Ülo Langel
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Estonian biochemist
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Ülo Langelbiology Degrees
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Biochemistry
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Biology
Ülo Langel's Degrees
- PhD Biochemistry University of Tartu
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(Suggest an Edit or Addition)Ülo Langel's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Mechanisms of Cellular Uptake of Cell-Penetrating Peptides (2011) (818)
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 (2021) (811)
- Cell-penetrating peptides: design, synthesis, and applications. (2014) (701)
- Cell penetration by transportan. (1998) (636)
- Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo (1998) (538)
- Cell-Penetrating Peptides (2000) (418)
- Delivery of short interfering RNA using endosomolytic cell‐penetrating peptides (2007) (314)
- Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo (2011) (282)
- A brief introduction to cell‐penetrating peptides (2003) (216)
- PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation (2011) (210)
- Receptor–receptor interactions within receptor mosaics. Impact on neuropsychopharmacology (2008) (195)
- Cellular translocation of proteins by transportan (2000) (181)
- Cell-Penetrating Peptides : Processes and Applications (2002) (171)
- Handbook of cell-penetrating peptides (2006) (152)
- Scavenger receptor‐mediated uptake of cell‐penetrating peptide nanocomplexes with oligonucleotides (2012) (143)
- Induction of splice correction by cell‐penetrating peptide nucleic acids (2006) (141)
- Cell entry and antimicrobial properties of eukaryotic cell‐ penetrating peptides (2004) (140)
- In vitro Uptake and Stability Study of pVEC and Its All-D Analog (2003) (136)
- A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors (2018) (133)
- Cell-penetrating peptides for the delivery of nucleic acids (2012) (131)
- In vivo biodistribution and efficacy of peptide mediated delivery. (2010) (128)
- Anticonvulsant activity of a nonpeptide galanin receptor agonist (2002) (127)
- Design of a Tumor-Homing Cell-Penetrating Peptide (2008) (125)
- A Novel Cell-penetrating Peptide, M918, for Efficient Delivery of Proteins and Peptide Nucleic Acids. (2007) (124)
- Galanin type 2 receptors regulate neuronal survival, susceptibility to seizures and seizure‐induced neurogenesis in the dentate gyrus (2004) (121)
- Galanin Receptors and Ligands (2012) (119)
- Intramembrane receptor–receptor interactions: a novel principle in molecular medicine (2006) (113)
- Applications of Cell-Penetrating Peptides for Tumor Targeting and Future Cancer Therapies (2012) (113)
- Sensitive and rapid detection of Chlamydia trachomatis by recombinase polymerase amplification directly from urine samples. (2014) (113)
- Evidence for a role of the neuropeptide galanin in spatial learning (1992) (112)
- Secondary structure and position of the cell-penetrating peptide transportan in SDS micelles as determined by NMR. (2001) (107)
- Galanin and its receptors in neurological disorders (2007) (105)
- Differential Role of Galanin Receptors in the Regulation of Depression-Like Behavior and Monoamine/Stress-Related Genes at the Cell Body Level (2008) (102)
- Penetration without cells: membrane translocation of cell-penetrating peptides in the model giant plasma membrane vesicles. (2011) (100)
- Recent in vivo advances in cell-penetrating peptide-assisted drug delivery (2016) (99)
- PEG shielded MMP sensitive CPPs for efficient and tumor specific gene delivery in vivo. (2015) (98)
- Knockdown of L Calcium Channel Subtypes: Differential Effects in Neuropathic Pain (2010) (98)
- Galanin receptor subtypes and ligand binding (2000) (95)
- Characterization of a Novel Cytotoxic Cell-penetrating Peptide Derived From p14ARF Protein. (2008) (93)
- Prediction of Cell-Penetrating Peptides (2005) (92)
- Novel cell‐penetrating peptide targeting mitochondria (2015) (90)
- Evidence for endogenous inhibition of autotomy by galanin in the rat after sciatic nerve section: demonstrated by chronic intrathecal infusion of a high affinity galanin receptor antagonist (1993) (89)
- PepFect14 peptide vector for efficient gene delivery in cell cultures. (2013) (88)
- The neuropeptide galanin modulates behavioral and neurochemical signs of opiate withdrawal (2003) (85)
- Different domains in the third intracellular loop of the GLP-1 receptor are responsible for Gαs and Gαi/Gαo activation (2001) (81)
- Differential membrane perturbation caused by the cell penetrating peptide Tp10 depending on attached cargo (2007) (79)
- Studying the uptake of cell-penetrating peptides (2006) (71)
- Cell-penetrating peptides with intracellular organelle targeting (2017) (71)
- A galanin-mastoparan chimeric peptide activates the Na+,K+-ATPase and reverses its inhibition by ouabain (1996) (69)
- Graphene oxide nanosheets in complex with cell penetrating peptides for oligonucleotides delivery. (2017) (68)
- Gene delivery using cell penetrating peptides-zeolitic imidazolate frameworks (2020) (67)
- Chemically modified cell-penetrating peptides for the delivery of nucleic acids (2009) (66)
- Magnetic Nanoparticle Assisted Self-assembly of Cell Penetrating Peptides-Oligonucleotides Complexes for Gene Delivery (2017) (65)
- NickFects, Phosphorylated Derivatives of Transportan 10 for Cellular Delivery of Oligonucleotides (2011) (64)
- Translocation of cell-penetrating peptides across the plasma membrane is controlled by cholesterol and microenvironment created by membranous proteins. (2014) (62)
- Design of a Tumor Homing Cell-Penetrating Peptide for Drug Delivery (2009) (57)
- Carbonized chitosan encapsulated hierarchical porous zeolitic imidazolate frameworks nanoparticles for gene delivery (2020) (57)
- Chitosan enhances gene delivery of oligonucleotide complexes with magnetic nanoparticles–cell-penetrating peptide (2018) (57)
- A Galanin Receptor Subtype 1 Specific Agonist (2005) (56)
- Solid formulation of cell-penetrating peptide nanocomplexes with siRNA and their stability in simulated gastric conditions (2012) (54)
- Uptake Mechanism of Cell-Penetrating Peptides. (2017) (54)
- Book Review: Galanin: An Endogenous Anticonvulsant? (2001) (54)
- Apolar surface area determines the efficiency of translocon-mediated membrane-protein integration into the endoplasmic reticulum (2011) (54)
- Cellular delivery of a double-stranded oligonucleotide NFκB decoy by hybridization to complementary PNA linked to a cell-penetrating peptide (2004) (52)
- Organellar oligopeptidase (OOP) provides a complementary pathway for targeting peptide degradation in mitochondria and chloroplasts (2013) (52)
- Classes of Cell-Penetrating Peptides. (2015) (51)
- Assessing the delivery efficacy and internalization route of cell-penetrating peptides (2007) (49)
- Galanin—A neuropeptide with inhibitory actions (1995) (49)
- Different role of intracellular loops of glucagon-like peptide-1 receptor in G-protein coupling (2003) (48)
- M871—A Novel Peptide Antagonist Selectively Recognizing the Galanin Receptor Type 2 (2006) (48)
- Killer Bee Molecules: Antimicrobial Peptides as Effector Molecules to Target Sporogonic Stages of Plasmodium (2013) (47)
- A novel GalR2-specific peptide agonist (2009) (46)
- Binding and agonist/antagonist actions of M35, galanin(1-13)-bradykinin(2-9) amide chimeric peptide, in Rin m 5F insulinoma cells (1995) (45)
- The future of peptides in cancer treatment. (2019) (45)
- Novel systemically active galanin receptor 2 ligands in depression‐like behavior (2013) (44)
- Characteristics of Cell-Penetrating Peptide/Nucleic Acid Nanoparticles. (2016) (44)
- Uptake of cell‐penetrating peptides in yeasts (2005) (44)
- Cell-penetrating Peptides Split into Two Groups Based on Modulation of Intracellular Calcium Concentration* (2012) (43)
- Optimization of in vivo DNA delivery with NickFect peptide vectors. (2016) (43)
- New high affinity peptide antagonists to the spinal galanin receptor (1995) (43)
- Cell-penetrating peptides for siRNA delivery to glioblastomas (2018) (42)
- Novel galanin receptor subtype specific ligands in feeding regulation (2011) (42)
- Saturated Fatty Acid Analogues of Cell-Penetrating Peptide PepFect14: Role of Fatty Acid Modification in Complexation and Delivery of Splice-Correcting Oligonucleotides. (2017) (41)
- Selective stimulation of GalR1 and GalR2 in rat substantia gelatinosa reveals a cellular basis for the anti- and pro-nociceptive actions of galanin (2008) (40)
- A convergent uptake route for peptide- and polymer-based nucleotide delivery systems. (2015) (40)
- Co‐localized neuropeptide Y and GABA have complementary presynaptic effects on sensory synaptic transmission (1998) (39)
- Metabolism of galanin and galanin (1–16) in isolated cerebrospinal fluid and spinal cord membranes from rat (1995) (38)
- Design, synthesis and properties of novel powerful antioxidants, glutathione analogues (2007) (38)
- Cav1.2 and Cav1.3 L‐type calcium channels independently control short‐ and long‐term sensitization to pain (2016) (38)
- Peptide-based glioma-targeted drug delivery vector gHoPe2. (2013) (38)
- Pre-administration of PepFect6-microRNA-146a nanocomplexes inhibits inflammatory responses in keratinocytes and in a mouse model of irritant contact dermatitis. (2016) (37)
- Intrathecal administration of PNA targeting galanin receptor reduces galanin-mediated inhibitory effect in the rat spinal cord (2001) (37)
- Galanin receptors from human pituitary tumors assayed with human galanin as ligand (1993) (37)
- Intracerebroventricular administration of galanin or galanin receptor subtype 1 agonist M617 induces c-Fos activation in central amygdala and dorsomedial hypothalamus (2007) (37)
- Intracellular translocation and differential accumulation of cell-penetrating peptides in bovine spermatozoa: evaluation of efficient delivery vectors that do not compromise human sperm motility. (2013) (36)
- Role of scavenger receptors in peptide-based delivery of plasmid DNA across a blood-brain barrier model. (2016) (36)
- The Glutathione System as an Attractive Therapeutic Target (2005) (36)
- Biochemical mechanisms of calcium mobilisation induced by mastoparan and chimeric hormone-mastoparan constructs. (1998) (36)
- The Formation of Nanoparticles between Small Interfering RNA and Amphipathic Cell-Penetrating Peptides (2017) (36)
- Possible Signaling by Glutathione and Its Novel Analogue through Potent Stimulation of Frontocortical G Proteins in Normal Aging and in Alzheimer's Disease (2002) (36)
- Retro-inversion of certain cell-penetrating peptides causes severe cellular toxicity. (2011) (36)
- Bioportide: an emergent concept of bioactive cell-penetrating peptides (2012) (36)
- Isolation and characterization of galanin from sheep brain (1991) (35)
- Recent CPP-based applications in medicine (2019) (35)
- Effective in vivo gene delivery with reduced toxicity, achieved by charge and fatty acid -modified cell penetrating peptide (2017) (34)
- Status update in the use of cell-penetrating peptides for the delivery of macromolecular therapeutics (2020) (33)
- Assay for Galanin Receptor (1991) (33)
- pH-responsive PepFect cell-penetrating peptides. (2016) (32)
- Expanded ataxin-7 cause toxicity by inducing ROS production from NADPH oxidase complexes in a stable inducible Spinocerebellar ataxia type 7 (SCA7) model (2012) (31)
- Activation of peripheral galanin receptors: Differential effects on nociception (2006) (31)
- µ‐Opioid receptor activation in live cells (2008) (31)
- Chemistry and Molecular Biology of Galanin Receptor Ligands a (1998) (30)
- GalR3 activation promotes adult neural stem cell survival in response to a diabetic milieu (2013) (30)
- Multiple interaction sites of galnon trigger its biological effects (2005) (29)
- Differential regulation of adenylate cyclase activity in rat ventral and dorsal hippocampus by rat galanin (1995) (29)
- Introduction to Peptides and Proteins (2009) (29)
- N-terminal galanin fragments inhibit the hippocampal release of acetylcholine in vivo (1993) (29)
- Pituitary adenylate cyclase activating polypeptide (PACAP) redistributes the blood within the pancreas of anesthetized rats (1996) (28)
- Important pharmacophores for binding to galanin receptor 2 (2005) (28)
- The Antimicrobial and Antiviral Applications of Cell-Penetrating Peptides (2015) (28)
- Inhibition of Autophagy via p53-Mediated Disruption of ULK1 in a SCA7 Polyglutamine Disease Model (2013) (28)
- Chimeric strategies for the rational design of bioactive analogs of small peptide hormones (1997) (27)
- Cell‐penetrating peptides recruit type A scavenger receptors to the plasma membrane for cellular delivery of nucleic acids (2017) (27)
- Peripheral axotomy increases the expression of galanin message-associated peptide (GMAP) in dorsal root ganglion cells and alters the effects of intrathecal GMAP on the flexor reflex in the rat (1995) (27)
- Identification of Cell-Penetrating Peptides That Are Bactericidal to Neisseria meningitidis and Prevent Inflammatory Responses upon Infection (2013) (26)
- Cell penetration by transportan (1998) (26)
- An antioxidant tetrapeptide UPF1 in rats has a neuroprotective effect in transient global brain ischemia (2004) (25)
- NMR study of the conformation and localization of porcine galanin in SDS micelles. Comparison with an inactive analog and a galanin receptor antagonist. (1998) (25)
- PepFects and NickFects for the Intracellular Delivery of Nucleic Acids. (2015) (25)
- Galanin‐Based Peptides, Galparan and Transportan, with Receptor‐Dependent and Independent Activities (1998) (25)
- NickFect type of cell-penetrating peptides present enhanced efficiency for microRNA-146a delivery into dendritic cells and during skin inflammation. (2020) (24)
- Galaninergic signalling and adenylate cyclase (1998) (24)
- Galnon – a low-molecular weight ligand of the galanin receptors (2005) (24)
- Regulation of feeding by galnon (2004) (23)
- Differential regulation of GTPase activity by mastoparan and galparan. (1998) (23)
- Galanin pathogenic mutations in temporal lobe epilepsy. (2015) (23)
- Tumor gene therapy by systemic delivery of plasmid DNA with cell‐penetrating peptides (2018) (22)
- Glycosaminoglycans are required for translocation of amphipathic cell-penetrating peptides across membranes. (2016) (22)
- Peptide-Based Delivery of Oligonucleotides Across Blood–Brain Barrier Model (2014) (22)
- Enhancement of siRNA transfection by the optimization of fatty acid length and histidine content in the CPP. (2019) (22)
- Cell-penetrating peptide secures an efficient endosomal escape of an intact cargo upon a brief photo-induction (2013) (22)
- Role of autophagy in cell-penetrating peptide transfection model (2017) (22)
- Effects of Three Galanin Analogs on the Outward Current Evoked by Galanin in Locus Coeruleus a (1998) (22)
- Intracerebroventricular administration of galanin decreases free water intake and operant water reinforcer efficacy in water-restricted rats (2005) (22)
- Conformational analysis of galanin using end to end distance distribution observed by Förster resonance energy transfer (1997) (21)
- Molecular characterization of the ligand binding site of the human galanin receptor type 2, identifying subtype selective interactions (2007) (21)
- Cell-penetrating peptides in protein mimicry and cancer therapeutics. (2021) (21)
- The role of endocytosis in the uptake and intracellular trafficking of PepFect14-nucleic acid nanocomplexes via class A scavenger receptors. (2015) (21)
- Galanin receptors as a potential target for neurological disease (2015) (21)
- An Inert Proton Coordinated Inside a Nearly Tetrahedral Tetraamine Cavity. Synthesis and X-Ray Crystal Structure of the Aquatrichlorozincate(II) Salt of the Inside Monoprotonated Amine 1,4,8,11-Tetraazatricyclo[6.6.2.2(4,1)]octadecane. (1995) (20)
- Novel Galanin Receptor Subtype Specific Ligand in Depression Like Behavior (2013) (20)
- Assessment of new functional roles for galanin in the CNS (2005) (20)
- Formulation of Stable and Homogeneous Cell-Penetrating Peptide NF55 Nanoparticles for Efficient Gene Delivery In Vivo (2017) (20)
- Peptitergent PD1 affects the GTPase activity of rat brain cortical membranes (1999) (20)
- Peptide-based vectors: recent developments (2014) (20)
- Down-regulation of amyloid precursor protein by peptide nucleic acid oligomer in cultured rat primary neurons and astrocytes (2003) (20)
- Cell Penetrating Peptides-Hierarchical Porous Zeolitic Imidazolate Frameworks Nanoparticles: An Efficient Gene Delivery Platform (2019) (20)
- PREPARATIONS AND TEMPLATE CYCLOTETRAMERISATIONS OF 2,1,3-BENZOTHIA(SELENA)DIAZOLE-5,6-DICARBONITRILES (1995) (19)
- Toxicity, Immunogenicity, Uptake, and Kinetics Methods for CPPs. (2015) (19)
- Cell-Penetrating Mimics of Agonist-Activated G-Protein Coupled Receptors (2005) (19)
- Effective lung-targeted RNAi in mice with peptide-based delivery of nucleic acid (2019) (19)
- PHENYLIODINE(III) BIS(TRIFLUOROACETATE) AS A RADICAL CATION GENERATING REAGENT (1995) (19)
- Arginine-Rich Cell-Penetrating Peptides Require Nucleolin and Cholesterol-Poor Subdomains for Translocation across Membranes. (2018) (18)
- Regulation of GTPase and adenylate cyclase activity by amyloid β-peptide and its fragments in rat brain tissue (1999) (18)
- Fuxe, K. et al. Intramembrane receptor-receptor interactions: a novel principle in molecular medicine. J. Neural Transm. 114, 49-75 (2007) (18)
- Cholesterol prevents interaction of the cell‐penetrating peptide transportan with model lipid membranes (2008) (18)
- Ala5-galanin (2–11) is a GAL2R specific galanin analogue (2016) (18)
- Galanin receptor binding studies in the membranes of cultured cells measured by fluorescence correlation spectroscopy (1999) (17)
- Targeting of antisense PNA oligomers to human galanin receptor type 1 mRNA (2004) (17)
- Binding of Chimeric Peptides M617 and M871 to Galanin Receptor Type 3 Reveals Characteristics of Galanin Receptor–Ligand Interaction (2010) (17)
- Optimized luciferase assay for cell-penetrating peptide-mediated delivery of short oligonucleotides. (2015) (17)
- Tumour Targeting with Rationally Modified Cell-Penetrating Peptides (2012) (17)
- Uptake Mechanisms of Cell-Penetrating Peptides Derived from the Alzheimer’s Disease Associated Gamma-Secretase Complex (2006) (16)
- PROPERTIES OF MIXED-LIGAND CYCLOMETALATED PLATINUM(II) COMPLEXES DERIVED FROM 2-PHENYLPYRIDINE AND 2-(2'-THIENYL)PYRIDINE : VOLTAMMETRIC, ABSORPTION A ND EMISSION STUDIES (1995) (16)
- Cell‐penetrating peptides as antifungals towards Malassezia sympodialis (2012) (16)
- Targeting cytokine expression in glial cells by cellular delivery of an NF-κB decoy (2007) (16)
- Intracellular Delivery of Short Interfering RNA in Rat Organ of Corti Using a Cell-penetrating Peptide PepFect6 (2012) (16)
- Cell-Penetrating Peptides and Transportan (2021) (15)
- A study of the interaction of some neuropeptides and their analogs with bilayer lipid membranes and liposomes (1997) (15)
- Novel, cell‐penetrating molecular transporters with flexible backbones and permanently charged side‐chains (2007) (14)
- Combination with antimicrobial peptide lyses improves loop-mediated isothermal amplification based method for Chlamydia trachomatis detection directly in urine sample (2016) (14)
- The effect of main urine inhibitors on the activity of different DNA polymerases in loop-mediated isothermal amplification (2017) (14)
- Synthesis of N-protected erythro-phenylalanylepoxides (1995) (14)
- Effect of a Fusion Peptide by Covalent Conjugation of a Mitochondrial Cell-Penetrating Peptide and a Glutathione Analog Peptide (2017) (14)
- Rotational Barriers and the Number of Stereoisomers of Iodixanol, an X-Ray Contrast Agent. (1995) (14)
- Determining receptor–ligand interaction of human galanin receptor type 3 (2010) (14)
- Mutagenesis Study on Human Galanin Receptor GalR1 Reveals Domains Involved in Ligand Binding a (1998) (14)
- Thermochemical and Structural Investigations on the Systems NaCl/TbCl3 and NaCl/DyCl3. (1995) (13)
- N-Terminally elongated fragments of galanin(1–16) inhibit insulin secretion from isolated mouse islets (1994) (13)
- Approaches for the discovery of new cell-penetrating peptides (2020) (13)
- Expression of galanin receptor-1 (GALR1) in the rat trigeminal ganglia and molar teeth (2002) (13)
- Co-transduction of Sleeping Beauty Transposase and Donor Plasmid via a Cell-penetrating Peptide: A simple one step Method (2008) (13)
- Peptide Nanoparticle Delivery of Charge-Neutral Splice-Switching Morpholino Oligonucleotides (2015) (13)
- Intracellular Target-Specific Accretion of Cell Penetrating Peptides and Bioportides: Ultrastructural and Biological Correlates. (2016) (13)
- Methods to follow intracellular trafficking of cell-penetrating peptides (2016) (12)
- Functional effects and ligand binding of chimeric galanin‐neuropeptide Y (NPY) peptides on NPY and galanin receptor types (1994) (12)
- GABAergic terminals are a source of galanin to modulate cholinergic neuron development in the neonatal forebrain. (2014) (12)
- Peptide-Ligand Binding Modeling of siRNA with Cell-Penetrating Peptides (2014) (12)
- Simultaneous membrane interaction of amphipathic peptide monomers, self-aggregates and cargo complexes detected by fluorescence correlation spectroscopy. (2018) (12)
- Effects of vasopressin–mastoparan chimeric peptides on insulin release and G-protein activity (1999) (11)
- Application of CPPs for Brain Delivery. (2015) (11)
- Role of third intracellular loop of galanin receptor type 1 in signal transduction (2000) (10)
- Characterisation of a new chimeric ligand for galanin receptors: galanin(1–13)-[d-Trp32]-neuropeptide Y(25–36)amide (2001) (10)
- Comparison of Peptide- and Lipid-Based Delivery of miR-34a-5p Mimic into PPC-1 Cells. (2017) (10)
- Novel viral vectors utilizing intron splice-switching to activate genome rescue, expression and replication in targeted cells (2011) (10)
- GALANIN RECEPTOR LIGANDS AS POTENTIAL THERAPEUTIC AGENTS IN DEPRESSION AND NEURODEGENERATION (1995) (10)
- Central Administration of Galanin Receptor 1 Agonist Boosted Insulin Sensitivity in Adipose Cells of Diabetic Rats (2016) (10)
- Attempt to solubilize Na+/K+-exchanging ATPase with amphiphilic peptide PD1. (1997) (10)
- Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models (2021) (9)
- Solvent stabilized solution structures of galanin and galanin analogs, studied by circular dichroism spectroscopy. (1995) (9)
- TRANSITION STATES IN THE CRYSTALLINE PHASE ? THERMAL REARRANGEMENTS OF SOLID 4H-1,2,4-TRIAZOLES (1995) (9)
- Galanin, through GalR1 but not GalR2 receptors, decreases motivation at times of high appetitive behavior (2013) (9)
- Cell-Penetrating Peptides Delivering siRNAs: An Overview. (2021) (9)
- Refinement of a Quantitative Structure–Activity Relationship Model for Prediction of Cell-Penetrating Peptide Based Transfection Systems (2017) (9)
- p53 Latency: C-Terminal Domain Prevents Binding of p53 Core to Target but not to Nonspecific DNA Sequences (2001) (9)
- OLIGOMERIZATION OF ETHYLENE WITH CATIONIC PHENANTHROLINE(METHYL)PALLADIUM COMPLEXES (1995) (9)
- Studies of cell-penetrating peptides by biophysical methods (2022) (9)
- An update on cell-penetrating peptides with intracellular organelle targeting (2022) (9)
- Role of the third cytoplasmic loop in signal transduction by galanin receptors. (1997) (9)
- Development of a novel nanoparticle by dual modification with the pluripotential cell-penetrating peptide PepFect6 for cellular uptake, endosomal escape, and decondensation of an siRNA core complex. (2013) (8)
- On the solution structure of galanin (1991) (8)
- Human Protein 53-Derived Cell-Penetrating Peptides (2012) (8)
- Transfection of Infectious RNA and DNA/RNA Layered Vectors of Semliki Forest Virus by the Cell-Penetrating Peptide Based Reagent PepFect6 (2013) (8)
- Analysis of T3SS-independent autonomous internalization of the bacterial effector protein SspH1 from Salmonella typhimurium (2014) (8)
- Intracerebroventricularly administered galanin does not alter operant reaction time or differentially reinforced high rate schedule operant responding in rats (2004) (8)
- THE MECHANISM OF RUO4-MEDIATED OXIDATIONS OF ETHERS: ISOTOPE EFFECTS, SOLVENT EFFECTS AND SUBSTITUENT EFFECTS (1995) (7)
- Amyloid-like Self-Assembly of a Hydrophobic Cell-Penetrating Peptide and Its Use as a Carrier for Nucleic Acids. (2021) (7)
- Galparan induces in vivo acetylcholine release in the frontal cortex (1997) (7)
- Targeting Strategies (2019) (7)
- Intracellular delivery of therapeutic antisense oligonucleotides targeting mRNA coding mitochondrial proteins by cell-penetrating peptides. (2020) (7)
- Comparison of the solution structures of the chimeric peptides galanin(1-12)-Ala-neuropeptide Y(25-36)amide and galanin(1-12)-Pro-neuropeptide Y(25-36)amide. (1994) (7)
- Toxicity methods for cell-penetrating peptides (2007) (7)
- Conformations and Rotational Barriers in NADH and NAD+ Analogues. A Dynamic NMR and Molecular Mechanics Investigation. (1995) (7)
- A High-Throughput Kinetic Assay for RNA-Cleaving Deoxyribozymes (2015) (6)
- THERMODYNAMIC ACIDITIES AND HOMOLYTIC METAL-HYDROGEN BOND ENERGIES OF GROUP 8 PROTONATED DECAMETHYLMETALLOCENES CP*2MH+(M=RU, OS) (1995) (6)
- Binding of chimeric npy/galanin peptides M32 and M242 to cloned neuropeptide Y receptor subtypes Y1, Y2, Y4, and Y5 (2001) (6)
- Molecular pharmacology of receptors for calcitonin-gene-related peptide , amylin and adrenomedullin (2009) (6)
- An improved synthesis of releasable luciferin–CPP conjugates (2009) (6)
- SCARA Involvement in the Uptake of Nanoparticles Formed by Cell-Penetrating Peptides. (2015) (6)
- Pharmacological stimulation of GAL1R but not GAL2R attenuates kainic acid-induced neuronal cell death in the rat hippocampus (2016) (6)
- A study of melittin, motilin and galanin in reversed micellar environments, using circular dichroism spectroscopy. (1996) (6)
- CPP-Based Delivery System for In Vivo Gene Delivery. (2015) (6)
- Modulating Anti-MicroRNA-21 Activity and Specificity Using Oligonucleotide Derivatives and Length Optimization (2012) (6)
- Galanin receptor ligands in the hippocampus: Galanin, N-terminal galanin fragments and analogs (1991) (5)
- Twenty-Five Years of Galanin Research (2009) (5)
- Central and sensory galanin neurons and functional aspects (1992) (5)
- Cell-Penetrating Peptides in Cancer Targeting (2011) (5)
- Cellular Uptake of Cell-Penetrating Peptides (2004) (5)
- Calcium-mobilizing actions of chimeric hormone-mastoparan peptides. (1997) (5)
- Purification of a galanin degrading 70 kDa metallo-peptidase from bovine spinal cord (1998) (5)
- The structure of the rodent and porcine neuropeptide galanin and antagonists as determined by FTIR and CD spectroscopy (1994) (5)
- Astrocytes promote ethanol-induced enhancement of intracellular Ca2+ signals through intercellular communication with neurons (2021) (5)
- On the Absence of 2-(2'-Cyclopentenyl)glycine-Derived Cyanogenic Glycosides in Cassava, Manihot esculenta Crantz. (1995) (5)
- ACE2 Peptide Fragment Interaction with Different S1 Protein Sites (2021) (5)
- The Internalization Mechanisms and Bioactivity of the Cell‐Penetrating Peptides (2009) (4)
- Galanin and perseveration (2005) (4)
- Transcriptional Profiling Reveals Ribosome Biogenesis, Microtubule Dynamics and Expression of Specific lncRNAs to be Part of a Common Response to Cell-Penetrating Peptides (2020) (4)
- COMPLEXATION AND DECOMPOSITION OF BENZENEDIAZONIUM TETRAFLUOROBORATE IN THE PRESENCE OF ACYCLIC POLYETHERS IN 1,2-DICHLOROETHANE AND IN THE GAS PHASE (1995) (4)
- Cell-Penetrating Peptides Targeting Mitochondria (2018) (4)
- Quantitative Microplate Assay for Real-Time Nuclease Kinetics (2016) (4)
- Photochemical Nitration by Tetranitromethane. Part XXIV. Adduct Formation in the Photochemical Reaction of 1,4,6,7-Tetramethylnaphthalene; Some Rearrangement Studies of 1,4,6,7-Tetramethyl-r-1-nitro-t-4-trinitromethyl-1,4-dihydronaphthalene and Evidence for Inverted Spin Trapping of Trinitromethanid (1995) (4)
- Role of cysteine 341 and arginine 348 of GLP-1 receptor in G-protein coupling (2007) (4)
- Classes and Applications of Cell-Penetrating Peptides (2019) (4)
- Intracellular Delivery of Short Interfering RNA in Rat Organ of Corti Using a Cell-penetrating Peptide PepFect6. (2012) (4)
- PepFect6 Mediated SiRNA Delivery into Organotypic Cultures. (2016) (3)
- Synthesis and Applications of Cell-Penetrating Peptide—PNA Conjugates (2005) (3)
- Effect of small molecule signaling in PepFect14 transfection (2020) (3)
- A rhegnylogic strategy for the synthesis of signal transduction modulatory, cell penetrating peptides (2006) (3)
- Cell-Translocation Mechanisms of CPPs (2019) (3)
- Galanin receptor ligands (2015) (3)
- Predicting Transiently Expressed Protein Yields: Comparison of Transfection Methods in CHO and HEK293 (2022) (3)
- PREPARATION OF TWO AGGRESSION CONTROLLING SUBSTANCES IN BEES (1995) (3)
- Vectorization of splice-correcting oligonucleotides with cell-penetrating peptides (2013) (3)
- Ligand binding and functional effects of systematic double d-amino acid residue substituted neuropeptide Y analogs on Y1 and Y2 receptor types (1996) (3)
- Advances in peptide delivery (2015) (3)
- Novel Efficient Cell-Penetrating, Peptide-Mediated Strategy for Enhancing Telomerase Inhibitor Oligonucleotides. (2015) (3)
- Approaches for evaluation of novel CPP-based cargo delivery systems (2022) (3)
- Distribution of CPP-Protein Complexes in Freshly Resected Human Tissue Material (2010) (2)
- LINKS BETWEEN THE THEORETICAL RATE LAW AND THE EXPERIMENTAL RESPONSE SURFACE : AN EXAMPLE WITH A SOLVOLYSIS REACTION (1995) (2)
- CRISPR/Cas9 Plasmid Delivery Through the CPP: PepFect14. (2021) (2)
- Synthesis of N‐Protected erythro‐Phenylalanylepoxides. (1996) (2)
- Spatial orientation of n-alkanesulfonyl chlorides in the active center of cholinesterases (1989) (2)
- X-Ray Crystallographic Study of Tetrammine-Carbonatocobalt(III) Sulfate Trihydrate, [Co(NH3)4CO3]2SO4.3H2O. (1995) (2)
- Improvement of Transfection with PepFects Using Organic and Inorganic Materials. (2021) (2)
- Cell-penetrating peptide fusion proteins (2013) (2)
- STRUCTURAL STUDIES OF A PARTICULATE X-RAY CONTRAST AGENT : A MULTI-METHOD APPROACH (1995) (2)
- Lipid-protein interactions in neurotropic Na-pump regulation. (1992) (1)
- Nucleic Acid– Binding Proteins (2009) (1)
- Peptide mimetics of receptor extracellular domains modulate signal transduction by P2Y2 receptors (2002) (1)
- Methods for Structural Studies of CPPs (2019) (1)
- Sequence Analysis and Function Prediction (2009) (1)
- p53-mediated disruption of FIP200 function cause autophagic dysregulation in a SCA7 polyglutamine disease model (2013) (1)
- PepFect15, a novel endosomolytic cell-penetrating peptide for non-covalent oligonucleotide delivery (2012) (1)
- STRUCTURAL FEATURES OF AMPHIPATHIC PEPTIDES REQUIRED FOR THE ACTIVATION OFG-PROTEINS (1998) (1)
- Role of autophagy in PepFect14 transfection (2017) (1)
- Structure – activity relationship study of the cell-penetrating peptide p VEC (2006) (1)
- Mimicry of Dopamine 1 Receptor Signaling with Cell-Penetrating Peptides (2020) (1)
- ACE2 peptide fragment interacts with several sites on the SARS-CoV-2 spike protein S1 (2020) (1)
- Nucleic Acid–Binding Proteins (2009) (1)
- New strategy for siRNA delivery to glioblastoma cells by cell-penetrating peptide (2017) (1)
- Microbial membrane-penetrating peptides and their application (2007) (1)
- Galanin message associated peptide (1992) (1)
- Magnetic Nanoparticle Assisted Self-assembly of Cell Penetrating Peptides-Oligonucleotides Complexes for Gene Delivery (2017) (1)
- DISSERTATIONES TECHNOLOGIAE UNIVERSITATIS TARTUENSIS 30 LY PÄRNASTE How , why , what and where : Mechanisms behind CPP / cargo nanocomplexes (2016) (1)
- Therapeutic Potential of CPPs (2019) (1)
- Synthesis of NickFects, a New Family of CPPs, by Solid-Phase Peptide Synthesis. (2020) (1)
- Differential Role of Galanin Receptors in the Regulation of Depression-Like Behavior and Monoamine/Stress-Related Genes at the Cell Body Level (2008) (1)
- Peptide-Based Delivery of Oligonucleotides Across Blood–Brain Barrier Model (2013) (1)
- Design and synthesis of cell-penetrating peptides (2007) (1)
- Editorial [Hot Topic: Cell-Penetrating Peptides, Mechanisms and Applications (Executive Editor: Ulo Langel)] (2005) (1)
- A Second Life for MAP, a Model Amphipathic Peptide (2022) (1)
- Deletion analogues of transportan (2000) (1)
- Synthesis of β‐amyloid precursor peptide and presenilin segments (2001) (1)
- Purification and Characterization of Proteins (2009) (1)
- A galanin(2-11) analogue specific for GalR2 (2011) (0)
- Design and Synthesis of a Peptide-Based Glioma-Targeted Drug Delivery Vector gHope2. (2021) (0)
- Introduction to Part IV (2009) (0)
- Methods to study the translocation of cell-penetrating peptides (2007) (0)
- Role of autophagy in cell-penetrating peptide transfection model (2017) (0)
- The quest for a GPCR selective ligand – a bottleneck (2011) (0)
- Utilization of Cell-Penetrating Peptides for In Vivo Delivery of Bioactive Cargo: The Effect of Nanoparticle Formulation. (2021) (0)
- In Silico Studies to Support Vaccine Development (2023) (0)
- Delivering catalase to yeast peroxisomes using cell-penetrating peptides (2011) (0)
- (cid:1) -Opioid receptor activation in live cells (2008) (0)
- Synthetic galanin analogs with biochemical activity (1991) (0)
- Methods for CPP Functionalization (2019) (0)
- p53-mediated disruption of FIP200 function cause autophagic dysregulation in a SCA7 polyglutamine disease model (2013) (0)
- Cell-Penetrating Peptides Predicted From CASC3, AKIP1, and AHRR Proteins (2021) (0)
- Pharmacological stimulation of galanin receptor 1 but not galanin receptor 2 attenuates kainic acid-induced neuronal cell death in the rat hippocampus (2012) (0)
- Galanin receptor agonists protect against kainic acid-induced excitotoxicity in the rat hippocampus (2011) (0)
- SIGNAL TRANSDUCTION BY GALANIN RECEPTOR (1997) (0)
- SÄDE VIIRLAID Novel glutathione analogues and their antioxidant activity (2011) (0)
- NIKITA OSKOLKOV A novel strategy for peptide-mediated cellular delivery and induction of endosomal escape (2011) (0)
- Amphipathic CPPs upregulate Ca in cells’ cytosol and induce lysosomal exocytosis (2010) (0)
- Protein–Ligand Interactions (2009) (0)
- Corrigendum to “Effects of galnon, a non-peptide galanin-receptor agonist, on insulin release from rat pancreatic islets” [Biochem. Biophys. Res. Commun. 328 (2005) 213–220] (2008) (0)
- A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors (2018) (0)
- P3-278 Transcription factors as targets to block inflammation in neurodegenerative disorders (2006) (0)
- Distinct uptake routes of CPPs and differential dependence of heparan sulfate for internalization (2008) (0)
- TAAVI LEHTO Delivery of nucleic acids by cell-penetrating peptides: application in modulation of gene expression (2011) (0)
- Novel peptide agonists, favoring galanin receptor type 2 over galanin receptor type 1 and 3 (2009) (0)
- The interaction of CGRP with its receptors (2002) (0)
- Synthesis of Cell-Penetrating Peptides for Cargo Delivery (2006) (0)
- Tumour Targeting with Rationally Modified Cell-Penetrating Peptides (2012) (0)
- Effective in vivo gene delivery with reduced toxicity, achieved by charge and fatty acid -modified cell penetrating peptide (2017) (0)
- Expanded ataxin-7 cause toxicity by inducing ROS production from NADPH oxidase complexes in a stable inducible Spinocerebellar ataxia type 7 (SCA7) model (2012) (0)
- Receptor subtype selective galanin analogous for better understanding of the role of galanin in cancer progression (2010) (0)
- Intracellular third loop of galanin receptor as G-protein interaction site (2002) (0)
- Receptor ligands to delineate the galaninergic system (2010) (0)
- Cell-Penetrating Peptides. Preface. (2015) (0)
- Target-activated cell-penetrating peptide (2009) (0)
- Mimicking p14ARF with a Cell-Penetrating Peptide (2007) (0)
- Bioportide: an emergent concept of bioactive cell-penetrating peptides (2012) (0)
- Identification of important pharmacophores in the galanin receptor subtypes (2010) (0)
- Aggregation Limiting Cell-Penetrating Peptides Derived from Protein Signal Sequences (2023) (0)
- Mitochondrial Targeting Probes, Drug Conjugates, and Gene Therapeutics. (2021) (0)
- Kinetics of CPPs Cellular Uptake (2019) (0)
- Cell-penetrating short interfering RNAs and decoy oligonucleotides (2007) (0)
- Peptides and Proteins as Drugs (2009) (0)
- Endpoint and Kinetic Approaches for Assessing Transfection Efficacy in Mammalian Cell Culture. (2021) (0)
- Different strategies to inhibit NF-κB in order to sensitize Stypehuman neuroblastoma cells to TRAIL-induced apoptosis (2012) (0)
- RNA interference as antiviral therapy against Peste des Petits Ruminants: proof of concept of in vivo efficiency using a small animal model (2015) (0)
- The quest for a GPCR subtype selective ligand for the galanin system: development and utilization (2012) (0)
- Recent developments in applications of cell penetrating peptides uptake mechanisms and oligonucleotide delivery (2012) (0)
- Expressed therapeutic protein yields are predicted by transiently transfected mammalian cell population (2022) (0)
- Galanin receptor ligands: agonists and antagonists (1992) (0)
- M1154 – A novel galanin ligand to delineate the galaninergic system (2010) (0)
- Introduction to Part V (2009) (0)
- Intracellular Delivery of Nanoparticles with CPPs (2006) (0)
- Cellular delivery of oligonucleotides by PepFect (2010) (0)
- Chimeric Mastoparans: Biological Probes and Designer Secretagogues (2001) (0)
- Methods and compositions for the identification of RNA-binding proteins (2004) (0)
- Introduction (2019) (0)
- Inhibition of tumor growth by chlorambucil conjugated to a new tumor targeting peptide vector (2008) (0)
- Selected Classes of Bioactive Peptides (2009) (0)
- Cell Surface Receptors and Signaling (2009) (0)
- Independent activation of 5-hydroxytryptamine secretion and Phospholipase D: A study with chimeric Mastroparan-containing secretagogues in RBL-2H3 cells (2000) (0)
- Peptides targeting mitochondria for efficient delivery of therapeutic biomolecules (2018) (0)
- Human Protein 53-Derived Cell-Penetrating Peptides (2012) (0)
- Nuclear Magnetic Resonance (NMR) (2009) (0)
- Transfection of Heat Shock Protein 70 kDa (HSP70) (2022) (0)
- Galanin antagonists M15 and M35: differential effects on striatal acetylcholine release (1993) (0)
- Inhibition of Autophagy via p53-Mediated Disruption of ULK1 in a SCA7 Polyglutamine Disease Model (2013) (0)
- Cellular trafficking of cell penetrating peptides and protein transport over plasma membrane (2007) (0)
- Applications of Cell-Penetrating Peptides as Signal Transduction Modulators (2006) (0)
- Radiolabeling and characterization of binding sites for the galanin receptor antagonist M35 (1992) (0)
- Cell-penetration and membrane leakage by peptides derived from the N-termini of prion proteins (2004) (0)
- 314 PepFect6-miRNA-146a nanocomplexes inhibit inflammatory responses in keratinocytes and in a mouse model of irritant contact dermatitis (2016) (0)
- Neisseria meningitidis and Prevent Inflammatory Responses upon (2013) (0)
- Protein Delivery and Mimicry (2019) (0)
- 10 Mechanisms of Cargo Delivery by Transportans (2006) (0)
- Mimicry of Dopamine 1 Receptor Signaling with Cell-Penetrating Peptides (2020) (0)
- Novel Galanin Receptor Subtype Specific Ligand in Depression Like Behavior (2012) (0)
- Small molecule signaling in PepFect 14 transfection (2019) (0)
- Synthesis of Cell-Penetrating Peptide-PNA Constructs (2003) (0)
- Chemical Synthesis of Peptides and Proteins (2009) (0)
- β-adrenergic modulation of glucose uptake through GLUT1 (2008) (0)
- Galanin pathogenicmutations in temporal lobe epilepsy (2015) (0)
- Mechanisms of prion antagonization by PrP-derived cell-penetrating peptides (2010) (0)
- Differential secretion from mast cells induced by novel mastoparan analogues (2001) (0)
- Chimeric hormones and neuropeptides. (1997) (0)
- IMRE MÄGER Characterization of cell-penetrating peptides: assessment of cellular internalization kinetics, mechanisms and bioactivity (2011) (0)
- GPCR-ligands influence the short oligonucleotide transfection efficacy of the cell-penetrating peptide; Pepfect14 (2015) (0)
- Cell-penetrating peptide secures an efficient endosomal escape of an intact cargo upon a brief photo-induction (2013) (0)
- Protein Engineering and Gene Silencing (2009) (0)
- Refinement of a Quantitative Structure–Activity Relationship Model for Prediction of Cell-Penetrating Peptide Based Transfection Systems (2016) (0)
- Toxicity and Immune Response (2019) (0)
- Tissue Analysis of Lung-Targeted Delivery of siRNA and Plasmid DNA. (2021) (0)
- Methods for Detection and Visualization of CPPs (2019) (0)
- Corrigendum to 'Cell-penetrating peptides in protein mimicry and cancer therapeutics' [Advanced Drug Delivery Reviews, 180 (2022), 114044]. (2022) (0)
- Implementation of antimicrobial peptides for sample preparation prior to nucleic acid amplification in point-of-care settings (2017) (0)
- PepFect14 Signaling and Transfection. (2021) (0)
- Clinical Trials and Commercialization Using CPPs (2019) (0)
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