Ulrich Hübscher
#143,631
Most Influential Person Now
Ulrich Hübscher's AcademicInfluence.com Rankings
Ulrich Hübscherbiology Degrees
Biology
#10296
World Rank
#13611
Historical Rank
Cell Biology
#481
World Rank
#493
Historical Rank
Molecular Biology
#1488
World Rank
#1515
Historical Rank
Biochemistry
#1621
World Rank
#1754
Historical Rank
Download Badge
Biology
Ulrich Hübscher's Degrees
- PhD Biochemistry University of Zurich
- Masters Biochemistry University of Zurich
Why Is Ulrich Hübscher Influential?
(Suggest an Edit or Addition)Ulrich Hübscher's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Proliferating cell nuclear antigen (PCNA): a dancer with many partners (2003) (1054)
- Mammalian DNA nucleotide excision repair reconstituted with purified protein components (1995) (849)
- Efficient production of chicken egg yolk antibodies against a conserved mammalian protein (1990) (373)
- Nucleotide excision repair of DNA with recombinant human proteins: definition of the minimal set of factors, active forms of TFIIH, and modulation by CAK. (2000) (334)
- A CAF-1–PCNA-Mediated Chromatin Assembly Pathway Triggered by Sensing DNA Damage (2000) (326)
- Mammalian Base Excision Repair: the Forgotten Archangel (2013) (303)
- Nucleotide excision repair DNA synthesis by DNA polymerase epsilon in the presence of PCNA, RFC, and RPA. (1995) (294)
- Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine. (2010) (275)
- Proliferating cell nuclear antigen: More than a clamp for DNA polymerases (1997) (254)
- Regulation of DNA replication and repair proteins through interaction with the front side of proliferating cell nuclear antigen (1998) (247)
- The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks (2011) (245)
- The 3′–5′ exonucleases (2002) (239)
- 8-oxo-guanine bypass by human DNA polymerases in the presence of auxiliary proteins (2007) (232)
- Deinococcus radiodurans: What Belongs to the Survival Kit? (2008) (226)
- Eukaryotic DNA polymerases, a growing family. (2000) (209)
- Double‐check probing of DNA bending and unwinding by XPA–RPA: an architectural function in DNA repair (2001) (186)
- Mammalian base excision repair by DNA polymerases δ and ε (1998) (178)
- Regulation of human flap endonuclease-1 activity by acetylation through the transcriptional coactivator p300. (2001) (177)
- Arginine Methylation Regulates DNA Polymerase β (2006) (156)
- Clamping down on clamps and clamp loaders--the eukaryotic replication factor C. (1998) (138)
- Detection of the catalytic activities of DNA polymerases and their associated exonucleases following SDS-polyacrylamide gel electrophoresis. (1981) (137)
- Mechanism of inhibition of proliferating cell nuclear antigen-dependent DNA synthesis by the cyclin-dependent kinase inhibitor p21. (1995) (135)
- The human Rad9/Rad1/Hus1 damage sensor clamp interacts with DNA polymerase beta and increases its DNA substrate utilisation efficiency: implications for DNA repair. (2004) (133)
- Okazaki fragment processing: Modulation of the strand displacement activity of DNA polymerase δ by the concerted action of replication protein A, proliferating cell nuclear antigen, and flap endonuclease-1 (2001) (128)
- A mammalian protein complex that repairs double-strand breaks and deletions by recombination. (1993) (125)
- An 8-oxo-guanine repair pathway coordinated by MUTYH glycosylase and DNA polymerase λ (2009) (124)
- Phosphorylation of human Fen1 by cyclin-dependent kinase modulates its role in replication fork regulation (2003) (121)
- Functional roles of DNA polymerases beta and gamma. (1979) (119)
- A Direct Interaction between Proliferating Cell Nuclear Antigen (PCNA) and Cdk2 Targets PCNA-interacting Proteins for Phosphorylation* (2000) (118)
- Glyceraldehyde‐3‐Phosphate Dehydrogenase Is a Nonhistone Protein and a Possible Activator of Transcription in Neurons (1986) (111)
- Clamping down on clamps and clamp loaders (1998) (109)
- DNA polymerase beta bypasses in vitro a single d(GpG)-cisplatin adduct placed on codon 13 of the HRAS gene. (1995) (109)
- Arginine methylation regulates DNA polymerase beta. (2006) (109)
- Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus. (1991) (108)
- Mammalian DNA polymerase auxiliary proteins: analysis of replication factor C-catalyzed proliferating cell nuclear antigen loading onto circular double-stranded DNA (1995) (105)
- Mediation of Proliferating Cell Nuclear Antigen (PCNA)-dependent DNA Replication through a Conserved p21Cip1-like PCNA-binding Motif Present in the Third Subunit of Human DNA Polymerase δ* (2001) (103)
- Human DNA Polymerase λ Functionally and Physically Interacts with Proliferating Cell Nuclear Antigen in Normal and Translesion DNA Synthesis* (2002) (99)
- Reconstitution of the base excision repair pathway for 7,8-dihydro-8-oxoguanine with purified human proteins. (2002) (99)
- Mammalian base excision repair by DNA polymerases delta and epsilon. (1998) (98)
- The hyperthermophilic euryarchaeota Pyrococcus abyssi likely requires the two DNA polymerases D and B for DNA replication. (2005) (98)
- A conserved domain of the large subunit of replication factor C binds PCNA and acts like a dominant negative inhibitor of DNA replication in mammalian cells. (1996) (94)
- Resistance to nevirapine of HIV-1 reverse transcriptase mutants: loss of stabilizing interactions and thermodynamic or steric barriers are induced by different single amino acid substitutions. (1997) (93)
- Incorporation of reporter molecule-labeled nucleotides by DNA polymerases. II. High-density labeling of natural DNA. (2003) (92)
- DNA polymerase delta, an essential enzyme for DNA transactions. (1997) (91)
- Humoral immune reactivity to feline leukemia virus and associated antigens in cats naturally infected with feline leukemia virus. (1980) (88)
- Revised nomenclature for eukaryotic DNA polymerases. (1990) (87)
- The DNA-polymerase-X family: controllers of DNA quality? (2004) (87)
- Recognition by viral and cellular DNA polymerases of nucleosides bearing bases with nonstandard hydrogen bonding patterns. (1995) (86)
- The two DNA clamps Rad9/Rad1/Hus1 complex and proliferating cell nuclear antigen differentially regulate flap endonuclease 1 activity. (2005) (85)
- Variation of DNA polymerases - α , - β . and - γ during perinatal tissue growth and differentiation (1977) (84)
- DNA Polymerase β from Brain Neurons Is a Repair Enzyme (1979) (84)
- The human checkpoint sensor and alternative DNA clamp Rad9-Rad1-Hus1 modulates the activity of DNA ligase I, a component of the long-patch base excision repair machinery. (2005) (82)
- DNA unwinding activity of replication protein A (1992) (82)
- Resistance of human nucleotide excision repair synthesis in vitro to p21Cdn1 (1998) (79)
- Human DNA polymerase lambda possesses terminal deoxyribonucleotidyl transferase activity and can elongate RNA primers: implications for novel functions. (2003) (79)
- Lagging strand DNA synthesis by calf thymus DNA polymerases α, β, δ and ε in the presence of auxiliary proteins (1993) (79)
- Regulation of oxidative DNA damage repair by DNA polymerase λ and MutYH by cross-talk of phosphorylation and ubiquitination (2011) (77)
- DNA polymerase switching: I. Replication factor C displaces DNA polymerase α prior to PCNA loading (2000) (76)
- Involvement of an X family DNA polymerase in double‐stranded break repair in the radioresistant organism Deinococcus radiodurans (2004) (73)
- Flap endonuclease 1: a novel tumour suppresser protein. (2003) (73)
- Calf thymus RF-C as an essential component for DNA polymerase δ and ε holoenzymes function (1992) (73)
- Methylation of DNA polymerase ß by protein arginine methyltransferase 1 regulates its binding to proliferating cell nuclear antigen (2007) (73)
- De novo DNA synthesis by human DNA polymerase lambda, DNA polymerase mu and terminal deoxyribonucleotidyl transferase. (2004) (73)
- The checkpoint clamp, Rad9-Rad1-Hus1 complex, preferentially stimulates the activity of apurinic/apyrimidinic endonuclease 1 and DNA polymerase β in long patch base excision repair (2007) (72)
- Replication protein A and proliferating cell nuclear antigen coordinate DNA polymerase selection in 8-oxo-guanine repair (2008) (71)
- Human DNA polymerase lambda diverged in evolution from DNA polymerase beta toward specific Mn(++) dependence: a kinetic and thermodynamic study. (2003) (70)
- Identity of DNA polymerase gamma from synaptosomal mitochondria and rat-brain nuclei. (1977) (70)
- DNA polymerase switching: II. Replication factor C abrogates primer synthesis by DNA polymerase alpha at a critical length. (2000) (68)
- MUTYH DNA glycosylase: the rationale for removing undamaged bases from the DNA (2013) (66)
- DNA replication and repair bypass machines. (2011) (66)
- Replication of the lagging strand: a concert of at least 23 polypeptides. (2001) (66)
- A DNA ligase from the psychrophile Pseudoalteromonas haloplanktis gives insights into the adaptation of proteins to low temperatures. (2000) (65)
- Human DNA polymerases lambda and beta show different efficiencies of translesion DNA synthesis past abasic sites and alternative mechanisms for frameshift generation. (2004) (64)
- The solution structure of functionally active human proliferating cell nuclear antigen determined by small-angle neutron scattering. (1998) (63)
- The large subunit of HIV-1 reverse transcriptase interacts with beta-actin. (1995) (62)
- Tyrosine 114 is essential for the trimeric structure and the functional activities of human proliferating cell nuclear antigen. (1995) (62)
- Replication Protein A as a “Fidelity Clamp” for DNA Polymerase α* (2001) (61)
- Specificity assessment of feline T-lymphotropic lentivirus serology. (1988) (61)
- Microhomology-mediated DNA strand annealing and elongation by human DNA polymerases λ and β on normal and repetitive DNA sequences (2012) (61)
- The human GINS complex binds to and specifically stimulates human DNA polymerase α‐primase (2007) (60)
- The acetylatable lysines of human Fen1 are important for endo- and exonuclease activities. (2003) (59)
- Differential discrimination of DNA polymerase for variants of the non-standard nucleobase pair between xanthosine and 2,4-diaminopyrimidine, two components of an expanded genetic alphabet. (1996) (57)
- DNA Polymerase λ from Calf Thymus Preferentially Replicates Damaged DNA* (2002) (57)
- A novel proteomic approach identifies new interaction partners for proliferating cell nuclear antigen. (2007) (56)
- Cell cycle‐dependent dynamic association of cyclin/Cdk complexes with human DNA replication proteins (2002) (56)
- The interaction site of Flap Endonuclease-1 with WRN helicase suggests a coordination of WRN and PCNA (2005) (55)
- DNA polymerase delta holoenzyme: action on single-stranded DNA and on double-stranded DNA in the presence of replicative DNA helicases. (1995) (54)
- DNA Polymerases: Discovery, Characterization and Functions in Cellular DNA Transactions (2010) (54)
- DNA polymerase switching: I. Replication factor C displaces DNA polymerase alpha prior to PCNA loading. (2000) (51)
- Eukaryotic DNA replication. Enzymes and proteins acting at the fork. (1990) (51)
- The mammalian primase is part of a high molecular weight DNA polymerase alpha polypeptide. (1983) (50)
- Control of DNA polymerase λ stability by phosphorylation and ubiquitination during the cell cycle (2008) (50)
- In Eukaryotic Flap Endonuclease 1, the C Terminus Is Essential for Substrate Binding* (2001) (50)
- Assembly of DNA polymerase 6 and e holoenzymes depends on the geometry of the DNA template (1994) (50)
- The delta subunit of Escherichia coli DNA polymerase III holoenzyme is the dnaX gene product. (1979) (49)
- Modulation of Cellular Response to Cisplatin by a Novel Inhibitor of DNA Polymerase β (2005) (49)
- Phosphorylation of human DNA polymerase λ by the cyclin-dependent kinase Cdk2/cyclin A complex is modulated by its association with proliferating cell nuclear antigen (2005) (49)
- Strand displacement activity of the human immunodeficiency virus type 1 reverse transcriptase heterodimer and its individual subunits. (1994) (49)
- Mammalian DNA polymerase alpha holoenzymes with possible functions at the leading and lagging strand of the replication fork. (1984) (48)
- Human Immunodeficiency Virus type 1 reverse transcriptase. (1996) (47)
- The flexible loop of human FEN1 endonuclease is required for flap cleavage during DNA replication and repair (2002) (47)
- Novel histone H2A-like protein of escherichia coli. (1980) (46)
- Calf thymus DNA polymerase δ Independent of proliferating cell nuclear antigen (PCNA) (1989) (46)
- Multiple roles for kinases in DNA replication (2003) (45)
- Activity profiles of enzymes that control the uracil incorporation into DNA during neuronal development. (1990) (45)
- Inhibition of mammalian DNA polymerases by resveratrol: mechanism and structural determinants. (2005) (45)
- DNA replication machinery: functional characterization of a complex containing DNA polymerase alpha, DNA polymerase delta, and replication factor C suggests an asymmetric DNA polymerase dimer. (1996) (45)
- Recovery of functional proteins in sodium dodecyl sulfate gels. (1983) (44)
- Sites of termination of in vitro DNA synthesis on cis-diamminedichloroplatinum(II) treated single-stranded DNA: a comparison between E. coli DNA polymerase I and eucaryotic DNA polymerases alpha. (1988) (44)
- DNA fingerprinting: improved DNA extraction from small blood samples. (1988) (44)
- Regulation of oxidative DNA damage repair: The adenine:8-oxo-guanine problem (2012) (44)
- DNA polymerase epsilon interacts with proliferating cell nuclear antigen in primer recognition and elongation. (1995) (43)
- Generation of a Mono‐ubiquitinated PCNA Mimic by Click Chemistry (2011) (43)
- DNA unwinding by replication protein A is a property of the 70 kDa subunit and is facilitated by phosphorylation of the 32 kDa subunit. (1993) (42)
- Four different DNA helicases from calf thymus. (1992) (42)
- A coordinated interplay: proteins with multiple functions in DNA replication, DNA repair, cell cycle/checkpoint control, and transcription. (2001) (41)
- Germ Line Transformation of Mammals by Pronuclear Microinjection (2000) (40)
- Inhibitor analysis of calf thymus DNA polymerases α, δ and ϵ (1994) (40)
- The Fen1 extrahelical 3'-flap pocket is conserved from archaea to human and regulates DNA substrate specificity. (2004) (40)
- Proteins Involved in DNA Replication (1984) (38)
- DNA polymerase δ-interacting protein 2 is a processivity factor for DNA polymerase λ during 8-oxo-7,8-dihydroguanine bypass (2013) (38)
- DNA polymerase θ purified from human cells is a high-fidelity enzyme (2002) (37)
- Evidence that a high molecular weight replicative DNA polymerase is conserved during evolution. (1981) (37)
- Error-free bypass of 2-hydroxyadenine by human DNA polymerase λ with Proliferating Cell Nuclear Antigen and Replication Protein A in different sequence contexts (2007) (36)
- Colocalization of human Rad17 and PCNA in late S phase of the cell cycle upon replication block (2002) (35)
- Feline immunodeficiency virus reverse transcriptase: expression, functional characterization, and reconstitution of the 66- and 51-kilodalton subunits (1995) (35)
- DNA polymerase X from Deinococcus radiodurans possesses a structure‐modulated 3′→5′ exonuclease activity involved in radioresistance (2006) (34)
- Impact of ribonucleotide incorporation by DNA polymerases β and λ on oxidative base excision repair (2016) (34)
- Origin of adeno-associated virus DNA replication is a target of carcinogen-inducible DNA amplification (1991) (33)
- The human GINS complex binds to and specifically stimulates human DNA polymerase alpha-primase. (2007) (33)
- Silencing of human DNA polymerase λ causes replication stress and is synthetically lethal with an impaired S phase checkpoint (2012) (33)
- Extra DNA in forebrain cortical neurons. (1978) (33)
- A switch between DNA polymerases δ and λ promotes error-free bypass of 8-oxo-G lesions (2012) (33)
- Chimeric HIV-1 and feline immunodeficiency virus reverse transcriptases: critical role of the p51 subunit in the structural integrity of heterodimeric lentiviral DNA polymerases. (1998) (33)
- Calf thymus DNA polymerase delta: purification, biochemical and functional properties of the enzyme after its separation from DNA polymerase alpha, a DNA dependent ATPase and proliferating cell nuclear antigen. (1988) (32)
- DNA replication and chemotherapy. (1994) (32)
- Mammalian DNA helicase. (1985) (32)
- DNA Elongation by the Human DNA Polymerase λ Polymerase and Terminal Transferase Activities Are Differentially Coordinated by Proliferating Cell Nuclear Antigen and Replication Protein A* (2005) (32)
- Do DNA polymerases δ and α act coordinately as leading and lagging strand replicases? (1988) (32)
- Phosphorylation of the PCNA binding domain of the large subunit of replication factor C by Ca2+/calmodulin-dependent protein kinase II inhibits DNA synthesis. (1997) (32)
- Genotype-phenotype analysis of S326C OGG1 polymorphism: a risk factor for oxidative pathologies. (2013) (31)
- 17 DNA Replication Accessory Proteins (1996) (31)
- A unified nomenclature for the subunits of eukaryotic DNA polymerase delta. (2001) (31)
- Replication factor C from the hyperthermophilic archaeon Pyrococcus abyssi does not need ATP hydrolysis for clamp-loading and contains a functionally conserved RFC PCNA-binding domain. (2002) (31)
- Proteomic analysis of p16ink4a‐binding proteins (2007) (31)
- DNA polymerase ε: in search of a function (1992) (30)
- DNA polymerase beta can incorporate ribonucleotides during DNA synthesis of undamaged and CPD-damaged DNA. (2003) (30)
- Dual mode of interaction of DNA polymerase epsilon with proliferating cell nuclear antigen in primer binding and DNA synthesis. (1999) (30)
- The human DNA polymerase λ interacts with PCNA through a domain important for DNA primer binding and the interaction is inhibited by p21/WAF1/CIP1 (2004) (29)
- Nevirapine-selected mutations Y181I/C of HIV-1 reverse transcriptase confer cross-resistance to stavudine (2003) (29)
- The Bloom's syndrome helicase (BLM) interacts physically and functionally with p12, the smallest subunit of human DNA polymerase δ (2008) (29)
- Regulation of the DNA replication fork: a way to fight genomic instability (2004) (29)
- Cloning of a mouse cDNA encoding DNA polymerase δ : refinement of the homology boxes (1993) (29)
- Mutagenesis of human DNA polymerase lambda: essential roles of Tyr505 and Phe506 for both DNA polymerase and terminal transferase activities. (2003) (28)
- Ultrastructural cryoimmunocytochemistry is a convenient tool for the study of DNA replication in cultured cells. (1991) (28)
- Repair and translesion DNA polymerases as anticancer drug targets. (2008) (28)
- Ribonucleotide incorporation by human DNA polymerase η impacts translesion synthesis and RNase H2 activity (2016) (28)
- DNA replication fork proteins. (2009) (27)
- The Block of DNA Polymerase δ Strand Displacement Activity by an Abasic Site Can Be Rescued by the Concerted Action of DNA Polymerase β and Flap Endonuclease 1 (2009) (27)
- Functions of DNA Polymerases α, β, and γ in Neurons during Development (1979) (27)
- DNA Ligase I Selectively Affects DNA Synthesis by DNA Polymerases δ and ε Suggesting Differential Functions in DNA Replication and Repair* (1998) (27)
- Structural homology among calf thymus alpha-polymerase polypeptides. (1982) (27)
- Activation of DNA Replication in Yeast by Recruitment of the RNA Polymerase II Transcription Complex (1999) (26)
- Mammalian DNA polymerase α: a replication competent holoenzyme form from calf thymus (1987) (26)
- Human replication protein A can suppress the intrinsic in vitro mutator phenotype of human DNA polymerase λ (2006) (26)
- Lagging strand DNA synthesis by calf thymus DNA polymerases alpha, beta, delta and epsilon in the presence of auxiliary proteins. (1993) (26)
- The Family X DNA Polymerase from Deinococcus radiodurans Adopts a Non-standard Extended Conformation (2009) (26)
- Involvement of Werner syndrome protein in MUTYH-mediated repair of oxidative DNA damage (2012) (25)
- DNA methyltransferases: activity minigel analysis and determination with DNA covalently bound to a solid matrix. (1985) (25)
- Nevirapine Resistance Mutation at Codon 181 of the HIV-1 Reverse Transcriptase Confers Stavudine Resistance by Increasing Nucleotide Substrate Discrimination and Phosphorolytic Activity* (2003) (25)
- DNA polymerase theta purified from human cells is a high-fidelity enzyme. (2002) (24)
- Regulation of Human MutYH DNA Glycosylase by the E3 Ubiquitin Ligase Mule (2014) (24)
- The dnaZ protein, the gamma subunit of DNA polymerase III holoenzyme of Escherichia coli. (1980) (24)
- DNA polymerase lambda from calf thymus preferentially replicates damaged DNA. (2002) (23)
- Inhibitor analysis of calf thymus DNA polymerases alpha, delta and epsilon. (1994) (22)
- Expanding the repertoire of DNA polymerase substrates: template-instructed incorporation of non-nucleoside triphosphate analogues by DNA polymerases β and λ (2006) (22)
- Production of active mouse DNA polymerase β in bacteria (1995) (22)
- Newly synthesized l-enantiomers of 3'-fluoro-modified β-2'-deoxyribonucleoside 5'-triphosphates inhibit hepatitis B DNA polymerases but not the five cellular DNA polymerases α, β, γ, δ, and ε nor HIV-1 reverse transcriptase (1998) (21)
- A mammalian DNA polymerase alpha holoenzyme functioning on defined in vivo‐like templates. (1982) (21)
- Intramolecular chimeras of the p51 subunit between HIV-1 and FIV reverse transcriptases suggest a stabilizing function for the p66 subunit in the heterodimeric enzyme. (1999) (21)
- The PCNA from Thermococcus fumicolans functionally interacts with DNA polymerase delta. (2000) (20)
- High Potency of Indolyl Aryl Sulfone Nonnucleoside Inhibitors towards Drug-Resistant Human Immunodeficiency Virus Type 1 Reverse Transcriptase Mutants Is Due to Selective Targeting of Different Mechanistic Forms of the Enzyme (2005) (20)
- DNA helicase from calf thymus. Purification to apparent homogeneity and biochemical characterization of the enzyme. (1990) (20)
- Agnoprotein of polyomavirus BK interacts with proliferating cell nuclear antigen and inhibits DNA replication (2015) (20)
- Double replica southwestern. (1987) (20)
- Eukaryotic DNA helicases (1990) (20)
- Calf thymus DNA helicase F, a replication protein A copurifying enzyme. (1994) (19)
- Discovery of non-nucleoside inhibitors of HIV-1 reverse transcriptase competing with the nucleotide substrate. (2007) (19)
- Calf thymus RF-C as an essential component for DNA polymerase delta and epsilon holoenzymes function. (1992) (18)
- Slow‐, Tight‐Binding HIV‐1 Reverse Transcriptase Non‐Nucleoside Inhibitors Highly Active against Drug‐Resistant Mutants (2007) (17)
- Betalactam antibiotics interfere with eukaryotic DNA-replication by inhibiting DNA polymerase alpha. (1987) (17)
- DNA polymerase holoenzymes (1984) (17)
- DNA synthesis enzymes and proliferating cell nuclear antigen in normal and neoplastic nerve cells. (1992) (16)
- Calcium-dependent calmodulin-binding proteins associated with mammalian DNA polymerases α (1988) (16)
- A new proofreading mechanism for lesion bypass by DNA polymerase‐λ (2012) (16)
- Ubiquitylation of DNA polymerase λ (2011) (15)
- The Human Tim-Tipin Complex Interacts Directly with DNA Polymerase ϵ and Stimulates Its Synthetic Activity* (2013) (15)
- Molecular basis for the enantioselectivity of HIV-1 reverse transcriptase: role of the 3'-hydroxyl group of the L-(beta)-ribose in chiral discrimination between D- and L-enantiomers of deoxy- and dideoxy-nucleoside triphosphate analogs. (1999) (14)
- Potentiation of Inhibition of Wild-Type and Mutant Human Immunodeficiency Virus Type 1 Reverse Transcriptases by Combinations of Nonnucleoside Inhibitors and d- and l-(β)-Dideoxynucleoside Triphosphate Analogs (2001) (14)
- DNA polymerase beta from brain neurons is a repair enzyme. (1979) (14)
- Diketo Hexenoic Acid Derivatives Are Novel Selective Non-Nucleoside Inhibitors of Mammalian Terminal Deoxynucleotidyl Transferases, with Potent Cytotoxic Effect against Leukemic Cells (2005) (13)
- A double-loop model for the replication of eukaryotic DNA. (1989) (13)
- Probing interactions between HIV-1 reverse transcriptase and its DNA substrate with backbone-modified nucleotides. (1999) (13)
- Incorporation of non-nucleoside triphosphate analogues opposite to an abasic site by human DNA polymerases β and λ (2005) (13)
- Enzyme studies of phi X174 DNA replication. (1981) (13)
- Replication of single-stranded porcine circovirus DNA by DNA polymerases alpha and delta. (1988) (12)
- Regulation of DNA metabolic enzymes upon induction of preB cell development and V(D)J recombination: up-regulation of DNA polymerase delta. (1997) (12)
- Electron microscopic analysis reveals that replication factor C is sequestered by single-stranded DNA. (1999) (11)
- Assembly of DNA polymerase delta and epsilon holoenzymes depends on the geometry of the DNA template. (1994) (11)
- DNA polymerases: Biology, diseases and biomedical applications. (2015) (11)
- DNA polymerases in prokaryotes and eukaryotes: Mode of action and biological implications (1983) (11)
- Review: Eukaryotic DNA helicases: Essential enzymes for DNA transactions (1992) (11)
- Chromatin changes accompanying neuronal differentiation. (1983) (11)
- Current understanding of UV-induced base pair substitution mutation in E. coli with particular reference to the DNA polymerase III complex. (1987) (11)
- HIV-1 nucleocapsid protein and replication protein A influence the strand displacement DNA synthesis of lentiviral reverse transcriptase. (1997) (10)
- Expansion of CAG triplet repeats by human DNA polymerases λ and β in vitro, is regulated by flap endonuclease 1 and DNA ligase 1. (2015) (10)
- Functional Genomics in HIV-1 Virus Replication: Protein-Protein Interactions as a Basis for Recruiting the Host Cell Machinery for Viral Propagation (2001) (10)
- Effects of beta-lactams on DNA replication (1986) (10)
- Living on the Edge: DNA Polymerase Lambda between Genome Stability and Mutagenesis. (2017) (10)
- 4'-Acylated thymidine 5'-triphosphates: a tool to increase selectivity towards HIV-1 reverse transcriptase. (1998) (9)
- Developmental activity profile of DNA polymerases delta and alpha in rat neurons suggests a coordinated in vivo function. (1988) (9)
- Mammalian DNA polymerase alpha: a replication-competent holoenzyme form from calf thymus. (1987) (8)
- The N-terminal region of DNA polymerase δ catalytic subunit is necessary for holoenzyme function (2000) (8)
- [Quantification of proviral FIV DNA using competitive PCR]. (1996) (8)
- Cloning, chromosomal localization, and interspecies interaction of mouse DNA polymerase delta small subunit (PolD2). (1997) (8)
- The p15 carboxyl-terminal proteolysis product of the human immunodeficiency virus type 1 reverse transcriptase p66 has DNA polymerase activity. (1991) (7)
- Quantitation with monoclonal antibodies of Escherichia coli H protein suggests histone function (1985) (7)
- Drug Resistance Mutations in the Nucleotide Binding Pocket of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Differentially Affect the Phosphorolysis-Dependent Primer Unblocking Activity in the Presence of Stavudine and Zidovudine and Its Inhibition by Efavirenz (2005) (7)
- Interaction of cis-diamminedichloroplatinum (II) with single-stranded DNA in the presence or absence of Escherichia coli single-stranded binding protein. (1991) (7)
- Year : 2005 Incorporation of non-nucleoside triphosphate analogues opposite to an abasic site by human DNA polymerases beta and lambda (2006) (6)
- The N-terminal region of DNA polymerase delta catalytic subunit is necessary for holoenzyme function. (2000) (6)
- [The chicken egg as a supply of polyclonal antibodies]. (1990) (6)
- Human DNA polymerase β, but not λ, can bypass a 2-deoxyribonolactone lesion together with proliferating cell nuclear antigen. (2013) (6)
- DNA elongation by the human DNA polymerase lambda polymerase and terminal transferase activities are differentially coordinated by proliferating cell nuclear antigen and replication (2006) (6)
- DNA polymerases and diseases (2005) (6)
- [Is health really the most important value? - Results of a representative survey of the German general population concerning the subjective meaning of health]. (2010) (5)
- Variation of DNA polymerases-alpha, -beta. and -gamma during perinatal tissue growth and differentiation. (1977) (5)
- Calf thymus DNA polymerase delta independent of proliferating cell nuclear antigen (PCNA). (1989) (5)
- Mammalian DNA Polymerase α Holoenzyme (1984) (5)
- Calcium-dependent calmodulin-binding proteins associated with mammalian DNA polymerase alpha. (1988) (5)
- DNA Polymerases in the Three Kingdoms of Life: Bacteria, Archaea and Eukaryotes (2010) (5)
- A Role for Human DNA Polymerase λ in Alternative Lengthening of Telomeres (2021) (4)
- History and Discovery of DNA Polymerases (2010) (4)
- Effects of Drug Resistance Mutations L100I and V106A on the Binding of Pyrrolobenzoxazepinone Nonnucleoside Inhibitors to the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Catalytic Complex (2004) (4)
- Isolation of recombinant DNA elongation proteins. (2009) (4)
- Selective targeting of the HIV-1 reverse transcriptase catalytic complex through interaction with the "primer grip" region by pyrrolobenzoxazepinone non-nucleoside inhibitors correlates with increased activity towards drug-resistant mutants. (2008) (3)
- Two-dimensional DNA-fingerprinting in animals. (1991) (3)
- Photoreactive DNA probes as a tool for studying the translesion synthesis system in Mammalian cell extracts. (2008) (3)
- Neurons as a Model System for In Vivo Studies of the Possible Function of DNA Polymerases in DNA Replication and Repair Synthesis During Development (1978) (3)
- DNA polymerase delta and epsilon holoenzymes from calf thymus. (1992) (3)
- Modified gel electrophoresis for higher resolution of DNA fingerprints. (1988) (3)
- Cloning and expression of a cDNA encoding a catalytically active fragment of calf thymus DNA polymerase alpha. (1986) (3)
- Structural determinants of HIV-1 reverse transcriptase stereoselectivity towards (beta)-L-deoxy- and dideoxy-pyrimidine nucleoside triphosphates: molecular basis for the combination of L-dideoxynucleoside analogs with non-nucleoside inhibitors in anti HIV chemotherapy. (1999) (3)
- Human DNA polymerase : DNA elongation by the polymerase and terminal transferase activities are differentially coordinated by proliferating cell nuclear antigen and replication protein A (2004) (2)
- Effect of Beta-Lactam Antibiotics on Eukaryotic DNA Replication: Possible Impact on the Host-Parasite Relationship (1989) (2)
- DNA Polymerases: Eukaryotic (2005) (2)
- Production of active mouse DNA polymerase delta in bacteria. (1995) (2)
- Faculty Opinions recommendation of Genome instability due to ribonucleotide incorporation into DNA. (2010) (2)
- The Eukaryotic DNA Replication Fork (1997) (1)
- Human DNA Polymerases: Biology, Medicine and Biotechnology (2017) (1)
- The effect of drugs on mitochondrial DNA synthesis can be tested in isolated synaptosomes. (1986) (1)
- DNA methylation and DNA structure. (1984) (1)
- Structural and Functional Aspects of the Eukaryotic DNA Polymerase Families (2010) (1)
- Involvement of PARP1 in NF-kB-dependent gene expression during the cell cycle (2009) (1)
- Newly synthesized L-enantiomers of 3'-fluoro-modified beta-2'-deoxyribonucleoside 5'-triphosphates inhibit hepatitis B DNA polymerases but not the five cellular DNA polymerases alpha, beta, gamma, delta, and epsilon nor HIV-1 reverse transcriptase. (1998) (1)
- Detection and quantification of proviral DNA from feline immunodeficiency virus infected cats (1996) (1)
- Do DNA polymerases delta and alpha act coordinately as leading and lagging strand replicases? (1988) (1)
- DNA polymerase δ and ɛ holoenzymes from calf thymus (2006) (1)
- Mutant DNA polymerase delta from thermosensitive Schizosaccharomyces pombe strains display reduced stimulation by proliferating cell nuclear antigen. (1998) (1)
- Functions of DNA polymerases alpha, beta, and gamma in neurons during development. (1979) (1)
- Viral DNA Polymerases (2010) (0)
- Mammalian DNA polymerase alpha holoenzyme. (1984) (0)
- Structural homology amongcalf thymus a-polymerase polpeptides+ (1981) (0)
- DNA Polymerases and Chemotherapy (2010) (0)
- Interface between science and art: can art predict functions of enzymes? (2010) (0)
- Corrigendum: Generation of a Mono‐ubiquitinated PCNA Mimic by Click Chemistry (2011) (0)
- Properties and roles of DNA polymerases of Pyrococcus abyssi (2007) (0)
- Arthur Kornberg (1918–2007) (2008) (0)
- Structure of family X DNA polymerase from Deinococcus radiodurans (2009) (0)
- DNA Polymerases and Human Diseases (2018) (0)
- Faculty Opinions recommendation of Strandwise translocation of a DNA glycosylase on undamaged DNA. (2012) (0)
- Mammalian DNA polymerase alpha: a replication competent holoenzyme form from calf thymus. (1987) (0)
- Human DNA Polymerases: From Structure to Function (2018) (0)
- Specialized human DNA polymerases can incorporate ribonucleotides during lesion bypass and DNA repair (736.5) (2014) (0)
- Faculty Opinions recommendation of An in-frame deletion at the polymerase active site of POLD1 causes a multisystem disorder with lipodystrophy. (2013) (0)
- Faculty Opinions recommendation of Replication infidelity via a mismatch with Watson-Crick geometry. (2011) (0)
- Faculty Opinions recommendation of The hMsh2-hMsh6 complex acts in concert with monoubiquitinated PCNA and Pol η in response to oxidative DNA damage in human cells. (2011) (0)
- Review Eukaryotic DNA Replication (1990) (0)
- Mule Glycosylase by the E 3 Ubiquitin Ligase Regulation of Human MutYH DNA DNA and Chromosomes (2014) (0)
- Tandem purification of Mre11/Rad50-dimers using the Baculovirus (2019) (0)
- Year : 2002 Colocalization of human Rad 17 and PCNA in late S phase of the cell cycle upon replication (2006) (0)
- [DNA replication: mechanism and significance for general practice]. (1998) (0)
- DNA polymerase epsilon: in search of a function. (1992) (0)
- Market for Evolved DNA Polymerases in Routine and Medical Applications (2018) (0)
- Polymerase Chain Reaction and Heat-Stable DNA Polymerases: The History and the Potential of Evolved DNA Polymerases (2018) (0)
- Faculty Opinions recommendation of Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics. (2012) (0)
- Faculty Opinions recommendation of Human flap endonuclease structures, DNA double-base flipping, and a unified understanding of the FEN1 superfamily. (2011) (0)
- DETECTION OF PROTEIN-PROTEIN INTERACTIONS BY VARIATIONS OF THE YEAST TWO-HYBRID SYSTEM (2000) (0)
- Human DNA Polymerases and Chemotherapy (2018) (0)
- Global Functions of DNA Polymerases (2010) (0)
- History of DNA Polymerases (2018) (0)
- Human DNA Polymerases in Different DNA Transactions (2018) (0)
- Synthetic Evolution of DNA Polymerases with Novel Properties (2010) (0)
- Mammalian DNA Helicases, DNA Polymerases and DNA Polymerase Auxiliary Proteins (1993) (0)
- DNA Polymerases: General Aspects (2018) (0)
- Agnoprotein of polyomavirus BK interacts with proliferating cell nuclear antigen and inhibits DNA replication (2015) (0)
- Year : 2001 Okazaki fragment processing : modulation of the strand displacement activity of DNA polymerase delta by the concerted action of replication protein A , proliferating cell nuclear antigen , and flap endonuclease (2006) (0)
- A conserved domainofthelarge subunit of replication factor CbindsPCNAandactslike a dominant negative inhibitor ofDNA replication in (1996) (0)
- Stimulation of human DNA polymerase ! activity by Tim/Tipin (2013) (0)
- 157 Repair DNA polymerases as anticancer drug targets (2009) (0)
- Structural and Functional Aspects of the Prokaryotic and Archaea DNA Polymerase Families (2010) (0)
This paper list is powered by the following services:
What Schools Are Affiliated With Ulrich Hübscher?
Ulrich Hübscher is affiliated with the following schools:
