Ulrike Holzgrabe

Q: What Schools Are Affiliated With Ulrike Holzgrabe

Ulrike Holzgrabe is affiliated with the following schools: Kiel University, University of Jena, University of Würzburg, University of Bonn

Ulrike Holzgrabe's AcademicInfluence.com Rankings

Ulrike Holzgrabe

Chemistry

#3562

World Rank

#4588

Historical Rank

Organic Chemistry

#562

World Rank

#649

Historical Rank

chemistry Degrees

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Chemistry

Ulrike Holzgrabe's Degrees

PhD Chemistry University of Bonn
Masters Chemistry University of Bonn

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Ulrike Holzgrabe's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Quantitative NMR spectroscopy in pharmaceutical applications. (2010) (255)
Quaternary Ammonium Salts and Their Antimicrobial Potential: Targets or Nonspecific Interactions? (2012) (238)
Quantitative NMR spectroscopy--applications in drug analysis. (2005) (200)
Targeting acetylcholinesterase to treat neurodegeneration (2007) (174)
Comparison of Pharmacological Activities of Three Distinct κ Ligands (Salvinorin A, TRK-820 and 3FLB) on κ Opioid Receptors in Vitro and Their Antipruritic and Antinociceptive Activities in Vivo (2005) (172)
Penetration of Antibacterials into Bone (2009) (157)
Dualsteric GPCR targeting: a novel route to binding and signaling pathway selectivity (2009) (141)
Penetration of antibacterials into bone: pharmacokinetic, pharmacodynamic and bioanalytical considerations. (2009) (138)
NMR techniques in biomedical and pharmaceutical analysis. (2011) (129)
NMR spectroscopy in pharmacy. (1998) (121)
NMR spectroscopy in pharmaceutical analysis (2008) (119)
The allosteric vestibule of a seven transmembrane helical receptor controls G-protein coupling (2012) (114)
Rational design of dualsteric GPCR ligands: quests and promise (2010) (108)
Systematic Comparison of the Population Pharmacokinetics and Pharmacodynamics of Piperacillin in Cystic Fibrosis Patients and Healthy Volunteers (2007) (108)
Analytical challenges in drug counterfeiting and falsification-The NMR approach. (2011) (99)
Evaluation by Monte Carlo Simulation of the Pharmacokinetics of Two Doses of Meropenem Administered Intermittently or as a Continuous Infusion in Healthy Volunteers (2005) (96)
Vibrational spectroscopic characterization of fluoroquinolones. (2005) (95)
Allosteric ligands for G protein‐coupled receptors: A novel strategy with attractive therapeutic opportunities (2010) (94)
Charged aerosol detection in pharmaceutical analysis. (2012) (91)
'Pro et contra' ionic liquid drugs - Challenges and opportunities for pharmaceutical translation. (2015) (84)
Quality assessment of unfractionated heparin using 1H nuclear magnetic resonance spectroscopy. (2008) (84)
Photocatalyzed [2 + 2 + 2]-cycloaddition of nitriles with acetylene: an effective method for the synthesis of 2-pyridines under mild conditions. (2002) (84)
Molecular alliance-from orthosteric and allosteric ligands to dualsteric/bitopic agonists at G protein coupled receptors. (2013) (81)
Acetylcholinesterase inhibitors with photoswitchable inhibition of β-amyloid aggregation. (2014) (81)
Aziridine-2,3-dicarboxylate inhibitors targeting the major cysteine protease of Trypanosoma brucei as lead trypanocidal agents. (2006) (76)
Characterization of bacterial growth and the influence of antibiotics by means of UV resonance Raman spectroscopy. (2006) (71)
Design, synthesis, and action of oxotremorine-related hybrid-type allosteric modulators of muscarinic acetylcholine receptors. (2006) (70)
[Opioid agonists and antagonists, opioid receptors]. (1997) (68)
Analysis of the glucosinolate pattern of Arabidopsis thaliana seeds by capillary zone electrophoresis coupled to electrospray ionization‐mass spectrometry (2005) (64)
Why not using capillary electrophoresis in drug analysis? (2006) (64)
Inhibition of cytochrome P450 3A4 by extracts and kavalactones of Piper methysticum (Kava-Kava). (2002) (62)
Plasma protein binding of gyrase inhibitors. (1998) (61)
Ligand Binding Ensembles Determine Graded Agonist Efficacies at a G Protein-coupled Receptor* (2016) (60)
Allosteric modulators of ligand binding to muscarinic acetylcholine receptors (1998) (60)
Determination of binding constants of cyclodextrin inclusion complexes with amino acids and dipeptides by potentiometric titration. (2004) (60)
Valeriana wallichii root extracts and fractions with activity against Leishmania spp (2011) (58)
Agonists with supraphysiological efficacy at the muscarinic M2 ACh receptor (2013) (58)
Transformation of acidic poorly water soluble drugs into ionic liquids. (2015) (58)
Population Pharmacokinetics at Two Dose Levels and Pharmacodynamic Profiling of Flucloxacillin (2007) (58)
Structure−Activity Relationships in a Series of Bisquaternary Bisphthalimidine Derivatives Modulating the Muscarinic M2-Receptor Allosterically (2000) (57)
NMR spectroscopy in drug development and analysis (1999) (57)
Chiral separations by cyclodextrin-modified capillary electrophoresis – Determination of the enantiomeric excess (2002) (55)
Study on the chiral recognition of the enantiomers of ephedrine derivatives with neutral and sulfated heptakis(2,3-O-diacetyl)-beta-cyclodextrins using capillary electrophoresis, UV, nuclear magnetic resonance spectroscopy and mass spectrometry. (2001) (54)
The Use of Self-organizing Neural Networks in Drug Design (2002) (50)
Identification of a [3H]Ligand for the common allosteric site of muscarinic acetylcholine M2 receptors. (1998) (50)
Atypical Muscarinic Allosteric Modulation: Cooperativity between Modulators and Their Atypical Binding Topology in Muscarinic M2 and M2/M5 Chimeric Receptors (2005) (50)
Allosteric Small Molecules Unveil a Role of an Extracellular E2/Transmembrane Helix 7 Junction for G Protein-coupled Receptor Activation* (2007) (49)
Chiral discrimination of phenethylamines with β-cyclodextrin and heptakis(2,3-di-O-acetyl)β-cyclodextrin by capillary electrophoresis and NMR spectroscopy (1994) (49)
Population Pharmacokinetic Comparison and Pharmacodynamic Breakpoints of Ceftazidime in Cystic Fibrosis Patients and Healthy Volunteers (2010) (48)
Search for dual function inhibitors for Alzheimer's disease: synthesis and biological activity of acetylcholinesterase inhibitors of pyridinium-type and their Abeta fibril formation inhibition capacity. (2006) (47)
Routine quality control of medicines in developing countries: Analytical challenges, regulatory infrastructures and the prevalence of counterfeit medicines in Tanzania (2016) (47)
Design, Synthesis and Evaluation of Novel 2‐(Aminoalkyl)‐isoindoline‐1,3‐dione Derivatives as Dual‐Binding Site Acetylcholinesterase Inhibitors (2012) (47)
Quantitative NMR spectroscopy of biologically active substances and excipients (2010) (47)
An LC-MS/MS procedure for the quantification of naproxen in human plasma: development, validation, comparison with other methods, and application to a pharmacokinetic study. (2011) (46)
Ficts and facts of epinephrine and norepinephrine stability in injectable solutions. (2012) (45)
Enantioseparation of dopa and related compounds by cyclodextrin-modified microemulsion electrokinetic chromatography. (2008) (45)
Dynamic ligand binding dictates partial agonism at a G protein-coupled receptor. (2014) (45)
Control of impurities in L-aspartic acid and L-alanine by high-performance liquid chromatography coupled with a corona charged aerosol detector. (2010) (44)
1H NMR profiling as an approach to differentiate conventionally and organically grown tomatoes. (2014) (44)
Composition of OSCS-contaminated heparin occurring in 2008 in batches on the German market. (2010) (43)
A Photoswitchable Dualsteric Ligand Controlling Receptor Efficacy. (2017) (43)
Fatty acid composition analysis in polysorbate 80 with high performance liquid chromatography coupled to charged aerosol detection. (2015) (43)
1H-NMR Spectroscopy as a New Tool in the Assessment of the Oxidative State in Edible Oils (2012) (43)
Analysis of atropine, its degradation products and related substances of natural origin by means of reversed-phase high-performance liquid chromatography. (2004) (42)
Pipecolic acid derivatives as small-molecule inhibitors of the Legionella MIP protein. (2011) (42)
Do we know the mechanism of chiral recognition between cyclodextrins and analytes? (2002) (42)
Interaction of (benzylidene-hydrazono)-1,4-dihydropyridines with beta-amyloid, acetylcholine, and butyrylcholine esterases. (2010) (41)
A cell-permeable inhibitor to trap Gαq proteins in the empty pocket conformation. (2014) (41)
The influence of fluoroquinolone drugs on the bacterial growth of S. epidermidis utilizing the unique potential of vibrational spectroscopy. (2007) (40)
Elevation of ligand binding to muscarinic M(2) acetylcholine receptors by bis(ammonio)alkane-type allosteric modulators. (2002) (40)
Determination of free fatty acids in pharmaceutical lipids by ¹H NMR and comparison with the classical acid value. (2014) (39)
Identification and control of impurities in streptomycin sulfate by high-performance liquid chromatography coupled with mass detection and corona charged-aerosol detection. (2011) (39)
Comparison of established and novel purity tests for the quality control of heparin by means of a set of 177 heparin samples (2011) (39)
Effect of β-cyclodextrin acetylation on the resolution of phenethylamines with capillary electrophoresis and nuclear magnetic resonance spectroscopy (1997) (38)
Predicting critical micelle concentration and micelle molecular weight of polysorbate 80 using compendial methods. (2015) (38)
Determination of the extent of protein binding of antibiotics by means of an automated continuous ultrafiltration method. (2006) (38)
Competitive inhibition of renal tubular secretion of ciprofloxacin and metabolite by probenecid. (2010) (38)
Structure-activity relationship and studies on the molecular mechanism of leishmanicidal N,C-coupled arylisoquinolinium salts. (2009) (38)
NMR Spectroscopic and Molecular Modelling Studies on Cyclodextrin–Dipeptide Inclusion Complexes (2005) (38)
Differentiation of Organically and Conventionally Grown Tomatoes by Chemometric Analysis of Combined Data from Proton Nuclear Magnetic Resonance and Mid-infrared Spectroscopy and Stable Isotope Analysis. (2015) (38)
Synthesis, Biological Activity, and Docking Studies of New Acetylcholinesterase Inhibitors of the Bispyridinium Type (2003) (38)
Resolution of ephedrine derivatives by means of neutral and sulfated heptakis(2,3‐di‐O‐acetyl)β‐cyclodextrins using capillary electrophoresis and nuclear magnetic resonance spectroscopy (1999) (38)
The insulinotropic effect of fluoroquinolones. (2009) (37)
The contamination of valsartan and other sartans, part 1: New findings. (2019) (36)
Search for the pharmacophore of bispyridinium-type allosteric modulators of muscarinic receptors. (1994) (36)
Capillary electrophoresis separation of phenethylamine enantiomers using amino acid based ionic liquids (2018) (36)
Determination of free fatty acids in edible oils by 1H NMR spectroscopy (2012) (36)
Chiral discrimination by NMR spectroscopy of ephedrine and N-methylephedrine induced by β-cyclodextrin, heptakis(2,3-di-O-acetyl)β-cyclodextrin, and heptakis (6-O-acetyl)β-cyclodextrin (1997) (35)
Chiral capillary electrophoresis: Facts and fiction on the reproducibility of resolution with randomly substituted cyclodextrins (2004) (35)
Enantioseparation of chiral tropa alkaloids by means of cyclodextrin‐modified microemulsion electrokinetic chromatography (2007) (35)
Structure/activity relationships of M2 muscarinic allosteric modulators. (2003) (35)
A new micellar electrokinetic capillary chromatography method for separation of the components of the aminoglycoside antibiotics (2003) (35)
Enantioseparation of dihydropyridine derivatives by means of neutral and negatively charged β‐cyclodextrin derivatives using capillary electrophoresis (2000) (34)
A small-molecule inhibitor of Nipah virus envelope protein-mediated membrane fusion. (2009) (34)
Analytical characterisation of crude extracts from an African Ancistrocladus species using high-performance liquid chromatography and capillary electrophoresis coupled to ion trap mass spectrometry. (2004) (33)
Use of evaporative light scattering detection for the quality control of drug substances: influence of different liquid chromatographic and evaporative light scattering detector parameters on the appearance of spike peaks. (2010) (33)
Comparison of Cyclodextrin‐Dipeptide Inclusion Complexes in the Absence and Presence of Urea by Means of Capillary Electrophoresis, Nuclear Magnetic Resonance and Molecular Modeling (2007) (33)
Comparison of chiral electrophoretic separation methods for phenethylamines and application on impurity analysis. (2010) (32)
Inhibition of flucloxacillin tubular renal secretion by piperacillin. (2008) (32)
Defluorinated Sparfloxacin as a New Photoproduct Identified by Liquid Chromatography Coupled with UV Detection and Tandem Mass Spectrometry (1998) (32)
Assignment of the major and minor components of gentamicin for evaluation of batches (2003) (32)
Synthesis and structure-activity relationships of new quinolone-type molecules against Trypanosoma brucei. (2012) (32)
Novel lead compounds in pre-clinical development against African sleeping sickness. (2017) (31)
Resolution of newly synthesized racemic dihydropyridines with different chiral selectors by means of capillary electrophoresis. (1999) (31)
Studies on the chiral recognition of peptide enantiomers by neutral and sulfated β‐cyclodextrin and heptakis‐(2,3‐di‐O‐acetyl)‐β‐cyclodextrin using capillary electrophoresis and nuclear magnetic resonance (2002) (31)
Ionic Liquid Versus Prodrug Strategy to Address Formulation Challenges (2015) (30)
Pentacyclic triterpenes from Cecropia telenitida with immunomodulatory activity on dendritic cells (2013) (30)
Determination of protein binding of gyrase inhibitors by means of continuous ultrafiltration. (1998) (30)
The role of solvents in the signal separation for quantitative (1)H NMR spectroscopy. (2010) (30)
Antitrypanosomal activity of quaternary naphthalimide derivatives. (2007) (30)
Synthesis and opioid receptor affinity of a series of 2, 4-diaryl-substituted 3,7-diazabicylononanones. (2000) (30)
Dualsteric muscarinic antagonists--orthosteric binding pose controls allosteric subtype selectivity. (2014) (30)
Determination of erythromycin and related substances in commercial samples using liquid chromatography/ion trap mass spectrometry. (2006) (30)
Bis(ammonio)alkane-type agonists of muscarinic acetylcholine receptors: synthesis, in vitro functional characterization, and in vivo evaluation of their analgesic activity. (2014) (30)
Penetration of Moxifloxacin into Bone Evaluated by Monte Carlo Simulation (2009) (30)
1,4-Substituted 4-(1H)-pyridylene-hydrazone-type inhibitors of AChE, BuChE, and amyloid-β aggregation crossing the blood-brain barrier. (2013) (29)
Focus on PAINS: false friends in the quest for selective anti-protozoal lead structures from Nature? (2016) (29)
Microwave-enhanced hydrogenations at medium pressure using a newly constructed reactor (2005) (29)
Rational design of partial agonists for the muscarinic m1 acetylcholine receptor. (2015) (29)
Mechanism of action of the diazabicyclononanone-type kappa-agonists. (2003) (29)
Population Pharmacokinetics of Piperacillin at Two Dose Levels: Influence of Nonlinear Pharmacokinetics on the Pharmacodynamic Profile (2012) (29)
Antileishmanial Lead Structures from Nature: Analysis of Structure-Activity Relationships of a Compound Library Derived from Caffeic Acid Bornyl Ester (2014) (28)
Antileishmanial and Cytotoxic Compounds from Valeriana wallichii and Identification of a Novel Nepetolactone Derivative † (2015) (28)
Evaluation of the stability of gentamicin in different antibiotic carriers using a validated MEKC method. (2008) (28)
1H NMR approach as an alternative to the classical p-anisidine value method (2012) (28)
Alternatives to amino acid analysis for the purity control of pharmaceutical grade L-alanine. (2010) (28)
Nonlinear pharmacokinetics of piperacillin in healthy volunteers--implications for optimal dosage regimens. (2010) (28)
HZ2, a Selective Kappa‐Opioid Agonist (1998) (27)
Optical Control of Cardiac Function with a Photoswitchable Muscarinic Agonist. (2019) (27)
Micellar electrokinetic capillary chromatography, high performance liquid chromatography and nuclear magnetic resonance--three orthogonal methods for characterization of critical drugs. (2004) (27)
Current role and future perspectives of multivariate (chemometric) methods in NMR spectroscopic analysis of pharmaceutical products. (2018) (27)
Conformational Analysis, Molecular Shape Comparison, and Pharmacophore Identification of Different Allosteric Modulators of Muscarinic Receptors (1996) (26)
Utilizing NMR spectroscopy for assessing drug enantiomeric composition (1998) (26)
Do we need new drugs against human African trypanosomiasis? (2013) (26)
Amino acid analysis for pharmacopoeial purposes. (2016) (26)
Bone Penetration of Amoxicillin and Clavulanic Acid Evaluated by Population Pharmacokinetics and Monte Carlo Simulation (2009) (26)
Identification and characterization of diarylimidazoles as hybrid inhibitors of butyrylcholinesterase and amyloid beta fibril formation. (2012) (26)
Impurity profiling of atropine sulfate by microemulsion electrokinetic chromatography. (2007) (25)
A systematic review of the stability of finished pharmaceutical products and drug substances beyond their labeled expiry dates (2019) (25)
Convergent, short synthesis of the muscarinic superagonist iperoxo (2010) (25)
Development of simplified HPLC methods for the detection of counterfeit antimalarials in resource-restraint environments. (2014) (24)
Anti-Schistosomal Activity of Cinnamic Acid Esters: Eugenyl and Thymyl Cinnamate Induce Cytoplasmic Vacuoles and Death in Schistosomula of Schistosoma mansoni (2015) (24)
Synthese, Stereochemie und analgetische Wirkung von 3,7‐Diazabicyclo[3.3.1]nonan‐9‐onen und 1,3‐Diazaadamantan‐6‐onen1) (1989) (24)
Systematic development of high affinity bis(ammonio)alkane-type allosteric enhancers of muscarinic ligand binding. (2003) (24)
In search of novel agents for therapy of tropical diseases and human immunodeficiency virus. (2008) (24)
1H, 19F and 13C NMR spectral data of fifteen gyrase inhibitors and some metabolites (1994) (23)
Stability and assessment of amino acids in parenteral nutrition solutions (2018) (23)
Fluorination of Photoswitchable Muscarinic Agonists Tunes Receptor Pharmacology and Photochromic Properties. (2019) (23)
Interlaboratory study of a NACE method for the determination of R‐timolol content in S‐timolol maleate: Assessment of uncertainty (2006) (23)
[In Citation]. (2006) (23)
New Semiphysiological Absorption Model To Assess the Pharmacodynamic Profile of Cefuroxime Axetil Using Nonparametric and Parametric Population Pharmacokinetics (2009) (23)
Bioinspired co‐crystals of Imatinib providing enhanced kinetic solubility (2018) (23)
Effects of fluoroquinolones on HERG channels and on pancreatic beta-cell ATP-sensitive K+ channels. (2006) (23)
Mapping the pharmaceutical design space by amorphous ionic liquid strategies (2017) (23)
NMR Spectroscopy in Drug Development and Analysis: Holzgrabe/NMR Spectroscopy (2007) (22)
Ligand-Specific Restriction of Extracellular Conformational Dynamics Constrains Signaling of the M2 Muscarinic Receptor. (2017) (22)
The contamination of valsartan and other sartans, Part 2: Untargeted screening reveals contamination with amides additionally to known nitrosamine impurities. (2019) (22)
Oxidative dehydrogenation of C–C and C–N bonds: A convenient approach to access diverse (dihydro)heteroaromatic compounds (2017) (22)
Pharmacological, Mechanistic, and Pharmacokinetic Assessment of Novel Melatonin-Tamoxifen Drug Conjugates as Breast Cancer Drugs (2019) (21)
Competitive Inhibition of Renal Tubular Secretion of Gemifloxacin by Probenecid (2009) (21)
Evaluation of amino sugar, low molecular peptide and amino acid impurities of biotechnologically produced amino acids by means of CE. (2002) (21)
Enantioseparation of tropa alkaloids by means of anionic cyclodextrin‐modified capillary electrophoresis (1999) (21)
Development of a new type of allosteric modulator of muscarinic receptors: hybrids of the antagonist AF-DX 384 and the hexamethonio derivative W84. (2004) (21)
M1 muscarinic cetylcholine receptor allosteric modulators as potential therapeutic opportunities for treating Alzheimer's disease (2012) (21)
Synthese und Stereochemie potentiell stark analgetischer 2,4‐m‐diarylsubstituierter 3,7‐Diazabicyclo[3.3.1]nonan‐9‐on‐1,5‐diester (1992) (21)
Quantification of taurine in energy drinks using ¹H NMR. (2014) (21)
Search for the Pharmacophore in Kappa‐agonistic Diazabicyclo[3.3.1]nonan‐9‐one‐1,5‐diesters and Arylacetamides (1996) (21)
Quantitative ¹H NMR analysis of egg yolk, alcohol, and total sugar content in egg liqueurs. (2015) (20)
Probing the size of a hydrophobic binding pocket within the allosteric site of muscarinic acetylcholine M2-receptors. (2000) (20)
Stereocontrolled synthesis of the enantiomers of 1-[2-hydroxy-3-(4-phenyl-1-piperazinyl)-propyl]-pyrrolidin-2-one (2001) (20)
Comparison of structurally different allosteric modulators of muscarinic receptors by self-organizing neural networks. (1996) (20)
Recent applications of the Charged Aerosol Detector for liquid chromatography in drug quality control. (2020) (20)
Evaluation of the impurity profile of amino acids by means of CE. (2001) (20)
Modeling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in Staphylococcus aureus, Staphylococcus epidermidis and human cells (2011) (20)
Fenton's oxidation: a tool for the investigation of potential drug metabolites. (2011) (20)
Inhibitors of macrophage infectivity potentiator-like PPIases affect neisserial and chlamydial pathogenicity. (2016) (19)
Allosteric effect on muscarinic M2-receptors of derivatives of the alkane-bis-ammonium compound W84: comparison with bispyridinium-type allosteric modulators (1994) (19)
Laser-induced fluorescence-capillary electrophoresis and fluorescence microplate reader measurement: two methods to quantify the effect of antibiotics. (2007) (18)
N-(3-Cyanophenyl)-2-phenylacetamide, an effective inhibitor of morbillivirus-induced membrane fusion with low cytotoxicity. (2010) (18)
Mode-of-Action Studies of the Novel Bisquaternary Bisnaphthalimide MT02 against Staphylococcus aureus (2010) (18)
Bisquaternary ligands of the common allosteric site of M2 acetylcholine receptors: search for the minimum essential distances between the pharmacophoric elements. (1999) (18)
Identification and quantitation of the ingredients in a counterfeit Vietnamese herbal medicine against rheumatic diseases. (2014) (18)
Designing Hybrids Targeting the Cholinergic System by Modulating the Muscarinic and Nicotinic Receptors: A Concept to Treat Alzheimer’s Disease (2018) (18)
Influence of charged aerosol detector instrument settings on the ultra-high-performance liquid chromatography analysis of fatty acids in polysorbate 80. (2018) (18)
Effect of various cyclodextrin derivatives on the resolution of fencamfamine isomers with capillary electrophoresis and nuclear magnetic resonance (1998) (18)
Muscarinic receptor agonists and antagonists (1999) (17)
Impurity profiling of carbocisteine by HPLC-CAD, qNMR and UV/vis spectroscopy. (2014) (17)
Antitrypanosomal naphthylisoquinoline alkaloids and related compounds. (2003) (17)
Quantitative 1H NMR spectroscopic determination of the E/Z isomer ratio of the antidepressant drug fluvoxamine for use in pharmaceutical analysis (2002) (17)
A New Bioactive Compound From the Marine Sponge-Derived Streptomyces sp. SBT348 Inhibits Staphylococcal Growth and Biofilm Formation (2018) (17)
Allosteric site in M2 acetylcholine receptors: evidence for a major conformational change upon binding of an orthosteric agonist instead of an antagonist (2005) (17)
Natural Products Repertoire of the Red Sea (2020) (16)
O-glycoside sequence of pentacyclic triterpene saponins from Phytolacca bogotensis using HPLC-ESI/multi-stage tandem mass spectrometry. (2009) (16)
Comparison of the pharmacokinetics and pharmacodynamic profile of carumonam in cystic fibrosis patients and healthy volunteers. (2009) (16)
The bisnaphthalimides as new active lead compounds against Plasmodium falciparum. (2010) (16)
Development of an enhanced separation of erythromycin and its related substances by liquid chromatography. (2007) (16)
Conformational and configurational behaviour of κ-agonistic 3,7-diazabicyclo[3.3.1]nonan-9-ones—synthesis, nuclear magnetic resonance studies and semiempirical PM3 calculations (1999) (16)
Piperidones with activity against Plasmodium falciparum (2006) (15)
New single-isomer chiral selector for capillary electrophoresis: the highly water-soluble heptakis(2-N,N-dimethylcarbamoyl)-beta-cyclodextrin. (2001) (15)
Future Information Technology Tools for Fighting Substandard and Falsified Medicines in Low- and Middle-Income Countries (2018) (15)
New insight into active muscarinic receptors with the novel radioagonist [³H]iperoxo. (2014) (15)
Geometrical and Structural Dynamics of Imatinib within Biorelevant Colloids. (2018) (15)
Determination of Oversulphated Chondroitin Sulphate and Dermatan Sulphate in unfractionated heparin by (1)H-NMR - Collaborative study for quantification and analytical determination of LoD. (2008) (15)
Cerulenin Analogues as Inhibitors of Efflux Pumps in Drug‐resistant Candida albicans (2009) (15)
1H and 13C nuclear magnetic resonance studies of the sites of protonation in itraconazole and fluconazole. (1999) (15)
Structurally novel group of ligands selective for kappa opioid receptors (1994) (15)
Overton's Rule Helps To Estimate the Penetration of Anti-Infectives into Patients' Cerebrospinal Fluid (2011) (14)
Synthesis, bioactivity and molecular modeling studies on potential anti-Alzheimer piperidinehydrazide-hydrazones. (2019) (14)
A Structural Biology Approach Enables the Development of Antimicrobials Targeting Bacterial Immunophilins (2013) (14)
Quantitation of talinolol and other β‐blockers by capillary electrophoresis for in vitro drug absorption studies (2003) (14)
Inhibition of hypusine biosynthesis in plasmodium: a possible, new strategy in prevention and therapy of malaria. (2006) (14)
Syntheses and Biological Activities of New N1‐Aryl Substituted Quinolone Antibacterials (1996) (14)
Synthesis and biological activity of pyridinium‐type acetylcholinesterase inhibitors (2003) (14)
N+/Si replacement as a tool for probing the pharmacophore of allosteric modulators of muscarinic M2 receptors: Synthesis, allosteric potency, and positive cooperativity of silicon-based W84 derivatives (2002) (14)
Tautomerism of 4-hydroxy-2,5-dimethyl-3(2H)-furanone: evidence for its enantioselective biosynthesis. (2003) (14)
RAL GTPases mediate multiple myeloma cell survival and are activated independently of oncogenic RAS. (2019) (13)
A New Molecular Mechanism To Engineer Protean Agonism at a G Protein–Coupled Receptor (2017) (13)
Comparison of Pharmacological Activities of Three Distinct (cid:1) Ligands (Salvinorin A, TRK-820 and 3FLB) on (cid:1) Opioid Receptors in Vitro and Their Antipruritic and Antinociceptive Activities in Vivo (2004) (13)
Critical aspects of analysis of Micrococcus luteus, Neisseria cinerea, and Pseudomonas fluorescens by means of capillary electrophoresis (2004) (13)
Cinnamic Acid Bornyl Ester Derivatives from Valeriana wallichii Exhibit Antileishmanial In Vivo Activity in Leishmania major-Infected BALB/c Mice (2015) (13)
Muscarinic allosteric enhancers of ligand binding: pivotal pharmacophoric elements in hexamethonio-type agents. (2005) (13)
Allosteric modulators and selective agonists of muscarinic receptors (2007) (13)
Absolute Quantitative 1H NMR Spectroscopy for Compound Purity Determination (2014) (13)
FRET Studies of Quinolone-Based Bitopic Ligands and Their Structural Analogues at the Muscarinic M1 Receptor. (2017) (13)
Comparable Population Pharmacokinetics and Pharmacodynamic Breakpoints of Cefpirome in Cystic Fibrosis Patients and Healthy Volunteers (2011) (13)
New Griselimycins for Treatment of Tuberculosis. (2015) (13)
Ligand-Specific Allosteric Coupling Controls G-Protein-Coupled Receptor Signaling. (2020) (13)
Profiling a gut microbiota-generated catechin metabolite's fate in human blood cells using a metabolomic approach. (2015) (13)
Protein release from electrospun nonwovens: improving the release characteristics through rational combination of polyester blend matrices with polidocanol. (2014) (12)
Multivariate analysis of nuclear magnetic resonance data--characterization of critical drug substance quality of gentamicin sulfate. (2005) (12)
Ugi Reaction-Derived α-Acyl Aminocarboxamides Bind to Phosphatidylinositol 3-Kinase-Related Kinases, Inhibit HSF1-Dependent Heat Shock Response, and Induce Apoptosis in Multiple Myeloma Cells. (2017) (12)
Bistacrine derivatives as new potent antimalarials. (2016) (12)
Impurity profiling of L-methionine by HPLC on a mixed mode column. (2016) (12)
A Stable and Highly Potent Hexamethonium Derivative Which Modulates Muscarinic Receptors Allosterically in Guinea‐pig Hearts (1994) (12)
Indirect Enantioseparation of Amino Acids by CE Using Automated In-Capillary Derivatization with ortho-Phthalaldehyde and N-Acetyl-l-Cysteine (2016) (12)
Quantitative liquid chromatography-mass spectrometry determination of isatin in urine using automated on-line extraction. (2002) (12)
Quinolone Amides as Antitrypanosomal Lead Compounds with In Vivo Activity (2016) (12)
Determination of clotrimazole in mice plasma by capillary electrophoresis. (2003) (12)
Isolation of a novel compound (MIMO2) from the methanolic extract of Moringa oleifera leaves: protective effects against vanadium-induced cytotoxity (2018) (12)
Diazabicyclo[3.3.1]nonanone‐type Ligands for the Opioid Receptors (2000) (12)
Capillary electrophoresis method for determination of related substances in glutathione reduced drug substance (2003) (12)
Amino acids: Aspects of impurity profiling by means of CE (2007) (12)
A new synthetic route to compounds of the AFDX-type with affinity to muscarinic M2-receptor (2003) (11)
Development and validation of a separation method for the diastereomers and enantiomers of aziridine‐type protease inhibitors (2005) (11)
Cer(IV)sulfat‐Oxidationen: Intramolekulare Cyclisierung von N‐Benzyl‐β‐aminoketonen zu 4‐Benzoyl‐1,2,3,4‐tetrahydroisochinolinen (1987) (11)
Ionic Liquids in Capillary Electrophoresis. (2016) (11)
Determination of plasma protein binding for sympathomimetic drugs by means of ultrafiltration (2019) (11)
Drug discovery: a modern decathlon. (2013) (11)
Online Monitoring of Microwave-Enhanced Reactions by UV/Vis Spectroscopy (2010) (11)
Lipophilicity and membrane interactions of cationic-amphiphilic compounds: syntheses and structure-property relationships. (2001) (10)
Muscarinic Allosteric Modulators: Atypical Structure‐Activity‐Relationships in Bispyridinium‐type Compounds (2006) (10)
Analysis of the molecular size distribution of polyethylene glycols by CE‐UV versus HPLC with evaporative light scattering detection (2008) (10)
Characterization of complexes between phenethylamine enantiomers and β‐cyclodextrin derivatives by capillary electrophoresis—Determination of binding constants and complex mobilities (2017) (10)
One-Pot Ugi/Aza-Michael Synthesis of Highly Substituted 2,5-Diketopiperazines with Anti-Proliferative Properties (2012) (10)
Quantitative structure-property relationship modeling of polar analytes lacking UV chromophores to charged aerosol detector response (2019) (10)
Qualitative and quantitative 1H NMR spectroscopy for determination of divalent metal cation concentration in model salt solutions, food supplements, and pharmaceutical products by using EDTA as chelating agent (2020) (10)
Novel bipharmacophoric inhibitors of the cholinesterases with affinity to the muscarinic receptors M1 and M2. (2017) (10)
Neuroprotective Effects of Isosteviol Sodium in Murine Brain Capillary Cerebellar Endothelial Cells (cerebEND) After Hypoxia (2020) (10)
Semisynthetic Analogues of Toxiferine I and Their Pharmacological Properties at α7 nAChRs, Muscle-Type nAChRs, and the Allosteric Binding Site of Muscarinic M2 Receptors (2014) (10)
Improving anti-trypanosomal activity of alkamides isolated from Achillea fragrantissima. (2017) (10)
Impurity profiling of ibandronate sodium by HPLC-CAD. (2015) (10)
A Novel Mechanism of Inactivating Antibacterial Nitro Compounds in the Human Pathogen Staphylococcus aureus by Overexpression of a NADH-Dependent Flavin Nitroreductase (2017) (10)
Evaluation of enantiomeric purity of magnesium-L-aspartate dihydrate. (2015) (10)
Novel Population Pharmacokinetic Approach to Explain the Differences between Cystic Fibrosis Patients and Healthy Volunteers via Protein Binding (2019) (10)
Real time observation of microwave-enhanced reactions via fast FTIR spectroscopy (2009) (9)
Studies on the stereochemistry of 1,2,6-trimethyl-4-piperidone (2005) (9)
Reduktionen an 3,7‐Diazabicyclo[3.3.1]nonan‐9‐onen und 1,3‐Diazaadamantan‐6‐onen1) (1989) (9)
Targeting protein folding; a novel approach for the treatment of pathogenic bacteria. (2020) (9)
Validation and application of an HPLC-CAD-TOF/MS method for identification and quantification of pharmaceutical counterions. (2014) (9)
A diversity oriented synthesis of natural product inspired molecular libraries. (2017) (9)
Quantitative NMR Spectroscopy in Pharmaceutical R&D (2015) (9)
Capillary zone electrophoresis as a tool for the quality control of goldenseal extracts (2005) (9)
Ein photoschaltbarer Ligand zur Regulierung der Rezeptoraktivierung (2017) (9)
Impurity profile of amino acids? (2005) (9)
1H NMR analytical characterization of mineral oil hydrocarbons (PARAFFINS) for pharmaceutical use (2019) (9)
Formation of a 1,6-Naphthyridine Derivative by a Double Mannich Reaction. (1998) (9)
Regulatory framework in Pakistan: situation analysis of medicine quality and future recommendations (2019) (9)
1H and 19F NMR relaxation studies of fleroxacin with Micrococcus luteus. (2007) (9)
Development, synthesis and structure-activity-relationships of inhibitors of the macrophage infectivity potentiator (Mip) proteins of Legionella pneumophila and Burkholderia pseudomallei. (2016) (8)
Tyrosinase Inhibition Type of Isolated Compounds Obtained from Pachyrhizus erosus (2013) (8)
Contribution of lateral substituents in heptane-bisammonium derivatives to the allosteric stabilization of antagonist binding to M2-receptors. (1997) (8)
Alte Wege zu neuen Antibiotika – Platensimycin (2006) (8)
Prediction of the oversulphated chondroitin sulphate contamination of unfractionated heparin by ATR-IR spectrophotometry. (2009) (8)
Determination of the Enantiomeric Purity by Means of NMR Spectroscopy and Capillary Electrophoresis Using a Heptakis(2,3-di-O-acetyl)-β-cyclodextrin: A Comparison. (1999) (8)
Synthesis, X-ray analysis and spectroscopic characterization of the hemiaminal cyclization product from 2,4-dipyridine substituted 3,7-diazabicyclo[3.3.1]nonanone 1,5-diesters (1999) (8)
Power function setting in charged aerosol detection for the linearization of detector response - optimization strategies and their application. (2020) (8)
Random chemistry as a new tool for the generation of small compound libraries: development of a new acetylcholinesterase inhibitor. (2005) (8)
The nitrosamine contamination of drugs, part 3: Quantification of 4-Methyl-1-nitrosopiperazine in rifampicin capsules by LC-MS/HRMS. (2021) (8)
Meropenem–Clavulanate: A New Strategy for the Treatment of Tuberculosis? (2009) (8)
Quality of the antimalarial medicine artemether - lumefantrine in 8 cities of the Democratic Republic of the Congo. (2018) (8)
Fluorine walk: The impact of fluorine in quinolone amides on their activity against African sleeping sickness. (2018) (8)
A miniaturized peptidyl-prolyl isomerase enzyme assay. (2017) (8)
Analysis of Drugs (2007) (8)
Tacrine-xanomeline and tacrine-iperoxo hybrid ligands: Synthesis and biological evaluation at acetylcholinesterase and M1 muscarinic acetylcholine receptors. (2020) (8)
Capillary zone electrophoresis for the determination of amodiaquine and three of its synthetic impurities in pharmaceutical formulations (2018) (7)
High-performance liquid chromatography evaluation of the enantiomeric purity of amino acids by means of automated precolumn derivatization with ortho-phthalaldehyde and chiral thiols. (2016) (7)
Additional therapy with mistletoe extracts in breast cancer patients receiving chemotherapy - a prospective randomized open label pilot study. (2009) (7)
Capillary electrophoretic resolution of the enantiomers of 2,5-dimethyl-4-hydroxy-3(2H)-furanone, the key flavor compounds in strawberry fruit (2003) (7)
Enantioseparation of chiral thiobarbiturates using cyclodextrin‐modified capillary electrophoresis (2001) (7)
Comparison of the separation of aziridine isomers applying heptakis(2,3‐di‐O‐methyl‐6‐sulfato)β‐CD and heptakis(2,3‐di‐O‐acetyl‐6‐sulfato)β‐CD in aqueous and nonaqueous systems (2005) (7)
Stabilization of delphinidin in a complex with sulfobutylether-β-cyclodextrin allows for antinociception in inflammatory pain. (2020) (7)
Bisquaternary dimers of strychnine and brucine. A new class of potent enhancers of antagonist binding to muscarinic M2 receptors. (2003) (7)
Ligands for the common allosteric site of acetylcholine M2-receptors: development and application. (2000) (7)
Quantitative Analysis in Pharmaceutical Analysis (2009) (7)
Anti-trypanosomal activities and structural chemical properties of selected compound classes (2015) (7)
Cer(IV)‐Oxidationen von β‐Aminoketonen. 3. Mitt.: Ein Syntheseweg zu 4‐spirosubstituierten 1,2,3,4‐Tetrahydroisochinolinen (1988) (7)
Characterization of polydisperse macrogols and macrogol‐based excipients via HPLC and charged aerosol detection (2018) (7)
Diazabicyclononanones, a potent class of kappa opioid analgesics. (2002) (7)
The influence of Osmunda regalis root extract on head and neck cancer cell proliferation, invasion and gene expression (2017) (7)
Characterization of paromomycin sulfate by capillary electrophoresis with UV detection after pre-capillary derivatization (2002) (7)
Structure–Activity Relationships of Strychnine Analogs at Glycine Receptors (2014) (7)
Stereochemistry and opioid receptor affinity of 2,4‐dipyridine‐3,7‐diazabicyclo[3.3.1]nonanones ‐ influence of the substituent in position N7 (2002) (6)
Indoles XIV. 4-Phenylpyrido[4,3-b]indoles and 5-Phenylazepino[4,5-b]indoles by Cyclisation of N-Indolylalkyl-ephedrine Derivatives — Scope and Stereoselectivity (2001) (6)
Hexamethonium‐Type Allosteric Modulators of the Muscarinic Receptors Bearing Lateral Dibenzazepine Moieties (2001) (6)
Protein binding in a congeneric series of antibacterial quinolone derivatives (1998) (6)
Influence of the capillary diameter on the separation efficiency and sensitivity: A systematic approach (2012) (6)
Von Penicillin G zu tricyclischen β‐Lactamen: Struktur‐Wirkungs‐Beziehungen (2006) (6)
Opioid-agonisten und -antagonisten, opioid-rezeptoren (1997) (6)
Molekulare Allianz – von orthosterischen und allosterischen Liganden zu dualsterischen/bitopischen Agonisten G‐Protein‐gekoppelter Rezeptoren (2013) (6)
Interlaboratory Comparison Test as an Evaluation of Applicability of an Alternative Edible Oil Analysis by 1H NMR Spectroscopy. (2017) (6)
Design, Synthesis and Evaluation of Novel 2‐(Aminoalkyl)isoindoline‐1,3‐dione Derivatives as Dual‐Binding Site Acetylcholinesterase Inhibitors. (2012) (6)
Variation of the oxime function of bispyridinium-type allosteric modulators of M2-cholinoceptors. (1995) (6)
Quantitative NMR spectroscopy—principles and applications (2005) (6)
Impurity profiling of N,N'-ethylenebis-l-cysteine diethyl ester (Bicisate). (2018) (6)
Quantitative NMR, Methods and Applications (2010) (6)
A Fast and Efficient Track to Allosteric Modulators of Muscarinic Receptors: Microwave-Assisted Syntheses (2007) (6)
Aqueous Two‐Phase Partitioning ‐ Physical Chemistry and Bioanalytical Applications. Boris Y. Zaslavlsky, 656 Seiten, Marcel Dekker Inc. New York 1995, 195.00 $, ISBN 0–8247–9461 (1995) (6)
Enhanced Fluorescence Resonance Energy Transfer in G-Protein-Coupled Receptor Probes on Nanocoated Microscopy Coverslips (2018) (6)
Impurity profiling of l-aspartic acid and glycine using high-performance liquid chromatography coupled with charged aerosol and ultraviolet detection. (2020) (6)
Cerium(IV)oxidations, Part IX: Cyclization of Diethyl 4‐Phenylbutane‐1, 1‐dicarboxylate (1993) (6)
Risk assessment report of potential impurities in cetirizine dihydrochloride. (2020) (6)
Evaluation of the impurity profile of alcuronium by means of capillary electrophoresis. (2002) (6)
Enantioseparation of linear and cyclic chiral bis(phenethyl)amines by means of cyclodextrin-modified capillary electrophoresis (2001) (6)
Glycerolipid Composition and Advanced Physicochemical Considerations of Sacha Inchi Oil toward Cosmetic Products Formulation (2019) (5)
Kappa-receptor selective binding of opioid ligands with a heterocyclic bicyclo[3.3.1]nonan-9-one structure. (2003) (5)
Structure–Effect Relationships of Novel Semi-Synthetic Cannabinoid Derivatives (2019) (5)
Charged aerosol detector response modeling for fatty acids based on experimental settings and molecular features: a machine learning approach (2021) (5)
Oxime Ethers of (E)-11-Isonitrosostrychnine as Highly Potent Glycine Receptor Antagonists. (2016) (5)
Azathioprine-induced reversible EBV-associated Hodgkin-like lymphoma after immunosuppressive therapy for autoimmune hepatitis . (2018) (5)
Development of a simple, rapid, and robust liquid chromatographic method for the simultaneous determination of sulfalene, sulfadoxine, and pyrimethamine in tablets. (2016) (5)
Cooperative Interactions at M2 Muscarinic Acetylcholine Receptors: Structure/Activity Relationships in Stepwise Shortened Bispyridinium- and Bis(Ammonio)Alkane-Type Allosteric Modulators (2003) (5)
Tracing the origin of paracetamol tablets by near-infrared, mid-infrared, and nuclear magnetic resonance spectroscopy using principal component analysis and linear discriminant analysis (2021) (5)
qNMR Spectroscopy in Drug Analysis – A General View (2008) (5)
Comparison of extraction efficiency and selectivity between low‐temperature pressurized microwave‐assisted extraction and prolonged maceration (2020) (5)
Quantification of Bisoprolol and Metoprolol in Simultaneous Human Serum and Cerebrospinal Fluid Samples (2017) (5)
Controlling Supramolecular Structures of Drugs by Light. (2020) (5)
Development and validation of a generic stability‐indicating MEEKC method for five fluoroquinolone antibiotics (2015) (5)
A stability-study of expired ampoules manufactured more than 40 years ago. (2018) (5)
Bioinspired Ion Pairs Transforming Papaverine into a Protic Ionic Liquid and Salts (2020) (5)
Comparison of Conventional and Microwave Assisted Reactions Giving Aromatic Oxazolidines (2003) (5)
11 The need for CE methods in pharmacopoeial monographs (2008) (5)
Paclitaxel zur Alzheimer‐Behandlung (2005) (5)
Cer(IV)oxidationen von β‐Aminoketonen, 8. Mitt.: Synthese von im Piperidinteil verschieden substituierten 1,2,3,4‐Tetrahydroisochinolinen (1993) (5)
Investigation of tryptophan-related yellowing in parenteral amino acid solution: Development of a stability-indicating method and assessment of degradation products in pharmaceutical formulations. (2020) (5)
Simple and rapid high performance liquid chromatography method for the determination of polidocanol as bulk product and in pharmaceutical polymer matrices using charged aerosol detection. (2015) (5)
Welche berufsbezeichnung wird Ehrlichs Wirken gerecht (2004) (5)
NMR spectroscopy in pharmaceutical and biomedical analysis. (2014) (5)
Impurity profiling of l-asparagine monohydrate by ion pair chromatography applying low wavelength UV detection. (2016) (5)
First population pharmacokinetic analysis showing increased quinolone metabolite formation and clearance in patients with cystic fibrosis compared to healthy volunteers (2018) (5)
pH‐Dependent NMR Measurements (2007) (4)
Anti-bacterial anacardic acid derivatives. (2020) (4)
Quality and composition of Albendazole, Mebendazole and Praziquantel available in Burkina Faso, Côte d’Ivoire, Ghana and Tanzania (2021) (4)
The ameliorative effects of a phenolic derivative of Moringa oleifera leave against vanadium-induced neurotoxicity in mice (2020) (4)
The Role of Orthosteric Building Blocks of Bitopic Ligands for Muscarinic M1 Receptors (2020) (4)
[Plectasin - a new peptide antibiotic with high therapeutic potential]. (2010) (4)
A long-time stability study of 50 drug substances representing common drug classes of pharmaceutical use. (2019) (4)
Opening NADPH oxidase inhibitors for in vivo translation (2017) (4)
Matrix-assisted laser desorption/ionization tandem mass spectrometry of N-glycans derivatized with isonicotinic hydrazide and its biotinylated form. (2014) (4)
Possibilities and limitations of capillary electropherosis in pharmaceutical analysis. (2013) (4)
NMR Spectroscopy: Determination of Peroxide Value in Vegetable and Krill Oil by Using Triphenylphosphine as Tagging Reagent (2020) (4)
Neue Wirkstoffe in der Entwicklung: Wohin geht die Chinolonreise? (2001) (4)
Quantification of Hydrochlorothiazide and Ramipril/Ramiprilate in Blood Serum and Cerebrospinal Fluid: A Pharmacokinetic Assessment of Central Nervous System Adverse Effects (2018) (4)
Evaluation of the extent of protein binding by means of NMR diffusion and relaxation experiments, and automated continuous ultrafiltration. (2009) (4)
[New 4-quinolone derivatives in review]. (1999) (4)
Significance of capillary electrophoresis in the pharmaceutical industry (2005) (4)
P79 dependence of the potency of bisquaternary allosteric modulators of M2-cholinoceptors on the length of the central alkyl chain (1994) (4)
Agonists with supraphysiological efficacy at the muscarinic M 2 acetylcholine receptor 1 Running title : Supraphysiological M 2 receptor activation (2012) (4)
On the over-additive antimuscarinic action with atropine of potent allosteric stabilizers of antagonist binding to M2-receptors (1993) (4)
Supportive care in pancreatic carcinoma patients treated with a fermented mistletoe (Viscum album L.) extract. (2009) (4)
Engineered Context-Sensitive Agonism: Tissue-Selective Drug Signaling through a G Protein-Coupled Receptor (2017) (4)
Stereochemistry of 2,6-Dipyridine Substituted N-Benzyl-4-piperidone Mono- and Dicarboxylates and of the Corresponding Reduction Products (1989) (4)
Reproducibility challenges in the search for antibacterial compounds from nature (2021) (4)
Pharmakokinetik und Pharmakodynamik von Antibiotika in der Intensivmedizin (2017) (4)
Cer(IV)oxidationen von β‐Aminoketonen, 6. Mitt.: Untersuchungen zum Reaktionsverlauf (1989) (4)
Anticancer effects of NSC‑631570 (Ukrain) in head and neck cancer cells: In vitro analysis of growth, invasion, angiogenesis and gene expression. (2019) (4)
Stereochemical behaviour of κ-agonistic 2,4-dipyridin-2-yl-3,7-diazabicyclo[3.3.1]nonanones—influence of the substituent in position N3 (2001) (4)
Cer(IV)‐Oxidationen von β‐Aminoketonen. Teil IV: Synthese isomerer Phenanthridinone Cerium(IV) (1988) (4)
Bistacrines as potential antitrypanosomal agents. (2017) (4)
Neue Antibiotika: Den Vorsprung gegenüber resistenten Bakterien wahren (2009) (4)
A Sequence of Aldol Condensations and a Michael Addition Giving a Cyclohexenone Ring System (2001) (4)
Synthesis and Opioid Receptor Affinity of a Series of 2,4-Diaryl-Substituted 3,7-Diazabicyclononanones. (2001) (4)
Synthesis and evaluation of antitrypanosomal activity of some thiosemicarbazide derivatives of 1-butyl-6-fluoro-7-morpholino-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (2018) (4)
Tamper-proof tablets for distinction between counterfeit and originator drugs through PEG coding. (2016) (4)
Long-lasting cytotoxic effects of a single application of aqueous extracts from dried Viscum album L. on bladder cancer cells in an in vitro system. (2009) (4)
Cyclodextrin-mediated enantioseparation in microemulsion electrokinetic chromatography. (2013) (3)
Comparable Bioavailability and Disposition of Pefloxacin in Patients with Cystic Fibrosis and Healthy Volunteers Assessed via Population Pharmacokinetics (2019) (3)
Cer(IV)oxidationen von β–Aminoketonen. 7. Mitt.: Synthese von 4‐Benzoylisochinolin und des davon abgeleiteten Lactams (1988) (3)
Impurity profiling of dapsone using gradient HPLC method. (2021) (3)
Performance of ion pairing chromatography and hydrophilic interaction liquid chromatography coupled to charged aerosol detection for the analysis of underivatized amino acids. (2021) (3)
Diffusion ordered NMR spectroscopy measurements as screening method of potential reactions of API and excipients in drug formulations (2019) (3)
Cer(IV) Oxidationen, 10. Mitt.: Oxidation von ω‐Phenylalkyldicarbonyl‐ und dicarbonyl‐analogen Verbindungen (1994) (3)
Serjanic Acid Improves Immunometabolic Markers in a Diet-Induced Obesity Mouse Model (2020) (3)
Assessment of inhibitory potency of antibiotics by MRI: apparent T2 as a marker of cell growth (2006) (3)
Investigation of isomerization of dexibuprofen in a ball mill using chiral capillary electrophoresis (2021) (3)
Severe Drug-Induced Liver Injury as an Adverse Drug Event of Antibiotics: A Case Report and Review of the Literature (2017) (3)
11-Aminostrychnine and N-(Strychnine-11-yl)propionamide: Synthesis, Configuration, and Pharmacological Evaluation at Glycine Receptors. (2019) (3)
A New Synthetic Approach to Pentacyclic Ring, 6,7,14,15-Tetrahydro[1,5]diazocino[1,2-a:6,5-a’]-8-dihydrodiindole (2011) (3)
Viscotoxin and mistletoe lectin contents in Viscum album L. - pharmaceutical implications. (2009) (3)
Synthesis and Nucleophilic Reactions of Cyano Substituted N‐Methoxyisoquinolinium Salts (1993) (3)
Crystal structure of (3S*,4R*)-4-fluoro-3-(4-methoxyphenyl)-1-oxo-2-phenyl-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid (2017) (3)
Batch variability of bacitracin: HPLC versus MEKC. (2005) (3)
Investigation of Multi-Component Drugs by NMR Spectroscopy (2008) (3)
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Counterfeit Drugs Studied by NMR (2017) (3)
Use of collision induced dissociation mass spectrometry as a rapid technique for the identification of pharmacologically active peptides in pharmacopoeial testing. (2011) (3)
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Die neue Karriere des Thalidomids. Ein altes Schlafmittel als Cancerostatikum (2007) (2)
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Population Pharmacokinetics and Pharmacodynamics of Piperacillin : Systematic Comparison of Cystic Fibrosis Patients and Healthy Volunteers (2007) (2)
E–Z isomerism of anilinomethylenemalonic acid derivatives (1993) (2)
Complexation Behavior of Drugs Studied by NMR (2007) (2)
Microwave-Enhanced Hydrogenations at Medium Pressure Using a Newly Constructed Reactor. (2005) (2)
[Lactivicin--an antibiotic against penicillin-resistant pneumococci]. (2007) (2)
Comparison of Pantoprazole Concentrations in Simultaneous Cerebrospinal Fluid and Serum Samples (2016) (2)
Tissue level profile of SARS-CoV-2 antivirals in mice to predict their effects in COVID-19 multiorgan failure (2020) (2)
Distinguishing paracetamol formulations: Comparison of potentiometric "Electronic Tongue" with established analytical techniques. (2020) (2)
4-[(2E)-2-(4-Chlorobenzylidene)hydrazinylidene]-1-methyl-1,4-dihydropyridine monohydrate (2010) (2)
Impurity Control in Topiramate with High Performance Liquid Chromatography (2017) (2)
Zwitterionic‐hydrophilic interaction liquid chromatography for l‐ascorbic acid 2‐phosphate magnesium, a raw material in cell therapy (2019) (2)
Synthesis and X-Ray Analysis of the (S) Enantiomer of Methyl 5-Hydroxy-3,11-di-2-pyridyl-4,5-dihydro-1H,3H-2,6-methano- 6-benz[c]azocinecarboxylate C24H23N3O3 and of the Corresponding Camphanic Acid Ester C34H35N3O6 (1988) (2)
Verunreinigung von Arzneistoffen (2003) (2)
Keto-Enol-Tautomerism and Configurational Isomerism of 2,6-Disubstituted 4-Piperidone-3,5-dicarboxylates (1991) (2)
Impurity Profiling of Baclofen Using Gradient HPLC–UV Method (2021) (2)
The importance of the primary dosage in mistletoe therapy. (2009) (2)
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A New Compound (8,9) -Furanyl-Pterocarpan-3-Ol Used for Standardization of Bengkuang (Pachyrhizus erosus) Extract as Sunscreen and Skin Whitening Agent (2019) (2)
A comprehensive study on retention of selected model substances in β-cyclodextrin-modified high performance liquid chromatography. (2021) (2)
Structure-activity relationships in a series of bisquaternary bisphthalimidine derivatives modulating the muscarinic M(2)-receptor allosterically. (2000) (2)
1H and 13C NMR studies of substituted isoquinolinium derivatives in different solvents (1992) (2)
Allosteric Modulators of the Tertiary Alkanebisamino-Type. Variation of the Substitution of the Middle Chain Nitrogens (2004) (2)
Stereoselektive Synthese tertiärer 2,6‐Methano‐2‐benzazocin‐5‐ole (1990) (2)
Lactivicin – ein Antibiotikum gegen Penicillin‐resistente Pneumokokken (2007) (2)
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Influence of the mobile phase composition on hyphenated ultraviolet and charged aerosol detection for the impurity profiling of vigabatrin. (2021) (2)
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Isolation and Characterization of Galloylglucoses Effective against Multidrug-Resistant Strains of Escherichia coli and Klebsiella pneumoniae (2022) (2)
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Conformational Analysis, Molecular Shape Comparison, and Pharmacophore Identification of Different Allosteric Modulators of Muscarinic Receptors. (1997) (1)
Contribution of Lateral Substituents in Symmetrical and Non‐symmetrical Heptane‐bisammonio Compounds to the Allosteric Stabilization of N‐methylscopolamine Binding to Muscarinic M2 Receptors (2003) (1)
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Simultaneous Determination of the Saponification Value, Acid Value, Ester Value, and Iodine Value in Commercially Available Red Fruit Oil (Pandanus conoideus, Lam.) Using 1H qNMR Spectroscopy (2022) (1)
A Convenient Preparation of Carboxy-γ-pyrone Derivatives: Meconic Acid and Comenic Acid (2018) (1)
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Corona Charged Aerosol Detector in studying retention and β-cyclodextrin complex stability using RP-HPLC. (2020) (1)
Impurity Profiling of Bisoprolol Fumarate by Liquid Chromatography-High-Resolution Mass Spectrometry: A Combination of Targeted and Untargeted Approaches using a Synthesis Reaction Matrix and General Unknown Comparative Screening (2021) (1)
Photocatalyzed [2 + 2 + 2]‐Cycloaddition of Nitriles with Acetylene: An Effective Method for the Synthesis of 2‐Pyridines under Mild Conditions. (2002) (1)
β‐Lactam‐Antibiotika als Neuroprotektoren (2006) (1)
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Crystal structure of 5,11-dihydropyrido[2,3-b][1,4]benzodiazepin-6-one (2015) (1)
Enantioseparation by Capillary Electrophoresis Using Cyclodextrins in an Amino Acid-Based Ionic Liquid Running Buffer. (2019) (1)
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Efficacy and risk estimation of subcutaneous mistletoe treatment (Viscum album L. Pini) in patients with non-Hodgkin's Lymphoma, a retrospective controlled case study. (2009) (1)
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C-2-Linked Dimeric Strychnine Analogues as Bivalent Ligands Targeting Glycine Receptors. (2021) (1)
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Zwei Fliegen mit einer Klappe – Platencin, ein neues Antibiotikum (2007) (0)
Neue Wege zu hoch wirksamen Tetracyclinen (2005) (0)
Nuclear Imaging in Drugs Discovery, Development, and Approval Herausgeber: H. D. Burns, R. E. Gibson, R. F. Dannals und P. K. Siegel, Birkhäuser, Boston 1993, 339 Seiten, Hardcover, 132,— DM, ISBN 0‐8176‐3601‐3 und ISBN 3‐7643‐3601‐3 (1993) (0)
Wie wirkt Paracetamol? Ein weiterer Mosaikstein zum Wirkmechismus (2006) (0)
Micellar electrokinetic chromatography of aminoglycosides. (2008) (0)
[Perfect drug targeting. Glufosfamide a new derivative]. (2006) (0)
Editorial: Pharmazie in unserer Zeit 2/2006 (2006) (0)
Alternative Wege zu “Multidrug”‐resistenten Bakterien via reaktiver Sauerstoffspezies (2010) (0)
Distributionswege: Wie stabil sind Arzneimittel (2004) (0)
[Editorial: Pharmazie in unserer Zeit 6/2009 ]. (2009) (0)
Die Entwicklung selektiver α2‐Rezeptor‐Agonisten (2011) (0)
Influenza und Co : Tödliche Bedrohung durch Viren (2005) (0)
Ketolide und Oxazolidinone in der Pipeline: Und die Reise geht weiter… (2004) (0)
Kleine Änderung, große Wirkung – ein neues Vancomycin‐Derivat gegen MRSA (2006) (0)
3-(2-Chloropyridin-3-yl)quinazoline-2,4(1H,3H)-dione chloroform monosolvate (2017) (0)
Editorial: Pharmazie in unserer Zeit 2/2005 (2005) (0)
Inhibition von Virulenzfaktoren: Ein neuer Ansatz zur Entwicklung von Antibiotika (2006) (0)
XF-73 – eine neue antibakterielle Leitstruktur (2010) (0)
Antibiotics and Antiviral Compounds — Chemical Synthesis and Modification. Hrsg.: K. Krohn, H. A. Krohn, H. Maag. 482 Seiten, 128,— DM, ISBN 3—527—29040—0 (VCH, Weinheim), 1—56081—743—3 (VCH, New York) VCH Weinheim, 1993 (1994) (0)
Paradigmenwechsel vom Sondersammelgebiet zum Fachinformationsdienst Pharmazie. Kommentar aus Nutzerinnen-Perspektive (2018) (0)
Aqueous mistletoe preparations with a high content of oleanolic acid and betulinic acid. (2009) (0)
Editorial: Pharmazie in unserer Zeit 6/2005 (2005) (0)
Zweifach-Angriff auf die Gyrase durch Simocyclinon (2010) (0)
Oral verfügbarer Fusionshemmstoff gefunden (2005) (0)
Die Fettsäuresynthese als Angriffspunkt (2012) (0)
Zwei Fliegen mit einer Klappe – Platencin, ein neues Antibiotikum (2007) (0)
Grußwort der Präsidentin (2004) (0)
Bio oder nicht – lassen sich die Produkte durch 1H-NMR-Spektroskopie unterscheiden? (2015) (0)
Assessment of the Performance of an NMR Assay for the Determination of Hydroperoxides in Lipids (2011) (0)
[How a formula should be presented in a book]. (2001) (0)
Editorial: Pharmazie in unserer Zeit 1/2004 (2004) (0)
Statement. DPhG fordert eine zeitnahe Aktualisierung von Fachinformationen zur Vermeidung von Arzneimittelinteraktionen (2006) (0)
Vitamin E. Alles ist im Fluss (2009) (0)
Neue Wege zu selektiven Antiinfektiva (2005) (0)
Grußwort: Pharmazie in unserer Zeit 1/2005 (2005) (0)
[Helping ourselves to promote our scientific advancement]. (2008) (0)
Design, synthesis and biological evaluations of quinolone amides against African trypanosomiasis with improved solubility. (2023) (0)
Molecular modeling of bispyridinium oxime derivatives with allosteric effects on M2-cholinoceptors (1994) (0)
Allosteric Modulators of the Tertiary Alkanebisamino-Type. Variation of the Substitution of the Middle Chain Nitrogens. (2005) (0)
Stereochemistry and Opioid Receptor Affinity of 2,4-Dipyridine-3,7-diazabicyclo[3.3.1]nonanones — Influence of the Substituent in Position N7. (2002) (0)
[Inhibitors of the New Delhi-Metallolactamase]. (2012) (0)
Epidemiological data from the Network Oncology, a research association for anthroposophically oriented medicine. (2009) (0)
[Small change, large effect--a new vancomycin derivative against MRSA]. (2006) (0)
[Return to the pre-Semmelweis-age - MRSA, NDM-1 and what is to come?]. (2010) (0)
β-Lactams and Related Compounds as Antibacterials and β-Lactamase Inhibitors (2020) (0)
Natur häufig Vorbild (2016) (0)
A Novel Class of Allosteric Modulators of the Muscarinic M2 Acetylcholine Receptor: Terphenyl Derivatives (2003) (0)
antiinfectives into patientscerebrospinal fluid (2011) (0)
Crystal structure of 1,1 -(1,3-propanediyl)bis(4-cyano)pyridiniuiii dibromide, [NC-C5H4N-C3H6-NC5H4-CN]Br2 (1997) (0)
[Where are quinolones going? New agents in development]. (2001) (0)
[RANTES protein protects monkeys from infection with chimeric AIDS viruses]. (2005) (0)
[New antibiotics in sight?]. (2009) (0)
[A new weapon against beta-3 lactamases?]. (2006) (0)
[HIV therapy: and an even newer treatment--PA-457]. (2004) (0)
Correlation between distinct immune parameters, tumour staging and quality of life. (2009) (0)
[Problem of counterfeit medicines in Africa and Southeast Asia. Fake anti-malaria drugs and more]. (2009) (0)
New Antiepileptica: An Overview (1997) (0)

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What Schools Are Affiliated With Ulrike Holzgrabe?

Ulrike Holzgrabe is affiliated with the following schools: