Ulrich Dirnagl
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(Suggest an Edit or Addition)Ulrich Dirnagl's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Pathobiology of ischaemic stroke: an integrated view (1999) (3839)
- The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research (2020) (1973)
- Near infrared spectroscopy (NIRS): A new tool to study hemodynamic changes during activation of brain function in human adults (1993) (1075)
- The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research (2020) (961)
- Ischemic tolerance and endogenous neuroprotection (2003) (825)
- Stroke-induced Immunodeficiency Promotes Spontaneous Bacterial Infections and Is Mediated by Sympathetic Activation Reversal by Poststroke T Helper Cell Type 1–like Immunostimulation (2003) (807)
- Central nervous system injury-induced immune deficiency syndrome (2005) (768)
- Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0 (2019) (762)
- Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation (2016) (703)
- Targeting gene-modified hematopoietic cells to the central nervous system: Use of green fluorescent protein uncovers microglial engraftment (2001) (641)
- Coupling of brain activity and cerebral blood flow: basis of functional neuroimaging. (1995) (614)
- Preconditioning and tolerance against cerebral ischaemia: from experimental strategies to clinical use (2009) (555)
- Continuous Measurement of Cerebral Cortical Blood Flow by Laser—Doppler Flowmetry in a Rat Stroke Model (1989) (498)
- Cortical spreading ischaemia is a novel process involved in ischaemic damage in patients with aneurysmal subarachnoid haemorrhage (2009) (497)
- Erythropoietin Is a Paracrine Mediator of Ischemic Tolerance in the Brain: Evidence from an In Vitro Model (2002) (483)
- Estrogen Increases Bone Marrow‐Derived Endothelial Progenitor Cell Production and Diminishes Neointima Formation (2003) (482)
- Bone Marrow–Derived Progenitor Cells Modulate Vascular Reendothelialization and Neointimal Formation: Effect of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibition (2002) (479)
- Vascular imprints of neuronal activity: relationships between the dynamics of cortical blood flow, oxygenation, and volume changes following sensory stimulation. (1997) (471)
- Simultaneous Recording of Cerebral Blood Oxygenation Changes during Human Brain Activation by Magnetic Resonance Imaging and Near-Infrared Spectroscopy (1996) (460)
- Biomedical research: increasing value, reducing waste (2014) (448)
- Stroke and the immune system: from pathophysiology to new therapeutic strategies (2011) (415)
- Atorvastatin Upregulates Type III Nitric Oxide Synthase in Thrombocytes, Decreases Platelet Activation, and Protects From Cerebral Ischemia in Normocholesterolemic Mice (2000) (402)
- Stroke-Induced Immunodepression: Experimental Evidence and Clinical Relevance (2007) (401)
- Decrease in parietal cerebral hemoglobin oxygenation during performance of a verbal fluency task in patients with Alzheimer's disease monitored by means of near-infrared spectroscopy (NIRS) — correlation with simultaneous rCBF-PET measurements (1997) (366)
- Pericytes in capillaries are contractile in vivo, but arterioles mediate functional hyperemia in the mouse brain (2010) (356)
- Bench to Bedside: The Quest for Quality in Experimental Stroke Research (2006) (350)
- Pathophysiology of Stroke: Lessons from Animal Models (2004) (343)
- Mechanisms of stroke protection by physical activity (2003) (322)
- Evidence for the Efficacy of NXY-059 in Experimental Focal Cerebral Ischaemia Is Confounded by Study Quality (2008) (313)
- Hypoxia-Induced Stroke Tolerance in the Mouse Is Mediated by Erythropoietin (2003) (299)
- Role of glial cells in cerebral ischemia (2005) (291)
- Capillary perfusion of the rat brain cortex. An in vivo confocal microscopy study. (1994) (291)
- Increased Formation of Reactive Oxygen Species after Permanent and Reversible Middle Cerebral Artery Occlusion in the Rat (1998) (289)
- Tolerance Against Ischemic Neuronal Injury Can Be Induced by Volatile Anesthetics and Is Inducible NO Synthase Dependent (2002) (287)
- Rosuvastatin, a new HMG-CoA reductase inhibitor, upregulates endothelial nitric oxide synthase and protects from ischemic stroke in mice (2002) (286)
- Nitric Oxide Scavenging by Hemoglobin or Nitric Oxide Synthase Inhibition by N-Nitro-L-Arginine Induces Cortical Spreading Ischemia When K+ Is Increased in the Subarachnoid Space (1998) (281)
- Reprint: Good Laboratory Practice: Preventing Introduction of Bias at the Bench (2009) (274)
- Angiotensin AT2 receptor protects against cerebral ischemia‐induced neuronal injury (2005) (271)
- DNA Methyltransferase Contributes to Delayed Ischemic Brain Injury (2000) (270)
- Neogenesis of cerebellar Purkinje neurons from gene-marked bone marrow cells in vivo (2001) (265)
- Neuroprotective role of astrocytes in cerebral ischemia: Focus on ischemic preconditioning (2005) (265)
- Products of hemolysis in the subarachnoid space inducing spreading ischemia in the cortex and focal necrosis in rats: a model for delayed ischemic neurological deficits after subarachnoid hemorrhage? (2000) (255)
- Attenuated stroke severity after prodromal TIA: a role for ischemic tolerance in the brain? (1999) (253)
- Improving Outcome after Stroke: Overcoming the Translational Roadblock (2008) (248)
- Cerebral oxygenation changes in response to motor stimulation. (1996) (248)
- Stroke-induced immunodepression and post-stroke infections: Lessons from the preventive antibacterial therapy in stroke trial (2009) (246)
- Protective effects of PJ34, a novel, potent inhibitor of poly(ADP-ribose) polymerase (PARP) in in vitro and in vivo models of stroke. (2001) (245)
- Mild Cerebral Ischemia Induces Loss of Cyclin-Dependent Kinase Inhibitors and Activation of Cell Cycle Machinery before Delayed Neuronal Cell Death (2001) (240)
- Preventive Antibacterial Therapy in Acute Ischemic Stroke: A Randomized Controlled Trial (2008) (235)
- Physical Activity Improves Long-Term Stroke Outcome via Endothelial Nitric Oxide Synthase–Dependent Augmentation of Neovascularization and Cerebral Blood Flow (2006) (231)
- Role of nitric oxide in the coupling of cerebral blood flow to neuronal activation in rats (1993) (228)
- Cerebrovascular complications of bacterial meningitis in adults (1992) (227)
- Characterization of CBF response to somatosensory stimulation: model and influence of anesthetics. (1993) (226)
- Empirical Evidence of Bias in the Design of Experimental Stroke Studies: A Metaepidemiologic Approach (2008) (224)
- Cellular Immunodepression Preceding Infectious Complications after Acute Ischemic Stroke in Humans (2007) (215)
- Immune surveillance of mouse brain perivascular spaces by blood‐borne macrophages (2001) (209)
- Results of a preclinical randomized controlled multicenter trial (pRCT): Anti-CD49d treatment for acute brain ischemia (2015) (204)
- Neuroprotective effects of atorvastatin against glutamate‐induced excitotoxicity in primary cortical neurones (2005) (202)
- The neurovascular unit as a selective barrier to polymorphonuclear granulocyte (PMN) infiltration into the brain after ischemic injury (2012) (196)
- Stroke induced Sarcopenia: muscle wasting and disability after stroke. (2013) (195)
- Coupling of cerebral blood flow to neuronal activation: role of adenosine and nitric oxide. (1994) (195)
- Desferrioxamine Induces Delayed Tolerance against Cerebral Ischemia in Vivo and in Vitro (2002) (190)
- Serial Analysis of Gene Expression Identifies Metallothionein-II as Major Neuroprotective Gene in Mouse Focal Cerebral Ischemia (2002) (188)
- Endothelin-1 potently induces Leão's cortical spreading depression in vivo in the rat: a model for an endothelial trigger of migrainous aura? (2002) (187)
- Physical model for the spectroscopic analysis of cortical intrinsic optical signals. (2000) (185)
- Human cerebrospinal fluid monoclonal N-methyl-D-aspartate receptor autoantibodies are sufficient for encephalitis pathogenesis. (2016) (185)
- Distinguishing between Exploratory and Confirmatory Preclinical Research Will Improve Translation (2014) (183)
- Pathobiology of injury after stroke: the neurovascular unit and beyond (2012) (178)
- The ARRIVE guidelines 2.0: updated guidelines for reporting animal research (2020) (178)
- Essential role of interleukin-6 in post-stroke angiogenesis. (2012) (174)
- The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research (2020) (174)
- The ARRIVE guidelines 2019: updated guidelines for reporting animal research (2019) (173)
- Increased Hypoxic Tolerance by Chemical Inhibition of Oxidative Phosphorylation: “Chemical Preconditioning” (1997) (172)
- Stroke Propagates Bacterial Aspiration to Pneumonia in a Model of Cerebral Ischemia (2006) (172)
- Autoregulation of Cerebral Blood Flow in Experimental Focal Brain Ischemia (1990) (172)
- Modeling Stroke in Mice - Middle Cerebral Artery Occlusion with the Filament Model (2011) (172)
- Withdrawal of Statin Treatment Abrogates Stroke Protection in Mice (2003) (169)
- Differential Mechanisms of Neuroprotection by 17 β-Estradiol in Apoptotic versus Necrotic Neurodegeneration (2001) (163)
- The Hong Kong Principles for assessing researchers: Fostering research integrity (2019) (163)
- Found in translation: preclinical stroke research predicts human pathophysiology, clinical phenotypes, and therapeutic outcomes. (2014) (160)
- Sulfonylureas Improve Outcome in Patients With Type 2 Diabetes and Acute Ischemic Stroke (2007) (160)
- Age Dependency of Changes in Cerebral Hemoglobin Oxygenation during Brain Activation: A Near-Infrared Spectroscopy Study (1995) (158)
- No Evidence for Early Decrease in Blood Oxygenation in Rat Whisker Cortex in Response to Functional Activation (2001) (157)
- Endogenous neuroprotection: Mitochondria as gateways to cerebral preconditioning? (2008) (157)
- Nitric oxide: a modulator, but not a mediator, of neurovascular coupling in rat somatosensory cortex. (1999) (156)
- Global Cerebral Ischemia in the Rat: Online Monitoring of Oxygen Free Radical Production Using Chemiluminescence in vivo (1995) (156)
- Assessment of local brain activation. A simultaneous PET and near-infrared spectroscopy study. (1997) (153)
- Spinal cord injury-induced immune deficiency syndrome enhances infection susceptibility dependent on lesion level. (2016) (150)
- Cerebral endothelial cells release TNF-alpha after stimulation with cell walls of Streptococcus pneumoniae and regulate inducible nitric oxide synthase and ICAM-1 expression via autocrine loops. (1999) (140)
- Depletion of Cultivatable Gut Microbiota by Broad-Spectrum Antibiotic Pretreatment Worsens Outcome After Murine Stroke (2016) (137)
- ZK200775: a phosphonate quinoxalinedione AMPA antagonist for neuroprotection in stroke and trauma. (1998) (135)
- Turnover of Rat Brain Perivascular Cells (2001) (134)
- Induction of tolerance in rat cortical neurons: hypoxic preconditioning (1997) (133)
- Circulating monocytic cells infiltrate layers of anterograde axonal degeneration where they transform into microglia (2005) (131)
- Non-invasive functional mapping of the human motor cortex using near-infrared spectroscopy. (1996) (128)
- Preventive Antibacterial Treatment Improves the General Medical and Neurological Outcome in a Mouse Model of Stroke (2003) (124)
- Microvascular Changes during the Early Phase of Experimental Bacterial Meningitis (1990) (123)
- Improved Reperfusion and Neuroprotection by Creatine in a Mouse Model of Stroke (2007) (122)
- IL-1β Stimulates COX-2 Dependent PGE2 Synthesis and CGRP Release in Rat Trigeminal Ganglia Cells (2011) (121)
- REPRINT: Good Laboratory Practice: Preventing Introduction of Bias at the Bench (2009) (120)
- Body Weight After Stroke: Lessons From the Obesity Paradox (2011) (118)
- The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research* (2020) (117)
- Results of the ICTuS 2 Trial (Intravascular Cooling in the Treatment of Stroke 2) (2016) (117)
- Functional neurological recovery after spinal cord injury is impaired in patients with infections. (2012) (115)
- Ion changes in spreading ischaemia induce rat middle cerebral artery constriction in the absence of NO. (2005) (115)
- Acute pathophysiological processes after ischaemic and traumatic brain injury. (2010) (114)
- Induction of hypoxia inducible factor 1 by oxygen glucose deprivation is attenuated by hypoxic preconditioning in rat cultured neurons (1998) (113)
- SUMO2/3 conjugation is an endogenous neuroprotective mechanism (2011) (111)
- Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase. (2004) (109)
- Noninvasive Assessment of Changes in Cytochrome-c Oxidase Oxidation in Human Subjects during Visual Stimulation (1999) (109)
- Stroke Research Priorities for the Next Decade – A Representative View of the European Scientific Community (2006) (108)
- Effects of cerebral ischemia in mice lacking DNA methyltransferase 1 in post-mitotic neurons (2001) (108)
- Pre- and post-treatment with MK-801 but not pretreatment alone reduces neocortical damage after focal cerebral ischemia in the rat (1990) (108)
- Visualizing Cell Death in Experimental Focal Cerebral Ischemia: Promises, Problems, and Perspectives (2012) (108)
- The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research (2020) (107)
- HMG‐CoA reductase inhibition causes neurite loss by interfering with geranylgeranylpyrophosphate synthesis (2004) (107)
- A Concerted Appeal for International Cooperation in Preclinical Stroke Research (2013) (105)
- Neurotoxicity mechanisms of thioether ecstasy metabolites (2007) (104)
- High prevalence of NMDA receptor IgA/IgM antibodies in different dementia types (2014) (104)
- Anti ICAM-1 (CD 54) monoclonal antibody reduces inflammatory changes in experimental bacterial meningitis (1995) (101)
- Robust research: Institutions must do their part for reproducibility (2015) (100)
- Fighting Publication Bias: Introducing the Negative Results Section (2010) (100)
- Spinal cord injury-induced immunodeficiency is mediated by a sympathetic-neuroendocrine adrenal reflex (2017) (96)
- Olfactory Ensheathing Cell Transplantation in Experimental Spinal Cord Injury: Effect size and Reporting Bias of 62 Experimental Treatments: A Systematic Review and Meta-Analysis (2016) (92)
- International, Multicenter Randomized Preclinical Trials in Translational Stroke Research: It's Time to Act (2012) (92)
- Selective Neuronal Vulnerability Following Mild Focal Brain Ischemia in the Mouse (2003) (91)
- Hyperbaric oxygenation induced tolerance against focal cerebral ischemia in mice is strain dependent (2000) (91)
- Analysis of CO2 vasomotor reactivity and vessel diameter changes by simultaneous venous and arterial Doppler recordings. (1999) (90)
- Pharmacological Uncoupling of Activation Induced Increases in CBF and CMRO2 (2010) (89)
- Where Have All the Rodents Gone? The Effects of Attrition in Experimental Research on Cancer and Stroke (2016) (89)
- Cerebrovascular Vasodilation to Extraluminal Acidosis Occurs via Combined Activation of ATP-Sensitive and Ca2+-Activated Potassium Channels (2003) (88)
- Neurovascular Coupling in Rat Brain Operates Independent of Hemoglobin Deoxygenation (2010) (88)
- Non‐Resolving Aspects of Acute Inflammation after Spinal Cord Injury (SCI): Indices and Resolution Plateau (2011) (86)
- Ischaemia triggered by spreading neuronal activation is inhibited by vasodilators in rats (2001) (84)
- Neuronal gelsolin prevents apoptosis by enhancing actin depolymerization (2004) (84)
- Ischemia and stroke. (2002) (83)
- Near Infrared Spectroscopy in the Diagnosis of Alzheimer's Disease a (1996) (83)
- Nitric Oxide Modulates Spreading Depolarization Threshold in the Human and Rodent Cortex (2008) (82)
- The Gut Microbiome as Therapeutic Target in Central Nervous System Diseases: Implications for Stroke (2016) (82)
- Ischemia triggered by red blood cell products in the subarachnoid space is inhibited by nimodipine administration or moderate volume expansion/hemodilution in rats. (2002) (81)
- Laminar Analysis of Cerebral Blood Flow in Cortex of Rats by Laser-Doppler Flowmetry: A Pilot Study (1997) (80)
- Ecstasy-induced cell death in cortical neuronal cultures is serotonin 2A-receptor-dependent and potentiated under hyperthermia (2006) (80)
- Focoidin, a polysaccharide inhibiting leukocyte rolling, attenuates inflammatory responses in experimental pneumococcal meningitis in rats (1995) (77)
- Effect and reporting bias of RhoA/ROCK-blockade intervention on locomotor recovery after spinal cord injury: a systematic review and meta-analysis. (2014) (76)
- Stroke research at a road block: the streets from adversity should be paved with meta‐analysis and good laboratory practice (2009) (76)
- A fluorescence based non-radioactive electrophoretic mobility shift assay. (2000) (75)
- Increased Extracellular K+ Concentration Reduces the Efficacy of N-methyl-d-aspartate Receptor Antagonists to Block Spreading Depression-Like Depolarizations and Spreading Ischemia (2005) (75)
- In‐vivo confocal scanning laser microscopy of the cerebral microcirculation (1992) (75)
- Distinct Physiologic Properties of Microglia and Blood-Borne Cells in Rat Brain Slices After Permanent Middle Cerebral Artery Occlusion (2000) (74)
- Blockade of Nitric Oxide Synthesis in Rats Strongly Attenuates the CBF Response to Extracellular Acidosis (1993) (72)
- Imaging of leukocytes within the rat brain cortex in vivo. (1991) (72)
- Pathophysiological Interference with Neurovascular Coupling – When Imaging Based on Hemoglobin Might Go Blind (2010) (72)
- Saccadic Suppression Induces Focal Hypooxygenation in the Occipital Cortex (2000) (71)
- Noninvasive near Infrared Spectroscopy Monitoring of Regional Cerebral Blood Oxygenation Changes during Peri-Infarct Depolarizations in Focal Cerebral Ischemia in the Rat (1997) (70)
- Ischemia triggered by spreading neuronal activation is induced by endothelin‐1 and hemoglobin in the subarachnoid space (2003) (70)
- Pneumococcal cell wall components induce nitric oxide synthase and TNF‐α in astroglial‐enriched cultures (1996) (69)
- CGRP Release and c-fos Expression within Trigeminal Nucleus Caudalis of the Rat following Glyceryltrinitrate Infusion (2005) (69)
- Long-term functional outcome in patients with acquired infections after acute spinal cord injury (2017) (69)
- Catabolic Signaling and Muscle Wasting After Acute Ischemic Stroke in Mice: Indication for a Stroke-Specific Sarcopenia (2014) (68)
- Mrp-8 and -14 mediate CNS injury in focal cerebral ischemia. (2009) (68)
- Isoflurane induced prolonged protection against cerebral ischemia in mice: a redox sensitive mechanism? (2002) (66)
- Endothelin-1–Induced Spreading Depression in Rats Is Associated with a Microarea of Selective Neuronal Necrosis (2007) (66)
- Near-infrared fluorescence imaging with fluorescently labeled albumin: A novel method for non-invasive optical imaging of blood–brain barrier impairment after focal cerebral ischemia in mice (2009) (65)
- B-waves in healthy persons. (1989) (65)
- Phosphatidylinositol 3-Akt-Kinase-Dependent Phosphorylation of p21Waf1/Cip1 as a Novel Mechanism of Neuroprotection by Glucocorticoids (2007) (65)
- In Vivo Near-Infrared Fluorescence Imaging of Matrix Metalloproteinase Activity after Cerebral Ischemia (2009) (65)
- Small-molecule-induced Rho-inhibition: NSAIDs after spinal cord injury (2012) (64)
- Global forebrain ischaemia in the rat: controlled reduction of cerebral blood flow by hypobaric hypotension and two-vessel occlusion. (1993) (64)
- CENTRAL NERVOUS SYSTEM INJURYINDUCED IMMUNE DEFICIENCY SYNDROME (2005) (62)
- Cholinergic Pathway Suppresses Pulmonary Innate Immunity Facilitating Pneumonia After Stroke (2015) (62)
- Nitric oxide synthase blockade enhances vasomotion in the cerebral microcirculation of anesthetized rats. (1993) (62)
- Non-invasive visualization of CNS inflammation with nuclear and optical imaging (2009) (61)
- Melatonin is protective in necrotic but not in caspasedependent, free radical‐independent apoptotic neuronal cell death in primary neuronal cultures (2000) (61)
- Nitric oxide: a modulator, but not a mediator, of neurovascular coupling in rat somatosensory cortex. (1999) (61)
- Focal laminar cortical MR signal abnormalities after subarachnoid hemorrhage (2002) (61)
- In Vivo Imaging of the Inflammatory Receptor CD40 After Cerebral Ischemia Using a Fluorescent Antibody (2008) (59)
- Inflammation in stroke: the good, the bad, and the unknown. (2004) (59)
- ET-1 induces cortical spreading depression via activation of the ETA receptor/phospholipase C pathway in vivo. (2004) (59)
- Excessive oxygen or glucose supply does not alter the blood flow response to somatosensory stimulation or spreading depression in rats (1997) (59)
- Bone Marrow-Derived Cells Expressing Green Fluorescent Protein under the Control of the Glial Fibrillary Acidic Protein Promoter Do Not Differentiate into Astrocytes In Vitro and In Vivo (2003) (58)
- Blocking Stroke-Induced Immunodeficiency Increases CNS Antigen-Specific Autoreactivity But Does Not Worsen Functional Outcome after Experimental Stroke (2015) (58)
- Dysexecutive Syndrome After Mild Cerebral Ischemia?: Mice Learn Normally but Have Deficits in Strategy Switching (2003) (58)
- Inhibition of Na+,K+-ATPase activity in cultured rat cerebellar granule cells prevents the onset of apoptosis induced by low potassium (2000) (58)
- Nitric Oxide Modulates the CBF Response to Increased Extracellular Potassium (1995) (57)
- Thomas Willis Lecture: Is Translational Stroke Research Broken, and if So, How Can We Fix It? (2016) (56)
- Protection from brain damage and bacterial infection in murine stroke by the novel caspase-inhibitor Q-VD-OPH (2007) (55)
- Three-Dimensional Reconstruction of the Rat Brain Cortical Microcirculation in vivo (1991) (55)
- Perivascular nerves contribute to cortical spreading depression-associated hyperemia in rats. (1998) (55)
- Simultaneous assessment of cerebral oxygenation and hemodynamics during a motor task. A combined near infrared and transcranial Doppler sonography study. (1997) (55)
- Gut microbiota impact on stroke outcome: Fad or fact? (2016) (54)
- Mitochondrial hexokinase II (HKII) and phosphoprotein enriched in astrocytes (PEA15) form a molecular switch governing cellular fate depending on the metabolic state (2012) (54)
- Immune responses after acute ischemic stroke or myocardial infarction. (2012) (53)
- Tracking of systemically administered mononuclear cells in the ischemic brain by high-field magnetic resonance imaging (2006) (53)
- Separation of changes in light scattering and chromophore concentrations during cortical spreading depression in rats. (1998) (52)
- Systemic Nitric Oxide Synthase Inhibition Does Not Affect Brain Oxygenation during Cortical Spreading Depression in Rats: A Noninvasive Near-Infrared Spectroscopy and Laser-Doppler Flowmetry Study (1996) (52)
- Triptans Reduce the Inflammatory Response in Bacterial Meningitis (2002) (52)
- Cerebral blood oxygenation changes induced by visual stimulation in humans. (1996) (52)
- Membrane attack complex inhibitor CD59a protects against focal cerebral ischemia in mice (2010) (52)
- Noninvasive assessment of cerebral hemodynamics and tissue oxygenation during activation of brain cell function in human adults using near infrared spectroscopy. (1994) (52)
- Vascular Signal Transducer and Activator of Transcription-3 Promotes Angiogenesis and Neuroplasticity Long-Term After Stroke (2015) (51)
- Changing the Mindset in Life Sciences Toward Translation: A Consensus (2014) (50)
- Cerebral oxygenation changes during motor and somatosensory stimulation in humans, as measured by near-infrared spectroscopy. (1996) (50)
- Specific Imaging of Inflammation with the 18kDa Translocator Protein Ligand DPA-714 in Animal Models of Epilepsy and Stroke (2013) (49)
- Glutamate antagonists in therapy of stroke. (1998) (49)
- Confocal laser microscopy to study microcirculation on the rat brain surface in vivo (1989) (49)
- Nitric oxide synthase inhibition does not affect somatosensory evoked potentials in the rat (1996) (49)
- Standard operating procedures (SOP) in experimental stroke research: SOP for middle cerebral artery occlusion in the mouse (2010) (48)
- Improved selective, simple, and contrast staining of acidophilic neurons with vanadium acid fuchsin. (2000) (47)
- Superiority of Preventive Antibiotic Treatment Compared with Standard Treatment of Poststroke Pneumonia in Experimental Stroke: A Bed to Bench Approach (2013) (47)
- Towards Noninvasive Molecular Fluorescence Imaging of the Human Brain (2008) (46)
- Effects of the PDE5-inhibitor vardenafil in a mouse stroke model (2009) (46)
- Neuroprotective effects of the antifungal drug clotrimazole (2002) (46)
- Systematic survey of the design, statistical analysis, and reporting of studies published in the 2008 volume of the Journal of Cerebral Blood Flow and Metabolism (2010) (45)
- Imaging of leukocyte-endothelium interaction using in vivo confocal laser scanning microscopy during the early phase of experimental pneumococcal meningitis. (1993) (45)
- Laser-Doppler measurements of concentration and velocity of moving blood cells in rat cerebral circulation. (1997) (45)
- The worldwide clinical trial research response to the COVID-19 pandemic - the first 100 days. (2020) (43)
- Improving target assessment in biomedical research: the GOT-IT recommendations (2020) (43)
- Rapid Ca2+-dependent NO-production from central nervous system cells in culture measured by NO-nitrite/ozone chemoluminescence (1997) (42)
- Induced Hypothermia in Experimental Pneumococcal Meningitis (2000) (42)
- Atlas registration for edema-corrected MRI lesion volume in mouse stroke models (2017) (42)
- Histone Acetylation and CREB Binding Protein Are Required for Neuronal Resistance against Ischemic Injury (2014) (42)
- Hypothermia for Stroke: Call to Action 2010 (2010) (41)
- Neuronal activity-induced changes of local cerebral microvascular blood oxygenation in the rat: effect of systemic hyperoxia or hypoxia (2003) (41)
- Primary trigeminal afferents are the main source for stimulus-induced CGRP release into jugular vein blood and CSF (2012) (41)
- Heparin Inhibits Leukocyte Rolling in Pial Vessels and Attenuates Inflammatory Changes in a Rat Model of Experimental Bacterial Meningitis (1997) (41)
- Determination of the Brain–Blood Partition Coefficient for Water in Mice Using MRI (2010) (41)
- The neurotoxicity of hallucinogenic amphetamines in primary cultures of hippocampal neurons. (2013) (41)
- 3Rs missing: animal research without scientific value is unethical (2019) (41)
- Evidence of intrathecal immunoglobulin synthesis in stroke: a cohort study. (2012) (40)
- Sulfonylurea Drugs Do Not Influence Initial Stroke Severity and In-Hospital Outcome in Stroke Patients With Diabetes (2001) (40)
- The SCIentinel study - prospective multicenter study to define the spinal cord injury-induced immune depression syndrome (SCI-IDS) - study protocol and interim feasibility data (2013) (40)
- A flow sensitive alternating inversion recovery (FAIR)-MRI protocol to measure hemispheric cerebral blood flow in a mouse stroke model (2008) (39)
- Nitric oxide from perivascular nerves modulates cerebral arterial pH reactivity. (2001) (39)
- CD93/AA4.1: A Novel Regulator of Inflammation in Murine Focal Cerebral Ischemia (2010) (39)
- Doxorubicin induces biphasic neurotoxicity to rat cortical neurons. (2008) (39)
- Age-related changes of oxygen free radical production in the rat brain slice after hypoxia: on-line measurement using enhanced chemiluminescence (1995) (39)
- Visualization of Cell Death in MICE with Focal Cerebral Ischemia using Fluorescent Annexin A5, Propidium Iodide, and Tunel Staining (2011) (39)
- Tumour necrosis factor alpha induces only minor inflammatory changes in the central nervous system, but augments experimental meningitis (1998) (37)
- Vascular Stat3 Promotes Angiogenesis and Neuroplasticity Long-Term After Stroke (2015) (37)
- Human gestational N‐methyl‐d‐aspartate receptor autoantibodies impair neonatal murine brain function (2019) (37)
- Effect of catalase on regional cerebral blood flow and brain edema during the early phase of experimental pneumococcal meningitis. (1992) (36)
- Cortical spreading depression-associated hyperemia in rats: involvement of serotonin (1998) (36)
- Functional imaging with Laser Speckle Contrast Analysis: Vascular compartment analysis and correlation with Laser Doppler Flowmetry and somatosensory evoked potentials (2006) (36)
- Increasing efficiency of preclinical research by group sequential designs (2017) (35)
- Hypothermia effects on neurovascular coupling and cerebral metabolic rate of oxygen (2008) (34)
- Mitochondrial free radical production induced by glucose deprivation in cerebellar granule neurons (2008) (34)
- Protective conditioning of the brain: expressway or roadblock? (2011) (34)
- Rodent Models of Stroke (2016) (34)
- Statistics in Experimental Cerebrovascular Research: Comparison of More than Two Groups with a Continuous Outcome Variable (2010) (34)
- The ischemic cascade and mediators of ischemic injury. (2009) (34)
- Neurovascular coupling during cortical spreading depolarization and -depression. (2015) (34)
- A pocket guide to electronic laboratory notebooks in the academic life sciences (2016) (33)
- Impaired cerebrovascular reactivity after cortical spreading depression in rats: Restoration by nitric oxide or cGMP (2006) (33)
- Vascular change and opposing effects of the angiotensin type 2 receptor in a mouse model of vascular cognitive impairment (2014) (33)
- Systematic review of guidelines for internal validity in the design, conduct and analysis of preclinical biomedical experiments involving laboratory animals (2020) (33)
- Ischemia Triggered by Red Blood Cell Products in the Subarachnoid Space Is Inhibited by Nimodipine Administration or Moderate Volume Expansion/Hemodilution in Rats (2002) (32)
- Role of Nitric Oxide Synthase Inhibition in Leukocyte-Endothelium Interaction in the Rat Pial Microvasculature (1996) (32)
- Results dissemination from clinical trials conducted at German university medical centres was delayed and incomplete. (2019) (31)
- Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3 (2018) (31)
- Methylenetetrahydrofolate reductase deficiency alters levels of glutamate and γ-aminobutyric acid in brain tissue (2015) (30)
- Haemoglobin oxygenation changes during visual stimulation in the occipital cortex. (1997) (30)
- Preregistration of exploratory research: Learning from the golden age of discovery (2020) (30)
- Length of resting period between stimulation cycles modulates hemodynamic response to a motor stimulus. (1997) (29)
- Cerebral ischemia: the microcirculation as trigger and target. (1993) (29)
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- Neuronal activation induced changes in microcirculatory haemoglobin oxygenation: to dip or not to dip (2002) (3)
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- Pathophysiology of Stroke Chair: U Dirnagl (2002) (2)
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- Pathophysiologie der zerebralen Ischämie (1999) (2)
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- Assessing the Organizational Climate for Translational Research with a New Survey Tool (2019) (2)
- Ischämietoleranz Modell für die Forschung, Hoffnung für die Klinik? (2001) (2)
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- PHACTR1 genetic variability is not critical in small vessel ischemic disease patients and PcomA recruitment in C57BL/6J mice (2021) (2)
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- Improving quality of preclinical academic research through auditing: A feasibility study (2020) (2)
- Characterization of the cerebral blood flow response to somatosensory stimulation: the model and the influence of anesthetics (1993) (2)
- Neurotoxicity mechanisms of ecstasy metabolites (2007) (2)
- Increasing discovery rates in preclinical research through optimised statistical decision criteria (2022) (2)
- Reduction of Intracranial Pressure with Anticoagulation in Patients with Venous Sinus Thrombosis (1986) (2)
- Continuous Measurement of Acetazolamide-Stimulated Cerebral Blood Flow by Laser Doppler Flowmetry (1992) (2)
- Endothelin-1 induces cortical spreading depression via activation of the ETA receptor / phospholipase C pathway in vivo (2003) (2)
- Preclinical research: Meet patients to sharpen up research (2017) (2)
- Correction: Individual and temporal variability of the retina after chronic bilateral common carotid artery occlusion (BCCAO) (2018) (2)
- Incorporating equity, diversity, and inclusiveness into the Hong Kong Principles (2021) (2)
- Wisdom of the expert crowd prediction of response for 3 neurology randomized trials (2020) (2)
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- Mechanisms of robust, innovative and translational research (MERIT) (2018) (1)
- Oxygen and the Brain (2000) (1)
- Institutions can retool to make research more rigorous (2020) (1)
- Clinical approaches in near-infrared spectroscopy (1998) (1)
- Errors and Error Management in Biomedical Research (2018) (1)
- Oxford-Berlin Open Research summer school 2019 (2019) (1)
- Is DNA Methylation Deleterious in Cerebral Ischemia (2001) (1)
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- Neuroprotective effects of creatine in a mouse model of stroke: An experimental MRI study (2005) (1)
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- Presentation abstracts (2015) (1)
- Neuroprotective efficacy of valproate in stroke: Replacing preclinical replication experiments by flipping coins? (2017) (1)
- Pathophysiology of Stroke (2006) (1)
- Introducing quality measures in an academic research consortium (2022) (1)
- Measurements of Microcirculatory Events in the Brain in Vivo (1997) (1)
- Depolarization and –Depression Neurovascular Coupling During Cortical Spreading (2015) (1)
- High Precision Measurement of Mean Transit Time for Pharmacological MRI (2000) (1)
- Noninvasive Detection of hemoglobin oxygenation changes during cortical spreading depression in the rat brain (1996) (1)
- Investigation of cortical spreading depression in rats by near infrared spectroscopy: Scattering and oxygenation changes (1998) (1)
- Increased extracellular potassium concentration reduces the efficacy of N-methyl-D-aspartate receptor antagonists to block spreading depression in human and rat brain slices (2005) (1)
- Die MERIT App (2021) (1)
- Therapierelevante Pathophysiologie des akuten ischämischen Schlaganfalls: Was ist gesichert? (2004) (1)
- Kommentare zu R. Spanagel (2021): Replikationskrise in der präklinischen Suchtforschung und Vorschläge zur Krisenbewältigung (2021) (1)
- External validity in translational biomedicine: understanding the conditions enabling the cause to have an effect (2021) (1)
- Paracrine Interleukin 6 Induces Cerebral Remodeling at Early Stages After Unilateral Common Carotid Artery Occlusion in Mice (2022) (1)
- Crossing Borders, Creating Together: An Interdisciplinary Dialogue on Transdisciplinary Knowledge Production (2021) (1)
- Changes of Intracranial Pressure in a Rat Meningitis Model (1989) (1)
- Establishing a core set of open science practices in biomedicine: a modified Delphi study (2022) (1)
- Activation of p21WAF1/CIP1 by erythropoietin prevents neuronal cell death and mediates ischemic preconditioning in primary cortical neurons (2004) (0)
- Pooled data on attrtion in preclinical stroke and cancer (2015) (0)
- Workshops 3, 4: Simulating experimental data (2019) (0)
- Workshop 11: R for Reproducible Scientific Analysis (2019) (0)
- EUROTOXICITY MECHANISMS OF THIOETHER (2007) (0)
- The Journal of Cerebral Blood Flow and Metabolism clinical, inaugural issue (2016) (0)
- Celebrating the 30th Anniversary of our Journal (2012) (0)
- Stroke Patients With Diabetes Sulfonylurea Drugs Do Not Influence Initial Stroke Severity and In-Hospital Outcome in (2001) (0)
- EUSI-ESO News (2008) (0)
- Preclinical research: Meet patients to sharpen up research. (2017) (0)
- The Gut Microbiome as Therapeutic Target in Central Nervous System Diseases: Implications for Stroke (2016) (0)
- Vascular cognitive impairment in the mouse reshapes visual, spatial network functional connectivity (2020) (0)
- A combination of K+ and Endothelin-1 does not Induce Cortical Spreading Ischemia in the Rat (2004) (0)
- Results of the first preclinical multicenter trial: Anti-CD49d treatment in acute brain ischemia (2016) (0)
- Author response: Improving preclinical studies through replications (2020) (0)
- Workshop 18: Open Data and privacy (2019) (0)
- The applicability of laser-Doppler flowmetry for bedside cerebral blood flow measurement in neurological intensive care patients (1993) (0)
- The Physiological Basis of Functional Magnetic Resonance Imaging (1995) (0)
- Workshop 4: Reproducibility crisis in clinical studies? A critical evaluation (2018) (0)
- Mechanisms of vascular reactivity during cortical spreading depression (CSD) and cortical spreading ischemia (CSI) (2005) (0)
- Brain Structural Connectivity Change in a Mouse Model of Vascular Cognitive Impairment (2017) (0)
- Workshop 17: Creative commons licenses (2019) (0)
- Focal cerebral ischemia : A cascade of damage (1999) (0)
- Role of superoxide anion in rat cerebral blood flow response to somatosensory stimulation. (1994) (0)
- Stroke induced immunodepression syndrome (SIDS) (2004) (0)
- Effects of retinoblastoma family members on neuronal apoptosis (2004) (0)
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- Publication Data From Koch Et Al 2017 (2017) (0)
- Monte Carlo Based Correction of Lambert-Beer Algorithm: Early Deoxygenation Changes Measured by Optical Spectroscopy during Whisker Barrel Cortex Activation in Rats (2000) (0)
- Workshop 7: Python kick-off (2019) (0)
- Pebbles as Dry Ice Replacement for Snap Freezing of Rodents Brains (2017) (0)
- Workshop 14: Reproducible neuroimaging (2019) (0)
- QUEST Framework Activities Overview (2019) (0)
- Spatiotemporal correlation of neuronal activity and cerebral blood flow of the motor cortex: Non-invasive measurement of DC-EEG and near-infrared spectroscopy in humans during a motor task (2005) (0)
- neuroRAD 2019 (2019) (0)
- Rotation of Editorial Board Members and new publication formats (2011) (0)
- TREX1 p.A129fs and p.Y305C variants in a large multi-ethnic cohort of CADASIL-like unrelated patients (2022) (0)
- Berlin | Oxford Summer School on Open, Transparent, and Reproducible Research (2018) (0)
- Workshop 9: Reporting your methods and results (2019) (0)
- Workshop 6: Critical appraisal and peer review (2019) (0)
- The microvascular basis of functional magnetic resonance imaging (1995) (0)
- COX-2 expression and CGRP release in primary trigeminal ganglion neurons – implications for the pathophysiology of migraine (2006) (0)
- Quality research needs good working conditions (2023) (0)
- Schadenskaskaden bei der zerebralen Ischämie (2003) (0)
- Das Centrum für Schlaganfallforschung Berlin (CSB) (2009) (0)
- Indikatoren für Open Science: Report des Helmholtz Open Science Forum (2021) (0)
- Krankheitsprozesse im Nervensystem (1995) (0)
- Workshop 10: Tips, traps and other bloopers in preclinical research (2019) (0)
- Modelle ischämischer Schädigungen des Nervensystems (2009) (0)
- Die Bedeutung des intestinalen Mikrobioms beim ischämischen Schlaganfall (2017) (0)
- Cerebrale Nahinfrarotspektroskopie beim Erwachsenen: Ergebnisse bei funktionellen Aktivierungsstudien und Perspektiven für die klinische Anwendung (1997) (0)
- Workshop 2: Planning your publication and dissemination (2019) (0)
- Cortical spreading depression of vascular low-frequency fluctuations in patients with Subarachnoid Haemorrhage (2008) (0)
- Nicht-invasive Messung der zerebralen Hämoglobin-Oxygenierung mit Hilfe der Nah-Infrarot-Spectroskopie (NIRS) bei normalem Altern und bei der Alzheimer Demenz (1996) (0)
- Einrichtung eines Publikationsfonds für die Charité – Universitätsmedizin Berlin und Verstetigung der Finanzierung von Open-Access-Publikationen: DFG-Förderlinie: Wissenschaftliche Literatur- und Informationssysteme, Förderprogramm: Open Access Publizieren, Projektantrag Teil B: Beschreibung des Vor (2019) (0)
- Hoffnung auf Neuroprotektion (2013) (0)
- Bedeutung nicht-neuronaler Zellen bei neurologischen Erkrankungen (1996) (0)
- Regelmäßige körperliche Aktivtität induziert Neo-Vaskularisation, steigert Kapillardichte und zerebralen Blutfluss und schützt vor zerebraler Ischämie (2004) (0)
- Schlaganfallinduzierte Immundepression als Ursache Schlaganfall-assoziierter Infektionen: Die immunologischen Ergebnisse der PANTHERIS-Studie (2006) (0)
- Cerebral Blood Flow and Hemoglobin Oxygenation Changes in Stroke : Fingerprinting with Near Infrared Spectroscopy and MRI (1999) (0)
- Spezifische Bildgebung von Inflammation mit optischer Bildgebung in verschiedenen Tiermodellen (2009) (0)
- Antibakterielle Prävention beim Schlaganfall: Hintergrund, Design und erste Ergebnisse der PANTHERIS-Studie (2005) (0)
- Optische Methoden in der Hirnforschung: Der Einsatz von Licht zur Untersuchung des Gehirnes (1995) (0)
- Präventive antiinfektive Therapie nach akutem Schlaganfall: Die klinischen Ergebnisse der PANTHERIS-Studie (2006) (0)
- Schlaganfall: Inflammation, Immundepression, Infektion (2009) (0)
- Normale und inverse neurovaskuläre Kopplung und Suppression der niederfrequenten vaskulären Fluktuationen während Cortical Spreading Depolarisations im menschlichen Hirn (2008) (0)
- Präventive ANtibakterielle THERapie beim akuten ischämischen Schlaganfall – PANTHERIS-Studie (2004) (0)
- Prävention schlaganfallassoziierter Infektionen und immunologische Rekonstitution durch den nicht-toxischen Caspaseinihibtor Q-VD-OPh im Mausmodell (2006) (0)
- Long-Term Connectome Analysis Reveals Reshaping of Visual, Spatial Networks in a Model With Vascular Dementia Features (2022) (0)
- Workshop 20: Jupyter notebooks and Python visualisation (2019) (0)
- The N-methyl-D-aspartate receptor (NMDAR) antagonist MK-801 does not block spreading ischemia in the rat (2005) (0)
- Workshop 12: Adding to the global web of knowledge: Wikipedia, Wikidata and open platforms (2019) (0)
- Planning preclinical confirmatory multicenter trials to strengthen translation from basic to clinical research – a multi-stakeholder workshop report (2022) (0)
- Hallucinogenic amphetamines neurotoxicity in cultured hippocampal neurons (2011) (0)
- Workshop 15: Working with sensitive research data (2019) (0)
- Thomas Willis Lecture (2016) (0)
- Ischemic preconditioning and tolerance in human brain [6] (multiple letters) (2000) (0)
- Balancing sensitivity and specificity in preclinical research (2022) (0)
- Mapping of cerebral oxygenation changes during performance of a motor task: a multisite near infrared spectroscopy study (1996) (0)
- P.5.088 Toxicity of excitatory amino acids in organotypic retinal cultures of postnatal and adult rats (2005) (0)
- International Graduate Program ‘Medical Neurosciences’ an der Charite Berlin (2002) (0)
- Statistics in Experimental Stroke Research: From Sample Size Calculation to Data Description and Significance Testing (2010) (0)
- Workshop 16: Reproducible workflows (2018) (0)
- Assessing the Organizational Climate for Translational Research with a New Survey Tool (2020) (0)
- Lecture: Open Access (2018) (0)
- Agents for preventive therapy after acute stroke. (2002) (0)
- Improving quality of preclinical academic research through auditing: (2020) (0)
- Modeling Immunity and Inflammation in Stroke (2014) (0)
- Ability of patients with acute ischemic stroke to recall given information on intravenous thrombolysis: Results of a prospective multicenter study (2023) (0)
- 52. Cortical spreading depression of vascular low-frequency fluctuations in patients with subarachnoid haemorrhage (2009) (0)
- Panel: Restoring Trust in Published Research (2021) (0)
- Benchmarking university medical centres for responsible metrics (2018) (0)
- Old Dogmas, Surprising Complexities, and Novel Therapeutic Targets (2014) (0)
- Workshop 8: Managing research data and data management plans (2019) (0)
- Health tips for research groups (2018) (0)
- Workshop 5: Replication (2019) (0)
- THE EQIPD FRAMEWORK FOR RIGOUR IN THE DESIGN, CONDUCT AND ANALYSIS OF BIOMEDICAL EXPERIMENTS (2019) (0)
- Unique properties of PTEN-L contribute to neuroprotection in response to ischemic-like stress (2019) (0)
- Workshop 1: Introduction to R (2019) (0)
- The Johann Jacob Wepfer Award 2013 (2013) (0)
- Results dissemination from clinical trials conducted at German university medical centres was delayed and incomplete (2018) (0)
- Explorer Olfactory Ensheathing Cell Transplantation in Experimental Spinal Cord Injury (2016) (0)
- Workshop 1: Statistics refresher (2018) (0)
- Information about attrtion in preclinical stroke studies from CAMARADES database (2015) (0)
- Prediction of Stroke Outcome in Mice Based on Non-Invasive MRI and Behavioral Testing (2022) (0)
- Endogenous Protection Against Hypoxia/ Ischemia in the Brain via Erythropoietin (2004) (0)
- A new home for the Journal of Cerebral Blood Flow and Metabolism (2016) (0)
- Workshop 13: How to write your first pre-registration (2019) (0)
- Workshop 8: Public Engagement in Research and Debate (2018) (0)
- BIH survey on organizational research climate and translation (2018) (0)
- Vascular Stat3 Promotes Angiogenesis and Neuroplasticity (2015) (0)
- Magnetic resoncance and optical imaging of stroke induced brain inflammation (2005) (0)
- 2015 in ten cartoons (2015) (0)
- Natural Killer (NK) Cell Functionality after human Spinal Cord Injury (SCI) (2016) (0)
- Workshop 3: Critical appraisal and peer review (2018) (0)
- Perfusion-related changes in the temporal dynamics of the blood-oxygen-level-dependent signal in a mouse model of focal cerebral ischemia (2017) (0)
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What Schools Are Affiliated With Ulrich Dirnagl?
Ulrich Dirnagl is affiliated with the following schools: