Valerie Speirs
#145,373
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Professor of experimental pathology & oncology
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Valerie Speirsmedical Degrees
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Oncology
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Valerie Speirsbiology Degrees
Biology
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Pathology
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Medical Biology
Valerie Speirs's Degrees
- PhD Pathology Stanford University
- Doctorate Medicine Stanford University
Why Is Valerie Speirs Influential?
(Suggest an Edit or Addition)According to Wikipedia, Valerie Speirs is a Professor of Molecular Oncology at the University of Aberdeen. Her research aims to identify biomarkers of breast cancer to inform diagnosis and treatment. Education Speirs studied zoology at the University of Aberdeen. She completed her graduate studies at the University of Glasgow. She worked with Ian Freshney on cell culture and became interested in how cell culture systems can be used to model disease.
Valerie Speirs's Published Works
Published Works
- Choosing the right cell line for breast cancer research (2011) (1242)
- Relationship between quantitative estrogen and progesterone receptor expression and human epidermal growth factor receptor 2 (HER-2) status with recurrence in the Arimidex, Tamoxifen, Alone or in Combination trial. (2008) (420)
- Matrix metalloproteinases and angiogenesis (2000) (397)
- Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer (2013) (377)
- Comparison of microfluidic digital PCR and conventional quantitative PCR for measuring copy number variation (2012) (359)
- Breast cancer cell lines: friend or foe? (2003) (339)
- Increased expression of estrogen receptor beta mRNA in tamoxifen-resistant breast cancer patients. (1999) (260)
- Coexpression of Estrogen Receptor α and β: Poor Prognostic Factors in Human Breast Cancer? (1999) (241)
- Phyto-oestrogens and breast cancer chemoprevention (2004) (217)
- Reduced expression of oestrogen receptor β in invasive breast cancer and its re‐expression using DNA methyl transferase inhibitors in a cell line model (2003) (215)
- Nuclear and Cytoplasmic Expression of ERβ1, ERβ2, and ERβ5 Identifies Distinct Prognostic Outcome for Breast Cancer Patients (2008) (201)
- Expression of cytokine messenger RNA in normal and neoplastic human breast tissue: Identification of interleukin‐8 as a potential regulatory factor in breast tumours (1997) (150)
- Relationship of Extreme Chromosomal Instability with Long-term Survival in a Retrospective Analysis of Primary Breast Cancer (2011) (144)
- Distinct expression patterns of ERα and ERβ in normal human mammary gland (2002) (142)
- The rising incidence of male breast cancer (2009) (141)
- Evaluation of seven oestrogen receptor β antibodies for immunohistochemistry, western blotting, and flow cytometry in human breast tissue (2002) (139)
- Loss of expression of oestrogen receptor beta in colon cancer and its association with Dukes' staging. (2005) (138)
- Oestrogen receptor β: what it means for patients with breast cancer (2004) (130)
- Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness (2016) (121)
- Male breast carcinoma: increased awareness needed (2011) (121)
- Combined analysis of eIF4E and 4E-binding protein expression predicts breast cancer survival and estimates eIF4E activity (2009) (117)
- A comparative biomarker study of 514 matched cases of male and female breast cancer reveals gender-specific biological differences (2012) (114)
- In vivo models in breast cancer research: progress, challenges and future directions (2017) (113)
- Estrogen receptor {beta}1 expression is regulated by miR-92 in breast cancer. (2010) (107)
- MiR-26b is down-regulated in carcinoma-associated fibroblasts from ER-positive breast cancers leading to enhanced cell migration and invasion (2013) (103)
- Short-term primary culture of epithelial cells derived from human breast tumours. (1998) (100)
- Immunohistochemical detection of ERβ in breast cancer: towards more detailed receptor profiling? (2001) (96)
- Distinct expression patterns of ER alpha and ER beta in normal human mammary gland. (2002) (88)
- Metastatic-niche labelling reveals parenchymal cells with stem features (2019) (87)
- Clinical and functional significance of loss of caveolin‐1 expression in breast cancer‐associated fibroblasts (2012) (87)
- The prognostic significance of tumour–stroma ratio in oestrogen receptor-positive breast cancer (2013) (87)
- Genetic changes in breast cancer detected by comparative genomic hybridisation (2000) (84)
- Mechanisms of FGFR3 actions in endocrine resistant breast cancer (2012) (83)
- Small is beautiful: microRNAs and breast cancer—where are we now? (2008) (80)
- Coexpression of estrogen receptor alpha and beta: poor prognostic factors in human breast cancer? (1999) (77)
- Expression of alternatively spliced estrogen receptor alpha mRNAs is increased in breast cancer tissues (2001) (76)
- Loss of CSMD1 expression is associated with high tumour grade and poor survival in invasive ductal breast carcinoma (2010) (75)
- Expression of COX-2, NF-κB-p65, NF-κB-p50 and IKKα in malignant and adjacent normal human colorectal tissue (2009) (74)
- CAPG and GIPC1: Breast Cancer Biomarkers for Bone Metastasis Development and Treatment (2016) (74)
- Oestrogen receptor β in breast cancer: good, bad or still too early to tell? (2002) (73)
- Identification of wild-type and exon 5 deletion variants of estrogen receptor beta in normal human mammary gland. (2000) (73)
- Vascular endothelial growth factor in premenopausal women--indicator of the best time for breast cancer surgery? (1998) (68)
- Activity and gene expression of 17β-hydroxysteroid dehydrogenase type I in primary cultures of epithelial and stromal cells derived from normal and tumourous human breast tissue: the role of IL-8 (1998) (67)
- Properties and characteristics of the dyes injected to assist axillary sentinel node localization in breast surgery. (2006) (66)
- Cell biology of pulmonary neuroepithelial bodies—validation of an in vitro model. I. Effects of hypoxia and Ca2+ ionophore on serotonin content and exocytosis of dense core vesicles (1993) (66)
- Production of VEGF and expression of the VEGF receptors Flt-1 and KDR in primary cultures of epithelial and stromal cells derived from breast tumours (1999) (65)
- Oestrogen receptor beta: what it means for patients with breast cancer. (2004) (64)
- Prognostic significance of oestrogen receptor β in breast cancer (2000) (64)
- New perspectives into the biological and clinical relevance of oestrogen receptors in the human breast (2007) (64)
- A Rac/Cdc42 exchange factor complex promotes formation of lateral filopodia and blood vessel lumen morphogenesis (2015) (60)
- Insulin-like growth factor - oestradiol crosstalk and mammary gland tumourigenesis. (2013) (57)
- A Multi-Centre Investigation Towards Reaching a Consensus on the Immunohistochemical Detection of ERβ in Archival Formalin-fixed Paraffin Embedded Human Breast Tissue (2005) (56)
- The manufacture and assessment of tissue microarrays: suggestions and criteria for analysis, with breast cancer as an example (2012) (52)
- CERT depletion predicts chemotherapy benefit and mediates cytotoxic and polyploid‐specific cancer cell death through autophagy induction (2012) (52)
- Carcinoembryonic Antigen Cell Adhesion Molecule 6 Predicts Breast Cancer Recurrence following Adjuvant Tamoxifen (2008) (52)
- Differential response to phytoestrogens in endocrine sensitive and resistant breast cancer cells in vitro (2006) (51)
- Steroid hormone receptor expression in male breast cancer. (2006) (51)
- The practicalities of using tissue slices as preclinical organotypic breast cancer models (2012) (51)
- Cytokine expression in human anterior pituitary adenomas (1996) (50)
- Promoter switch: a novel mechanism causing biallelic PEG1/MEST expression in invasive breast cancer. (2002) (48)
- Oestrogen receptor beta in breast cancer: good, bad or still too early to tell? (2002) (45)
- Pattern of expression of genes linked to epigenetic silencing in human breast cancer. (2006) (44)
- Constitutive co‐expression of estrogen and progesterone receptor mRNA in human meningiomas by RT‐PCR and response of in vitro cell cultures to steroid hormones (1997) (44)
- Management and 5-year outcomes in 9938 women with screen-detected ductal carcinoma in situ: the UK Sloane Project. (2018) (44)
- Characterisation of male breast cancer: a descriptive biomarker study from a large patient series (2017) (44)
- Phosphorylation of estrogen receptor beta at serine 105 is associated with good prognosis in breast cancer. (2010) (42)
- Expression of oestrogen receptor beta isoforms is regulated by transcriptional and post-transcriptional mechanisms. (2010) (41)
- Obesity and male breast cancer: provocative parallels? (2015) (39)
- Expression and secretion of TGF-beta isoforms and expression of TGF-beta-receptors I, II and III in normal and neoplastic human breast. (1999) (38)
- The Hippo transducers TAZ/YAP and their target CTGF in male breast cancer (2016) (38)
- Microcephalin is a new novel prognostic indicator in breast cancer associated with BRCA1 inactivation (2011) (37)
- In vivo and in vitro expression of steroid-converting enzymes in human breast tumours: associations with interleukin-6 (1999) (36)
- Genetic events during the transformation of a tamoxifen-sensitive human breast cancer cell line into a drug-resistant clone. (2001) (36)
- Differential regulation of oestrogen receptor β isoforms by 5′ untranslated regions in cancer (2009) (36)
- Inflammatory breast cancer: time to standardise diagnosis assessment and management, and for the joining of forces to facilitate effective research (2015) (35)
- Prognostic significance of oestrogen receptor beta in breast cancer. (2000) (35)
- Direct activation of oestrogen receptor- α by interleukin-6 in primary cultures of breast cancer epithelial cells (2000) (34)
- Identification of MAGEA antigens as causal players in the development of tamoxifen-resistant breast cancer (2014) (33)
- Evidence for transcriptional activation of ERalpha by IL-1beta in breast cancer cells. (1999) (33)
- Changes in expression of steroid receptors, their downstream target genes and their associated co-regulators during the sequential acquisition of tamoxifen resistance in vitro. (2007) (31)
- Expression of prostate specific antigen in male breast cancer (2004) (31)
- Role of gonadotropin-releasing hormone analogues in metastatic male breast cancer: results from a pooled analysis (2015) (30)
- Identification and validation of DOCK4 as a potential biomarker for risk of bone metastasis development in patients with early breast cancer (2019) (29)
- Three‐dimensional reconstruction of ductal carcinoma in situ with virtual slides (2015) (29)
- A novel cell array technique for high-throughput, cell-based analysis (2005) (29)
- A comparative study of genome-wide SNP, CGH microarray and protein expression analysis to explore genotypic and phenotypic mechanisms of acquired antiestrogen resistance in breast cancer (2008) (27)
- Isolation and culture of neuroendocrine cells from fetal rabbit lung using immunomagnetic techniques. (1992) (27)
- ERβ1 represses FOXM1 expression through targeting ERα to control cell proliferation in breast cancer. (2011) (27)
- Down-Regulation of miR-92 in Breast Epithelial Cells and in Normal but Not Tumour Fibroblasts Contributes to Breast Carcinogenesis (2015) (25)
- Interactive effects of interleukin-6, 17β-estradiol and progesterone on growth and 17β-hydroxysteroid dehydrogenase activity in human breast carcinoma cells (1993) (24)
- The potential role of ERβ isoforms in the clinical management of breast cancer (2008) (23)
- Development and characterisation of a 3D multi-cellular in vitro model of normal human breast: a tool for cancer initiation studies (2015) (23)
- Collagenase III: A superior enzyme for complete disaggregation and improved viability of normal and malignant human breast tissue (1996) (23)
- A comparative study of cytokine gene transcripts in normal and malignant breast tissue and primary cell cultures derived from the same tissue samples (1996) (23)
- Androgen receptor and antiandrogen therapy in male breast cancer. (2015) (22)
- Interleukin-6 (IL-6) production and cell growth of cultured human ameningiomas:- Interactions with interleukin-1β (IL-1β) and interleukin-4 (IL-4) in vitro (1994) (22)
- Identification of stage-specific breast markers using quantitative proteomics. (2013) (21)
- Activity of interferon alpha, interleukin 6 and insulin in the regulation of differentiation in A549 alveolar carcinoma cells. (1995) (21)
- Antiandrogen therapy in metastatic male breast cancer: results from an updated analysis in an expanded case series (2014) (21)
- Differential Expression of MicroRNAs in Breast Cancers from Four Different Ethnicities (2018) (20)
- An overview of culture and isolation methods suitable for in vitro studies on pulmonary neuroendocrine cells (1993) (20)
- Paracrine control of differentiation in the alveolar carcinoma, A549, by human foetal lung fibroblasts. (1991) (19)
- PSMD9 expression predicts radiotherapy response in breast cancer (2014) (18)
- Loss of CSMD1 expression disrupts mammary duct formation while enhancing proliferation, migration and invasion. (2017) (18)
- Raman spectroscopy: current applications in breast cancer diagnosis, challenges and future prospects (2021) (18)
- The anti-estrogen tamoxifen blocks the stimulatory effects of interleukin-6 on 17β-hydroxysteroid dehydrogenase activity in MCF-7 cells (1993) (18)
- The evolving role of oestrogen receptor beta in clinical breast cancer (2008) (17)
- Reflections on the upsurge of virtual cancer conferences during the COVID-19 pandemic (2020) (17)
- Lack of CD151/integrin α3β1 complex is predictive of poor outcome in node-negative lobular breast carcinoma: opposing roles of CD151 in invasive lobular and ductal breast cancers (2015) (17)
- The potential utility of geminin as a predictive biomarker in breast cancer (2013) (17)
- Deregulation of IGF-binding proteins -2 and -5 contributes to the development of endocrine resistant breast cancer in vitro (2016) (16)
- Current and Emerging 3D Models to Study Breast Cancer. (2019) (16)
- Oestrogen receptor beta immunohistochemistry: time to get it right? (2008) (15)
- Oestrogen receptor beta: how should we measure this? (2002) (15)
- A Case-Matched Gender Comparison Transcriptomic Screen Identifies eIF4E and eIF5 as Potential Prognostic Markers in Male Breast Cancer (2016) (15)
- Regulation of estrogen receptor β1 expression in breast cancer by epigenetic modification of the 5' regulatory region. (2013) (14)
- Oestrogen receptor β (ERβ) regulates osteogenic differentiation of human dental pulp cells (2017) (14)
- Functional inactivation of the oestrogen receptor by the antioestrogen, ZM 182780, sensitises tumour cells to reactive oxygen species. (1999) (14)
- Conditions of the male breast: Gynaecomastia and male breast cancer (Review). (2009) (14)
- Molecular cytogenetic analysis of breast cancer cell lines (2000) (13)
- Male breast cancer: an update (2021) (13)
- An Evaluation of Matrix-Containing and Humanised Matrix-Free 3-Dimensional Cell Culture Systems for Studying Breast Cancer (2016) (13)
- Breast cancer: Investment biobanking—increased returns from tissue samples (2013) (12)
- Analysis of the ATR-Chk1 and ATM-Chk2 pathways in male breast cancer revealed the prognostic significance of ATR expression (2017) (12)
- The Sharing Experimental Animal Resources, Coordinating Holdings (SEARCH) Framework: Encouraging Reduction, Replacement, and Refinement in Animal Research (2017) (12)
- Oestrogen receptor β immunohistochemistry: time to get it right? (2008) (12)
- 17Beta-hydroxysteroid dehydrogenase type 1, 2, 3, and 4 expression and enzyme activity in human anterior pituitary adenomas. (1999) (12)
- Stanniocalcin 2 expression is associated with a favourable outcome in male breast cancer (2018) (12)
- Clinical importance of estrogen receptor beta isoforms in breast cancer. (2008) (12)
- Expression of regulators of mitotic fidelity are associated with intercellular heterogeneity and chromosomal instability in primary breast cancer (2014) (11)
- Preclinical models of glioblastoma: limitations of current models and the promise of new developments (2021) (11)
- Prognostic and predictive value of ERβ1 and ERβ2 in the Intergroup Exemestane Study (IES)-first results from PathIES†. (2015) (11)
- Epithelial–mesenchymal interactions in breast cancer: evidence for a role of nuclear localized β‐catenin in carcinoma‐associated fibroblasts (2011) (11)
- The value of archival tissue blocks in understanding breast cancer biology (2013) (10)
- Interleukin‐3: A putative protective factor against breast cancer which is secreted by male but not female breast fibroblasts (1995) (10)
- Problems (and solutions) in the study of male breast cancer (2010) (10)
- 91st Annual Meeting of the American Association for Cancer Research (2000) (10)
- Growth factor regulation of 17 beta-hydroxysteroid dehydrogenase activity in a human ovarian cell line: modulation by 17 beta-estradiol. (1993) (10)
- Pulmonary neuroendocrine cells in cultures of human infant airway mucosa from postmortem tissues. (1996) (10)
- SEARCHBreast: a new resource to locate and share surplus archival material from breast cancer animal models to help address the 3Rs (2016) (9)
- Gene Expression of ERβ Isoforms in Laser Microdissected Human Breast Cancers: Implications for Gene Expression Analyses (2009) (9)
- Tissue microarrays--big potential from small samples (review). (2004) (9)
- External validation of the ImmunoRatio image analysis application for ERα determination in breast cancer (2013) (9)
- Localization of MOC-1 cell surface antigen in small-cell lung carcinoma cell lines: an immunohistochemical and immunoelectron microscopic study. (1993) (9)
- Angiogenesis in breast cancer: how should we measure this? (Review). (2005) (8)
- Interleukin-6 (IL-6) production and cell growth of cultured human ameningiomas:-interactions with interleukin-1 beta (IL-1 beta) and interleukin-4 (IL-4) in vitro. (1994) (8)
- Estrogen receptor β: putting a positive into triple negative breast cancer? (2013) (8)
- Incidence of male breast cancer in Scotland over a twenty-five-year period (1992-2017). (2020) (8)
- Author Correction: Metastatic-niche labelling reveals parenchymal cells with stem features (2019) (8)
- RT‐PCR DETECTION OF CYTOKINE TRANSCRIPTS IN A SERIES OF CULTURED HUMAN MENINGIOMAS (1996) (8)
- Animal research: Share surplus animal tissue (2015) (8)
- 3-D Tissue Modelling and Virtual Pathology as New Approaches to Study Ductal Carcinoma In Situ (2015) (7)
- SEARCHBreast Workshop Proceedings: 3D Modelling of Breast Cancer (2015) (7)
- Identification of differentially expressed genes in matched formalin‐fixed paraffin‐embedded primary and metastatic melanoma tumor pairs (2012) (7)
- Clinicians' guide to microarrays. (2006) (7)
- Systemic and neurologic abnormalities distinguish the lysosomal disorders sialidosis and galactosialidosis in mice (2002) (7)
- Intracellular Flow Cytometric Analysis of Primary Cultured Breast Tumor Cells (2002) (7)
- Association between AXL, Hippo Transducers, and Survival Outcomes in Male Breast Cancer (2017) (7)
- Advances in the development of improved animal-free models for use in breast cancer biomedical research (2017) (6)
- HMG-CoAR expression in male breast cancer: relationship with hormone receptors, Hippo transducers and survival outcomes (2016) (6)
- Estrogen Receptor β 1 Expression Is Regulated by miR-92 in Breast Cancer (2010) (6)
- Adding value to rare tissue samples donated to biobanks: characterisation of breast tissue and primary cell cultures obtained from a female-to-male transgender patient (2015) (6)
- MicroRNA-495/TGF-β/FOXC1 axis regulates multidrug resistance in metaplastic breast cancer cells. (2021) (6)
- Review Phyto-oestrogens and breast cancer chemoprevention (2004) (5)
- Advances in Brief Increased Expression of Estrogen Receptor b mRNA in Tamoxifen-resistant Breast Cancer Patients 1 (1999) (5)
- Primary Culture of Human Mammary Tumor Cells (2005) (5)
- Male versus female breast cancer: a comparative study of 523 matched cases reveals differences behind similarity (2010) (5)
- Characterising the adipose-inflammatory microenvironment in male breast cancer. (2018) (5)
- Towards a-scan imaging via Ultrasonic Vibration Potential measurements (2011) (4)
- The Estrogen Receptors α, β, and βcx (2005) (4)
- The estrogen receptors alpha, beta, and beta cx. (2005) (4)
- A Review of International Biobanks and Networks: Success Factors and Key Benchmarks-A 10-Year Retrospective Review. (2019) (4)
- CIP2A expression predicts recurrences of tamoxifen-treated breast cancer (2017) (4)
- SEARCHBreast: a new online resource to make surplus material from in vivo models of breast cancer visible and accessible to researchers (2016) (4)
- Role of ERβ in Clinical Breast Cancer. (2009) (4)
- Estrogen receptor regulation: don’t forget translation (2010) (4)
- Reponse to: comment on, ‘Tumour-stroma ratio (TSR) in oestrogen-positive breast cancer patients' (2014) (4)
- Downregulation of 15-hydroxyprostaglandin dehydrogenase during acquired tamoxifen resistance and association with poor prognosis in ERα-positive breast cancer (2020) (4)
- Interactive effects of interleukin-6, 17 beta-estradiol and progesterone on growth and 17 beta-hydroxysteroid dehydrogenase activity in human breast carcinoma cells. (1993) (3)
- Role of miR-26b in carcinoma-associated fibroblasts and effect on migration and invasion of breast cancer epithelial cells (2014) (3)
- The Cellular and Molecular Pathology Biobanking Sample Quality Improvement Tool: A Guide for Improving the Quality of Tissue Collections for Biomedical Research and Clinical Trials in Cancer. (2020) (3)
- Quality Considerations When Using Tissue Samples for Biomarker Studies in Cancer Research (2021) (3)
- Rapid and irreversible loss of estrogen receptor in human osteoblast-like cells following culture in phenol red-free medium (1997) (3)
- Steroid hormone receptor expression in breast cancer stroma (2014) (3)
- Phosphorylation of Estrogen Receptor β at Serine 105 in Primary Breast Cancer. (2009) (3)
- A Global View of Breast Tissue Banking. (2015) (3)
- Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer (2013) (3)
- Investigating and critically appraising the expression and potential role of androgen receptor in breast carcinoma (2011) (3)
- Hormone receptors in defining breast cancer prognosis—time for a rethink? (2007) (3)
- miR-92 Is a Novel Regulator of ERβ1 Expression in Breast Cancer. (2009) (3)
- Exploring the influence of rural residence on uptake of organized cancer screening - A systematic review of international literature. (2021) (3)
- Analysis of the Clinical Advancements for BRCA-Related Malignancies Highlights the Lack of Treatment Evidence for BRCA-Positive Male Breast Cancer (2022) (2)
- Comparative rat and human mammary histopathology (2000) (2)
- A biobank perspective on use of tissue samples donated by trial participants. (2022) (2)
- MicroRNA-92 targets the 3' untranslated region of ERβ1 mRNA and post-transcriptionally regulates its expression in breast cancer (2010) (2)
- Preoperative serum VEGF in primary breast cancer patients — Its relation with oestrogen receptor status and cancer type (1998) (2)
- Wnt signalling in mammary carcinogenesis (2002) (2)
- Expression of estrogen receptor β — comparison between invasive lobular and ductal cancers of the breast (2001) (2)
- Downregulation of 15-hydroxyprostaglandin dehydrogenase in hormone-resistant breast cancer (2008) (2)
- Methylation Status of Promoters 0K, 0N and a Newly Identified Promoter Regulate ERβ1 Expression in Breast Cancer. (2009) (2)
- Reduced MCPH1 expression in breast cancer and response to chemotherapy (2010) (2)
- Radiotherapy biobanking: current landscape, opportunities, challenges, and future aspirations (2021) (2)
- Perspective: Not just for women (2012) (2)
- Loss of CSMD1 disrupts mammary epithelial morphogenesis (2010) (2)
- 55O_PRPROGNOSTIC AND PREDICTIVE VALUE OF IHC4 AND ERB1 IN THE INTERGROUP EXEMESTANE STUDY (IES) - ON BEHALF OF THE PATHIES INVESTIGATORS (2013) (2)
- Differential expression of cell adhesion molecules in phenotypic variants of the small cell lung carcinoma cell line NCI-H69 (1998) (2)
- Author Correction: Pan-cancer image-based detection of clinically actionable genetic alterations (2020) (2)
- Evaluation of applying IHC4 as a prognostic model in the translational study of Intergroup Exemestane Study (IES): PathIES (2017) (2)
- Rho GTPase signaling and role of the Rac1 exchange factor DOCK4 in GBM invasion and vascular growth (2018) (2)
- British Cancer Research Meeting, 30 June-3 July 2002, Glasgow (2002) (2)
- Modelling the Molecular Pathology of Breast Cancer Initiation (2015) (1)
- Tamoxifen and angiogenesis (2001) (1)
- Correspondence re: K. Heer et al., serum vascular endothelial growth factor in breast cancer: its relation with cancer type and estrogen receptor status. Clin. Cancer Res., 7: 3491-3494, 2001. (2003) (1)
- Pancreas Cancer Molecular Targets for Therapy (2011) (1)
- Correspondence re: S. A. W. Fuqua et al., Estrogen receptor beta protein in human breast cancer: correlation with clinical tumor parameters. Cancer Res.,63: 2434-2439, 2003. (2003) (1)
- Editorial The evolving role of oestrogen receptor β in clinical breast cancer (2008) (1)
- Axillary management in T1-3N1M0 breast cancer patients with needle biopsy proven nodal metastases at presentation after neoadjuvant chemotherapy (ATNEC). (2021) (1)
- Treatment and outcomes from a large, prospective, national longitudinal cohort study of screen detected ductal carcinoma in situ (DCIS). (2016) (1)
- NM23-H2, an ERβ Associated Protein, as a Prognostic Marker in Breast Cancer. (2009) (1)
- Progress towards unlocking the secrets of oestrogen receptor beta in breast cancer (2006) (1)
- Loss of CSMD 1 expression disrupts mammary duct formation while enhancing proliferation , migration and invasion (2017) (1)
- Abstract OT1-04-01: ATNEC: A multi-centre, randomised trial investigating whether axillary treatment can be avoided in T1-3N1M0 breast cancer patients with no residual cancer in the lymph glands after neoadjuvant chemotherapy (clinicaltrials.gov: nct04109079) (2022) (1)
- Adverse effects of dyes used in sentinel node biopsy on immunocytochemical determination of hormone receptors in breast cancer cells (2007) (1)
- Cytokine Expression in Normal and Neoplastic Breast Tissue (1995) (1)
- VEGF — cyclical variation may have implications in benign breast disease (1997) (1)
- Abstract B127: Loss of miR-92 expression in breast epithelial cells is associated with cancer progression (2013) (1)
- Biobanking in radiotherapy trials — a challenge to the clinical research community (2021) (1)
- Introducing SEARCHBreast: a virtual resource to facilitate sharing of surplus animal material developed for breast cancer research (2016) (1)
- PtdIns 3-kinase (2011) (1)
- Barriers to the release of human tissue for clinical trials research in the UK: a national survey of cellular pathology laboratories on behalf of the National Cancer Research Institute’s Cellular Molecular Pathology (CM-Path) initiative (2018) (1)
- Introducing Viewpoints – Breast Cancer Research's new style literature appraisal service (2003) (1)
- Pre-Clinical Modeling of Breast Cancer: Which Model to Choose? (2013) (1)
- Analysis of the ATR-Chk1 and ATM-Chk2 pathways in male breast cancer revealed the prognostic significance of ATR expression (2017) (0)
- OP52THE ROLE OF DOCK4 IN CANCER CELL INVASION AND ANGIOGENESIS IN BREAST CANCER BRAIN METASTASES (2015) (0)
- Defining genomic, transcriptomic, proteomic, epigenetic, and phenotypic biomarkers with prognostic capability in male breast cancer: a systematic review. (2023) (0)
- Ovarian hormones effect VEGF expression in breast cancer cells (1998) (0)
- Articles selected in September 2004 (2004) (0)
- P5-21-03: The Breast Cancer Campaign Tissue Bank. (2011) (0)
- Advances in the development of improved animal-free models for use in breast cancer biomedical research (2017) (0)
- O-66 Reduced MCPH1 expression in breast cancer is associated with reduced survival in ductal carcinomas (2010) (0)
- Changes in ER beta versus ER alpha in short-term studies of antiestrogen therapies. (2009) (0)
- Comparative Biomarker Analysis in 523 Matched Male and Female Breast Cancers. (2009) (0)
- Articles selected in December 2003 (2004) (0)
- Efficient Labeling of Estrogen Receptor α Inside Cells using Affimer, an Antibody Mimetic (2020) (0)
- Validation of a 3D perfused cell culture platform as a tool for humanised preclinical drug testing in breast cancer using established cell lines and patient-derived tissues (2023) (0)
- Labeling of a Mutant Estrogen Receptor with an Affimer in a Breast Cancer Cell Line. (2022) (0)
- CIP 2 A expression predicts recurrences of tamoxifen-treated breast cancer (2017) (0)
- P3 Evaluating the expression of HMGCS2 in human breast cancer relapses (2007) (0)
- Chromosomal alterations associated with transformation of a tamoxifen-sensitive cell line into its drug resistant clone (2001) (0)
- Articles selected from Faculty of 1000 in November 2003 (2003) (0)
- The Stimulatory Effects of Paracrine Factors on 17-Beta Hydroxysteroid Dehydrogenase Activity are Blocked by tamoxifen (1993) (0)
- Modelling breast cancer in a three-dimensional heterotypic culture system (2010) (0)
- Articles selected from Faculty of 1000 in March 2003 (2003) (0)
- Proliferative regulation of human breast cancer cells by dietary phytoestrogens: Mechanisms of estrogen receptor-mediated signalling (2003) (0)
- O-36 The potential role of ER beta in stromal regulation of mammary carcinogenesis (2007) (0)
- SEARCHBreast; making surplus material from in vivo models of breast cancer available for research (2016) (0)
- CEACAM: A potential novel predictor of breast cancer recurrence (2006) (0)
- Gene expression profiling (2002) (0)
- P152: Incidence of male breast cancer in Scotland over a twenty-five-year period (1992 - 2017) (2020) (0)
- Specific cellular labeling of a clinically important estrogen receptor alpha mutant, Y537S, with an affimer (2022) (0)
- Nuclear receptor profiling predicts chemical disruptors as risk factors for developing breast cancer (2019) (0)
- A gap analysis for breast cancer research: identifying translational priorities (2013) (0)
- Prognostic significance of immunohistochemical markers in endometrial cancer treated with chemotherapy. (2009) (0)
- Population Candidate Gene Association Study (2011) (0)
- The prognostic significance of eukaryotic initiation factors 4E and 5 in male breast cancer (2016) (0)
- Male Breast Cancer (2019) (0)
- Articles selected from Faculty of 1000 in May 2003 (2003) (0)
- O-9 Loss of CSMD1 expression disrupts cell morphology and mammary duct formation while enhancing proliferation, migration and invasion (2010) (0)
- SEARCHBreast: a new online resource to make surplus material from in vivo models of breast cancer visible and accessible to researchers (2016) (0)
- 22. Geminin: A prognostic marker in breast cancer (2012) (0)
- Alterations in expression levels of ER subtypes and their coregulators in endocrine resistant breast cancer (2002) (0)
- MCPH1, a potential predictor for response to cancer chemotherapy (2008) (0)
- Signalling by Steroid Receptors (2007) (0)
- Articles selected from Faculty of 1000 in September 2003 (2003) (0)
- OPTIMA: New research project aims to improve treatment for patients with prostate, breast and lung cancer through artificial intelligence (2023) (0)
- Articles selected in February 2004 (2004) (0)
- Characterisation of the tumour suppressor gene ZAC in breast tissue (2006) (0)
- Gene expression signatures may predict clinical outcome (2002) (0)
- A comparative study of the prognostic role of KI67 and geminin in breast cancer (2013) (0)
- Author ' s response to reviews Title : Obesity and Male Breast Cancer : Provocative Parallels ? (2015) (0)
- Integrative, In Silico and Comparative Analysis of Breast Cancer Secretome Highlights Invasive-Ductal-Carcinoma-Grade Progression Biomarkers (2022) (0)
- Hormone Receptors in Breast Cancer (2019) (0)
- Tspan6 stimulates the chemoattractive potential of breast cancer cells for B cells in an EV- and LXR-dependent manner. (2023) (0)
- Poor overall survival in male breast cancer patients negative for CK18 and CK19 (2017) (0)
- Placental autophagy regulates trophoblast survival in placental dysfunction during pregnancy complications (2017) (0)
- Tamoxifen, angiogenesis, oestrogens and animal models (2001) (0)
- Com-1 in breast cancer (2000) (0)
- Tamoxifen-resistant Breast Cancer Patients mRNA in β Increased Expression of Estrogen Receptor (2013) (0)
- Generation of human tumors in vitro (1999) (0)
- CEACAM6 is a powerful prognostic marker of breast cancer recurrence (2007) (0)
- Endocrine response: Is CGAthe key? (2001) (0)
- Stromal fibroblasts with nuclear β-catenin are present within breast tumours and increase proliferation and invasion of epithelial breast cancer cells (2008) (0)
- SUM-159PT: an ER-independent breast cancer model (2000) (0)
- Abstract P4-19-02: Early experience of patient donation and researcher use of tissues donated to a national breast cancer tissue bank (2013) (0)
- Down-regulation of type I collagen by breast tumour cells (1999) (0)
- Articles selected in May 2004 (2004) (0)
- Ang1 in breast cancer (2000) (0)
- Abstract P6-02-06: A 3D tri-culture model of normal mammary gland. A tool for breast cancer initiation studies (2012) (0)
- INSPIRE INTERNATIONAL SCHOLARSHIPS (2019) (0)
- Corrigendum (2018) (0)
- Management of breast cancer in an Asian man with post-traumatic stress disorder: a case report (2016) (0)
- PSMD9 expression predicts radiotherapy response in breast cancer (2014) (0)
- The effect of the dyes used in sentinel lymph node biopsy localization on immunocytochemical determination of hormonal receptors in MCF-7 breast cancer cell line (2006) (0)
- Tissue microarray validation (2001) (0)
- NALISATION AS A DELIVERY TOOL TO IMPROVE CHEMOTHERAPY FOR ORAL SQUAMOUS CELL CARCINOMA (2013) (0)
- The CM-Path Biobanking Sample Quality Improvement Tool: A Guide for Improving the Quality of Tissue Collections for Biomedical Research and Clinical Trials in Cancer (2020) (0)
- Variability In Plasma VEGF: Interaction Of Menstrual Cycle Phase And Exercise Intensity (2005) (0)
- O-5 Carcinoembryonic antigen cell adhesion molecule (CEACAM6) predicts breast cancer recurrence following adjuvant tamoxifen (2007) (0)
- Beta-catenin in breast cancer (2000) (0)
- Abstract P2-11-07: Proteins predictive of bone metastasis development in breast cancer patients (2013) (0)
- Articles selected in July 2004 (2004) (0)
- Articles selected from Faculty of 1000 in July 2003 (2003) (0)
- Normal mammary epithelial cells escape of senescence (2001) (0)
- The SEARCHBreast portal: a virtual bioresource to facilitate the sharing of surplus animal materials derived from breast cancer studies (2016) (0)
- The Molecular Pathology of Male Breast Cancer (2015) (0)
- Morphological Features and Immunohistochemical Profiling of Male Breast Gynaecomastia; A Large Tissue Microarray Study (2022) (0)
- Mammaglobin as a marker in breast cancer (2000) (0)
- Comparing the Plasma and Urine of Untreated, Post-Menopausal, Female Breast Cancer Patients to Those of Normal controls, Using 1H-NMR-Based Metabonomics (2017) (0)
- Attitudes of female staff and students from two United Kingdom Medical Schools towards donating normal healthy breast tissue and blood samples for biomedical research (2017) (0)
- ‘Stanniocalcin 2 expression is associated with a favourable outcome in male breast cancer’ (2019) (0)
- Early Experience of consenting patients to donate to a breast cancer tissue bank (2013) (0)
- Characterisation of male breast cancer (2017) (0)
- Abstract P4-19-05: Breast cancer campaign tissue bank human cell culture programme: Generating new biomaterials for breast research (2013) (0)
- VEGF and radiotherapy in node-negative breast cancer (1999) (0)
- 84. Regulation of differentiation in lung carcinoma: paracrine control by glucocorticoids and lung fibroblasts (1992) (0)
- BPA and risk assessment. (2020) (0)
- Abstract OT-04-01: Axillary management in T1-3N1M0 breast cancer patients with needle biopsy proven nodal metastases at presentation after neoadjuvant chemotherapy - ATNEC (ClinicalTrials.gov NCT04109079) (2021) (0)
- Articles selected from Faculty of 1000 in January 2003 (2003) (0)
- Estrogen receptor beta--which one and where should we draw the line? (2006) (0)
- Interleukin-1alpha: the key to polycystic ovarian syndrome? (2007) (0)
- Adding value to rare tissue samples donated to biobanks: characterisation of breast tissue and primary cell cultures obtained from a female-to-male transgender patient (2014) (0)
- Membrane oestrogen receptor (2001) (0)
- ER variants in breast cancer (2000) (0)
- SEARCHBreast: An online resource designed to increase the efficiency of using materials derived from breast cancer studies in animals (2016) (0)
- Alternative 5' untranslated regions regulate estrogen receptor beta expression in breast carcinogenesis. (2009) (0)
- Primary Cancer Site (2011) (0)
- Expression of Interleukin-3 (IL-3) Transcripts in a Series of Cultured Human Meningiomas: Effect of IL-3 on Meningioma Growth in Vitro (1994) (0)
- O-34 Nuclear and cytoplasmic ER beta2 expression identifies distinct prognostic outcome in breast cancer patients (2007) (0)
- Telomerase inhibition reduces cell growth (1999) (0)
- Authors' reply (2003) (0)
- Tamoxifen and response (2000) (0)
- Abstract P1-12-12: The insulin like growth factor axis and development of tamoxifen resistance in breast cancer (2015) (0)
- ErbB-receptors in antiestrogen resistance (2000) (0)
- Estrogen receptor β—which one and where should we draw the line? (2006) (0)
- Tamoxifen-resistant breast carcinoma xenograft (2000) (0)
- Abstract 2505: Expression profiling of cofilin-1 in breast cancer cell lines and biopsies. (2013) (0)
- Apoptosis and caspases in breast cancer (1999) (0)
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