Tsutomu Suzuki
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Neuroscience
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Biology
Tsutomu Suzuki's Degrees
- PhD Neuroscience University of Tokyo
- Masters Biology University of Tokyo
- Bachelors Biology University of Tokyo
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(Suggest an Edit or Addition)Tsutomu Suzuki's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Direct Involvement of Orexinergic Systems in the Activation of the Mesolimbic Dopamine Pathway and Related Behaviors Induced by Morphine (2006) (490)
- Inhaled Rho kinase inhibitors are potent and selective vasodilators in rat pulmonary hypertension. (2005) (262)
- Chronic Pain Induces Anxiety with Concomitant Changes in Opioidergic Function in the Amygdala (2006) (254)
- Hippocampal epigenetic modification at the brain‐derived neurotrophic factor gene induced by an enriched environment (2011) (181)
- Direct Evidence of Astrocytic Modulation in the Development of Rewarding Effects Induced by Drugs of Abuse (2006) (159)
- Blockade of morphine reward through the activation of κ-opioid receptors in mice (1993) (159)
- Direct evidence for the involvement of brain‐derived neurotrophic factor in the development of a neuropathic pain‐like state in mice (2005) (154)
- Suppression of the morphine‐induced rewarding effect in the rat with neuropathic pain: implication of the reduction in µ‐opioid receptor functions in the ventral tegmental area (2002) (137)
- Usefulness of Antidepressants for Improving the Neuropathic Pain-Like State and Pain-Induced Anxiety through Actions at Different Brain Sites (2008) (134)
- Direct evidence for spinal cord microglia in the development of a neuropathic pain‐like state in mice (2006) (123)
- Direct Evidence for the Involvement of the Mesolimbic κ-Opioid System in the Morphine-Induced Rewarding Effect Under an Inflammatory Pain-Like State (2005) (118)
- Epigenetic transcriptional activation of monocyte chemotactic protein 3 contributes to long-lasting neuropathic pain. (2013) (117)
- Involvement of a spinal brain-derived neurotrophic factor/full-length TrkB pathway in the development of nerve injury-induced thermal hyperalgesia in mice (2002) (108)
- Enhanced IL‐1β production in response to the activation of hippocampal glial cells impairs neurogenesis in aged mice (2010) (105)
- Neuropathic and chronic pain stimuli downregulate central mu-opioid and dopaminergic transmission. (2010) (104)
- Role of δ‐opioid receptor function in neurogenesis and neuroprotection (2006) (103)
- Comparative Pharmacological Profiles of Morphine and Oxycodone under a Neuropathic Pain-Like State in Mice: Evidence for Less Sensitivity to Morphine (2008) (102)
- Memory impairment associated with a dysfunction of the hippocampal cholinergic system induced by prenatal and neonatal exposures to bisphenol-A (2007) (93)
- Change in MicroRNAs Associated with Neuronal Adaptive Responses in the Nucleus Accumbens under Neuropathic Pain (2011) (91)
- Chronic pain‐induced emotional dysfunction is associated with astrogliosis due to cortical δ‐opioid receptor dysfunction (2006) (87)
- Morphine-induced place preference in the CXBK mouse: characteristics of μ opioid receptor subtypes (1993) (85)
- Potent antinociceptive effects of TRK-820, a novel κ-opioid receptor agonist (1999) (82)
- Different roles of μ-, δ- and κ-opioid receptors in ethanol-associated place preference in rats exposed to conditioned fear stress (1999) (78)
- Etonitazene delivered orally serves as a reinforcer for Lewis but not Fischer 344 rats (1992) (77)
- Implication of Activated Astrocytes in the Development of Drug Dependence (2008) (75)
- Effects of the histaminergic system on the morphine-induced conditioned place preference in mice (1995) (75)
- Effects of a newly synthesized κ-opioid receptor agonist, TRK-820, on the discriminative stimulus and rewarding effects of cocaine in rats (2002) (72)
- Mechanisms That Underlie μ-Opioid Receptor Agonist–Induced Constipation: Differential Involvement of μ-Opioid Receptor Sites and Responsible Regions (2013) (69)
- Sleep disturbances in a neuropathic pain-like condition in the mouse are associated with altered GABAergic transmission in the cingulate cortex (2011) (68)
- Protease-Activated Receptor-1 and Platelet-Derived Growth Factor in Spinal Cord Neurons Are Implicated in Neuropathic Pain after Nerve Injury (2005) (67)
- Role of extracellular signal‐regulated kinase in the ventral tegmental area in the suppression of the morphine‐induced rewarding effect in mice with sciatic nerve ligation (2004) (67)
- Involvement of Spinal Protein Kinase Cγ in the Attenuation of Opioid μ-Receptor-Mediated G-Protein Activation after Chronic Intrathecal Administration of [d-Ala2,N-MePhe4,Gly-Ol5]Enkephalin (2001) (66)
- Regulation of inhibin production by rat granulosa cells (1987) (65)
- Modulation of opioidergic system on mecamylamine-precipitated nicotine-withdrawal aversion in rats (2000) (64)
- Long‐lasting change in brain dynamics induced by methamphetamine: enhancement of protein kinase C‐dependent astrocytic response and behavioral sensitization (2005) (64)
- Glutamatergic neurotransmission and protein kinase C play a role in neuron–glia communication during the development of methamphetamine‐induced psychological dependence (2005) (62)
- Enhanced μ-Opioid Responses in the Spinal Cord of Mice Lacking Protein Kinase Cγ Isoform* (2001) (60)
- Molecular Evidence for the Functional Role of Dopamine D3 Receptor in the Morphine-Induced Rewarding Effect and Hyperlocomotion (2003) (60)
- Implication of protein kinase C in the orexin‐induced elevation of extracellular dopamine levels and its rewarding effect (2007) (60)
- The Astrocyte-Targeted Therapy by Bushi for the Neuropathic Pain in Mice (2011) (60)
- Effects of differential modulation of μ-, δ- and κ-opioid systems on bicuculline-induced convulsions in the mouse (2000) (58)
- Morphine, oxycodone, and fentanyl exhibit different analgesic profiles in mouse pain models. (2009) (58)
- Role of delta-opioid receptor function in neurogenesis and neuroprotection. (2006) (58)
- Change in the expression of c-fos in the rat brain following sciatic nerve ligation (2003) (58)
- Neuronal protein kinase Cγ‐dependent proliferation and hypertrophy of spinal cord astrocytes following repeated in vivo administration of morphine (2004) (56)
- Role of central ATP-sensitive potassium channels in the analgesic effect and spinal noradrenaline turnover-enhancing effect of intracerebroventricularly injected morphine in mice (1992) (55)
- Effect of repeated administration of morphine on the activity of extracellular signal regulated kinase in the mouse brain (2002) (54)
- Metabotropic glutamate receptor 5 localized in the limbic forebrain is critical for the development of morphine‐induced rewarding effect in mice (2004) (52)
- Differential modification of the rewarding effects of methamphetamine and cocaine by opioids and antihistamines (2005) (51)
- Differential involvement of spinal protein kinase C and protein kinase A in neuropathic and inflammatory pain in mice (2003) (51)
- MGM-9 [(E)-methyl 2-(3-ethyl-7a,12a-(epoxyethanoxy)-9-fluoro-1,2,3,4,6,7,12,12b-octahydro-8-methoxyindolo[2,3-a]quinolizin-2-yl)-3-methoxyacrylate], a derivative of the indole alkaloid mitragynine: A novel dual-acting μ- and κ-opioid agonist with potent antinociceptive and weak rewarding effects in (2008) (50)
- Chronic pain-induced astrocyte activation in the cingulate cortex with no change in neural or glial differentiation from neural stem cells in mice (2007) (50)
- Possible Pharmacotherapy of the Opioid κ Receptor Agonist for Drug Dependence (2004) (49)
- Prenatal and neonatal exposure to low-dose of bisphenol-A enhance the morphine-induced hyperlocomotion and rewarding effect (2006) (47)
- Implication of dopaminergic projection from the ventral tegmental area to the anterior cingulate cortex in μ‐opioid‐induced place preference (2010) (46)
- Differential effects of μ-, δ- and κ-opioid receptor agonists on the discriminative stimulus properties of cocaine in rats (1997) (46)
- Combined effects of psychostimulants and morphine on locomotor activity in mice. (2004) (46)
- Suppression of enriched environment-induced neurogenesis in a rodent model of neuropathic pain (2008) (45)
- Prenatal and neonatal exposure to bisphenol-A affects the morphine-induced rewarding effect and hyperlocomotion in mice (2004) (45)
- Involvement of dopamine-dependent and -independent mechanisms in the rewarding effects mediated by δ opioid receptor subtypes in mice (1997) (44)
- Differential activation of the μ‐opioid receptor by oxycodone and morphine in pain‐related brain regions in a bone cancer pain model (2013) (44)
- Hippocampal epigenetic modification at the doublecortin gene is involved in the impairment of neurogenesis with aging (2010) (43)
- Direct evidence for the involvement of endogenous β-endorphin in the suppression of the morphine-induced rewarding effect under a neuropathic pain-like state (2008) (42)
- The role of dopamine D1-receptors in morphine-induced hyperlocomotion in mice (1994) (42)
- Usefulness of Olanzapine as an Adjunct to Opioid Treatment and for the Treatment of Neuropathic Pain (2012) (41)
- Blockade of δ-Opioid Receptors Prevents Morphine-Induced Place Preference in Mice (1994) (41)
- Promoting effect of O-ethylmenthol on the percutaneous absorption of ketoprofen (1996) (39)
- Effects of gabapentin on brain hyperactivity related to pain and sleep disturbance under a neuropathic pain‐like state using fMRI and brain wave analysis (2011) (39)
- Multiple Analyses of G-Protein Coupled Receptor (GPCR) Expression in the Development of Gefitinib-Resistance in Transforming Non-Small-Cell Lung Cancer (2012) (38)
- Functional interaction among opioid receptor types: up-regulation of μ- and δ-opioid receptor functions after repeated stimulation of κ-opioid receptors (2004) (37)
- Orally Active Opioid μ/δ Dual Agonist MGM-16, a Derivative of the Indole Alkaloid Mitragynine, Exhibits Potent Antiallodynic Effect on Neuropathic Pain in Mice (2014) (37)
- Genistein, a Phytoestrogen, Attenuates Monocrotaline-Induced Pulmonary Hypertension (2006) (36)
- PRECLINICAL STUDY: Changes in central dopaminergic systems and morphine reward by prenatal and neonatal exposure to bisphenol‐A in mice: evidence for the importance of exposure period (2007) (36)
- Effect of a selective GABAB receptor agonist baclofen on the μ-opioid receptor agonist-induced antinociceptive, emetic and rewarding effects (2005) (36)
- Possible involvement of mu1-opioid receptors in the fentanyl- or morphine-induced antinociception at supraspinal and spinal sites. (2002) (36)
- The pharmacological profile of δ opioid receptor ligands, (+) and (−) TAN-67 on pain modulation (2001) (35)
- The κ opioid system regulates endothelial cell differentiation and pathfinding in vascular development. (2011) (35)
- Involvement of μ- and δ-opioid receptors in the ethanol-associated place preference in rats exposed to foot shock stress (1998) (34)
- Drug interactions in the reinforcing effects of over-the-counter cough syrups (2005) (34)
- A putative sigma1 receptor antagonist NE‐100 attenuates the discriminative stimulus effects of ketamine in rats (2001) (33)
- Modulation of κ-opioidergic systems on mecamylamine-precipitated nicotine-withdrawal aversion in rats (2002) (33)
- Modification of morphine-induced locomotor activity by pertussis toxin: biochemical and behavioral studies in mice (1993) (33)
- Behavioral sensitization to the discriminative stimulus effects of methamphetamine in rats. (2004) (33)
- Effects of diabetes on spontaneous locomotor activity in mice (1994) (33)
- Implication of cyclin‐dependent kinase 5 in the development of psychological dependence on and behavioral sensitization to morphine (2005) (32)
- Intensification of the development of ethanol dependence in mice lacking dopamine D3 receptor (2002) (32)
- Determination of tris(2-ethylhexyl)trimellitate released from PVC tube by LC-MS/MS. (2008) (31)
- Functional changes in dopamine D3 receptors by prenatal and neonatal exposure to an endocrine disruptor bisphenol‐A in mice (2004) (31)
- Involvement of spinal metabotropic glutamate receptor 5 in the development of tolerance to morphine‐induced antinociception (2005) (30)
- Antitussive effects of naltrindole, a selective δ-opioid receptor antagonist, in mice and rats (1993) (30)
- Possible pharmacotherapy of the opioid kappa receptor agonist for drug dependence. (2004) (30)
- Effects of a selective κ-opioid agonist, U-50,488H, on morphine dependence in rats (1989) (29)
- Molecular mechanism of changes in the morphine-induced pharmacological actions under chronic pain-like state: suppression of dopaminergic transmission in the brain. (2004) (29)
- Changes in the rewarding effects induced by tramadol and its active metabolite M1 after sciatic nerve injury in mice (2008) (29)
- Synthesis of a novel 6,14-epoxymorphinan derivative and its pharmacology. (2008) (29)
- Methylxanthines (Caffeine and Theophylline) Blocked Methamphetamine‐induced Conditioned Place Preference in Mice but Enhanced That Induced by Cocaine (1992) (29)
- The D3-receptor agonist (±)-7-hydroxy-N,N-di-n-propyl-2-aminotetralin (7-OH-DPAT) attenuates morphine-induced hyperlocomotion in mice (1995) (29)
- Post‐synaptic action of morphine on glutamatergic neuronal transmission related to the descending antinociceptive pathway in the rat thalamus (2007) (28)
- Changes in G‐protein activity mediated through the stimulation of dopamine and GABA B receptors in the mesolimbic dopaminergic system of morphine‐sensitized mice (2003) (27)
- Involvement of mGluR5 in the ethanol-induced neuropathic pain-like state in the rat (2006) (27)
- Involvement of δ1 and δ2 Opioid Receptor Subtypes in the Development of Physical Dependence on Morphine in Mice (1997) (26)
- Involvement of microglia in the ethanol-induced neuropathic pain-like state in the rat (2007) (26)
- Antisense oligodeoxynucleotide to δ opioid receptors attenuates morphine dependence in mice (1997) (26)
- Role of neuronal NR2B subunit‐containing NMDA receptor‐mediated Ca2+ influx and astrocytic activation in cultured mouse cortical neurons and astrocytes (2006) (26)
- Involvement of dopamine D1 and D2 receptors in the ethanol-associated place preference in rats exposed to conditioned fear stress (1999) (26)
- Involvement of δ-opioid receptors in the effects of morphine on locomotor activity and the mesolimbic dopaminergic system in mice (2005) (26)
- In vitro and antinociceptive profile of HON0001, an orally active NMDA receptor NR2B subunit antagonist (2006) (26)
- Ethanol, But Not the Anxiolytic Drugs Buspirone and Diazepam, Produces a Conditioned Place Preference in Rats Exposed to Conditioned Fear Stress (2000) (25)
- Changes in function of NMDA receptor NR2B subunit in spinal cord of rats with neuropathy following chronic ethanol consumption. (2007) (25)
- Hyperactivity in novel environment with increased dopamine and impaired novelty preference in apoptosis signal-regulating kinase 1 (ASK1)-deficient mice (2010) (25)
- Differential properties between TRK-820 and U-50,488H on the discriminative stimulus effects in rats. (2004) (24)
- Functional interaction among opioid receptor types: up-regulation of mu- and delta-opioid receptor functions after repeated stimulation of kappa-opioid receptors. (2004) (24)
- NMDA receptor antagonists potently suppress the spontaneous withdrawal signs induced by discontinuation of long-term diazepam treatment in Fischer 344 rats (1998) (24)
- Implication of Rho‐associated kinase in the elevation of extracellular dopamine levels and its related behaviors induced by methamphetamine in rats (2003) (23)
- Sensation of Abdominal Pain Induced by Peritoneal Carcinomatosis Is Accompanied by Changes in the Expression of Substance P and &mgr;-Opioid Receptors in the Spinal Cord of Mice (2012) (23)
- Inhibitory effects of SA4503 on the rewarding effects of abused drugs (2014) (23)
- Inhibition of the morphine-induced rewarding effect by direct activation of spinal protein kinase C in mice (2004) (23)
- Possible involvement of μ 2-mediated mechanisms in μ-mediated antitussive activity in the mouse (1993) (23)
- mGlu5 receptor and protein kinase C implicated in the development and induction of neuropathic pain following chronic ethanol consumption. (2007) (23)
- Differential mechanism of G-protein activation induced by endogenous mu-opioid peptides, endomorphin and beta-endorphin. (2002) (22)
- Distinct Relations Among Plasma Concentrations Required for Different Pharmacological Effects in Oxycodone, Morphine, and Fentanyl (2011) (22)
- PRECLINICAL STUDY: BRIEF REPORT: Epigenetic modulation at the CCR2 gene correlates with the maintenance of behavioral sensitization to methamphetamine (2010) (22)
- Mechanism of opioid dependence and interaction between opioid receptors (2001) (22)
- Possible involvement of prolonging spinal µ‐opioid receptor desensitization in the development of antihyperalgesic tolerance to µ‐opioids under a neuropathic pain‐like state (2013) (22)
- Modulation of the decrease in the seizure threshold of pentylenetetrazole in diazepam withdrawn mice by the neurosteroid 5αpregnan‐3α,21‐diol‐20‐one (alloTHDOC) (1997) (21)
- Implication of the descending dynorphinergic neuron projecting to the spinal cord in the (+)-matrine- and (+)-allomatrine-induced antinociceptive effects. (2005) (20)
- Effects of μ-, δ- and κ-opioid receptor agonists on methamphetamine-induced self-injurious behavior in mice (2006) (20)
- Increased phosphorylated-μ-opioid receptor immunoreactivity in the mouse spinal cord following sciatic nerve ligation (2004) (20)
- Deltorphin II enhances extracellular levels of dopamine in the nucleus accumbens via opioid receptor-independent mechanisms. (2004) (20)
- Treatment for psychological dependence on morphine: usefulness of inhibiting NMDA receptor and its associated protein kinase in the nucleus accumbens. (2005) (19)
- G protein‐gated inwardly rectifying potassium (KIR3) channels play a primary role in the antinociceptive effect of oxycodone, but not morphine, at supraspinal sites (2014) (19)
- Differences in the morphine-induced inhibition of small and large intestinal transit: Involvement of central and peripheral μ-opioid receptors in mice. (2016) (19)
- Role of spinal voltage-dependent calcium channel α2δ-1 subunit in the expression of a neuropathic pain-like state in mice (2007) (19)
- Characterization of methadone as a β-arrestin-biased μ-opioid receptor agonist (2016) (19)
- Oxidative stress in methamphetamine-induced self-injurious behavior in mice (2007) (19)
- Role of β-adrenoceptors in the expression of morphine withdrawal signs (1994) (19)
- Syntheses of 4,6'-epoxymorphinan derivatives and their pharmacologies. (2008) (19)
- Baclofen as an Adjuvant Analgesic for Cancer Pain (2009) (19)
- Differential modulation of μ-opioid receptor-mediated antitussive activity by δ-opioid receptor agonists in mice (1993) (18)
- Comparison of the behavioral effects of bupropion and psychostimulants. (2013) (18)
- Up-regulation of spinal μ-opioid receptor function to activate G-protein by chronic naloxone treatment (2001) (18)
- Mice with neuropathic pain exhibit morphine tolerance due to a decrease in the morphine concentration in the brain. (2016) (18)
- Involvement of δ1-opioid receptor antagonism in the antitussive effect of δ-opioid receptor antagonists (1994) (18)
- Generalization of NMDA-receptor antagonists to the discriminative stimulus effects of kappa-opioid receptor agonists U-50,488H, but not TRK-820 in rats. (2006) (17)
- Peripheral Opioid Antagonist Enhances the Effect of Anti-Tumor Drug by Blocking a Cell Growth-Suppressive Pathway In Vivo (2015) (17)
- Oxycodone-Induced Analgesic Effects in a Bone Cancer Pain Model in Mice (2008) (17)
- Disruption of the type 1 inositol 1,4,5-trisphosphate receptor gene suppresses the morphine-induced antinociception in the mouse (2003) (17)
- Synthesis of novel twin drug consisting of 8-oxaendoethanotetrahydromorphides with a 1,4-dioxane spacer and its pharmacological activities: mu, kappa, and putative epsilon opioid receptor antagonists. (2009) (17)
- Establishment of opioid-induced rewarding effects under oxaliplatin- and Paclitaxel-induced neuropathy in rats. (2014) (17)
- Role of the NMDA receptor complex in DMCM‐induced seizure in mice (1997) (17)
- Effects of fluvoxamine on morphine-induced inhibition of gastrointestinal transit, antinociception and hyperlocomotion in mice (2001) (16)
- Effects of mirtazapine on sleep disturbance under neuropathic pain‐like state (2012) (16)
- Implication of endogenous β-endorphin in the inhibition of the morphine-induced rewarding effect by the direct activation of spinal protein kinase C in mice (2008) (16)
- Adrenalectomy potentiates the morphinebut not cocaine-induced place preference in rats (1995) (16)
- Heterologous µ‐opioid receptor adaptation by repeated stimulation of κ‐opioid receptor: up‐regulation of G‐protein activation and antinociception (2003) (15)
- Antisense oligodeoxynucleotide to δ opioid receptors blocks cocaine-induced place preference in mice (1997) (15)
- Modulation of the discriminative stimulus effects of cocaine and methamphetamine by the histaminergic system. (2002) (15)
- Reduced expression of a novel µ‐opioid receptor (MOR) subtype MOR‐1B in CXBK mice: Implications of MOR‐1B in the expression of MOR‐mediated responses (2003) (15)
- Induction of c-fos expression in the mouse brain associated with hyperalgesia induced by intrathecal injection of protein kinase C activator (2004) (15)
- Potentiation of pentazocine conditioned place preference by tripelennamine in rats (2006) (15)
- Activation of central ATP-sensitive potassium channels produces the antinociception and spinal noradrenaline turnover-enhancing effect in mice (2005) (15)
- Changes in Ca2+-dependent protein kinase C isoforms induced by chronic ethanol treatment in mice (2001) (15)
- Role of μ- and δ-opioid receptors in the nucleus accumbens in turning behaviour of rats (2004) (15)
- Sigma‐1 receptor function is critical for both the discriminative stimulus and aversive effects of the kappa‐opioid receptor agonist U‐50488H (2012) (15)
- Direct evidence for the activation of phospholipase Cγ1 by in vivo treatment with morphine in the mouse periaqueductal gray matter (2003) (15)
- Effect of cyclosporine A on the morphine-induced place preference (1993) (14)
- Differential Substitution for the Discriminative Stimulus Effects of 3,4-Methylenedioxymethamphetamine and Methylphenidate in Rats (2014) (14)
- Endomorphin-induced motivational effect: differential mechanism of endomorphin-1 and endomorphin-2. (2002) (14)
- Morphine and oxycodone, but not fentanyl, exhibit antinociceptive effects mediated by G-protein inwardly rectifying potassium (GIRK) channels in an oxaliplatin-induced neuropathy rat model (2014) (14)
- Lack of development of behavioral sensitization to methylphenidate in mice: correlation with reversible astrocytic activation. (2007) (13)
- Lack of the involvement of μ1-opioid receptor subtype on motivational effects induced by the endogenous μ-opioid receptor ligands endomorphin-1 and -2 in the mouse (2001) (13)
- An ATP-sensitive potassium channel blocker abolishes the potentiating effect of morphine on the bicuculline-induced convulsion in mice (2005) (13)
- Effect of chronic ethanol treatment on μ-opioid receptor function, interacting proteins and morphine-induced place preference (2013) (13)
- The contribution of Gi/o protein to opioid antinociception in an oxaliplatin-induced neuropathy rat model. (2014) (13)
- Discriminative stimulus effects of hallucinogenic drugs: a possible relation to reinforcing and aversive effects. (2012) (12)
- Pharmacological profile of TAN‐452, a novel peripherally acting opioid receptor antagonist for the treatment of opioid‐induced bowel syndromes (2018) (12)
- Enhanced GABAergic synaptic transmission at VLPAG neurons and potent modulation by oxycodone in a bone cancer pain model (2015) (12)
- Blockade of mu-opioid receptor-mediated G-protein activation and antinociception by TRK-820 in mice. (2003) (12)
- Effects of mu-, delta- and kappa-opioid receptor agonists on methamphetamine-induced self-injurious behavior in mice. (2006) (12)
- Involvement of serotonin receptor mechanisms in the discriminative stimulus effects of ketamine in rats. (2013) (12)
- Recent Advances in the Search for the -Opioidergic System (2002) (11)
- Changes in central dopaminergic systems with the expression of Shh or GDNF in mice perinatally exposed to bisphenol-A. (2007) (11)
- Usefulness of the dopamine system-stabilizer aripiprazole for reducing morphine-induced emesis. (2007) (11)
- The kappa opioid receptor agonist SA14867 has antinociceptive and weak sedative effects in models of acute and chronic pain. (2011) (11)
- Effects of serotonergic anxiolytics on physical dependence on diazepam in mice (1993) (11)
- Antagonism of the morphine-induced Straub tail reaction by κ-opioid receptor activation in mice (2005) (11)
- Chronic morphine treatment increases the expression of vesicular glutamate transporter 1 in the mouse spinal cord. (2006) (10)
- Role of actin depolymerizing factor in the development of methamphetamine-induced place preference in mice. (2011) (10)
- Reduction in ATP-sensitive potassium channel-mediated antinociception in diabetic mice (2005) (10)
- Activation of extracellular signal‐regulated kinase is critical for the discriminative stimulus effects induced by U‐50,488H (2011) (10)
- The effects of cyclosporine on morphine-induced antinociception in diabetic mice (1993) (10)
- Different effects of NMDA/group I metabotropic glutamate receptor agents in δ- and μ-opioid receptor agonist-induced supraspinal antinociception (2000) (10)
- Suppression of dopamine-related side effects of morphine by aripiprazole, a dopamine system stabilizer. (2008) (10)
- A preliminary study of the effect of naldemedine tosylate on opioid-induced nausea and vomiting (2020) (10)
- Chronic morphine treatment increases the expression of the neural cell adhesion molecule in the dorsal horn of the mouse spinal cord (2006) (10)
- [Exposure to bisphenol-A affects the rewarding system in mice]. (2005) (10)
- Involvement of the K+‐Cl− co‐transporter KCC2 in the sensitization to morphine‐induced hyperlocomotion under chronic treatment with zolpidem in the mesolimbic system (2013) (10)
- Differences in tolerance to anti-hyperalgesic effects between chronic treatment with morphine and fentanyl under a state of pain. (2006) (10)
- Actin dynamics in development of behavioral sensitization after withdrawal from long-term ethanol administration to mice. (2012) (9)
- [Role of astrocytes in rewarding effects of drugs of abuse]. (2006) (9)
- Influence of a deletion of protein kinase Cγ isoform in the G-protein activation mediated through opioid receptor-like-1 and μ-opioid receptors in the mouse pons/medulla (2002) (9)
- Direct Evidence for the Ongoing Brain Activation by Enhanced Dynorphinergic System in the Spinal Cord under Inflammatory Noxious Stimuli (2010) (9)
- Enhancement of glutamatergic transmission in the cingulate cortex in response to mild noxious stimuli under a neuropathic pain‐like state (2011) (9)
- Region-specific changes in [3H]dizocilpine binding in diazepam-withdrawn rats (1998) (9)
- Involvement of supraspinal and peripheral naloxonazine-insensitive opioid receptor sites in the expression of μ-opioid receptor agonist-induced physical dependence. (2013) (9)
- Changes in the melanocortin receptors in the hypothalamus of a rat model of cancer cachexia (2012) (9)
- Enhancement of dopamine-induced signaling responses in the forebrain of mice lacking dopamine D3 receptor (2004) (9)
- Cell-dependent physiological synaptic action of morphine in the rat habenular nucleus: Morphine both inhibits and facilitates excitatory synaptic transmission (2009) (9)
- Implications of Ca2+-activated Cl− channels in the δ-opioid receptor-mediated antinociception in the mouse spinal cord (2000) (9)
- Sleep disturbance associated with an enhanced orexinergic system induced by chronic treatment with paroxetine and milnacipran (2011) (9)
- [The analysis of prescription frequency and the factors on adverse reactions of NSAIDs for post-operative pain in orthopedic patients]. (2003) (8)
- Role of dopamine D2 and D3 receptors in mediating the U‐50,488H discriminative cue: comparison with methamphetamine and cocaine (2012) (8)
- Role of central ATP-sensitive potassium channels in the hyperthermic effect of morphine in mice (2005) (8)
- Role of Src family kinase in the rewarding effect and hyperlocomotion induced by morphine (2006) (8)
- Effects of (+)‐pentazocine on the antinociceptive effects of (–)‐pentazocine in mice (2015) (8)
- Role of gap junction in the expression of morphine-induced antinociception. (2006) (8)
- Implication of spinal protein kinase Cγ isoform in activation of the mouse brain by intrathecal injection of the protein kinase C activator phorbol 12,13-dibutyrate using functional magnetic resonance imaging analysis (2008) (8)
- Effect of pretreatment with pertussis toxin on the development of physical dependence on morphine (1993) (8)
- Involvement of the arachidonic acid cascade in the hypersusceptibility to pentylenetetrazole-induced seizure during diazepam withdrawal. (2012) (8)
- Upregulation of bradykinin receptors is implicated in the pain associated with caerulein‐induced acute pancreatitis (2011) (8)
- Preference for cocaine by the weight pulling method in rats (1990) (8)
- Involvement of histaminergic system in the discriminative stimulus effects of morphine. (2004) (8)
- Agonist and antagonist properties of dihydroetorphine for μ-opioid receptors in mice (1996) (7)
- Effects of Prenatal and Neonatal Exposure to Bisphenol A on the Development of the Central Nervous System (2010) (7)
- Narcolepsy-like sleep disturbance in orexin knockout mice are normalized by the 5-HT1A receptor agonist 8-OH-DPAT (2016) (7)
- Antitussive effects of μ- and κ-agonists in diabetic rats (1993) (7)
- Olanzapine suppresses the rewarding and discriminative stimulus effects induced by morphine (2012) (7)
- Role of spinal voltage-dependent calcium channel alpha 2 delta-1 subunit in the expression of a neuropathic pain-like state in mice. (2007) (7)
- μ-Opioid receptor-independent fashion of the suppression of sodium currents by μ-opioid analgesics in thalamic neurons (2009) (7)
- Effects of flunarizine and diltiazem on physical dependence on barbital in rats (1993) (7)
- [Differences in neuronal toxicity and its molecular mechanisms between methamphetamine and methylphenidate]. (2009) (6)
- Implication of Src family kinase-dependent phosphorylation of NR2B subunit-containing NMDA receptor in the rewarding effect of morphine. (2006) (6)
- Subdiaphragmatic vagotomy increases the sensitivity of lumbar Aδ primary afferent neurons along with voltage‐dependent potassium channels in rats (2012) (6)
- Preventive effects of naldemedine, peripherally acting μ-opioid receptor antagonist, on morphine-induced nausea and vomiting in ferrets. (2020) (5)
- Effects of dronabinol on morphine‐induced dopamine‐related behavioral effects in animals (2012) (5)
- Delta Opioid Receptor–Mediated Antinociception/ Analgesia (2003) (5)
- Involvement of μ‐ and δ‐opioid receptor function in the rewarding effect of (±)‐pentazocine (2015) (5)
- Effect of p-chlorophenylalanine on diazepam withdrawal signs in rats (2004) (5)
- Region-dependent G-protein activation by κ-opioid receptor agonists in the mouse brain (2004) (5)
- Role of mu- and delta-opioid receptors in the nucleus accumbens in turning behaviour of rats. (2004) (5)
- Interaction between mu and kappa receptors in pharmacological effects of tolerance to and dependence on several opioids (1990) (4)
- Genetic background influences nicotine-induced conditioned place preference and place aversion in mice. (2014) (4)
- Enhancement of the rewarding effects of 3,4-methylenedioxymethamphetamine in orexin knockout mice (2020) (4)
- The Discriminative Stimulus Properties of Hallucinogenic and Dissociative Anesthetic Drugs. (2016) (4)
- Brain site- and transmitter-dependent actions of methamphetamine, morphine and antipsychotics (2016) (4)
- Direct evidence for the up‐regulation of spinal µ‐opioid receptor function after repeated stimulation of κ‐opioid receptors in the mouse (2003) (4)
- [Difference in tolerance to anti-hyperalgesic effect and its molecular mechanisms between chronic treatment with morphine, fentanyl and oxycodone in a chronic pain-like state]. (2008) (4)
- [Combined spinal-epidural anesthesia for cesarean section in a patient with dilated cardiomyopathy]. (2008) (4)
- Involvement of dopamine D2 receptor signal transduction in the discriminative stimulus effects of the &kgr;-opioid receptor agonist U-50,488H in rats (2013) (4)
- Implication of KCC2 in the sensitization to morphine by chronic ethanol treatment in mice (2014) (4)
- Involvement of sigma 1 receptor in the SSRI-induced suppression of the methamphetamine-induced behavioral sensitization and rewarding effects in mice. (2013) (3)
- Implication of mGlu5 receptor in the enhancement of morphine-induced hyperlocomotion under chronic treatment with zolpidem. (2014) (3)
- Direct evidence for the up-regulation of spinal micro-opioid receptor function after repeated stimulation of kappa-opioid receptors in the mouse. (2003) (3)
- Up-regulation of μ-opioid receptor-mediated G-protein activation in protein kinase Cγ knockout mice following repeated naloxone treatment (2003) (3)
- Corrigendum to ‘Antinociceptive effects of the selective non-peptide δ-opioid receptor agonist TAN-67 in diabetic mice’ [Eur. J. Pharmacol. 276 (1995) 131–135] (1995) (3)
- Subdiaphragmatic vagotomy induces a functional change in visceral Aδ primary afferent fibers in rats (2012) (3)
- [Behavioral analysis of chronic exposure to diphenylarsinic and associated influence on central nervous systems]. (2007) (3)
- Possible involvement of β‐endorphin in a loss of the coordinated balance of μ‐opioid receptors trafficking processes by fentanyl (2011) (3)
- [Psychological stress and rewarding effect of alcohol]. (2002) (3)
- Preferences for opioids by the weight pulling method in rats (1990) (3)
- Rewarding effects of ethanol combined with low doses of morphine through dopamine D1 receptors. (2013) (3)
- Involvement of 5-HT2 receptors in the expression of withdrawal diarrhea in morphine-dependent mice. (2014) (3)
- Role of tyrosine kinase-dependent phosphorylation of NR2B subunit-containing NMDA receptor in morphine reward. (2007) (2)
- Induction of physical dependence on pentobarbital by new infusion method in the rat (1989) (2)
- Chronic Pain Stimuli Downregulate Mesolimbic Dopaminergic Transmission: Possible Mechanism of the Suppression of Opioid Reward (2014) (2)
- INDUCTION OF PHYSICAL DEPENDENCE IN RATS BY SHORT TREATMENT OF MORPHINE-ADMIXED FOOD (1981) (2)
- Role of Inhibins and Activins in Reproduction (1993) (2)
- β-Funaltrexamine Discriminates between Two Subtypes of μ2-Opioid Receptors in Electrically Stimulated Longitudinal Muscle of Guinea Pig Ileum (1998) (2)
- [Effects of fasudil on neuropathic pain-like state in mice]. (2007) (2)
- Enhanced m-Opioid Responses in the Spinal Cord of Mice Lacking Protein Kinase Cg Isoform* (2001) (2)
- TRK-820 , a Selective-Opioid Agonist , Produces Potent Antinociception in Cynomolgus Monkeys (2001) (2)
- Comparison of Anti-Nociceptive and Anti-Inflammatory/Analgesic Effects of Essential Oils in Experimental Animal Models (2014) (2)
- Physical dependence on diazepam in Lewis and Fischer 344 inbred rat strains (1990) (2)
- Region-dependent G-protein activation by kappa-opioid receptor agonists in the mouse brain. (2004) (2)
- [Treatment of Cancer Pain and Medical Narcotics]. (2015) (2)
- Effects of histaminergic drugs on development of analgesic tolerance to morphine in mice (1992) (1)
- [Substance related disorders and addictive disorders]. (2014) (1)
- Comparative pharmacological profiles of oxycodone and morphine in a neuropathic pain-like state in mice (2007) (1)
- BEHAVIORAL CHANGES IN MORPHINE-TOLERANT MICE (1982) (1)
- [Survey on patients' satisfaction with opioid rescue guidance by pharmacists]. (2008) (1)
- Involvement of the Peripheral μ-Opioid Receptor in Tramadol-Induced Constipation in Rodents. (2021) (1)
- Splenectomy modifies hyperactive states of the dopaminergic system induced by morphine in C57BL/6J-bg(J)/bg(J) (beige-J) mice. (2014) (1)
- A new opioid analgesic KT90: Analgesia and dependence liability (1990) (1)
- Diazepam oral self-administration in Lewis and Ficher 344 inbred rat strains (1990) (1)
- G Protein Activation by Endomorphins in the Mouse Periaqueductal Gray Matter (2000) (1)
- [Evaluation method for a pain-like action]. (2007) (1)
- Involvement of spinal G-protein inwardly rectifying potassium (GIRK) channels in the enhanced antinociceptive effects of the activation of both μ-opioid and cannabinoid CB1 receptors. (2022) (1)
- COMPARISON OF PHARMACOLOGICAL PROPERTIES BETWEEN PENTAZOCINE AND HOMOBENZOMORPHAN DERIVATIVES (1981) (1)
- P-44INVOLVEMENT OF MU- AND DELTA-OPIOID RECEPTOR FUNCTION IN THE REWARDING EFFECT OF PENTAZOCINE (2014) (1)
- Dopaminergic hyperactivity accompanied by hyperlocomotion in C57BL/6J-bg(J)/bg(J) (beige-J) mice. (2014) (1)
- The astrocyte-targeted therapy by Bushi for the neuropathic pain (2011) (0)
- Studies on drug dependence (Kept. 135): Sex differences in physical dependence on methaqualone in the rat (1987) (0)
- P-II-A-7 Caffeine's (CAF) Effect on Methamphetamine (MAP), Cocaine (CAN), Morphine(MRP) and Pentobarbital(PTB)-induced Conditioned Place Preference in Mice. 日本動物心理学会第51回大会発表要旨 (1991) (0)
- Synergistic effects of MDMA and ethanol on behavior: Possible effects of ethanol on dopamine D2‐receptor‐related signaling (2020) (0)
- Studies on drug dependence (Rept.100): A study on the quantitative evaluation of drug-seeking behavior for codeine in rats by the weight-pulling method (1983) (0)
- Effects of lipopolysaccharides on dopamine-related behavior of methamphetamine (2014) (0)
- Quantitative trait loci analysis of morphine-induced psychological dependence (2008) (0)
- The advantages of fentanyl for the treatment of pain: Studies of pharmacological profiles and fentanyl relatedside effects (2005) (0)
- Drug against drug addiction (1999) (0)
- Analysis of molecular mechanism underlying the control of ES cell differentiation by the stimulation of dopamine receptors located on embryonic stem cells (2010) (0)
- Studies on drug dependence (Rept. 101): Specificity of the biochemical changes induced by barbital withdrawal (1983) (0)
- [The implication of protein kinase C in the cell-cell interaction during the development of dependence on morphine]. (2006) (0)
- Studies on drug dependence (Rept. 284) : Role of endogenous opioid system in cthanol-induced place preference under foot shock stress in rats (1997) (0)
- Modification of Morphine Dependence under Chronic Pain and Its Mechanism (2002) (0)
- Role of G-protein coupled receptors in the neural differentiation from embryonic stem cells (2010) (0)
- The role of GABAA receptors on ethanol-induced type 1 IP3 receptor up-regulation (2015) (0)
- Chronic pain induces the changes in glial function associated with emotional dysfunction (2007) (0)
- New psychotropic substance abuse and its regulation. (2017) (0)
- STUDIES ON DRUG DEPENDENCE (REPT. 52) INDUCTION OF MORPHINE DEPENDENT MICE BY DAF (DRUG-ADMIXED FOOD) METHOD (1980) (0)
- P-26CHANGE IN ALDEHYDE DEHYDROGENASE BY CHRONIC TREATMENT WITH ETHANOL IN THE MOUSE BRAIN (2014) (0)
- Psychological dependence on opioid analgesics. (2013) (0)
- [Electrophysiological technique--significance as an experimental method for alcoholic study]. (2008) (0)
- Studies on pain control system (Rept. 107): Possible role of the spinal IL-6/C-C chemokine-mediated signaling network in the development of a neuropathic pain-like state in mice (2009) (0)
- Studies on drug dependence (Rept.345): Role of protein kinase Cγ isoform in desensitization of G-protein activation by μ-opioid receptor agonist (2000) (0)
- S9-4 Molecular mechanism of changes in the morphine-induced rewarding effect under chronic pain-like state : Suppression of dopaminergic transmission in the brain(SYMPOSIUM 9: MOLECULAR MECHANISMS OF DRUG DEPENDENCE)(Proceedings of the 31st Annual Meeting) (2004) (0)
- The effect of chronic treatment with naltrindole, a selective δ-opioid antagonist, on μ-opioid receptor-mediated antinociception in diabetic mice (2005) (0)
- Pain clinic and drugs of abuse (2005) (0)
- Studies on drug dependence (Rept. 159): Genetic analysis of reverse tolerances to several drugs in two strains of inbred mice (1989) (0)
- P-II-5 The Effect of Methamphetamine and Caffeine on Place Preference Conditioning(日本動物心理学会第50回大会発表) (1990) (0)
- [Physiological functions of sigma-1 receptors and its relation to psychic dependence]. (2012) (0)
- Clinical Pharmacokinetics of Methadone (2014) (0)
- Enhancement of benzodiazepines on abused drug-induced hyperlocomotion (2014) (0)
- Studies on drug dependence (Rept. 228): Pharmacogenetic analysis of morphine-induced locomotor activity in SMXA mice. (1993) (0)
- The analgesic effect of Bushimatsu via inhibition of astrocytic activaion on neuropathic pain (2010) (0)
- Studies on drug dependence (Rept. 300): Role of NMDA receptor in the appearance of diazepam withdrawal signs (1998) (0)
- [Basic studies on cancer pain control]. (2005) (0)
- STUDIES ON DRUG DEPENDENCE (REPT. 90) TOLERANCE TO METHAMPHETAMINE AND EFFECT OF COMBINATION OF METHAMPHETAMINE AND QUININE (1982) (0)
- Effect of chronic ethanol treatment on μ-opioid receptor function, interacting proteins and morphine-induced place preference (2013) (0)
- Chronic treatment with diphenylarsinic acid (DPAA) affects central nerves system(Proceedings of the 32nd Annual Meeting) (2005) (0)
- Proper use of opioid analgesic (2006) (0)
- of the sciatic nerve by the partial ligation (2000) (0)
- Changes in brain dynamics by chronic pain: Molecular mechanisms of the suppression of morphine-induced rewarding effects and the aggravated anxiety (2006) (0)
- Correction: Multiple Analyses of G-Protein Coupled Receptor (GPCR) Expression in the Development of Gefitinib-Resistance in Transforming Non-Small-Cell Lung Cancer (2013) (0)
- Studies on drug dependence (Rept. 342): Down-regulation of μ-opioid receptor expression is necessary for the suppression of the morphine-induced sensitization by rolipram (2000) (0)
- Role of spinal thrombin and platelet-derived growth factor in the expression of chronic pain-like state in mice (2007) (0)
- Studies on drug dependence (Rept. 211): Establishment of ethanol-induced place preference in rats (1992) (0)
- Study on drug dependence (Rept. 381) : Direct evidence for the up-regulation of central μ-opioid receptor functions induced by repeated stimulation of κ-opioid receptors (2003) (0)
- Remedies for neuropathic pain animal models of neuropathic pain. (2000) (0)
- Studies on pain control system (Rept. 67): Opioids regulate sodium currents in rat cultured thalamic neurons (2007) (0)
- Analysis of sleep disturbance associated with the change in nerve function in the cingulate cortex under neuropathic pain (2011) (0)
- P1–015ACTIONS OF THE SYMPTOM CONTROL RESEARCH GROUP (SCORE-G) IN THE PALLIATIVE CARE FIELD IN JAPAN: REPORT 3 (2013) (0)
- Chronic ethanol treatment alters the central gene-expression profiling along with epigenetic modifications (2010) (0)
- Studies on pain control system (Rept.106): Vagal dysfunction caused nociceptive neuroplasticity (2009) (0)
- Studies on drug dependence (Rept. 323): Changes in methamphetamine (MAP)-induced place preference and discrimination in rats pretreated with MAP. (1999) (0)
- STUDIES ON DRUG DEPENDENCE (REPT. 72) BRAIN MORPHINE LEVELS OF DEPENDENT MICE BY DAF (DRUG-ADMIXED FOOD) METHOD (1981) (0)
- Studies on drug dependence (Rept. 210): Enhancing effects of opioids and antihistamines on psychostimulants-induced place preference in rats (1992) (0)
- Studies on drug dependence (Rept. 322): Attenuation of morphine- and psychostimulants-induced place preference by α1 receptor agonist SA4503. (1999) (0)
- Promotion of the neural differentiation from embryonic stem cells activated by dopamine D3 receptors (2009) (0)
- Molecular mechanism underlying the suppression of the morphine-induced rewarding effect and reduced sensitivity to morphine-induced antinociceptive action under chronic pain-like state (2004) (0)
- Erratum to “Differential involvement of spinal protein kinase C and protein kinase A in neuropathic and inflammatory pain in mice” [Brain Res. 992 (2003) 288–293] (2004) (0)
- Studies on drug dependence (Rept. 260): Anticonflict action of U50.488H (1995) (0)
- Studies on drug dependence (Report 99): Effect of quinine on methamphetamine-induced stereotyped behavior and acute toxicity in rats (1983) (0)
- Studies on pain control system (Rept. 120): Multiplex gene profiling with epigenetic modification in the spinal cord of mice with neuropathic pain (2010) (0)
- [Implication of neuron-glia interaction in the molecular mechanism of drug dependence]. (2008) (0)
- Drug delivery system in pain control Pharmacological characteristics of narcotics (2005) (0)
- [Implication of glial function in the development of drug dependence associated with synaptic plasticity]. (2005) (0)
- Cure for drug addiction (1998) (0)
- Effects of imipramine on physical dependence on barbital in rats (1993) (0)
- Molecular mechanisms underlying the reduced opioid reward assosiated with alteration of microRNA expression and epigenetic modulation under the neuropathic pain (2010) (0)
- The K + -Cl − Cotransporter KCC2 and Zolpidem (2016) (0)
- Studies on drug dependence (Rept. 122): Degree of physical dependence induced by pentobarbital and pentobarbital sodium (1985) (0)
- P-46depletion of orexin affects the discriminative stimulus and rewarding effects of mdma in mice. (2014) (0)
- ATPによる自然”グリオトランスミッションは”培養海馬星状細胞において細胞内シグナリングカスケードのスイッチングオーバーを起こす (2004) (0)
- Studies on pain control system (Rept. 66): Involvement of endogenous opioidergic system in the suppression of the morphine-induced rewarding effect under the neuropathic pain-like state (2007) (0)
- Narcolepsy-like sleep disturbance in orexin knockout mice are normalized by the 5-HT1A receptor agonist 8-OH-DPAT (2016) (0)
- Remedy for neuropathic pain and laboratory animal-models of neuropathic pain (2000) (0)
- Studies on drug dependence (Rept. 274): The role of κ-opioid receptor in morphine-induced place preference under inflammations. (1996) (0)
- Genetic background influences the change from the discriminative stimulus to the rewarding effects of psychostimulants in rats (2015) (0)
- Involvement of mGlu5 receptor signal cascade in the enhancement of morphine-induced hyperlocomotion under chronic treatment with zolpidem (2015) (0)
- Changes in new generation of glial cells under the neuropathic pain like state (2007) (0)
- 1365 – EVALUATION OF INDUCING PHYSICAL DEPENDENCE AND PROMOTING SPONTANEOUS DRUG INTAKE IN CHOICE TRIALS USING DRUG-ADMIXED DIET IN RATS (1977) (0)
- Possible implication of μ-opioid receptors in the neural differentiation from embryonic stem cells (2009) (0)
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What Schools Are Affiliated With Tsutomu Suzuki?
Tsutomu Suzuki is affiliated with the following schools: