Umesh Varshney
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Indian molecular biologist, academician and the head of the Prof.Umesh Varshney's Lab at the Indian Institute of Science, Bengaluru
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Umesh Varshneybiology Degrees
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Biology Chemistry
Umesh Varshney's Degrees
- Masters Biochemistry Delhi University
- Bachelors Chemistry Delhi University
Why Is Umesh Varshney Influential?
(Suggest an Edit or Addition)According to Wikipedia, Umesh Varshney is an Indian molecular biologist, academician and the head of a laboratory at the Indian Institute of Science, Bengaluru. He is a J. C. Bose National Fellow of the Department of Science and Technology and is known for his studies on protein synthesis and DNA repair in Escherichia coli and Mycobacterium tuberculosis. An elected fellow of the Indian Academy of Sciences, Indian National Science Academy and the National Academy of Sciences , he is also a recipient of the National Bioscience Award for Career Development of the Government of India. The Council of Scientific and Industrial Research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2001, and then in 2014 with the G. N. Ramachandran Gold Medal for Excellence in Biological Sciences & Technology for his contributions to biological sciences.
Umesh Varshney's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Direct analysis of aminoacylation levels of tRNAs in vivo. Application to studying recognition of Escherichia coli initiator tRNA mutants by glutaminyl-tRNA synthetase. (1991) (379)
- Initiation of protein synthesis from a termination codon. (1990) (108)
- A single mammalian mitochondrial translation initiation factor functionally replaces two bacterial factors. (2008) (95)
- Peptidyl-tRNA hydrolase and its critical role in protein biosynthesis. (2006) (90)
- Sequence analysis, expression, and conservation of Escherichia coli uracil DNA glycosylase and its gene (ung). (1988) (89)
- Specific interaction between the ribosome recycling factor and the elongation factor G from Mycobacterium tuberculosis mediates peptidyl‐tRNA release and ribosome recycling in Escherichia coli (2001) (89)
- Chimeras between Single-stranded DNA-binding Proteins fromEscherichia coli and Mycobacterium tuberculosisReveal That Their C-terminal Domains Interact with Uracil DNA Glycosylases* (2001) (80)
- Role of the central metal ion and ligand charge in the DNA binding and modification by metallosalen complexes. (1997) (78)
- Specificities and kinetics of uracil excision from uracil-containing DNA oligomers by Escherichia coli uracil DNA glycosylase. (1991) (77)
- Structure, organization, and regulation of human metallothionein IF gene: differential and cell-type-specific expression in response to heavy metals and glucocorticoids (1986) (71)
- Structure of Mycobacterium tuberculosis single-stranded DNA-binding protein. Variability in quaternary structure and its implications. (2003) (69)
- From elongator tRNA to initiator tRNA. (1993) (69)
- Importance of Uracil DNA Glycosylase in Pseudomonas aeruginosa and Mycobacterium smegmatis, G+C-rich Bacteria, in Mutation Prevention, Tolerance to Acidified Nitrite, and Endurance in Mouse Macrophages* (2003) (67)
- Role of 16S ribosomal RNA methylations in translation initiation in Escherichia coli (2008) (67)
- Mutants of initiator tRNA that function both as initiators and elongators. (1991) (66)
- Import of amber and ochre suppressor tRNAs into mammalian cells: A general approach to site-specific insertion of amino acid analogues into proteins (2001) (65)
- A physiological connection between tmRNA and peptidyl-tRNA hydrolase functions in Escherichia coli. (2004) (61)
- Structural plasticity and enzyme action: crystal structures of mycobacterium tuberculosis peptidyl-tRNA hydrolase. (2007) (58)
- Development of a New Generation of Vectors for Gene Expression, Gene Replacement, and Protein-Protein Interaction Studies in Mycobacteria (2013) (56)
- A distinct role of formamidopyrimidine DNA glycosylase (MutM) in down-regulation of accumulation of G, C mutations and protection against oxidative stress in mycobacteria. (2007) (53)
- X-ray analysis of a complex of Escherichia coli uracil DNA glycosylase (EcUDG) with a proteinaceous inhibitor. The structure elucidation of a prokaryotic UDG. (1998) (53)
- Crystal structure of Rv2118c: an AdoMet-dependent methyltransferase from Mycobacterium tuberculosis H37Rv. (2001) (51)
- Role of methionine and formylation of initiator tRNA in initiation of protein synthesis in Escherichia coli (1992) (47)
- Genetic Analysis Identifies a Function for the queC (ybaX) Gene Product at an Initial Step in the Queuosine Biosynthetic Pathway in Escherichia coli (2005) (47)
- Unique features of the structure and interactions of mycobacterial uracil-DNA glycosylase: structure of a complex of the Mycobacterium tuberculosis enzyme in comparison with those from other sources. (2008) (46)
- Striking effects of coupling mutations in the acceptor stem on recognition of tRNAs by Escherichia coli Met-tRNA synthetase and Met-tRNA transformylase. (1992) (45)
- Structure and expression of the human metallothionein-IG gene. Differential promoter activity of two linked metallothionein-I genes in response to heavy metals. (1988) (45)
- Metal-ion-dependent oxidative DNA cleavage by transition metal complexes of a new water-soluble salen derivative. (1996) (44)
- A distinct physiological role of MutY in mutation prevention in mycobacteria. (2010) (40)
- Recycling of ribosomal complexes stalled at the step of elongation in Escherichia coli. (2008) (39)
- Important role of the nucleotide excision repair pathway in Mycobacterium smegmatis in conferring protection against commonly encountered DNA-damaging agents. (2008) (39)
- Biochemical properties of single-stranded DNA-binding protein from Mycobacterium smegmatis, a fast-growing mycobacterium and its physical and functional interaction with uracil DNA glycosylases. (2002) (37)
- Initiator tRNA and its role in initiation of protein synthesis. (2001) (37)
- Base excision and nucleotide excision repair pathways in mycobacteria. (2011) (37)
- The IDL of E. coli SSB links ssDNA and protein binding by mediating protein–protein interactions (2017) (37)
- Cloning, over-expression and biochemical characterization of the single-stranded DNA binding protein from Mycobacterium tuberculosis. (1999) (37)
- MIC and Upper Limit of Wild-Type Distribution for 13 Antifungal Agents against a Trichophyton mentagrophytes-Trichophyton interdigitale Complex of Indian Origin (2020) (36)
- X-ray structural studies of Mycobacterium tuberculosis RRF and a comparative study of RRFs of known structure. Molecular plasticity and biological implications. (2005) (36)
- Substrate specificities and functional characterization of a thermo-tolerant uracil DNA glycosylase (UdgB) from Mycobacterium tuberculosis. (2007) (36)
- Interaction of Hoechst 33258 with repeating synthetic DNA polymers and natural DNA. (1988) (35)
- The Role of Leucine 191 of Escherichia coliUracil DNA Glycosylase in the Formation of a Highly Stable Complex with the Substrate Mimic, Ugi, and in Uracil Excision from the Synthetic Substrates* (2001) (35)
- Impact of rRNA methylations on ribosome recycling and fidelity of initiation in Escherichia coli (2009) (34)
- Use of Mycobacterium smegmatis Deficient in ADP-Ribosyltransferase as Surrogate for Mycobacterium tuberculosis in Drug Testing and Mutation Analysis (2015) (33)
- Evidence for a role of initiation factor 3 in recycling of ribosomal complexes stalled on mRNAs in Escherichia coli (2005) (33)
- A unique uracil-DNA binding protein of the uracil DNA glycosylase superfamily (2015) (33)
- Mycobacterium tuberculosis Rv2118c codes for a single-component homotetrameric m1A58 tRNA methyltransferase. (2004) (31)
- Mutations that alter the regulation of the chb operon of Escherichia coli allow utilization of cellobiose (2007) (31)
- One-Carbon Metabolic Pathway Rewiring in Escherichia coli Reveals an Evolutionary Advantage of 10-Formyltetrahydrofolate Synthetase (Fhs) in Survival under Hypoxia (2014) (30)
- An evolutionarily conserved element in initiator tRNAs prompts ultimate steps in ribosome maturation (2016) (30)
- Crucial contribution of the multiple copies of the initiator tRNA genes in the fidelity of tRNAfMet selection on the ribosomal P-site in Escherichia coli (2010) (30)
- Synergistic effects of UdgB and Ung in mutation prevention and protection against commonly encountered DNA damaging agents in Mycobacterium smegmatis. (2010) (30)
- Uracil DNA glycosylase from Mycobacterium smegmatis and its distinct biochemical properties. (1998) (30)
- Human metallothionein MT-I and MT-II processed genes. (1984) (30)
- Mycobacterium tuberculosis MutT1 (Rv2985) and ADPRase (Rv1700) Proteins Constitute a Two-stage Mechanism of 8-Oxo-dGTP and 8-Oxo-GTP Detoxification and Adenosine to Cytidine Mutation Avoidance* (2013) (29)
- Distinct mechanisms of DNA repair in mycobacteria and their implications in attenuation of the pathogen growth (2012) (29)
- SIRT6 transcriptionally regulates global protein synthesis through transcription factor Sp1 independent of its deacetylase activity (2019) (28)
- Unconventional initiator tRNAs sustain Escherichia coli (2012) (28)
- Distamycin Analogues without Leading Amide at Their N‐Termini − Comparative Binding Properties to AT‐ and GC‐Rich DNA Sequences (2002) (28)
- Differential effects of single-stranded DNA binding proteins (SSBs) on uracil DNA glycosylases (UDGs) from Escherichia coli and mycobacteria. (1999) (28)
- Covalent binding of uracil DNA glycosylase UdgX to abasic DNA upon uracil excision (2019) (28)
- Contrasting effects of single stranded DNA binding protein on the activity of uracil DNA glycosylase from Escherichia coli towards different DNA substrates. (1997) (28)
- Biochemical Properties of MutT2 Proteins from Mycobacterium tuberculosis and M. smegmatis and Their Contrasting Antimutator Roles in Escherichia coli (2013) (28)
- Distinctive contributions of the ribosomal P-site elements m2G966, m5C967 and the C-terminal tail of the S9 protein in the fidelity of initiation of translation in Escherichia coli (2013) (27)
- Effects of mutations at tyrosine 66 and asparagine 123 in the active site pocket of Escherichia coli uracil DNA glycosylase on uracil excision from synthetic DNA oligomers: evidence for the occurrence of long-range interactions between the enzyme and substrate. (2002) (25)
- Characterization of Mycobacterium tuberculosis ribosome recycling factor (RRF) and a mutant lacking six amino acids from the C-terminal end reveals that the C-terminal residues are important for its occupancy on the ribosome. (2002) (24)
- Important Role of the Amino Acid Attached to tRNA in Formylation and in Initiation of Protein Synthesis in Escherichia coli(*) (1996) (24)
- Inefficient excision of uracil from loop regions of DNA oligomers by E. coli uracil DNA glycosylase. (1994) (23)
- Characterization of the initiator tRNA gene locus and identification of a strong promoter from Mycobacterium tuberculosis. (1997) (22)
- Two highly conserved features of bacterial initiator tRNAs license them to pass through distinct checkpoints in translation initiation (2016) (22)
- Domain closure and action of uracil DNA glycosylase (UDG): structures of new crystal forms containing the Escherichia coli enzyme and a comparative study of the known structures involving UDG. (2002) (21)
- Common Location of Determinants in Initiator Transfer RNAs for Initiator-Elongator Discrimination in Bacteria and in Eukaryotes* (2003) (21)
- Evolution of initiator tRNAs and selection of methionine as the initiating amino acid (2016) (20)
- Uracil excision repair in Mycobacterium tuberculosis cell-free extracts. (2011) (20)
- How Many Initiator tRNA Genes Does Escherichia coli Need? (2014) (20)
- Awareness and Practices about Bio-medical waste among Health care workers in Tertiary care hospital of Haldwani, Nainital - (2015) (20)
- Complexes of the uracil-DNA glycosylase inhibitor protein, Ugi, with Mycobacterium smegmatis and Mycobacterium tuberculosis uracil-DNA glycosylases. (2003) (20)
- Mechanism of recycling of post-termination ribosomal complexes in eubacteria: A new role of initiation factor 3 (2006) (19)
- Contributions of the N- and C-Terminal Domains of Initiation Factor 3 to Its Functions in the Fidelity of Initiation and Antiassociation of the Ribosomal Subunits (2017) (18)
- An unexpected absence of queuosine modification in the tRNAs of an Escherichia coli B strain. (2002) (18)
- Role of the Ribosomal P-Site Elements of m2G966, m5C967, and the S9 C-Terminal Tail in Maintenance of the Reading Frame during Translational Elongation in Escherichia coli (2013) (18)
- Distinct properties of Mycobacterium tuberculosis single-stranded DNA binding protein and its functional characterization in Escherichia coli. (2000) (17)
- Initiation with Elongator tRNAs (2013) (17)
- Detrimental Effects of Hypoxia-Specific Expression of Uracil DNA Glycosylase (Ung) in Mycobacterium smegmatis (2010) (17)
- Hijacking Translation Initiation for Synthetic Biology (2020) (16)
- Analysis of the fusA2 locus encoding EFG2 in Mycobacterium smegmatis. (2009) (16)
- Use of a coupled transcriptional system for consistent overexpression and purification of UDG-Ugi complex and Ugi from Escherichia coli. (1998) (16)
- Crystal Structure of Rv 2118 c : An AdoMet-dependent Methyltransferase from Mycobacterium tuberculosis H 37 Rv (16)
- Mouse hepatic metallothionein-I gene cleavage by micrococcal nuclease is enhanced after induction by cadmium. (1983) (15)
- Novel insertion and deletion mutants of RpoB that render Mycobacterium smegmatis RNA polymerase resistant to rifampicin-mediated inhibition of transcription. (2010) (14)
- Mycobacterium tuberculosis and Escherichia coli nucleoside diphosphate kinases lack multifunctional activities to process uracil containing DNA. (2004) (14)
- Diet-dependent depletion of queuosine in tRNAs in Caenorhabditis elegans does not lead to a developmental block (2007) (13)
- Biochemical and structural studies of Mycobacterium smegmatis MutT1, a sanitization enzyme with unusual modes of association. (2017) (13)
- An extended Shine–Dalgarno sequence in mRNA functionally bypasses a vital defect in initiator tRNA (2014) (13)
- Mutational analysis of the uracil DNA glycosylase inhibitor protein and its interaction with Escherichia coli uracil DNA glycosylase. (2002) (13)
- Paralogous cAMP receptor proteins in Mycobacterium smegmatis show biochemical and functional divergence. (2014) (13)
- Compromised base excision repair pathway in Mycobacterium tuberculosis imparts superior adaptability in the host (2021) (12)
- Structural basis for uracil DNA glycosylase interaction with uracil: NMR study. (2000) (12)
- A frequent restriction fragment length polymorphism in the human metallothionein-II processed gene region is evolutionarily conserved. (1984) (12)
- Structural plasticity in Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) and its functional implications. (2015) (12)
- Impact of Mutating the Key Residues of a Bifunctional 5,10-Methylenetetrahydrofolate Dehydrogenase-Cyclohydrolase from Escherichia coli on Its Activities. (2015) (11)
- Structural characterisation of a uracil containing hairpin DNA by NMR and molecular dynamics. (1999) (11)
- Rapid and reliable site-directed mutagenesis using Kunkel's approach. (1998) (10)
- Structure of uracil-DNA glycosylase from Mycobacterium tuberculosis: insights into interactions with ligands. (2010) (10)
- Human metallothionein-II processed gene is located in region p11----q21 of chromosome 4. (1985) (10)
- Intragenic suppression in tRNA: evidence for crosstalk between the D and the T stems. (1997) (10)
- Analysis of the initiator tRNA genes from a slow- and a fast-growing mycobacterium (2002) (9)
- Regulation of translation by one-carbon metabolism in bacteria and eukaryotic organelles (2020) (9)
- Fidelity of translation in the presence of mammalian mitochondrial initiation factor 3. (2017) (9)
- Hydrolysis of diadenosine polyphosphates. Exploration of an additional role of Mycobacterium smegmatis MutT1. (2017) (9)
- Diverse roles of nucleoside diphosphate kinase in genome stability and growth fitness (2020) (9)
- Structure and expression of the human metallothionein genes. (1987) (9)
- Translation initiation in mammalian mitochondria- a prokaryotic perspective (2019) (8)
- The Termination Phase in Protein Synthesis is not Obligatorily Followed by the RRF/EF-G-Dependent Recycling Phase. (2016) (8)
- Distinct properties of a hypoxia specific paralog of single stranded DNA binding (SSB) protein in mycobacteria. (2018) (8)
- Monomeric NADH-Oxidizing Methylenetetrahydrofolate Reductases from Mycobacterium smegmatis Lack Flavin Coenzyme (2020) (8)
- Analysis of the impact of a uracil DNA glycosylase attenuated in AP-DNA binding in maintenance of the genomic integrity in Escherichia coli (2010) (8)
- Characterization of the ung1 mutation of Escherichia coli. (1989) (8)
- Uracil DNA glycosylase (UDG) activities in Bradyrhizobium diazoefficiens: characterization of a new class of UDG with broad substrate specificity (2017) (8)
- Hypersensitivity of hypoxia grown Mycobacterium smegmatis to DNA damaging agents: Implications of the DNA repair deficiencies in attenuation of mycobacteria (2013) (7)
- Sustenance of Escherichia coli on a single tRNAMet (2018) (7)
- Diagnostic validation of IgM and IgG ELISA and real-time PCR in detecting scrub typhus infection in endemic regions (2018) (7)
- Structure of the second Single Stranded DNA Binding protein (SSBb) from Mycobacterium smegmatis. (2016) (7)
- Acquisition of a stable mutation in metY allows efficient initiation from an amber codon in Escherichia coli. (2005) (6)
- Overexpression, purification, crystallization and preliminary X-ray analysis of uracil N-glycosylase from Mycobacterium tuberculosis in complex with a proteinaceous inhibitor. (2006) (6)
- Mycobacterium tuberculosis Rv 2118 c codes for a single-component homotetrameric m 1 A 58 tRNA methyltransferase (6)
- Substitutions at tyrosine 66 of Escherichia coli uracil DNA glycosylase lead to characterization of an efficient enzyme that is recalcitrant to product inhibition. (2003) (6)
- Chimeras of Escherichia coli and Mycobacterium tuberculosis Single-Stranded DNA Binding Proteins: Characterization and Function in Escherichia coli (2011) (6)
- Rapid formylation of the cellular initiator tRNA population makes a crucial contribution to its exclusive participation at the step of initiation (2019) (6)
- Is the cellular initiation of translation an exclusive property of the initiator tRNAs? (2015) (6)
- Cloning, expression, purification, crystallization and preliminary X-ray analysis of peptidyl-tRNA hydrolase from Mycobacterium tuberculosis. (2006) (6)
- Development of mCherry tagged UdgX as a highly sensitive molecular probe for specific detection of uracils in DNA. (2019) (6)
- Recycling of the posttermination complexes of Mycobacterium smegmatis and Escherichia coli ribosomes using heterologous factors. (2010) (5)
- Unusual DNA Binding Exhibited by Synthetic Distamycin Analogues Lacking the N-terminal Amide Unit under High Salt Conditions (2001) (5)
- Rewiring of one carbon metabolism in Salmonella serves as an excellent live vaccine against systemic salmonellosis. (2018) (5)
- Promoter analysis in mycobacteria using xyIE reporter assays and its implication in high throughput screening. (2001) (5)
- Functional Significance of an Evolutionarily Conserved Alanine (GCA) Resume Codon in tmRNA in Escherichia coli (2011) (5)
- Structures of new crystal forms of Mycobacterium tuberculosis peptidyl-tRNA hydrolase and functionally important plasticity of the molecule. (2012) (5)
- The Mere Lack of rT Modification in Initiator tRNA Does Not Facilitate Formylation-Independent Initiation inEscherichia coli (2001) (5)
- Crystallization and preliminary X-ray studies of the single-stranded DNA-binding protein from Mycobacterium tuberculosis. (2002) (5)
- Base excision repair pathways of bacteria: new promise for an old problem. (2020) (5)
- Coevolution of the translational machinery optimizes initiation with unusual initiator tRNAs and initiation codons in mycoplasmas (2018) (5)
- Species-Specific Interactions of Arr with RplK Mediate Stringent Response in Bacteria (2018) (4)
- A mutation in the ribosomal protein uS12 reveals novel functions of its universally conserved PNSA loop (2020) (4)
- Utilisation of 10-formyldihydrofolate as substrate by dihydrofolate reductase (DHFR) and 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) tranformylase/IMP cyclohydrolase (PurH) in Escherichia coli. (2018) (4)
- Physiological role of FolD (methylenetetrahydrofolate dehydrogenase), FchA (methenyltetrahydrofolate cyclohydrolase) and Fhs (formyltetrahydrofolate synthetase) from Clostridium perfringens in a heterologous model of Escherichia coli. (2016) (4)
- Epidemiological, clinical and laboratory profile of scrub typhus cases detected by serology and RT-PCR in Kumaon, Uttarakhand: a hospital-based study (2018) (4)
- Contrasting effects of mutating active site residues, aspartic acid 64 and histidine 187 of Escherichia coli uracil-DNA glycosylase on uracil excision and interaction with an inhibitor protein. (2002) (4)
- Salmonella Typhimurium outer membrane protein A (OmpA) renders protection against nitrosative stress by promoting SCV stability in murine macrophages (2021) (4)
- Salmonella Typhimurium outer membrane protein A (OmpA) renders protection from nitrosative stress of macrophages by maintaining the stability of bacterial outer membrane (2022) (4)
- Development of Assay Systems for Amber Codon Decoding at the Steps of Initiation and Elongation in Mycobacteria (2018) (3)
- Purification, crystallization and preliminary X-ray studies of Mycobacterium tuberculosis RRF. (2004) (3)
- Structural basis for poor uracil excision from hairpin DNA. An NMR study. (2002) (3)
- CRYSTAL STRUCTURE OF AN ADOMET DEPENDENT METHYLTRANSFERASE (2001) (3)
- Molecular flexibility of Mycobacterium tuberculosis ribosome recycling factor and its functional consequences: An exploration involving mutants (2013) (3)
- Linear free-energy model description of the conformational stability of uracil-DNA glycosylase inhibitor A thermodynamic characterization of interaction with denaturant and cold denaturation. (2001) (3)
- Avoiding acidic region streaking in two-dimensional gel electrophoresis: Case study with two bacterial whole cell protein extracts (2014) (3)
- A Genetic Analysis of the Functional Interactions within Mycobacterium tuberculosis Single-Stranded DNA Binding Protein (2014) (3)
- Excision of uracil from the ends of double stranded DNA by uracil DNA glycosylase and its use in high efficiency cloning of PCR products (1994) (3)
- Nucleoside Diphosphate Kinase Escalates A-to-C Mutations in MutT-Deficient Strains of Escherichia coli (2019) (3)
- Use of a molecular beacon based fluorescent method for assaying uracil DNA glycosylase (Ung) activity and inhibitor screening (2021) (3)
- ESCHERICHIA COLI URACIL-DNA GLYCOSYLASE (2002) (3)
- Metabolic flux of N10-formyltetrahydrofolate plays a critical role in the fidelity of translation initiation in Escherichia coli. (2020) (3)
- Crystallization and preliminary X-ray studies of MutT1 (MSMEG_2390) from Mycobacterium smegmatis. (2012) (3)
- NOBEL PRIZE FOR MEDICINE OR PHYSIOLOGY (1994) (3)
- Systematic evolution of initiation factor 3 and the ribosomal protein uS12 optimizes Escherichia coli growth with an unconventional initiator tRNA (2021) (2)
- A rare case of genital myiasis in a woman with psychiatric disturbance (2017) (2)
- Crowding, molecular volume and plasticity: An assessment involving crystallography, NMR and simulations (2012) (2)
- Crystallization and preliminary X-ray characterization of MutT2, MSMEG_5148 from Mycobacterium smegmatis. (2014) (2)
- Antimicrobial activity of fusidic acid in Escherichia coli is dependent on the relative levels of ribosome recycling factor and elongation factor G (2018) (2)
- Organization and copy number of initiator tRNA genes in slow- and fast-growing mycobacteria (1998) (2)
- Inosine incorporation in GC rich RNA probes increases hybridization sequence specificity. (1988) (2)
- The history that brought it all alive (2006) (2)
- The ribosome and the 2009 Nobel Prize in Chemistry (2010) (2)
- Crystal structure of Peptidyl-tRNA hydrolase from Mycobacterium tuberculosis (2007) (2)
- G4 DNA present at human telomeric DNA contributes toward reduced sensitivity to γ-radiation induced oxidative damage, but not bulky adduct formation (2021) (2)
- Use of sequence microdivergence in mycobacterial ortholog to analyze contributions of the water-activating loop histidine of Escherichia coli uracil-DNA glycosylase in reactant binding and catalysis. (2004) (2)
- Simultaneous presence of fhs and purT genes is disadvantageous for the fitness of Escherichia coli growth. (2015) (2)
- Rapid and reliable site directed mutagenesis using Kunkel's approach. (1998) (2)
- Two highly conserved features of bacterial initiator tRNAs license them to pass through distinct checkpoints in translation initiation. (2016) (1)
- An alternative role of RluD in the fidelity of translation initiation in Escherichia coli. (2022) (1)
- Role of The Two Highly Conserved Features of Initiator tRNAs in Initiation of Protein Synthesis in Eubacteria (2018) (1)
- Role of the nucleotide excision repair pathway proteins (UvrB and UvrD2) in recycling UdgB, a base excision repair enzyme in Mycobacterium smegmatis. (2022) (1)
- Identification of a new and diverse set of Mycobacterium tuberculosstais uracil-DNA glycosylase (MtUng) inhibitors using structure-based virtual screening: experimental validation and molecular dynamics studies. (2022) (1)
- Regulation of translation by one-carbon metabolism in bacteria and eukaryotic organelles. (2020) (1)
- Fosfomycin versus Nitrofurantoin for the Treatment of Lower UTI in Outpatients (2021) (1)
- Structural insights into the specificity and catalytic mechanism of mycobacterial nucleotide pool sanitizing enzyme MutT2. (2018) (1)
- Make science an attractive career (2015) (1)
- SOLUTION STRUCTURE OF A URACIL CONTAINING HAIRPIN DNA (2000) (0)
- GWAS and functional studies implicate a role for altered DNA repair in the evolution of drug resistance in Mycobacterium tuberculosis (2022) (0)
- Structural insights into the catalysis mechanism of M. smegmatis antimutator protein MutT2 (2019) (0)
- Correction for Kapoor et al., “Functional Significance of an Evolutionarily Conserved Alanine (GCA) Resume Codon in tmRNA in Escherichia coli” (2019) (0)
- Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase in complex with uracil, Form III (2015) (0)
- DNA Repair in Mycobacteria (2016) (0)
- Crystal structure of the single-stranded dna-binding protein from mycobacterium tuberculosis (2004) (0)
- Identity of a Prokaryotic Initiator tRNA (1993) (0)
- E52Q mutant form of Uracil DNA glycosylase X from Mycobacterium smegmatis. (2019) (0)
- Methionyl-tRNA formyltransferase utilizes 10-formyldihydrofolate as an alternative substrate and impacts antifolate drug action. (2023) (0)
- from mycobacteria and Escherichia coli : mechanism of urad ! excision from synthetic substrates and differential interaction with uracil DNA glycosy ~ lase inhibitor ( Ugi ) and single stranded DNA binding proteins ( SSBs ) (2013) (0)
- Structure of selenomethionine-labelled Uracil DNA glycosylase (BdiUNG) from Bradyrhizobium diazoefficiens (2017) (0)
- Crystal structure of Mycobacterium smegmatis MutT1 in complex with 8-oxo-dGTP (2020) (0)
- Diverse roles of nucleoside diphosphate kinase in genome stability and growth fitness (2020) (0)
- H109S mutant form of Uracil DNA glycosylase X. (2019) (0)
- Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase in complex with 2-thiouracil, Form V (2015) (0)
- Structure of Mycobacterium tuberculosis ribosome recycling factor in presence of detergent (2014) (0)
- Mutations in the transcriptional regulator ChbR that allow cellobiose utilization in E.coli (2006) (0)
- Structure, Organization, andRegulation ofHumanMetallothionein IFGene:Differential andCell-Type-Specif (1986) (0)
- Peptidyl-tRNA hydrolase from Mycobacterium tuberculosis from trigonal partially dehydrated crystal (2012) (0)
- Crystal structure of uracil-DNA glycosylase from Mycobacterium tuberculosis (2010) (0)
- Characterization of a second Single Stranded DNA Binding protein from Mycobacterium smegmatis (2017) (0)
- Crowding, molecular volume and plasticity: An assessment involving crystallography, NMR and simulations (2012) (0)
- Crystal structure of Mycobacterium smegmatis MutT1 (2017) (0)
- Crystal structure of Mycobacterium smegmatis MutT1 in complex with ATP (II) (2017) (0)
- Structural and Functional Studies on Uracil DNA Glycosylase from Bradyrhizobium japonicum (2016) (0)
- Structural Basis for Poor Excision from Hairpin DNA: NMR Study (2002) (0)
- Role of the insertion region in mammalian mitochondrial initiation factor 2 in translational initiation (2007) (0)
- Crystal structure of Mycobacterium smegmatis MutT1 in complex with 8-oxo-dGDP (2017) (0)
- M. smegmatis antimutator protein MutT2 in complex with 5mdCTP (2019) (0)
- M. smegmatis antimutator protein MutT2 form 3 (2019) (0)
- Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase in complex with 5-fluorouracil (AB), Form II (2015) (0)
- Crystal structure of Mycobacterium smegmatis MutT1 in complex with GMPPNP (GDP) (2020) (0)
- Interaction Studies in Mycobacteria Replacement, and Protein-Protein Vectors for Gene Expression, Gene Development of a New Generation of (2013) (0)
- Crystal structure of Uracil DNA glycosylase -Xanthine complex from Bradyrhizobium diazoefficiens (2017) (0)
- Crystal structure of Mycobacterium smegmatis MutT1 in complex with GMPPCP (GDP) (2020) (0)
- Contributory presentations/posters (1999) (0)
- Contributory presentations/posters (1999) (0)
- Complex form of Uracil DNA glycosylase X and uracil (2019) (0)
- Research activities of the Centre for Genetic Engineering (2013) (0)
- Complex form of Uracil DNA glycosylase X and uracil-DNA. (2019) (0)
- (tRNA identity switch/methionine tRNA/glutamine tRNA/formylation/ribosomal P site) (2016) (0)
- Crystal structure of Mycobacterium smegmatis MutT1 in complex with Ap5A, ATP and magnesium (2017) (0)
- Abstract 3802: A novel uracil-DNA glycosylase, UdgX, as a new biochemical tool to directly detect uracils in DNA (2017) (0)
- P 18 Structural studies on M . smegmatis MutT 2 , a sanitization enzyme (2017) (0)
- Crystal structure of C-terminal deletion mutant of ribosome recycling factor from Mycobacterium tuberculosis (2014) (0)
- Complex form of Uracil DNA glycosylase X and deoxyuridine monophosphate. (2019) (0)
- Umesh Escherichia coli Need ? How Many Initiator tRNA Genes Does (2014) (0)
- Crystal structure of Mycobacterium smegmatis MutT1 in complex with ATP, magnesium fluoride and phosphate (2017) (0)
- The initiation factor 3 (IF3) residues interacting with initiator tRNA elbow modulate the fidelity of translation initiation and growth fitness in Escherichia coli (2022) (0)
- Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase, Form IV (2015) (0)
- Antimutator Roles in Escherichia coli smegmatis and Their Contrasting from Mycobacterium tuberculosis and M . Biochemical Properties of MutT 2 Proteins (2013) (0)
- ESCHERICHIA COLI URACIL-DNA GLYCOSYLASE COMPLEX WITH URACIL-DNA GLYCOSYLASE INHIBITOR PROTEIN (2002) (0)
- Crystal structures of Peptidyl-tRNA hydrolase from Mycobacterium tuberculosis - Form 2 grown in presence of Pentaglycine (2012) (0)
- Structural studies on M. smegmatis MutT2, a sanitization enzyme (2017) (0)
- Crystal structure of Uracil DNA glycosylase (BdiUNG) from Bradyrhizobium diazoefficiens (2017) (0)
- Crystal structure of Ribosome recycling factor from Mycobacterium Tuberculosis (2005) (0)
- Plasticity, ligand conformation and enzyme action of Mycobacterium smegmatis MutT1. (2020) (0)
- Structural variability of Mycobacterium tuberculosis SSB and susceptibility to inhibition (2022) (0)
- Crystal structure of Mycobacterium smegmatis MutT1 in complex with phosphate and magnesium ions (excess magnesium, II) (2017) (0)
- Nudix hydrolases with Coenzyme A (CoA) and acyl-CoA pyrophosphatase activities confer growth advantage to Mycobacterium smegmatis. (2019) (0)
- Front Cover: Hijacking Translation Initiation for Synthetic Biology (ChemBioChem 10/2020) (2020) (0)
- Foreword - The history that brought it all alive (2006) (0)
- Structural Analysis of Ligand Bound Complex of UdgX (2016) (0)
- GWAS and functional studies suggest a role for altered DNA repair in the evolution of drug resistance in Mycobacterium tuberculosis (2023) (0)
- M. smegmatis antimutator protein MutT2 in complex with dCMP (2019) (0)
- M. smegmatis antimutator protein MutT2 in complex with 5m-dCMP (2019) (0)
- Role of the Two Highly Conserved Features of Initiator tRNAs in the Initiation of Proteins and Synthesis in Eubacteria (2018) (0)
- 1999 XIII International Biophysics Congress 19-24 September 1999 New Delhi Abstracts Suppl (2016) (0)
- Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase in complex with 6-aminouracil, Form IV (2015) (0)
- Crystal structure of Mycobacterium smegmatis MutT1 in complex with 8-oxo-dGTP, 8-oxo-dGMP and pyrophosphate (II) (2017) (0)
- Uracil excision repair pathway activities are not intrinsic to nucleoside diphosphate kinases from Mycobacterium tuberculosis and Escherichia coli. (2004) (0)
- Crystal structure of ribosome recycling factor mutant R109A from Mycobacterium tuberculosis (2014) (0)
- Crystal structure of Uracil-DNA Glycosylase from Mycobacterium tuberculosis in complex with a proteinaceous inhibitor (2008) (0)
- Avoiding acidic region streaking in two-dimensional gel electrophoresis: Case study with two bacterial whole cell protein extracts (2014) (0)
- Crystal structure of Uracil DNA glycosylase-Uracil complex from Bradyrhizobium diazoefficiens. (2017) (0)
- Correction to Paralogous cAMP Receptor Proteins in Mycobacterium smegmatis Show Biochemical and Functional Divergence (2015) (0)
- Surveillance of the nucleotide pool: insights into the catalytic mechanism of mycobacterial antimutator protein MutT2 (2018) (0)
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