Tracey Gloster
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British biochemist
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Tracey Glosterbiology Degrees
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Biochemistry
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Biology
Tracey Gloster's Degrees
- PhD Biochemistry University of Oxford
Why Is Tracey Gloster Influential?
(Suggest an Edit or Addition)According to Wikipedia, Tracey Maureen Gloster is a chemist at the University of St Andrews UK. Her research interests are in structural biology, chemical biology, glycobiology and carbohydrate processing enzymes. Education Gloster studied biochemistry at University of Warwick, graduating in 2002 and then moved to University of York where she was awarded a PhD in chemistry in 2005 for research supervised by Gideon Davies.
Tracey Gloster's Published Works
Published Works
- Recent structural insights into the expanding world of carbohydrate-active enzymes. (2005) (294)
- Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells (2011) (252)
- Glycosidase inhibition: assessing mimicry of the transition state (2009) (184)
- The Mechanisms by Which Family 10 Glycoside Hydrolases Bind Decorated Substrates* (2004) (174)
- Developing inhibitors of glycan processing enzymes as tools for enabling glycobiology. (2012) (154)
- Iminosugar glycosidase inhibitors: structural and thermodynamic dissection of the binding of isofagomine and 1-deoxynojirimycin to beta-glucosidases. (2003) (136)
- Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes. (2018) (128)
- Advances in understanding glycosyltransferases from a structural perspective (2014) (116)
- Structural snapshots of the reaction coordinate for O-GlcNAc transferase (2012) (114)
- Characterization and Three-dimensional Structures of Two Distinct Bacterial Xyloglucanases from Families GH5 and GH12* (2007) (114)
- Glycosidase inhibition: an assessment of the binding of 18 putative transition-state mimics. (2007) (113)
- Structure and Activity of Two Metal Ion-dependent Acetylxylan Esterases Involved in Plant Cell Wall Degradation Reveals a Close Similarity to Peptidoglycan Deacetylases* (2006) (112)
- Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function (2009) (111)
- How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity (2012) (105)
- Molecular basis for trehalase inhibition revealed by the structure of trehalase in complex with potent inhibitors. (2007) (97)
- Insights into O-Linked N-Acetylglucosamine ([0-9]O-GlcNAc) Processing and Dynamics through Kinetic Analysis of O-GlcNAc Transferase and O-GlcNAcase Activity on Protein Substrates* (2012) (93)
- A viral ring nuclease anti-CRISPR subverts type III CRISPR immunity (2019) (82)
- Divergence of Catalytic Mechanism within a Glycosidase Family Provides Insight into Evolution of Carbohydrate Metabolism by Human Gut Flora (2008) (76)
- Total syntheses of casuarine and its 6-O-alpha-glucoside: complementary inhibition towards glycoside hydrolases of the GH31 and GH37 families. (2009) (76)
- Elevation of Global O-GlcNAc in Rodents Using a Selective O-GlcNAcase Inhibitor Does Not Cause Insulin Resistance or Perturb Glucohomeostasis (2010) (75)
- Structural and Biochemical Analysis of Cellvibrio japonicus Xylanase 10C (2004) (73)
- Structural and mechanistic insight into N-glycan processing by endo-α-mannosidase (2012) (67)
- Structure and mechanism of a Type III CRISPR defence DNA nuclease activated by cyclic oligoadenylate (2019) (65)
- Mechanism, Structure, and Inhibition of O-GlcNAc Processing Enzymes. (2010) (61)
- Structural studies of the beta-glycosidase from Sulfolobus solfataricus in complex with covalently and noncovalently bound inhibitors. (2004) (59)
- An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity (2020) (54)
- Inhibition of O-GlcNAcase Using a Potent and Cell-Permeable Inhibitor Does Not Induce Insulin Resistance in 3T3-L1 Adipocytes (2010) (53)
- Glycosidase inhibition by ring-modified castanospermine analogues: tackling enzyme selectivity by inhibitor tailoring. (2009) (46)
- Structural basis for cyclophellitol inhibition of a β-glucosidase (2007) (43)
- Metabolic Inhibitors of O‐GlcNAc Transferase That Act In Vivo Implicate Decreased O‐GlcNAc Levels in Leptin‐Mediated Nutrient Sensing (2018) (41)
- Signature active site architectures illuminate the molecular basis for ligand specificity in family 35 carbohydrate binding module. (2010) (40)
- Structural, kinetic, and thermodynamic analysis of glucoimidazole-derived glycosidase inhibitors. (2006) (38)
- Structural, Thermodynamic, and Kinetic Analyses of Tetrahydrooxazine-derived Inhibitors Bound to β-Glucosidases* (2004) (37)
- Insights into the structural determinants of cohesin-dockerin specificity revealed by the crystal structure of the type II cohesin from Clostridium thermocellum SdbA. (2005) (35)
- Casuarine-6-O-alpha-D-glucoside and its analogues are tight binding inhibitors of insect and bacterial trehalases. (2010) (34)
- Molecular Basis for β‐Glucosidase Inhibition by Ring‐Modified Calystegine Analogues (2008) (34)
- Inhibition of O-GlcNAcase Using a Potent and Cell-Permeable Inhibitor Does Not Induce Insulin Resistance in 3T3-L1 Adipocytes (2010) (34)
- The Development of Selective Inhibitors of NagZ: Increased Susceptibility of Gram-Negative Bacteria to β-Lactams (2013) (30)
- Dissection of Conformationally Restricted Inhibitors Binding to a β‐Glucosidase (2006) (27)
- Structural Snapshots for Mechanism‐Based Inactivation of a Glycoside Hydrolase by Cyclopropyl Carbasugars (2016) (26)
- Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level (2018) (26)
- Atomic resolution analyses of the binding of xylobiose-derived deoxynojirimycin and isofagomine to xylanase Xyn10A. (2004) (25)
- Production of α-L-iduronidase in maize for the potential treatment of a human lysosomal storage disease (2012) (23)
- A xylobiose-derived isofagomine lactam glycosidase inhibitor binds as its amide tautomer. (2003) (22)
- The CRISPR ancillary effector Can2 is a dual-specificity nuclease potentiating type III CRISPR defence (2021) (22)
- Structural insight into the mechanism of streptozotocin inhibition of O-GlcNAcase. (2009) (22)
- Characterization and downstream mannose phosphorylation of human recombinant α-L-iduronidase produced in Arabidopsis complex glycan-deficient (cgl) seeds (2013) (19)
- Development of inhibitors as research tools for carbohydrate-processing enzymes. (2012) (17)
- Inhibition of a bacterial O-GlcNAcase homologue by lactone and lactam derivatives: structural, kinetic and thermodynamic analyses (2011) (15)
- Tetramerisation of the CRISPR ring nuclease Crn3/Csx3 facilitates cyclic oligoadenylate cleavage (2020) (15)
- 6''-Azido-6''-deoxy-UDP-N-acetylglucosamine as a glycosyltransferase substrate. (2011) (14)
- Mechanism of Human Nucleocytoplasmic Hexosaminidase D (2016) (13)
- The Enzymatic Degradation of Heparan Sulfate. (2017) (11)
- Structural basis for cyclophellitol inhibition of a beta-glucosidase. (2007) (11)
- Sialidase and Sialyltransferase Inhibitors: Targeting Pathogenicity and Disease (2021) (10)
- Linear Eyring Plots Conceal a Change in the Rate-Limiting Step in an Enzyme Reaction (2018) (9)
- d-Glucosylated Derivatives of Isofagomine and Noeuromycin and Their Potential as Inhibitors of β-Glycoside Hydrolases (2007) (9)
- Analysis of the product streams obtained on butanosolv pretreatment of draff (2020) (8)
- Exploitation of carbohydrate processing enzymes in biocatalysis. (2020) (6)
- Casuarine-6-O-α-D-glucoside and Its Analogues Are Tight Binding Inhibitors of Insect and Bacterial Trehalases. (2010) (6)
- New Irreversible α‐l‐Iduronidase Inhibitors and Activity‐Based Probes (2018) (6)
- Common inhibition of both beta-glucosidases and beta-mannosidases by isofagomine lactam reflects different conformational itineraries for pyranoside hydrolysis. (2004) (5)
- Insights into O-GlcNAc processing and dynamics through kinetic analysis of O-GlcNAc transferase and O-GlcNAcase activity on protein substrates* (2012) (4)
- Tetramerisation of the CRISPR ring nuclease Csx3 facilitates cyclic oligoadenylate cleavage (2020) (3)
- Dissection of conformationally restricted inhibitors binding to a beta-glucosidase. (2006) (2)
- Dissecting the Mechanism of (R)-3-Hydroxybutyrate Dehydrogenase by Kinetic Isotope Effects, Protein Crystallography, and Computational Chemistry (2020) (2)
- Structure, dynamics, and molecular inhibition of the Staphylococcus aureus m1A22-tRNA methyltransferase TrmK (2022) (1)
- Author Correction: Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level (2018) (1)
- Kinetic and Structural Characterization of Sialidases (Kdnases) from Ascomycete Fungal Pathogens. (2021) (0)
- Structure of KDNase from Trichophyton Rubrum in complex with 2-keto-3-deoxynononic acid (2021) (0)
- Beta-glycosidase from Sulfolobus solfataricus in complex with phenethyl-substituted glucoimidazole (2006) (0)
- Structure and mechanism of a Type III CRISPR defence DNA nuclease activated by cyclic oligoadenylate (2020) (0)
- The structure of a family 4 acetyl xylan esterase from Clostridium thermocellum in complex with a magnesium ion. (2006) (0)
- Beta-glucosidase from Thermotoga maritima in complex with glucoimidazole (2006) (0)
- Structure of GH36 alpha-galactosidase from Thermotoga maritima in complex with a hydrolysed cyclopropyl carbasugar. (2016) (0)
- Native structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron (2008) (0)
- Structure of the GH99 endo-alpha-mannosidase from Bacteroides thetaiotaomicron (2012) (0)
- Crystal structure of human O-GlcNAc Transferase with UDP-5SGlcNAc and a peptide substrate (2012) (0)
- Alpha-galactosidase from Thermotoga maritima in complex with hydrolysed cyclohexene-based carbasugar mimic of galactose (2018) (0)
- Beta-glucosidase from Thermotoga maritima in complex with castanospermine (2006) (0)
- ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHAERENS IN COMPLEX WITH CELLOBIO DERIVED-TETRAHYDROOXAZINE (2004) (0)
- Structure of the GH99 endo-alpha-mannosidase from Bacteroides xylanisolvens (2012) (0)
- Author response: Tetramerisation of the CRISPR ring nuclease Crn3/Csx3 facilitates cyclic oligoadenylate cleavage (2020) (0)
- Structure of the GH99 endo-alpha-mannosidase from Bacteroides xylanisolvens in complex with glucose-1,3-deoxymannojirimycin and alpha-1,2-mannobiose (2012) (0)
- Structure of the GH99 endo-alpha-mannosidase from Bacteroides xylanisolvens in complex with Glucose-1,3-deoxymannojirimycin (2012) (0)
- Structure of KDNase from Trichophyton Rubrum in complex with 2,3-didehydro-2,3-dideoxy-D-glycero-D-galacto-nonulosonic acid. (2021) (0)
- Structure of Csx3/Crn3 from Archaeoglobus fulgidus in complex with cyclic tetra-adenylate (cA4) (2020) (0)
- Crystal structure of human O-GlcNAc Transferase with UDP and a thioglycopeptide (2012) (0)
- Alpha-galactosidase from Thermotoga maritima in complex with cyclohexene-based carbasugar mimic of galactose (2018) (0)
- Beta-glucosidase from Thermotoga maritima in complex with noeuromycin (2006) (0)
- Apo structure of KDNase from Trichophyton Rubrum (2021) (0)
- Beta-glucosidase from Thermotoga maritima in complex with methoxycarbonyl-substituted glucoimidazole (2006) (0)
- Beta-glucosidase from Thermotoga maritima in complex with N-octyl-5- deoxy-6-oxa-N-(thio)carbamoylcalystegine (2008) (0)
- Carbohydrate binding module CBM66 from Bacillus subtilis (2012) (0)
- Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level (2018) (0)
- Beta-glycosidase from Sulfolobus solfataricus in complex with glucoimidazole (2006) (0)
- Xylanase10C (mutant E385A) from Cellvibrio japonicus in complex with xylopentaose (2003) (0)
- Structure of the GH99 endo-alpha-mannosidase from Bacteroides xylanisolvens in complex with glucose-1,3-isofagomine (2012) (0)
- Structure of family 1 beta-glucosidase from Thermotoga maritima in complex with 3-imino-2-oxa-(+)-8-epi-castanospermine (2009) (0)
- Structure of KDNase from Aspergillus Terrerus in complex with 2-keto-3-deoxynononic acid (2021) (0)
- Structure of beta-glycosidase from Sulfolobus solfataricus (2004) (0)
- Xylanase Xyn10A from Streptomyces lividans in complex with xylobio-deoxynojirimycin at pH 5.8 (2004) (0)
- Structure of a Type III CRISPR defence DNA nuclease activated by cyclic oligoadenylate (2020) (0)
- Crystal structure of (R)-3-hydroxybutyrate dehydrogenase from Psychrobacter arcticus complexed with NAD+ and acetoacetate (2020) (0)
- Beta-glucosidase from Thermotoga maritima in complex with methyl acetic acid-substituted glucoimidazole (2006) (0)
- Crystal structure of human O-GlcNAc Transferase with UDP-5SGlcNAc (2012) (0)
- Family 1 b-glucosidase from Thermotoga maritima (2003) (0)
- Apo structure of KDNase from Aspergillus Terrerus (2021) (0)
- Native family 5 xyloglucanase from Paenibacillus pabuli (2007) (0)
- Structure of Can2 from Sulfobacillus thermosulfidooxidans in complex with cyclic tetra-adenylate (cA4) (2021) (0)
- Beta-glucosidase from Thermotoga maritima in complex with deoxynojirimycin (2006) (0)
- Family 37 trehalase from Escherichia coli in complex with 1- thiatrehazolin (2007) (0)
- Xylanase Xyn10B mutant (E262S) from Cellvibrio mixtus in complex with xylopentaose (2003) (0)
- Family 35 carbohydrate binding module from Clostridium thermocellum (2010) (0)
- Structural and Biochemical Analysis of Cellvibrio japonicus Xylanase 10C HOW VARIATION IN SUBSTRATE-BINDING CLEFT INFLUENCES THE CATALYTIC PROFILE OF FAMILY GH-10 XYLANASES*□S (2004) (0)
- Family 5 xyloglucanase from Paenibacillus pabuli in complex with ligand (2007) (0)
- Family 1 b-glucosidase from Thermotoga maritima in complex with tetrahydrooxazine (2004) (0)
- Structure of KDNase from Aspergillus Terrerus in complex with 2,3-difluoro-2-keto-3-deoxynononic acid (2021) (0)
- Family 5 endoglucanase Cel5A from Bacillus agaradhaerens in complex with cellobio-derived noeuromycin (2007) (0)
- Elevation of Global O-GlcNAc in Rodents Using a Selective O-GlcNAcase Inhibitor Does Not Cause Insulin Resistance or Perturb Glucohomeostasis (2010) (0)
- Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine (2008) (0)
- Selenomethionine derivative of the GH99 endo-alpha-mannosidase from Bacteroides thetaiotaomicron (2012) (0)
- cazy_webscraper: For creating a local CAZy database (2021) (0)
- Structure of beta-glycosidase from Sulfolobus solfataricus in complex with 2-deoxy-2-fluoro-galactose (2004) (0)
- A viral anti-CRISPR subverts type III CRISPR immunity by rapid degradation of cyclic oligoadenylate (2019) (0)
- Family 1 b-glucosidase from Thermotoga maritima in complex with isofagomine lactam (2004) (0)
- Clostridium thermocellum CBM35 in complex with delta-4,5- anhydrogalacturonic acid (2009) (0)
- Alpha-galactosidase from Thermotoga maritima in complex with cyclohexene-based carbasugar mimic of galactose covalently linked to the nucleophile (2018) (0)
- Xylanase Xyn10A from Streptomyces lividans in complex with xylobio-isofagomine at pH 5.8 (2004) (0)
- Beta-glucosidase from Thermotoga maritima in complex with galacto- hydroximolactam (2006) (0)
- Crystal structure of human O-GlcNAc Transferase in complex with UDP and a glycopeptide (2012) (0)
- cazy_webscraper: local compilation and interrogation of comprehensive CAZyme datasets (2022) (0)
- Native family 12 xyloglucanase from Bacillus licheniformis (2007) (0)
- Beta-glucosidase from Thermotoga maritima in complex with azafagomine (2006) (0)
- Native structure of a family 35 carbohydrate binding module from Clostridium thermocellum (2009) (0)
- Crystal structure of (R)-3-hydroxybutyrate dehydrogenase from Psychrobacter arcticus complexed with NAD+ and 3-oxovalerate (2020) (0)
- Xylanase Xyn10B mutant (E262S) from Cellvibrio mixtus in complex with 4-O-methyl glucuronic acid (2003) (0)
- Family 37 trehalase from Escherichia coli in complex with validoxylamine (2007) (0)
- Beta-glucosidase from Thermotoga maritima in complex with cyclophellitol (2007) (0)
- Comprehensive evaluation of CAZyme prediction tools in fungal and bacterial species (2021) (0)
- An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity (2020) (0)
- Beta-glucosidase from Thermotoga maritima in complex with phenethyl- substituted glucoimidazole (2006) (0)
- Native xylanase10C from Cellvibrio japonicus (2003) (0)
- Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin (2008) (0)
- Structure of beta-glycosidase from Sulfolobus solfataricus in complex with 2-deoxy-2-fluoro-glucose (2004) (0)
- Xylanase Xyn10a from Streptomyces lividans in complex with xylobio-deoxynojirimycin at pH 7.5 (2004) (0)
- Beta-glucosidase from Thermotoga maritima in complex with calystegine B2 (2006) (0)
- Xylanase Xyn10A from Streptomyces lividans in complex with xylobio-isofagomine lactam (2003) (0)
- Structure of family 37 trehalase from Escherichia coli in complex with a casuarine-6-O-a-D-glucoside analogue (2010) (0)
- Family 12 xyloglucanase from Bacillus licheniformis in complex with ligand (2007) (0)
- Family 37 trehalase from Escherichia coli in complex with casuarine-6- O-alpha-glucopyranose (2009) (0)
- Beta-glucosidase from Thermotoga maritima in complex with gluco- hydroximolactam (2006) (0)
- Structure of a family 35 carbohydrate binding module from an environmental isolate (2009) (0)
- Xyl-CBM35 in complex with glucuronic acid containing disaccharide. (2009) (0)
- Structure of beta-glycosidase from Sulfolobus solfataricus in complex with D-galactohydroximo-1,5-lactam (2004) (0)
- Structure of GH36 alpha-galactosidase from Thermotoga maritima in complex with intact cyclopropyl-carbasugar. (2016) (0)
- Structure of KDNase from Aspergillus terrerus in complex with 2,3-didehydro-2,3-dideoxy-D-glycero-D-galacto-nonulosonic acid. (2021) (0)
- Structure of the Type II cohesin from Clostridium thermocellum SdbA (2005) (0)
- Structure of the GH99 endo-alpha-mannosidase from Bacteriodes thetaiotaomicron in complex with BIS-TRIS-Propane (2012) (0)
- Alpha-galactosidase mutant D378A from Thermotoga maritima in complex with intact cyclohexene-based carbasugar mimic of galactose with 3,5 difluorophenyl leaving group (2018) (0)
- Author Correction: Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level (2018) (0)
- Structure, dynamics, and inhibition of Staphylococcus aureus m1A22-tRNA methyltransferase (2021) (0)
- Alpha-galactosidase mutant D387A from Thermotoga maritima in complex with intact cyclohexene-based carbasugar mimic of galactose with 2,4-dinitro leaving group (2018) (0)
- Crystal structure of (R)-3-hydroxybutyrate dehydrogenase from Acinetobacter baumannii complexed with NAD+ and 3-oxovalerate (2020) (0)
- CBM35 from Cellvibrio japonicus Abf62 (2009) (0)
- Structure of a family 4 carbohydrate esterase from Bacillus anthracis (2006) (0)
- Beta-glucosidase from Thermotoga maritima in complex with phenylaminomethyl-derived glucoimidazole (2006) (0)
- Xylanase Xyn10B mutant (E262S) from Cellvibrio mixtus in complex with arabinofuranose alpha 1,3 linked to xylotriose (2003) (0)
- Structure of apo structure of GH36 alpha-galactosidase from Thermotoga maritima (2016) (0)
- Xylanase Xyn10a from Streptomyces lividans in complex with xylobio-isofagomine at pH 7.5 (2004) (0)
- Family 4 carbohydrate esterase from Streptomyces lividans in complex with acetate (2006) (0)
- Structure of GH36 alpha-galactosidase from Thermotoga maritima in a covalent complex with a cyclopropyl carbasugar. (2016) (0)
- Structure of a family 26 lichenase in complex with noeuromycin (2007) (0)
- Structure of Trichophyton Rubrum KDNase in complex with 2,3-difluoro-KDN (2021) (0)
- Beta-glucosidase from Thermotoga maritima in complex with carboxylate- substituted glucoimidazole (2006) (0)
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