Valeria Culotta
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American molecular biologist
Valeria Culotta's AcademicInfluence.com Rankings
Valeria Culottabiology Degrees
Biology
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#15236
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Molecular Biology
#2161
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#2195
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Biochemistry
#2425
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#2577
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Biology
Valeria Culotta's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Chemistry University of California, Berkeley
Why Is Valeria Culotta Influential?
(Suggest an Edit or Addition)According to Wikipedia, Valeria Cizewski Culotta is an American molecular biologist. Early life and education Culotta was born and raised in Maryland, where she graduated from Havre De Grace High School in 1975. She then completed her PhD in 1987 at Johns Hopkins University and her postdoctoral training in molecular biology at the National Cancer Institute.
Valeria Culotta's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Undetectable intracellular free copper: the requirement of a copper chaperone for superoxide dismutase. (1999) (1487)
- Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration (2002) (1059)
- The Copper Chaperone for Superoxide Dismutase* (1997) (781)
- Metallochaperones, an Intracellular Shuttle Service for Metal Ions* (2000) (728)
- A fraction of yeast Cu,Zn-superoxide dismutase and its metallochaperone, CCS, localize to the intermembrane space of mitochondria. A physiological role for SOD1 in guarding against mitochondrial oxidative damage. (2001) (655)
- Metal ion chaperone function of the soluble Cu(I) receptor Atx1. (1997) (620)
- Activation of superoxide dismutases: putting the metal to the pedal. (2006) (472)
- Histological Evidence of Protein Aggregation in Mutant SOD1 Transgenic Mice and in Amyotrophic Lateral Sclerosis Neural Tissues (2001) (432)
- A Role for the Saccharomyces cerevisiae ATX1 Gene in Copper Trafficking and Iron Transport* (1997) (412)
- Identification and Functional Expression of HAH1, a Novel Human Gene Involved in Copper Homeostasis* (1997) (369)
- Copper chaperone for superoxide dismutase is essential to activate mammalian Cu/Zn superoxide dismutase. (2000) (307)
- The ATX1 gene of Saccharomyces cerevisiae encodes a small metal homeostasis factor that protects cells against reactive oxygen toxicity. (1995) (267)
- Superoxide dismutase protects calcineurin from inactivation (1996) (264)
- Mutations in PMR1 suppress oxidative damage in yeast cells lacking superoxide dismutase (1995) (242)
- Battles with Iron: Manganese in Oxidative Stress Protection* (2012) (230)
- Factors Controlling the Uptake of Yeast Copper/Zinc Superoxide Dismutase into Mitochondria* (2003) (221)
- Saccharomyces cerevisiae Expresses Three Functionally Distinct Homologues of the Nramp Family of Metal Transporters (2000) (214)
- Identification of a functional homolog of the yeast copper homeostasis gene ATX1 from Arabidopsis. (1998) (210)
- The Yeast Copper/Zinc Superoxide Dismutase and the Pentose Phosphate Pathway Play Overlapping Roles in Oxidative Stress Protection* (1996) (208)
- SOD1 Integrates Signals from Oxygen and Glucose to Repress Respiration (2013) (197)
- Mechanisms for activating Cu- and Zn-containing superoxide dismutase in the absence of the CCS Cu chaperone. (2004) (194)
- Saccharomyces cerevisiae ISU1 and ISU2: members of a well-conserved gene family for iron-sulfur cluster assembly. (1999) (193)
- Fine mapping of a mouse metallothionein gene metal response element (1989) (191)
- Negative Control of Heavy Metal Uptake by the Saccharomyces cerevisiae BSD2 Gene* (1997) (186)
- Discovery of genes essential for heme biosynthesis through large-scale gene expression analysis. (2009) (183)
- Variation in the biochemical/biophysical properties of mutant superoxide dismutase 1 enzymes and the rate of disease progression in familial amyotrophic lateral sclerosis kindreds. (1999) (183)
- Suppressors of Superoxide Dismutase (SOD1) Deficiency in Saccharomyces cerevisiae (1998) (181)
- Multiple Protein Domains Contribute to the Action of the Copper Chaperone for Superoxide Dismutase* (1999) (178)
- Role of Saccharomyces cerevisiae ISA1and ISA2 in Iron Homeostasis (2000) (178)
- Crystal structure of the copper chaperone for superoxide dismutase (1999) (178)
- CRS5 encodes a metallothionein-like protein in Saccharomyces cerevisiae. (1994) (163)
- Chaperone-facilitated copper binding is a property common to several classes of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants. (1998) (163)
- A novel NADH kinase is the mitochondrial source of NADPH in Saccharomyces cerevisiae (2003) (161)
- Manganese Transport and Trafficking: Lessons Learned from Saccharomyces cerevisiae (2005) (160)
- The effects of mitochondrial iron homeostasis on cofactor specificity of superoxide dismutase 2 (2006) (145)
- Post-translation Control of Nramp Metal Transport in Yeast (1999) (143)
- The Saccharomyces cerevisiae High Affinity Phosphate Transporter Encoded by PHO84 Also Functions in Manganese Homeostasis* (2003) (143)
- Yeast lacking superoxide dismutase. Isolation of genetic suppressors. (1992) (142)
- The Yin and Yang of copper during infection (2016) (141)
- Structure-Function Analyses of the ATX1 Metallochaperone* (1999) (137)
- Manganese activation of superoxide dismutase 2 in Saccharomyces cerevisiae requires MTM1, a member of the mitochondrial carrier family (2003) (135)
- Manganese Superoxide Dismutase in Saccharomyces cerevisiae Acquires Its Metal Co-factor through a Pathway Involving the Nramp Metal Transporter, Smf2p* (2001) (124)
- Alternative Start Sites in the Saccharomyces cerevisiae GLR1 Gene Are Responsible for Mitochondrial and Cytosolic Isoforms of Glutathione Reductase* (2004) (123)
- Copper Activation of Superoxide Dismutase 1 (SOD1) in Vivo (2000) (122)
- The Copper Chaperone CCS Is Abundant in Neurons and Astrocytes in Human and Rodent Brain (1999) (119)
- Copper Chaperones: Personal Escorts for Metal Ions (2002) (117)
- The many highways for intracellular trafficking of metals (2003) (116)
- Manganese complexes: diverse metabolic routes to oxidative stress resistance in prokaryotes and yeast. (2013) (115)
- Manganese Activation of Superoxide Dismutase 2 in the Mitochondria of Saccharomyces cerevisiae* (2005) (111)
- Metal transporters that contribute copper to metallochaperones in Saccharomyces cerevisiae (2001) (110)
- Enhanced Effectiveness of Copper Ion Buffering by CUP1 Metallothionein Compared with CRS5 Metallothionein in Saccharomyces cerevisiae* (1996) (110)
- Activation of CuZn Superoxide Dismutases from Caenorhabditis elegans Does Not Require the Copper Chaperone CCS* (2005) (107)
- Uptake of lead and iron by divalent metal transporter 1 in yeast and mammalian cells. (2002) (107)
- Probing in vivo Mn2+ speciation and oxidative stress resistance in yeast cells with electron-nuclear double resonance spectroscopy (2010) (106)
- The overlapping roles of manganese and Cu/Zn SOD in oxidative stress protection. (2009) (106)
- Manganese homeostasis in Saccharomyces cerevisiae. (2009) (105)
- The Right to Choose: Multiple Pathways for Activating Copper,Zinc Superoxide Dismutase* (2009) (104)
- The role of the Saccharomyces cerevisiae CCC1 gene in the homeostasis of manganese ions (1996) (100)
- Candida albicans SOD5 represents the prototype of an unprecedented class of Cu-only superoxide dismutases required for pathogen defense (2014) (97)
- Candida albicans adapts to host copper during infection by swapping metal cofactors for superoxide dismutase (2015) (91)
- SOD Enzymes and Microbial Pathogens: Surviving the Oxidative Storm of Infection (2016) (90)
- Superoxide dismutase, oxidative stress, and cell metabolism. (2000) (86)
- Suppression of oxidative damage by Saccharomyces cerevisiae ATX2, which encodes a manganese-trafficking protein that localizes to Golgi-like vesicles (1996) (83)
- Regulation of metallothionein gene transcription by metals. (1990) (79)
- Supplying Copper to the Cuproenzyme Peptidylglycine α-Amidating Monooxygenase* (2003) (76)
- A Gain of Superoxide Dismutase (SOD) Activity Obtained with CCS, the Copper Metallochaperone for SOD1* (1999) (76)
- Role of Calprotectin in Withholding Zinc and Copper from Candida albicans (2017) (75)
- The requirement for yeast superoxide dismutase is bypassed through mutations in BSD2, a novel metal homeostasis gene (1994) (75)
- Intracellular pathways of copper trafficking in yeast and humans. (1999) (75)
- Cellular factors required for protection from hyperoxia toxicity in Saccharomyces cerevisiae. (2005) (74)
- Activation of Cu,Zn-Superoxide Dismutase in the Absence of Oxygen and the Copper Chaperone CCS* (2009) (71)
- A Manganese-rich Environment Supports Superoxide Dismutase Activity in a Lyme Disease Pathogen, Borrelia burgdorferi* (2013) (71)
- Regulation of Saccharomyces cerevisiae FET4 by oxygen and iron. (2002) (70)
- The distinct methods by which manganese and iron regulate the Nramp transporters in yeast. (2002) (65)
- The Interaction of Mitochondrial Iron with Manganese Superoxide Dismutase* (2009) (64)
- Oxidative Stress and Iron Are Implicated in Fragmenting Vacuoles of Saccharomyces cerevisiae Lacking Cu,Zn-Superoxide Dismutase* (1999) (64)
- Biological effects of CCS in the absence of SOD1 enzyme activation: implications for disease in a mouse model for ALS. (2008) (64)
- Mutational analysis of Saccharomyces cerevisiae Smf1p, a member of the Nramp family of metal transporters. (1999) (62)
- Factors and nucleotide sequences that direct ribosomal DNA transcription and their relationship to the stable transcription complex (1986) (57)
- Disrupted zinc-binding sites in structures of pathogenic SOD1 variants D124V and H80R. (2010) (55)
- The Effects of Glutaredoxin and Copper Activation Pathways on the Disulfide and Stability of Cu,Zn Superoxide Dismutase* (2006) (55)
- Transcription factor MBF-I interacts with metal regulatory elements of higher eucaryotic metallothionein genes (1989) (55)
- Copper and the ACE1 regulatory protein reversibly induce yeast metallothionein gene transcription in a mouse extract. (1989) (53)
- Sites of topoisomerase I action on X. laevis ribosomal chromatin: Transcriptionally active rDNA has an ∼200 bp repeating structure (1988) (53)
- Increased affinity for copper mediated by cysteine 111 in forms of mutant superoxide dismutase 1 linked to amyotrophic lateral sclerosis. (2007) (52)
- Mitochondrial Ccs1 contains a structural disulfide bond crucial for the import of this unconventional substrate by the disulfide relay system (2011) (52)
- The effect of phosphate accumulation on metal ion homeostasis in Saccharomyces cerevisiae (2010) (51)
- Instability of Superoxide Dismutase 1 of Drosophila in Mutants Deficient for Its Cognate Copper Chaperone*S⃞ (2008) (51)
- Eukaryotic copper-only superoxide dismutases (SODs): A new class of SOD enzymes and SOD-like protein domains (2017) (48)
- Down-regulation of a manganese transporter in the face of metal toxicity. (2009) (46)
- Manganese toxicity and Saccharomyces cerevisiae Mam3p, a member of the ACDP (ancient conserved domain protein) family. (2005) (44)
- Candida albicans FRE8 encodes a member of the NADPH oxidase family that produces a burst of ROS during fungal morphogenesis (2017) (44)
- Structural and biophysical properties of the pathogenic SOD1 variant H46R/H48Q. (2009) (41)
- Cell biology of copper (2009) (39)
- Species-specific activation of Cu/Zn SOD by its CCS copper chaperone in the pathogenic yeast Candida albicans (2014) (37)
- Analysis of Hypoxia and Hypoxia-Like States through Metabolite Profiling (2011) (35)
- Mutations in Saccharomyces cerevisiae Iron-Sulfur Cluster Assembly Genes and Oxidative Stress Relevant to Cu,Zn Superoxide Dismutase* (2004) (35)
- Intersection of phosphate transport, oxidative stress and TOR signalling in Candida albicans virulence (2018) (32)
- An Adaptation to Low Copper in Candida albicans Involving SOD Enzymes and the Alternative Oxidase (2016) (31)
- Supplying copper to the cuproenzyme peptidylglycine alpha-amidating monooxygenase. (2003) (29)
- Post-translational modification of Cu/Zn superoxide dismutase under anaerobic conditions. (2012) (28)
- Regulation of Manganese Antioxidants by Nutrient Sensing Pathways in Saccharomyces cerevisiae (2011) (27)
- The Phylogeny and Active Site Design of Eukaryotic Copper-only Superoxide Dismutases* (2016) (26)
- Chemical Warfare at the Microorganismal Level: A Closer Look at the Superoxide Dismutase Enzymes of Pathogens. (2018) (25)
- Superoxide dismutase null mutants of baker's yeast, Saccharomyces cerevisiae. (2002) (24)
- Eucaryotic transcription complexes are specifically associated in large sedimentable structures: rapid isolation of polymerase I, II, and III transcription factors (1985) (24)
- Mouse and frog violate the paradigm of species-specific transcription of ribosomal RNA genes. (1987) (23)
- Copper ions and the regulation ofSaccharomyces cerevisiae metallothionein genes under aerobic and anaerobic conditions (1996) (21)
- Cloned yeast and mammalian transcription factor TFIID gene products support basal but not activated metallothionein gene transcription. (1990) (18)
- Manganese transport in microorganisms. (2000) (16)
- Superoxide Triggers an Acid Burst in Saccharomyces cerevisiae to Condition the Environment of Glucose-starved Cells* (2012) (16)
- Changes in mammalian copper homeostasis during microbial infection. (2020) (16)
- Copper-only superoxide dismutase enzymes and iron starvation stress in Candida fungal pathogens (2019) (15)
- phnE and glpT Genes Enhance Utilization of Organophosphates in Escherichia coliK-12 (1998) (14)
- Exploiting the vulnerable active site of a copper-only superoxide dismutase to disrupt fungal pathogenesis (2018) (12)
- Regulation of Saccharomyces cerevisiae catalase gene expression by copper (1993) (12)
- Antimicrobial action of calprotectin that does not involve metal withholding. (2018) (11)
- Copper in infectious disease: Using both sides of the penny. (2021) (10)
- Phosphate disruption and metal toxicity in Saccharomyces cerevisiae: effects of RAD23 and the histone chaperone HPC2. (2012) (9)
- Copper ions and the regulation of (1996) (9)
- Manganese Homeostasis in Saccharomyces cerevisiae (2010) (8)
- Cu/Zn superoxide dismutase and the proton ATPase Pma1p of Saccharomyces cerevisiae. (2015) (8)
- Expanded role of the Cu‐sensing transcription factor Mac1p in Candida albicans (2020) (7)
- A role for Candida albicans superoxide dismutase enzymes in glucose signaling. (2018) (7)
- Sites of topoisomerase I action on X. laevis ribosomal chromatin: transcriptionally active rDNA has an approximately 200 bp repeating structure. (1988) (7)
- Ceruloplasmin as a source of Cu for a fungal pathogen. (2021) (4)
- The Transport and Intracellular Trafficking of Metal ions in Yeast (1999) (4)
- Speaking from the heart: systemic copper signaling. (2010) (3)
- Iron and Manganese Transporters in Yeast (2003) (3)
- Metals: setting a trap for copper. (2014) (3)
- Erratum: Mechanisms for activating Cu- and Zn-containing superoxide dismutase in the absence of the CCS Cu chaperone (Proceedings of the National Academy of Sciences of the United States of America (April 20, 2004) 101, 16 (5964-5969)) (2004) (2)
- cerevisiae Saccharomyces Lessons Learned from Manganese Transport and Trafficking : (2005) (2)
- THE RIGHT TO CHOOSE : MULTIPLE PATHWAYS FOR ACTIVATING Cu / Zn SUPEROXIDE DISMUTASE (2009) (1)
- Cdc42 regulates reactive oxygen species production in the pathogenic yeast Candida albicans (2021) (1)
- The crystal structure of SOD5: an unusual copper‐only superoxide dismutase (774.2) (2014) (1)
- The Irony of Cu-only Superoxide Dismutases in Fungal Pathogens (2017) (1)
- Mitochondrial Superoxide Mimics the Cellular Response To Nutrients in the Yeast Saccharomyces cerevisiae (2011) (1)
- Shining light on photosynthetic microbes and manganese-enriched rock varnish (2021) (0)
- Chaperones for Metalloproteins (2004) (0)
- Regulation of catalase gene expression by copper. (1992) (0)
- Motor neuron disease - SOD1 transgenic models (2000) (0)
- Genetically distinct components of copper transport in yeast (1992) (0)
- Structural Characterization of SOD5 Mutants from Candida albicans (2016) (0)
- Hepatobiliary manganese homeostasis is dynamic in the setting of illness in mice (2023) (0)
- Copper-only Superoxide Dismutases as Novel Drug Targets for Fungal Pathogens (2017) (0)
- Superhero superoxide dismutase (360.2) (2014) (0)
- Human SOD1 H80R variant, P212121 crystal form (2010) (0)
- Perspectives on the Mechanisms of Familial Amyotrophic Lateral Sclerosis Caused by Mutations in Superoxide Dismutase 1 (1997) (0)
- A molecular genetic approach to understanding superoxide dismutase function in a eukaryotic cell (1993) (0)
- SOD5 is the Prototype of a New Class of Cu-only Superoxide Dismutases (2014) (0)
- Candida Albicans FRE8 Encodes a Member of the NADPH Oxidase Family that Produces a Burst of ROS Important for Morphogenesis (2017) (0)
- Biochemical Analysis of CaurSOD4, a Potential Therapeutic Target for the Emerging Fungal Pathogen Candida auris. (2022) (0)
- Biophysical Characterization of Metal‐Deficient SOD5 (2015) (0)
- Two classes of extracellular Cu-only SODs for fungal pathogens (2018) (0)
- MECHANISMS OF COPPER ION HOMEOSTASIS IN YEAST (1993) (0)
- The Yin and Yang of copper during infection (2016) (0)
- Human SOD1 D124V Variant (2010) (0)
- Chemical warfare at the microorganismal level: a closer look at the SOD enzymes of pathogens (2018) (0)
- Engineering a Putative Zinc Binding Site in SOD5 (2016) (0)
- Species-specific activation of Cu/Zn SOD by its CCS copper chaperone in the pathogenic yeast Candida albicans (2013) (0)
- Iron toxicity and mitochondrial oxidative stress (2006) (0)
- Metallochaperones & Metal Ion Homeostasis (2006) (0)
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