Ulf T. Brunk
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Ulf T. Brunkbiology Degrees
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Cell Biology
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Biology
Ulf T. Brunk's Degrees
- PhD Molecular Biology Stanford University
- Bachelors Biochemistry University of California, Berkeley
Why Is Ulf T. Brunk Influential?
(Suggest an Edit or Addition)Ulf T. Brunk's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Guidelines for the use and interpretation of assays for monitoring autophagy (2012) (6925)
- Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes (2008) (2360)
- Lipofuscin: mechanisms of age-related accumulation and influence on cell function. (2002) (837)
- Autophagy and Aging: The Importance of Maintaining "Clean" Cells (2005) (770)
- The mitochondrial-lysosomal axis theory of aging: accumulation of damaged mitochondria as a result of imperfect autophagocytosis. (2002) (724)
- Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features (2010) (508)
- Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species. (1993) (499)
- Mitochondrial turnover and aging of long-lived postmitotic cells: the mitochondrial-lysosomal axis theory of aging. (2010) (448)
- Sphingosine-induced apoptosis is dependent on lysosomal proteases. (2001) (375)
- Lipofuscin: Mechanisms of formation and increase with age (1998) (337)
- Oxidative stress, accumulation of biological 'garbage', and aging. (2006) (333)
- Lysosomal enzymes promote mitochondrial oxidant production, cytochrome c release and apoptosis. (2003) (295)
- Photo-oxidative disruption of lysosomal membranes causes apoptosis of cultured human fibroblasts. (1997) (286)
- Lysosomes in iron metabolism, ageing and apoptosis (2008) (263)
- A novel hypothesis of lipofuscinogenesis and cellular aging based on interactions between oxidative stress and autophagocytosis. (1992) (261)
- Lysosomes and oxidative stress in aging and apoptosis. (2008) (255)
- What does the commonly used DCF test for oxidative stress really show? (2010) (250)
- Autophagy in cardiac myocyte homeostasis, aging, and pathology. (2005) (247)
- Cellular injury induced by oxidative stress is mediated through lysosomal damage. (1995) (245)
- Induction of cell death by the lysosomotropic detergent MSDH (2000) (239)
- Antitumor activity of metal-chelating compound Dp44mT is mediated by formation of a redox-active copper complex that accumulates in lysosomes. (2011) (232)
- Lysosomal destabilization in p53-induced apoptosis (2002) (220)
- Intralysosomal iron: a major determinant of oxidant-induced cell death. (2003) (211)
- Induction of lysosomal membrane permeabilization by compounds that activate p53-independent apoptosis. (2005) (210)
- Autophagy, ageing and apoptosis: the role of oxidative stress and lysosomal iron. (2007) (199)
- The lysosomal-mitochondrial axis theory of postmitotic aging and cell death. (2006) (197)
- Apoptosis induced by exposure to a low steady-state concentration of H2O2 is a consequence of lysosomal rupture. (2001) (195)
- Vitamin E succinate is a potent novel antineoplastic agent with high selectivity and cooperativity with tumor necrosis factor-related apoptosis-inducing ligand (Apo2 ligand) in vivo. (2002) (185)
- Hydrogen peroxide production by liver mitochondria in different species (1990) (184)
- Prevention of oxidant-induced cell death by lysosomotropic iron chelators. (2003) (183)
- Oxidative stress, growth factor starvation and Fas activation may all cause apoptosis through lysosomal leak. (1999) (180)
- Relationship between antioxidant defenses and longevity in different mammalian species (1990) (178)
- PHOTOOXIDATIVE DAMAGE TO LYSOSOMES OF CULTURED MACROPHAGES BY ACRIDINE ORANGE (1990) (170)
- The role of lysosomes in iron metabolism and recycling. (2011) (165)
- Superoxide anion radical production in different animal species (1989) (162)
- Influence of epidermal growth factor (EGF) on ruffling activity, pinocytosis and proliferation of cultivated human glia cells. (1976) (158)
- Intralysosomal iron chelation protects against oxidative stress‐induced cellular damage (2006) (148)
- Demonstration of an extracellular matrix in multicellular tumor spheroids. (1984) (147)
- The comparative biology of neuromelanin and lipofuscin in the human brain (2008) (147)
- Lysosomal involvement in apoptosis (2001) (144)
- Mitochondrial recycling and aging of cardiac myocytes: the role of autophagocytosis (2003) (143)
- Lysosomal destabilization during macrophage damage induced by cholesterol oxidation products. (1999) (141)
- Electron microscopical studies on rat brain neurons. Localization of acid phosphatase and mode of formation of lipofuscin bodies. (1972) (137)
- The osmotic effect of glutaraldehyde during fixation. A transmission electron microscopy, scanning electron microscopy and cytochemical study. (1976) (135)
- Ceroid/lipofuscin formation in cultured human fibroblasts: the role of oxidative stress and lysosomal proteolysis (1998) (133)
- Apoptosis induced by exposure to a low steady-state concentration of H2O2 is a consequence of lysosomal rupture (2001) (132)
- Mitochondrial production of pro-oxidants and cellular senescence. (1992) (132)
- Aging of Cardiac Myocytes in Culture: Oxidative Stress, Lipofuscin Accumulation, and Mitochondrial Turnover (2004) (129)
- Lysosomal labilization (2006) (127)
- Metallothionein protects against oxidative stress-induced lysosomal destabilization. (2006) (124)
- Oxidized proteins: Mechanisms of removal and consequences of accumulation (2009) (123)
- HISTOCHEMICAL INDICATIONS FOR LYSOSOMAL LOCALIZATION OF HEAVY METALS IN NORMAL RAT BRAIN AND LIVER (1970) (123)
- Suppression of Tumor Growth In vivo by the Mitocan α-tocopheryl Succinate Requires Respiratory Complex II (2009) (122)
- Lipofuscin accumulation in cultured retinal pigment epithelial cells causes enhanced sensitivity to blue light irradiation. (1997) (118)
- Exposure of cells to nonlethal concentrations of hydrogen peroxide induces degeneration-repair mechanisms involving lysosomal destabilization. (1995) (117)
- H2O2-mediated damage to lysosomal membranes of J-774 cells. (1993) (117)
- Uptake of oxidized LDL by macrophages results in partial lysosomal enzyme inactivation and relocation. (1998) (117)
- Alpha-tocopheryl succinate, an agent with in vivo anti-tumour activity, induces apoptosis by causing lysosomal instability. (2002) (116)
- Aging as a catabolic malfunction. (2004) (115)
- Iron in human atheroma and LDL oxidation by macrophages following erythrophagocytosis. (1996) (112)
- Does the calcein-AM method assay the total cellular 'labile iron pool' or only a fraction of it? (2007) (111)
- Aging of cultured retinal pigment epithelial cells: oxidative reactions, lipofuscin formation and blue light damage (2004) (110)
- Mitochondrial damage and intralysosomal degradation in cellular aging. (2006) (109)
- Role of compartmentalized redox-active iron in hydrogen peroxide-induced DNA damage and apoptosis. (2005) (106)
- Redox activity within the lysosomal compartment: implications for aging and apoptosis. (2010) (104)
- Ceroid/lipofuscin-loaded human fibroblasts show decreased survival time and diminished autophagocytosis during amino acid starvation☆ (1999) (102)
- Specialization of cell surfaces in contact-inhibited human glia-like cells in vitro. (1971) (101)
- Lipofuscin accumulation in cultured retinal pigment epithelial cells reduces their phagocytic capacity. (1998) (99)
- Activation of the p38 MAP kinase pathway is required for foam cell formation from macrophages exposed to oxidized LDL (2002) (97)
- Phthalate Esters and Their Effect on the Liver (1984) (96)
- Relocalized redox-active lysosomal iron is an important mediator of oxidative-stress-induced DNA damage. (2004) (96)
- Endosomal and lysosomal effects of desferrioxamine: protection of HeLa cells from hydrogen peroxide-induced DNA damage and induction of cell-cycle arrest. (2003) (94)
- Protection against oxidant‐mediated lysosomal rupture: a new anti‐apoptotic activity of Bcl‐2? (2000) (94)
- Residual bodies and "aging" in cultured human glia cells. Effect of entrance into phase 3 and prolonged periods of confluence. (1973) (93)
- Lysosomal involvement in apoptosis. (1998) (90)
- Myocyte aging and mitochondrial turnover (2004) (89)
- Effect of ambient oxygen concentration on lipofuscin accumulation in cultured rat heart myocytes--a novel in vitro model of lipofuscinogenesis. (1989) (88)
- Lethal hydrogen peroxide toxicity involves lysosomal iron-catalyzed reactions with membrane damage. (1995) (86)
- Ceroid/Lipofuscin-loaded human fibroblasts show increased susceptibility to oxidative stress (1999) (85)
- Lipofuscin accumulation and ageing of fibroblasts. (1995) (82)
- The aging myocardium: roles of mitochondrial damage and lysosomal degradation. (2005) (82)
- Radiation-induced cell death: importance of lysosomal destabilization. (2005) (80)
- On the degradability and exocytosis of ceroid/lipofuscin in cultured rat cardiac myocytes (1998) (76)
- Endogenous ferritin protects cells with iron-laden lysosomes against oxidative stress. (1998) (75)
- Peroxisomal Impairment in Niemann-Pick Type C Disease* (1997) (75)
- Effects of iron- and hemoglobin-loaded human monocyte-derived macrophages on oxidation and uptake of LDL. (1995) (75)
- Fenton chemistry and iron chelation under physiologically relevant conditions: Electrochemistry and kinetics. (2006) (75)
- Sphingosine mediates TNFα-induced lysosomal membrane permeabilization and ensuing programmed cell death in hepatoma cells (2012) (71)
- Testing the “garbage” accumulation theory of ageing: mitotic activity protects cells from death induced by inhibition of autophagy (2004) (69)
- Cell sensitivity to oxidative stress is influenced by ferritin autophagy. (2011) (68)
- The toxicity to macrophages of oxidized low-density lipoprotein is mediated through lysosomal damage. (1997) (67)
- Lysosomal heterogeneity between and within cells with respect to resistance against oxidative stress (1997) (67)
- OxLDL-induced macrophage cytotoxicity is mediated by lysosomal rupture and modified by intralysosomal redox-active iron. (1998) (66)
- Visualization of iron in cultured macrophages: a cytochemical light and electron microscopic study using autometallography. (1993) (65)
- Involvement of heat shock protein-70 in the mechanism of hydrogen peroxide-induced DNA damage: the role of lysosomes and iron. (2007) (65)
- Lipofuscin as an indicator of oxidative stress and aging. (1989) (62)
- A comparison of the effects of three widely used glutaraldehyde fixatives on cellular volume and structure. A TEM, SEM, Volumetric and Cytochemical Study. (2009) (61)
- 3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin. (2003) (61)
- ARPE-19 retinal pigment epitheliaL CELLS are highly resistant to oxidative stress and exercise strict control over their lysosomal redox-active iron (2009) (60)
- Influence of oxygen tension, pro-oxidants and antioxidants on the formation of lipid peroxidation products (lipofuscin) in individual cultivated human glial cells (1984) (59)
- Lipofuscin-formation in cultured retinal pigment epithelial cells is related to their melanin content. (2001) (59)
- DNA content, malignancy grading and prognosis in T1 and T2 oral cavity carcinomas. (1987) (59)
- Accumulation of lipofuscin within retinal pigment epithelial cells results in enhanced sensitivity to photo-oxidation. (1995) (57)
- Histochemical demonstration of heavy metals with the sulfide-silver method. A methodological study. (1968) (56)
- Cytocidal effects of atheromatous plaque components: the death zone revisited (2006) (55)
- The Involvement of Lysosomes in Myocardial Aging and Disease (2008) (55)
- Novel cellular defenses against iron and oxidation: ferritin and autophagocytosis preserve lysosomal stability in airway epithelium (2001) (52)
- Vitamin E analogs: A new class of multiple action agents with anti-neoplastic and anti-atherogenic activity (2002) (52)
- Polydatin, a natural polyphenol, protects arterial smooth muscle cells against mitochondrial dysfunction and lysosomal destabilization following hemorrhagic shock. (2012) (50)
- On the cytoprotective role of ferritin in macrophages and its ability to enhance lysosomal stability. (1997) (49)
- The demonstration of acid phosphatase inin vitro cultured tissue cells. Studies on the significance of fixation, tonicity and permeability (1972) (49)
- Iron and LDL‐oxidation in atherogenesis. (1998) (46)
- Effect of ferric iron and desferrioxamine on lipofuscin accumulation in cultured rat heart myocytes (1988) (46)
- Cytofluorometric quantitation of acridine orange uptake by cultured cells. (2009) (44)
- Autophagy of HSP70 and chelation of lysosomal iron in a non-redox-active form (2009) (44)
- Induction of fibroblast apolipoprotein E expression during apoptosis, starvation-induced growth arrest and mitosis. (2004) (43)
- Formation of lipofuscin in cultured retinal pigment epithelial cells exposed to pre‐oxidized photoreceptor outer segments (1996) (42)
- Isolation of peroxisomes from rat liver using sucrose and Percoll gradients. (1981) (41)
- Cytochemical evidence for the leakage of acid phosphatase through ultrastructurally intact lysosomal membranes (1972) (41)
- Squamous cell carcinoma of the oral cavity. A review of 176 cases with application of malignancy grading and DNA measurements. (1990) (41)
- Oxidant-induced apoptosis: a consequence of lethal lysosomal leak? (1997) (38)
- Foam cell death induced by 7beta-hydroxycholesterol is mediated by labile iron-driven oxidative injury: mechanisms underlying induction of ferritin in human atheroma. (2005) (38)
- Chelation of lysosomal iron protects against ionizing radiation. (2010) (38)
- Mechanisms of lipofuscinogenesis: Effect of the inhibition of lysosomal proteinases and lipases under varying concentrations of ambient oxygen in cultured rat neonatal myocardial cells (1991) (37)
- The potential intermediate role of lysosomes in oxygen free radical pathology (1988) (36)
- Relationship between the endoplasmic reticulum-Golgi membrane system and ubiquinone biosynthesis. (1995) (36)
- Distribution and shifts of ingested marker particles in residual bodies and other lysosomes. Studies on in vitro cultivated human glia cells in phase II and 3. (1973) (36)
- Effect of iron on the stability of macrophage lysosomes (1983) (35)
- Congenital disorders sharing oxidative stress and cancer proneness as phenotypic hallmarks: prospects for joint research in pharmacology. (1998) (33)
- Autophagy of metallothioneins prevents TNF-induced oxidative stress and toxicity in hepatoma cells (2015) (32)
- An experimental model system for leishmaniasis (1988) (32)
- Characterization of residual bodies formed in phase II cultivated human glia cells (1976) (31)
- Phagocytosis and degradation of rat liver mitochondria by cultivated human glial cells. (1980) (31)
- Human neuroblastoma (SH-SY5Y) cells are highly sensitive to the lysosomotropic aldehyde 3-aminopropanal (2004) (31)
- Effects of dietary di(2-ethylhexyl)phthalate on the structure and function of rat hepatocytes. (1983) (31)
- Fenton reagents may not initiate lipid peroxidation in an emulsified linoleic acid model system. (1992) (30)
- Acridine orange-mediated photodamage of microsomal- and lysosomal fractions (1988) (29)
- Quantitation of residual bodies in cultured human glial cells during stationary and logarithmic growth phases (1978) (28)
- The fine structure of three-dimensional colonies of human glioma cells in agarose culture. (2009) (28)
- Microfluorometric and fluorometric lipofuscin spectral discrepancies: A concentration-dependent metachromatic effect? (1991) (27)
- Evaluation of lysosomal stability in living cultured macrophages by cytofluorometry (1988) (27)
- A short exposure to a high‐glucose milieu stabilizes the acidic vacuolar apparatus of insulinoma cells in culture to ensuing oxidative stress (1997) (27)
- Effects of prolonged administration of phthalate ester on the liver. (1987) (26)
- Decreased apoptotic response of inclusion-cell disease fibroblasts: a consequence of lysosomal enzyme missorting? (2002) (26)
- Proteins containing oxidized amino acids induce apoptosis in human monocytes. (2011) (26)
- On the origin of lipofuscin; the iron content of residual bodies, and the relation of these organelles to the lysosomal vacuome. A study on cultured human glial cells. (1989) (25)
- An experimental model system for leishmaniasis. An ultrastructural study on cultured macrophages exposed to Leishmania parasites and sodium stibogluconate. (1988) (25)
- A Histological Study of the Effect on the Placenta of Intra‐Amniotically and Extra‐Amniotically Injected Hypertonic Saline in Therapeutic Abortion (1972) (24)
- Effects of prolonged treatment with phthalate ester on rat liver. (1990) (24)
- Influence of intracellular glutathione concentration of lipofuscin accumulation in cultured neonatal rat cardiac myocytes. (1994) (23)
- The oxidation problem in the sulphide-silver method for histochemical demonstration of metals. (1967) (23)
- Lysosomal Redox‐Active Iron Is Important for Oxidative Stress‐Induced DNA Damage (2004) (22)
- Autophagy of iron-binding proteins may contribute to the oxidative stress resistance of ARPE-19 cells. (2013) (21)
- Test-tube simulated lipofuscinogenesis. Effect of oxidative stress on autophagocytotic degradation (1995) (21)
- Beta-cells, oxidative stress, lysosomal stability, and apoptotic/necrotic cell death. (1999) (21)
- Alpha-lipoic acid and alpha-lipoamide prevent oxidant-induced lysosomal rupture and apoptosis. (2001) (21)
- CHAPTER VI – ALTERATIONS IN LYSOSOMAL MEMBRANES AS RELATED TO DISEASE PROCESSES (1975) (21)
- Redox availability of lens iron and copper: implications for HO* generation in cataract. (1999) (20)
- Heat shock proteins: keys to healthy ageing? (2009) (20)
- ULTRASTRUCTURAL FEATURES OF CULTURED HUMAN GLIA AND GLIOMA CELLS (1979) (20)
- Protective induction of Hsp70 in heat‐stressed primary myoblasts: Involvement of MAPKs (2013) (20)
- Effect of alpha-tocopherol and some metal chelators on lipofuscin accumulation in cultured neonatal rat cardiac myocytes. (1990) (20)
- The half-lives of dolichol and dolichyl phosphate in rat liver (1988) (20)
- Residual bodies and "aging" in cultured human glia cells. Effect of entrance into phase 3 and prolonged periods of confluence. (1973) (19)
- Flow cytofluorometry of lysosomal acridine orange uptake by living cultured cells. Effect of trypsinization and starvation. (2009) (18)
- Mustard seeds (Sinapis Alba Linn) attenuate azoxymethane-induced colon carcinogenesis (2011) (18)
- Advanced glycation end products induce actin rearrangement and subsequent hyperpermeability of endothelial cells THIS ARTICLE HAS BEEN RETRACTED (2006) (18)
- High resolution SEM of cultured cells: preparatory procedures. (1981) (18)
- Lability of human decidual cells. In vitro effects of autolysis and osmotic stress. (1973) (17)
- Fractionation of isolated liver cells after disruption with a nitrogen bomb and sonication. (1982) (17)
- The effect of aging on lysosomal permeability in nerve cells of the central nervous system. An enzyme histochemical study in rat (2004) (17)
- Changes in the Levels of Dolichol and Dolichyl Phosphate in a Murine Model of Niemann‐Pick's Type C Disease (1995) (16)
- Macrophage erythrophagocytosis and iron exocytosis. (1996) (16)
- Cytoplasmic Effects of X‐Irradiation on Cultured Cells in a Nondividing Stage (1978) (16)
- Influence of cyclosporin A treatment on intracellular membranes of hepatocytes. (1986) (16)
- Heavy metal localization and age related accumulation in the rat nervous system (1973) (16)
- Cytoplasmic effects of X-irradiation on cultured cells 2. Alterations in lysosomes, plasma membrane, Golgi apparatus, and related structures. (1977) (15)
- Ultrastructural alterations in macrophages after phagocytosis of acrylic microspheres. (1984) (15)
- Histochemical studies on brain phosphatases in experimental lead poisoning. (2009) (15)
- Establishment of attached and non‐attached cell lines from an uncommon human glioma (1981) (14)
- Is aging the price for memory? (2005) (14)
- Effects of clofibrate administration to rats on their hepatocytes. (1980) (14)
- Roles of Mitogen-Activated Protein Kinases in the Modulation of Endothelial Cell Function Following Thermal Injury (2011) (14)
- Heterogeneous expression of apolipoprotein‐E by human macrophages (2004) (14)
- Starvation-induced autophagocytosis enhances the susceptibility of insulinoma cells to oxidative stress. (1996) (14)
- Oxidized ascorbic acid and reaction products between ascorbic and amino acids might constitute part of age pigments (1991) (14)
- Acrylic microspheres in vivo VII: morphological studies on mice and cultured macrophages. (1983) (13)
- Prognostic value of malignancy grading and DNA measurements in small glottic carcinomas. (1987) (13)
- THE FINE STRUCTURE OF GROWING HUMAN GLIA AND GLIOMA CELLS Whole Cell Preparations (1979) (13)
- Dimethylsulfoxide increases the survival and lysosomal stability of mouse peritoneal macrophages exposed to low-LET ionizing radiation and/or ionic iron in culture (1984) (13)
- Modulation of metabolism in HepG2 cells upon treatment with cyclosporin A and Nva2-cyclosporin. (1991) (12)
- Malignancy grading and cytophotometric evaluation of T1 lip carcinomas. (1987) (12)
- THE P38&agr; AND P38&dgr; MAP KINASES MAY BE GENE THERAPY TARGETS IN THE FUTURE TREATMENT OF SEVERE BURNS (2010) (12)
- Effect of ethanol on lipofuscin accumulation in cultured rat cardiac myocytes. (1989) (12)
- Dopa-responsive dystonia with depigmentation of the substantia nigra and formation of Lewy bodies (1992) (12)
- Starvation-induced autophagocytosis paradoxically decreases the susceptibility to oxidative stress of the extremely oxidative stress-sensitive NIT insulinoma cells. (1997) (12)
- Lipofuscinogenesis in a model system of cultured cardiac myocytes. (1992) (11)
- Age-related lysosomal dysfunction: an unrecognized roadblock for cobalamin trafficking? (2011) (11)
- Plasma Membrane Motility Of Cultured Human Glia Cells in Phase II and III (1978) (11)
- Cell motility and proliferation in relation to available substratum area, serum concentration and culture age. (1979) (11)
- One-electron transfer reactions of diquat radical to different reduction intermediates of oxygen. Formation of hydroxyl radical and electronically excited states. (1988) (11)
- Divergent pathways for TNF and C(2)-ceramide toxicity in HTC hepatoma cells. (2009) (10)
- Rivanol induced alterations of cultured cells. A fluorescence microscopic, scanning electron microscopic, and cytochemical study. (1977) (10)
- Dietary Mustard Seeds (Sinapis alba Linn) Suppress 1,2-Dimethylhydrazine-Induced Immuno-Imbalance and Colonic Carcinogenesis in Rats (2012) (10)
- An experimental model system for leishmaniasis. Effects of porphyrin-compounds and menadione on Leishmania parasites engulfed by cultured macrophages. (1988) (10)
- Lead induced injury of in vitro cultured rat fibroblasts. A light and electron microscopical study. (2009) (10)
- Distribution and shifts of ingested marker particles in residual bodies and other lysosomes. Studies on in vitro cultivated human glia cells in phase II and 3. (1973) (10)
- Plasma Membrane Motility and Proliferation of Human Glioma Cells In Agarose and Monolayer Cultures (1978) (10)
- Acute and irreversible injury following exposure of cultured cells to reactive oxygen metabolites. (1983) (10)
- Cytoplasmic effects of x-irradiation on cultured cells in a nondividing stage. 1. Establishment of an experimental model. (2009) (9)
- In vivo labelling of cytosomes for fine structural studies of auto- and hetero-phagocytosis. (1968) (9)
- Ear involvement in ligneous conjunctivitis: a rarity or an under-diagnosed condition? (2002) (9)
- THE FINE STRUCTURE OF “DIVIDERS” AND “NON‐DIVIDERS” IN PHASE II HUMAN GLIAL CELL CULTURES (1980) (8)
- Alloxan cytotoxicity is highly potentiated by plasma membrane- and lysosomal-associated iron — a study on a model system of cultured J-774 cells (1993) (8)
- Lability of Human Decidual Cells. IN Vivo Effects of Hypertonic Saline (1974) (8)
- Effect of phthalate ester metabolites on rat liver. (1982) (7)
- Lysosomotropic detergents induce time- and dose-dependent apoptosis/necrosis in cultured cells (2000) (7)
- Electron probe X-ray microanalysis of residual bodies in aged cultured human glial cells. (1980) (7)
- Biodegradable microspheres. VII: Alterations in mouse liver morphology after intravenous administration of polyacryl starch microparticles with different biodegradability. (1988) (7)
- Ascorbate and endocytosed Motexafin gadolinium induce lysosomal rupture. (2011) (7)
- Erratum: Mitochondrial turnover and aging of long-lived postmitotic cells: The mitochondrial-lysosomal axis theory of aging (Antioxidants & Redox Signaling (2009)) (2010) (7)
- Enzyme histochemical investigations of the inhibitory effect of zinc on the injurious action of carbon tetrachloride on the liver. (1967) (7)
- Histochemical evidence for lysosomal uptake of lead in tissue cultured fibroblasts (2004) (7)
- Cellular aspects of phototoxic reactions induced by kynurenic acid. I. Establishment of an experimental model utilizing in vitro cultivated cells. (1977) (6)
- GROWTH STIMULATION OF AGED CELLS IN CULTURE (1979) (6)
- Nonmembrane associated dolichol in rat liver (2006) (6)
- Cellular aspects of phototoxic reactions induced by kynurenic acid. II. Fine structural analysis and cytochemistry on cultivated cells. (1978) (6)
- Autofluorescent ceroid/lipofuscin. (1998) (6)
- Specimen preparation techniques (1982) (5)
- Lead induced injury on in vitro cultured rat fibroblasts (1973) (5)
- Intracellular interactions under oxidative stress and aging: a hypothesis. (1993) (5)
- TEM and SEM findings in cat fibroblasts cultivated in vitro with and without Mycoplasma. (2009) (5)
- CYTOPLASMIC EFFECTS OF X‐IRRADIATION ON CULTURED CELLS IN A NON‐DIVIDING STAGE (1980) (5)
- Lipofuscin accumulation in cultured non-dividing cells as a function of time and oxygen tension. (1986) (5)
- Advanced glycation end products induce actin rearrangement and subsequent hyperpermeability in endothelial cells (2006) (5)
- Is lipofuscin eliminated from cells? (1999) (4)
- Carbonyl Toxification Hypothesis of Biological Aging (2017) (4)
- Peroxide hormesis? A commentary on "Hydrogen peroxide inhibits caspase-dependent apoptosis by inactivating procaspase-9 in an iron-dependent manner". (2007) (4)
- Dye standards, Part I: terminology and general principles (1992) (4)
- Translocation of human glial and glioma cells in culture (1986) (4)
- Autophagy of iron-binding proteins may contribute to the oxidative stress resistance of ARPE-19 cells. (2013) (4)
- The Reaction between Oxymyoglobin and Hydroperoxides (1988) (4)
- The use of ultrasonic aspirator, Sonocut, for removal of brain tumours. Analysis of 26 consecutive cases. (1989) (4)
- Linköping University Postprint LYSOSOMES IN IRON METABOLISM , AGEING AND APOPTOSIS (2008) (4)
- An approach to the exploitation of scanning electron microscopy in studies of cultures of human cells (1980) (4)
- Effect of DTPA on histochemically demonstrable non-specific alkaline phosphatase. (1967) (4)
- An approach to the assessment of membrane stability of cultured cells. (1983) (3)
- The effect of Polbax extract on lipofuscin accumulation in cultured neonatal rat cardiac myocytes (2002) (3)
- Lysosomes and residual bodies in neurons and in vitro cultivated glia cells (1973) (3)
- The influence of cell co‐operation, nutrients and surface area on cell division (1993) (3)
- Phospholipid and enzyme arrangements of rat liver rough microsomal subfractions from control and methylcholanthrene-treated animals. (1982) (3)
- DYE STANDARDS .2.2. METHYL GREEN (CI 42585) AND ETHYL GREEN (CI-42590). (1992) (3)
- Motility pattern of density growth inhibited glial cells with partially free borders. (1979) (3)
- Scanning electron microscopy of acarus scabiei. (1975) (3)
- Mitochondria : Potential importance in hyperoxic lung injury (2000) (3)
- DYE STANDARDS .2.5. PARAROSANILINE (CI-42500). (1992) (3)
- Aging and Lysosomal Degradation of Cellular Constituents (2003) (3)
- DYE STANDARDS .2.6. ROSANILINE (CI-42510). (1992) (3)
- DYE STANDARDS .2.3. THIONIN (CI-52000). (1992) (3)
- DYE STANDARDS .2.7. MAGENTA-II (NO CI NUMBER). (1992) (2)
- SEM of the tubules of the hepatopancreas and the stomach gland of the scorpion (buthus quinquestriatus): A methodological study (1980) (2)
- DYE STANDARDS .2.4. VICTORIA BLUE-B (CI-44045). (1992) (2)
- Histochemical study of heavy metals in the rat brain at various ages. (1968) (2)
- Changes associated with the growth stimulation of in vitro cultivated spheroids of human glioma cells. (1981) (2)
- Mechanisms of lipofuscinogenesis: Effect of the inhibition of lysosomal proteases and lipases under varying concentrations of ambient oxygen in cultured rat neonatal myocardial cells (1990) (2)
- Effect of prolonged phthalate ester administration on rat liver. (1985) (2)
- Growing cells at 40% ambient oxygen conditions them to subsequent oxidative stress (2007) (2)
- Diabetic Peripheral Neuropathy: Possible Involvement of Iron Bound to Glycated Basement Membrane Proteins † 470 (1998) (2)
- DYE STANDARDS .2.1. PYRONIN-Y (CI-45005). (1992) (2)
- DYE STANDARDS .2.8. NEW FUCHSIN (CI-42520). (1992) (2)
- Oxidative Stress and Lysosomes (2011) (1)
- RESPIRATORY TRACT INFLAMMATION AFTER EXPOSURE TO FIRE SMOKE (2009) (1)
- Lysosomal leakage causes apoptosis following oxidative stress, growth-factor starvation and FAS-activation. (1999) (1)
- List of Key Words (1995) (1)
- Length of foetus and ossification of the toe and finger phalanges. (1962) (1)
- Lipofuscin accumulation in cultured retinal pigment epithelial cells is dependent on the melanin content (2000) (1)
- [Regular exposure to plasticizers can have a harmful effect on health]. (1984) (1)
- CYTOPLASMIC EFFECTS OF X-IRRADIATION ON CULTURED CELLS IN A NON-DIVIDING STAGE: 2. Alterations in Lysosomes, Plasma Membrane, Golgi Apparatus, and Related Structures (2009) (1)
- Lipofuscin, Lysosomes, and Iron (2018) (1)
- EFFECT OF MODE OF SACRIFICE ON HISTOCHEMICALLY DEMONSTRABLE ACTIVITY ON UNSPECIFIC ESTERASES AND UNSPECIFIC ALKALINE MONOPHOSPHATASES IN GOLDEN HAMSTERS. (1964) (1)
- Lysosomes, iron and oxidative stress (2003) (1)
- Influence of dolichol on microsomal membrane functions. (1996) (1)
- Cytoplasmic effects of X-irradiation on cultured cells in a non-dividing stage. 4. Studies of sparsely grown, serum-deprived cells. (1980) (0)
- Septic shock and the lysosomal-mitochondrial axis theory of apoptosis (2009) (0)
- Chelation of intralysosomal redox-active iron protects against ionizing radiation damage (2012) (0)
- The H2DCF-DA Technique Shows Mainly the Mitochondrial Oxidative Stress in ARPE-19 Cells (2009) (0)
- 61 Macrophage-lysosomal enzyme relocalization and inactivation by oxidized LDL and protective effects of antioxidants (1997) (0)
- An experimental model system for leishmaniasis (1988) (0)
- Relocation of lysosomal enzymes induces mitochondria-mediated oxidative stress, release of cytochrome c, and apoptosis (2012) (0)
- Lysosomal Pathways of Protein Degradation by J. Fred Dice; In: Molecular Biology Intelligence Unit 11, LANDES BIOSCIENCE and EUREKAH.COM, Georgetown and Austin, Texas, USA, 2000, 108 pages, ISBN 1-58706-003-5 (2001) (0)
- LYSOSOMAL MECHANISMS OF DEATH BY TNF IN HEPATOMA CELLS (2013) (0)
- Transmission and scanning electron microscopy of whole glioma cells cultured in vitro. (1980) (0)
- Lysosomotropic agents : a possible new class of site-directed anti-oxidant, anti-inflammatory and radioprotectant drugs (2002) (0)
- CALL FOR PAPERS Integrative and Translational Physiology: Integrative Aspects of Energy Homeostasis and Metabolic Diseases Polydatin, a natural polyphenol, protects arterial smooth muscle cells against mitochondrial dysfunction and lysosomal destabilization following hemorrhagic shock (2012) (0)
- Why are retinal pigment epithelial cells so resistant to oxidative stress? (2010) (0)
- PROGRAMMED, ACCIDENTAL AND SECONDARY NECROSIS CONVERGE ON SIMILAR CELLULAR DISINTEGRATION FEATURES in ADVANCES IN TNF FAMILY RESEARCH (2011) (0)
- 3.P.287 Ferritin accumulation in human atheroma and its relation to apoptosis (1997) (0)
- Ferritin protects aitway epithelium against iron and oxidation (2001) (0)
- Effects of iron- and hemoglobin-loaded human monocyte-derived macrophages (HMDM) on LDL oxidation and uptake (1994) (0)
- Visualization of heavy metals in cultured macrophages and hepatocytes. A cytochemical light and electron microscopical study using the silver enhancement technique (physical development) (1990) (0)
- Title Page / Table of Contents, Supplement 2, 1995 (1995) (0)
- Jun protein expression is required for serum induced smooth muscle cells proliferation - Regulated by p38 and BMK1 map kinases cooperatively (2000) (0)
- THE P38 ! AND P38 % MAP KINASES MAY BE GENE THERAPY TARGETS IN THE FUTURE TREATMENT OF SEVERE BURNS (2018) (0)
- Fighting fire with fire: Lysosomal targeting overcomes resistance (2018) (0)
- Growth and morphological characteristics of two brain metastases of human large cell carcinomas of the lung in vivo and in monolayer and spheroid cultures. (1982) (0)
- Disorders of peripheral nerves By Herbert H. Schaumburg, Alan R. Berger, and P.K. Thomas F.A. Davis Company, Philadelphia (1991) 348 pages, illustrated, $70.00 ISBN: 8036-7734-0 (1992) (0)
- INDUCTION OF MITOCHONDRIA AND PEROXISOMES WITH PHTHALATE ESTERS (1981) (0)
- In vitro differentiation and specialization of cell surfaces in human glia-like cells. (1971) (0)
- A lysosomotropic form of alpha-lipoic acid : a possible therapy of diabetic complications? (2002) (0)
- Fine structural studies on cultured human glial and glioma cells: techniques and applications. (1984) (0)
- Tu-W18:7 Isolation and cytocidal effects of ceroid and lipidaceous gruel from atheromatous plaque (2006) (0)
- Cellular aging and cell death by N.J. Holbrook, G.R. Martin, and R.A. Lockshin (eds.) in the modern cell biology series, vol. 16, Wiley-Liss Inc., New York, NY, 1996, 30 pages, ISBN 0-471-12123-1, $89.95 (1996) (0)
- H2DCF Oxidation Seems to be Dependent on Free Iron and Cytochrome C as Studied in ARPE-19 Cells (2010) (0)
- Book review "Lysosomal pathways of protein degradation" (2001) (0)
- Involvement of lysosomal enzymes and CPP 32-like protease in macrophage apoptosis induced by 7-ketocholesterol and 7beta;-hydroxycholesterol (1999) (0)
- Abstract B245: The antitumor agent, Dp44mT, perturbs lysosomal function by binding copper and inducing oxidative damage (2009) (0)
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