Trevor Sharp

Q: What Schools Are Affiliated With Trevor Sharp

Trevor Sharp is affiliated with the following schools: University of California, Berkeley, University of Oxford, Stanford University

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Trevor Sharp

Computer Science

#5401

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#5709

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Machine Learning

#1421

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#1443

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Artificial Intelligence

#1655

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#1687

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#2553

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#2675

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Computer Science

Trevor Sharp's Degrees

PhD Computer Science Stanford University
Masters Artificial Intelligence University of California, Berkeley

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Trevor Sharp's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

A review of central 5-HT receptors and their function (1999) (3091)
In Vivo Measurement of Dopamine and Its Metabolites by Intracerebral Dialysis: Changes After d‐Amphetamine (1983) (613)
A direct comparison of amphetamine-induced behaviours and regional brain dopamine release in the rat using intracerebral dialysis (1987) (410)
Catechol-O-Methyltransferase Inhibition Improves Set-Shifting Performance and Elevates Stimulated Dopamine Release in the Rat Prefrontal Cortex (2004) (402)
In vivo measurement of extracellular dopamine and DOPAC in rat striatum after various dopamine-releasing drugs; implications for the origin of extracellular DOPAC. (1988) (398)
5‐HT1 agonists reduce 5‐hydroxytryptamine release in rat hippocampus in vivo as determined by brain microdialysis (1989) (346)
Interaction between a selective 5‐HT1A receptor antagonist and an SSRI in vivo: effects on 5‐HT cell firing and extracellular 5‐HT (1995) (335)
Induction of c-Fos expression in specific areas of the fear circuitry in rat forebrain by anxiogenic drugs (2003) (332)
An electrophysiological and neuroanatomical study of the medial prefrontal cortical projection to the midbrain raphe nuclei in the rat (1998) (313)
Differential involvement of serotonin and dopamine systems in cost-benefit decisions about delay or effort (2005) (297)
An In Vivo Study of Dopamine Release and Metabolism in Rat Brain Regions Using Intracerebral Dialysis (1986) (262)
Effect of neuroleptic drugs on striatal dopamine release and metabolism in the awake rat studied by intracerebral dialysis. (1984) (253)
In Vivo Measurement of Extracellular 5‐Hydroxytryptamine in Hippocampus of the Anaesthetized Rat Using Microdialysis: Changes in Relation to 5‐Hydroxytryptaminergic Neuronal Activity (1989) (241)
Role of the medial prefrontal cortex in 5‐HT1A receptor‐induced inhibition of 5‐HT neuronal activity in the rat (1999) (227)
A safe lithium mimetic for bipolar disorder (2012) (215)
Effect of the 5-HT1A receptor agonist 8-OH-DPAT on the release of 5-HT in dorsal and median raphe-innervated rat brain regions as measured by in vivo microdialysis. (1991) (215)
Inhibition of 5-HT neuron activity and induction of depressive-like behavior by high-frequency stimulation of the subthalamic nucleus (2007) (207)
Functional Mapping of Dorsal and Median Raphe 5‐Hydroxytryptamine Pathways in Forebrain of the Rat Using Microdialysis (1997) (202)
In vivo measurement of spontaneous release and metabolism of dopamine from intrastriatal nigral grafts using intracerebral dialysis (1986) (193)
Autoregulation of dopamine release and metabolism by intrastriatal nigral grafts as revealed by intracerebral dialysis (1987) (188)
Neurochemical and anatomical identification of fast- and slow-firing neurones in the rat dorsal raphe nucleus using juxtacellular labelling methods in vivo (2003) (182)
Important messages in the 'post': recent discoveries in 5-HT neurone feedback control. (2007) (177)
Evidence for a role of GABA interneurones in the cortical modulation of midbrain 5-hydroxytryptamine neurones (2001) (161)
Long‐term behavioural, molecular and morphological effects of neonatal NMDA receptor antagonism (2003) (160)
Effect of a tyrosine-free amino acid mixture on regional brain catecholamine synthesis and release (1999) (158)
Increased Expression of the 5-HT Transporter Confers a Low- Anxiety Phenotype Linked to Decreased 5-HT Transmission (2006) (155)
Pharmacological characterization of 8‐OH‐DPAT‐induced inhibition of rat hippocampal 5‐HT release in vivo as measured by microdialysis (1989) (146)
Effect of a selective 5‐HT reuptake inhibitor in combination with 5‐HT1A and 5‐HT1B receptor antagonists on extracellular 5‐HT in rat frontal cortex in vivo (1997) (144)
Neuroanatomical targets of anxiogenic drugs in the hindbrain as revealed by Fos immunocytochemistry (2000) (143)
Interaction of the novel antipsychotic aripiprazole with 5-HT1A and 5-HT2A receptors: functional receptor-binding and in vivo electrophysiological studies (2007) (137)
Further evaluation of the mechanism by which amphetamine reduces striatal dopamine metabolism: a brain dialysis study. (1986) (132)
Comparing the role of the anterior cingulate cortex and 6‐hydroxydopamine nucleus accumbens lesions on operant effort‐based decision making (2009) (130)
Biochemical evidence for the regulation of central noradrenergic activity by 5-HT1A and 5-HT2 receptors: Microdialysis studies in the awake and anaesthetized rat (1994) (129)
Electrophysiological evidence for convergence of inputs from the medial prefrontal cortex and lateral habenula on single neurons in the dorsal raphe nucleus (2003) (127)
Mixed agonist/antagonist properties of NAN-190 at 5-HT1A receptors: behavioural and in vivo brain microdialysis studies. (1990) (126)
S32006, a novel 5-HT2C receptor antagonist displaying broad-based antidepressant and anxiolytic properties in rodent models (2008) (125)
Antidopaminergic effects of dietary tyrosine depletion in healthy subjects and patients with manic illness (2001) (124)
Confounding effects of anesthesia on functional activation in rodent brain: a study of halothane and α-chloralose anesthesia (2005) (123)
Serotonin, Amygdala and Fear: Assembling the Puzzle (2016) (122)
In vivo evidence that 5‐HT2C receptors inhibit 5‐HT neuronal activity via a GABAergic mechanism (2006) (117)
Application of brain microdialysis to study the pharmacology of the 5-HT1A autoreceptor (1990) (115)
In vivo inhibition of neuronal activity in the rat ventromedial prefrontal cortex by midbrain-raphe nuclei: role of 5-HT1A receptors (2003) (114)
Effect of antidepressant drugs on dopamine D1 and D2 receptor expression and dopamine release in the nucleus accumbens of the rat (1998) (109)
Evidence for a repetitive (burst) firing pattern in a sub-population of 5-hydroxytryptamine neurons in the dorsal and median raphe nuclei of the rat (1995) (108)
Behavioural evidence for a functional interaction between central 5‐HT2 and 5‐HT1A receptors (1990) (108)
Further investigation of the in vivo pharmacological properties of the putative 5-HT1A antagonist, BMY 7378. (1990) (106)
Changes in monoamine metabolites measured by simultaneousin vivo differential pulse voltammetry and intracerebral dialysis (1984) (105)
Neurochemical and electrophysiological studies on the functional significance of burst firing in serotonergic neurons (2000) (105)
Neurochemical identification of stereotypic burst‐firing neurons in the rat dorsal raphe nucleus using juxtacellular labelling methods (2007) (98)
Electrical stimulation alleviates depressive-like behaviors of rats: investigation of brain targets and potential mechanisms (2015) (94)
Differential pulse voltammetry in vivo - evidence that uric acid contributes to the indole oxidation peak (1983) (93)
In vivo microdialysis evidence for central serotonin1A and serotonin1B autoreceptor blocking properties of the beta adrenoceptor antagonist (-)penbutolol. (1993) (93)
5-HT and depression: is the glass half-full? (2011) (93)
Antidepressant drug treatment induces Arc gene expression in the rat brain (2003) (86)
Release of endogenous 5-hydroxytryptamine in rat ventral hippocampus evoked by electrical stimulation of the dorsal raphe nucleus as detected by microdialysis: Sensitivity to tetrodotoxin, calcium and calcium antagonists (1990) (83)
Evidence that central 5‐HT2A and 5‐HT2B/C receptors regulate 5‐HT cell firing in the dorsal raphe nucleus of the anaesthetised rat (2003) (83)
Measurement of GABA in rat brain microdialysates using o-phthaldialdehyde-sulphite derivatization and high-performance liquid chromatography with electrochemical detection. (1994) (82)
Electrophysiological and neurochemical evidence that pindolol has agonist properties at the 5‐HT1A autoreceptor in vivo (1998) (82)
Evidence that 5‐HT2 receptor activation decreases noradrenaline release in rat hippocampus in vivo (1992) (80)
Effect of acute administration of L-tryptophan on the release of 5-HT in rat hippocampus in relation to serotoninergic neuronal activity: an in vivo microdialysis study. (1992) (80)
Control of Amygdala Circuits by 5-HT Neurons via 5-HT and Glutamate Cotransmission (2017) (79)
Effect of 5-hydroxy-l-tryptophan on the release of 5-HT in rat hypothalamus in vivo as measured by microdialysis (1992) (79)
β-blocker Binding to Human 5-HT1A Receptors in vivo and in vitro: Implications for Antidepressant Therapy (2000) (77)
Serotonin-dependent depression in Parkinson’s disease: A role for the subthalamic nucleus? (2011) (77)
Inhibition of median and dorsal raphe neurones following administration of the selective serotonin reuptake inhibitor paroxetine (1995) (75)
Effect of the putative lithium mimetic ebselen on brain myo-inositol, sleep and emotional processing in humans (2016) (75)
p-Chloroamphetamine releases both serotonin and dopamine into rat brain dialysates in vivo (1986) (75)
Effect of naloxone-precipitated morphine withdrawal on noradrenaline release in rat hippocampus in vivo. (1992) (74)
Does gene deletion of AMPA GluA1 phenocopy features of schizoaffective disorder? (2010) (74)
Inhibition of 5-HT cell firing in the DRN by non-selective 5-HT reuptake inhibitors: studies on the role of 5-HT1A autoreceptors and noradrenergic mechanisms (1997) (73)
Regulation of markers of synaptic function in mouse models of depression: chronic mild stress and decreased expression of VGLUT1 (2010) (72)
Deep brain stimulation of the nucleus accumbens shell increases impulsive behavior and tissue levels of dopamine and serotonin (2010) (72)
Effect of a selective 5-hydroxytryptamine reuptake inhibitor on brain extracellular noradrenaline: microdialysis studies using paroxetine. (2000) (72)
Evidence for increased expression of the vesicular glutamate transporter, VGLUT1, by a course of antidepressant treatment (2005) (71)
Widespread Distribution of Binding Sites for the Novel Ca2+-mobilizing Messenger, Nicotinic Acid Adenine Dinucleotide Phosphate, in the Brain* (2000) (70)
Studies on the role of 5-HT1A autoreceptors and α 1-adrenoceptors in the inhibition of 5-HT release—I. BMY7378 and prazosin (1995) (67)
Opposing alterations in anxiety and species-typical behaviours in serotonin transporter overexpressor and knockout mice (2011) (65)
Effects of the potential lithium-mimetic, ebselen, on impulsivity and emotional processing (2016) (63)
Olanzapine activates the rat locus coeruleus: in vivo electrophysiology and c-Fos immunoreactivity (2001) (63)
Release of cerebral 5-hydroxytryptamine evoked by electrical stimulation of the dorsal and median raphe nuclei: effect of a neurotoxic amphetamine (1995) (62)
Increase of 5-HT7 (serotonin-7) and 5-HT1A (serotonin-1A) receptor mRNA expression in rat hippocampus after adrenalectomy (1997) (62)
Investigation of the SSRI augmentation properties of 5-HT2 receptor antagonists using in vivo microdialysis (2006) (62)
HPLC-EC analysis of catechols and indoles in rat brain dialysates. (1987) (61)
Sexually Dimorphic Effects of Catechol-O-Methyltransferase (COMT) Inhibition on Dopamine Metabolism in Multiple Brain Regions (2013) (61)
Effects of (−)‐tertatolol, (−)‐penbutolol and (±)‐pindolol in combination with paroxetine on presynaptic 5‐HT function: an in vivo microdialysis and electrophysiological study (1999) (60)
Brain responses to chronic social defeat stress: Effects on regional oxidative metabolism as a function of a hedonic trait, and gene expression in susceptible and resilient rats (2011) (59)
Repeated ECS differentially affects rat brain 5-HT1A and 5-HT2A receptor expression (1995) (59)
Central 5-HT receptors and their function; present and future (2020) (58)
Comparison of the effects of a-methyl-p-tyrosine and a tyrosine-free amino acid load on extracellular noradrenaline in the rat hippocampus in vivo (1999) (58)
S32504, a Novel Naphtoxazine Agonist at Dopamine D3/D2 Receptors: III. Actions in Models of Potential Antidepressive and Anxiolytic Activity in Comparison with Ropinirole (2004) (54)
Influence of 5-HT1A receptors on central noradrenergic activity: microdialysis studies using (±)-MDL 73005EF and its enantiomers (1999) (53)
Activation of 5-HT6 receptors facilitates attentional set shifting (2009) (52)
Further pharmacological characterization of 5‐HT2C receptor agonist‐induced inhibition of 5‐HT neuronal activity in the dorsal raphe nucleus in vivo (2009) (52)
A role for midbrain raphe &ggr; aminobutyric acid neurons in 5-hydroxytryptamine feedback control (2005) (51)
A combined in vivo neurochemical and electrophysiological analysis of the effect of high-frequency stimulation of the subthalamic nucleus on 5-HT transmission (2012) (50)
Pindolol occupancy of 5‐HT1A receptors measured in vivo using small animal positron emission tomography with carbon‐11 labeled WAY 100635 (2000) (50)
Attenuation of some subjective effects of amphetamine following tyrosine depletion (1999) (49)
Different tonic regulation of neuronal activity in the rat dorsal raphe and medial prefrontal cortex via 5-HT1A receptors (2001) (47)
Differential pulse voltammetry: simultaneous in vivo measurement of ascorbic acid, catechols and 5-hydroxyindoles in the rat striatum (1984) (46)
Evidence that genetic variation in 5-HT transporter expression is linked to changes in 5-HT2A receptor function (2008) (44)
Effects of repeated administration of 3,4-methylenedioxymethamphetamine on 5-hydroxytryptamine neuronal activity and release in the rat brain in vivo. (1996) (44)
Rapid Postmortem Increase in Extracellular Dopamine in the Rat Brain as Assessed by Brain Microdialysis (1988) (44)
Striato-nigral dynorphin and substance P pathways in the rat (1986) (43)
Glutamate receptor activation is involved in 5-HT2 agonist-induced Arc gene expression in the rat cortex (2004) (42)
Fenfluramine evokes 5‐HT2A receptor‐mediated responses but does not displace [11C]MDL 100907: Small animal PET and gene expression studies (2003) (42)
A comparison of the locomotor effects induced by centrally injected TRH and TRH analogues (1984) (41)
High frequency stimulation of the subthalamic nucleus increases c-fos immunoreactivity in the dorsal raphe nucleus and afferent brain regions. (2011) (41)
Affinity of (±)‐Pindolol, (‐)‐Penbutolol, and (‐)‐Tertatolol for Pre‐ and Postsynaptic Serotonin 5‐HT1A Receptors in Human and Rat Brain (2000) (40)
Nicotine inhibits firing activity of dorsal raphe 5-HT neurones in vivo (2000) (39)
8-OH-DPAT-induced release of hippocampal noradrenaline in vivo: evidence for a role of both 5-HT1A and dopamine D1 receptors. (1996) (39)
In vitro evidence that 5‐hydroxytryptamine increases efflux of glial glutamate via 5‐HT2A receptor activation (2002) (39)
Analeptic effects of centrally injected TRH and analogues of TRH in the pentobarbitone-anaesthetized rat (1984) (38)
Use of Arc expression as a molecular marker of increased postsynaptic 5‐HT function after SSRI/5‐HT1A receptor antagonist co‐administration (2003) (38)
Increased Serotonin Transporter Expression Reduces Fear and Recruitment of Parvalbumin Interneurons of the Amygdala (2015) (37)
Acute effects of 3,4-methylenedioxymethamphetamine (MDMA) on 5-HT cell firing and release: Comparison between dorsal and median raphe 5-HT systems (1997) (37)
Effect of dopamine D-1 and D-2 receptor selective drugs on dopamine release and metabolism in rat striatum in vivo (1986) (37)
Fornix deep brain stimulation enhances acetylcholine levels in the hippocampus (2015) (36)
Effect of short- and long-term administration of lithium on the release of endogenous 5-HT in the hippocampus of the rat in vivo and in vitro (1991) (36)
Effect of sulpiride on amphetamine-induced behaviour in relation to changes in striatal dopamine release in vivo. (1986) (35)
Increased electrical and metabolic activity in the dorsal raphe nucleus of Parkinsonian rats (2008) (35)
Burst-firing activity of presumed 5-HT neurones of the rat dorsal raphe nucleus: electrophysiological analysis by antidromic stimulation (1996) (35)
Repeated administration of fluoxetine, desipramine and tranylcypromine increases dopamine D2-like but not D1-like receptor function in the rat (1998) (34)
A manually-operated brain tissue slicer suitable for neurotransmitter release studies (1983) (34)
A 5-hydroxytryptamine lesion markedly reduces the incidence of burst-firing dorsal raphe neurones in the rat (1996) (34)
Selective 5-HT1A and 5-HT2 receptor-mediated adrenocorticotropin release in the rat: effect of repeated antidepressant treatments. (1992) (33)
GluN1 hypomorph mice exhibit wide-ranging behavioral alterations (2012) (33)
Effect of acute and repeated administration of 5-HT1A receptor agonists on 5-HT release in rat brain in vivo (1993) (32)
Restoration of function to the denervated spinal cord after implantation of embryonic 5HT- and substance P-containing raphe neurones. (1990) (32)
Simultaneous blockade of 5-HT1A/B receptors and 5-HT transporters results in acute increases in extracellular 5-HT in both rats and guinea pigs: in vivo characterization of the novel 5-HT1A/B receptor antagonist/5-HT transport inhibitor SB-649915-B (2007) (32)
Expression of 5-HT receptors and the 5-HT transporter in rat brain after electroconvulsive shock (1999) (32)
d‐amino acid oxidase knockout (Dao −/−) mice show enhanced short‐term memory performance and heightened anxiety, but no sleep or circadian rhythm disruption (2015) (31)
Spike-timing relationship of neurochemically-identified dorsal raphe neurons during cortical slow oscillations (2011) (31)
Non‐linear relationship between 5‐HT transporter gene expression and frequency sensitivity of 5‐HT signals (2010) (31)
Intracerebral dialysis coupled to a novel activity box — a method to monitor dopamine release during behaviour (1986) (30)
Evidence that the large neutral amino acidl-valine decreases electrically-evoked release of 5-HT in rat hippocampus in vivo (2005) (30)
High-frequency stimulation of the subthalamic nucleus inhibits the firing of juxtacellular labelled 5-HT-containing neurones (2011) (30)
S32212, a Novel Serotonin Type 2C Receptor Inverse Agonist/α2-Adrenoceptor Antagonist and Potential Antidepressant: II. A Behavioral, Neurochemical, and Electrophysiological Characterization (2012) (29)
The role of 5-HT1A autoreceptors and α 1-Adrenoceptors in the inhibition of 5-HT release—II NAN-190 and SDZ 216-525 (1996) (29)
Intracellular recordings from burst-firing presumed serotonergic neurones in the rat dorsal raphe nucleus in vivo (1996) (29)
GABA and mood disorders (2003) (28)
Evidence that the enhancement of dopamine function by repeated electroconvulsive shock requires concomitant activation of D1-like and D2-like dopamine receptors (1997) (28)
Modulation of hippocampal dopamine metabolism and hippocampal-dependent cognitive function by catechol-O-methyltransferase inhibition (2012) (28)
Evidence That Increased 5-HT Release Evokes Region-Specific Effects on Blood-Oxygenation Level-Dependent Functional Magnetic Resonance Imaging Responses in the Rat Brain (2009) (28)
p-Chloroamphetamine (PCA), 3,4-methylenedioxymethamphetamine (MDMA) andd-fenfluramine pretreatment attenuatesd-fenfluramine-evoked release of 5-HT in vivo (1994) (27)
Variation in Serotonin Transporter Expression Modulates Fear-Evoked Hemodynamic Responses and Theta-Frequency Neuronal Oscillations in the Amygdala (2014) (27)
Effect of 5‐HT1A receptor ligands on Fos‐like immunoreactivity in rat brain: Evidence for activation of noradrenergic transmission (1999) (26)
Structural and functional analysis of raphe neurone implants into denervated rat spinal cord (1989) (26)
Reduced sensitivity to both positive and negative reinforcement in mice over‐expressing the 5‐hydroxytryptamine transporter (2014) (25)
Pharmacological evidence that 5-HT2C receptor blockade selectively improves decision making when rewards are paired with audiovisual cues in a rat gambling task (2017) (24)
Mice overexpressing the 5-hydroxytryptamine transporter show no alterations in feeding behaviour and increased non-feeding responses to fenfluramine (2008) (24)
The effect of kainic acid on the release of GABA in rat neostriatum and substantia nigra. (1994) (24)
Effects of co-administration of a monoamine oxidase inhibitor and a 5-HT1A receptor antagonist on 5-hydroxytryptamine cell firing and release. (1997) (24)
Tyrosine depletion attenuates the behavioural stimulant effects of amphetamine and cocaine in rats. (2001) (23)
Effects of the 5-HT4 receptor agonist RS67333 and paroxetine on hippocampal extracellular 5-HT levels (2010) (23)
Effect of Acute Tyrosine Depletion in Using a Branched Chain Amino-Acid Mixture on Dopamine Neurotransmission in the Rat Brain (2006) (23)
CONCOMITANT DETERMINATION OF ENDOGENOUS RELEASE OF DOPAMINE, NORADRENALINE, 5-HYDROXYTRYPTAMINE AND THYROTROPHIN RELEASING HORMONE (TRH) FROM RAT BRAIN SLICES AND SYNAPTOSOMES (1981) (23)
Searching for cognitive enhancement in the Morris water maze: better and worse performance in D‐amino acid oxidase knockout (Dao −/−) mice (2016) (22)
In Vivo Measurement Using Microdialysis of the Release and Metabolism of 5‐Hydroxytryptamine in Raphe Neurones Grafted to the Rat Hippocampus (1989) (22)
Molecular and cellular mechanisms of antidepressant action. (2012) (22)
SERT and uncertainty: serotonin transporter expression influences information processing biases for ambiguous aversive cues in mice (2015) (21)
The novel 5‐HT1A receptor antagonist, SDZ 216–525, decreases 5‐HT release in rat hippocampus in vivo (1993) (21)
Pharmacological Evidence for 5-HT6 Receptor Modulation of 5-HT Neuron Firing in Vivo. (2015) (20)
Neurovascular and neuroimaging effects of the hallucinogenic serotonin receptor agonist psilocin in the rat brain (2015) (20)
Effect of different 5-HT1A receptor antagonists in combination with paroxetine on expression of the immediate–early gene Arc in rat brain (2003) (19)
Parkinson's disease, DBS and suicide: a role for serotonin? (2009) (19)
Ebselen has lithium‐like effects on central 5‐HT2A receptor function (2018) (19)
Molecular adaptation to chronic antidepressant treatment: evidence for a more rapid response to the novel α₂-adrenoceptor antagonist/5-HT-noradrenaline reuptake inhibitor (SNRI), S35966, compared to the SNRI, venlafaxine. (2012) (19)
A Model of Post-Infection Fatigue Is Associated with Increased TNF and 5-HT2A Receptor Expression in Mice (2015) (19)
Critical issues in the antisense inhibition of brain gene expression in vivo: Experiences targetting the 5-HT1A receptor (1997) (18)
Electroconvulsive shock increases dopamine D1 and D2 receptor mRNA in the nucleus accumbens of the rat (1995) (18)
The D-2 agonist quinpirole releases striatal dopamine in vivo. (1987) (18)
Genetic variation in 5-hydroxytryptamine transporter expression causes adaptive changes in 5-HT₄ receptor levels. (2012) (17)
Fos immunocytochemical studies on the neuroanatomical sites of action of acute tyrosine depletion in the rat brain (2004) (17)
The putative lithium-mimetic ebselen reduces impulsivity in rodent models (2018) (17)
Region‐specific effects of a tyrosine‐free amino acid mixture on amphetamine‐induced changes in BOLD fMRI signal in the rat brain (2007) (17)
Shared changes in gene expression in frontal cortex of four genetically modified mouse models of depression (2011) (17)
In vivo monoamine release during naloxone-precipitated morphine withdrawal. (1993) (16)
Genotype-Dependent Effects of COMT Inhibition on Cognitive Function in a Highly Specific, Novel Mouse Model of Altered COMT Activity (2016) (16)
Tyrosine‐free amino acid mixture attenuates amphetamine‐induced displacement of [11C]raclopride in striatum in vivo: A rat PET study (2004) (16)
Systemic inflammation alters central 5-HT function as determined by pharmacological MRI (2013) (16)
Decreased striatal dopamine in group II metabotropic glutamate receptor (mGlu2/mGlu3) double knockout mice (2013) (15)
Increased burst‐firing of ventral tegmental area dopaminergic neurons in d‐amino acid oxidase knockout mice in vivo (2014) (15)
EFFECT OF AMINO-ACID LOADS ON HIPPOCAMPAL 5-HT RELEASE INVITRO EVOKED BY ELECTRICAL-STIMULATION OF THE DORSAL RAPHE NUCLEUS AND D-FENFLURAMINE ADMINISTRATION (1992) (15)
Electrical stimulation of the dorsal and median raphe nuclei increases extracellular noradrenaline in rat hippocampus: Evidence for a 5-HT-independent mechanism (2002) (14)
The TRH analogue CG3509 increases in vivo catechol/ascorbate oxidation in the n. accumbens but not in the striatum of the rat (1984) (14)
High-Frequency Stimulation of the Substantia Nigra Induces Serotonin-Dependent Depression-Like Behavior in Animal Models (2013) (14)
Electrochemical monitoring of 5-hydroxytryptamine release in vitro and related in vivo measurements of indoleamines. (1981) (14)
D-amino acid oxidase is expressed in the ventral tegmental area and modulates cortical dopamine (2014) (14)
An investigation of the origin of extracellular GABA in rat nucleus accumbens measuredin vivo by microdialysis (2005) (14)
Determination of dopamine and its metabolites in small volumes of rat brain dialysates using small-bore liquid chromatography with electrochemical detection. (1986) (14)
Clonidine but not nifedipine prevents the release of noradrenaline during naloxone-precipitated opiate withdrawal: an in vivo microdialysis study in the rat (2005) (14)
Behavioural and neuroendocrine responses to D-fenfluramine in rats treated with neurotoxic amphetamines (1995) (13)
Enhancement of dopamine-mediated behaviour by the NMDA antagonists MK-801 and CPP: similarities with repeated electroconvulsive shock (1997) (13)
Effects of subchronic haloperidol and sulpiride on regional brain dopamine metabolism in the rat. (1986) (13)
Serotonergic Feedback Control (2010) (13)
Tyrosine-free amino acid mixtures reduce physiologically-evoked release of dopamine in a selective and activity-dependent manner (2014) (13)
A New Molecule to Brighten the Mood (2006) (12)
Enhanced discriminative aversive learning and amygdala responsivity in 5-HT transporter mutant mice (2019) (12)
Behavioral Neurobiology of Depression and Its Treatment (2013) (12)
Differential gene expression in mutant mice overexpressing or deficient in the serotonin transporter: A focus on urocortin 1 (2011) (11)
High‐frequency stimulation of the subthalamic nucleus modulates neuronal activity in the lateral habenula nucleus (2016) (10)
Partial postsynaptic 5-HT1A agonist properties of the novel stereoselective 8-OH-DPAT analogue (+)cis-8-hydroxy-1-methyl-2-(di-n-propylamino)tetralin, (+)ALK-3. (1989) (10)
The novel monoamine reuptake inhibitor and potential antidepressant, S33005, induces Arc gene expression in cerebral cortex. (2004) (10)
Effects of the 5-HT1A partial agonists gepirone, ipsapirone and buspirone on local cerebral glucose utilization in the conscious rat (2005) (10)
Evidence that central 5‐HT2A and 5‐HT2B/C receptors regulate 5‐HT cell firing in the dorsal raphe nucleus of the anaesthetised rat (2003) (10)
Evaluation of the effect of chronic antidepressant treatment on neurokinin-1 receptor expression in the rat brain (2004) (9)
Fos expression in the brains of rats performing an attentional set-shifting task (2010) (9)
Phosphodiesterase 4 inhibition affects both the direct and indirect pathway: an electrophysiological study examining the tri-phasic response in the substantia nigra pars reticulata (2018) (9)
Rapid Measurement of Dopamine Release using Brain Dialysis Combined with Microbore HPLC a (1986) (8)
Electroconvulsive shock increases tachykinin NK(1) receptors, but not the encoding mRNA, in rat cortex. (2001) (8)
Blockade of α2-adrenoceptors induces Arc gene expression in rat brain in a glutamate receptor-dependent manner: A combined qPCR, in situ hybridisation and immunocytochemistry study (2012) (7)
The putative 5-HT1A antagonist BMY 7378 blocks 8-OH-DPAT-induced changes in local cerebral glucose utilization in the conscious rat (1992) (7)
Erratum to “The novel monoamine reuptake inhibitor and potential antidepressant, S33005, induces Arc gene expression in cerebral cortex” [Eur. J. Pharmacol. 489 (2004) 179–185] (2004) (7)
5-HT neurones--bursting with information? (1997) (7)
Repeated ECS enhances dopamine D-1 but not D-2 agonist-induced behavioural responses in rats (2005) (6)
Cerebral oxidative metabolism mapping in four genetic mouse models of anxiety and mood disorders (2019) (6)
Chapter 1.1 What did we learn from microdialysis (2006) (6)
Psilocin acutely alters sleep-wake architecture and cortical brain activity in laboratory mice (2022) (6)
Release of 5-hydroxytryptamine (5-HT) from medullary and mesencephalic raphé neurones after grafting to the rat hippocampus: Evidence for regulation by 5-HT1A autoreceptors (1991) (6)
5-Hydroxytryptamine receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database (2019) (6)
An Early Stage Researcher's Primer on Systems Medicine Terminology (2020) (5)
Studies on the role of calcium in the 5-HT-stimulated release of glutamate from C6 glioma cells. (2002) (5)
Evidence for the differential co-localization of neurokinin-1 receptors with 5-HT receptor subtypes in rat forebrain (2012) (5)
GABA transmission in the ventral pallidum is not involved in the control of latent inhibition in the rat (2003) (4)
Effects of the putative lithium mimetic ebselen on pilocarpine-induced neural activity. (2020) (4)
The role of calcium in the pharmacology of mania (1989) (4)
Neuroscience. A new molecule to brighten the mood. (2006) (4)
Effect of penbutolol on neuroendocrine responses to buspirone and mood in SSRI‐refractory patients: a preliminary study (1999) (4)
Mice over-expressing the 5-HT transporter show evidence of increased central 5-HT2A function (2003) (4)
Striatal Dopamine Transporter Function Is Facilitated by Converging Biology of α-Synuclein and Cholesterol (2021) (4)
The production and analysis of transgenic mice expressing the human serotonin transporter. (2000) (4)
Evaluation of the effect of chronic antidepressant treatment on neurokinin-1 receptor expression in the rat brain. (2004) (3)
Effect of selective serotonin reuptake inhibitor discontinuation on anxiety-like behaviours in mice (2022) (3)
Comparison of the effect of buspirone and 1-(2-pyrimidinyl)-piperazine on cerebral glucose utilization in the rat. (1993) (3)
Naloxone-precipitated release of noradrenaline, but not serotonin or dopamine, is increased in brain during withdrawal in morphine dependent rats: an in vivo microdialysis study (1991) (2)
Electrophysiological evidence for 5-HT2 receptor-mediated control of 5-HT cell firing in the dorsal raphe nucleus of the anaesthetised rat (2001) (2)
Psilocin acutely disrupts sleep and affects local but not global sleep homeostasis in laboratory mice (2021) (2)
Assessing the role of ventral pallidal dopamine and GABA transmission in mediating the behavioural effects of systemic amphetamine in the rat. (2000) (2)
Stereoselective and region-specific induction of immediate early gene expression in rat parietal cortex by blockade of neurokinin 1 receptors (2006) (2)
Pharmacologic characterization of dogmatil. Pre- and postsynaptic effects on dopaminergic receptors (1985) (2)
Analogues of thyrotrophin-releasing hormone (TRH) increase catecholamine metabolism and release in the rat nucleus accumbens in vivo (1981) (2)
Neurobiological effects of increased expression of the 5-HT transporter (2008) (2)
Corrigendum to “Systemic inflammation alters central 5-HT function as determined by pharmacological MRI” [Neuroimage 75 (2013) 177–186] (2014) (1)
Effect of endogenous 5-HT on [C-11]MDL 100907 binding investigated in rat brain using PET (2003) (1)
Effects of the potential lithium-mimetic, ebselen, on impulsivity and emotional processing (2016) (1)
Pharmacological evidence that 5-HT2C receptor blockade selectively improves decision making when rewards are paired with audiovisual cues in a rat gambling task (2017) (1)
Administration of lithium altered mRNA expression of voltage-dependent potassium channel subunits in the rat brain (2000) (1)
Increased burst-firing of identified VTA dopamine neurons and elevated expression of cortical dopamine receptors in DAO knockout mice (2012) (1)
In Vivo Electrophysiological Evidence for the Targeting of 5-HT3 Receptor Expressing Cortical Interneurons by the Novel Multimodal Antidepressant Vortioxetine (2016) (1)
Effect of paroxetine in combination with the 5-HT1A antagonists, NAD-299 and LY 426965, on expression of the immediate early gene arc in the rat brain (2002) (1)
P.240 Investigation of the behavioural effects of paroxetine discontinuation in mice (2020) (1)
Fast scan cyclic voltammetry evidence that 5-HT transporter overexpression impairs the function of 5-HT nerve terminals (2008) (1)
P.6.023 Acute tyrosine depletion reduces catecholamine synthesis in the rat brain (1996) (1)
Cis-(+)-8-OH-1-CH3-DPAT, (+)ALK-3, a novel stereoselective pharmacological probe for characterizing 5-HT release-controlling 5-HT1A autoreceptors (1990) (1)
In vivo evidence that 5-HT1A receptor activation increases Fos expression in GABA neurones of the rat frontal cortex (2004) (1)
Similar effects of 5-HT on glutamate release from cultured C6 glioma cells and glia (1998) (1)
The novel monoamine reuptake inhibitor and potential antidepressant, S33005, induces Arc gene expression in cerebral cortex. (2004) (1)
Title Electrical stimulation alleviates depressive-like behaviors ofrats : investigation of brain targets and potential mechanisms (2015) (1)
Fornix deep brain stimulation enhances acetylcholine levels in the hippocampus (2015) (1)
Effect of calcium channel antagonists on electrically-evoked release of 5-HT in rat hippocampus in vivo as studied by microdialysis (1990) (1)
Evidence that 5-HT2 receptor agonist induced inhibtion of 5-HT cell firing is mediated by central and not peripheral 5-HT2 receptors (2003) (1)
Psychiatric aspects of parkinson’s disease in animal models of deep brain stimulation of the subthalamic nucleus (2012) (1)
Co-Administration of the D-Amino Acid Oxidase Inhibitor, Sodium Benzoate, and D-Serine Increases Firing of Identified Dopamine Neurons in the Rat Ventral Tegmental Area in vivo (2011) (1)
2 The Role of Monoamines in Antidepressant Drug Action (2013) (0)
Erratum: Stereoselective and region-specific induction of immediate early gene expression in rat parietal cortex by blockade of neurokinin 1 receptors (Journal of Psychopharmacology (2006) 20 (570-576) DOI: 10.1177/ 0269881105059327) (2011) (0)
Administration of an Inhibitor Of D-amino Acid Oxidase Increases Extracellular Dopamine in the Rat Prefrontal Cortex in vivo (2011) (0)
Effects of COMT inhibition and clozapine treatment on immediate early gene expression (2004) (0)
P.0554 Effect of paroxetine discontinuation on 5-ht neurochemistry in mice ex vivo and in vivo (2021) (0)
Effect of chronic electroconvulsive shock and antidepressant drugs on mRNA expression of AMPA receptor subunits in the rat brain (2001) (0)
Decreased striatal dopamine in group II metabotropic glutamate receptor (mGlu2/mGlu3) double knockout mice (2013) (0)
An investigation of the effects of electroconvulsive shock on mesolimbic dopamine and amino acid transmitter system (1995) (0)
A neurodevelopmental, glutamatergic model relevant to schizophrenia? MK801-induced apoptosis in the neonatal rat produces molecular changes in the adult brain (2003) (0)
Studies of emotionality in genetic mouse models of altered glutamate or 5-HT function (2010) (0)
“Paradoxical wakefulness” induced by psychedelic 5-methoxy-N,N-dimethyltryptamine in mice (2022) (0)
Immunohistochemical evidence that paroxetine discontinuation in mice is associated with increased activation of 5-HT neurons (2022) (0)
Effect of SSRI discontinuation on anxiety-like behaviours in mice (2021) (0)
Cis-( + )-8-OH-1-CHa-DPAT , ( + ) ALK-3 , a novel stereoselective pharmacological probe (0)
Effect of 5-HT on the release of endogenous glutamate from C6 rat glioma cells (1997) (0)
Infection-associated changes in 5-HT function (2010) (0)
LOCAL APPLICATION OF A D-AMINO ACID OXIDASE (DAO) INHIBITOR IN THE VENTRAL TEGMENTAL AREA INCREASES EXTRACELLULAR DOPAMINE IN THE RAT PREFRONTAL CORTEX IN VIVO (2011) (0)
Degeneracy and stability in neural circuits of dopamine and serotonin neuromodulators: A theoretical consideration (2023) (0)
APPLICATION OF IN VIVO VOLTAMMETRY TO THE DEVELOPMENT OF NEW DRUGS (1984) (0)
Neurochemical Characterisation of Group II Metabotropic Receptor Knockout Mice (2011) (0)
Large-scale network modelling of interactions between prefrontal cortex and dorsal raphe nucleus using SpiNNaker (2017) (0)
Abstracts of papers pharmacological meeting (2006) (0)
P.2.c.013 Effect of the putative lithium-mimetic ebselen on 5-HT neurochemistry in the mouse brain (2013) (0)
Erratum: The novel monoamine reuptake inhibitor and potential antidepressant, S33005, induces Arc gene expression in cerebral cortex (European Journal of Pharmacology (2004) 489 (179-185) DOI: 10.1016/j.ejphar.2004.03.002) (2004) (0)
S.22.04 Depression and suicide following subthalamic stimulation: basic mechanisms (2011) (0)
S.06.04 Can we measure 5-HT release with PET? (2003) (0)
Evidence for co-localisation of neurokinin-1 and 5-HT1A receptors in pat forebrain (2004) (0)
Degeneracy and stability in neural circuits of neuromodulators (2020) (0)
Discriminative aversive learning and amygdala responsivity is enhanced in mice with reduced serotonin transporter activity (2017) (0)
Anxiogenic drugs induce Fos expression in a specific set of forebrain regions in the rat (2001) (0)
Cognition: from receptors to circuitry modulation (2014) (0)
The 5-HT2 agonist DOI increases the expression of the immediate early genes arc, homer, c-fos and zif-268 in rat brain regions ex vivo (2001) (0)
Mood Improvement by Deep Brain Stimulation: Targets and Mechanisms (2014) (0)
P.4.002 Catechol-o-methyltransferase (COMT) influences dopamine metabolism outside of the prefrontal cortex (2011) (0)
NEUROBIOLOGICAL EFFECTS OF ALTERED 5-HT TRANSPORTER EXPRESSION: IMPLICATIONS FOR DEPRESSION AND ANXIETY (2010) (0)
Neurochemical evidence that COMT influences the effect of clozapine on dopamine but not noradrenaline release in prefrontal cortex (2003) (0)
Behavioural characterisation of ebselen; a potential lithium-mimetic (2014) (0)
The effect of inflammation on the central 5-HT system in mood disorders (2012) (0)
The Role of Catechol-O-Methyltransferase (COMT) in Modulating Hippocampal Dopaminergic Metabolism and Behaviour (2010) (0)
The effects of high frequency stimulation of the subthalamic nucleus on mood: a role for the lateral habenula? (2012) (0)
The effect of single and repeated electroconvulsive shock (ECS) on neurokinin 1 receptor gene expression in the rat brain (2000) (0)
In vivo electrophysiological study of the targeting of 5‐HT3 receptor‐expressing cortical interneurons by the multimodal antidepressant, vortioxetine (2022) (0)
Behavioural Characterisation of the D-amino Acid Oxidase (DAO) Knockout Mouse: Heightened Anxiety and Enhanced Short-Term Memory (2014) (0)
Revealing the Dynamic Relationship Between Neural Population Activities in Corticoraphe System (2020) (0)
Relationship between Dorsal Raphe Nucleus Neuronal Population Activity with Cortical Rhythms (2019) (0)
High-density recording of DRN neurons in-vivo (2018) (0)
Effect of chronic electroconvulsive shock and antidepressant drug treatment on VGlut1 mRNA expression in rat brain regions (2003) (0)
Neurokinin-1 receptors on the afferents to the raphe (2005) (0)
S.02.02 Mood effects of DBS of the subthalamic nucleus: a role for 5-HT (2009) (0)
Inositol monophosphatase: drug target or false alarm? (2010) (0)
P.1.a.004 Modulation of presynaptic and postsynaptic plasticity by chronic mild stress and decreased vesicular glutamate transporter VGLUT1 levels (2009) (0)
GABA neurones in the dorsal raphe nucleus - Where are they, what do they look like, and how are they regulated? (2004) (0)
Large scale monitoring of neural activity in dorsal raphe nucleus of freely moving mice (2018) (0)
Chronic antidepressant drug treatment does not alter neurokinin-1 receptor expression in the rat brain regions (2001) (0)
Affinity of beta-adrenoceptor ligands for pre- and post-synaptic 5-HT1A receptors in rat brain (1999) (0)
A large-scale computational modelling study to investigate serotonergic modulation of cortical columnar dynamics (2018) (0)
Repeated neonatal maternal separation affects behaviour and neuropeptide gene expression in the adult rat (2002) (0)
Phosphodiesterase 4 inhibition affects both the direct and indirect pathway: an electrophysiological study examining the tri-phasic response in the substantia nigra pars reticulata (2017) (0)
IN-VIVO EVIDENCE THAT D-FENFLURAMINE RELEASES 5-HT FROM NERVE-TERMINALS OF BOTH THE DORSAL AND MEDIAN RAPHE NUCLEI (1995) (0)
Ebselen as a novel IMPase inhibitor as a lithium mimetic (2014) (0)
A tyrosine-free amino acid mixture attenuates amphetamine-induced displacement of [C-11]raclopride inistriatum: A rat PET study (2003) (0)
P.1.026 Mapping of anxiogenic neuronal profiles induced by the GABA inverse agonist FG-7142 and caffeine using pharmacological magnetic resonance imaging (2010) (0)
Investigation of the turnover rate of 5-HT2A receptors in C6 rat glioma cells using phenoxybenzamine (1996) (0)
Long- and short-range connectivity and neuronal types affect prefrontal dorsal raphe circuit dynamics differently (2020) (0)
Mice that over-express the 5-HT transporter show evidence of region-specific changes in 5-HT neurotransmission (2004) (0)
C.03.01 Cognition: from receptors to circuitry modulation (2014) (0)
P.2.c.001 Determining the CNS effects of ebselen: a potential lithium-mimetic (2015) (0)

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