Tracey Rouault
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American rheumatologist and physician-scientist
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Philosophy
Tracey Rouault's Degrees
- Doctorate Medicine Johns Hopkins University
- PhD Immunology Johns Hopkins University
Why Is Tracey Rouault Influential?
(Suggest an Edit or Addition)According to Wikipedia, Tracey Ann Rouault is an American rheumatologist and physician-scientist who researches mammalian iron-sulfur proteins. Rouault is a senior investigator at the Eunice Kennedy Shriver National Institute of Child Health and Human Development and she heads the section on human iron metabolism.
Tracey Rouault's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Regulating the fate of mRNA: The control of cellular iron metabolism (1993) (1175)
- The role of iron regulatory proteins in mammalian iron homeostasis and disease (2006) (904)
- A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression. (2005) (620)
- Iron-responsive elements: regulatory RNA sequences that control mRNA levels and translation. (1988) (604)
- Identification of the iron-responsive element for the translational regulation of human ferritin mRNA. (1987) (467)
- Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice (2001) (461)
- Iron–sulphur cluster biogenesis and mitochondrial iron homeostasis (2005) (383)
- Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis (2004) (375)
- Iron metabolism in the CNS: implications for neurodegenerative diseases (2013) (366)
- Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway. (2010) (360)
- Sedimentation equilibrium analysis of protein interactions with global implicit mass conservation constraints and systematic noise decomposition. (2004) (351)
- Hereditary hemochromatosis. (1993) (333)
- Iron-sulfur cluster biogenesis and human disease. (2008) (332)
- Oxidation-reduction and the molecular mechanism of a regulatory RNA-protein interaction. (1989) (321)
- Iron‐dependent regulation of the divalent metal ion transporter (2001) (305)
- Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: implications for degradation of oxidized proteins. (1998) (295)
- Cellular regulation of the iron-responsive element binding protein: disassembly of the cubane iron-sulfur cluster results in high-affinity RNA binding. (1992) (292)
- Biogenesis of iron-sulfur clusters in mammalian cells: new insights and relevance to human disease (2012) (292)
- Binding of a cytosolic protein to the iron-responsive element of human ferritin messenger RNA. (1988) (285)
- Brain iron metabolism. (2006) (275)
- Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis. (2006) (266)
- A ferroportin transcript that lacks an iron-responsive element enables duodenal and erythroid precursor cells to evade translational repression. (2009) (251)
- Structural relationship between an iron-regulated RNA-binding protein (IRE-BP) and aconitase: Functional implications (1991) (249)
- Regulation of iron metabolism in eukaryotes. (1997) (246)
- Iron on the brain (2001) (243)
- Mutations in iron-sulfur cluster scaffold genes NFU1 and BOLA3 cause a fatal deficiency of multiple respiratory chain and 2-oxoacid dehydrogenase enzymes. (2011) (242)
- Reciprocal control of RNA-binding and aconitase activity in the regulation of the iron-responsive element binding protein: role of the iron-sulfur cluster. (1992) (241)
- Mammalian Tissue Oxygen Levels Modulate Iron-Regulatory Protein Activities in Vivo (2004) (235)
- Iron-sulfur clusters as biosensors of oxidants and iron. (1996) (230)
- Human Iron−Sulfur Cluster Assembly, Cellular Iron Homeostasis, and Disease† (2010) (228)
- Dysfunction of the heme recycling system in heme oxygenase 1-deficient mice: effects on macrophage viability and tissue iron distribution. (2010) (222)
- Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2. (2005) (218)
- Molecular characterization of a second iron-responsive element binding protein, iron regulatory protein 2. Structure, function, and post-translational regulation. (1994) (217)
- Glutaredoxin 5 deficiency causes sideroblastic anemia by specifically impairing heme biosynthesis and depleting cytosolic iron in human erythroblasts. (2010) (216)
- Iron Accumulation in Deep Cortical Layers Accounts for MRI Signal Abnormalities in ALS: Correlating 7 Tesla MRI and Pathology (2012) (213)
- Distinct iron–sulfur cluster assembly complexes exist in the cytosol and mitochondria of human cells (2000) (201)
- A cis-acting element is necessary and sufficient for translational regulation of human ferritin expression in response to iron. (1987) (200)
- Requirements for iron‐regulated degradation of the RNA binding protein, iron regulatory protein 2. (1995) (198)
- Expression of the iron transporter ferroportin in synaptic vesicles and the blood–brain barrier (2004) (197)
- Splice mutation in the iron-sulfur cluster scaffold protein ISCU causes myopathy with exercise intolerance. (2008) (195)
- A regulated RNA binding protein also possesses aconitase activity. (1991) (193)
- Subcellular compartmentalization of human Nfu, an iron–sulfur cluster scaffold protein, and its ability to assemble a [4Fe–4S] cluster (2003) (191)
- Association of pulmonary tuberculosis with increased dietary iron. (2001) (191)
- Iron overload in Africans and African-Americans and a common mutation in the SCL40A1 (ferroportin 1) gene. (2003) (190)
- The glycolytic shift in fumarate-hydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels. (2011) (186)
- Mitochondrial iron chelation ameliorates cigarette-smoke induced bronchitis and emphysema in mice (2015) (177)
- The physiological functions of iron regulatory proteins in iron homeostasis - an update (2014) (176)
- Identification of the ubiquitin–protein ligase that recognizes oxidized IRP2 (2003) (175)
- Structure and dynamics of the iron responsive element RNA: implications for binding of the RNA by iron regulatory binding proteins. (1997) (175)
- Targeting of a human iron-sulfur cluster assembly enzyme, nifs, to different subcellular compartments is regulated through alternative AUG utilization. (1998) (173)
- Dietary iron overload as a risk factor for hepatocellular carcinoma in black africans (1998) (171)
- Iron-sulfur cluster biogenesis in mammalian cells: New insights into the molecular mechanisms of cluster delivery. (2015) (170)
- Cloning of the cDNA encoding an RNA regulatory protein--the human iron-responsive element-binding protein. (1990) (166)
- Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase (2020) (166)
- Molecular Pathways: Fumarate Hydratase-Deficient Kidney Cancer—Targeting the Warburg Effect in Cancer (2013) (165)
- Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression (2018) (164)
- Mammalian iron–sulphur proteins: novel insights into biogenesis and function (2014) (155)
- Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2α. (2013) (151)
- Human ISD11 is essential for both iron-sulfur cluster assembly and maintenance of normal cellular iron homeostasis. (2009) (139)
- Iron-dependent regulation of frataxin expression: implications for treatment of Friedreich ataxia (2008) (136)
- Regulation of interaction of the iron-responsive element binding protein with iron-responsive RNA elements (1989) (134)
- Differences in the RNA binding sites of iron regulatory proteins and potential target diversity. (1996) (134)
- Identification of a Conserved and Functional Iron-responsive Element in the 5′-Untranslated Region of Mammalian Mitochondrial Aconitase* (1996) (132)
- Both human ferredoxins 1 and 2 and ferredoxin reductase are important for iron-sulfur cluster biogenesis. (2012) (132)
- Metabolic regulation of citrate and iron by aconitases: role of iron–sulfur cluster biogenesis (2007) (131)
- The bifunctional iron-responsive element binding protein/cytosolic aconitase: the role of active-site residues in ligand binding and regulation. (1994) (128)
- Transcriptional regulation by iron of the gene for the transferrin receptor (1986) (123)
- Cochaperone binding to LYR motifs confers specificity of iron sulfur cluster delivery. (2014) (121)
- Brain iron homeostasis, the choroid plexus, and localization of iron transport proteins (2009) (119)
- Complete loss of iron regulatory proteins 1 and 2 prevents viability of murine zygotes beyond the blastocyst stage of embryonic development. (2006) (113)
- Clinical Severity and Thermodynamic Effects of Iron-responsive Element Mutations in Hereditary Hyperferritinemia-Cataract Syndrome* (1999) (113)
- Role of hepcidin in murine brain iron metabolism (2009) (113)
- The iron-responsive element binding protein: a method for the affinity purification of a regulatory RNA-binding protein. (1989) (112)
- Ferritin is secreted via 2 distinct nonclassical vesicular pathways. (2018) (111)
- Homeostatic Mechanisms for Iron Storage Revealed by Genetic Manipulations and Live Imaging of Drosophila Ferritin (2007) (109)
- Biogenesis and functions of mammalian iron-sulfur proteins in the regulation of iron homeostasis and pivotal metabolic pathways (2017) (107)
- The iron-responsive element-binding protein: localization of the RNA-binding site to the aconitase active-site cleft. (1994) (105)
- Characterization of mitochondrial ferritin in Drosophila. (2006) (105)
- A model for the structure and functions of iron-responsive elements. (1988) (102)
- A double life: cytosolic aconitase as a regulatory RNA binding protein. (1993) (101)
- Compartment-specific Protection of Iron-Sulfur Proteins by Superoxide Dismutase* (2003) (100)
- Posttranslational stability of the heme biosynthetic enzyme ferrochelatase is dependent on iron availability and intact iron-sulfur cluster assembly machinery. (2010) (94)
- Iron chaperones PCBP1 and PCBP2 mediate the metallation of the dinuclear iron enzyme deoxyhypusine hydroxylase (2014) (93)
- Mutations in LYRM4, encoding iron-sulfur cluster biogenesis factor ISD11, cause deficiency of multiple respiratory chain complexes. (2013) (93)
- Serum transferrin receptors are decreased in the presence of iron overload. (1998) (91)
- Systemic iron metabolism: a review and implications for brain iron metabolism. (2001) (91)
- Renal iron metabolism: transferrin iron delivery and the role of iron regulatory proteins. (2007) (91)
- Evidence of genetic transmission in African iron overload. (1998) (90)
- Hepcidin regulates ferroportin expression and intracellular iron homeostasis of erythroblasts. (2011) (88)
- Metabolic Reprogramming for Producing Energy and Reducing Power in Fumarate Hydratase Null Cells from Hereditary Leiomyomatosis Renal Cell Carcinoma (2013) (86)
- Modification of a free Fe-S cluster cysteine residue in the active iron-responsive element-binding protein prevents RNA binding. (1993) (86)
- Targeting ABL1-mediated oxidative stress adaptation in fumarate hydratase-deficient cancer. (2014) (85)
- Roles of the Mammalian Cytosolic Cysteine Desulfurase, ISCS, and Scaffold Protein, ISCU, in Iron-Sulfur Cluster Assembly* (2006) (83)
- Characterization of the human HSC20, an unusual DnaJ type III protein, involved in iron-sulfur cluster biogenesis. (2010) (83)
- Neuroprotective mechanism of mitochondrial ferritin on 6-hydroxydopamine-induced dopaminergic cell damage: implication for neuroprotection in Parkinson's disease. (2010) (82)
- Erythrocytic ferroportin reduces intracellular iron accumulation, hemolysis, and malaria risk (2018) (81)
- Tempol-mediated activation of latent iron regulatory protein activity prevents symptoms of neurodegenerative disease in IRP2 knockout mice (2008) (75)
- Hemin, chelatable iron, and the regulation of transferrin receptor biosynthesis. (1985) (75)
- The iron-responsive element binding protein: a target for synaptic actions of nitric oxide. (1994) (73)
- Disease-Causing SDHAF1 Mutations Impair Transfer of Fe-S Clusters to SDHB. (2016) (72)
- The iron-responsive element is the single element responsible for iron-dependent translational regulation of ferritin biosynthesis. Evidence for function as the binding site for a translational repressor. (1988) (69)
- Advancements in the pathophysiology of Friedreich's Ataxia and new prospects for treatments. (2007) (69)
- Iron control of erythroid development by a novel aconitase-associated regulatory pathway. (2010) (66)
- Pathogenic Bacteria Prefer Heme (2004) (65)
- Iron regulates the activity of the iron-responsive element binding protein without changing its rate of synthesis or degradation. (1992) (62)
- Cell‐cycle arrest and inhibition of G1 cyclin translation by iron in AFT1‐1up yeast (1998) (61)
- SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery. (2015) (61)
- Acute loss of iron–sulfur clusters results in metabolic reprogramming and generation of lipid droplets in mammalian cells (2018) (61)
- Elevated FGF21 secretion, PGC-1α and ketogenic enzyme expression are hallmarks of iron-sulfur cluster depletion in human skeletal muscle. (2014) (60)
- MRI detection of ferritin iron overload and associated neuronal pathology in iron regulatory protein-2 knockout mice (2003) (59)
- Outlining the Complex Pathway of Mammalian Fe-S Cluster Biogenesis. (2020) (57)
- A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III. (2017) (55)
- Electron tomography of degenerating neurons in mice with abnormal regulation of iron metabolism. (2005) (53)
- Iron Insufficiency Compromises Motor Neurons and Their Mitochondrial Function in Irp2-Null Mice (2011) (53)
- Of Two Cytosolic Aconitases Expressed in Drosophila, Only One Functions as an Iron-regulatory Protein* (2006) (52)
- Iron-sulfur proteins hiding in plain sight. (2015) (52)
- Specific binding of host cell proteins to the 3'-terminal stem-loop structure of rubella virus negative-strand RNA (1991) (51)
- Ferroportin deficiency in erythroid cells causes serum iron deficiency and promotes hemolysis due to oxidative stress. (2018) (51)
- Post-transcriptional regulation of human iron metabolism by iron regulatory proteins. (2002) (51)
- The role of endogenous heme synthesis and degradation domain cysteines in cellular iron-dependent degradation of IRP2. (2003) (50)
- Regulation of intracellular iron metabolism in human erythroid precursors by internalized extracellular ferritin. (1999) (50)
- African iron overload and hepatocellular carcinoma (HA‐7–0–080) (1998) (49)
- Mitochondrial iron overload: causes and consequences. (2016) (48)
- Mitochondrial DNA alterations underlie an irreversible shift to aerobic glycolysis in fumarate hydratase–deficient renal cancer (2021) (48)
- Iron overload in urban Africans in the 1990s (1999) (48)
- Specific high-affinity binding of host cell proteins to the 3' region of rubella virus RNA. (1990) (47)
- Influence of altered transcription on the translational control of human ferritin expression. (1987) (47)
- Wild-type macrophages reverse disease in heme oxygenase 1-deficient mice. (2014) (46)
- Novel Frataxin Isoforms May Contribute to the Pathological Mechanism of Friedreich Ataxia (2012) (45)
- The indispensable role of mammalian iron sulfur proteins in function and regulation of multiple diverse metabolic pathways (2019) (44)
- Iron misregulation and neurodegenerative disease in mouse models that lack iron regulatory proteins (2015) (43)
- Fe-S cofactors in the SARS-CoV-2 RNA-dependent RNA polymerase are potential antiviral targets (2021) (43)
- Traditional beer consumption and the iron status of spouse pairs from a rural community in Zimbabwe. (1997) (42)
- Hepatic iron overload in alcoholic liver disease: why does it occur and what is its role in pathogenesis? (2003) (42)
- An IRP-like protein from Plasmodium falciparum binds to a mammalian iron-responsive element. (2001) (42)
- Erythropoiesis and Iron Sulfur Cluster Biogenesis (2010) (41)
- Non‐transferrin‐bound iron and hepatic dysfunction in African dietary iron overload (1999) (41)
- Iron Regulatory Protein 2 as Iron Sensor (2003) (40)
- Neurochemical investigations of dopamine neuronal systems in iron-regulatory protein 2 (IRP-2) knockout mice. (2005) (39)
- Mammalian iron-sulfur cluster biogenesis: Recent insights into the roles of frataxin, acyl carrier protein and ATPase-mediated transfer to recipient proteins. (2020) (38)
- Expression of Human Frataxin Is Regulated by Transcription Factors SRF and TFAP2 (2010) (37)
- Post-transcriptional regulation of genes of iron metabolism in mammalian cells (1996) (37)
- An iron regulatory-like protein expressed in Plasmodium falciparum displays aconitase activity. (2005) (36)
- Overexpression of iron-responsive element-binding protein and its analytical characterization as the RNA-binding form, devoid of an iron-sulfur cluster. (1994) (35)
- An iron-sulfur cluster plays a novel regulatory role in the iron-responsive element binding protein (1992) (35)
- Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis (2019) (35)
- The inhibition of the iron responsive element RNA-protein interaction by heme does not mimic in vivo iron regulation. (1990) (34)
- Expression of a recombinant IRP-like Plasmodium falciparum protein that specifically binds putative plasmodial IREs. (2003) (34)
- Identification of a Heme-sensing Domain in Iron Regulatory Protein 2* (2004) (34)
- Tissue Specificity of a Human Mitochondrial Disease (2012) (33)
- Identification and characterization of host factor interactions with cis-acting elements of rubella virus RNA. (1994) (32)
- Absence of iron-responsive element-binding protein 2 causes a novel neurodegenerative syndrome. (2019) (32)
- Potential role of iron in repair of inflammatory demyelinating lesions. (2019) (32)
- Numerous Proteins in Mammalian Cells Are Prone to Iron-Dependent Oxidation and Proteasomal Degradation (2002) (31)
- Deletional analysis of the promoter region of the human transferrin receptor gene. (1988) (31)
- Differences in the terminal steps of complement lysis of normal and paroxysmal nocturnal hemoglobinuria red cells. (1978) (31)
- Cytosolic HSC20 integrates de novo iron–sulfur cluster biogenesis with the CIAO1-mediated transfer to recipients (2018) (30)
- SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery. (2016) (30)
- 12 Translational Control of Ferritin (1996) (29)
- How Mammals Acquire and Distribute Iron Needed for Oxygen-Based Metabolism (2003) (29)
- Cell-cycle arrest and inhibition of G1 cyclin translation by iron in AFT1-1(up) yeast. (1998) (29)
- MCV as a guide to phlebotomy therapyfor hemochromatosis (2001) (29)
- The impact of oxidative stress on eukaryotic iron metabolism. (1996) (28)
- The Intestinal Heme Transporter Revealed (2005) (28)
- Iron-sulfur clusters in chemistry and biology (2014) (27)
- Mammalian Fe-S proteins: definition of a consensus motif recognized by the co-chaperone HSC20. (2016) (27)
- Sequence and expression of the murine iron-responsive element binding protein. (1991) (26)
- Ferritin overexpression in Drosophila glia leads to iron deposition in the optic lobes and late-onset behavioral defects (2011) (26)
- TLR-activated repression of Fe-S cluster biogenesis drives a metabolic shift and alters histone and tubulin acetylation. (2018) (26)
- An Ancient Gauge for Iron (2009) (24)
- Manganese targets m‐aconitase and activates iron regulatory protein 2 in AF5 GABAergic cells (2007) (24)
- Behavioral decline and premature lethality upon pan-neuronal ferritin overexpression in Drosophila infected with a virulent form of Wolbachia (2014) (23)
- Insertion mutants in Drosophila melanogaster Hsc20 halt larval growth and lead to reduced iron–sulfur cluster enzyme activities and impaired iron homeostasis (2013) (21)
- Glia maturation factor-γ regulates murine macrophage iron metabolism and M2 polarization through mitochondrial ROS. (2019) (21)
- Self-association and ligand-induced conformational changes of iron regulatory proteins 1 and 2. (2005) (21)
- Measurements of iron status and survival in African iron overload. (1999) (21)
- Heme biosynthesis depends on previously unrecognized acquisition of iron-sulfur cofactors in human amino-levulinic acid dehydratase (2020) (20)
- A high-capacity RNA affinity column for the purification of human IRP1 and IRP2 overexpressed in Pichia pastoris. (2003) (19)
- Mechanisms of cellular iron sensing, regulation of erythropoiesis and mitochondrial iron utilization. (2021) (18)
- Targeting HIF2α Translation with Tempol in VHL-Deficient Clear Cell Renal Cell Carcinoma (2012) (18)
- Translational repression of HIF2&agr; expression in mice with Chuvash polycythemia reverses polycythemia (2018) (18)
- The molecular basis of iron metabolism. (1996) (15)
- A traditional beverage prevents iron deficiency in African women of child bearing age (1999) (14)
- The Promoter Region of the Human Transferrin Receptor Gene (1988) (14)
- Reply to “Iron homeostasis in the brain: complete iron regulatory protein 2 deficiency without symptomatic neurodegeneration in the mouse” (2006) (14)
- Orchestrated regulation of iron trafficking proteins in the kidney during iron overload facilitates systemic iron retention (2018) (13)
- Infused wild-type macrophages reside and self-renew in the liver to rescue the hemolysis and anemia of Hmox1-deficient mice. (2018) (13)
- Therapeutic inhibition of HIF2α reverses polycythemia and pulmonary hypertension in murine models of two human diseases. (2020) (13)
- Hepatitis C virus in Zimbabwe. (1997) (12)
- How does hepcidin hinder ferroportin activity? (2018) (12)
- Assembly of the [4Fe-4S] cluster of NFU1 requires the coordinated donation of two [2Fe-2S] clusters from the scaffold proteins, ISCU2 and ISCA1. (2020) (12)
- Linking physiological functions of iron (2005) (11)
- How Oxidation of a Unique Iron-Sulfur Cluster in FBXL5 Regulates IRP2 Levels and Promotes Regulation of Iron Metabolism Proteins. (2020) (11)
- Methods for Studying Iron Regulatory Protein 1: An Important Protein in Human Iron Metabolism. (2018) (9)
- Elevated FGF 21 secretion , PGC-1 a and ketogenic enzyme expression are hallmarks of iron – sulfur cluster depletion in human skeletal muscle (2013) (9)
- Effect of ascorbic acid administration on serum concentration of transferrin receptors. (1998) (9)
- Serum ferritin concentrations in Africans with low dietary iron (2009) (9)
- Tangled up in red: intertwining of the heme and iron-sulfur cluster biogenesis pathways. (2009) (9)
- Use of antisense oligonucleotides to correct the splicing error in ISCU myopathy patient cell lines. (2016) (9)
- Iron and alcohol content of traditional beers in rural Zimbabwe. (1999) (8)
- Biochemical and biophysical methods for studying mitochondrial iron metabolism. (2014) (8)
- 21 Translational Control of Ferritin Synthesis (2000) (7)
- If the RNA Fits, Use It (2006) (6)
- Disease-Causing SDHAF 1 Mutations Impair Transfer of FeS Clusters to SDHB Graphical Abstract Highlights (2016) (6)
- Essential role of systemic iron mobilization and redistribution for adaptive thermogenesis through HIF2-α/hepcidin axis (2021) (6)
- 13. Sensing the cellular Fe-S cluster demand: a structural, functional, and phylogenetic overview of Escherichia coli IscR (2014) (5)
- 11. A retrospective on the discovery of [Fe-S] cluster biosynthetic machineries in Azotobacter vinelandii (2014) (3)
- 6. The utility of Mössbauer spectroscopy in eukaryotic cell biology and animal physiology (2017) (3)
- A template-propagation method for segmentation of filamentous structures in electron tomograms (2004) (3)
- 15 DNA signaling by iron-sulfur cluster proteins (2017) (3)
- Ferritin is secreted via two distinct non-classical vesicular pathways Ferritin Trafficking and Secretion (2017) (3)
- Tissue Specificity of a Human Mitochondrial Disease DIFFERENTIATION-ENHANCED MIS-SPLICING OF THE Fe-S SCAFFOLD GENE ISCU RENDERS PATIENT CELLS MORE SENSITIVE TO OXIDATIVE STRESS IN ISCU MYOPATHY (2012) (3)
- Erratum: Iron overload in Africans and African-Americans and a common mutation in the SCL40A1 (ferroportin 1) gene (Blood Cells, Molecules, and Diseases (2003) 31 (299-304) DOI: 10.1016/S1079-9796(03)00164-5) (2004) (3)
- Mammalian iron sulfur cluster biogenesis and human diseases (2022) (3)
- Mammalian iron sulfur cluster biogenesis: From assembly to delivery to recipient proteins with a focus on novel targets of the chaperone and co‐chaperone proteins (2022) (2)
- Biochemistry. If the RNA fits, use it. (2006) (2)
- 4. Bioinorganic spectroscopy of iron sulfur proteins— an overview (2017) (2)
- Aconitase, the janus-faced protein: Tricarboxylate (DE)hydratase and iron regulating protein. (1993) (2)
- The Central Role of the Liver in Iron Storage and Regulation of Systemic Iron Homeostasis (2020) (2)
- 17 Origin and evolution of Fe-S proteins and enzymes (2017) (2)
- Iron Homeostasis in the CNS: An Overview of the Pathological Consequences of Iron Metabolism Disruption (2022) (2)
- 3. From the quantum chemistry of iron-sulfur clusters to redox energetics and reaction pathways in metalloenzymes (2017) (1)
- 10. Molybdenum-containing iron-sulfur enzymes (2014) (1)
- 8. The iron-molybdenum cofactor of nitrogenase (2017) (1)
- 14. Fe-S assembly in Gram-positive bacteria (2014) (1)
- Hereditary hemochromatosis—sometimes having a real complex can be a good thing (1998) (1)
- Dependence of heme biosynthesis on iron-sulfur cluster biogenesis: human ALAD is an unrecognized iron-sulfur protein (2020) (1)
- Regulation of Iron Metabolism in Mammalian Cells (2012) (1)
- 12. A stress-responsive Fe-S cluster biogenesis system in bacteria – the suf operon of Gammaproteobacteria (2014) (1)
- Hyperactivation of mTOR and AKT in a cardiac hypertrophy animal model of Friedreich ataxia (2022) (1)
- Iron and Isocitrate Calibrate Erythropoietin Responsiveness of Erythroid Progenitors Via Aconitase Tuning of Protein Kinase C Activity. (2009) (1)
- Iron sulfur proteins : a historical perspective (2014) (1)
- Dispensable iron-sulfur clusters: the interconversion of aconitase with the RNA-binding protein, IRE-BP (1994) (1)
- MetalloregulationBased in part on the article Metalloregulation by Robert P. Hausinger which appeared in the Encyclopedia of Inorganic Chemistry, First Edition. (2006) (1)
- Reply: IREB2-associated neurodegeneration. (2019) (1)
- 2. Chemistry of iron-sulfur clusters (2014) (1)
- RNA Structure and Function in Cellular Iron Homeostasis (1998) (1)
- 9. Biotin synthase: a role for iron-sulfur clusters in the radical-mediated generation of carbon-sulfur bonds (2017) (1)
- 2 The ISC system and the different facets of Fe-S biology in bacteria (2017) (1)
- Heme, whence come thy carbon building blocks? (2018) (1)
- 17. Biogenesis of Fe-S proteins in mammals (2014) (0)
- Iron-Responsive Elements (IRE) (2002) (0)
- The state of the iron-sulfur cluster of the iron-responsive element binding protein determines whether the protein will function as an RNA regulatory protein or as a cytosolic enzyme (1993) (0)
- Disruption of cellular iron homeostasis by IREB2 missense variants causes severe neurodevelopmental delay, dystonia and seizures. (2022) (0)
- Insertion mutants in Drosophila melanogaster Hsc20 halt larval growth and lead to reduced iron–sulfur cluster enzyme activities and impaired iron homeostasis (2013) (0)
- 9 Delivery of iron-sulfur clusters to recipient proteins: the role of chaperone and cochaperone proteins (2017) (0)
- Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression (2018) (0)
- Abstract B08: Metabolic adaption in inflammatory macrophages through the modulation of Fe-S cluster biogenesis factors (2016) (0)
- 16 Iron-sulfur cluster assembly in plants (2017) (0)
- Iron stores as reflected in serum ferritin concentrations en Africans with low dietary iron (2000) (0)
- Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase (2020) (0)
- Multiple Causes of Iron Overload In Tissues, Cells and Subcellular Compartments (2010) (0)
- The Regulation and Dynamics of the Transferrin Receptor (1986) (0)
- Cofactors and Coenzymes | Iron-Sulfur Clusters: Biogenesis, Roles and their Identification in the Cellular Proteins (2020) (0)
- The indispensable role of mammalian iron sulfur proteins in function and regulation of multiple diverse metabolic pathways (2019) (0)
- Abstract PO-147: Kidney iron overload in African American renal cancer patients with the ferroportin Q248H mutation (2020) (0)
- 16. The role of Fe-S clusters in regulation of yeast iron homeostasis (2014) (0)
- Post-Transcriptional Regulation of Iron Metabolism (2002) (0)
- Running title : iron-limited erythropoiesis in mice with IRP 2 deletion (2005) (0)
- Title: Biogenesis and Functions of Mammalian Iron-Sulfur Proteins in the Regulation of Iron Homeostasis and Pivotal Metabolic Pathways Running Title: Mammalian Fe-S proteins: biogenesis and functions (2017) (0)
- 5. Quantitative interpretation of EPR spectroscopy with applications for iron-sulfur proteins (2017) (0)
- LETTER TO THE EDITOR Reply: IREB2 -associated neurodegeneration (2019) (0)
- Ferroportin in Erythrocytes: Importance for Iron Homeostasis and its Role in Infection (2019) (0)
- FGF-21 secretion and ketogenic enzyme expression are hallmarks of chronic energy deficiency in human skeletal muscles depleted of iron sulfur clusters (2013) (0)
- Nitric Oxide Mediates Direct Restriction of Pyruvate Dehydrogenase Complex via Generation of Nitroxyl During Macrophage Polarization (2021) (0)
- 7. The interstitial carbide of the nitrogenase M-cluster: insertion pathway and possible function (2017) (0)
- Nucleic Acids-Research Detetional analysis of the promoter region of the human tronsferrin receptor gene (2005) (0)
- Genetic studies in Drosophila emphasize the functional importance of subcellular compartment boundaries for oxidative stress metabolism (2003) (0)
- Regulation of iron metabolism in eukaryotic cells. (1994) (0)
- Commentary 2: Iron Metabolism and Mitochondrial Abnormalities in Friedreich Ataxia (2002) (0)
- 10 Iron-sulfur proteins and human diseases (2017) (0)
- 12 Connecting the biosynthesis of the molybdenum cofactor, Fe-S clusters, and tRNA thiolation in humans (2017) (0)
- 9 Delivery of iron-sulfur clusters to recipient proteins: the role of chaperone and cochaperone proteins (2017) (0)
- Iron stores, HTV and pulmonary tuberculosis en southern Africa (2000) (0)
- Rural Community in Zimbabwe Traditional Beer Consumption and the Iron Status of Spouse Pairs From a (2011) (0)
- Effect of Ascorbic Acid Administration on Serum Concentration of Transferrin Receptors, Hlosukwazi (1998) (0)
- Aberrant iron homeostasis, oxidative fiber enrichment, and activation of ketogenesis in muscle tissue of ISCU Myopathy patients (2012) (0)
- 13 Iron-sulphur proteins and genome stability (2014) (0)
- 14 Eukaryotic iron-sulfur protein biogenesis and its role in maintaining genomic integrity (2017) (0)
- RED CELLS , IRON , AND ERYTHROPOIESIS Wild-type macrophages reverse disease in heme oxygenase 1-de fi cient mice (2014) (0)
- TEMPOL inhibits SARS-CoV-2 replication and development of lung disease in the Syrian hamster model (2022) (0)
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