Toshitsugu Sugimoto
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Computer Science
Toshitsugu Sugimoto's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science University of Tokyo
- Bachelors Computer Science University of Tokyo
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(Suggest an Edit or Addition)Toshitsugu Sugimoto's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia. (2003) (528)
- Serum osteocalcin level is associated with glucose metabolism and atherosclerosis parameters in type 2 diabetes mellitus. (2009) (414)
- Diagnostic criteria for primary osteoporosis: year 2012 revision (2013) (363)
- Plasma lipids and osteoporosis in postmenopausal women. (2002) (303)
- Japanese 2011 guidelines for prevention and treatment of osteoporosis—executive summary (2012) (288)
- Diabetic Patients Have an Increased Risk of Vertebral Fractures Independent of BMD or Diabetic Complications (2009) (279)
- Serum pentosidine levels are positively associated with the presence of vertebral fractures in postmenopausal women with type 2 diabetes. (2008) (238)
- Bisphosphonate-related osteonecrosis of the jaw: position paper from the Allied Task Force Committee of Japanese Society for Bone and Mineral Research, Japan Osteoporosis Society, Japanese Society of Periodontology, Japanese Society for Oral and Maxillofacial Radiology, and Japanese Society of Oral (2010) (231)
- Randomized Teriparatide [human parathyroid hormone (PTH) 1-34] Once-Weekly Efficacy Research (TOWER) trial for examining the reduction in new vertebral fractures in subjects with primary osteoporosis and high fracture risk. (2012) (212)
- Antiresorptive agent-related osteonecrosis of the jaw: Position Paper 2017 of the Japanese Allied Committee on Osteonecrosis of the Jaw (2016) (200)
- Metformin enhances the differentiation and mineralization of osteoblastic MC3T3-E1 cells via AMP kinase activation as well as eNOS and BMP-2 expression. (2008) (191)
- Clinical usefulness of measurement of fibroblast growth factor 23 (FGF23) in hypophosphatemic patients: proposal of diagnostic criteria using FGF23 measurement. (2008) (180)
- Adiponectin and AMP kinase activator stimulate proliferation, differentiation, and mineralization of osteoblastic MC3T3-E1 cells (2007) (175)
- Serum undercarboxylated osteocalcin was inversely associated with plasma glucose level and fat mass in type 2 diabetes mellitus (2010) (170)
- High extracellular calcium inhibits osteoclast-like cell formation by directly acting on the calcium-sensing receptor existing in osteoclast precursor cells. (1999) (159)
- Association of decreased calcium-sensing receptor expression with proliferation of parathyroid cells in secondary hyperparathyroidism. (2000) (144)
- Menin Is Required for Bone Morphogenetic Protein 2- and Transforming Growth Factor β-regulated Osteoblastic Differentiation through Interaction with Smads and Runx2* (2004) (140)
- Effects of high glucose and advanced glycation end products on the expressions of sclerostin and RANKL as well as apoptosis in osteocyte-like MLO-Y4-A2 cells. (2015) (136)
- Effects of teriparatide on bone mineral density and bone turnover markers in Japanese subjects with osteoporosis at high risk of fracture in a 24-month clinical study: 12-month, randomized, placebo-controlled, double-blind and 12-month open-label phases. (2010) (133)
- Hypophosphatemia induced by intravenous administration of saccharated ferric oxide: another form of FGF23-related hypophosphatemia. (2009) (132)
- Effects of an excess and a deficiency of endogenous parathyroid hormone on volumetric bone mineral density and bone geometry determined by peripheral quantitative computed tomography in female subjects. (2003) (132)
- Associations between components of the metabolic syndrome versus bone mineral density and vertebral fractures in patients with type 2 diabetes. (2009) (132)
- Serum osteocalcin level is positively associated with insulin sensitivity and secretion in patients with type 2 diabetes. (2011) (129)
- A new active vitamin D, ED-71, increases bone mass in osteoporotic patients under vitamin D supplementation: a randomized, double-blind, placebo-controlled clinical trial. (2005) (126)
- The combination of high glucose and advanced glycation end-products (AGEs) inhibits the mineralization of osteoblastic MC3T3-E1 cells through glucose-induced increase in the receptor for AGEs. (2007) (126)
- Clinical Trials Express: Fracture Risk Reduction With Denosumab in Japanese Postmenopausal Women and Men With Osteoporosis: Denosumab Fracture Intervention Randomized Placebo Controlled Trial (DIRECT) (2014) (126)
- Parathyroid hormone increases beta-catenin levels through Smad3 in mouse osteoblastic cells. (2006) (118)
- Advanced Glycation End Products, Diabetes, and Bone Strength (2016) (114)
- Involvement of calcium-sensing receptor in osteoblastic differentiation of mouse MC3T3-E1 cells. (2005) (113)
- Effects of high concentrations of glucose on PTH secretion in parathyroid cells. (1990) (113)
- Activations of ERK1/2 and JNK by Transforming Growth Factor β Negatively Regulate Smad3-induced Alkaline Phosphatase Activity and Mineralization in Mouse Osteoblastic Cells* (2002) (107)
- Stimulatory effect of growth hormone on bone resorption and osteoclast differentiation. (1996) (106)
- Relationships between serum adiponectin levels versus bone mineral density, bone metabolic markers, and vertebral fractures in type 2 diabetes mellitus. (2008) (105)
- Elevated sclerostin levels are associated with vertebral fractures in patients with type 2 diabetes mellitus. (2013) (105)
- Decreased PTH levels accompanied by low bone formation are associated with vertebral fractures in postmenopausal women with type 2 diabetes. (2012) (102)
- Regulation of plasma fibroblast growth factor 23 by calcium in primary hyperparathyroidism. (2006) (97)
- Smad3 Promotes Alkaline Phosphatase Activity and Mineralization of Osteoblastic MC3T3‐E1 Cells (2002) (96)
- Nationwide survey of fibroblast growth factor 23 (FGF23)-related hypophosphatemic diseases in Japan: prevalence, biochemical data and treatment. (2015) (96)
- Low Serum Level of the Endogenous Secretory Receptor for Advanced Glycation End Products (esRAGE) Is a Risk Factor for Prevalent Vertebral Fractures Independent of Bone Mineral Density in Patients With Type 2 Diabetes (2009) (93)
- Inactivation of Menin, the Product of the Multiple Endocrine Neoplasia Type 1 Gene, Inhibits the Commitment of Multipotential Mesenchymal Stem Cells into the Osteoblast Lineage* (2003) (91)
- Adiponectin is associated with changes in bone markers during glycemic control in type 2 diabetes mellitus. (2009) (89)
- Advanced Glycation End Products (AGEs), but not High Glucose, Inhibit the Osteoblastic Differentiation of Mouse Stromal ST2 Cells Through the Suppression of Osterix Expression, and Inhibit Cell Growth and Increasing Cell Apoptosis (2012) (89)
- Effect of high phosphate concentration on osteoclast differentiation as well as bone‐resorbing activity (2003) (88)
- Relationship between treatments with insulin and oral hypoglycemic agents versus the presence of vertebral fractures in type 2 diabetes mellitus (2010) (87)
- Effect of elevated extracellular calcium on the proliferation of osteoblastic MC3T3-E1 cells:its direct and indirect effects via monocytes. (1991) (84)
- Decrease in vitamin D receptor and calcium-sensing receptor in highly proliferative parathyroid adenomas. (2003) (83)
- Activation of AMP kinase and inhibition of Rho kinase induce the mineralization of osteoblastic MC3T3-E1 cells through endothelial NOS and BMP-2 expression. (2009) (76)
- Role of Osteoglycin in the Linkage between Muscle and Bone* (2012) (76)
- Prediction of bone mass change after parathyroidectomy in patients with primary hyperparathyroidism. (2000) (74)
- BMP/Wnt antagonists are upregulated by dexamethasone in osteoblasts and reversed by alendronate and PTH: potential therapeutic targets for glucocorticoid-induced osteoporosis. (2009) (74)
- Association of cognitive dysfunction with hippocampal atrophy in elderly Japanese people with type 2 diabetes. (2011) (73)
- Successful treatment of hyperphosphatemic tumoral calcinosis with long-term acetazolamide. (1995) (70)
- Thyroid hormone stimulates osteoclast differentiation by a mechanism independent of RANKL–RANK interaction (2004) (70)
- Serum Levels of Insulin-Like Growth Factor (IGF); IGF-Binding Proteins-3, -4, and -5; and Their Relationships to Bone Mineral Density and the Risk of Vertebral Fractures in Postmenopausal Women (2006) (69)
- Involvement of osteoprotegerin/osteoclastogenesis inhibitory factor in the stimulation of osteoclast formation by parathyroid hormone in mouse bone cells. (2000) (68)
- Carboxyl-terminal parathyroid hormone fragments stimulate osteoclast-like cell formation and osteoclastic activity. (1994) (67)
- Statins modulate the levels of osteoprotegerin/receptor activator of NFkappaB ligand mRNA in mouse bone-cell cultures. (2005) (67)
- Bone metabolism and fracture risk in type 2 diabetes mellitus. (2012) (67)
- Serum insulin-like growth factor-I is a marker for assessing the severity of vertebral fractures in postmenopausal women with type 2 diabetes mellitus (2011) (67)
- Relationships between undercarboxylated osteocalcin and vitamin K intakes, bone turnover, and bone mineral density in healthy women. (2010) (66)
- Active vitamin D possesses beneficial effects on the interaction between muscle and bone. (2014) (65)
- Parathyroid Hormone-Smad3 Axis Exerts Anti-apoptotic Action and Augments Anabolic Action of Transforming Growth Factor β in Osteoblasts* (2003) (64)
- Determinants of Bone Mineral Density and Spinal Fracture Risk in Postmenopausal Japanese Women (2001) (64)
- Testosterone increases osteoprotegerin mRNA expression in mouse osteoblast cells. (2004) (63)
- Defective O-glycosylation due to a novel homozygous S129P mutation is associated with lack of fibroblast growth factor 23 secretion and tumoral calcinosis. (2009) (63)
- The Calcium-sensing Receptor (CaR) is involved in strontium ranelate-induced osteoblast differentiation and mineralization. (2010) (63)
- Bone metabolism and fracture risk in type 2 diabetes mellitus [Review]. (2011) (63)
- Serum insulin-like growth factor-I level is associated with the presence of vertebral fractures in postmenopausal women with type 2 diabetes mellitus (2007) (62)
- Vitamin D insufficiency defined by serum 25-hydroxyvitamin D and parathyroid hormone before and after oral vitamin D3 load in Japanese subjects (2011) (61)
- Effect of natural menopause on serum levels of IGF-I and IGF-binding proteins: relationship with bone mineral density and lipid metabolism in perimenopausal women. (1997) (61)
- Menin Suppresses Osteoblast Differentiation by Antagonizing the AP-1 Factor, JunD* (2005) (61)
- Menin Inactivation Leads to Loss of Transforming Growth Factor β Inhibition of Parathyroid Cell Proliferation and Parathyroid Hormone Secretion (2004) (61)
- Combination of Obesity with Hyperglycemia is a Risk Factor for the Presence of Vertebral Fractures in Type 2 Diabetic Men (2008) (61)
- Testosterone inhibits osteoclast formation stimulated by parathyroid hormone through androgen receptor (2001) (61)
- Parathyroid Hormone-responsive Smad3-related Factor, Tmem119, Promotes Osteoblast Differentiation and Interacts with the Bone Morphogenetic Protein-Runx2 Pathway* (2011) (61)
- Marked and sustained increase in bone mineral density after parathyroidectomy in patients with primary hyperparathyroidism; a six‐year longitudinal study with or without parathyroidectomy in a Japanese population (2004) (60)
- The action of GH/IGF-I/IGFBP in osteoblasts and osteoclasts. (1997) (60)
- Serum Osteocalcin/Bone-Specific Alkaline Phosphatase Ratio Is a Predictor for the Presence of Vertebral Fractures in Men with Type 2 Diabetes (2009) (59)
- Risk Factors for Hip Fracture in Hemodialysis Patients (2002) (59)
- Multiple vertebral fractures are associated with refractory reflux esophagitis in postmenopausal women (2004) (58)
- Advanced glycation end product 3 (AGE3) suppresses the mineralization of mouse stromal ST2 cells and human mesenchymal stem cells by increasing TGF-β expression and secretion. (2014) (57)
- Serum calcium is positively correlated with fasting plasma glucose and insulin resistance, independent of parathyroid hormone, in male patients with type 2 diabetes mellitus. (2011) (56)
- The Presence and Severity of Vertebral Fractures is Associated with the Presence of Esophageal Hiatal Hernia in Postmenopausal Women (2002) (56)
- Mild renal dysfunction is a risk factor for a decrease in bone mineral density and vertebral fractures in Japanese postmenopausal women. (2010) (54)
- Statin suppresses apoptosis in osteoblastic cells: role of transforming growth factor-beta-Smad3 pathway. (2008) (54)
- Bone Mineral Density Is not Sensitive Enough to Assess the Risk of Vertebral Fractures in Type 2 Diabetic Women (2007) (52)
- Effect of Oral Alfacalcidol on Clinical Outcomes in Patients Without Secondary Hyperparathyroidism Receiving Maintenance Hemodialysis: The J-DAVID Randomized Clinical Trial (2018) (52)
- IGF-I mediates the stimulatory effect of high calcium concentration on osteoblastic cell proliferation. (1994) (52)
- Undercarboxylated osteocalcin is positively associated with free testosterone in male patients with type 2 diabetes mellitus (2013) (52)
- The threshold of bone mineral density for vertebral fracture in female patients with glucocorticoid-induced osteoporosis. (2006) (51)
- Effects of age, grip strength and smoking on forearm volumetric bone mineral density and bone geometry by peripheral quantitative computed tomography: comparisons between female and male. (2005) (51)
- Lifestyle-Related Metabolic Disorders, Osteoporosis, and Fracture Risk in Asia: A Systematic Review. (2016) (50)
- Effect of 1,25-dihydroxyvitamin D3 on cytosolic calcium in dispersed parathyroid cells. (1988) (50)
- Advanced glycation end products-induced reactive oxygen species generation is partly through NF-kappa B activation in human aortic endothelial cells. (2013) (50)
- Estrogen modulates osteoblast proliferation and function regulated by parathyroid hormone in osteoblastic SaOS-2 cells: role of insulin-like growth factor (IGF)-I and IGF-binding protein-5. (2000) (50)
- Causes and differential diagnosis of hypocalcemia--recommendation proposed by expert panel supported by ministry of health, labour and welfare, Japan. (2008) (49)
- Pathogenesis and diagnostic criteria for rickets and osteomalacia—proposal by an expert panel supported by the Ministry of Health, Labour and Welfare, Japan, the Japanese Society for Bone and Mineral Research, and the Japan Endocrine Society (2015) (48)
- Three-year denosumab treatment in postmenopausal Japanese women and men with osteoporosis: results from a 1-year open-label extension of the Denosumab Fracture Intervention Randomized Placebo Controlled Trial (DIRECT) (2015) (47)
- Profile of changes in bone turnover markers during once-weekly teriparatide administration for 24 weeks in postmenopausal women with osteoporosis (2013) (46)
- Association of Polymorphic Alleles of the Calcium-Sensing Receptor Gene with Parathyroid Hormone Secretion in Hemodialysis Patients (2000) (45)
- Dose–response study of denosumab on bone mineral density and bone turnover markers in Japanese postmenopausal women with osteoporosis (2012) (45)
- Association of polymorphic alleles of the calcium‐sensing receptor gene with the clinical severity of primary hyperparathyroidism (2001) (44)
- Association of Bone Mineral Density, Bone Turnover Markers, and Vertebral Fractures with All-Cause Mortality in Type 2 Diabetes Mellitus (2017) (44)
- Involvement of the Osteoinductive Factors, Tmem119 and BMP-2, and the ER Stress Response PERK–eIF2α–ATF4 Pathway in the Commitment of Myoblastic into Osteoblastic Cells (2014) (44)
- Relationship between bone biochemical markers versus glucose/lipid metabolism and atherosclerosis; a longitudinal study in type 2 diabetes mellitus. (2011) (44)
- The direct involvement of cAMP-dependent protein kinase in the regulation of collagen synthesis by parathyroid hormone (PTH) and PTH-related peptide in osteoblast-like osteosarcoma cells (UMR-106). (1992) (43)
- Time-dependent effects of vitamin K2 (menatetrenone) on bone metabolism in postmenopausal women. (2002) (43)
- Increased low-density lipoprotein cholesterol level is associated with non-vertebral fractures in postmenopausal women (2015) (43)
- Potential hippocampal region atrophy in diabetes mellitus type 2: a voxel-based morphometry VSRAD study (2010) (42)
- The extracellular calcium Ca2+o-sensing receptor is expressed in myeloma cells and modulates cell proliferation. (2002) (42)
- IGF‐I mediates the stimulatory effect of high phosphate concentration on osteoblastic cell proliferation (2002) (41)
- Advanced Glycation End Products-induced Vascular Calcification is Mediated by Oxidative Stress: Functional Roles of NAD(P)H-oxidase (2012) (41)
- Estrogen blocks parathyroid hormone (PTH)-stimulated osteoclast-like cell formation by selectively affecting PTH-responsive cyclic adenosine monophosphate pathway. (1996) (40)
- Advanced Glycation End-Products Induce Apoptosis of Vascular Smooth Muscle Cells: A Mechanism for Vascular Calcification (2016) (40)
- Pathogenesis and diagnostic criteria for rickets and osteomalacia - proposal by an expert panel supported by Ministry of Health, Labour and Welfare, Japan, The Japanese Society for Bone and Mineral Research and The Japan Endocrine Society. (2015) (39)
- Reduction in Endogenous Insulin Secretion is a Risk Factor of Sarcopenia in Men with Type 2 Diabetes Mellitus (2015) (38)
- Effects of a single injection of teriparatide on bone turnover markers in postmenopausal women (2012) (37)
- Effects of metformin and pioglitazone on serum pentosidine levels in type 2 diabetes mellitus. (2011) (37)
- Serum osteocalcin levels are inversely associated with abdominal aortic calcification in men with type 2 diabetes mellitus (2013) (37)
- Effects of bazedoxifene on bone mineral density, bone turnover, and safety in postmenopausal japanese women with osteoporosis (2011) (37)
- FAM5C is a soluble osteoblast differentiation factor linking muscle to bone. (2012) (36)
- Smad7 inhibits differentiation and mineralization of mouse osteoblastic cells. (2012) (36)
- Advanced glycation end products suppress osteoblastic differentiation of stromal cells by activating endoplasmic reticulum stress. (2013) (36)
- The activation of cAMP-dependent protein kinase is directly linked to the inhibition of osteoblast proliferation (UMR-106) by parathyroid hormone-related protein. (1991) (36)
- Efficacy of weekly teriparatide does not vary by baseline fracture probability calculated using FRAX (2015) (36)
- Carboxyl-terminal peptides from parathyroid hormone-related protein stimulate osteoclast-like cell formation. (1995) (35)
- Interaction of Tmem119 and the bone morphogenetic protein pathway in the commitment of myoblastic into osteoblastic cells. (2012) (34)
- Diabetes Mellitus-induced Bone Fragility (2018) (34)
- Serum DHEA-S level is associated with the presence of atherosclerosis in postmenopausal women with type 2 diabetes mellitus. (2008) (34)
- Smad3 differently affects osteoblast differentiation depending upon its differentiation stage. (2006) (34)
- Dexamethasone suppresses Smad3 pathway in osteoblastic cells. (2005) (33)
- Lack of cooperation between physicians and dentists during osteoporosis treatment may increase fractures and osteonecrosis of the jaw (2016) (33)
- Activation of AMP-activated protein kinase protects against homocysteine-induced apoptosis of osteocytic MLO-Y4 cells by regulating the expressions of NADPH oxidase 1 (Nox1) and Nox2. (2015) (33)
- The effects of once-weekly teriparatide on hip structure and biomechanical properties assessed by CT (2013) (32)
- Risedronate therapy in patients with mild-to-moderate chronic kidney disease with osteoporosis: post-hoc analysis of data from the risedronate phase III clinical trials (2017) (32)
- The uraemic toxin phenylacetic acid inhibits osteoblastic proliferation and differentiation: an implication for the pathogenesis of low turnover bone in chronic renal failure. (2007) (31)
- Bone fragility in male glucocorticoid-induced osteoporosis is not defined by bone mineral density (2009) (31)
- Protein kinase C is involved in PTH-induced homologous desensitization by directly affecting PTH receptor in the osteoblastic osteosarcoma cells. (1991) (31)
- Role of Parathyroid Hormone in Bone Fragility of Postmenopausal Women with Vitamin D Insufficiency (2011) (31)
- Quantitative ultrasound and vertebral fractures in patients with type 2 diabetes (2011) (31)
- Age-dependent changes in body composition in postmenopausal Japanese women: relationship to growth hormone secretion as well as serum levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3. (1998) (30)
- Constitutive expression of c-fos gene inhibits type 1 collagen synthesis in transfected osteoblasts. (1992) (30)
- Carboxyl-terminal parathyroid hormone fragments stimulate type-1 procollagen and insulin-like growth factor-binding protein-5 mRNA expression in osteoblastic UMR-106 cells. (1998) (30)
- The activation of cAMP-dependent protein kinase is directly linked to the regulation of osteoblast proliferation (UMR-106) by parathyroid hormone. (1991) (30)
- Baseline atherosclerosis parameter could assess the risk of bone loss during pioglitazone treatment in type 2 diabetes mellitus (2010) (30)
- The activation of cAMP-dependent protein kinase is directly linked to the stimulation of bone resorption by parathyroid hormone. (1992) (30)
- Effect of parathyroidectomy on bone mineral density in hemodialysis patients with secondary hyperparathyroidism: possible usefulness of preoperative determination of parathyroid hormone level for prediction of bone regain. (2003) (29)
- Acute-onset hypomagnesemia-induced hypocalcemia caused by the refractoriness of bones and renal tubules to parathyroid hormone (2011) (29)
- Retinoic acid induces osteoclast-like cell formation by directly acting on hemopoietic blast cells and stimulates osteopontin mRNA expression in isolated osteoclasts. (1995) (29)
- Calcitonin inhibits osteopontin mRNA expression in isolated rabbit osteoclasts. (1994) (29)
- Effects of ascorbic acid on alkaline phosphatase activity and hormone responsiveness in the osteoblastic osteosarcoma cell line UMR-106 (1986) (29)
- Second messenger signaling of PTH- and PTHRP-stimulated osteoclast-like cell formation from hemopoietic blast cells. (1993) (28)
- Efficacy and Safety of Risedronate in Osteoporosis Subjects with Comorbid Diabetes, Hypertension, and/or Dyslipidemia: A Post Hoc Analysis of Phase III Trials Conducted in Japan (2015) (28)
- The threshold of bone mineral density for vertebral fractures in female patients with primary hyperparathyroidism. (2005) (28)
- DPP-4 Inhibitors Improve Liver Dysfunction in Type 2 Diabetes Mellitus (2014) (28)
- Effect of low-dose of recombinant human growth hormone on bone metabolism in elderly women with osteoporosis. (2002) (28)
- Primary Aldosteronism as a Risk Factor for Vertebral Fracture (2017) (27)
- Short-term effects of glucocorticoid therapy on biochemical markers of bone metabolism in Japanese patients: a prospective study (2008) (27)
- Serum 25-hydroxyvitamin D level as an independent determinant of quality of life in osteoporosis with a high risk for fracture. (2014) (27)
- Expression of parathyroid hormone‐related protein (PTHrP) in multiple myeloma (2002) (27)
- Once-weekly teriparatide reduces the risk of vertebral fracture in patients with various fracture risks: subgroup analysis of the Teriparatide Once-Weekly Efficacy Research (TOWER) trial (2014) (27)
- Baseline serum total adiponectin level is positively associated with changes in bone mineral density after 1-year treatment of type 2 diabetes mellitus. (2010) (27)
- Direct involvement of cAMP-dependent protein kinase in the regulation of alkaline phosphatase activity by parathyroid hormone (PTH) and PTH-related peptide in osteoblastic UMR-106 cells. (1994) (26)
- FAM210A is a novel determinant of bone and muscle structure and strength (2018) (26)
- Effects of Treatment With Risedronate and Alfacalcidol on Progression of Atherosclerosis in Postmenopausal Women With Type 2 Diabetes Mellitus Accompanied With Osteoporosis (2010) (26)
- Combined effects of dexamethasone and 1,25-dihydroxyvitamin D3 on parathyroid hormone secretion in cultured bovine parathyroid cells. (1989) (25)
- A Paranasal Tumor Associated With Tumor‐Induced Osteomalacia (2006) (25)
- Bazedoxifene Ameliorates Homocysteine-Induced Apoptosis and Accumulation of Advanced Glycation End Products by Reducing Oxidative Stress in MC3T3-E1 Cells (2017) (25)
- Trial to predict malignancy of affected parathyroid glands in primary hyperparathyroidism. (2003) (25)
- Association between the risk of falls and osteoporotic fractures in patients with type 2 diabetes mellitus. (2017) (25)
- Asymmetric dimethylarginine as a risk factor for cardiovascular disease in Japanese patients with type 2 diabetes mellitus (2011) (24)
- Involvement of dual signal transduction systems in the stimulation of osteoclast-like cell formation by parathyroid hormone and parathyroid hormone-related peptide. (1993) (24)
- Osteoporosis and vertebral fracture are associated with deterioration of activities of daily living and quality of life in patients with type 2 diabetes mellitus (2018) (24)
- Elevated Serum Pentosidine and Decreased Serum IGF-I Levels are Associated with Loss of Muscle Mass in Postmenopausal Women with Type 2 Diabetes Mellitus. (2015) (24)
- Advanced Glycation End Product 3 (AGE3) Increases Apoptosis and the Expression of Sclerostin by Stimulating TGF-β Expression and Secretion in Osteocyte-Like MLO-Y4-A2 Cells (2017) (24)
- Vertebral fracture risk after once-weekly teriparatide injections: follow-up study of Teriparatide Once-Weekly Efficacy Research (TOWER) trial (2013) (23)
- BMP/Wnt antagonists are upregulated by dexamethasone in osteoblasts and reversed by alendronate and PTH: Potential therapeutic targets for glucocorticoid-induced osteoporosis (2009) (23)
- Vitamin D status affects osteopenia in postmenopausal patients with primary hyperparathyroidism. (2008) (22)
- Prevalent vertebral fracture is dominantly associated with spinal microstructural deterioration rather than bone mineral density in patients with type 2 diabetes mellitus (2019) (22)
- Constitutive c‐fos expression in osteoblastic MC3T3‐E1 cells stimulates osteoclast maturation and osteoclastic bone resorption (1994) (22)
- Reduced muscle mass and accumulation of visceral fat are independently associated with increased arterial stiffness in postmenopausal women with type 2 diabetes mellitus. (2016) (22)
- Comparison of concurrent treatment with vitamin K2 and risedronate compared with treatment with risedronate alone in patients with osteoporosis: Japanese Osteoporosis Intervention Trial-03 (2017) (21)
- Role of interleukin-6 and prostaglandins in the effect of monocyte-conditioned medium on osteoclast formation. (1994) (21)
- Late-onset isolated adrenocorticotropic hormone deficiency caused by nivolumab: a case report (2019) (21)
- Calcitonin directly acts on mouse osteoblastic MC3T3-E1 cells to stimulate mRNA expression of c-fos, insulin-like growth factor-1 and osteoblastic phenotypes (type 1 collagen and osteocalcin). (1994) (21)
- Body composition and vertebral fracture risk in female patients treated with glucocorticoid (2005) (21)
- Rosuvastatin increased serum osteocalcin levels independent of its serum cholesterol-lowering effect in patients with type 2 diabetes and hypercholesterolemia. (2009) (20)
- Osteosarcoma in a pregnant patient with McCune-Albright syndrome. (2009) (20)
- Glucocorticoid Excess Affects Cortical Bone Geometry in Premenopausal, but not Postmenopausal, Women (2008) (20)
- Familial Hypocalciuric Hypercalcemia Caused by an R648stop Mutation in the Calcium‐Sensing Receptor Gene (2002) (20)
- Analysis of factors affecting increase in bone mineral density at lumbar spine by bisphosphonate treatment in postmenopausal osteoporosis (2008) (20)
- Meprin is predominantly involved in parathyroid hormone degradation by the microvillar membranes of rat kidney. (1994) (20)
- The usefulness of bone metabolic indices for the prediction of changes in bone mineral density after parathyroidectomy in patients with primary hyperparathyroidism. (2006) (20)
- Vitamin D receptor genotype is associated with cortical bone loss in Japanese patients with primary hyperparathyroidism. (1998) (20)
- Role of Smad3, acting independently of transforming growth factor‐β, in the early induction of Wnt‐β‐catenin signaling by parathyroid hormone in mouse osteoblastic cells (2009) (20)
- Serum insulin-like growth factor-I is negatively associated with serum adiponectin in type 2 diabetes mellitus. (2011) (20)
- Phloretin Promotes Adipogenesis via Mitogen-Activated Protein Kinase Pathways in Mouse Marrow Stromal ST2 Cells (2018) (19)
- Parathyroid hormone upregulates BMP-2 mRNA expression through mevalonate kinase and Rho kinase inhibition in osteoblastic MC3T3-E1 cells. (2009) (19)
- Activation of AMP-activated protein kinase decreases receptor activator of NF-κB ligand expression and increases sclerostin expression by inhibiting the mevalonate pathway in osteocytic MLO-Y4 cells. (2016) (19)
- Purification of meprin from human kidney and its role in parathyroid hormone degradation. (1994) (19)
- Design of a pragmatic approach to evaluate the effectiveness of concurrent treatment for the prevention of osteoporotic fractures (2011) (18)
- Glucose uptake inhibition decreases expressions of receptor activator of nuclear factor-kappa B ligand (RANKL) and osteocalcin in osteocytic MLO-Y4-A2 cells. (2018) (18)
- Interleukin-1beta stimulates transendothelial mobilization of human peripheral blood mononuclear cells with a potential to differentiate into osteoclasts in the presence of osteoblasts. (2001) (18)
- Low skeletal muscle mass is associated with the risk of all-cause mortality in patients with type 2 diabetes mellitus (2019) (18)
- Changes in bone mineral density, bone turnover markers, and vertebral fracture risk reduction with once weekly teriparatide (2014) (18)
- Effects of intensive glycemic control on serum levels of insulin-like growth factor-I and dehydroepiandrosterone sulfate in Type 2 diabetes mellitus (2011) (18)
- Association between parathyroid hormone (PTH)/PTH-related peptide receptor gene polymorphism and the extent of bone mass reduction in primary hyperparathyroidism. (2000) (17)
- Fracture risk is increased by the complication of hypertension and treatment with calcium channel blockers in postmenopausal women with type 2 diabetes (2013) (17)
- Internal Tandem Duplication Mutations in FLT3 Gene Augment Chemotaxis to Cxcl12 Protein by Blocking the Down-regulation of the Rho-associated Kinase via the Cxcl12/Cxcr4 Signaling Axis* (2014) (17)
- Assessment using serum insulin-like growth factor-I and bone mineral density is useful for detecting prevalent vertebral fractures in patients with type 2 diabetes mellitus (2018) (17)
- Decreased Serum Insulin-like Growth Factor-I is a Risk Factor for Non-vertebral Fractures in Diabetic Postmenopausal Women (2017) (17)
- The Levels of Somatostatin Receptors in Causative Tumors of Oncogenic Osteomalacia Are Insufficient for Their Agonist to Normalize Serum Phosphate Levels (2010) (17)
- A case of magnesium deficiency associated with insufficient parathyroid hormone action and severe osteoporosis. (2007) (17)
- 24-Month Open-Label Teriparatide Once-Weekly Efficacy Research Trial Examining Bone Mineral Density in Subjects with Primary Osteoporosis and High Fracture Risk (2017) (16)
- Effects of uremic toxin p-cresol on proliferation, apoptosis, differentiation, and glucose uptake in 3T3-L1 cells. (2014) (16)
- Role of dual signal transduction systems in the stimulation of bone resorption by parathyroid hormone-related peptide. The direct involvement of cAMP-dependent protein kinase. (1993) (16)
- Long-term efficacy and safety of vildagliptin add-on therapy in type 2 diabetes mellitus with insulin treatment. (2017) (16)
- Prospective short-term effects of glucocorticoid treatment on glucose and lipid metabolism in Japanese. (2010) (15)
- Effect of 17 beta-estradiol on the proliferation of osteoblastic MC3T3-E1 cells via human monocytes. (1991) (15)
- Evaluation of changes in bone density and biochemical parameters after parathyroidectomy in primary hyperparathyroidism. (2000) (15)
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- The participation of the activation of cAMP-dependent protein kinase in cytosolic acidification by parathyroid hormone (PTH) and PTH-related peptide in osteoblastic osteosarcoma cells. (1992) (0)
- [Medical practice and problem of osteoporosis management by physicians]. (2007) (0)
- Parathyroid disorder and calcium metabolism abnormality. II. Disease state and treatment. 1. Hypercalcemic disease. 1) Primary hyperparathyroidism. (1999) (0)
- [New methods for the evaluation of bone quality. The importance of assessing bone quality.] (2017) (0)
- SUN-412 Graves’ Disease Displayed as a Risk Factor of Vertebral Fracture Even in Premenopausal Women (2020) (0)
- Undercarboxylated osteocalcin/osteocalcin ratio is negatively associated with hyperglycemic conditions, but not with the presence of vertebral fractures, in patients with type 2 diabetes (2009) (0)
- [Treatment of osteoporosis: Vitamin D and calcium preparations]. (2005) (0)
- Signal transduction mechanisms of parathyroid hormone- and parathyroid hormone-related-peptide-stimulated osteoclast-like cell formation from hemopoietic blast cells. (1995) (0)
- Association of n-3 Polyunsaturated Fatty Acid Intake with Bone Mineral Density in Postmenopausal Women (2013) (0)
- Relationship Between Changes in Serum Levels of Intact Parathyroid Hormone and Sclerostin After a Single Dose of Zoledronic Acid: Results of a Phase 1 Pharmacokinetic Study (2021) (0)
- Short title: Osteocalcin and Atherosclerosis (2008) (0)
- Fracture Risk in Diabetes (2016) (0)
- A Case of Primary Hyperparathyroidism with Marked Pancreatic Calcification (1984) (0)
- Treatment of osteopenia secondary to primary hyperparathyroidism. (2000) (0)
- Modulators of Fam210a and Roles of Fam210a in the Function of Myoblasts (2020) (0)
- Vitamin D Receptor Genotype Bone Loss in Japanese Patients Hyperparathyroidism Is Associated with Cort with Primary ica (2006) (0)
- Kobe University Repository : Kernel タイトル Tit le Smad 3 Different ly Affects Osteoblast Different iat ion Depending upon its Different iat ion Stage 著者 (2018) (0)
- Sibling Cases of Multiple Endocrine Neoplasia Type 1 (MEN1) Appearing in a Family with Epilepsy (2006) (0)
- Osteocalcin secretion Osteoporosis Fracture Osteocalcin Adiponectin Osteocalcin Adiponectin secretion Fat accumulation Insulin resistance Diabetes mellitus Atherosclerosis Cardiovascular disease Adiponectin (2012) (0)
- [Epidemiology of parathyroid tumor]. (2011) (0)
- Postmenopausal women with mild to moderate renal dysfunction are at increased risk for bone loss and vertebral fractures (2009) (0)
- [Case of osteomalacia due to intravenous saccharated ferric oxide]. (1998) (0)
- [Bone and calcium metabolism in life-style related diseases]. (2016) (0)
- [109th Scientific Meeting of the Japanese Society of Internal Medicine: educational lecture: 1. Progress in the treatment of osteoporosis]. (2012) (0)
- Contents Vol. 85, 2000 (2000) (0)
- [Senile osteoporosis]. (2005) (0)
- [Significance of bone mass measurement in glucocorticoid-induced osteoporosis]. (2002) (0)
- Diabetes and Osteoporosis (2018) (0)
- Association of leukocyte subtype counts with chronic inflammation and atherosclerosis in type 2 diabetes mellitus (2016) (0)
- [Age-related changes in bone structure using peripheral quantitative computed tomography]. (2006) (0)
- [Process in development of PTH, an awaited bone-density conservation agent]. (2012) (0)
- Effect of ascorbic acid deficiency on calcium metabolism in bone of rat with hereditary defect in L-ascorbic acid biosynthesis (1989) (0)
- Local Therapy of Natural Interferon-α Directry to Involved Sternal Bone in a Patient with Multiple Myeloma (1994) (0)
- Efficacy and Safety of Risedronate in Osteoporosis Subjects with Comorbid Diabetes, Hypertension, and/or Dyslipidemia: A Post Hoc Analysis of Phase III Trials Conducted in Japan (2015) (0)
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What Schools Are Affiliated With Toshitsugu Sugimoto?
Toshitsugu Sugimoto is affiliated with the following schools:
