Vincent C. Manganiello
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Biology
Vincent C. Manganiello's Degrees
- Masters Molecular Biology Stanford University
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(Suggest an Edit or Addition)Vincent C. Manganiello's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases (2012) (1189)
- Foxp3-dependent programme of regulatory T-cell differentiation (2007) (1146)
- Advances in targeting cyclic nucleotide phosphodiesterases (2014) (609)
- Structure, Localization, and Regulation of cGMP-inhibited Phosphodiesterase (PDE3)* (1997) (447)
- Tumor necrosis factor-alpha stimulates lipolysis in differentiated human adipocytes through activation of extracellular signal-related kinase and elevation of intracellular cAMP. (2002) (420)
- Cyclic nucleotide phosphodiesterase 3A-deficient mice as a model of female infertility. (2004) (242)
- Diversity in cyclic nucleotide phosphodiesterase isoenzyme families. (1995) (217)
- Functional incorporation of ganglioside into intact cells: induction of choleragen responsiveness. (1976) (211)
- Regulation and function of the cyclic nucleotide phosphodiesterase (PDE3) gene family. (2001) (210)
- An effect of insulin on cyclic adenosine 3':5'-monophosphate phosphodiesterase activity in fat cells. (1973) (208)
- Clinical and molecular genetics of the phosphodiesterases (PDEs). (2014) (184)
- Resveratrol as a calorie restriction mimetic: therapeutic implications. (2012) (173)
- Evidence that insulin and isoprenaline activate the cGMP-inhibited low-Km cAMP phosphodiesterase in rat fat cells by phosphorylation. (1990) (164)
- Alterations in regulation of energy homeostasis in cyclic nucleotide phosphodiesterase 3B-null mice. (2006) (160)
- Effects of lipolytic and antilipolytic agents on cyclic 3',5'-adenosine monophosphate in fat cells. (1971) (159)
- Distinctive anatomical patterns of gene expression for cGMP-inhibited cyclic nucleotide phosphodiesterases. (1995) (158)
- Molecular cloning and expression of human myocardial cGMP-inhibited cAMP phosphodiesterase. (1992) (150)
- Effects of atrial natriuretic factor on cyclic guanosine monophosphate and cyclic adenosine monophosphate accumulation in microdissected nephron segments from rats. (1987) (150)
- Presence of autoantibody for phospholipase inhibitory protein, lipomodulin, in patients with rheumatic diseases. (1981) (149)
- A simple, sensitive protein-binding assay for guanosine 3':5'-monophosphate. (1971) (149)
- Protein phosphatase 2A is the main phosphatase involved in the regulation of protein kinase B in rat adipocytes. (2002) (146)
- Phorbol 12-myristate 13-acetate and vasopressin potentiate the effect of corticotropin-releasing factor on cyclic AMP production in rat anterior pituitary cells. Mechanisms of action. (1987) (146)
- Hydrolysis of nicotinamide adenine dinucleotide by choleragen and its A protomer: possible role in the activation of adenylate cyclase. (1976) (142)
- Regulation of AMP-activated protein kinase by cAMP in adipocytes: roles for phosphodiesterases, protein kinase B, protein kinase A, Epac and lipolysis. (2009) (138)
- Molecular cloning of the rat adipocyte hormone-sensitive cyclic GMP-inhibited cyclic nucleotide phosphodiesterase. (1993) (132)
- Isoforms of Cyclic Nucleotide Phosphodiesterase PDE3A in Cardiac Myocytes* (2002) (127)
- Essential role of phosphatidylinositol 3‐kinase in insulin‐induced activation and phosphorylation of the cGMP‐inhibited cAMP phosphodiesterase in rat adipocytes studies using the selective inhibitor wortmannin (1994) (125)
- Insulin-Induced Phosphorylation and Activation of Phosphodiesterase 3B in Rat Adipocytes: Possible Role for Protein Kinase B But Not Mitogen-Activated Protein Kinase or p70 S6 Kinase. (1998) (124)
- Type III cGMP-inhibited cyclic nucleotide phosphodiesterases (PDE3 gene family). (1995) (121)
- Evidence for the key role of the adipocyte cGMP-inhibited cAMP phosphodiesterase in the antilipolytic action of insulin. (1995) (117)
- Isoforms of Cyclic Nucleotide Phosphodiesterase PDE3 and Their Contribution to cAMP Hydrolytic Activity in Subcellular Fractions of Human Myocardium* (2005) (113)
- Cyclic nucleotide phosphodiesterases: important signaling modulators and therapeutic targets. (2015) (110)
- Cyclic Nucleotide Phosphodiesterases (PDEs): Diverse Regulators of Cyclic Nucleotide Signals and Inviting Molecular Targets for Novel Therapeutic Agents (1999) (109)
- Phosphodiesterase Type 3A Regulates Basal Myocardial Contractility Through Interacting With Sarcoplasmic Reticulum Calcium ATPase Type 2a Signaling Complexes in Mouse Heart (2013) (107)
- Agents that increase cyclic AMP inhibit accumulation of cGMP and depress human monocyte locomotion. (1978) (107)
- Purification of the putative hormone-sensitive cyclic AMP phosphodiesterase from rat adipose tissue using a derivative of cilostamide as a novel affinity ligand. (1987) (106)
- Hormone-sensitive cyclic GMP-inhibited cyclic AMP phosphodiesterase in rat adipocytes. Regulation of insulin- and cAMP-dependent activation by phosphorylation. (1991) (106)
- From PDE3B to the regulation of energy homeostasis. (2011) (104)
- An effect of dexamethasone on adenosine 3',5'-monophosphate content and adenosine 3',5'-monophosphate phosphodiesterase activity of cultured hepatoma cells. (1972) (101)
- Sarcoplasmic reticulum-associated cyclic adenosine 5'-monophosphate phosphodiesterase activity in normal and failing human hearts. (1991) (97)
- Down-regulation of cyclic-nucleotide phosphodiesterase 3B in 3T3-L1 adipocytes induced by tumour necrosis factor alpha and cAMP. (2000) (96)
- Role of phosphodiesterase type 3A and 3B in regulating platelet and cardiac function using subtype-selective knockout mice. (2007) (93)
- Steroid-sparing effects of pentoxifylline in pulmonary sarcoidosis. (2009) (93)
- Important Role of Phosphodiesterase 3B for the Stimulatory Action of cAMP on Pancreatic β-Cell Exocytosis and Release of Insulin* (2002) (91)
- Phosphorylation and activation of hormone-sensitive adipocyte phosphodiesterase type 3B. (1998) (85)
- Phosphodiesterase 4D Regulates Baseline Sarcoplasmic Reticulum Ca2+ Release and Cardiac Contractility, Independently of L-Type Ca2+ Current (2011) (84)
- Bradykinin stimulates phospholipid methylation, calcium influx, prostaglandin formation, and cAMP accumulation in human fibroblasts. (1983) (84)
- Modification of calmodulin function by enzymatic carboxyl methylation (1981) (82)
- Role of PDE3B in insulin-induced glucose uptake, GLUT-4 translocation and lipogenesis in primary rat adipocytes. (2006) (80)
- Phosphorylation of PDE3B by Phosphatidylinositol 3-Kinase Associated with the Insulin Receptor* (2000) (77)
- Assay of cyclic nucleotide phosphodiesterase using radiolabeled and fluorescent substrates. (1988) (74)
- Effects of bradykinin and indomethacin on cyclic GMP and cyclic AMP in lung slices. (1973) (73)
- Receptors for bradykinin in intact cultured human fibroblasts. Identification and characterization by direct binding study. (1983) (72)
- Characterization of two recombinant PDE3 (cGMP-inhibited cyclic nucleotide phosphodiesterase) isoforms, RcGIP1 and HcGIP2, expressed in NIH 3006 murine fibroblasts and Sf9 insect cells. (1996) (72)
- Characterization of the cDNA and gene encoding human PDE3B, the cGIP1 isoform of the human cyclic GMP-inhibited cyclic nucleotide phosphodiesterase family. (1996) (71)
- Re-discovering PDE3 inhibitors--new opportunities for a long neglected target. (2007) (70)
- Inactivation of NF-κB p65 (RelA) in Liver Improves Insulin Sensitivity and Inhibits cAMP/PKA Pathway (2015) (70)
- Functions of the N-terminal Region of Cyclic Nucleotide Phosphodiesterase 3 (PDE 3) Isoforms* (2000) (70)
- Antilipolytic action of insulin: role of cAMP phosphodiesterase activation. (1985) (68)
- Hormone-sensitive particulate cAMP phosphodiesterase activity in 3T3-L1 adipocytes. Regulation of responsiveness by dexamethasone. (1983) (66)
- The Role of PDE3B Phosphorylation in the Inhibition of Lipolysis by Insulin (2015) (66)
- Purification and characterization of cyclic GMP-stimulated cyclic nucleotide phosphodiesterase from calf liver. Effects of divalent cations on activity. (1983) (65)
- Effects of guanosine 3',5'-monophosphate on glycerol production and accumulation of adenosine 3',5'-monophosphate by fat cells. (1970) (65)
- Compartmentalized Cyclic Adenosine 3′,5′-Monophosphate at the Plasma Membrane Clusters PDE3A and Cystic Fibrosis Transmembrane Conductance Regulator into Microdomains (2010) (64)
- Targeted disruption of PDE3B, but not PDE3A, protects murine heart from ischemia/reperfusion injury (2011) (64)
- β-Cell-targeted Overexpression of Phosphodiesterase 3B in Mice Causes Impaired Insulin Secretion, Glucose Intolerance, and Deranged Islet Morphology* (2004) (64)
- The effect of serotonin (5-hydroxytryptamine) and derivatives on guanosine 3',5'-monophosphate in human monocytes. (1975) (63)
- Guanosine 3',5'-monophosphate and adenosine 3',5'-monophosphate content of human umbilical artery. (1975) (62)
- Phosphorylation and activation of phosphodiesterase type 3B (PDE3B) in adipocytes in response to serine/threonine phosphatase inhibitors: deactivation of PDE3B in vitro by protein phosphatase type 2A. (1999) (61)
- Phosphodiesterase 3A (PDE3A) Deletion Suppresses Proliferation of Cultured Murine Vascular Smooth Muscle Cells (VSMCs) via Inhibition of Mitogen-activated Protein Kinase (MAPK) Signaling and Alterations in Critical Cell Cycle Regulatory Proteins* (2011) (60)
- Regulation of hormone-sensitive lipase activity in adipose tissue. (1997) (59)
- The role of calcium in regulation of cyclic nucleotide content in human umbilical artery. (1975) (58)
- Identification of a novel isoform of the cyclic-nucleotide phosphodiesterase PDE3A expressed in vascular smooth-muscle myocytes. (2001) (58)
- Insulin-induced formation of macromolecular complexes involved in activation of cyclic nucleotide phosphodiesterase 3B (PDE3B) and its interaction with PKB. (2007) (58)
- Autoregulation of bradykinin receptors and bradykinin-induced prostacyclin formation in human fibroblasts. (1984) (57)
- Plasma membrane cyclic nucleotide phosphodiesterase 3B (PDE3B) is associated with caveolae in primary adipocytes. (2006) (57)
- Serum apolipoprotein A-I and large high-density lipoprotein particles are positively correlated with FEV1 in atopic asthma. (2015) (56)
- Differential expression of cyclic nucleotide phosphodiesterase 3 and 4 activities in human T cell clones specific for myelin basic protein. (1997) (56)
- Cyclic Nucleotide Phosphodiesterase 3B Is a Downstream Target of Protein Kinase B and May Be Involved in Regulation of Effects of Protein Kinase B on Thymidine Incorporation in FDCP2 Cells1 (2000) (53)
- Stimulation of monocyte cGMP by leukocyte dialysates. An antigen-independent property of dialyzable transfer factor. (1975) (52)
- Purification and properties of calmodulin-stimulated phosphodiesterase from mammalian brain. (1984) (52)
- Regulation of Sarcoplasmic Reticulum Ca2+ ATPase 2 (SERCA2) Activity by Phosphodiesterase 3A (PDE3A) in Human Myocardium (2015) (52)
- Selective effects of phosphodiesterase inhibitors on different phosphodiesterases, adenosine 3',5'-monophosphate metabolism, and lipolysis in 3T3-L1 adipocytes. (1984) (51)
- Synthesis and uptake of gangliosides by choleragen-responsive human fibroblasts. (1977) (51)
- Selective loss of adipose cell responsiveness to glucagon with growth in the rat. (1972) (51)
- Cytosolic and sarcoplasmic reticulum-associated low Km, cGMP-inhibited cAMP phosphodiesterase in mammalian myocardium. (1993) (50)
- Effect of adipocyte beta3-adrenergic receptor activation on the type 2 diabetic MKR mice. (2006) (50)
- Protein kinase B is expressed in pancreatic beta cells and activated upon stimulation with insulin-like growth factor I. (1998) (49)
- Effects of epinephrine, adrenocorticotrophic hormone, and theophylline on adenosine 3', 5'-monophosphate phosphodiesterase activity in fat cells. (1974) (49)
- Heme Oxygenase-1 Regulation of Matrix Metalloproteinase-1 Expression Underlies Distinct Disease Profiles in Tuberculosis (2015) (49)
- A role for soluble cAMP phosphodiesterases in differentiation of 3T3‐L1 adipocytes (1985) (49)
- The effect of polystyrene beads on cyclic 3',5'-adenosine monophosphate concentration in leukocytes. (1971) (48)
- Purification and properties of the cGMP-inhibited cAMP phosphodiesterase from bovine aortic smooth muscle. (1992) (48)
- The relationship between ribosomes and the endoplasmic reticulum during protein synthesis. (1965) (47)
- Identification of the Site in the cGMP-inhibited Phosphodiesterase Phosphorylated in Adipocytes in Response to Insulin and Isoproterenol (*) (1996) (46)
- Selective inhibition of cGMP-inhibited and cGMP-noninhibited cyclic nucleotide phosphodiesterases and relaxation of rat aorta. (1991) (44)
- Purines in cellular signaling : targets for new drugs (1990) (44)
- Expression and Regulation of Cyclic Nucleotide Phosphodiesterases in Human and Rat Pancreatic Islets (2010) (44)
- Differential regulation of adipocyte PDE3B in distinct membrane compartments by insulin and the beta3-adrenergic receptor agonist CL316243: effects of caveolin-1 knockdown on formation/maintenance of macromolecular signalling complexes. (2009) (44)
- Insulin induced phosphorylation and activation of the cGMP-inhibited cAMP phosphodiesterase in human platelets. (1992) (43)
- Identification of the phosphorylation site in vitro for cAMP-dependent protein kinase on the rat adipocyte cGMP-inhibited cAMP phosphodiesterase. (1994) (43)
- Cyclic adenosine 3',5'-monophosphate regulation of corticotropin-releasing hormone promoter activity in AtT-20 cells and in a transformed hypothalamic cell line. (2003) (43)
- Single-step affinity purification, partial structure and properties of human platelet cGMP inhibited cAMP phosphodiesterase. (1994) (42)
- Guanosine cyclic 3',5'-monophosphate and guanylate cyclase activity in guinea pig lung: effects of acetylcholine and cholinesterase inhibitors. (1974) (42)
- Substrate and effector specificity of a guanosine 3':5'-monophosphate phosphodiesterase from rat liver. (1977) (41)
- Oxygen and cyclic nucleotides in human umbilical artery. (1975) (40)
- IL-3 and IL-4 activate cyclic nucleotide phosphodiesterases 3 (PDE3) and 4 (PDE4) by different mechanisms in FDCP2 myeloid cells. (1999) (40)
- Characterization of particulate cyclic nucleotide phosphodiesterases from bovine brain: purification of a distinct cGMP-stimulated isoenzyme. (1990) (39)
- Enzymatic and chemical oxidation of gangliosides in cultured cells: effects of choleragen. (1977) (38)
- Complex effects of inhibitors on cyclic GMP-stimulated cyclic nucleotide phosphodiesterase. (1983) (38)
- Beta-cell PDE3B regulates Ca2+-stimulated exocytosis of insulin. (2007) (38)
- Cyclic Nucleotide Phosphodiesterase 3 Signaling Complexes (2012) (38)
- Effects of thyroid hormone on regulation of lipolysis and adenosine 3',5'-monophosphate metabolism in 3T3-L1 adipocytes. (1985) (38)
- Role of hormone-sensitive low Km cAMP phosphodiesterase in regulation of cAMP-dependent protein kinase and lipolysis in rat adipocytes. (1989) (38)
- Expression, Activity, and Function of Phosphodiesterases in the Mature and Immature Ductus Arteriosus (2008) (37)
- Effects of prostaglandin E1 and isoproterenol on cyclic AMP content of human fibroblasts modified by time and cell density in subculture. (1974) (35)
- A Novel Insulin Secretagogue Is a Phosphodiesterase Inhibitor (1995) (35)
- Protein kinase A-dependent activation of PDE4 (cAMP-specific cyclic nucleotide phosphodiesterase) in cultured bovine vascular smooth muscle cells. (1997) (34)
- C(2)-ceramide influences the expression and insulin-mediated regulation of cyclic nucleotide phosphodiesterase 3B and lipolysis in 3T3-L1 adipocytes. (2002) (34)
- Novel mechanisms of the regulation of protein kinase B in adipocytes; implications for protein kinase A, Epac, phosphodiesterases 3 and 4. (2007) (34)
- Purification of hepatic microsomal membranes. (1972) (34)
- Dual effects of pituitary adenylate cyclase-activating polypeptide and isoproterenol on lipid metabolism and signaling in primary rat adipocytes. (2003) (33)
- Role of PDE3A in regulation of cell cycle progression in mouse vascular smooth muscle cells and oocytes: implications in cardiovascular diseases and infertility. (2011) (33)
- Stimulation by insulin of a serine kinase in human platelets that phosphorylates and activates the cGMP-inhibited cAMP phosphodiesterase. (1993) (33)
- Selective inhibition of two soluble adenosine cyclic 3',5'-phosphate phosphodiesterases partially purified from calf liver. (1984) (33)
- Modulation of Polycystic Kidney Disease Severity by Phosphodiesterase 1 and 3 Subfamilies. (2016) (32)
- Phosphodiesterase 3B Is Localized in Caveolae and Smooth ER in Mouse Hepatocytes and Is Important in the Regulation of Glucose and Lipid Metabolism (2009) (32)
- cGMP-inhibited phosphodiesterases (PDE3 gene family). (1996) (32)
- Regulation of cyclic nucleotide phosphodiesterases in cultured hepatoma cells by dexamethasone and N6,O2'-dibutyryl adenosine 3':k'-monophosphate. (1977) (32)
- Selective regulation by pertussis toxin of insulin-induced activation of particulate cAMP phosphodiesterase activity in 3T3-L1 adipocytes. (1983) (32)
- Insulin-induced translocation of protein kinase B to the plasma membrane in rat adipocytes. (1998) (31)
- Multisite phosphorylation of adipocyte and hepatocyte phosphodiesterase 3B. (2007) (31)
- Calmodulin-activated cyclic nucleotide phosphodiesterase from brain. Relationship of subunit structure to activity assessed by radiation inactivation. (1981) (30)
- Effect of serum on ganglioside uptake and choleragen responsiveness of transformed mouse fibroblasts. (1978) (29)
- Early and rapid development of insulin resistance, islet dysfunction and glucose intolerance after high-fat feeding in mice overexpressing phosphodiesterase 3B. (2006) (29)
- Relaxant effects of the selective phosphodiesterase inhibitors milrinone and OPC 3911 on isolated human mesenteric vessels. (1989) (28)
- A pathophysiological role of PDE3 in allergic airway inflammation. (2018) (28)
- Interaction of phosphodiesterase 3A with brefeldin A-inhibited guanine nucleotide-exchange proteins BIG1 and BIG2 and effect on ARF1 activity (2009) (28)
- Calmodulin-activated cyclic nucleotide phosphodiesterase from brain. Changes in molecular size assessed by gel filtration and electrophoresis. (1981) (28)
- Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue (2016) (27)
- Type III cyclic nucleotide phosphodiesterases and insulin action. (1996) (27)
- Selective regulation of cyclic nucleotide phosphodiesterase PDE3A isoforms (2013) (26)
- Characterization of phosphodiesterase 3 in human malignant melanoma cell line. (2002) (26)
- Mechanisms for activation of the rat adipocyte particulate cyclic-GMP-inhibited cyclic AMP phosphodiesterase and its importance in the antilipolytic action of insulin. (1992) (26)
- White to beige conversion in PDE3B KO adipose tissue through activation of AMPK signaling and mitochondrial function (2017) (25)
- Cyclic nucleotide phosphodiesterases (PDE) 3 and 4 in normal, malignant, and HTLV-I transformed human lymphocytes. (1999) (24)
- Activation and inhibition of fat cell adenylate cyclase by fluoride. (1976) (24)
- Identification of the site in the cGMP-inhibited phosphodiesterase phosphorylated in adipocytes in response to insulin and isoproterenol. (2009) (24)
- Insulin-induced phosphorylation and activation of phosphodiesterase 3B in rat adipocytes: possible role for protein kinase B but not mitogen-activated protein kinase or p70 S6 kinase. (1998) (23)
- A role for phosphodiesterase 3B in acquisition of brown fat characteristics by white adipose tissue in male mice. (2013) (23)
- Mechanisms of inhibition of lipolysis by insulin, vanadate and peroxovanadate in rat adipocytes (1999) (22)
- Effects of the human immunodeficiency virus-protease inhibitor, ritonavir, on basal and catecholamine-stimulated lipolysis. (2005) (22)
- Molecular mechanisms involved in the antilipolytic action of insulin: phosphorylation and activation of a particulate adipocyte cAMP phosphodiesterase. (1991) (22)
- Role of phosphodiesterase 2 in growth and invasion of human malignant melanoma cells. (2014) (21)
- Subcellular localization and biological function of specific cyclic nucleotide phosphodiesterases. (1987) (20)
- Cyclic nucleotide phosphodiesterase 5 and sildenafil: promises realized. (2003) (20)
- Effect of dexamethasone on adenosine 3',5'-monophosphate content and phosphodiesterase activities in 3T3-L1 adipocytes. (1984) (19)
- Regulation of activity of purified guanylate cyclase from liver that is unresponsive to nitric oxide. (1983) (19)
- Effects of chymotrypsin and a calcium-dependent protein activator on guanosine 3',5'-monophosphate phosphodiesterase from rat liver. (1978) (19)
- 6 – cGMP-Inhibited Phosphodiesterases (PDE3) (1996) (19)
- Regulation of the pro-inflammatory cytokine osteopontin by GIP in adipocytes--a role for the transcription factor NFAT and phosphodiesterase 3B. (2012) (19)
- Cyclic Nucleotide Phosphodiesterase 3B Is a Downstream Target of Protein Kinase B and May Be Involved in Regulation of Effects of Protein Kinase B on Thymidine Incorporation in FDCP2 Cells (2000) (18)
- Phosphodiesterase 3A: a new player in development of interstitial cells of Cajal and a prospective target in gastrointestinal stromal tumors (GIST) (2017) (18)
- Cardiac type cGMP-inhibited phosphodiesterase (PDE3A) gene structure: similarity and difference to adipocyte type PDE3B gene. (2000) (18)
- Texture-based computer-aided diagnosis system for lung fibrosis (2007) (18)
- Roles of ATP in insulin actions. (1994) (17)
- Purines in Cellular Signaling (1990) (16)
- Regulation of cyclic nucleotide phosphodiesterase activity. (1981) (16)
- Evidence for the presence of several phosphodiesterase isoforms in brown adipose tissue of Zucker rats: modulation of PDE2 by the fa gene expression (1999) (16)
- Selective inhibitors of specific phosphodiesterases in intact adipocytes. (1988) (16)
- Purification and characterization of phosphodiesterase activator from kidney. A lysosomal protease. (1979) (16)
- Calcium uptake by subcellular fractions of human umbilical artery. (1976) (15)
- Long-term regulation of cyclic nucleotide phosphodiesterase type 3B and 4 in 3T3-L1 adipocytes. (2007) (15)
- Female infertility in PDE3A-/- mice (2010) (15)
- Expression and characterization of deletion recombinants of two cGMP-inhibited cyclic nucleotide phosphodiesterases (PDE-3) (2007) (15)
- Phosphodiesterase 4 in osteoblastic osteosarcoma cells as a potential target for growth inhibition (2003) (14)
- Expression and role of phosphodiesterase 3 in human squamous cell carcinoma KB cells (2002) (14)
- Milrinone efficiently potentiates insulin secretion induced by orally but not intravenously administered glucose in C57BL6J mice. (2004) (14)
- Importance of cAMP-response Element-binding Protein in Regulation of Expression of the Murine Cyclic Nucleotide Phosphodiesterase 3B (Pde3b) Gene in Differentiating 3T3-L1 Preadipocytes* (2006) (13)
- Solubilization and characterization of hormone- responsive phosphodiesterase activity of rat fat cells. (1977) (13)
- Expression and Activity of LowKm, cGMP-Inhibited cAMP Phosphodiesterase in Cardiac and Skeletal Muscle (1996) (13)
- Effects of choleragen on hormonal responsiveness of adenylate cyclase in human fibroblasts and rat fat cells. (1976) (13)
- Reversible inactivation of soluble liver guanylate cyclase by disulfides. (1981) (13)
- Purification and characterization of guanosine 3',5'-monophosphate-inhibited low K(m) adenosine 3',5'-monophosphate phosphodiesterase from human placental cytosolic fractions. (1992) (13)
- Mechanisms of inhibition of lipolysis by insulin, vanadate and peroxovanadate in rat adipocytes. (1999) (13)
- Comparison of putative cGMP-binding regions in bovine brain and cardiac cGMP-stimulated phosphodiesterases. (1991) (13)
- Mechanism of enhanced sensitivity to bradykinin in pertussis toxin-treated fibroblasts: toxin increases bradykinin-stimulated prostaglandin formation. (1988) (13)
- Effects of nitroprusside and nitroglycerin on cGMP content and PGI2 formation in aorta and vena cava. (1989) (13)
- Hormonal regulation of adipocyte particulate "low Km" cAMP phosphodiesterase. (1986) (12)
- Effect of thyroxine on the disaturated lecithin content of lung. (2015) (12)
- Phosphodiesterase activator from rat kidney cortex. (1978) (12)
- Effect of N6-(L-2-phenylisopropyl)adenosine and insulin on cAMP metabolism in 3T3-L1 adipocytes. (1987) (12)
- Phosphodiesterase 3B: An Important Regulator of Energy Homeostasis (2006) (12)
- Effect of bradykinin on prostaglandin production by human skin fibroblasts in culture. (1985) (11)
- Phosphodiesterase type 3A (PDE3A), but not type 3B (PDE3B), contributes to the adverse cardiac remodeling induced by pressure overload. (2019) (11)
- Analysis of the kinetics of cyclic AMP hydrolysis by the cyclic GMP-stimulated cyclic nucleotide phosphodiesterase. (1987) (10)
- Expression and activity of low Km, cGMP-inhibited cAMP phosphodiesterase in cardiac and skeletal muscle. (1996) (10)
- Down-regulation of cyclic-nucleotide phosphodiesterase 3 B in 3 T 3L 1 adipocytes induced by tumour necrosis factor α and cAMP (10)
- Effects of pH on allosteric and catalytic properties of the guanosine cyclic 3',5'-phosphate stimulated cyclic nucleotide phosphodiesterase from calf liver. (1987) (10)
- Ser-474 is the major target of insulin-mediated phosphorylation of protein kinase B beta in primary rat adipocytes. (2002) (9)
- Purification, properties and polyclonal antibodies for the particulate, low Km cAMP phosphodiesterase from bovine adipose tissue. (1988) (9)
- Effects of fatty acids on activity of cGMP-stimulated cyclic nucleotide phosphodiesterase from calf liver. (1984) (9)
- Effects of temperature on allosteric and catalytic properties of the cGMP-stimulated cyclic nucleotide phosphodiesterase from calf liver. (1987) (9)
- Regulation of specific forms of cyclic nucleotide phosphodiesterases in cultured cells. (1984) (8)
- Effects of spermine on activity and stability of calcium-dependent guanosine 3',5'-monophosphate phosphodiesterase. (1979) (8)
- Effects of d- and l-propranolol on the responsiveness of human fibroblasts to choleragen and prostaglandin E1. (1981) (7)
- Insulin and isoproterenol induce phosphorylation of the particulate cyclic GMP-inhibited, low Km cyclic AMP phosphodiesterase (cGI PDE) in 3T3-L1 adipocytes. (1992) (6)
- Short‐term regulation of PDE4 activity (2002) (6)
- Methods to study phosphorylation and activation of the hormone-sensitive adipocyte phosphodiesterase type 3B in rat adipocytes. (2001) (6)
- Purification and Characterization of Cyclic GMP-stimulated Cyclic Nucleotide Phosphodiesterase from Calf Liver (2001) (6)
- Products of reaction catalyzed by purified rat liver guanylate cyclase determined by 31p NMR spectroscopy. (1980) (6)
- SFPQ, a multifunctional nuclear protein, regulates the transcription of PDE3A (2017) (6)
- Purification of guanylate cyclase from rat liver supernatant. (1978) (6)
- Identification of promoter elements in 5'-flanking region of murine cyclic nucleotide phosphodiesterase 3B gene. (2005) (5)
- PROTEIN CARBOXYL‐METHYLASE MODIFIES CALMODULIN FUNCTION * (1980) (5)
- Phosphodiesterase 3 and 4 Inhibition: Facing a Bright Future in Asthma Control (2018) (5)
- Systematic search for single nucleotide polymorphisms in the 5' flanking region of the human phosphodiesterase 3B gene: absence of evidence for major effects of identified polymorphisms on susceptibility to Japanese type 2 diabetes. (2003) (5)
- Ca2+-independent cyclic GMP phosphodiesterases from rat liver and HTC hepatoma cells. (1983) (4)
- Cyclic nucleotide PDE-3. Quantitation of PDE-3A and -3B mRNAs in rat tissues by RNase protection assay. (1998) (4)
- Regulation by bradykinin of its receptor and of receptor-mediated prostacyclin formation in cultured human fibroblasts. (1983) (4)
- A pathophysiological role of PDE 3 in allergic airway inflammation (2018) (3)
- Expression of cyclic nucleotide phosphodiesterase 3A in isolated rat submandibular acini. (2006) (3)
- Tuberous sclerosis complex 2 loss of heterozygosity in patients with lung disease and cancer. (2015) (3)
- CHAPTER 194 – cAMP/cGMP Dual-Specificity Phosphodiesterases (2003) (3)
- Phosphodiesterase 3 B is localized in caveolae and smooth ER in mouse hepatocytes and is important in the regulation of glucose and lipid metabolism (2009) (3)
- Alterations in cyclic AMP phosphodiesterase activities during differentiation of 3T3-L1 cells. (1983) (3)
- CYCLIC NUCLEOTIDE PHOSPHODIESTERASES (2004) (3)
- Effects of nitroprusside on the bradykinin responsiveness of human fibroblasts. (1986) (3)
- Expression of phosphodiesterase 3 in rat submandibular gland cell lines. (2001) (3)
- cAMP/cGMP Dual-Specificity Phosphodiesterases (2010) (3)
- Cyclic nucleotide phosphodiesterases: critical modulators of endocrine, metabolic, and cardiovascular function and appealing therapeutic targets. (2011) (2)
- Purification of a cGMP-inhibited cAMP Phosphodiesterase from Vascular Smooth Muscle (1990) (2)
- Phosphodiesterase 4D Regulates Baseline Sarcoplasmic Reticulum Ca 2 Release and Cardiac Contractility, Independently of L-Type Ca 2 Current Short Communication (2011) (2)
- Bradykinin receptor stimulation of cAMP involves phospholipid methylation, Ca flux, phospholipase A2 activation and prostaglandin formation (1981) (2)
- Adenovirus-mediated overexpression of murine cyclic nucleotide phosphodiesterase 3B. (2005) (2)
- Cyclic nucleotide PDE-3 (2007) (2)
- Regulation of cyclic nucleotide phosphodiesterase 3 (PDE3) (2007) (2)
- Activation of kidney guanylate cyclase by cobalt. (1978) (2)
- Emergence and success of PDE5 inhibitors as effective therapy for erectile dysfunction. (2004) (1)
- Effects of heterologous expression of human cyclic nucleotide phosphodiesterase 3A (hPDE3A) on redox regulation in yeast. (2016) (1)
- Insulin‐induced formation of macromolecular complexes involved in activation of Phosphodiesterase3B (PDE3B) in 3T3‐L1 adipocytes (2007) (1)
- Effect of the phosphodiesterase 4 inhibitor, rolipram, on retinoic acid-increased alkaline phosphatase activity in the mouse fibroblastic C3H10T1/2 cell line. (2003) (1)
- Targeting PDE3 Abrogates the Hallmarks of Asthma in Asthma Models (2018) (1)
- Phosphorylation‐dependent Association of PDE3A1 with SERCA2 and its Regulation of SERCA2 Activity in Human Myocardium (2015) (1)
- Oxygen: influence on cyclic nucleotides and calcium sequestration in the human umbilical artery. (1977) (1)
- Mechanism for Dual Regulation of the Particulate cGMP-Inhibited cAMP Phosphodiesterase in Rat Adipocytes by Isoproterenol and Insulin (1990) (0)
- PDE3A Deletion Suppresses Mouse VSMC Proliferation via Inhibition of MAPK Signaling and Cell Cycle Arrest (2011) (0)
- Stimulation of Monocyte cGMP by Leukocyte Dialysates (2013) (0)
- PKA‐induced Interaction of Phosphorylated PDE3A (pPDE3A) and BIG1 (Brefeldin A‐inhibited guanine nucleotide exchange protein 1) in Cytosolic Fractions from Human Myocardium may be Important in Regulation of BIG1 Function (2012) (0)
- Effects of Atrial Natriuretic Factor (ANF) on cGMP and cAMP Accumulation in Isolated Inner Medullary Collecting Ducts (IMCD) and Glomeruli (Glm) from Rats (1986) (0)
- Differential regulation of adipocyte PDE3B in distinct membrane compartments in response to insulin and CL316243 (2008) (0)
- Some effects of resveratrol and SRT1720 on PKA‐signaling and AMP‐kinase in adipocytes may be related to inhibition of Cyclic Nucleotide Phosphodiesterases (PDEs) (2011) (0)
- Phosphodiesterase 4D Regulates Baseline Sarcoplasmic Reticulum Ca 2 (cid:1) Release and Cardiac Contractility, Independently of L-Type Ca 2 (cid:1) Current Short Communication (2011) (0)
- Erratum: (Journal of Clinical Investigation (April 1995) 95:4 (1528- 1538)) (1997) (0)
- P-74: Mitogen-activated protein kinase and p70 ribosomal S6 kinase are not involved in the insulin-mediated phosphorylation of cGMP-inhibited phosphodiesterase (2009) (0)
- Phenotypic Characteristics of “ Fat-burning ” Brown Adipose Tissue ( BAT ) , with Reduced Expression of Pro-inflammatory Markers including the NLRP 3 Inflammasome (2014) (0)
- Distinct Disease Profiles in Tuberculosis Metalloproteinase-1 Expression Underlies Heme Oxygenase-1 Regulation of Matrix (2015) (0)
- In PDE3B KO mice, White Adipose Tissue (WAT) Exhibits Characteristics of “Good Fat,” i.e., Brown Adipose Tissue (BAT): II. Alterations in Angiogenesis and cAMP‐and AMP Kinase‐signaling (2009) (0)
- Potential Roles of Phosphodiesterase 3B Knockout in Acquisition of Brown Fat Characteristics by White Adipose Tissue in Mice (2012) (0)
- Stimulation ofMonocyte cGMP byLeukocyte Dialysates AN ANTIGEN-INDEPENDENT PROPERTY OF (1975) (0)
- Editorial Commentary (2004) (0)
- Phosphorylation regulates association of PDE3A isoforms with distinct interactomes (1013.23) (2014) (0)
- Dysregulation of Cdc25B in PDE3 mice oocytes (2007) (0)
- Cyclic nucleotide phosphodiesterase 3 B is connected to osteopontin and protein kinase CK 2 in pancreatic β-cells * (2013) (0)
- The Roles of Serine/Threonine Protein Phosphatases in Regulation of PDE3B Signaling in 3T3‐L1 Adipocytes (2009) (0)
- Cyclic Nucleotide Phosphodiesterase 3 Signaling Complexes (2012) (0)
- Heterologous expression of human phosphodiesterase 3A enhances oxidative stress resistance in yeast (2013) (0)
- Potential Role of PDE3B in Acquisition of Brown Fat Characteristic by White Adipose Tissue in Mice (2011) (0)
- Phosphodiesterase 3B (PDE3B) Regulates NLRP3 Inflammasome and Metabolic Cross Talk in Adipose Tissue (2016) (0)
- Expression of Cyclic GMP‐inhibited Phosphodiesterases 3A and 3B (PDE3A and PDE3B) in Human and Mice Cardiac Myocytes (2011) (0)
- Regulation of Sarcoplasmic Reticulum Ca 2 (cid:2) ATPase 2 (SERCA2) Activity by Phosphodiesterase 3A (PDE3A) in Human Myocardium INTERACTION OF PDE3A1 WITH SERCA2 * (2015) (0)
- PDE3A may regulate myocardial Ca2+ cycling through interacting with SERCA2 in mouse heart (2009) (0)
- Different Mechanisms in FDCP 2 Myeloid byPhosphodiesterases 3 ( PDE 3 ) and 4 ( PDE 4 ) IL-3 and IL-4 Activate Cyclic Nucleotide (1999) (0)
- Heterologous expression of human phosphodiesterase 3A (hPDE3A) improves ethanol production in Saccharomyces cerevisiae (2012) (0)
- Cyclic nucleotide phosphodiesterase 3B is connected to osteopontin and protein kinase CK2 in pancreatic β-cells * (2013) (0)
- Selection of cDNAs for phosphodiesterases that hydrolyze guanosine 3';5'-monophosphate in Escherichia coli. (1992) (0)
- Stimulation of Monocyte cGMP (0)
- Characterization of the insulin-sensitive low Km cAMP phosphodiesterase from rat adipose tissue (1986) (0)
- Heterologous expression of human phosphodiesterase 3A affects calcineurin‐mediated calcium homeostasis in yeast (2012) (0)
- Subcellular Localization of Human Myocardial PDE3 Isoforms and Components of cAMP Signaling Pathways (2009) (0)
- Effects of SRT1720 (SRT) and Resveratrol (RSV) on AMP‐activated protein kinase (AMPK) and PKA‐signaling in Adipocytes: Roles for Phosphodiesterase (PDE) (3 and 4) (2013) (0)
- Resveratrol and SRT-Mediated Activation of PKA- and AMP-Kinase Signaling in Adipocytes may be Related to Inhibition of Cyclic Nucleotide Phosphodiesterases (PDEs) (2012) (0)
- Activation of cGMP phosphodiesterase from bovine rod outer segments by limited proteolysis and ADP-ribosylation (1984) (0)
- Selective regulation of PDE3A isoforms by differential phosphorylation (2013) (0)
- Molecular and genomic analyses of human cGMP-inhibited cAMP phosphodiesterase (1994) (0)
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