Ulrich Walter

Q: What Schools Are Affiliated With Ulrich Walter

Ulrich Walter is affiliated with the following schools: Yale University, University of Mainz, University of Cologne, University of Regensburg, Hannover Medical School, University of Hamburg, University of Basel, University of Birmingham, University of Washington, University of Würzburg

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Ulrich Walter

Physics

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#7127

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Physics

Ulrich Walter's Degrees

PhD Physics University of Cologne

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Ulrich Walter's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

NO at work (1994) (1500)
The nitric oxide and cGMP signal transduction system: regulation and mechanism of action. (1993) (805)
Effects of Angiotensin II Infusion on the Expression and Function of NAD(P)H Oxidase and Components of Nitric Oxide/cGMP Signaling (2002) (690)
The first comprehensive and quantitative analysis of human platelet protein composition allows the comparative analysis of structural and functional pathways. (2012) (629)
The proline‐rich focal adhesion and microfilament protein VASP is a ligand for profilins. (1995) (491)
Ca2+ current is regulated by cyclic GMP-dependent protein kinase in mammalian cardiac myocytes. (1991) (487)
Resistance to thienopyridines: Clinical detection of coronary stent thrombosis by monitoring of vasodilator‐stimulated phosphoprotein phosphorylation (2003) (482)
cAMP- and cGMP-dependent protein kinase phosphorylation sites of the focal adhesion vasodilator-stimulated phosphoprotein (VASP) in vitro and in intact human platelets. (1994) (460)
A novel proline‐rich motif present in ActA of Listeria monocytogenes and cytoskeletal proteins is the ligand for the EVH1 domain, a protein module present in the Ena/VASP family (1997) (420)
Distinct and specific functions of cGMP-dependent protein kinases. (1997) (412)
The 46/50 kDa phosphoprotein VASP purified from human platelets is a novel protein associated with actin filaments and focal contacts. (1992) (375)
Analysis and Regulation of Vasodilator-stimulated Phosphoprotein Serine 239 Phosphorylation in Vitro and in Intact Cells Using a Phosphospecific Monoclonal Antibody* (1998) (338)
Taming platelets with cyclic nucleotides. (2001) (333)
Flow Cytometry Analysis of Intracellular VASP Phosphorylation for the Assessment of Activating and Inhibitory Signal Transduction Pathways in Human Platelets (1999) (306)
The EVH2 Domain of the Vasodilator-stimulated Phosphoprotein Mediates Tetramerization, F-actin Binding, and Actin Bundle Formation* (1999) (296)
Immunohistochemical localization of cyclic GMP-dependent protein kinase in mammalian brain. (1981) (284)
A focal adhesion factor directly linking intracellularly motile Listeria monocytogenes and Listeria ivanovii to the actin‐based cytoskeleton of mammalian cells. (1995) (276)
Phosphorylation of focal adhesion vasodilator-stimulated phosphoprotein at Ser157 in intact human platelets correlates with fibrinogen receptor inhibition. (1994) (264)
Physiology and Pathophysiology of Vascular Signaling Controlled by Cyclic Guanosine 3′,5′-Cyclic Monophosphate–Dependent Protein Kinase (2003) (259)
Stoichiometric and reversible phosphorylation of a 46-kDa protein in human platelets in response to cGMP- and cAMP-elevating vasodilators. (1990) (255)
Cyclic GMP-dependent protein kinases and the cardiovascular system: insights from genetically modified mice. (2003) (255)
Microinjection of catalytic subunit of cyclic AMP-dependent protein kinase enhances calcium action potentials of bag cell neurons in cell culture. (1980) (250)
Specific impairment of human platelet P2Y(AC) ADP receptor-mediated signaling by the antiplatelet drug clopidogrel. (1999) (247)
Dysfunctional nitric oxide signalling increases risk of myocardial infarction (2013) (234)
Anatomy of cerebellar Purkinje cells in the rat determined by a specific immunohistochemical marker (1984) (231)
Megakaryocyte hyperplasia and enhanced agonist-induced platelet activation in vasodilator-stimulated phosphoprotein knockout mice. (1999) (228)
Molecular cloning, structural analysis and functional expression of the proline‐rich focal adhesion and microfilament‐associated protein VASP. (1995) (214)
Presynaptic and Postsynaptic Roles of NO, cGK, and RhoA in Long-Lasting Potentiation and Aggregation of Synaptic Proteins (2005) (205)
Molecular cloning, cDNA structure, and regulation of the regulatory subunit of type II cAMP-dependent protein kinase from rat ovarian granulosa cells. (1986) (200)
Platelet NAD(P)H-oxidase-generated ROS production regulates alphaIIbbeta3-integrin activation independent of the NO/cGMP pathway. (2005) (197)
Heterogeneous distribution of the cAMP receptor protein RII in the nervous system: evidence for its intracellular accumulation on microtubules, microtubule-organizing centers, and in the area of the Golgi complex (1986) (194)
Identification, purification, and characterization of a zyxin-related protein that binds the focal adhesion and microfilament protein VASP (vasodilator-stimulated phosphoprotein). (1995) (189)
Role of cGMP and cGMP-dependent protein kinase in nitrovasodilator inhibition of agonist-evoked calcium elevation in human platelets. (1992) (177)
The Human Platelet Membrane Proteome Reveals Several New Potential Membrane Proteins*S (2005) (173)
YC-1 potentiates nitric oxide- and carbon monoxide-induced cyclic GMP effects in human platelets. (1998) (173)
Functional and Biochemical Analysis of Endothelial (Dys)function and NO/cGMP Signaling in Human Blood Vessels With and Without Nitroglycerin Pretreatment (2002) (171)
High-affinity binding of the regulatory subunit (RII) of cAMP-dependent protein kinase to microtubule-associated and other cellular proteins. (1984) (167)
VASP interaction with vinculin: a recurring theme of interactions with proline‐rich motifs (1996) (162)
Concentration and regulation of cyclic nucleotides, cyclic-nucleotide-dependent protein kinases and one of their major substrates in human platelets. Estimating the rate of cAMP-regulated and cGMP-regulated protein phosphorylation in intact cells. (1992) (162)
Phosphoproteome of resting human platelets. (2008) (160)
Calcium-dependent membrane association sensitizes soluble guanylyl cyclase to nitric oxide (2002) (157)
Functional analysis of cGMP-dependent protein kinases I and II as mediators of NO/cGMP effects (1998) (157)
Physiology and pathophysiology of vascular signaling controlled by guanosine 3',5'-cyclic monophosphate-dependent protein kinase. (2004) (156)
Purification of a vasodilator-regulated phosphoprotein from human platelets. (1989) (156)
Cloning, expression, and in situ localization of rat intestinal cGMP-dependent protein kinase II. (1994) (154)
Nebivolol Prevents Vascular NOS III Uncoupling in Experimental Hyperlipidemia and Inhibits NADPH Oxidase Activity in Inflammatory Cells (2003) (153)
Regulation of the cellular and subcellular concentrations and distribution of cyclic nucleotide-dependent protein kinases. (1984) (149)
The bacterial actin nucleator protein ActA of Listeria monocytogenes contains multiple binding sites for host microfilament proteins (1995) (148)
Enhanced in vivo platelet adhesion in vasodilator-stimulated phosphoprotein (VASP)-deficient mice. (2004) (143)
Platelet membrane proteomics: a novel repository for functional research. (2009) (143)
Effects of In Vivo Nitroglycerin Treatment on Activity and Expression of the Guanylyl Cyclase and cGMP-Dependent Protein Kinase and Their Downstream Target Vasodilator-Stimulated Phosphoprotein in Aorta (2001) (142)
Thrombin and Collagen Induce a Feedback Inhibitory Signaling Pathway in Platelets Involving Dissociation of the Catalytic Subunit of Protein Kinase A from an NFκB-IκB Complex* (2010) (142)
Characterization of Sp-5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole- 3',5'-monophosphorothioate (Sp-5,6-DCl-cBiMPS) as a potent and specific activator of cyclic-AMP-dependent protein kinase in cell extracts and intact cells. (1991) (142)
EVH1 domains: structure, function and interactions (2002) (141)
Regulation of Human Endothelial Cell Focal Adhesion Sites and Migration by cGMP-dependent Protein Kinase I* (2000) (139)
Endogenous expression of type II cGMP-dependent protein kinase mRNA and protein in rat intestine. Implications for cystic fibrosis transmembrane conductance regulator. (1995) (139)
Novel role of the membrane-bound chemokine fractalkine in platelet activation and adhesion. (2004) (139)
Molecular cloning and predicted full‐length amino acid sequence of the type Iβ isozyme of cGMP‐dependent protein kinase from human placenta (1989) (137)
Expression of cGMP-dependent protein kinase I and phosphorylation of its substrate, vasodilator-stimulated phosphoprotein, in human endothelial cells of different origin. (1995) (136)
Analysis of the functional role of cGMP-dependent protein kinase in intact human platelets using a specific activator 8-para-chlorophenylthio-cGMP. (1992) (135)
Identification, characterization, and quantitative measurement of cyclic AMP receptor proteins in cytosol of various tissues using a photoaffinity ligand. (1977) (133)
Elucidation of N-Glycosylation Sites on Human Platelet Proteins (2006) (133)
Normalization of nomenclature for peptide motifs as ligands of modular protein domains (2002) (130)
Cytoskeleton assembly at endothelial cell–cell contacts is regulated by αII-spectrin–VASP complexes (2008) (128)
Vasodilator-stimulated protein phosphorylation in platelets is mediated by cAMP- and cGMP-dependent protein kinases. (1987) (125)
KT5823 Inhibits cGMP-dependent Protein Kinase Activity in Vitro but Not in Intact Human Platelets and Rat Mesangial Cells* (2000) (125)
Differential effects of diabetes on the expression of the gp91phox homologues nox1 and nox4. (2005) (125)
Mutations in Drosophila enabled and rescue by human vasodilator-stimulated phosphoprotein (VASP) indicate important functional roles for Ena/VASP homology domain 1 (EVH1) and EVH2 domains. (1998) (121)
The VASP tetramerization domain is a right-handed coiled coil based on a 15-residue repeat. (2004) (119)
Dipyridamole Enhances NO/cGMP-Mediated Vasodilator-Stimulated Phosphoprotein Phosphorylation and Signaling in Human Platelets: In Vitro and In Vivo/Ex Vivo Studies (2003) (118)
Role for peroxynitrite in the inhibition of prostacyclin synthase in nitrate tolerance. (2003) (117)
NO‐synthase‐/NO‐independent regulation of human and murine platelet soluble guanylyl cyclase activity (2008) (115)
AMP-activated Protein Kinase Impairs Endothelial Actin Cytoskeleton Assembly by Phosphorylating Vasodilator-stimulated Phosphoprotein* (2007) (114)
Role of cyclic nucleotide-dependent protein kinases and their common substrate VASP in the regulation of human platelets. (1993) (112)
Overexpression of human endothelial nitric oxide synthase in rat vascular smooth muscle cells and in balloon-injured carotid artery. (1998) (111)
Potent inhibition of human platelets by cGMP analogs independent of cGMP-dependent protein kinase. (2004) (110)
PKCdelta regulates collagen-induced platelet aggregation through inhibition of VASP-mediated filopodia formation. (2006) (108)
Real-time Monitoring of the PDE2 Activity of Live Cells (2005) (108)
An α-Actinin Binding Site of Zyxin Is Essential for Subcellular Zyxin Localization and α-Actinin Recruitment* (1999) (101)
Getting a first clue about SPRED functions (2007) (101)
Gut microbiota regulate hepatic von Willebrand factor synthesis and arterial thrombus formation via Toll-like receptor-2. (2017) (99)
Adenosine 3':5'-monophosphate receptor proteins in mammalian brain. (1978) (96)
What can proteomics tell us about platelets? (2014) (95)
Analysis of SAGE data in human platelets: Features of the transcriptome in an anucleate cell (2006) (94)
cGMP and cGMP-dependent protein kinase in platelets and blood cells. (2009) (93)
Immunological distinction between guanosine 3':5'-monophosphate-dependent and adenosine 3':5'-monophosphate-dependent protein kinases. (1980) (93)
Regulation of calcium mobilization and entry in human platelets by endothelium-derived factors. (1994) (92)
Activation of cGMP-dependent Protein Kinase Iβ Inhibits Interleukin 2 Release and Proliferation of T Cell Receptor-stimulated Human Peripheral T Cells* (2001) (92)
Demonstration of cGMP-dependent protein kinase and cGMP-dependent phosphorylation in cell-free extracts of platelets. (1986) (92)
Ligand specificity and ticlopidine effects distinguish three human platelet ADP receptors. (1998) (90)
Time-resolved characterization of cAMP/PKA-dependent signaling reveals that platelet inhibition is a concerted process involving multiple signaling pathways. (2014) (90)
Single L-type Ca(2+) channel regulation by cGMP-dependent protein kinase type I in adult cardiomyocytes from PKG I transgenic mice. (2003) (90)
Temporal quantitative phosphoproteomics of ADP stimulation reveals novel central nodes in platelet activation and inhibition. (2017) (90)
The role of VASP in regulation of cAMP- and Rac 1-mediated endothelial barrier stabilization. (2008) (89)
Expression of type II cGMP-dependent protein kinase in rat kidney is regulated by dehydration and correlated with renin gene expression. (1996) (87)
Platelet-localized FXI promotes a vascular coagulation-inflammatory circuit in arterial hypertension (2017) (84)
Gut Microbial Colonization Orchestrates TLR2 Expression, Signaling and Epithelial Proliferation in the Small Intestinal Mucosa (2014) (80)
A single loading dose of clopidogrel causes dose-dependent improvement of endothelial dysfunction in patients with stable coronary artery disease: results of a double-blind, randomized study. (2008) (79)
Frozen tissue sections as an experimental system to reveal specific binding sites for the regulatory subunit of type II cAMP-dependent protein kinase in neurons. (1982) (79)
Adverse effects of nitroglycerin treatment on endothelial function, vascular nitrotyrosine levels and cGMP-dependent protein kinase activity in hyperlipidemic Watanabe rabbits. (2002) (78)
Endogenous or overexpressed cGMP-dependent protein kinases inhibit cAMP-dependent renin release from rat isolated perfused kidney, microdissected glomeruli, and isolated juxtaglomerular cells. (1998) (77)
Enhanced N-Glycosylation Site Analysis of Sialoglycopeptides by Strong Cation Exchange Prefractionation Applied to Platelet Plasma Membranes *S (2007) (77)
Effects of oral niacin on endothelial dysfunction in patients with coronary artery disease: results of the randomized, double-blind, placebo-controlled INEF study. (2009) (77)
Signal transduction by cGMP-dependent protein kinases and their emerging roles in the regulation of cell adhesion and gene expression. (1999) (76)
Signal transduction by cGMP in heart (1991) (75)
Tracking functions of cGMP-dependent protein kinases (cGK). (2005) (75)
Immunocytochemical characterization of neuron-ricprimary cultures of embryonic rat brain cells by established neuronal and glial markers and by monospecific antisera against cyclic nucleotide-dependent protein kinases and the synaptic vesicle protein synapsin I (1986) (75)
Phosphorylation of vasodilator-stimulated phosphoprotein: a consequence of nitric oxide- and cGMP-mediated signal transduction in brain capillary endothelial cells and astrocytes. (1999) (74)
Platelet Protein Interactions: Map, Signaling Components, and Phosphorylation Groundstate (2008) (72)
Physiology and pathophysiology of vascular signaling controlled by guanosine 3',5'-cyclic monophosphate-dependent protein kinase [corrected]. (2003) (72)
Defective nitrovasodilator-stimulated protein phosphorylation and calcium regulation in cGMP-dependent protein kinase-deficient human platelets of chronic myelocytic leukemia. (1993) (71)
Effects of the NO/soluble guanylate cyclase/cGMP system on the functions of human platelets. (2018) (67)
Inhibition of platelet activation in congestive heart failure by aldosterone receptor antagonism and ACE inhibition (2003) (66)
Identification of endogenous substrate proteins for cAMP-dependent protein kinase in bovine brain. (1980) (66)
Platelets promote coagulation factor XII-mediated proteolytic cascade systems in plasma (2006) (65)
Vasodilator-stimulated phosphoprotein regulates proliferation and growth inhibition by nitric oxide in vascular smooth muscle cells. (2004) (65)
Distribution of cyclic-GMP-dependent protein kinase in various rat tissues and cell lines determined by a sensitive and specific radioimmunoassay. (2005) (65)
Purification and characterization of hormone-regulated isoforms of the regulatory subunit of type II cAMP-dependent protein kinase from rat ovaries. (1985) (64)
The cGMP-dependent protein kinase-gene, protein, and function (2004) (62)
Increased effects of C‐type natriuretic peptide on contractility and calcium regulation in murine hearts overexpressing cyclic GMP‐dependent protein kinase I (2003) (61)
Bradykinin regulates the level of guanosine 3′,5′-cyclic monophosphate (cyclic GMP) in neural cell lines (1984) (60)
Endothelial cell-dependent phosphorylation of a platelet protein mediated by cAMP- and cGMP-elevating factors. (1991) (59)
Platelet regulation by NO/cGMP signaling and NAD(P)H oxidase-generated ROS. (2006) (59)
Vasodilator‐stimulated phosphoprotein is a substrate for protein kinase C (2004) (59)
Gene Disruption of Spred-2 Causes Dwarfism* (2005) (58)
Phosphorylation of Vasodilator-Stimulated Phosphoprotein Prevents Platelet-Neutrophil Complex Formation and Dampens Myocardial Ischemia-Reperfusion Injury (2011) (58)
Expression and subcellular localization of Spred proteins in mouse and human tissues (2004) (57)
Expression, purification, and characterization of the cGMP‐dependent protein kinases Iβ and II using the baculovirus system (1995) (57)
Dephosphorylation of the focal adhesion protein VASP in vitro and in intact human platelets (1995) (56)
Insulin stimulates the L-type Ca2+ current in rat cardiac myocytes. (1999) (56)
Identification of profilin and src homology 3 domains as binding partners for Drosophila enabled. (1999) (56)
Stimulation of L-type Ca2+ current in human atrial myocytes by insulin. (1999) (55)
Indirect regulation of Ca2+ entry by cAMP-dependent and cGMP-dependent protein kinases and phospholipase C in rat platelets. (1994) (53)
Presence of free cyclic AMP receptor protein and regulation of its level by cyclic AMP in neuroblastoma-glioma hybrid cells. (1979) (53)
The neural type II regulatory subunit of cAMP-dependent protein kinase is present and regulated by hormones in the rat ovary. (1986) (52)
HIV-1 gp120 receptor on CD4-negative brain cells activates a tyrosine kinase. (1992) (51)
Increased Spreading, Rac/p21-activated Kinase (PAK) Activity, and Compromised Cell Motility in Cells Deficient in Vasodilator-stimulated Phosphoprotein (VASP)* (2002) (51)
Endothelium-dependent and -independent relaxation and VASP serines 157/239 phosphorylation by cyclic nucleotide-elevating vasodilators in rat aorta. (2003) (50)
Distribution, cellular localization, and postnatal development of VASP and Mena expression in mouse tissues (2001) (50)
Quality of oral anticoagulation with phenprocoumon in regular medical care and its potential for improvement in a telemedicine-based coagulation service – results from the prospective, multi-center, observational cohort study thrombEVAL (2015) (50)
Phosphorylation of CalDAG‐GEFI by protein kinase A prevents Rap1b activation (2013) (50)
Inhibition of agonist-induced p42 and p38 mitogen-activated protein kinase phosphorylation and CD40 ligand/P-selectin expression by cyclic nucleotide-regulated pathways in human platelets. (2000) (47)
Differentiation of cGMP-dependent and -independent nitric oxide effects on platelet apoptosis and reactive oxygen species production using platelets lacking soluble guanylyl cyclase (2011) (47)
Dibutyryl cAMP treatment of neuroblastoma‐glioma hybrid cells results in selective increase in cAMP‐receptor protein (R‐I) as measured by monospecific antibodies. (1983) (47)
cDNA cloning of porcine p42IP4, a membrane‐associated and cytosolic 42 kDa inositol(1,3,4,5)tetrakisphosphate receptor from pig brain with similarly high affinity for phosphatidylinositol (3,4,5)P3 (1997) (47)
An alpha-actinin binding site of zyxin is essential for subcellular zyxin localization and alpha-actinin recruitment. (1999) (46)
Study of autophosphorylation of isoenzymes of cyclic AMP-dependent protein kinases. (1977) (46)
Steroid hormones may regulate autophosphorylation of adenosine-3',5'-monophosphate-dependent protein kinase in target tissues. (1981) (45)
Dual role of the p38 MAPK/cPLA2 pathway in the regulation of platelet apoptosis induced by ABT-737 and strong platelet agonists (2013) (45)
Thrombin stimulation of p38 MAP kinase in human platelets is mediated by ADP and thromboxane A2 and inhibited by cGMP/cGMP-dependent protein kinase. (2007) (45)
Disruption of cardiac Ena-VASP protein localization in intercalated disks causes dilated cardiomyopathy. (2003) (45)
Cyclic nucleotide elevating vasodilators inhibit platelet aggregation at an early step of the activation cascade. (1989) (43)
Vasodilator-stimulated Phosphoprotein Activation of Serum-response Element-dependent Transcription Occurs Downstream of RhoA and Is Inhibited by cGMP-dependent Protein Kinase Phosphorylation* (2004) (43)
cGMP-dependent protein kinase is present in high concentrations in contractile cells of the kidney vasculature. (1986) (42)
Cofactor‐independent human antiphospholipid antibodies induce venous thrombosis in mice (2016) (41)
The Microbiota Promotes Arterial Thrombosis in Low-Density Lipoprotein Receptor-Deficient Mice (2019) (40)
Platelet NAD(P)H-oxidase–generated ROS production regulates IIb 3-integrin activation independent of the NO/cGMP pathway (2005) (39)
Understanding platelets (2005) (39)
Regulation of aldosterone production from zona glomerulosa cells by ANG II and cAMP: evidence for PKA-independent activation of CaMK by cAMP. (2006) (39)
Inflammation‐associated repression of vasodilator‐stimulated phosphoprotein (VASP) reduces alveolar‐capillary barrier function during acute lung injury (2009) (38)
Downregulation of AKT reverses platinum resistance of human ovarian cancers in vitro. (2012) (37)
Catalytic subunit of cAMP‐dependent protein kinase is essential for cAMP‐mediated mammalian gene expression (1988) (37)
Evidence for anti-angiogenic and pro-survival functions of the cerebral cavernous malformation protein 3 (2010) (36)
Synergistic phosphorylation of the focal adhesion-associated vasodilator-stimulated phosphoprotein in intact human platelets in response to cGMP- and cAMP-elevating platelet inhibitors. (1994) (35)
The vasodilator-stimulated phosphoprotein (VASP): target of YC-1 and nitric oxide effects in human and rat platelets. (2000) (35)
Cyclic AMP-dependent and cyclic GMP-dependent protein kinases of nervous tissue. (1981) (35)
Relaxation, equilibrium oligomerization, and molecular symmetry of the VASP (336-380) EVH2 tetramer. (2002) (34)
Adenosine 3',5'-monophosphate-dependent protein kinase and granulosa cell responsiveness to gonadotropins. (1984) (34)
Vasodilator-Stimulated Phosphoprotein Regulates Proliferation and Growth Inhibition by Nitric Oxide in Vascular Smooth Muscle Cells (2004) (34)
ADP-induced platelet aggregation frequently fails to detect impaired clopidogrel-responsiveness in patients with coronary artery disease compared to a P2Y12-specific assay (2008) (33)
The VASP-Spred-Sprouty Domain Puzzle* (2006) (32)
Intracellular mechanism of action of vasodilators. (1988) (32)
Identification of the cyclic AMP-dependent protein kinase responsible for endogenous phosphorylation of substrate proteins in synaptic membrane fraction from rat brain. (1979) (31)
Roles of cGMP/cGMP-dependent protein kinase in platelet activation. (2004) (31)
Human cyclic GMP-dependent protein kinase I beta overexpression increases phosphorylation of an endogenous focal contact-associated vasodilator-stimulated phosphoprotein without altering the thrombin-evoked calcium response. (1994) (31)
Vasodilator-stimulated phosphoprotein-deficient mice demonstrate increased platelet activation but improved renal endothelial preservation and regeneration in passive nephrotoxic nephritis. (2005) (31)
Molecular cloning and predicted full-length amino acid sequence of the type I beta isozyme of cGMP-dependent protein kinase from human placenta. Tissue distribution and developmental changes in rat. (1989) (30)
Distribution and Activation of cAMP- and cGMP-Dependent Protein Kinases in Highly Purified Human Platelet Plasma and Intracellular Membranes (1996) (29)
Low angle light scattering analysis: a novel quantitative method for functional characterization of human and murine platelet receptors (2011) (29)
Vasodilator-Stimulated Phosphoprotein (VASP)-dependent and -independent pathways regulate thrombin-induced activation of Rap1b in platelets (2016) (28)
Design of N-substituted Peptomer Ligands for EVH1 Domains* (2003) (27)
The sGC stimulator riociguat inhibits platelet function in washed platelets but not in whole blood (2015) (26)
Reciprocal regulation of human platelet function by endogenous prostanoids and through multiple prostanoid receptors. (2014) (25)
A cGMP-Dependent Protein Kinase Assay for High Throughput Screening Based on Time-Resolved Fluorescence Resonance Energy Transfer (2001) (24)
Analysis, purification and properties of a 50,000-dalton membrane-associated phosphoprotein from human platelets. (1990) (24)
Photoaffinity labeling of the regulatory subunit of cAMP-dependent protein kinase. (1983) (24)
Lack of T-bet reduces monocytic interleukin-12 formation and accelerates thrombus resolution in deep vein thrombosis (2018) (23)
Use of functional highly purified human platelets for the identification of new proteins of the IPP signaling pathway. (2008) (23)
Alterations of the platelet proteome in type I Glanzmann thrombasthenia caused by different homozygous delG frameshift mutations in ITGA2B (2017) (22)
Erythrocytes do not activate purified and platelet soluble guanylate cyclases even in conditions favourable for NO synthesis (2016) (22)
Protein kinases in developing rat brain. (1978) (22)
Response: platelet transcriptome and proteome--relation rather than correlation. (2013) (22)
Rationale and design of three observational, prospective cohort studies including biobanking to evaluate and improve diagnostics, management strategies and risk stratification in venous thromboembolism: the VTEval Project (2015) (22)
High expression of the focal adhesion- and microfilament-associated protein VASP in vascular smooth muscle and endothelial cells of the intact human vessel wall (1996) (21)
Cyclic nucleotide-regulated proliferation and differentiation vary in human hematopoietic progenitor cells derived from healthy persons, tumor patients, and chronic myelocytic leukemia patients. (2008) (21)
Vasodilator-Stimulated Phosphoprotein Regulates Inside-Out Signaling of β2 Integrins in Neutrophils (2010) (21)
Phosphatidylserine surface expression and integrin αIIbβ3 activity on thrombin/convulxin stimulated platelets/particles of different sizes (2009) (21)
Comparison of vasodilatory prostaglandins with respect to cAMP-mediated phosphorylation of a target substrate in intact human platelets. (1991) (20)
Quantitative analysis of the cardiac fibroblast transcriptome-implications for NO/cGMP signaling. (2004) (20)
Endothelium-dependent phosphorylation of vasodilator-stimulated protein in platelets during coronary passage. (1994) (20)
Protein kinase A activation by the anti-cancer drugs ABT-737 and thymoquinone is caspase-3-dependent and correlates with platelet inhibition and apoptosis (2017) (20)
Insulin inhibition of platelet‐endothelial interaction is mediated by insulin effects on endothelial cells without direct effects on platelets (2008) (20)
Photoaffinity labeling of a guanosine 3':5'-monophosphate-dependent protein kinase from vascular smooth muscle. (1978) (20)
Deciphering of ADP‐induced, phosphotyrosine‐dependent signaling networks in human platelets by Src‐homology 2 region (SH2)‐profiling (2013) (19)
Increased noise sensitivity and altered inner ear MENA distribution in VASP−/− mice (2004) (18)
The oligopeptide DT‐2 is a specific PKG I inhibitor only in vitro, not in living cells (2012) (18)
Tissue-specific Spred-2 promoter activity characterized by a gene trap approach. (2006) (18)
The Cell Cycle Checkpoint System MAST(L)-ENSA/ARPP19-PP2A is Targeted by cAMP/PKA and cGMP/PKG in Anucleate Human Platelets (2020) (18)
Platelet-vessel wall interactions, focal adhesions, and the mechanism of action of endothelial factors. (1995) (17)
VASP phosphorylation at serine239 regulates the effects of NO on smooth muscle cell invasion and contraction of collagen (2010) (17)
Regulation of gene expression by transfected subunits of cAMP-dependent protein kinase. (1990) (16)
Hypoxia impairs agonist-induced integrin αIIbβ3 activation and platelet aggregation (2017) (16)
Differential roles of cAMP and cGMP in megakaryocyte maturation and platelet biogenesis. (2013) (16)
Localization of the human gene for the type I cyclic GMP-dependent protein kinase to chromosome 10. (1992) (16)
Immune escape of AKT overexpressing ovarian cancer cells. (2013) (15)
Fine mapping of the H-kininogen binding site in plasma prekallikrein apple domain 2. (2002) (15)
Dynamic Interaction between Src and C-terminal Src Kinase in Integrin αIIbβ3-mediated Signaling to the Cytoskeleton* (2007) (15)
Inhibition of platelet P2Y12 and alpha2A receptor signaling by cGMP-dependent protein kinase. (2002) (15)
Identification of SPRED2 (Sprouty-related Protein with EVH1 Domain 2) as a Negative Regulator of the Hypothalamic-Pituitary-Adrenal Axis* (2011) (15)
Cloning of the VASP (vasodilator-stimulated phosphoprotein) genes in human and mouse: structure, sequence, and chromosomal localization. (1996) (14)
Does the NO/sGC/cGMP/PKG pathway play a stimulatory role in platelets? (2012) (14)
Studies on regulation and cellular localization of cAMP- and cGMP-dependent protein kinases. (1982) (13)
Deficiency of Vasodilator-Stimulated Phosphoprotein (VASP) Increases Blood-Brain-Barrier Damage and Edema Formation after Ischemic Stroke in Mice (2010) (13)
Soluble guanylyl cyclase is the only enzyme responsible for cyclic guanosine monophosphate synthesis in human platelets (2013) (12)
Dephosphorylation of cAMP-dependent protein kinase regulatory subunit in stimulated parietal cells. (1992) (12)
cAMP- and cGMP-elevating agents inhibit GPIbα-mediated aggregation but not GPIbα-stimulated Syk activation in human platelets (2019) (12)
The thrombin inhibitors hirudin and Refludan® activate the soluble guanylyl cyclase and the cGMP pathway in washed human platelets (2012) (12)
CD36‐fibrin interaction propagates FXI‐dependent thrombin generation of human platelets (2020) (12)
Quantitative labeling of the regulatory subunit of type II cAMP-dependent protein kinase from bovine heart by a photoaffinity analog. (1978) (12)
Protein phosphorylation regulated by cyclic nucleotide-dependent protein kinases in cell extracts and in intact human lymphocytes. (1992) (11)
Hypoxia evokes increased PDI and PDIA6 expression in the infarcted myocardium of ex-germ-free and conventionally raised mice (2018) (11)
Characterization of a Novel Interaction Between Vasodilator-Stimulated Phosphoprotein and Abelson Interactor 1 in Human Platelets: A Concerted Computational and Experimental Approach (2010) (11)
Expression of VASP and zyxin in cochlear pillar cells: indication for actin-based dynamics? (2003) (11)
The Thr715Pro variant impairs terminal glycosylation of P-selectin (2012) (10)
Red blood cell sodium and potassium after hydrochlorothiazide (1981) (10)
Prostaglandin-induced VASP phosphorylation controls alpha II-spectrin breakdown in apoptotic cells. (2008) (10)
Type II cAMP-dependent protein kinase regulatory subunit-binding proteins. (1988) (10)
Feedback Regulation of Syk by Protein Kinase C in Human Platelets (2019) (10)
Inhibition of rat cardiac fibroblast growth by cAMP – but not by cGMP-dependent protein kinase (2001) (10)
Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications (2017) (10)
Dynamic interaction between Src and C-terminal Src kinase in integrin alphaIIbbeta3-mediated signaling to the cytoskeleton. (2007) (10)
New Insights into Platelet Signalling Pathways by Functional and Proteomic Approaches (2018) (9)
Anti-Inflammatory and Anti-Thrombotic Effects of the Fungal Metabolite Galiellalactone in Apolipoprotein E-Deficient Mice (2015) (9)
Inhibition of platelet function by cyclic nucleotides and cyclic nucleotide-dependent protein kinases (1991) (9)
Echicetin Coated Polystyrene Beads: A Novel Tool to Investigate GPIb-Specific Platelet Activation and Aggregation (2014) (9)
Effect of ouabain and furosemide on erythrocyte sodium and phosphate transport (1981) (9)
The RhoA regulators Myo9b and GEF‐H1 are targets of cyclic nucleotide‐dependent kinases in platelets (2020) (8)
Signal transduction and cyclic nucleotides in human platelets (1994) (8)
Determination of cyclic AMP-dependent protein kinase subunits by an immunoassay reveals a different subcellular distribution of the enzyme in rat parotid than does determination of the enzyme activity. (1985) (8)
Interaction of the Regulatory Subunit (RII) of cAMP‐Dependent Protein Kinase with Tissue‐Specific Binding Proteins Including Microtubule‐Associated Proteins a (1986) (7)
Effects of Angiotensin II Infusion on the Expression and Function of NAD(P)H Oxidase (2002) (7)
Letter to the Editor: 1H, 13C and 15N Resonance Assignment of the Human Spred2 EVH1 Domain (2004) (6)
Hearing development and spiral ganglion neurite growth in VASP deficient mice (2007) (6)
Selective increase of R-I subunit of cyclic AMP-dependent protein kinase in glia-rich primary cultures upon treatment with dibutyryl cyclic AMP (1985) (6)
Properties and regulation of human platelet cation channels. (1993) (6)
Vasodilator‐stimulated phosphoprotein deficiency potentiates PAR‐1‐induced increase in endothelial permeability in mouse lungs (2011) (6)
Photoaffinity Labeling of Cyclic AMP-Dependent and Cyclic GMP-Dependent Protein Kinases (1982) (6)
Thrombin stimulation of p 38 MAP kinase in human platelets is mediated by ADP and thromboxane A 2 and inhibited by cGMP / cGMP-dependent protein kinase (2006) (5)
cAMP-Dependent Protein Kinase: Subunit Diversity and Functional Role in Gene Expression (1990) (5)
Signal Transduction by Cyclic Nucleotide-Dependent Protein Kinases in Platelets (1997) (5)
Fine-Tuning of Platelet Responses by Serine/Threonine Protein Kinases and Phosphatases—Just the Beginning (2021) (4)
cGMP and PKG Signaling in Platelets (2010) (4)
Prostaglandin-E 1 - and Sodium Nitroprusside-Regulated Protein Phosphorylation in Platelets (1987) (4)
The Serine/Threonine Protein Phosphatase 2A (PP2A) Regulates Syk Activity in Human Platelets (2020) (4)
Insulin fails to modulate the cardiac L-Type Ca2+ current in Type II diabetes patients – a possible link to cardiac dysfunction in diabetes mellitus (2001) (3)
Purification and assays of vasodilator-stimulated phosphoprotein. (1998) (3)
Delayed Formation of Actin Filaments in the Outer Pillar Head Plate of VASP–/– Mice (2007) (3)
Cyclin Y Is Expressed in Platelets and Modulates Integrin Outside-in Signaling (2020) (2)
Clopidogrel Salts - Pharmacokinetic, Pharmakodynamic and Clinical Aspects (2009) (2)
Differential regulation of platelet inhibition by cGMP- and cAMP-dependent protein kinases (2013) (2)
Reduced vascular nitric oxide bioavailability in diabetes increases platelet activation in vivo: Rescue by endothelium-specific restoration of vascular NO production (2003) (1)
PKCδ Regulates Platelet Activity through the Inhibition of VASP-Mediated Filopodia Formation. (2006) (1)
Differential regulation of platelet inhibition by cGMP- and cAMP-dependent protein kinases (2013) (1)
C ytoskeleton assembly at endothelial cell – cell contacts is regulated by (cid:2) II-spectrin – VASP complexes (2008) (1)
NO inhibits platelet apoptosis by cGMP-dependent and-independent pathways (2009) (1)
cAMP- and cGMP-elevating agents inhibit GPIbα-mediated aggregation but not GPIbα-stimulated Syk activation in human platelets (2019) (1)
Molecular Cloning, cDNA Structure, and Regulation of the Regulatory Subunit of Type I1 CAMP-dependent Protein Kinase from Rat Ovarian Granulosa Cells* (2001) (1)
Inhibition of molybdenum blue formation by ATP (1981) (1)
Platelet inhibitory effects of the NO independent sGC stimulator riociguat (Bay 63-2561) (2013) (1)
Molecular Cloning of a Hormone‐regulated Isoform of the Regulatory Subunit of Type II cAMP‐dependent Protein Kinase from Rat Ovaries (1986) (1)
Novel role for the membrane-bound chemokine fractalkine: A pathophysiologically relevant mechanism in platelet activation and adhesion (2003) (1)
Immunoelectron microscopical and immunohistochemical localisation of VASP in vascular smooth muscle cells of normal and arteriosclerotic vessels (1993) (1)
Erratum: Mutations in Drosophila enabled and rescue by human vasodilator-stimulated phosphoprotein (VASP) indicate important functional roles for Ena/VASP homology domain 1 (EVH1) and EVH2 domains (Molecular Biology of the Cell (1998) 9 (2157-2171)) (1999) (1)
activation and adhesion Novel role of the membrane-bound chemokine fractalkine in platelet (2010) (1)
Erythrocytes do not produce biologically active NO (2015) (1)
Vasodilator-Stimulated Phosphoprotein (VASP)-dependent and -independent pathways regulate thrombin-induced activation of Rap1b in platelets (2016) (1)
Interaction of Vasodilator‐stimulated phosphoprotein (VASP) with αII‐Spectrin is crucial for the cAMP‐dependent regulation of cortical actin dynamics (2006) (1)
Vessels With and Without Nitroglycerin Pretreatment Functional and Biochemical Analysis of Endothelial ( Dys ) function and NO / cGMP (2002) (0)
Immunohistochemical localization 4 protein kinase in mammalian brain (Purkinje cell/protein phosphorylation/blood vessels/smooth muscle 4 (2016) (0)
Functional role of cGMP-dependent VASP phosphorylation in vascular cells (2005) (0)
Hypoxia impairs agonist-induced integrin αIIbβ3 activation and platelet aggregation (2017) (0)
Specific PKG inhibitors: do they really exist? (2011) (0)
human VASP tetramerisation domain (2004) (0)
Towards an extensive proteome analysis of platelet membranes (2005) (0)
Multiple Cyclic GMP Binding Proteins Involved in the Regulation of Cardiac Calcium Channels (1993) (0)
Table of Contents (1995) (0)
Correlation between Mononuclear Infiltration and Changes in VASP Phosphorylation Patterns after Heterotopic Cardiac Transplantation in the Rat (2003) (0)
Us About Platelets ? Assessment of Platelet Function and the Arguable Need for More Antiplatelet Drugs Genomics of Megakaryocytes and Platelets (2014) (0)
Platelet-Localized FXI Promotes a Glycoprotein Ib Alpha Dependent Feedback Loop in Arterial Hypertension and Vascular Inflammation (2015) (0)
SOLUTION STRUCTURE OF THE ENA-VASP HOMOLOGY 1 (EVH1) DOMAIN OF HUMAN VASODILATOR-STIMULATED PHOSPHOPROTEIN (VASP) (2000) (0)
Solution structure and resonance assignment of the N-terminal EVH1 domain from the human Spred2 protein (Sprouty-related protein with EVH1 domain isoform 2) (2007) (0)
2.32 Novel aspects of the von Willebrand factor – platelet glycoprotein IB interaction and signaling (2012) (0)
Drug interactions with cyclic nucleotide and protein phosphorylation systems. (1979) (0)
In vivo modulation of vasodilator stimulated phosphoprotein functions by phosphorylation (2005) (0)
Spred‐2‐deficiency results in dwarfism and kidney failure (2006) (0)
Quantitative and functional analysis of the NO/sGC/cGMP/VASP pathway in-vitro and in-vivo (2003) (0)
cGMP regulates hematopoietic stem cell proliferation and differentiation (2003) (0)
The Hemofiltrate of Human Patients: A Favourable Source of Endogenous Digitalis-Like Substances (1993) (0)
Abstract 1176: A Single Dose of Clopidogrel Causes Dose-Dependent Improvement of Endothelial Dysfunction in Patients with Stable Coronary Artery Disease (2006) (0)
Abstract 1003: Nitric Oxide-Dependent Phosphorylation of Vasodilator-Stimulated Phosphoprotein Regulates Vascular Smooth Muscle Cell Contraction, Adhesion and Spreading (2006) (0)
Platelet Alpha-Storage Pool Defect Combined with Non-Classic Delta-Storage Pool Deficiency - with a Severe Bleeding Tendency (2016) (0)
Abstract 32: Coagulation Factor XI and Thrombin Mediate Angiotensin II-induced Vascular Dysfunction (2015) (0)
Dynamic Regulation of Src by Csk in Integrin α IIb β 3 Mediated Signalling. (2005) (0)
cGMP dependent protein kinase type II regulates basal level of aldosterone release from zona glomerulosa cells without activating StAR gene expression (2003) (0)
Characterization of the interaction of alkaline phosphatase with an activity inhibiting monoclonal antibody by progress curve analysis. (1995) (0)
STRUCTURE OF THE ENA-VASP HOMOLOGY 1 (EVH1) DOMAIN OF HUMAN VASODILATOR-STIMULATED PHOSPHOPROTEIN (VASP) in Complex with SFEFPPPPTEDEL peptide (Theoretical Model) (2001) (0)
Potential and limitations of PKA/ PKG inhibitors for platelet studies (2021) (0)
Regulation of Nitric Oxide–Sensitive Guanylyl Cyclase Cyclic GMP Phosphodiesterases and Regulation of Smooth Muscle Function Structure, Regulation, and Function of Mammalian Membrane Guanylyl Cyclase Receptors, With a Focus on Guanylyl Cyclase-A Cyclic GMP–Dependent Protein Kinases and the Cardiovas (2003) (0)
Clopidogrel Salts Clopidogrel Salts – Pharmacokinetic , Pharmacodynamic and Clinical Aspects (2018) (0)
NO/cGMP/PKG pathway in platelets: inhibitory but not stimulatory (2007) (0)
Reparation of glomerular damage in anti-GBM nephritis is improved in VASP-knockout mice (2002) (0)
Assembly of an in silico model of the platelet interactome and in vitro validation of IPP complex interactions of human platelets (2007) (0)
United States Patent 19 Genieser et al . 54 ) . DERIVATIVES OF CYCLIC GUANOSINE-3 ' (2017) (0)
Dependent Protein Kinase −-Cyclic Monophosphate ′ , 5 ′ Physiology and Pathophysiology of Vascular Signaling Controlled by Cyclic Guanosine 3 (2003) (0)
Table of Contents (1995) (0)
Defective Nitric Oxide / cGMP Signaling and Endothelial Dysfunction Vasodilator-Stimulated Phosphoprotein Serine 239 Phosphorylation as a Sensitive (2000) (0)
Abstract 18216: Essential Role of Platelet Glycoprotein Ibα Dependent Thrombin-FXI Feedback Loop in Arterial Hypertension, Vascular Dysfunction and Inflammation (2015) (0)
Subunit of Protein Kinase A from an NF Involving Dissociation of the Catalytic Inhibitory Signaling Pathway in Platelets Thrombin and Collagen Induce a Feedback Signal Transduction : (2010) (0)
Cross-talk of inhibitory and stimulatory signalling pathways of human platelets (2009) (0)
Normalization of Nomenclature for Functional Peptide Motifs as Ligands of Modular Protein Domains (2002) (0)
Platelet inhibitory effects of the NO independent sGC stimulator riociguat (Bay 63-2561) (2013) (0)
Differential Regulation of GPVI-Induced Btk and Syk Activation by PKC, PKA and PP2A in Human Platelets (2023) (0)
Inhibition of agonist-stimulated aldosterone production from adrenal zona glomerulosa cells by ANP is mediated by GC-A (2005) (0)
Erythrocytes do not activate purified and platelet soluble guanylate cyclases even in conditions favourable for NO synthesis (2016) (0)
Increased tissue expression and activity of cGMP-dependent protein kinase I in ANP-receptor (GC-A) – deficient mice (2005) (0)
correlation relation rather than − − Response : platelet transcriptome and proteome (2013) (0)
Identification, purification, and characterization of a zyxin- related protein that binds the focal adhesion and microfilament protein VASP (2005) (0)
: advise in design and interpretation of platelet ROS experiments (2005) (0)
human VASP tetramerisation domain L352M (2004) (0)
Web sequence gazing (1998) (0)
Editorial: Analysis of Platelet Function and Dysfunction – From Pathobiochemistry to Diagnostics – (2002) (0)

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