Ulrich Klotz
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Medical Philosophy
Ulrich Klotz's Degrees
- PhD Pharmacology University of California, San Francisco
- Doctorate Medicine University of California, San Francisco
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(Suggest an Edit or Addition)Ulrich Klotz's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The effects of age and liver disease on the disposition and elimination of diazepam in adult man. (1975) (644)
- Pharmacokinetics and drug metabolism in the elderly (2009) (612)
- Piperine, a Major Constituent of Black Pepper, Inhibits Human P-glycoprotein and CYP3A4 (2002) (468)
- Extrahepatic Metabolism of Drugs in Humans (1994) (461)
- Telomere length in different tissues of elderly patients (2000) (333)
- Proton pump inhibitors: an update of their clinical use and pharmacokinetics (2008) (295)
- Delayed clearance of diazepam due to cimetidine. (1980) (294)
- Therapeutic efficacy of sulfasalazine and its metabolites in patients with ulcerative colitis and Crohn's disease. (1980) (284)
- Clinical Pharmacokinetics of Sulphasalazine, Its Metabolites and Other Prodrugs of 5-Aminosalicylic Acid (1985) (254)
- The clinical impact of pharmacogenetics on the treatment of epilepsy (2009) (252)
- The clinical implications of ageing for rational drug therapy (2008) (241)
- Clinical Pharmacokinetics and Use of Infliximab (2007) (238)
- Interaction of omeprazole, lansoprazole and pantoprazole with P-glycoprotein (2001) (229)
- Pharmacokinetics and plasma binding of diazepam in man, dog, rabbit, guinea pig and rat. (1976) (227)
- Midazolam kinetics (1981) (219)
- Influence of Diet and Nutritional Status on Drug Metabolism (1996) (210)
- Relative potency of proton-pump inhibitors—comparison of effects on intragastric pH (2008) (210)
- Age-related changes in pharmacokinetics. (2011) (210)
- Pharmacokinetics and bioavailability of sodium valproate (1977) (209)
- CYP2C19 polymorphism and proton pump inhibitors. (2004) (166)
- Drug Interactions with Herbal Medicines (2012) (163)
- Clinical use and pharmacological properties of selective COX-2 inhibitors (2008) (161)
- Glucuronidation of Drugs (1992) (148)
- The Role of Pharmacogenetics in the Metabolism of Antiepileptic Drugs (2007) (147)
- Clinical impact of CYP2C19 polymorphism on the action of proton pump inhibitors: a review of a special problem. (2006) (147)
- Pharmacokinetics and Pharmacodynamics of Propofol in a New Solvent (1997) (142)
- Thiopurine Treatment in Inflammatory Bowel Disease (2007) (135)
- Topical delivery of therapeutic agents in the treatment of inflammatory bowel disease. (2005) (131)
- Pharmacokinetics and Clinical Use of Flumazenil (Ro 15-1788) (1988) (131)
- Pharmacokinetic Considerations in the Treatment of Inflammatory Bowel Disease (2001) (128)
- Disposition and first‐pass metabolism of ethanol in humans: Is it gastric or hepatic and does it depend on gender? (1996) (119)
- Clinical outcome and influencing factors of a new short-term quadruple therapy for Helicobacter pylori eradication: a randomized controlled trial (MACLOR study). (2002) (118)
- Thiopurine treatment in inflammatory bowel disease: clinical pharmacology and implication of pharmacogenetically guided dosing. (2007) (115)
- Tramadol — the Impact of its Pharmacokinetic and Pharmacodynamic Properties on the Clinical Management of Pain (2003) (113)
- Drug metabolism and drug interactions in the elderly. (2001) (113)
- Pharmacokinetic Considerations in the Eradication of Helicobacter Pylori (2000) (111)
- The effect of cirrhosis on the disposition and elimination of meperidine in man (1974) (109)
- Amoxicillin/Metronidazole/Omeprazole/Clarithromycin: A New, Short Quadruple Therapy for Helicobacter pylori Eradication (1998) (108)
- CYP2C19 polymorphism is a major predictor of treatment failure in white patients by use of lansoprazole‐based quadruple therapy for eradication of Helicobacter Pylori (2004) (106)
- Physiologie and temporal variation in hepatic elimination of midazolam (1982) (105)
- Pathophysiological and Disease-Induced Changes in Drug Distribution Volume: Pharmacokinetic Implications (1976) (104)
- Pantoprazole Review of its Pharmacological Properties and Therapeutic Use in Acid-Related Disorders (1996) (103)
- Proximal femur fracture in older patients--rehabilitation and clinical outcome. (2003) (91)
- Influence of Age and Cytochrome P450 2C9 Genotype on the Steady-State Disposition of Diclofenac and Celecoxib (2003) (88)
- Pharmacokinetics and the pharmacodynamic action of midazolam in young and elderly patients undergoing tooth extraction (1998) (88)
- Clinical Pharmacokinetic Considerations in the Use of Plasma Expanders (1987) (86)
- Colonic N-acetylation of 5-aminosalicylic acid in inflammatory bowel disease. (1989) (81)
- Effect of single doses of cimetidine and ranitidine on the steady‐state plasma levels of midazolam (1985) (77)
- Impact of Furazolidone‐Based Quadruple Therapy for Eradication of Helicobacter pylori after Previous Treatment Failures (2002) (76)
- Telomeres in Neonates: New Insights in Fetal Hematopoiesis (2001) (76)
- Delivery and fate of oral mesalamine microgranules within the human small intestine. (1995) (74)
- Possible interaction of fluoroquinolones with the benzodiazepine-GABAA-receptor complex. (1990) (72)
- Interaction of verapamil and cimetidine: stereochemical aspects of drug metabolism, drug disposition and drug action. (1990) (70)
- Ziconotide--a novel neuron-specific calcium channel blocker for the intrathecal treatment of severe chronic pain--a short review. (2006) (70)
- Cimetidine increases steady state plasma levels of propranolol. (1981) (70)
- Inhibition of Terfenadine Metabolism (1994) (70)
- Treatment of Crohn's disease with peroral 5-aminosalicylic acid. (1983) (69)
- Osteoarthritis of the knee--clinical assessments and inflammatory markers. (2004) (69)
- Pharmacodynamic Interaction Between Midazolam and a Specific Benzodiazepine Antagonist in Humans (1985) (69)
- The influence of chitosan content in cationic chitosan/PLGA nanoparticles on the delivery efficiency of antisense 2'-O-methyl-RNA directed against telomerase in lung cancer cells. (2009) (68)
- Site-dependent small intestinal absorption of ranitidine (2004) (67)
- Enzyme induction in the elderly: Effect of rifampin on the pharmacokinetics and pharmacodynamics of propafenone (2000) (67)
- The effect of cirrhosis on the disposition and elimination of meperidine in man. (1975) (67)
- Clinical and toxicological consequences of the inductive potential of ethanol (1998) (67)
- THE EFFECTS OF AGE AND LIVER DISEASE ON THE DISPOSITION AND ELIMINATION OF DIAZEPAM IN ADULT MAN (1976) (66)
- Pharmacokinetic implications for the clinical use of atropine, scopolamine and glycopyrrolate (1988) (63)
- Effects of Celecoxib and Diclofenac on Blood Pressure, Renal Function, and Vasoactive Prostanoids in Young and Elderly Subjects (2002) (60)
- Does pH 6 β-galactosidase activity indicate cell senescence? (1999) (58)
- Drug interaction of herbal tea containing St. John's wort with cyclosporine (2003) (56)
- Stereoselective HPLC-assay for citalopram and its metabolites. (2000) (54)
- Antiarrhythmics: elimination and dosage considerations in hepatic impairment. (2007) (54)
- Gut wall metabolism of verapamil in older people: effects of rifampicin-mediated enzyme induction. (1998) (53)
- P-glycoprotein function in the elderly (2004) (52)
- Disposition of diazepam and its major metabolite desmethyldiazepam in patients with liver disease (1977) (51)
- Pharmacokinetics of Lorcainide in Man: A New Antiarrhythmic Agent (1978) (51)
- A new slow-release form of 5-aminosalicylic acid for the oral treatment of inflammatory bowel disease. Biopharmaceutic and clinical pharmacokinetic characteristics. (1985) (50)
- Lack of pharmacokinetic interaction of pantoprazole with diazepam in man. (1996) (49)
- Oroileal transit of slow release 5-aminosalicylic acid. (1993) (48)
- Effects of cimetidine and ranitidine on steady‐state propranolol kinetics and dynamics (1982) (48)
- The role of aminosalicylates at the beginning of the new millennium in the treatment of chronic inflammatory bowel disease (2000) (48)
- Chronopharmacokinetic Study with Prolonged Infusion of Midazolam (1984) (47)
- Pharmacokinetics of famotidine in man. (1987) (47)
- Improved estimation of glomerular filtration rate by serum cystatin C in preventing contrast induced nephropathy by N-acetylcysteine or zinc--preliminary results. (2007) (47)
- P-glycoprotein-mediated transport of digitoxin, α-methyldigoxin and β-acetyldigoxin (2001) (47)
- Effect of age on pharmacokinetics and pharmacodynamics in man. (1998) (46)
- CIMETIDINE/DIAZEPAM INTERACTION (1979) (46)
- Does the benzodiazepine antagonist Ro 15-1788 antagonize the action of ethanol? (1986) (46)
- CYP2E1 activity in patients with alcoholic liver disease. (1997) (46)
- Intravenous Benzodiazepines as Anaesthetic Agents: Pharmacokinetics and Clinical Consequences (1982) (45)
- Detection of desmethyldiazepam and diazepam in brain of different species and plants. (1989) (45)
- Effects of aminosalicylates on thiopurine S‐methyltransferase activity: an ex vivo study in patients with inflammatory bowel disease (2005) (44)
- Lack of drug interaction between omeprazole, lansoprazole, pantoprazole and theophylline. (1999) (42)
- Biopharmaceutical Characterization of the Telomerase Inhibitor BRACO19 (2006) (42)
- Esomeprazole-induced healing of gastroesophageal reflux disease is unrelated to the genotype of CYP2C19: evidence from clinical and pharmacokinetic data. (2005) (42)
- Altered elimination of desmethyldiazepam in the elderly. (1979) (42)
- Ivermectin binds avidly to plasma proteins (2004) (41)
- The drug interaction potential of ranitidine: an update. (1991) (41)
- Hepatic expression of galectin-3 and receptor for advanced glycation end products in patients with liver disease (2006) (40)
- Protein binding and ivermectin estimations in patients with onchocerciasis (1993) (40)
- High-performance liquid chromatographic determination of aminosalicylate, sulfapyridine and their metabolites. Its application for pharmacokinetic studies with salicylazosulfapyridine in man. (1979) (39)
- Sensitive quantification of omeprazole and its metabolites in human plasma by liquid chromatography-mass spectrometry. (2006) (39)
- Paracetamol (Acetaminophen) – a Popular and Widely Used Nonopioid Analgesic (2012) (39)
- Elevation of steady‐state diazepam levels by cimetidine (1981) (39)
- Flunitrazepam and lormetazepam do not affect the pharmacokinetics of the benzodiazepine antagonist Ro 15-1788. (1985) (39)
- Occurrence of "natural" benzodiazepines. (1991) (39)
- Pharmacokinetics and Pharmacodynamics of H2-Receptor Antagonists in Patients with Renal Insufficiency (1993) (38)
- Effect of five structurally diverse H2-receptor antagonists on drug metabolism. (1986) (38)
- Simple and sensitive method for the determination of celecoxib in human serum by high-performance liquid chromatography with fluorescence detection. (2002) (38)
- Role of Organic Anion-Transporting Polypeptides for Cellular Mesalazine (5-Aminosalicylic Acid) Uptake (2011) (37)
- Disposition of valproic acid in patients with liver disease (1978) (36)
- Pharmacokinetics and pharmacodynamics of cisapride in patients undergoing hemodialysis (1991) (36)
- No Evidence of a Genetic Polymorphism in the Oxidative Metabolism of Midazolam (1988) (36)
- Pharmacokinetics of Na2B12H11SH (BSH) in patients with malignant brain tumours as prerequisite for a phase I clinical trial of boron neutron capture (2005) (35)
- When Are Bioavailability Studies Required? A German Proposal (1998) (35)
- Colonic targeting of aminosalicylates for the treatment of ulcerative colitis. (2005) (35)
- Pharmacokinetics and dynamics of famotidine in patients with renal failure. (1988) (35)
- Psychotropic drug use, falls and hip fracture in the elderly (2000) (34)
- Determination of ivermectin in human plasma by high-performance liquid chromatography. (1993) (34)
- Disposition of diazepam and its major metabolite desmethyldiazepam in patients with liver disease. (1978) (34)
- Treatment and dosing of Helicobacter pylori infection: when pharmacology meets clinic (2007) (33)
- Simplified high-performance liquid chromatographic method for 5-aminosalicylic acid in plasma and urine. (1981) (33)
- Negligible excretion of 5-aminosalicylic acid in breast milk (1993) (33)
- Omeprazole‐induced increase in the absorption of bismuth from tripotassium dicitrato bismuthate (1994) (33)
- Use of Aminoglycosides in Elderly Patients (1997) (32)
- Alterations in the disposition of differently cleared drugs in patients with cirrhosis (1979) (32)
- Occurrence of 'natural' diazepam in human brain. (1990) (30)
- Disposition and antiarrhythmic effect of lorcainide. (1979) (30)
- Generation of Pharmacokinetic Data During Routine Therapeutic Drug Monitoring: Bayesian Approach vs. Pharmacokinetic Studies (1993) (30)
- Disposition of Ibuprofen in Patients with Liver Cirrhosis (1993) (29)
- Characterization of multiple cyclic nucleotide phosphodiesterase activities of rat adipose tissue (1972) (28)
- Lack of effect of nizatidine on drug metabolism. (1987) (28)
- Variability in response to cardiovascular drugs. (2006) (27)
- Tissue slice model of human lung cancer to investigate telomerase inhibition by nanoparticle delivery of antisense 2'-O-methyl-RNA. (2011) (26)
- Nanoparticle mediated delivery of 2'-O-methyl-RNA leads to efficient telomerase inhibition and telomere shortening in human lung cancer cells. (2010) (26)
- Haemodilution therapy in ischaemic stroke: Plasma concentrations and plasma viscosity during long-term infusion of dextran 40 or hydroxyethyl starch 200/0.5 (2004) (26)
- Optimization of the TRAP assay to evaluate specificity of telomerase inhibitors (2005) (26)
- P-glycoprotein-mediated transport of digitoxin, alpha-methyldigoxin and beta-acetyldigoxin. (2001) (26)
- Newer H2-Receptor Antagonists (1988) (26)
- FLUMAZENIL AND HEPATIC ENCEPHALOPATHY (1989) (25)
- Pharmacokinetics of the selective benzodiazepine antagonist Ro 15-1788 in man (2004) (25)
- Influence of cimetidine on the pharmacokinetics of desmethyldiazepam and oxazepam (1980) (25)
- Pharmacokinetics of ketanserin in man (2004) (25)
- Age‐dependent eradication of Helicobacter pylori with dual therapy (1997) (25)
- Esomeprazole‐induced healing of gastroesophageal reflux disease is unrelated to the genotype of CYP2C19: Evidence from clinical and pharmacokinetic data (2005) (24)
- Lansoprazole does not affect the bioavailability of oral contraceptives. (1994) (24)
- Specific measurement of 5-aminosalicylic acid and its acetylated metabolite in human bile. (1983) (24)
- Impact of CYP2C19 polymorphisms on the clinical action of proton pump inhibitors (PPIs) (2008) (24)
- Pharmacological Comparison of the Statins (2003) (24)
- Thiopurine S-methyltransferase as a target for drug interactions (2005) (24)
- Comparison of the pharmacokinetics of diazepam after single and subchronic doses (1976) (24)
- High-performance liquid chromatographic assay with fluorometric detection of ketanserin, a new antihypertensive agent and serotonin S2 antagonist in human plasma, blood and urine. (1983) (24)
- Pharmacokinetic Optimisation of the Treatment of Peptic Ulcer in Patients with Renal Failure (1994) (23)
- Famotidine. Pharmacokinetic properties and suppression of acid secretion in paediatric patients following cardiac surgery. (1990) (23)
- Pharmacology and pharmacokinetics of 5-aminosalicylic acid (1987) (23)
- Pharmacokinetics and effects on intracranial pressure of sufentanil in head trauma patients. (1994) (23)
- The Pharmacological Profile and Clinical Use of Mesalazine (5-Aminosalicylic Acid) (2012) (22)
- Drug interactions and clinical pharmacokinetics of flumazenil. (1988) (21)
- Is N-acetylation of 5-aminosalicylic acid reversible in man? (1984) (21)
- Pharmacokinetics of the selective benzodiazepine antagonist Ro 15-1788 in man (2004) (21)
- Characterization of peripheral-type benzodiazepine binding sites on human lymphocytes and lymphoma cell lines and their role in cell growth. (1992) (21)
- Dyspeptic symptoms associated with Helicobacter pylori infection are influenced by strain and host specific factors (2004) (21)
- Is plasma level monitoring of sulfasalazine indicated in the treatment of Crohn's disease or ulcerative colitis? (1980) (21)
- Pharmacokinetics of midazolam in relation to polymorphic sparteine oxidation. (1986) (20)
- The elderly—a challenge for appropriate drug treatment (2008) (20)
- Interaction Potential of Lercanidipine, a New Vasoselective Dihydropyridine Calcium Antagonist (2002) (19)
- Oral 5‐Aminosalicylic Acid in Children with Colonic Chronic Inflammatory Bowel Disease: Clinical and Pharmacokinetic Experience (1989) (19)
- Is cyclosporin A an inhibitor of drug metabolism? (1990) (19)
- Determination of sulfapyridine and its major metabolites in plasma by high pressure liquid chromatography. (1978) (19)
- Tripotassium dicitrato bismuthate: absorption and urinary excretion of bismuth in patients with normal and impaired renal function (1991) (18)
- Does pH 6 beta-galactosidase activity indicate cell senescence? (1999) (18)
- Screening of telomerase inhibitors. (2007) (18)
- Frequent non-response to histamine H2-receptor antagonists in cirrhotics. (1989) (17)
- EXPRESSION OF INTESTINAL DRUG-METABOLIZING ENZYMES IN PATIENTS WITH CHRONIC INFLAMMATORY BOWEL DISEASE (1998) (17)
- Efficient telomerase inhibition in human non-small cell lung cancer cells by liposomal delivery of 2'-O-methyl-RNA. (2009) (17)
- Effect of omeprazole on nocturnal intragastric pH in cirrhotics with inadequate antisecretory response to ranitidine. (1991) (17)
- Bioavailability of a slow-release preparation of valproic acid under steady-state conditions. (1982) (17)
- Pharmacokinetic studies with valproic acid in man. (1977) (17)
- Telomerase Activity in Cell Lines of Pediatric Soft Tissue Sarcomas (2003) (16)
- Inhibitory effect of omeprazole on the metabolism of midazolam in vitro. (1990) (16)
- Comparative effects of H2-receptor antagonists on drug metabolism in vitro and in vivo. (1987) (16)
- Effect of midazolam on sleep. (1983) (15)
- Disposition of 5-aminosalicylic acid, the active metabolite of sulphasalazine, in man (2004) (15)
- Stereoselective steady state disposition and action of propafenone in Chinese subjects. (1998) (15)
- Tumorigenic conversion of endothelial cells. (2003) (15)
- Valproic acid in childhood epilepsy: anticonvulsive efficacy in relation to its plasma levels. (1980) (15)
- Benzodiazepines: Are They of Natural Origin? (2004) (15)
- Nocturnal Doses of Ranitidine and Nizatidine Do not Affect the Disposition of Diazepam (1987) (14)
- Flumazenil disposition and elimination in cirrhosis (1989) (13)
- Drug Interactions Through Binding to Cytochrome P 450: The Experience with H2-Receptor Blocking Agents (1984) (13)
- Flumazenil disposition and elimination in cirrhosis. (1990) (13)
- Biliary excretion studies with digoxin in man. (1977) (13)
- Decomposition of the telomere-targeting agent BRACO19 in physiological media results in products with decreased inhibitory potential. (2008) (13)
- Clinical Efficacy of Oral Mesalazine in Crohn’s Disease (1990) (12)
- Nizatidine (300 mg nocte) does not interfere with diazepam pharmacokinetics in man. (1987) (12)
- [Drug interactions. Mechanisms and clinical relevance]. (2003) (12)
- Prevention of falls in elderly people (1999) (12)
- Lack of effect of nitrendipine on the pharmacokinetics and pharmacodynamics of midazolam during steady state. (1988) (12)
- Transport studies with 5-aminosalicylate (2006) (12)
- Unchanged serum levels of advanced glycation endproducts in patients with liver disease (2007) (12)
- Proton Pump Inhibitors – Their Pharmacological Impact on the Clinical Management of Acid-Related Disorders (2009) (12)
- Effect of Aging on the Pharmacokinetics of Gastrointestinal Drugs (2003) (11)
- Stability of leukotrienes C4 and D4 in human urine. (1987) (11)
- Telomerase Activity in Chronic Inflammatory Bowel Disease (2003) (11)
- Interactions of analgesics with other drugs. (1983) (11)
- Endogenous benzodiazepines in brain: right or wrong? (1988) (11)
- Telomeres and telomerase in paediatric patients with T-cell acute lymphoblastic leukaemia (T-ALL) (2005) (11)
- Famotidine, a new H2-receptor antagonist, does not affect hepatic elimination of diazepam or tubular secretion of procainamide (2004) (10)
- Pharmacokinetic and pharmacodynamic interaction study of diazepam and metoprolol (2004) (10)
- Relationships between plasma levels and psychological effects of benzodiazepines. (1983) (10)
- Evidence for a cyclic nucleotide-phosphodiesterase with high specificity for cyclic uridine-3′,5′-monophosphate in rat adipose tissue (2005) (10)
- [Pharmacokinetic data for different 5-aminosalicylic acid and budesonide preparations]. (1999) (10)
- Clinical efficacy of oral 5-aminosalicylic acid in the treatment of inflammatory bowel disease. (1985) (10)
- A stable isotope method for the quantification of N-acetyl-5-aminosalicylic acid in plasma and urine. (1984) (10)
- PHYSICAL EXERCISE AND DISPOSITION OF DIAZEPAM (1978) (10)
- Steady state disposition of 5-aminosalicyclic acid following oral dosing. (1993) (10)
- Renal function was not impaired by treatment with 5-aminosalicylic acid in rats and man (1984) (9)
- Drug-induced hyponatraemia in elderly patients. (1999) (9)
- Concentration — effect relationships (1990) (9)
- Biliary excretion of H2-receptor antagonists (2007) (8)
- The Ibuprofen-Cimetidine Interaction (1989) (8)
- "Natural" benzodiazepines in man (1990) (8)
- Disposition of intravenous theophylline in asthmatic children: Bayesian approach vs direct pharmacokinetic calculations. (1997) (8)
- Radical-derived oxidation products of 5-aminosalicylic acid and N-acetyl-5-aminosalicylic acid. (1994) (8)
- Superoxide inhibition following different stimuli of respiratory burst and metabolism of aminosalicylates in neutrophils (2005) (8)
- [5-Aminosalicylic acid in ulcerative colitis and Crohn's disease (author's transl)]. (2008) (8)
- Impaired elimination of meperidine in patients with liver disease. (1974) (8)
- Effect of age on levels of diazepam in plasma and brain of rats (1979) (7)
- Acid secretion, response to omeprazole, and Helicobacter pylori status. (1997) (7)
- Age-related differences in the coordination disturbance and anticonvulsant effect of oxazepam in mice. (1989) (7)
- Pharmacokinetics of Epoetin (Recombinant Human Erythropoietin) after Long Term Therapy in Patients Undergoing Haemodialysis and Haemofiltration (1993) (7)
- Clearance of diazepam can be impaired by its major metabolite desmethyldiazepam (2004) (7)
- Determination of bromazepam by gas-liquid chromatography and its application for pharmacokinetic studies in man. (1981) (7)
- Effect of ranitidine on the steady state pharmacokinetics of diazepam (2004) (7)
- Pharmacokinetics of ranitidine in patients undergoing haemofiltration (2004) (7)
- Famotidine should be taken with supper : the effect of drug-meal interactions on gastric acidity and plasma famotidine levels (1991) (7)
- Relevance of deficient CYP2D6 in opiate dependence. (1998) (7)
- Age-Dependent Actions of Benzodiazepines (1986) (7)
- Variability in the frequency of cytochrome P450-2D6 (CYP2D6) deficiency. (1998) (7)
- Value, Limitations and Clinical Impact of Therapeutic Drug Monitoring in Adults (1993) (6)
- Food intake and plasma binding of diazepam. (1977) (6)
- Estimation of the blood-plasma concentration ratio of diazepam in the rat (1985) (6)
- Influence of cyclic guanosine-3′,5′-monophosphate on the enzymatic hydrolysis of adenosine-3′,5′-monophosphate (2004) (6)
- [Clinical pharmacokinetics of diazepam and its biologically active metabolites (author's transl)]. (1978) (6)
- Lorcainide infusion in the treatment of ventricular premature beats (VPB) (1979) (5)
- Rat adrenal cyclic nucleotide-phosphodiesterase; Inhibition by drugs known to affect steroidogenesis (2004) (5)
- Antipyrine metabolism is not affected by terbinafine, a new antifungal agent (2004) (5)
- Once-daily dosing of gentamicin: experience with therapeutic drug monitoring and Bayesian pharmacokinetics. (1994) (5)
- The pharmacokinetics and tissue distribution of the new antiarrhythmic agent lorcainide (R 15889) in rats. (1980) (5)
- Clinical Pharmacology of Benzodiazepines (1984) (5)
- Telomeres and telomerase as novel drug targets: reflections on the 2009 Nobel Prize in Physiology or Medicine (2009) (4)
- Stress protective effects during steady-state conditions of bromazepam. (1984) (4)
- [Significance of galenic preparations for luminal release of 5-aminosalicylic acid in human small intestinal lumen]. (1998) (4)
- Relationship between the venoconstrictor activity of dihydroergotamine and its pharmacokinetics during acute and chronic oral dosing (2004) (4)
- Reassessment of the benefit/risk-ratio of selective COX-2-inhibitors. (2005) (4)
- A method to assess histamine-induced cyclic AMP production in isolated gastric mucosal cells from human biopsies. (1991) (4)
- Proceedings: Pharmacokinetics and protein binding of diazepam in man and different species. (1975) (4)
- DISPOSITION AND CLINICAL EFFICACY OF METHOTREXATE IN PATIENTS WITH RHEUMATOID ARTHRITIS FOLLOWING WEEKLY, LOW, INTRAMUSCULAR DOSING: A PILOT STUDY (1997) (4)
- [Clinical pharmacology of midazolam]. (1989) (4)
- Gastric emptying in non-responders to H2-receptor antagonists (1990) (3)
- Abstract form for the Irish Journal of Medical Science v workshop on gastroduodenal pathology and Helicobacter pylori July 5th — 7th 1992 — Dublin, Ireland (1992) (3)
- Adenylate cyclase of gastric mucosa in patients with chronic renal failure. (1996) (3)
- Therapy of Inflammatory Bowel Disease using New 5-ASA Compounds: An Introduction (1989) (3)
- Performance of a New Automated Substrate‐Labeled Fluorescence Immunoassay System Evaluated by Comparative Therapeutic Monitoring of Five Drugs (1984) (3)
- Gastric emptying in patients with chronic renal failure. (1994) (3)
- Rat diaphragm cyclic nucleotide-phosphodiesterase: Influence of drugs affecting skeletal muscle contractility (2004) (3)
- [The effect of blood conservation techniques on the plasma concentration and elimination of midazolam in patients undergoing hip joint surgery]. (1992) (3)
- Comparison of theophylline blood levels measured by the standard TDx assay and a new patient-side immunoassay cartridge system. (1993) (3)
- Distribution of diazepam between plasma and whole blood. (2004) (3)
- [Effect of histamine H2-receptor antagonists on the hepatic elimination of drugs]. (1983) (3)
- Influence of liver disease on the elimination of drugs (1976) (3)
- Interlaboratory variability of valproic acid determinations. (1977) (2)
- CIMETDMNE (BUT NOT RANITIDINE OR FAMOTIDINE) AFFECTS HISTAMINE DETERMINATION (1988) (2)
- Analytical information is mandatory for pharmacokinetic papers (1996) (2)
- [5-aminosalicylic acid and chronic inflammatory bowel diseases in children]. (1995) (2)
- Pharmacokinetics and pharmacodynamics of famotidine in patients with reflux oesophagitis (2004) (2)
- [Recent therapeutic modalities in chronic inflammatory bowel diseases: 4- or 5-aminosalicylic acid?]. (1994) (2)
- Clinical pharmacology of mesalazine (5-aminosalicylic acid) in chronic inflammatory bowel disease (1989) (2)
- DETERMINANTS OF NON‐RESPONSE IN HELICOBACTER PYLORI ERADICATION TRIALS (2005) (2)
- Comparison of cyclosporine blood levels measured by radioimmunoassay and TDx assay using monoclonal antibodies. (1991) (2)
- Addition of misoprostol to ranitidine in non-responders to H2-blockers and pirenzepine. (1991) (1)
- Absence of antibodies stimulating H2-receptor mediated cyclic adenosine monophosphate (cAMP) production in peptic ulcer disease. (1992) (1)
- Omeprazole, amoxicillin and bismuth for peptic ulcer healing and Helicobacter pylori eradication. (1997) (1)
- Effects of berberine on the transport of P-gp substrates across Caco-2 and L-MDR1 cell monolayers (2007) (1)
- Altered Response to Benzodiazepines in the Elderly (1989) (1)
- [Drug interactions--their impact on safe drug therapy in the example of the new thiazolidinedione group (glitazone)]. (2001) (1)
- Proceedings: Hepatic elimination of diazepam and its active metabolites. (1976) (1)
- Introduction and definitions (1990) (1)
- [Peripheral benzodiazepine receptors and their possible biological role]. (1993) (1)
- Glucagon-induced alterations of plasma levels of cyclic AMP and glucose in patients with liver disease. (1984) (1)
- Essential and Non-Essential Metals Metabolites with Antibiotic Activity Pharmacology of Benzodiazepines Interferon Gamma Research (2011) (1)
- CYP2C19 Polymorphism and proton pump inhibitors (PPI) in Helicobacter Pylori eradication therapy–A Metaanalysis (2004) (1)
- Telomeres and Telomerase in Pediatric Patients with T-Cell Acute Lymphoblastic Leukemia (T-ALL). (2004) (1)
- Pharmacokinetics of Furosemide in Patients with Chronic Renal Failure (1993) (1)
- Bioavailability of β-acetyldigoxin after single and repeated doses of tablets and solution (2004) (1)
- Pharmacokinetics and pharmacodynamics of roxatidine in patients with renal insufficiency. (1995) (1)
- Combined effect of pirenzepine and ranitidine on the nocturnal intragastric pH in non-responders to ranitidine. (1990) (1)
- Cyclic nucleotide phosphodiesterases of human and rat gastric mucosa (2004) (1)
- Helicobacter pylori infection in dialyzed patients: bismuth therapy and pharmacokinetics. (1992) (1)
- The bridging function of clinical pharmacology (2007) (1)
- Pharmacokinetics of midazolam—a reply. (1987) (1)
- H2‐receptor blocking agents and hepatic drug elimination (1987) (1)
- [Effect of meals on resorption of bismuth from an oral bismuth gallate/bismuth nitrate preparation]. (1991) (1)
- New short-term ouadruple therapies for eradication of Helicobacter pylori (H. Pylori): Maclor study (1998) (1)
- Inadequate response to H2-receptor antagonists (1995) (1)
- Proceedings: The primary process of vascular smooth muscle contraction and the influence of stress, temperature, Ca++, H+, and norepinephrine. (1976) (1)
- Effect of intravenous ketanserin on plasma catecholamines and renin activity in normal volunteers (2004) (1)
- Clinical impact of mesalazine for research and therapy in inflammatory bowel diseases (2005) (0)
- 2510 – DISPOSITION AND ANTIARRHYTHMIC EFFECTS OF LORCAINIDE IN PATIENTS WITH VENTRICULAR PREMATURE BEATS (VPB) (1978) (0)
- Famotidine Properties and Suppression of Acid Secretion in Paediatric Patients Following Cardiac Surgery (1990) (0)
- Impact of genotypic differences in CYP2C19 status on the eradication of Helicobacter pylori in Caucasian patients (2003) (0)
- [Isoenzymes of the cytochrome P450 system: an accident or a physiologically significant concept?]. (1996) (0)
- Effect of Single Doses of Cimetidine and Ranitidine on the Steady-State Plasma Levels of Midazolam (1986) (0)
- Features of drugs used in inflammatory bowel disease: 5-aminosalicylic acid (mesalazine) (2008) (0)
- Telomeres and biological aging in man (1997) (0)
- SYNTHESES OF SOME N-SULFONYLIMINO AND N-ACYLIMINOTHIOCARBONIC ACID ALKYL ESTER CHLORIDES AND THEIR DERIVATIVES (1985) (0)
- Pharmacokinetics anddynamics offamotidine inpatients withrenal failure (1988) (0)
- SYNTHESES OF SUBSTITUTED ELECTRON‐RICH N‐SULFONYL‐1‐AZABUTADIENES (1985) (0)
- Hplc-Determination of Sulfapyridine and its Metabolites in Human Plasma and its Pharmacokinetics in Man (1978) (0)
- Liver function tests and elimination of drugs in man (1980) (0)
- Oral paper abstracts (2022) (0)
- Drug-related risks (2007) (0)
- Reply to S. Padol et al. (2007) (0)
- H2-Receptor antagonist nonresponders and omeprazole (1992) (0)
- [Clinical pharmacology and therapeutic uses of the specific benzodiazepine antagonist flumazenil]. (1989) (0)
- [Important factors determining human distribution and elimination of diazepam]. (1977) (0)
- A method to simultaneously investigate histamine-induced cyclic AMP and aminopyrine accumulation in isolated gastric mucosal cells from human biopsies. (1992) (0)
- [The interaction potential of H2 receptor antagonists. A short current review]. (1991) (0)
- In vitro study on histamine-induced cyclic adenosine monophosphate production in ulcer patients with different antisecretory responses to ranitidine. (1993) (0)
- 5-Aminosalicylic acid for the treatment of inflammatory bowel disease (1984) (0)
- Analytical performance of a mechanized substrate-labelled fluorescent immunoassay system evaluated by therapeutic drug monitoring (1984) (0)
- [Presystemic elimination and biological availability of drugs]. (1981) (0)
- The bioavailability of alpha-acetyldigoxin from Card-Hydergin--a fixed combination of Hydergine and acetyldigoxin. (1978) (0)
- Pharmacological Development of Aminosalicylates for the Treatment of Inflammatory Bowel Disease (2001) (0)
- [Pharmacology of proton pump inhibitors]. (2005) (0)
- [Plasma levels of anticonvulsants. Experiences with routine plasma level determination of 6 different anticonvulsants]. (1978) (0)
- [Successful acute treatment of chronic inflammatory intestinal diseases with oral 5-aminosalicylic acid]. (1985) (0)
- [Individualization of drug dosage by therapeutic monitoring in plasma and the application of pharmacokinetic principles]. (1983) (0)
- Recommended pharmacokinetic symbols, definitions and dimensions (1990) (0)
- Subject Index, Vol. 42, 1991 (1991) (0)
- Antiarrhythmics (2021) (0)
- Enzyme Inhibition and Induction-PK / PD Impact (2009) (0)
- Elevation of steady-state diazepam levels by cimetidine (1982) (0)
- Peptic Ulcer (PU) Healing and Helicobacter Pylori (Hp) Eradication (1996) (0)
- SYNTHESES OF DONOR-ACCEPTOR SUBSTITUTED N-(SULFONYLIMINO)RADIALENES (1985) (0)
- Proceedings: Pharmacokinetics of diazepam in man. (1974) (0)
- Alterstraumatologie I Proximaler Femur I (2000) (0)
- Biliary Excretion of β-Acetyl-Digoxin in Man (1978) (0)
- Rehabilitation nach Trauma (1999) (0)
- [Effects and side effects of benzodiazepines]. (1988) (0)
- SUBSTITUTION REACTIONS OF 3,7-DIALKOXY-4H,8H-BENZO(1,2-C:4,5-C′)DIISOXAZOLE-4,8-DIONES AND THEIR DERIVATIVES - SYNTHETIC STUDIES WITH ELECTRON-RICH OLEFINS AND OTHER NUCLEOPHILES (1985) (0)
- 120 – INFLUENCE OF DOSING AND LIVER DISEASE ON THE PHARMACOKINETICS OF DIAZEPAM IN MAN (1977) (0)
- Population Pharmacokinetics As A Tool To Re-Evaluate The Complex Disposition of Ethanol In The Fed And Fasted State. (2023) (0)
- ScienceDirect - Journal of Chromatography B, Volume 831, Issues 1-2, Pages 1-346 (2 February 2006) (2006) (0)
- Proceedings: Induction of drug metabolizing enzymes in man. (1976) (0)
- [Do benzodiazepines represent "natural" drugs?]. (1989) (0)
- Tables with pharmacokinetic data (1990) (0)
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