (1)
Hepatocyte Growth Factor (2007) (1)
G17: The relation between insulin resistance and isolated systolic hypertension in elderly patients (1997) (1)
Efficacy and safety of a new calcium antagonist AJ-2615 in essential hypertension (1992) (1)
Sustained transgene expression by transfection of renin gene into liver of neonates. (1996) (1)
Studies on the role of platelet-activating factor in blood pressure regulation (1991) (1)
Lack of association between hepatocyte nuclear factor-1beta gene and common forms of type 2 diabetes in the Japanese population. (2001) (1)
[A simplified direct radioimmunoassay for urinary aldosterone (author's transl)]. (1979) (1)
[A case of recessive dystrophic epidermolysis bullosa associated with dwarfism with special reference to pathophysiological role of growth hormone]. (1990) (1)
[Clinical application of adrenoceptor blockers in the treatment of hypertension]. (1989) (0)
3WS16-1 Mechanical stress-related atherosclerosis and functional genomics (2003) (0)
Effect of volume expansion on hemodynamic variables in nephrectomized dogs (2004) (0)
BARTTER'S SYNDROME, A CASE REPORT AND SOME CONSIDERATION ON PATHOGENETIC MECHANISM (1974) (0)
[Genetic analysis of Werner syndrome in a family]. (1995) (0)
INHIBITION OF NEOINTIMAL FORMATION AND INCREASED LOCAL VASCULAR HEPATOCYTE GROWTH FACTOR (HGF) PRODUCTION IN BALLOON INJUREDARTERIFSBY ANGIOTENSIN CONVERTING ENZYME INHIBITOR (1997) (0)
Gene therapy for preventing delayed neuronal death using hepatocyte growth factor (2002) (0)
Insulin receptor substrate-1 gene polymorphism in type 2 diabetes mellitus and essential hypertension : Association study and meta-analysis (2000) (0)
[Characteristic and therapy of hypertension in the aged]. (1996) (0)
Hypertensive RatsProduced byInVivo Introduction oftheHumanReninGene (1993) (0)
ANTI-APOPTIC EFFECTS OF HEPATOCYTE GROWTH FACTOR IMPROVE HEART FUNCTION AND MORTALITY AGAINST DOXORUBICIN-INDUCED HEART FAILURE: P 652 (2004) (0)
Topical application of the NF-kB-dummies for the treatment of atopic dermatitis (2002) (0)
Therapeutic Angiogenesis Induced by Endotherial Nitric Oxide Synthase Gene through VEGF Expression in Rat Hindlimb Ischemia Model (2003) (0)
A highly polymorphic dinucleotide repeat at the D8S1222 locus (1995) (0)
[Current state and perspective of studies on hypertensive complications]. (2004) (0)
Probucol prevents the progression of diabetic complications: Five-year follow-up study (1993) (0)
[Diabetes mellitus in the elderly]. (1999) (0)
[Acute adrenocortical insufficiency]. (1993) (0)
Blood pressure changes following chronic administration to rats of 3beta,16beta-dihydroxy-5-androsten-17-one, 3beta,17beta-dihydroxy-5-androsten-16-one and 21-hydroxy-4-pregnene-3,20-dione-21-acetate. (1977) (0)
[Gene therapy for restenosis after angioplasty]. (1997) (0)
[Genes and hypertension]. (2000) (0)
P010: Obesity, sympathetic hyperactivity, insulin resistance and hyperleptinemia are related with blood pressure level (1998) (0)
[Hypertension of the aged]. (2007) (0)
Hyperreninemia and hypertension observed during Kaufmann therapy of patients with gonadal dysgenesis and hypopituitarism. (1989) (0)
43) Effects of Angiotensin-Converting Enzyme Inhibitors on Blood Pressure, the Renin-Angiotensin System and Heart Weight in Spontaneously Hypertensive Rat (2008) (0)
Anal ysis of Candidate Genes for Insulin in Essential Hypertension Resistance (2006) (0)
391 BETA2-ADRENOCEPTOR POLYMORPHISMS (ARG16GLY) IS RELATED TO RESISTANCE TO WEIGHT LOSS INDUCED IMPROVEMENTS OF CARDIAC- AND RENAL COMPLICATIONS (2012) (0)
Bone mineral density in a rat model of non-insulin dependent diabetes mellitus (1997) (0)
[A case of hyperinsulinemia due to hypersecretion of incretin]. (1992) (0)
Abstract 5094: OSBPL10 is Identified as a Novel Susceptible Gene for Peripheral Arterial Disease by Genome-Wide Association Study in Japan (2008) (0)
Positive Association Between the Lys198 Asn Polymorphism in the Endothelin-1 and Blood Pressure in Obese Japanese Subjects: Ohasama Study (2000) (0)
[Gene polymorphisms and cardiovascular diseases in the elderly]. (1999) (0)
Contents, Supplement 1, 1990 (1990) (0)
48 Variety of presenilin-1 mutations in japanese familial early-onset Alzheimer's disease (1996) (0)
The Role of Endothelial Cells in the Insulin-Mediated Vascular Cell Proliferation (2002) (0)
RENAL PROTECTIVE EFFECT OF STRONG SUPPRESSION OF RENIN ANGIOTENSIN SYSTEM IN HYPERTENSIVE PATIENTS - HIGH DOSE OF ARB WITH ACE INHIBITOR STUDY (HAWAII) STUDY: PP.15.69 (2010) (0)
Association studies on human chromosome 1p22 and insulin-dependent diabetes mellitus (1998) (0)
[Biochemistry of renin]. (1984) (0)
IS060 ARole of Insulin Like Growth Factor-I in the Progression of Vascular Hypertrophy (2000) (0)
WHICH TREATMENT IS THE BEST WAY FOR OBESE HYPERTENSIVE PATIENTS WITH HYPERURICEMIA?: P 763 (2004) (0)
PGE2, 6-O-PGF1α and sodium balance in essential hypertensive patients (1984) (0)
Gene Therapy for Peripheral Arterial Occlusive Diseases (PAOD) (2002) (0)
P708 FREQUENCY OF DEVELOPMENT OF ESTABLISHED HYPERTENSION FROM THE BORDERLINE HYPERTENSIVES IN A 10-YEAR PERIOD IN JAPANESE MEN (1996) (0)
[Clinical characteristic of elderly patients with insulin-dependent diabetes mellitus]. (1992) (0)
Contribution of Adiponectin Gene Mutation to Coronary Artery Disease (2003) (0)
Contribution of elevated peripheral resistance to acute volume loaded hypertension in dogs. (1987) (0)
AGE‐RELATED DIFFERENCES IN THE EFFECTS OF ANTIHYPERTENSIVE THERAPY ON LEFT VENTRICULAR HYPERTROPHY IN HIGH‐RISK PATIENTS WITH HYPERTENSION—CANDESARTAN ANTIHYPERTENSIVE SURVIVAL EVALUATION IN JAPAN SUBANALYSIS (2011) (0)
P-503: Comparisons between genetic influence of hypertension and environmental factors on blood pressure level (2003) (0)
ENHANCED THERAPEUTIC ANGIOGENESIS BY CO-TRANSFECTION OF PROSTACYCLIN SYNTHASE GENE: P 435 (2004) (0)
[Bartter's syndrome, a case report and some consideration on pathogenetic mechanism (author's transl)]. (1974) (0)
Therapeutic Angiogenesis Induced by Transfection of Hepatocyte Growth Factor (HGF) Gene in Porcine Myocardial Infarction Model (2003) (0)
[Review of randomized trials of angiotensin receptor blockers in the treatment of patients with congestive heart failure]. (2001) (0)
338 TYPE 2 DIABETES MELLITUS AND RESIDUAL CARDIOVASCULAR RISK IN HIGH-RISK HYPERTENSIVE PATIENTS: A SUBANALYSIS OF THE CASE-J EXTENSION (2012) (0)
[Studies on plasma renin activity measurement as routine laboratory analysis (author's transl)]. (1977) (0)
Nitric oxide and Hypoxia Induce Up-regulation of Fas in Human Vascular Smooth Muscle Cells (1997) (0)
[Werner's syndrome and familial Alzheimer's disease]. (1993) (0)
PJ-175 Tissue Inhibitor of Metalloproteinase-3-deficiency Prevents Hypertension Induced by Nitric Oxide Synthase Inhibition(Hypertension, Basic 2 (H) : PJ30)(Poster Session (Japanese)) (2004) (0)
PJ-090 Therapeutic angiogenesis by a transcription factor : Ets-1 for peripheral arterial disease(Gene Therapy 1 (IHD) : PJ15)(Poster Session (Japanese)) (2004) (0)
[Primary-and secondary aldosteronism and electrolyte (author's transl)]. (1974) (0)
3.P.220 Prevention of high glucose-induced endothelial cell death by phosphodiesterase type 3 (PDE3) inhibitor through activation of local hepatocyte growth factor (HGF) production (1997) (0)
FAMILY HISTORY OF OBESITY AND FAMILY HISTORY OF HYPERTENSION CONTRIBUTE TO BP ELEVATION IN A LONGITUDINAL STUDY OF 2 YEARS: P2.93 (2000) (0)
Role of vascular angiotensin generating system and mechanical stress in the vascular remodeling (1994) (0)
[Probable toxic shock syndrome following pleural drainage]. (2004) (0)
Insulin Receptor Hyperinsulinemia Gene Polymorphism and in Hypertensive Patients (2006) (0)
Possible participation of the central histaminergic system in pressor responses to intracerebroventricular injection of hypertronic saline in rats (1990) (0)
[Ectopic ACTH-producing syndrome]. (1978) (0)
Expression of regulated endocrine-specific protein (RESP) 18 gene in mouse insulinoma cell line and various mouse endocrine tissues (1995) (0)
[Angiogenic therapy for acute coronary syndrome]. (2004) (0)
The Tet-On system in transgenic mice Tissue-specific and doxycycline-inducible inhibition of the retinoid X receptor in pancreatic beta cells (2003) (0)
CLINICAL USEFULNESS AND LIMITATION OF BRACHIAL-ANKLE PULSE WAVE VELOCITY TO EVALUATE CARDIOVASCULAR COMPLICATIONS IN PATIENTS WITH ESSENTIAL HYPERTENSION: P 470 (2004) (0)
[How far should a physician go in correcting patients' life-style? (Con)]. (2006) (0)
Plasma levels of inflammatory related substances are correlated with severity of aortic stiffness and endothelial dysfunction in hypertensive patients (2002) (0)
Effects of an Antihypertensive Combination in Japanese Hypertensive Outpatients Based on the Long-Acting Calcium Channel Blocker Benidipine on Vascular and Renal Events: A Sub-Analysis of the COPE Trial. (2020) (0)
AGE-RELATED DIFFERENCES IN THE EFFECTS OF CANDESARTAN AND AMLODIPINE ON LEFT VENTRICULAR HYPERTROPHY IN HIGH RISK HYPERTENSIVE PATIENTS - CASE-J SUB-ANALYSIS: PP.27.83 (2010) (0)
[Pituitary hypertension]. (1992) (0)
Epidemiology and CKD - 2 (2009) (0)
Effects of weight loss on serum uric acid (2012) (0)
[Effect of antihypertensive treatment in elderly hypertensive patients with cardiac hypertrophy]. (1992) (0)
Genetic epidemiology of hypertension and cerebrovascular disease (2002) (0)
A drug that contains hgf gen (1996) (0)
Effect of α-glucosidase inhibitor voglibose on postprandial hyperglycemia in patients with IDDM and NIDDM treated with insulin (1997) (0)
1P-0253 Eicosapentaenoic acid promotes endothelial cell survival through upregulation of the cellular FLICE-inhibitory protein (2003) (0)
Novel Therapeutic Strategy for Restenosis Using Ribozyme Oligonucleotides Against Transforming Growth Factor-β (2000) (0)
Evaluation of utility of prostagrandin E1 in the patients with ASO : Protective effect on endothelial function through up-regulation of HGF (2002) (0)
[Mineralocorticoid activity and effect on blood pressure of synthetic 16beta-OH-dehydroepiandrosterone and 16-oxoandrostenediol in rats (author's transl)]. (1977) (0)
Abstract 3934: Gene-Environment Interaction Regarding Ethanol Metabolizing Enzymes in the Japanese General Population (2006) (0)
Abstract 3628: Serum Macrophage Inflammatory Protein 1 Beta as a Predictor for Cerebro-Cardiovascular Events in Hypertensive Patients (2006) (0)
[Recent multi-center clinical studies about calcium blockade and cardiovascular diseases]. (2006) (0)
MECHANISMS IN OBESITY HYPERTENSION IN ACUTE-ONSET AND CHRONIC-ONSET OBESE HYPERTENSIVES: P2.148 (2000) (0)
Regulation of Vascular Smooth Muscle Cells Growth: -Toward to Gene Therapy-@@@―遺伝子治療に向けて― (1996) (0)
OJ-248 Losartan Reduced Massive Proteinuria in Chronic Renal Disease Patients with Lower Renal Tissue TGF-beta1 mRNA Levels(Hypertension, Clinical 5 (H) : OJ29)(Oral Presentation (Japanese)) (2004) (0)
PJ-752 A Novel Model of Vasculogenesis From ES Cells for Vascular Research and Regenerative Medicine(Development and differentiation-4 (M) PJ129,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society) (2006) (0)
[Principle for treatment of hypertension]. (2011) (0)
OJ-529 Ribozyme Oligonucleotides Against TGF-Beta Transferred by Ultrasound Inhibited the Progression of Diseases in Anti-Thy1 Model(Kidney/Renal Circulation 3 (H) : OJ65)(Oral Presentation (Japanese)) (2004) (0)
[Dysuria in male elderly outpatients evaluated by a questionnaire survey]. (1992) (0)
[Management of water electrolyte imbalance in aged patients]. (2003) (0)
[Renin-angiotensin system and hypertension (author's transl)]. (1982) (0)
Gene therapy for diabetic ischemia (2000) (0)
[The renin-angiotensin system and insulin resistance]. (2005) (0)
Medicament comprenant le gene hgf (1996) (0)
Contribution of Angiotensin Converting Enzyme Gene Polymorphism to the Action of Angiotensin II Receptor Antagonist (CS-866) (2002) (0)
Cloning and Functional Analysis of a Novel Gene Expressed in Atherosclerotic Plaques (2003) (0)
D070: Prognosis of elderly hypertensive patients in Japan (1999) (0)
Hypoxia stimulates the release of the soluble form of Fas ligand and inhibits hypoxia-induced apoptosis in endothelial cells (2000) (0)
IS026 Hypoxia Induced Endothelial Apoptosis Through the Activation of NFkB : In Vivo Evidence of Importance of NFkb in Endothelial Cell Regulation (2000) (0)
216 EFFECTS OF WEIGHT LOSS ON SERUM URIC ACID (2012) (0)
A comparison of biological effects of three angiotensin II antagonists in sodium depleted hypertensive patients. (1983) (0)
[Serotoninergic receptor antagonist]. (2000) (0)
Development of Novel High Throughput Functional Screening System Based on HVJ-E Vector : Screening of Anti-vascular Remodeling Factor in Hypertension(Hypertension, Basic 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (0)
P-573: Mechanisms in weight loss program, but not significant weight loss, -induced blood pressure reduction (2001) (0)
[A case of systemic lupus erythematosus with severe neutropenia and the effect of high dose globulin therapy]. (1989) (0)
[Gene therapy for restenosis after angioplasty]. (1997) (0)
IS030 Prevention of Cardiac Allograft Arteriosclerosis with Single Intraluminal Delivery of Decoy to Transcription Factor E2F (1998) (0)
[Platelet-activating factor and antihypertensive polar renomedullary lipid: 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine]. (1982) (0)
P-156: E4 allele of apolipoprotein gene was associated with lower blood pressure (2001) (0)
Effect of ouabain on hemodynamics in acute volume expanded hypertensive dogs (1989) (0)
940. Ribozyme Oligonucleotides Against TGF-|[beta]| Transferred by Ultrasound Inhibited the Progression of Diseases in Anti-Thy1 Model (2004) (0)
Erratum to “Role of HLA class II alleles in Korean patients with IDDM” (1997) (0)
[Trends in hypertension research]. (2006) (0)
P-197: Synergistic effects of angiotensin converting enzyme and angiotensin II type 1 receptor gene polymorphisms on insulin resistance -the Tanno-Sobetsu study (2005) (0)
P009: Sympathetic activity is related with hyperinsulinemia and BP levels in a Japanese population (1998) (0)
[Pathophysiology of normotensive subjects with a family history of hypertension]. (1992) (0)
PI 3-kinase/Akt signaling controls endothelial cell sensitivity to Fas-mediated apoptosis via regulation of FLICE-inhibitory protein (FLIP) (2002) (0)
[Therapeutic angiogenesis by angiogenic growth factor]. (2003) (0)
A patient with DiGeorge syndrome at age of 30 years old (1991) (0)
Measurements of Enzyme Activity and Immunoreactivity of Plasma Renin. Limitations of the Conventional Method for Assay of Plasma Renin Catalytic Activity (1989) (0)
Association between PPAR γ polymorphism and hypertension in Japanese (2002) (0)
Effect of Angiotensin II on Differentiation and Apoptosis of Chondrocytes in Cartilage Formation in the Process of Fracture Healing (2015) (0)
Gene analysis of human hypertension (1994) (0)
[Congenital CBG deficiency]. (1993) (0)
The hypotensive effect of captopril is not mediated by renal medullary lipids. (1987) (0)
[Case of Al amyloidosis with severe orthostatic hypotension successfully treated by high-dose dexamethasone]. (2004) (0)
S15-04 Genetics of hypertension (2004) (0)
1174 CAPTOPRIL AND NIFEDIPINE-RETARD REDUCE THE PREVALENCE OF ORTHOSTATIC HYPOTENSION IN ELDERLY HYPERTENSIVE PATIENTS (1996) (0)
[Urinary catecholamine response to glucagon in young and elderly patients with essential hypertension (author's transl)]. (1980) (0)
PGE2, 6-O-PGF1 alpha and sodium balance in essential hypertensive patients. (1984) (0)
A BglII polymorphism for pKNB46 [D19S73]. (1990) (0)
E001: A family history of obesity, a family history of hypertension and blood pressure levels (2000) (0)
[Binding of steroid hormones and plasma proteins and the uptake of steroid hormones]. (1984) (0)
[Practice of gene therapy]. (2005) (0)
Accumulation of Exogenous Ouabain in Plasma and Organs and Systolic Blood Pressure Elevation in Spontaneously Hypertensive Rats (1995) (0)
P-685: Aortic calcification as a marker for arteriosclerosis obliterans of lower extremities in the elderly (2001) (0)
Manidipine of its Use in the Management of Hypertension (2004) (0)
Gene Therapy for Myocardial Infarction (1998) (0)
Age-Dependence of Hypertensive (1983) (0)
239 α1-Antichymotrypsin gene as an independent risk for late-onset Alzheimer's disease (1996) (0)
WEIGHT GAIN INDUCED BP ELEVATION AND WEIGHT REDUCTION INDUCED BP REDUCTION: P1.20 (2000) (0)
Elevation of Serum Matrix Metalloprotease (MMP)-2 and Oxidant Stress in Patients with Acute Worsening of Chronic Heart Failure (2005) (0)
Overexpression of HGF (Hepatocyte Growth Factor) Reduced Ischemic Injury in Rat Permanent Middle Cerebral Artery Occlusion (MCAO) Model (2003) (0)
[Clinical application of peptides with inhibition of renin-angiotensin system (author's transl)]. (1980) (0)
[TNF gene polymorphism and IDDM]. (1997) (0)
Antihypertensive Treatment-Present and Future (1995) (0)
-0355-LOW DENSITY LIPOPROTEIN INCREASES INIERACELLULAR pH IN VASCULAR SMOOTH MUSCLE CELLS (1990) (0)
RELATION BETWEEN ACHIEVED BLOOD PRESSURE LEVEL AND THE REDUCTION OF CARDIOVASCULAR RISK IN HIGH-RISK HYPERTENSIVE PATIENTS: A SUBANALYSIS OF THE CASE-J TRIAL: PP.27.80 (2010) (0)
Editorial Genetics of Hypertension and Cardiovascular Disease (2010) (0)
[Roles of growth factors and cytokines in atherosclerosis]. (2001) (0)
D22 Gender differences in insulin sensitivity and sympathetic responsiveness in young hypertensives (1997) (0)
[Molecular genetic analysis of sporadic Alzheimer's disease]. (1993) (0)
Exaggerated calci- phospha-uresis to saline infusion in senile osteoporitic patients with low plasma renin activity (1990) (0)
Effect of E2F decoy on inhibitation of neointima formation in pig coronary arteries after balloon injury and stent implantation (2002) (0)
Calcitonin secretion in bedridden osteoporotic patients (1996) (0)
Long-Term Follow-Up Evaluation of Results From Clinical Trial ( TREAT-HGF ) Using Hepatocyte Growth Factor Gene to Treat Severe Peripheral Arterial Disease (2012) (0)
[Measurement and evaluation of renin-angiotensin system]. (2005) (0)
B29Differences in insulin(INS) resistance and dyslipdemia between the subjects with and without family history(FH) of hypertension(HT). (1995) (0)
Complications and the Choice of Antihypertensive Drugs in the Elderly (1989) (0)
[Two elderly cases of megacolon associated with cerebral infarction and diabetes mellitus]. (1993) (0)
S2-3 Toxicogenomics and pharmacogenomics at the Bedside (2001) (0)
[Studies on coagulation-fibrinolytic system in diabetic nephropathy--with reference to plasma TAT and alpha 2PIC]. (1990) (0)
Mechanical stress-related atherosclerosis and functional genomics (2004) (0)
Blood Pressure Measurement and Family History of Hypertension (2001) (0)
Additions and Corrections (2006) (0)
Systolic Blood Pressure and Baseline Perfusion Pressure and Pressor Responses to Periarteriai Nerve Stimulation and Exogenous Norepinephrine Injection in Isolated Perfused Mesenteric Arteries of Rats Variables Systolic blood pressure (2005) (0)
IS033 UP-REGULATION OF KEY TRANSCRIPTIONAL FACTOR FOR ANGIOGENESIS, ETS, AND INDUCTION OF ANGIOGENESIS BY IN VIVO GENE TRANSFER OF HUMAN HEPATOCYTE GROWTH FACTOR (HGF) INTO MYOCARDIUM (1998) (0)
H003: Different blood pressure regulatory mechanisms between obesity and hypertension (1998) (0)
Which strategy in inhibition of the renin-angiotensin system is the most efficient for heart failure? (2008) (0)
Advances in diagnosis and treatment for hypertension.3.Advances in treatment.4.Treatment for the elderly hypertension. (1995) (0)
Functional Analysis of Tissue Renin-Angiotensin System Using “Gain and Loss of Function” Approaches: In Vivo Test of in Vitro Hypothesis (1998) (0)
QuaIity of Life in the Treatment of Hypertension the Elderly (1989) (0)
[Effect of age on active and inactive plasma renin levels in normal subjects and in patients with essential hypertension (author's transl)]. (1980) (0)
[Management and treatment of elderly hypertension]. (2007) (0)
OJ-377 Combination Therapy by ACEI and ARB on vascular remodeling in a porcine coronary artery injury model(Restenosis after Angioplasty, Basic/Clinical 3 (IHD) : OJ46)(Oral Presentation (Japanese)) (2004) (0)
[Polymorphism in elderly hypertension]. (2005) (0)
Faculty Opinions recommendation of Ambulatory blood pressure monitoring after 1 year on valsartan or amlodipine-based treatment: a VALUE substudy. (2007) (0)
The role of gerontology in the era of a super-aged society. (2014) (0)
Impaired Endothelium-Dependent Vascular Relaxation in Fas-Lacking Mice (2003) (0)
DIFFERENT MECHANISMS IN WEIGHT LOSS INDUCED-BP FALL BETWEEN SHORT-TERM OBESITY AND LONG-TERM OBESITY: P2.120 (2000) (0)
G4: A new marker of hypertensive target organ damages: Serum level of Hepatocyte Growth Factor (HGF) (1997) (0)
[Perceived quality of life and social factors in elderly hypertensive patients]. (1995) (0)
-0794-ROLE OF ENDOTHELIN IN VASOCONSTRICTIVE BLOOD PRESSURE ELEVATION INDUCED BY ACUTE VOLUME EXPANSION IN DOGS (1990) (0)
A novel HMG-CoA reductase inhibitor, cerivastatin, suppresses MMP-1 and uPA activities in smooth muscle cells through ETS-1 (2000) (0)
552 COMBINATION THERAPY IN HYPERTENSION WITH CKD - A SUBANALYSIS OF COMBINATION THERAPY OF HYPERTENSION TO PREVENT CARDIOVASCULAR EVENTS (COPE) TRIAL (2012) (0)
Interleukin 15 is associated with cardiovascular complications in patients with essential hypertension (2004) (0)
PE-347 Association of Hypoadiponectinemia with Smoking Habit in Men(Diabetes/Obesity/Metabolic syndrome-6 (H) PE58,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society) (2006) (0)
-181-EFFECTS OF VALINOMYCIN ON CALCIUM MOBILIZATION IN VASCULAR SMOOTH MUSCLE CELLS INDUCED BY ANGIOTENSIN II : Cardiac Metabolism, Cardiac Biochemistry : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY (1989) (0)
Gene therapy for cardiovascular disease: Toward to clinical trial (2012) (0)
D009: Association of I/D polymorphyism of angiotensin-I-converting enzyme gene in postinfluenza pneumonia in elderly subjects (2000) (0)
The Prevention of Renal Injury Progression by Angiotensin Type 1 Receptor Antagonist (1993) (0)
-P120-CARDIOSTIMULATORY AND CARDIOSUPPRESSIVE ACTIONS OF INTRAVENOUSLY ADMINISTERED ENDOTHELIN : Hypertension : FREE COMMUNICATIONS(III) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY (1989) (0)
[Role of high blood pressure in progression of atherosclerosis in the metabolic syndrome]. (2006) (0)
Accumulation of exogenous Ouabain in plasma and organs in spontaneously hypertensive rats (1994) (0)
Age-related changes in the response of anterior pituitary hormones to human growth hormone releasing factor injection in normal subjects. (1988) (0)
CLINICAL APPLICATION OF ANGIOTENSIN II ANALOGUE : SYMPOSIUM III : Diagnosis and Treatment (1977) (0)
F2: Prevalence of hyperinsulinemia and sympathetic hyperactivity in young, non-obese, Japanese men (1997) (0)
STATINS ATTENUATE CARDIAC HYPERTROPHY THROUGH INHIBITION OF NOX2-CONTAINING NADPH OXIDASE: OP 115 (2004) (0)
[Pseudo-Bartter syndrome]. (1997) (0)
Analysis of the werner syndrome gene mutations (1997) (0)
FAMILY HISTORIES OF HYPERTENSION AND OBESITY ARE PREDICTORS OF HYPERURICEMIA: OP 006 (2004) (0)
[Intervention trials for elderly hypertension in Western countries]. (2005) (0)
53 Possible association between presenilin-1 locus and late-onset sporadic Alzheimer disease (1996) (0)
[Geriatric diseases and advanced medicine]. (2001) (0)
E001: Plasma leptin level does not play an important role on bp regulatory mechanisms in diabetes (2000) (0)
Gene Therapy to Treat Diabetic Neuropathy : Improvement of Diabetic Peripheral Neuropathy by HGF Gene and Prostacyclin Synthase Gene Transfer (2003) (0)
[Insulin, as a regulating factor of blood pressure]. (1997) (0)
Osteopontin stimulates Mitogen-activated Protein Kinases (MAPK) and Cell Growth through Activation of αvβ3 integrin in human endothelial cells (2000) (0)
[Effects of a single dose of captopril on blood pressure and the renin-angiotensin-aldosterone system in normal subjects and hypertensive patients with various etiologies (author's transl)]. (1979) (0)
Poster Session I: Epidemiology and public health (2010) (0)
CLINICAL RESULTS OF TREAT-HGF (JAPAN TRIAL TO TREAT PERIPHERAL ARTERIAL DISEASE BY THERAPEUTIC ANGIOGENESIS USING HEPATOCYTE GROWTH FACTOR GENE TRANSFER): P 531 (2003) (0)
ELEVATED SYMPATHETIC NERVOUS ACTIVITY IS RELATED TO THE DEVELOPMENT OF RENAL INJURY IN PATIENTS WITH DIABETES AND/OR HYPERTENSION: PP.30.189 (2010) (0)
Recent advances in clinical application of blockers of renin-angiotensin system. (1982) (0)
[Examination of genetic susceptibility for essential hypertension]. (2002) (0)
[Other genetically hypertensive rats]. (2000) (0)
A pepstatin-immunometric assay for active renin in human plasma. (1988) (0)
[Addison-Schilder's disease]. (1993) (0)
Spontaneous models for type 2 diabetes (2006) (0)
Polymorphism of myospryn is associated with left ventricular diastolic dysfunction (2008) (0)
The duration of obesity contributes to a resistance in weight loss program (2002) (0)
1P-0180 High glucose upregulates plasminogen activator inhibitor-1 (PAI-1) expression through activation of apoptosis signal-regulating kinase 1 (ASK1) in endothelial cells (2003) (0)
Downregulated Expression of the Soluble Form of Guanylate Cyclase in Vascular Smooth Muscle Cells Isolated from Fas-Lacking Mice (2003) (0)
IS048 VASCULAR ENDOTHELIAL GROWTH FACTOR RELEASED FROM VASCULAR SMOOTH MUSCLE CELLS PROTECT ENDOTHELIAL CELLS AGAINST NITRIC OXIDE-INDUCED CELL DEATH BY APOPTOSIS (1997) (0)
[The variation in the blood pressure of the patients with essential hypertension in summer and winter (author's transl)]. (1982) (0)
[Treatment of hypertension in the elderly]. (1995) (0)
[Genetic susceptibility to diabetes and hypertension]. (2003) (0)
OE-211 Differentiation of ES cells into sprouting vessels on Matrigel without growth factors(Angiogenesis 1 (M) : OE26)(Oral Presentation (English)) (2004) (0)
-1057-ENDOTHELIN ELEVATED Na^+/H^+ EXCHANGE IN VASCULAR SMOOTH MUSCLE CELLS : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY (1990) (0)
BETA1 (ARG389GLY, SER49GLY)- AND BETA2 (ARG16GLY)-ADRENOCEPTOR POLYMORPHISMS ARE RELATED TO LEFT VENTRICULAR HYPERTROPHY USING ECG IN MIDDLE-AGED, NORMOTENSIVE SUBJECTS: PP.22.358 (2010) (0)
Abnormal Gastrin Secretion in Diabetic Autonomic Neuropathy (1983) (0)
G15 Relation between endothelial dysfunction and early morning surge in blood pressure in patients with essential hypertension (1997) (0)
IS053 ANTI-APOPTOTIC ACTION OF HEPATOCYTE GROWTH FACTOR ON HUMAN AORTIC ENDOTHELIAL CELLS (1997) (0)
[Renomedullary hypotensive lipids and prostaglandins]. (1983) (0)
Calcium antagonist indirectly up-regulates superoxide dismutase expression in endothelial cells via vascular smooth muscle cell-dependent pathways (2002) (0)
DOES REDUCING HYPERURICEMIA REDUCE BLOOD PRESSURE IN HYPERTENSION WITH HYPERURICEMIA?: OP 160 (2004) (0)
[Characterisitics of Japanese Guidelines for the Management of Hypertension 2009]. (2011) (0)
Present and Future in the genetherapy for cardiovascnlardisease (1999) (0)
TOPICAL APPLICATION OF A NF-kB decoy FOR TREATING ATOPIC DERMATITIS (2002) (0)
Gene therapy for cerebral vascular diseases (2000) (0)
Effects of Carvedilol on Plasma Hormonal and Biochemical Factors and Renal Function in Japanese Patients with Essential Hypertension (1988) (0)
Soluble form of Fas ligand as a possible clinical marker for acute coronary syndrome (2002) (0)
FRS-013 Long Term Evaluation of Clinical Trial of Human Gene Therapy for Peripheral Arterial Disease Using Hepatocyte Growth Factor Gene Transfer(Angiogenesis and Regeneration Medicine in Cardiovascular Medicine (M) : FRS3)(Featured Research Session (English)) (2004) (0)
THE AUTONOMIC NERVOUS ACTIVITY EVALUATED BY 24 HOURS HOLTER ELECTROCARDIOGRAM WITH WAVELET ANALYSIS IS ASSOCIATED WITH FOREARM VASOREACTIVITY IN HYPERTENSIVE PATIENTS: P 416 (2004) (0)
, Hypoperfusion Model Gene Transfer of Hepatocyte Growth Factor to Subarachnoid Space in Cerebral (2002) (0)
4 Tailored Medicine for Hypertension and Cardiovascular Complications(Symposium 2 (SY2) (H) : Hypertension : From Molecular Mechanisms to Tailored Therapy)(Special Program) (2004) (0)
C36CAN DYSLIPIDEMIA AND REDUCED INSULIN (INS) RESISTANCE BE IMPROVED BY MEDICATIONS FOR HYPERTENSION? COMPARISON AMONG NIFEDIPINE (N), LACIDIPINE (L), CAPTOPRIL (C), AND TCV-114 (A NEW ANGIOTENSIN II RECEPTOR ANTAGONIST; T) (1995) (0)
Abstract 1351: Ubiquitin Carboxyl-Terminal Esterase L1, Causative Gene of Parkinson's Disease, Modulates Anti-Inflammatory-Mediated Vascular Remodeling (2006) (0)
[Treatment of hypertension and quality of life in the elderly]. (1992) (0)
OR 44: Genetic influences of β adrenergic receptors polymorphisms on aortic stiffness and left ventricular hypertrophy in patients with essential hypertension (2004) (0)
Increase in the blood pressure and decrease in the norepinephrine release in the ventrolateral medulla during intraventricular administration of hypertonic NaCl (1989) (0)
Hemodynamic Alterations Following Infusion of Angiotensin II Analogue in Normal Subjects (1977) (0)
Relationship between Gene Polymorphism and Plasma Dopamine β-Hydroxylase Activity in Hypertensive and Normotensive Subjects (1994) (0)
[An elderly case of hypertension with persistent orthostatic hypotension]. (1992) (0)
Effects of the creation of arteriovenous shunt for hemodialysis on cardiac function and natriuretic peptide levels in chronic renal failure (2002) (0)
[The long term effects of the oral converting enzyme inhibitor, captopril in hypertensive patients--the endocrinological study of its hypotensive mechanism (author's transl)]. (1980) (0)
DIFFERENT MECHANISMS IN WEIGHT LOSS-INDUCED BLOOD PRESSURE REDUCTION BETWEEN A CALORIC RESTRICTED DIET AND EXERCISE: PP.9.242 (2011) (0)
Hepatocyte growth factor specifies hemotopoitic mesoderm in Xenopus embryos (2002) (0)
Diabetes Diabetic Hind Limb Ischemia Model : Molecular Mechanisms of Delayed Angiogenesis in Therapeutic Angiogenesis Induced by Human Hepatocyte Growth Factor Gene in Rat (2001) (0)
The role of the renin-angiotensin system in plaque rupture of coronary artery (1998) (0)
Association of a Sodium Channel (cid:1) Subunit Promoter Variant with Blood Pressure (2001) (0)
Guidelines for Hypertension in the 1999 Revised Version-Elderly (2006) (0)
Hepatocyte Growth Factor ( HGF ) as a Potential of Severity of Hypertension Index (2006) (0)
Erratum to “Role of HLA class II alleles in Korean patients with IDDM”: Diabetes Res. Clin. Pract. 31 (1996) 9–15 (1996) (0)
Two dinucleotide repeat polymorphisms at the D8S1218 and D8S1219 loci (1996) (0)
[Analysis of STS (sequence tagged site): microsatellite marker]. (1996) (0)
THE OVERLAPPING MECHANISM OF WEIGHT LOSS RESISTANCE AND REBOUND FROM A SIGNIFICANT WEIGHT LOSS IN OBESE SUBJECTS: P1.240 (2004) (0)
781-5 Dyslipidemia, Insulin Resistance and Blood Pressure Status in Non-obese, Japanese Populations: Comparisons Between Young and Elderly Subjects (1995) (0)
[Cosegregation studies in spontaneously hypertensive rats]. (1993) (0)
Co-Transfection of Human Hepatocyte Growth Factor and Prostacyclin Synthase Gene Enhanced Therapeutic Angiogenesis in Rat and Rabbit Ischemia Model (2003) (0)
[Ultrasonographic measurement of intima-media thickness in the diagnosis of arteriosclerosis]. (2004) (0)
[Enzyme immunoassay of hormones (author's transl)]. (1977) (0)
3 Functional Analysis of Novel Antimicrobial Peptide, AG (Angiogenic Peptide)-30, with Angiongenic Property, toward Clinical Application(The 71st Annual Scientific Meeting of the Japanese Circulation Society) (2007) (0)
[Geriatric medicine of the 21st century--perspectives for the practice, education]. (2001) (0)
Acceleration of neointimal hyperplasia in Lp(a) transgenic mice : Contribution of Lp(a) in the pathogenesis of vascular disease (2002) (0)
FRS-158 Association of Beta1-adrenergic Receptor Gene Polymorphism with Cardiovascular Function in Japanese Population : the Ohasama Study(Hypertension (H) : FRS19)(Featured Research Session (English)) (2004) (0)
Future Medicine in the Post-Genome Age — Targeting tailored medicine for hypertension — (2003) (0)
EFFECT OF CAPTOPRIL ON RENAL VASCULAR RESISTENCE, RENIN, PROSTAGLANDINS AND KININ IN THE ISOLATED PERFUSED KIDNEY : PROCEEDINGS OF THE 47th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY : Hypertension (1983) (0)
[A case of idiopathic retroperitoneal fibrosis associated with localized swelling and pain on bilateral lower legs]. (1985) (0)
[Combination effect of H2-receptor antagonist and mucosal protective agent on hemodynamics in the gastric mucosa]. (1986) (0)
[Aging and blood pressure]. (2000) (0)
Erratum: The combination of hypertension to prevent cardiovascular events (COPE) trial: Rationale and design (Hypertension Research (2005) vol. 28 (331-338)) (2006) (0)
[Concept and clinical character of hypertension in the elderly]. (2005) (0)
[Etiological studies of hypertension. G. APRL (antihypertensive polar renomedullary lipid)]. (1984) (0)
Title Page / Table of Contents, Supplement 1, 1992 (1992) (0)
Effects of angiotensin I converting enzyme inhibitors on the renal excretory function, hemodynamics and renin release in isolated perfused rat kidney. (1983) (0)
[Gene therapy for diabetic microangiopathy]. (2010) (0)
135 Is reduced insulin sensitivity related to the onset and the severity of essential hypertension (1993) (0)
A new orally active hypotensive peptide, N-(dibenzyloxyphosphinoyl)-L-alanyl-L-prolyl-L-proline (PAPP). (1984) (0)
[Idiopathic Addison disease, autoimmune adrenalitis]. (2000) (0)
Long Term Evaluation of Results from the First Stage in the Clinical Trial of Gene Therapy for Peripheral Arterial Disease (2003) (0)
Hypotensive activity of 1-O-hexadecyl-2-O-acetyl-sn-glycero-3-phosphocholine in rats with various types of hypertension. (1983) (0)
Gene Therapy for Myocardial Infarction: A Real Medicine in the Next Millenium? (2000) (0)
Development of a Novel Ribbon-type Decoy Oligonucleotides to Treat Renal Damages Induced by Hypertension and Diabetes(Kidney/Renal Circulation 1 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (0)
(2) Recent Advances in Clinical Application of Blockers of Renin-Angiotensin System (1982) (0)
Effects of Elevated Blood Pressure on Tissue Distribution of Hepatocyte Growth Factor (HGF) in the Rat (1996) (0)
Abstract P203: Combination of Diet and Exercise is Preferred for Weight Loss and Weight Loss-Induced Blood Pressure Reduction (2011) (0)
Prevention of Restenosis After Angioplasty: Efficacy of Antisense Strategy Against Cell Cycle Regulatory Genes: ―アンチセンス技術の応用と遺伝子導入― (1995) (0)
Plasma Adiponectin Concentration and Renal Function, and its Predictive Role in Cardiovascular Disease (Kidney/Renal Circulation 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (0)
Using Hepatocyte Growth Factor Gene to Treat Severe Peripheral Arterial Disease (0)
Abstract: P1377 ARG16GLY OF THE β2-ADRENOCEPTOR POLYMORPHISM PREDICTS THE ONSET OF DYSLIPIDEMIA THROUGH INSULIN RESISTANCE (IR) IN NORMOTENSIVE MEN (2009) (0)
[Gene therapy for peripheral arterial diseases in diabetes mellitus]. (2002) (0)
[Biochemistry of renin]. (1982) (0)
[Problematic issues for diagnosis of diabetes mellitus in the elderly]. (2002) (0)
[Factors regulating circulation and hypertension--a molecular biological approach]. (1997) (0)
[The long term effect of the oral converting enzyme inhibitor captopril in hypertensive patients (author's transl)]. (1980) (0)
[Molecular genetics of myotonic dystrophy--population genetics of the CTG repeat expansion of the MTPK gene]. (1997) (0)
[HGF as a key molecule in cardiovascular diseases]. (2001) (0)
Prevention myocardial injury and fibrosis by angiotensin ii blockade in cariomyopathic hamster; potential contribution of a novel anti-fibrotic facter, HGF (1998) (0)
[Novel therapeutics in cardiovascular disease]. (2001) (0)
REGIONAL PULSE WAVE VELOCITY AS PROGNOSTIC IMPACT IN HYPERTENSION: PP.2.56 (2010) (0)
[A case of suspected allergic granulomatous angiitis following surgery of Sipple's syndrome]. (1987) (0)
The antihypertensive efficacy of budralazine in essential hypertension and hypertension with complications (1988) (0)
A case of first trimester prenatal diagnosis of 21-hydroxylase deficiency with human complement C4 cDNA probe. (1990) (0)
OJ-195 Pivotal Roles of Deubiquitinating Enzymes UCHL1, HAUSP, and CYLD in Vasculature as an Anti-proliferative and Anti-inflammatory Effect(Atherosclerosis, basic-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society) (2007) (0)
Dinucleotide repeat polymorphism at the D8S1054 (1995) (0)
Serum hepatocyte growth factor concentration is a specific marker of endothelial dysfunction in humans (2002) (0)
A Patient With Medullary Thyroid Carcinoma Associated With Polyneuropathy (1980) (0)
P-148: Genetic involvement of T+31C polymorphism in angiotensinogen gene for daytime and nighttime blood pressure: The O study (2001) (0)
[Positional cloning of susceptibility genes for non-insulin-dependent diabetes mellitus]. (1998) (0)
IP-0051 Adiponectin I164T mutations is associated with the metabolic syndrome and coronary artery disease (2003) (0)
[Comparison of blood pressure responses to captopril, an orally active converting enzyme inhibitor, in rats with various forms of experimental hypertension (author's transl)]. (1980) (0)
MPS 03-08 ON-TREATMENT BLOOD PRESSURE AND CARDIOVASCULAR OUTCOMES IN OLDER ADULTS WITH ISOLATED SYSTOLIC HYPERTENSION: VALSARTAN IN ELDERLY ISOLATED SYSTOLIC HYPERTENSION (VALISH) STUDY (2016) (0)
Two dinucleotide repeat polymorphisms at the D8S1442 and D8S1443 loci (1995) (0)
, Activating Elements Regulate Blood Pressure in the Brain − Angiotensinogen Gene (1999) (0)
IMIDAPRIL PREVENTED ATHEROSCLEROTIC CHANGES DUE TO HYPERTENSION AND DIABETES IN RATS: P 229 (2004) (0)
VEGF (164) INDUCES TRANSFORMATION OF BLOOD CELLS PRECURSORS INTO ENDOTHEUAL CELLS IN DEVELOPING POSTERIOR BLOOD ISLAND: P 235 (2004) (0)
Intercellular Adhesion Molecule-1 G241R Polymorphism Influences Increasing Arterial Stiffness (2003) (0)
NF-κB as a Therapeutic Target for Transcription Factor Decoy Strategy in Inflammatory Diseases (2003) (0)
[Case report of a patient with pseudohypoparathyroidism associated with slight increase in serum level of unconjugated bilirubin]. (1990) (0)
Effects of Angiotensin-Converting Enzyme Inhibitors on Blood Pressure, the Renin-Angiotensin System and Heart Weight in Spontaneously Hypertensive Rat (1990) (0)
AL amyloidosis with severe orthostatic hypotension. (2004) (0)
INHIBITORY EFFECTS OF CERIVASTATIN ON NEOINTIMAL FORMATION AFTER BALLOON INJURY IN PORCINE CORONARY ARTERY: P 307 (2004) (0)
Abstract 4437: Genome-Wide Association Study for the Response to Antihypertensive Medication: HOMED-BP-GENE Study (2008) (0)
[Partial Addison's disease]. (1993) (0)
Title Page / Table of Contents, Supplement 1, 1996 (1996) (0)
Ng atopic dermatitis (2002) (0)
[Angiotensin type 1 receptor blocker reduced proteinuria in patients of focal glomerular sclerosis]. (2004) (0)
HEALING AND PREVENTING BY NF-kappaB CAUSED DISEASES (1996) (0)
Decoy Oligodeoxynucleotides as Viable Pharmaceutical Drugs (2004) (0)
1, 25-(OH)_2D_3 BINDS SPECIFICALLY TO RAT VASCULAR SMOOTH MUSCLE CELLS AND STIMULATES THEIR PROLIFERATION IN VITRO : Arteriosclerosis : 53 Annual Scientific Meeting, Japanese Circulation Society (1989) (0)
Functional Analysis of Cis-element and Bindibng Protein as Regulators of Angiotensinogen Generation in SHR (1998) (0)
PJ-152 Upregulation of endothelial plasminogen activator inhibitor-1 (PAI-1) expression by hyperglycemia through activation of apoptosis signal-regulating kinase 1 (ASK1)(Endothelium/NO 3 (H) : PJ26)(Poster Session (Japanese)) (2004) (0)
Vascular Specific Organogenesis from Embryonic Stem Cells on Three Dimensional Layer of Matrigel (2003) (0)
[Functional diagnosis of endocrine gland neoplasms]. (1976) (0)
P683 SYMPATHETIC HYPERACTIVITY AND HYPERINSULINEMIA ARE RELATED WITH OBESE-INDUCED BP ELEVATION IN YOUNG SUBJECTS (1997) (0)
Preliminary clinical results from TREAT-HGF : Gene therapy for PAD (2002) (0)
The soluble form of Fas ligand may stimulate angiogesisthrough up-regulation of eNOS under hypoxia (2002) (0)
Inhibition of endothelin by nicorandil : hemodynamic and electrocardiographic evaluation in dogs (1990) (0)
Modification of plasmid DNA-based gene transfer into central nerve system (2004) (0)
THE IMBALANCE OF SYMPATHETIC/PARASYMPATHETIC NERVOUS SYSTEM INFLUENCES ON MORNING BLOOD PRESSURE ELEVATION: OP 012 (2004) (0)
Deletion polymorphism of angiotensin-converting enzyme gene associates with decrease of coronary flow reserve (2001) (0)
Effects of an Antihypertensive Combination Based on the Long-Acting Calcium Channel Blocker Benidipineon Vascular and Renal Events: a Sub-Analysis of the COPE Trial (2015) (0)
O3-01 Genetic risk factors and modulators of hypertension in the Ohasama study (2004) (0)
alpha-Adrenergic blocking action of 1-O-hexadecyl-2-O-acetyl-sn-glycero-3-phosphocholine in rats. (1983) (0)
Two dinucleotide repeat polymorphisms at the D8S1444 and D8S1445 loci (1996) (0)
Modified low density lipoprotein stimulates nitric oxide synthesis in vascular smooth muscle cells. (1992) (0)
[The latest review of therapeutic angiogenesis using angiogenic growth factors to peripheral arterial diseases]. (2002) (0)
E13 – Hormonal mechanisms in blood pressure (BP) reduction during hemodialysis (HD) in patients with chronic renal failure(CRF) (1995) (0)
Type 2 diabetes and a history of coronary heart disease are additive cardiovascular risks in high-risk hypertensive patients: a subanalysis of the CASE-J Ex (2013) (0)
ESSENTIAL HYPERTENSION (1960) (0)
[Crucial role of apoptogenic protein in cellular apoptosis and senescense]. (2011) (0)
Angiogenesis induced by hepatocyte growth factor (HGF) : The possibility of gene therapy for ischemic heart diseases (1999) (0)
B001: Effects of weight reduction, ACE inhibitor and angiotensin II antagonist on obesity hypertension (2000) (0)
A Bglll polymorphism forpKNB46 [D19S73] (1990) (0)
[Development of new therapeutics based on the concept "death and regeneration"]. (2000) (0)
P1-445: Gene transfer of HGF by microbubble-enhanced ultrasound improves Aβ-induced memory impairment in mice (2006) (0)
Abstract 749: A New Candidate Gene of Essential Hypertension: CYP4A11 Gene, Regulating a 20-Hydroxyeicosatetraenoic Acid Production (2006) (0)
[Determination of inactive renin by cryoactivation and its clinical application (author's transl)]. (1980) (0)
IS052 ACTIVATED CELLS INDUCE UP-REGULATION OF FAS ANTIGEN IN CULTURED ENDOTHELIAL CELLS (1997) (0)
RIBOZYME OLIGONUCLEOTIDES AGAINST TGF-BETA TRANSFERRED BY ULTRASOUND INHIBITED THE PROGRESSION OF DISEASES IN ANTI-THY1 MODEL: P 113 (2004) (0)
[A megatrial of ARB in Japan--CASE-J]. (2002) (0)
S22-2 RECENT PROGRESS IN MOLECULAR BASIS OF ESSENTIAL HYPERTENSION (2007) (0)
[Pathogenesis and treatment of hypertension]. (1990) (0)
THE DIFFERENCES IN INSULIN SENSITIVITY BETWEEN BEFORE AND AFTER DRUG MEDICATION BY CALCIUM ANTAGONIST(NIFEDIPINE)IN ESSENTIAL HYPERTENSIVE PATIENTS (1993) (0)
82. Angiotensin converting enzyme inhibitor diminished reflex tachycardia by modulating neurotransmitter release in ventrolateral medulla (1991) (0)
Differential blood pressure responses to oral and central salt administration in two substrains of Dahl rats. (1990) (0)
THE PROTECTIVE EFFECT OF KLOTHO PROTEIN AGAINST OXIDATIVE STRESS: P 673 (2004) (0)
Hypertension and Risk Stratification (2008) (0)
Effects of manidipine hydrochloride on proliferation and glycosaminoglycan synthesis of cultured vascular smooth muscle cells. (1992) (0)
Effect of Electroacupuncture on Stress-induced High Blood Pressure via Autonomic Nervous System in Normotensive Young Adults (2021) (0)
Endocrine hypertension Comprehensive endocrinology series. Edited by E.G. Biglieri; associate editor: J.C. Melby. Published 1990 by Raven Press, New York. No. of pages: 298. ISBN: 0-88167-587-3. Price at Dec. 1990: $119.00 (1992) (0)
Results of Safety from Human Clinical Gene Therapy Using HGF (TREAT-HGF) (2003) (0)
[Therapy for hypertension: EBM and tailor-made medicine]. (2003) (0)
Moderated Poster Session II: Epidemiology and public health (2010) (0)
[Gene polymorphisms of angiotensin II-type 1 receptor in hypertension]. (2004) (0)
[Hypertension in elderly patients]. (2004) (0)
-490- CONTRIBUTION OF AREA POSTREMA AND ANTEROVENTRAL THIRD VENTRICLE TO PRESSOR ACTIONS OF ANGIOTENSIN II IN DOGS (1987) (0)
[Renin inhibitors]. (1985) (0)
[Senescence gene and anti-aging medicine]. (2008) (0)
Detection of MspI RFLP in human THY1 gene by the polymerase chain reaction (1995) (0)
Aphidicolin-resistant human cell lines resistant to uv and bleomycin (1993) (0)
[History and concepts of the renin-angiotensin system]. (2005) (0)
Effects of an angiotensin II antagonist; [sarcosine 1, isoleucine 8] angiotensin II, on blood pressure, plasma renin activity and plasma aldosterone concentration in hypertensive and normotensive subjects taking oral contraceptives. (1979) (0)
[Evaluation of the relationship between aging and the renin-angiotensin system using direct radioimmunoassay with monoclonal antibodies]. (1988) (0)
[Adrenoceptor dysfunction in essential hypertension]. (1992) (0)
Periostin as a Anti-adhesion Molecule Responsible for Ventricular Dilation(Heart Failure, Basic 3 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (0)
EFFICACY OF THERAPEUTIC ANGIOGENESIS BYTRANSFECTION OF HEPATOCYTE GROWTH FACTOR GENE USING LEFT VENTRICULAR ELECTROMECHANICAL MAPPING IN PORCINE MYOCARDIAL INFARCTION MODEL: P 303 (2004) (0)
Erratum to “A new Lp(a) assay that is unaffected by apo(a) size polymorphism” (2000) (0)
OJ-188 Idetification of a novel apoptosis gene in cultured atherosclerotic smooth muscle cells(Atherosclerosis, Basic 2 (IHD) : OJ22)(Oral Presentation (Japanese)) (2004) (0)
PJ-378 Forkhead transcriptional factor induces apoptosis in vascular smooth muscle cells, and reduces neointima formation after balloon injury in rats(Apoptosis/Necrosis/Regeneration 1 (M) : PJ63)(Poster Session (Japanese)) (2004) (0)
Preclinical detection in Japanese families with myotonic dystrophy using polymorphic DNA markers (1989) (0)
CHORONIC ADMINISTRATION OF ANGIOTENSIN II RECEPTOR ANTAGNOST,TCV-116 PREVENTED CONGESTIVE HEART FAILURE IN THE CARDIOMYOPATHIC HAMSTER(UM-X7.1) (1993) (0)
[The responses of active and inactive plasma renin to various conditions in normal subjects and the role of renal or plasma kallikrein in activation of inactive renin]. (1982) (0)
-0510-INTRAVENTRICULAR INFUSION OF HYPERTONIC NACL INCREASES BLOOD PRESSURE BY REDUCING NOREPINEPHRINE RELEASE OF THE VENTROLATERAL NEDULLA (1990) (0)
Studies on the genes specifically expressed in the atherosclerotic plaques of ApoE-deficient mice (2002) (0)
Essential hypertension ( DIME ) study diuretics : Diuretics In the Management of hypertensive patients receiving thiazide evaluation of risk for type 2 diabetes in A randomised controlled trial for the for the DIME Investigators (2014) (0)
[Application of decoy strategy]. (1996) (0)
The role of oxidative stress in apoptosis of endothelial cells (2000) (0)
CLINICAL CHARACTERISTICS OF ESSENTIAL HYPETENSION WITH HYPOADIPONECTINEIMA RELATED WITH INCREASED PLASMA ALDOSTERONE CONCENTRATION: P 190 (2004) (0)
Future Medicine in the Post-Genome Age (2003) (0)
[Ongoing clinical trials by vascular statin, cerivastatin]. (2001) (0)
OR-42: A positive family history of hypertension and sympathetic overactivity are predictors of subsequent weight gain and bp rise (2003) (0)
Potential of Transcription Factor Decoy Oligonucleotides as Therapeutic Approach (2004) (0)
Correction: hutchinson-gilford progeria syndrome in a 45-year-old man (1987) (0)
Inhibition of Restenosis by Beraprost Sodium (a Prostaglandin 12 Analogue) in the Porcine Coronary Artery after Angioplasty (2003) (0)
[Red-cell sodium content in various hypertensions (author's transl)]. (1981) (0)
GENETIC INFLUENCES OF BETA ADRENOCEPTOR SINGLE NUCLEOTIDE POLYMORPHISMS ON HYPERTENSIVE COMPLICATIONS: P3.187 (2004) (0)
Clinical efficacy and tolerability of candesartan cilexetil. Candesartan Study Groups in Japan. (1999) (0)
Angiotensin-I Converting Enzyme Inhibitor Improves Decreased Endothelial Function in Elderly Hypertensive Patients with Arteriosclerosis Obliterans (2000) (0)
Contribution of Cardiovascular Hypersensitivit Orthostatic Hypertension and the Extreme Dipper Phenomenon y to (2006) (0)
[Positional cloning of the genes for progeroid syndromes]. (1996) (0)
QOL evaluation in hypertension therapies. (1994) (0)
[Administration of angiotensin I converting enzyme inhibitor captopril, in a case of renal crisis of scleroderma--the effects of captopril to the temperature of the skin lesion in scleroderma (author's transl)]. (1981) (0)
Effects of pravastatin on serum levels of triglycerides and HDL cholesterol in patients with hypercholesterolemia (1994) (0)
Mineralocorticoid activity and effect on blood pressure of synthetic 16^|^beta;-OH-dehydroepiandrosterone and 16-oxo-androstenediol in rats (1977) (0)
[DNA diagnosis of myotonic dystrophy in a family]. (1993) (0)
(cid:1) 2 - and (cid:1) 3 -Adrenergic Receptor Polymorphisms Are Related to the Onset of Weight Gain and Blood Pressure Elevation Over 5 Years (2005) (0)
C036 Usefulness of wavelet-based real-time analysis of blood pressure and heart rate variability (1998) (0)
A single nuctreotide polymorphism in the HSD11B1 locus associates with blood pressure (2002) (0)
Obesity, hypertension and weight gain-induced blood pressure elevation. (1999) (0)
[Treatment of hypertension in the elderly]. (1988) (0)
Effect of Cromakalim (BRL 34915) on hemodynamic and electrocardiographic changes induced by endothelin in dogs (2005) (0)
Activation of Apoptosis Signal-Regulating Kinase 1 via a Protein Kinase C-Dependent Pathway Mediates Plasminogen Activator Inhibitor-1 Expression in Endothelial Cells (2003) (0)
NF-κB decoy prevents the progression of anti-GBM glomerulonephritis in rats (1999) (0)
[Clinical significance of analysis of glycated serum protein, glycated albumin and fructosamine in the diagnosis of diabetic diseases]. (1990) (0)
[Treatment of hypertension in the elderly patients with complications]. (1997) (0)
Role of geriatric medicine in a super-aged society (2018) (0)
Effect of aspirin on the pressor activity of endothelin. (1990) (0)
PJ-278 Important Role of Nuclear Factor-κ(NF κB) in Neointimal Formation in Porcine Balloon Injury Model(Infection/Inflammation/Immunity 3 (H) : PJ47)(Poster Session (Japanese)) (2004) (0)
[NEP inhibitor (neutral endopeptidase inhibitor)]. (2000) (0)
[Regulation of the circulation system]. (2000) (0)
Responses of active and inactive plasma renin to insulin-induced hypoglycemia in normal subjects. (1984) (0)
No increase in human HGF concentration in the patients transfected with human HGF plasmid : preliminary clinical results from TREAT-HGF (2002) (0)
P021: Changes in Body Mass Index (BMI) and BP levels in a Japanese male population in a longitudinal study of one year (1998) (0)
Effect of 1-hexadecyl-2-acetyl-sn-glycero-3-phosphorylcholine on blood pressure by intra-lateral ventricular injection in the rat. (1984) (0)
Structure of angiotensin II-binding site probed with diaminoalkanes. (1984) (0)
[Plasma motilin assay and the clinical significance]. (1990) (0)
Splenomegaly in Papua New Guineans and in Japanese living in Papua New Guinea: report of research and exchange program of Osaka University with the South Pacific region. (1989) (0)
Erratum: Effects of candesartan and amlodipine on cardiovascular events in hypertensive patients with chronic kidney disease: Subanalysis of the CASE-J study (Hypertension Research (2009) 32 (505-512) DOI: 10.1038/hr.2009.44) (2009) (0)
IS049 APOPTOSIS MEDIATED BY P53 THROUGH BAX PATHWAY IN HUMAN AORTIC VASCULAR SMOOTH MUSCLE CELLS (1997) (0)
Title Pancreatic β Cell-specific Expression of Thioredoxin , an Antioxidative and Antiapoptotic Protein , Prevents Autoimmune and Streptozotocin-induced Diabetes (0)
DIFFERENT METABOLISM IN URIC ACID BETWEEN NONOBESE AND OBESE SUBJECTS, AND BETWEEN NORMOTENSIVE AND HYPERTENSIVE SUBJECTS: OP 094 (2004) (0)
LONG-TERM EFFECTS OF CANDESARTAN AND AMLODIPINE ON CARDIOVASCULAR EVENTS IN HIGH-RISK HYPERTENSIVE PATIENTS: RESULTS OF CASE-J EXTENSION: HT.2.04 (2010) (0)
Recovery of Learning and Memory by Gene Therapy Using Hepatocyte Growth Factor Gene After Focal Cerebral Ishcemia in Rats(Gene Therapy/Genetic Engineering (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (0)
[Inhibition of angioten converting enzyme by phosphryl derivatives in rats (author's transl)]. (1981) (0)
[Towards cloning the gene responsible for myotonic dystrophy]. (1990) (0)
[Overview on diagnosis, treatment and therapeutic angiogenesis for arteriosclerosis obliterans]. (2006) (0)
[Synthesis of angiotensin-converting enzyme inhibitors and its application to experimental hypertensive rat for understanding the pathogenesis of renovascular hypertension (author's transl)]. (1978) (0)
[Current topics on hypertension. Possibility for gene therapy]. (1999) (0)
713. NFkB Decoy Oligodeoxynucleotides Inhibit Osteoclast Differentiation and Activation In Vitro and Improve Osteoporosis of Ovariectomized and Vitamin C Difficient Rat Models (2006) (0)
COLM Results: Hypertensive Patients Aged >=75 Years Have Better Clinical Outcomes and Fewer AEs on CCBs than Diuretics (2013) (0)
P008 Obesity and blood pressure levels in normotensive subjects in a longitudinal study (1998) (0)
Differences in Mechanisms Between Weight Reduction Sensitive and Insensitive Blood Pressure Reduction in Obese Subjects (2000) (0)
[Clinical application of angiotensin II analogue (1-sarcosine, 8-isoleucine-angiotensin II) (author's transl)]. (1974) (0)
Title Page / Table of Contents, Supplement 1, 1993 (1993) (0)
ASSOCIATION BETWEEN HGF GENE POLYMORPHISM AND SUSCEPTIBILITY TO ESSENTIAL HYPERTENSION IN JAPANESE POPULATION: P 638 (2004) (0)
Pharmacological activity of NF-κB decoy (II). Effect of NF-κB decoy on Colon26-induced cachexia in mice. (1996) (0)
[Pathophysiology and diagnosis of endocrine hypertension (author's transl)]. (1978) (0)
The Effect of Ticlopidine on the Release of Platelet-Derived Growth Factor from Platelets (1989) (0)
Treatment of the Geriatric Patients (1988) (0)
EFFECTS OF ANTIHYPERTENSIVE DRUGS IN THE PREVENTION OF NEW‐ONSET DIABETES MELLITUS IN PATIENTS WITH HYPERTENSION AT HIGH‐RISK OF CARDIOVASCULAR EVENTS IN RELATION TO AGING (2010) (0)
-0356-CALCIUM SIGNAL TRANSDUCTION EVOKED BY LOW DENSITY LIPOPROTEIN IN VASCULAR SMOOTH MUSCLE CELLS (1990) (0)
Advances in the Treatment of Hypertension in the Elderly : Japanese Guidelines for Treatment of Hypertension in the Elderly (2003) (0)
Genetic Predisposition to Hypertension and Cardiovascular Disease (2003) (0)
Anti-Apoptotic Effect of Human Telomerase Reverse Transcriptase on Endothelial Cells under Oxidative Stress, Independent of Telomere Elongation and Telomerase Activity (2013) (0)
IMPACT OF SERUM URIC ACID ON RENAL FUNCTION AND CARDIOVASCULAR EVENTS IN HYPERTENSIVE PATIENTS WITH CHRONIC KIDNEY DISEASE: PP.8.203 (2011) (0)
[Angiotensin II type 1 receptor gene]. (2006) (0)
[A study on the pathophysiology and diagnosis of adrenocortical insufficiency using angiotensin II blocker (author's transl)]. (1978) (0)
THE FREQUENCY OF ORTHOSTATIC HYPOTENSION IN ELDERLY PATIENTS WITH ESTARLISHED HYPERTENSION(EHT),iSOLATED SYSTOLIC HYPERTENSION(SHT) AND BORDERLINE HYPERTENSION(BHT) (1993) (0)
[Gene therapy for peripheral arterial disease]. (2005) (0)
OE-206 Development of Ribbon Type NF-κ B Decoy Oligodeoxynucleotides(Genetics/Genetically engineered models/Gene therapy-1(H/M), The 71st Annual Scientific Meeting of the Japanese Circulation Society) (2007) (0)
[Gene and elderly hypertension]. (2001) (0)
[Progressive autonomic failure]. (1996) (0)
P230 EFFECTS OF AGE ON PREVALENCE OF HYPERINSULINEMIA IN NON-OBESE JAPANESE MEN (1997) (0)
Gene Through Induction of Apoptosis Inhibition of Growth of Human Vascular Smooth Muscle Cells by Overexpression of p21 (2013) (0)
[Proceedings: Detection of renin-angiotensin-aldosterone system in idiopathic edema]. (1974) (0)
Response to Odawara et al. (1996) (0)
Abstracts from the 43rd Kansai Calcium Conference (2000) (0)
Development of a novel gene transfer method mediated by ultrasound with microbubbles (2002) (0)
A case of suspected allergic granulomatous angiitis following the operation of sipple's syndrome. (1987) (0)
[Enzyme-labelled immunoassay for plasma cortisol and its clinical application (author's transl)]. (1977) (0)
Apolipoprotein E gene polymorphism and diabetic microangiopathy in non-insulin-dependent diabetes mellitus (1995) (0)
[Type 1 diabetes susceptibility genes on human chromosome 2q]. (1997) (0)
I29 – Dyslipidemia, insulin resistance and blood pressure status in non-obese, Japanese populations: Comparisons between young and elderly subjects (1995) (0)
[Clinical study on the hypotensive effect of captopril in hypertensive patients-its mechanism (author's transl)]. (1980) (0)
-1040- COMPARISONS OF DYSLIPIDEMIA AND INSULIN RESISTANCE BETWEEN THE YOUNG SUBJECTS WITH AND WITHOUT FAMILY HISTORY OF HYPERTENSION(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY) (1995) (0)
Differences in Insdin and Sympathetic Responses to Glucose Ingestion Due to Family History of Hypertension (2003) (0)
836 Is normalization of blood pressure safe and beneficial in elderly hypertensive patients?: SuBAnalysis of the VALISH study (2012) (0)
[An 88-year-old female case of hyperalphalipoproteinemia associated with deficiency of cholesteryl-ester transfer activity]. (1992) (0)
Title Page / Table of Contents, Supplement 1, 1997 (1997) (0)
Present and Future in the gene therapy for cardiovascnlar disease (1999) (0)
P4-067 Development of in vitro Abeta sink assay, to identify the dissociation of soluble Abeta from fibrils (2006) (0)
[Hutchinson-Gilford progeria syndrome]. (2000) (0)
Olmesartan Medoxomil (2012) (0)
PJ-032 Fas Ligand Expression Levels in Mononuclear Cells May Indicate the Degree of Improvement of Endothelial Function by Statin(Endothelium-5 (H) PJ6,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society) (2006) (0)
-0351-THE EFFECT OF INIERLEUKIN-6 ON PROLIFERATION OF CULTURED VASCULAR SMOOTH MUSCLE CELLS (1990) (0)
Central Depressor Mechanism of Angiotensin II Type 1 Receptor Antagonist in the Spontaneously Hypertensive Rat (1995) (0)
[Endocrine aspect of endothelin]. (1991) (0)
-441- HEMODYNAMIC, RENAL AND HORMONAL EFFECTS OF α-HUMAN ATRIAL NATRIURETIC PEPTIDE INJECTION IN PATIENTS WITH CONGESTIVE HEART FAILURE (1987) (0)
[Genetics of essential hypertension]. (2000) (0)
L11: Trend analysis of the prevalence of hyperinsulinemia during 10 years in young, non-obese, japanese men (1997) (0)
Abstract 3559: {beta}2-adrenoceptor Protein Expression Is Different Between Buffy Coat And Adipose Tissue (2007) (0)
Gene and environment interaction in the susceptibility to essential hypertension (2002) (0)
[A simple and direct radioimmunoassay for serum and urinary metanephrine]. (1983) (0)
[A case of late-onset Pick's disease with polyuria]. (1992) (0)
Favorable effects of statins beyond lipid lowering (2006) (0)
Treatment and prevention of diseases caused by NF-kappa B (1996) (0)
Plasma level of 8-hydroxydeoxyguanosine, a marker of oxidative stress, was correlated to endothelial dysfunction in hypertensive patients (2002) (0)
β3-Adrenergic Receptor Trp64arg Polymorphism Is Related with Endothelial Dysfunction via Increased Oxidized Stress in Proportion to Increasing Sympathetic Nervous Activity (2003) (0)
Inhibitory Effect of Chimera Decoy Oligodeoxynucleotides (ODN) against Ets and NFκ B on the Progression of Rabbit Experimental Aortic Aneurysms (AAA) (2003) (0)
Effects of the kallikrein-kinin system on phasic coronary vasospasm in dogs. (1989) (0)
[Prediction of type 1 diabetes by genetic analysis]. (1997) (0)
The Long Term Effect of the Oral Converting Enzyme Inhibitor, Captopril in Hypertensive Patients (1980) (0)
Effect of Native Lp ( a ) or Oxidized Lp ( a ) on VSMC Growth (2002) (0)
[Genetic aspects of hypertension--etiology of essential hypertension]. (1995) (0)
[Hypertension in the elderly-upto-date]. (1999) (0)
GNAS1/T393C POLYMORPHISM IS A GENETIC MODULATOR OF CARDIOVASCULAR RISK: THE OHASAMA STUDY (2004) (0)
D008: Association of genetic variants of angiotensin-I-converting enzyme and pneumonia in elderly subjects (2000) (0)
Preliminary clinical results from TREAT-HGF (Japan Trial to Treat Peripheral Arterial Disease by Therapeutic Angiogenesis Using HGF Gene Transfer) (2002) (0)
I28DOES DYSLIPIDEMIA AND INSULIN (INS) RESISTANCE RELATE TO BLOOD PRESSURE (BP), AGING AND BMI? (1995) (0)
Oncogenic hypophosphatemia: report of a case (1996) (0)
The suppressive effect of human parathyroid hormone related protein 1034 on endothelin 1 production in cultured endothelial cells (1992) (0)
[Presence of circulating suppressive factor for muscarinic acetylcholine receptor in senile dementia]. (1991) (0)
Improvement of Myocardial Dysfunction by Therapeutic Angiogenesis Induced by Transfection of HGF Gene in Porcine Chronic Myocardial Ischemia Model(Gene Therapy 2 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (0)
Lower Plasma Adiponectin Concentration Increases Risk for Hypertension (2003) (0)
P-618: Renin angiotensin system inhibition prevents naturally advanced left ventricular hypertrophy via oxidized stress suppression (2005) (0)
[Recent findings on ACTH]. (1981) (0)
[Cerebral infarction and asymptomatic arteriosclerosis obliterans in the elderly]. (1997) (0)
Changes in plasma active renin and prorenin after endoscopic retrograde pancreatography. (1989) (0)
P-325: Hepatocyte growth factor (HGF) is an index of arteriosclerosis in hypertensive patients. Correlation to pulse wave velocity (PWV) and serum HGF concentration (2001) (0)
[Treatment of hypertension in the elderly]. (1994) (0)
Prefer Angiotensin II receptor blockers (2002) (0)
Gene diagnosis of hypertension (2000) (0)
PE-347 Fas may have apoptosis-unrelated biological functions in the vasculature.(Molecular Biology, Vascular 3 (H) : PE59)(Poster Session (English)) (2004) (0)
[Treatment of hypertension in the elderly]. (1995) (0)
[Molecular biological approach to hypertension]. (1996) (0)
HYPOTENSIVE ACTIVITY OF SYNTHETIC RENOMEDULLARY ANTIHYPERTENSIVE LIPID, 1-0-HEXADECYL-2-0-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE : Hypertension (I) : 46th Annual Scientific Meeting, Japanese Circulation Society (1982) (0)
The Role of Hepatocyte Growth Factor (HGF) in Vasculogenesis and Angiogenesis in Xenopus Development (2003) (0)
191. Improvement of Myocardial Dysfunction by Therapeutic Angiogenesis Induced by Transfection of HGF Gene Using Left Ventricular Electromechanical Mapping in Porcine Chronic Myocardial Infarction Model (2004) (0)
1161-180 Which is the best pharmacological treatment for obese hypertensive patients with hyperuricemia? (2004) (0)
Potential of Microvascular Reperfusion with Adjunctive Pharmacological Intervention (2012) (0)
3P-0890 Clinical results from TREAT-HGF (Japan trial to treat peripheral arterial disease by therapeutic angiogenesis using hepatocyte growth factor gene transfer) (2003) (0)
[Treatment of hypertension in the elderly]. (1988) (0)
[Clinical characteristics and therapeutic strategy for acute myocardial infarction in the elderly]. (1996) (0)
[Clinical application of an angiotensin II analogue (ii). Blood pressure changes following the infusion of 1-sarcosine. 8-isoleucine angiotensin II in various hypertensive disorders and body fluid abnormalities (author's transl)]. (1976) (0)
-P118-ENDOTHELIN ENHANCES ADRENERGIC VASOCONSTRICTION IN RAT : Hypertension : FREE COMMUNICATIONS(III) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY (1989) (0)
A Simplified Direct Radioimmunoassay for Urinary Aldosterone (1979) (0)
Single Nucleotide Polymorphisms of Ligand-Receptor System of Monocyte Chemoattractant Protein-1 Influence Different Arterial Dysfunctions with Serum Interleukin-15 Elevation (2003) (0)
[Advances in molecular genetics of myotonic dystrophy]. (1993) (0)
IDENTIFICATION OF "NEUTRALIZING" GENE-GENE INTERACTION IN THE REGULATION OF BLOOD PRESSURE IN THE SHR-RELATED STRAINS (2013) (0)
Experimental Physiology - Themed Issue Cardiovascular Genomics Paper Does gene therapy become pharmacotherapy? (2005) (0)

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