Tracey Rouault
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American rheumatologist and physician-scientist
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Tracey Rouault's Degrees
- Doctorate Medicine Johns Hopkins University
- PhD Immunology Johns Hopkins University
Why Is Tracey Rouault Influential?
(Suggest an Edit or Addition)According to Wikipedia, Tracey Ann Rouault is an American rheumatologist and physician-scientist who researches mammalian iron-sulfur proteins. Rouault is a senior investigator at the Eunice Kennedy Shriver National Institute of Child Health and Human Development and she heads the section on human iron metabolism.
Tracey Rouault's Published Works
Published Works
- Regulating the fate of mRNA: The control of cellular iron metabolism (1993) (1175)
- The role of iron regulatory proteins in mammalian iron homeostasis and disease (2006) (904)
- A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression. (2005) (620)
- Iron-responsive elements: regulatory RNA sequences that control mRNA levels and translation. (1988) (604)
- Identification of the iron-responsive element for the translational regulation of human ferritin mRNA. (1987) (467)
- Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice (2001) (461)
- Iron–sulphur cluster biogenesis and mitochondrial iron homeostasis (2005) (383)
- Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis (2004) (375)
- Iron metabolism in the CNS: implications for neurodegenerative diseases (2013) (366)
- Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway. (2010) (360)
- Sedimentation equilibrium analysis of protein interactions with global implicit mass conservation constraints and systematic noise decomposition. (2004) (351)
- Hereditary hemochromatosis. (1993) (333)
- Iron-sulfur cluster biogenesis and human disease. (2008) (332)
- Oxidation-reduction and the molecular mechanism of a regulatory RNA-protein interaction. (1989) (321)
- Iron‐dependent regulation of the divalent metal ion transporter (2001) (305)
- Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: implications for degradation of oxidized proteins. (1998) (295)
- Cellular regulation of the iron-responsive element binding protein: disassembly of the cubane iron-sulfur cluster results in high-affinity RNA binding. (1992) (292)
- Biogenesis of iron-sulfur clusters in mammalian cells: new insights and relevance to human disease (2012) (292)
- Binding of a cytosolic protein to the iron-responsive element of human ferritin messenger RNA. (1988) (285)
- Brain iron metabolism. (2006) (275)
- Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis. (2006) (266)
- A ferroportin transcript that lacks an iron-responsive element enables duodenal and erythroid precursor cells to evade translational repression. (2009) (251)
- Structural relationship between an iron-regulated RNA-binding protein (IRE-BP) and aconitase: Functional implications (1991) (249)
- Regulation of iron metabolism in eukaryotes. (1997) (246)
- Iron on the brain (2001) (243)
- Mutations in iron-sulfur cluster scaffold genes NFU1 and BOLA3 cause a fatal deficiency of multiple respiratory chain and 2-oxoacid dehydrogenase enzymes. (2011) (242)
- Reciprocal control of RNA-binding and aconitase activity in the regulation of the iron-responsive element binding protein: role of the iron-sulfur cluster. (1992) (241)
- Mammalian Tissue Oxygen Levels Modulate Iron-Regulatory Protein Activities in Vivo (2004) (235)
- Iron-sulfur clusters as biosensors of oxidants and iron. (1996) (230)
- Human Iron−Sulfur Cluster Assembly, Cellular Iron Homeostasis, and Disease† (2010) (228)
- Dysfunction of the heme recycling system in heme oxygenase 1-deficient mice: effects on macrophage viability and tissue iron distribution. (2010) (222)
- Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2. (2005) (218)
- Molecular characterization of a second iron-responsive element binding protein, iron regulatory protein 2. Structure, function, and post-translational regulation. (1994) (217)
- Glutaredoxin 5 deficiency causes sideroblastic anemia by specifically impairing heme biosynthesis and depleting cytosolic iron in human erythroblasts. (2010) (216)
- Iron Accumulation in Deep Cortical Layers Accounts for MRI Signal Abnormalities in ALS: Correlating 7 Tesla MRI and Pathology (2012) (213)
- Distinct iron–sulfur cluster assembly complexes exist in the cytosol and mitochondria of human cells (2000) (201)
- A cis-acting element is necessary and sufficient for translational regulation of human ferritin expression in response to iron. (1987) (200)
- Requirements for iron‐regulated degradation of the RNA binding protein, iron regulatory protein 2. (1995) (198)
- Expression of the iron transporter ferroportin in synaptic vesicles and the blood–brain barrier (2004) (197)
- Splice mutation in the iron-sulfur cluster scaffold protein ISCU causes myopathy with exercise intolerance. (2008) (195)
- A regulated RNA binding protein also possesses aconitase activity. (1991) (193)
- Subcellular compartmentalization of human Nfu, an iron–sulfur cluster scaffold protein, and its ability to assemble a [4Fe–4S] cluster (2003) (191)
- Association of pulmonary tuberculosis with increased dietary iron. (2001) (191)
- Iron overload in Africans and African-Americans and a common mutation in the SCL40A1 (ferroportin 1) gene. (2003) (190)
- The glycolytic shift in fumarate-hydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels. (2011) (186)
- Mitochondrial iron chelation ameliorates cigarette-smoke induced bronchitis and emphysema in mice (2015) (177)
- The physiological functions of iron regulatory proteins in iron homeostasis - an update (2014) (176)
- Identification of the ubiquitin–protein ligase that recognizes oxidized IRP2 (2003) (175)
- Structure and dynamics of the iron responsive element RNA: implications for binding of the RNA by iron regulatory binding proteins. (1997) (175)
- Targeting of a human iron-sulfur cluster assembly enzyme, nifs, to different subcellular compartments is regulated through alternative AUG utilization. (1998) (173)
- Dietary iron overload as a risk factor for hepatocellular carcinoma in black africans (1998) (171)
- Iron-sulfur cluster biogenesis in mammalian cells: New insights into the molecular mechanisms of cluster delivery. (2015) (170)
- Cloning of the cDNA encoding an RNA regulatory protein--the human iron-responsive element-binding protein. (1990) (166)
- Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase (2020) (166)
- Molecular Pathways: Fumarate Hydratase-Deficient Kidney Cancer—Targeting the Warburg Effect in Cancer (2013) (165)
- Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression (2018) (164)
- Mammalian iron–sulphur proteins: novel insights into biogenesis and function (2014) (155)
- Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2α. (2013) (151)
- Human ISD11 is essential for both iron-sulfur cluster assembly and maintenance of normal cellular iron homeostasis. (2009) (139)
- Iron-dependent regulation of frataxin expression: implications for treatment of Friedreich ataxia (2008) (136)
- Regulation of interaction of the iron-responsive element binding protein with iron-responsive RNA elements (1989) (134)
- Differences in the RNA binding sites of iron regulatory proteins and potential target diversity. (1996) (134)
- Identification of a Conserved and Functional Iron-responsive Element in the 5′-Untranslated Region of Mammalian Mitochondrial Aconitase* (1996) (132)
- Both human ferredoxins 1 and 2 and ferredoxin reductase are important for iron-sulfur cluster biogenesis. (2012) (132)
- Metabolic regulation of citrate and iron by aconitases: role of iron–sulfur cluster biogenesis (2007) (131)
- The bifunctional iron-responsive element binding protein/cytosolic aconitase: the role of active-site residues in ligand binding and regulation. (1994) (128)
- Transcriptional regulation by iron of the gene for the transferrin receptor (1986) (123)
- Cochaperone binding to LYR motifs confers specificity of iron sulfur cluster delivery. (2014) (121)
- Brain iron homeostasis, the choroid plexus, and localization of iron transport proteins (2009) (119)
- Complete loss of iron regulatory proteins 1 and 2 prevents viability of murine zygotes beyond the blastocyst stage of embryonic development. (2006) (113)
- Clinical Severity and Thermodynamic Effects of Iron-responsive Element Mutations in Hereditary Hyperferritinemia-Cataract Syndrome* (1999) (113)
- Role of hepcidin in murine brain iron metabolism (2009) (113)
- The iron-responsive element binding protein: a method for the affinity purification of a regulatory RNA-binding protein. (1989) (112)
- Ferritin is secreted via 2 distinct nonclassical vesicular pathways. (2018) (111)
- Homeostatic Mechanisms for Iron Storage Revealed by Genetic Manipulations and Live Imaging of Drosophila Ferritin (2007) (109)
- Biogenesis and functions of mammalian iron-sulfur proteins in the regulation of iron homeostasis and pivotal metabolic pathways (2017) (107)
- The iron-responsive element-binding protein: localization of the RNA-binding site to the aconitase active-site cleft. (1994) (105)
- Characterization of mitochondrial ferritin in Drosophila. (2006) (105)
- A model for the structure and functions of iron-responsive elements. (1988) (102)
- A double life: cytosolic aconitase as a regulatory RNA binding protein. (1993) (101)
- Compartment-specific Protection of Iron-Sulfur Proteins by Superoxide Dismutase* (2003) (100)
- Posttranslational stability of the heme biosynthetic enzyme ferrochelatase is dependent on iron availability and intact iron-sulfur cluster assembly machinery. (2010) (94)
- Iron chaperones PCBP1 and PCBP2 mediate the metallation of the dinuclear iron enzyme deoxyhypusine hydroxylase (2014) (93)
- Mutations in LYRM4, encoding iron-sulfur cluster biogenesis factor ISD11, cause deficiency of multiple respiratory chain complexes. (2013) (93)
- Serum transferrin receptors are decreased in the presence of iron overload. (1998) (91)
- Systemic iron metabolism: a review and implications for brain iron metabolism. (2001) (91)
- Renal iron metabolism: transferrin iron delivery and the role of iron regulatory proteins. (2007) (91)
- Evidence of genetic transmission in African iron overload. (1998) (90)
- Hepcidin regulates ferroportin expression and intracellular iron homeostasis of erythroblasts. (2011) (88)
- Metabolic Reprogramming for Producing Energy and Reducing Power in Fumarate Hydratase Null Cells from Hereditary Leiomyomatosis Renal Cell Carcinoma (2013) (86)
- Modification of a free Fe-S cluster cysteine residue in the active iron-responsive element-binding protein prevents RNA binding. (1993) (86)
- Targeting ABL1-mediated oxidative stress adaptation in fumarate hydratase-deficient cancer. (2014) (85)
- Roles of the Mammalian Cytosolic Cysteine Desulfurase, ISCS, and Scaffold Protein, ISCU, in Iron-Sulfur Cluster Assembly* (2006) (83)
- Characterization of the human HSC20, an unusual DnaJ type III protein, involved in iron-sulfur cluster biogenesis. (2010) (83)
- Neuroprotective mechanism of mitochondrial ferritin on 6-hydroxydopamine-induced dopaminergic cell damage: implication for neuroprotection in Parkinson's disease. (2010) (82)
- Erythrocytic ferroportin reduces intracellular iron accumulation, hemolysis, and malaria risk (2018) (81)
- Tempol-mediated activation of latent iron regulatory protein activity prevents symptoms of neurodegenerative disease in IRP2 knockout mice (2008) (75)
- Hemin, chelatable iron, and the regulation of transferrin receptor biosynthesis. (1985) (75)
- The iron-responsive element binding protein: a target for synaptic actions of nitric oxide. (1994) (73)
- Disease-Causing SDHAF1 Mutations Impair Transfer of Fe-S Clusters to SDHB. (2016) (72)
- The iron-responsive element is the single element responsible for iron-dependent translational regulation of ferritin biosynthesis. Evidence for function as the binding site for a translational repressor. (1988) (69)
- Advancements in the pathophysiology of Friedreich's Ataxia and new prospects for treatments. (2007) (69)
- Iron control of erythroid development by a novel aconitase-associated regulatory pathway. (2010) (66)
- Pathogenic Bacteria Prefer Heme (2004) (65)
- Iron regulates the activity of the iron-responsive element binding protein without changing its rate of synthesis or degradation. (1992) (62)
- Cell‐cycle arrest and inhibition of G1 cyclin translation by iron in AFT1‐1up yeast (1998) (61)
- SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery. (2015) (61)
- Acute loss of iron–sulfur clusters results in metabolic reprogramming and generation of lipid droplets in mammalian cells (2018) (61)
- Elevated FGF21 secretion, PGC-1α and ketogenic enzyme expression are hallmarks of iron-sulfur cluster depletion in human skeletal muscle. (2014) (60)
- MRI detection of ferritin iron overload and associated neuronal pathology in iron regulatory protein-2 knockout mice (2003) (59)
- Outlining the Complex Pathway of Mammalian Fe-S Cluster Biogenesis. (2020) (57)
- A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III. (2017) (55)
- Electron tomography of degenerating neurons in mice with abnormal regulation of iron metabolism. (2005) (53)
- Iron Insufficiency Compromises Motor Neurons and Their Mitochondrial Function in Irp2-Null Mice (2011) (53)
- Of Two Cytosolic Aconitases Expressed in Drosophila, Only One Functions as an Iron-regulatory Protein* (2006) (52)
- Iron-sulfur proteins hiding in plain sight. (2015) (52)
- Specific binding of host cell proteins to the 3'-terminal stem-loop structure of rubella virus negative-strand RNA (1991) (51)
- Ferroportin deficiency in erythroid cells causes serum iron deficiency and promotes hemolysis due to oxidative stress. (2018) (51)
- Post-transcriptional regulation of human iron metabolism by iron regulatory proteins. (2002) (51)
- The role of endogenous heme synthesis and degradation domain cysteines in cellular iron-dependent degradation of IRP2. (2003) (50)
- Regulation of intracellular iron metabolism in human erythroid precursors by internalized extracellular ferritin. (1999) (50)
- African iron overload and hepatocellular carcinoma (HA‐7–0–080) (1998) (49)
- Mitochondrial iron overload: causes and consequences. (2016) (48)
- Mitochondrial DNA alterations underlie an irreversible shift to aerobic glycolysis in fumarate hydratase–deficient renal cancer (2021) (48)
- Iron overload in urban Africans in the 1990s (1999) (48)
- Specific high-affinity binding of host cell proteins to the 3' region of rubella virus RNA. (1990) (47)
- Influence of altered transcription on the translational control of human ferritin expression. (1987) (47)
- Wild-type macrophages reverse disease in heme oxygenase 1-deficient mice. (2014) (46)
- Novel Frataxin Isoforms May Contribute to the Pathological Mechanism of Friedreich Ataxia (2012) (45)
- The indispensable role of mammalian iron sulfur proteins in function and regulation of multiple diverse metabolic pathways (2019) (44)
- Iron misregulation and neurodegenerative disease in mouse models that lack iron regulatory proteins (2015) (43)
- Fe-S cofactors in the SARS-CoV-2 RNA-dependent RNA polymerase are potential antiviral targets (2021) (43)
- Traditional beer consumption and the iron status of spouse pairs from a rural community in Zimbabwe. (1997) (42)
- Hepatic iron overload in alcoholic liver disease: why does it occur and what is its role in pathogenesis? (2003) (42)
- An IRP-like protein from Plasmodium falciparum binds to a mammalian iron-responsive element. (2001) (42)
- Erythropoiesis and Iron Sulfur Cluster Biogenesis (2010) (41)
- Non‐transferrin‐bound iron and hepatic dysfunction in African dietary iron overload (1999) (41)
- Iron Regulatory Protein 2 as Iron Sensor (2003) (40)
- Neurochemical investigations of dopamine neuronal systems in iron-regulatory protein 2 (IRP-2) knockout mice. (2005) (39)
- Mammalian iron-sulfur cluster biogenesis: Recent insights into the roles of frataxin, acyl carrier protein and ATPase-mediated transfer to recipient proteins. (2020) (38)
- Expression of Human Frataxin Is Regulated by Transcription Factors SRF and TFAP2 (2010) (37)
- Post-transcriptional regulation of genes of iron metabolism in mammalian cells (1996) (37)
- An iron regulatory-like protein expressed in Plasmodium falciparum displays aconitase activity. (2005) (36)
- Overexpression of iron-responsive element-binding protein and its analytical characterization as the RNA-binding form, devoid of an iron-sulfur cluster. (1994) (35)
- An iron-sulfur cluster plays a novel regulatory role in the iron-responsive element binding protein (1992) (35)
- Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis (2019) (35)
- The inhibition of the iron responsive element RNA-protein interaction by heme does not mimic in vivo iron regulation. (1990) (34)
- Expression of a recombinant IRP-like Plasmodium falciparum protein that specifically binds putative plasmodial IREs. (2003) (34)
- Identification of a Heme-sensing Domain in Iron Regulatory Protein 2* (2004) (34)
- Tissue Specificity of a Human Mitochondrial Disease (2012) (33)
- Identification and characterization of host factor interactions with cis-acting elements of rubella virus RNA. (1994) (32)
- Absence of iron-responsive element-binding protein 2 causes a novel neurodegenerative syndrome. (2019) (32)
- Potential role of iron in repair of inflammatory demyelinating lesions. (2019) (32)
- Numerous Proteins in Mammalian Cells Are Prone to Iron-Dependent Oxidation and Proteasomal Degradation (2002) (31)
- Deletional analysis of the promoter region of the human transferrin receptor gene. (1988) (31)
- Differences in the terminal steps of complement lysis of normal and paroxysmal nocturnal hemoglobinuria red cells. (1978) (31)
- Cytosolic HSC20 integrates de novo iron–sulfur cluster biogenesis with the CIAO1-mediated transfer to recipients (2018) (30)
- SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery. (2016) (30)
- 12 Translational Control of Ferritin (1996) (29)
- How Mammals Acquire and Distribute Iron Needed for Oxygen-Based Metabolism (2003) (29)
- Cell-cycle arrest and inhibition of G1 cyclin translation by iron in AFT1-1(up) yeast. (1998) (29)
- MCV as a guide to phlebotomy therapyfor hemochromatosis (2001) (29)
- The impact of oxidative stress on eukaryotic iron metabolism. (1996) (28)
- The Intestinal Heme Transporter Revealed (2005) (28)
- Iron-sulfur clusters in chemistry and biology (2014) (27)
- Mammalian Fe-S proteins: definition of a consensus motif recognized by the co-chaperone HSC20. (2016) (27)
- Sequence and expression of the murine iron-responsive element binding protein. (1991) (26)
- Ferritin overexpression in Drosophila glia leads to iron deposition in the optic lobes and late-onset behavioral defects (2011) (26)
- TLR-activated repression of Fe-S cluster biogenesis drives a metabolic shift and alters histone and tubulin acetylation. (2018) (26)
- An Ancient Gauge for Iron (2009) (24)
- Manganese targets m‐aconitase and activates iron regulatory protein 2 in AF5 GABAergic cells (2007) (24)
- Behavioral decline and premature lethality upon pan-neuronal ferritin overexpression in Drosophila infected with a virulent form of Wolbachia (2014) (23)
- Insertion mutants in Drosophila melanogaster Hsc20 halt larval growth and lead to reduced iron–sulfur cluster enzyme activities and impaired iron homeostasis (2013) (21)
- Glia maturation factor-γ regulates murine macrophage iron metabolism and M2 polarization through mitochondrial ROS. (2019) (21)
- Self-association and ligand-induced conformational changes of iron regulatory proteins 1 and 2. (2005) (21)
- Measurements of iron status and survival in African iron overload. (1999) (21)
- Heme biosynthesis depends on previously unrecognized acquisition of iron-sulfur cofactors in human amino-levulinic acid dehydratase (2020) (20)
- A high-capacity RNA affinity column for the purification of human IRP1 and IRP2 overexpressed in Pichia pastoris. (2003) (19)
- Mechanisms of cellular iron sensing, regulation of erythropoiesis and mitochondrial iron utilization. (2021) (18)
- Targeting HIF2α Translation with Tempol in VHL-Deficient Clear Cell Renal Cell Carcinoma (2012) (18)
- Translational repression of HIF2&agr; expression in mice with Chuvash polycythemia reverses polycythemia (2018) (18)
- The molecular basis of iron metabolism. (1996) (15)
- A traditional beverage prevents iron deficiency in African women of child bearing age (1999) (14)
- The Promoter Region of the Human Transferrin Receptor Gene (1988) (14)
- Reply to “Iron homeostasis in the brain: complete iron regulatory protein 2 deficiency without symptomatic neurodegeneration in the mouse” (2006) (14)
- Orchestrated regulation of iron trafficking proteins in the kidney during iron overload facilitates systemic iron retention (2018) (13)
- Infused wild-type macrophages reside and self-renew in the liver to rescue the hemolysis and anemia of Hmox1-deficient mice. (2018) (13)
- Therapeutic inhibition of HIF2α reverses polycythemia and pulmonary hypertension in murine models of two human diseases. (2020) (13)
- Hepatitis C virus in Zimbabwe. (1997) (12)
- How does hepcidin hinder ferroportin activity? (2018) (12)
- Assembly of the [4Fe-4S] cluster of NFU1 requires the coordinated donation of two [2Fe-2S] clusters from the scaffold proteins, ISCU2 and ISCA1. (2020) (12)
- Linking physiological functions of iron (2005) (11)
- How Oxidation of a Unique Iron-Sulfur Cluster in FBXL5 Regulates IRP2 Levels and Promotes Regulation of Iron Metabolism Proteins. (2020) (11)
- Methods for Studying Iron Regulatory Protein 1: An Important Protein in Human Iron Metabolism. (2018) (9)
- Elevated FGF 21 secretion , PGC-1 a and ketogenic enzyme expression are hallmarks of iron – sulfur cluster depletion in human skeletal muscle (2013) (9)
- Effect of ascorbic acid administration on serum concentration of transferrin receptors. (1998) (9)
- Serum ferritin concentrations in Africans with low dietary iron (2009) (9)
- Tangled up in red: intertwining of the heme and iron-sulfur cluster biogenesis pathways. (2009) (9)
- Use of antisense oligonucleotides to correct the splicing error in ISCU myopathy patient cell lines. (2016) (9)
- Iron and alcohol content of traditional beers in rural Zimbabwe. (1999) (8)
- Biochemical and biophysical methods for studying mitochondrial iron metabolism. (2014) (8)
- 21 Translational Control of Ferritin Synthesis (2000) (7)
- If the RNA Fits, Use It (2006) (6)
- Disease-Causing SDHAF 1 Mutations Impair Transfer of FeS Clusters to SDHB Graphical Abstract Highlights (2016) (6)
- Essential role of systemic iron mobilization and redistribution for adaptive thermogenesis through HIF2-α/hepcidin axis (2021) (6)
- 13. Sensing the cellular Fe-S cluster demand: a structural, functional, and phylogenetic overview of Escherichia coli IscR (2014) (5)
- 11. A retrospective on the discovery of [Fe-S] cluster biosynthetic machineries in Azotobacter vinelandii (2014) (3)
- 6. The utility of Mössbauer spectroscopy in eukaryotic cell biology and animal physiology (2017) (3)
- A template-propagation method for segmentation of filamentous structures in electron tomograms (2004) (3)
- 15 DNA signaling by iron-sulfur cluster proteins (2017) (3)
- Ferritin is secreted via two distinct non-classical vesicular pathways Ferritin Trafficking and Secretion (2017) (3)
- Tissue Specificity of a Human Mitochondrial Disease DIFFERENTIATION-ENHANCED MIS-SPLICING OF THE Fe-S SCAFFOLD GENE ISCU RENDERS PATIENT CELLS MORE SENSITIVE TO OXIDATIVE STRESS IN ISCU MYOPATHY (2012) (3)
- Erratum: Iron overload in Africans and African-Americans and a common mutation in the SCL40A1 (ferroportin 1) gene (Blood Cells, Molecules, and Diseases (2003) 31 (299-304) DOI: 10.1016/S1079-9796(03)00164-5) (2004) (3)
- Mammalian iron sulfur cluster biogenesis and human diseases (2022) (3)
- Mammalian iron sulfur cluster biogenesis: From assembly to delivery to recipient proteins with a focus on novel targets of the chaperone and co‐chaperone proteins (2022) (2)
- Biochemistry. If the RNA fits, use it. (2006) (2)
- 4. Bioinorganic spectroscopy of iron sulfur proteins— an overview (2017) (2)
- Aconitase, the janus-faced protein: Tricarboxylate (DE)hydratase and iron regulating protein. (1993) (2)
- The Central Role of the Liver in Iron Storage and Regulation of Systemic Iron Homeostasis (2020) (2)
- 17 Origin and evolution of Fe-S proteins and enzymes (2017) (2)
- Iron Homeostasis in the CNS: An Overview of the Pathological Consequences of Iron Metabolism Disruption (2022) (2)
- 3. From the quantum chemistry of iron-sulfur clusters to redox energetics and reaction pathways in metalloenzymes (2017) (1)
- 10. Molybdenum-containing iron-sulfur enzymes (2014) (1)
- 8. The iron-molybdenum cofactor of nitrogenase (2017) (1)
- 14. Fe-S assembly in Gram-positive bacteria (2014) (1)
- Hereditary hemochromatosis—sometimes having a real complex can be a good thing (1998) (1)
- Dependence of heme biosynthesis on iron-sulfur cluster biogenesis: human ALAD is an unrecognized iron-sulfur protein (2020) (1)
- Regulation of Iron Metabolism in Mammalian Cells (2012) (1)
- 12. A stress-responsive Fe-S cluster biogenesis system in bacteria – the suf operon of Gammaproteobacteria (2014) (1)
- Hyperactivation of mTOR and AKT in a cardiac hypertrophy animal model of Friedreich ataxia (2022) (1)
- Iron and Isocitrate Calibrate Erythropoietin Responsiveness of Erythroid Progenitors Via Aconitase Tuning of Protein Kinase C Activity. (2009) (1)
- Iron sulfur proteins : a historical perspective (2014) (1)
- Dispensable iron-sulfur clusters: the interconversion of aconitase with the RNA-binding protein, IRE-BP (1994) (1)
- MetalloregulationBased in part on the article Metalloregulation by Robert P. Hausinger which appeared in the Encyclopedia of Inorganic Chemistry, First Edition. (2006) (1)
- Reply: IREB2-associated neurodegeneration. (2019) (1)
- 2. Chemistry of iron-sulfur clusters (2014) (1)
- RNA Structure and Function in Cellular Iron Homeostasis (1998) (1)
- 9. Biotin synthase: a role for iron-sulfur clusters in the radical-mediated generation of carbon-sulfur bonds (2017) (1)
- 2 The ISC system and the different facets of Fe-S biology in bacteria (2017) (1)
- Heme, whence come thy carbon building blocks? (2018) (1)
- 17. Biogenesis of Fe-S proteins in mammals (2014) (0)
- Iron-Responsive Elements (IRE) (2002) (0)
- The state of the iron-sulfur cluster of the iron-responsive element binding protein determines whether the protein will function as an RNA regulatory protein or as a cytosolic enzyme (1993) (0)
- Disruption of cellular iron homeostasis by IREB2 missense variants causes severe neurodevelopmental delay, dystonia and seizures. (2022) (0)
- Insertion mutants in Drosophila melanogaster Hsc20 halt larval growth and lead to reduced iron–sulfur cluster enzyme activities and impaired iron homeostasis (2013) (0)
- 9 Delivery of iron-sulfur clusters to recipient proteins: the role of chaperone and cochaperone proteins (2017) (0)
- Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression (2018) (0)
- Abstract B08: Metabolic adaption in inflammatory macrophages through the modulation of Fe-S cluster biogenesis factors (2016) (0)
- 16 Iron-sulfur cluster assembly in plants (2017) (0)
- Iron stores as reflected in serum ferritin concentrations en Africans with low dietary iron (2000) (0)
- Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase (2020) (0)
- Multiple Causes of Iron Overload In Tissues, Cells and Subcellular Compartments (2010) (0)
- The Regulation and Dynamics of the Transferrin Receptor (1986) (0)
- Cofactors and Coenzymes | Iron-Sulfur Clusters: Biogenesis, Roles and their Identification in the Cellular Proteins (2020) (0)
- The indispensable role of mammalian iron sulfur proteins in function and regulation of multiple diverse metabolic pathways (2019) (0)
- Abstract PO-147: Kidney iron overload in African American renal cancer patients with the ferroportin Q248H mutation (2020) (0)
- 16. The role of Fe-S clusters in regulation of yeast iron homeostasis (2014) (0)
- Post-Transcriptional Regulation of Iron Metabolism (2002) (0)
- Running title : iron-limited erythropoiesis in mice with IRP 2 deletion (2005) (0)
- Title: Biogenesis and Functions of Mammalian Iron-Sulfur Proteins in the Regulation of Iron Homeostasis and Pivotal Metabolic Pathways Running Title: Mammalian Fe-S proteins: biogenesis and functions (2017) (0)
- 5. Quantitative interpretation of EPR spectroscopy with applications for iron-sulfur proteins (2017) (0)
- LETTER TO THE EDITOR Reply: IREB2 -associated neurodegeneration (2019) (0)
- Ferroportin in Erythrocytes: Importance for Iron Homeostasis and its Role in Infection (2019) (0)
- FGF-21 secretion and ketogenic enzyme expression are hallmarks of chronic energy deficiency in human skeletal muscles depleted of iron sulfur clusters (2013) (0)
- Nitric Oxide Mediates Direct Restriction of Pyruvate Dehydrogenase Complex via Generation of Nitroxyl During Macrophage Polarization (2021) (0)
- 7. The interstitial carbide of the nitrogenase M-cluster: insertion pathway and possible function (2017) (0)
- Nucleic Acids-Research Detetional analysis of the promoter region of the human tronsferrin receptor gene (2005) (0)
- Genetic studies in Drosophila emphasize the functional importance of subcellular compartment boundaries for oxidative stress metabolism (2003) (0)
- Regulation of iron metabolism in eukaryotic cells. (1994) (0)
- Commentary 2: Iron Metabolism and Mitochondrial Abnormalities in Friedreich Ataxia (2002) (0)
- 10 Iron-sulfur proteins and human diseases (2017) (0)
- 12 Connecting the biosynthesis of the molybdenum cofactor, Fe-S clusters, and tRNA thiolation in humans (2017) (0)
- 9 Delivery of iron-sulfur clusters to recipient proteins: the role of chaperone and cochaperone proteins (2017) (0)
- Iron stores, HTV and pulmonary tuberculosis en southern Africa (2000) (0)
- Rural Community in Zimbabwe Traditional Beer Consumption and the Iron Status of Spouse Pairs From a (2011) (0)
- Effect of Ascorbic Acid Administration on Serum Concentration of Transferrin Receptors, Hlosukwazi (1998) (0)
- Aberrant iron homeostasis, oxidative fiber enrichment, and activation of ketogenesis in muscle tissue of ISCU Myopathy patients (2012) (0)
- 13 Iron-sulphur proteins and genome stability (2014) (0)
- 14 Eukaryotic iron-sulfur protein biogenesis and its role in maintaining genomic integrity (2017) (0)
- RED CELLS , IRON , AND ERYTHROPOIESIS Wild-type macrophages reverse disease in heme oxygenase 1-de fi cient mice (2014) (0)
- TEMPOL inhibits SARS-CoV-2 replication and development of lung disease in the Syrian hamster model (2022) (0)
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