Vanessa M. Hirsch
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Canadian-American veterinary pathologist and scientist
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Vanessa M. Hirsch's Degrees
- Bachelors Biology University of British Columbia
- Doctorate Veterinary Medicine University of Guelph
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(Suggest an Edit or Addition)According to Wikipedia, Vanessa M. Hirsch is a Canadian-American veterinary pathologist and scientist. She is a senior investigator and chief of the nonhuman primate virology section at the National Institute of Allergy and Infectious Diseases. Hirsch researches AIDS pathogenesis, the evolution and origins of primate lentiviruses, and HIV vaccine development.
Vanessa M. Hirsch's Published Works
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Published Works
- An African primate lentivirus (SIVsmclosely related to HIV-2 (1989) (780)
- Vaccine Protection Against Acquisition of Neutralization-Resistant SIV Challenges in Rhesus Monkeys (2011) (481)
- Damaged Intestinal Epithelial Integrity Linked to Microbial Translocation in Pathogenic Simian Immunodeficiency Virus Infections (2010) (461)
- Macrophage are the principal reservoir and sustain high virus loads in rhesus macaques after the depletion of CD4+ T cells by a highly pathogenic simian immunodeficiency virus/HIV type 1 chimera (SHIV): Implications for HIV-1 infections of humans. (2001) (387)
- Patterns of viral replication correlate with outcome in simian immunodeficiency virus (SIV)-infected macaques: effect of prior immunization with a trivalent SIV vaccine in modified vaccinia virus Ankara (1996) (317)
- Role of CD8+ Lymphocytes in Control of Simian Immunodeficiency Virus Infection and Resistance to Rechallenge after Transient Early Antiretroviral Treatment (2001) (290)
- Viral dynamics of primary viremia and antiretroviral therapy in simian immunodeficiency virus infection (1997) (283)
- CD4-independent, CCR5-dependent infection of brain capillary endothelial cells by a neurovirulent simian immunodeficiency virus strain. (1997) (277)
- A B cell follicle sanctuary permits persistent productive SIV infection in elite controllers (2014) (276)
- Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth. (2016) (276)
- ALVAC-SIV-gag-pol-env-Based Vaccination and Macaque Major Histocompatibility Complex Class I (A*01) Delay Simian Immunodeficiency Virus SIVmac-Induced Immunodeficiency (2002) (271)
- The extent of early viral replication is a critical determinant of the natural history of simian immunodeficiency virus infection (1997) (249)
- TRIM5 Suppresses Cross-Species Transmission of a Primate Immunodeficiency Virus and Selects for Emergence of Resistant Variants in the New Species (2010) (248)
- Nucleotide sequence analysis of feline immunodeficiency virus: genome organization and relationship to other lentiviruses. (1989) (234)
- Mosaic genome structure of simian immunodeficiency virus from west African green monkeys. (1994) (230)
- Induction of AIDS by simian immunodeficiency virus from an African green monkey: species-specific variation in pathogenicity correlates with the extent of in vivo replication (1995) (228)
- Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts (2009) (228)
- Paucity of CD4+CCR5+ T cells is a typical feature of natural SIV hosts. (2007) (218)
- Plasma SIV RNA viral load determination by real-time quantification of product generation in reverse transcriptase-polymerase chain reaction. (1998) (213)
- Downregulation of Robust Acute Type I Interferon Responses Distinguishes Nonpathogenic Simian Immunodeficiency Virus (SIV) Infection of Natural Hosts from Pathogenic SIV Infection of Rhesus Macaques (2010) (212)
- Reduction of Simian-Human Immunodeficiency Virus 89.6P Viremia in Rhesus Monkeys by Recombinant Modified Vaccinia Virus Ankara Vaccination (2001) (197)
- Species-specific diversity among simian immunodeficiency viruses from African green monkeys (1991) (194)
- Vpx is required for dissemination and pathogenesis of SIVSM PBj: Evidence of macrophage-dependent viral amplification (1998) (187)
- Comparative Efficacy of Recombinant Modified Vaccinia Virus Ankara Expressing Simian Immunodeficiency Virus (SIV) Gag-Pol and/or Env in Macaques Challenged with Pathogenic SIV (2000) (178)
- Strong sequence conservation among horizontally transmissible, minimally pathogenic feline leukemia viruses (1988) (169)
- Molecular cloning of feline immunodeficiency virus. (1989) (168)
- Pathogenic diversity of simian immunodeficiency viruses. (1994) (167)
- Origins and evolution of AIDS viruses: estimating the time-scale. (2000) (165)
- Containment of Simian Immunodeficiency Virus Infection: Cellular Immune Responses and Protection from Rechallenge following Transient Postinoculation Antiretroviral Treatment (2000) (163)
- Highly pathogenic SHIVs and SIVs target different CD4+ T cell subsets in rhesus monkeys, explaining their divergent clinical courses. (2004) (162)
- Cloning of HTLV-4 and its relation to simian and human immunodeficiency viruses (1987) (160)
- Passive immune globulin therapy in the SIV/macaque model: early intervention can alter disease profile. (1996) (158)
- Immunization with a Modified Vaccinia Virus Expressing Simian Immunodeficiency Virus (SIV) Gag-Pol Primes for an Anamnestic Gag-Specific Cytotoxic T-Lymphocyte Response and Is Associated with Reduction of Viremia after SIV Challenge (2000) (158)
- Simian Immunodeficiency Virus SIVagm.sab Infection of Caribbean African Green Monkeys: a New Model for the Study of SIV Pathogenesis in Natural Hosts (2006) (154)
- Early short-term treatment with neutralizing human monoclonal antibodies halts SHIV infection in newborn macaques (2016) (153)
- The genome organization of STLV-3 is similar to that of the AIDS virus except for a truncated transmembrane protein (1987) (147)
- SIV adaption to human cells (1989) (143)
- Host range restricted, non-replicating vaccinia virus vectors as vaccine candidates. (1996) (141)
- Complement control proteins, CD46, CD55, and CD59, as common surface constituents of human and simian immunodeficiency viruses and possible targets for vaccine protection. (1994) (139)
- A molecularly cloned, pathogenic, neutralization-resistant simian immunodeficiency virus, SIVsmE543-3 (1997) (133)
- Wide Range of Viral Load in Healthy African Green Monkeys Naturally Infected with Simian Immunodeficiency Virus (2000) (128)
- Loss of CD103+ DCs and Mucosal IL-17+ and IL-22+ Lymphocytes is Associated with Mucosal Damage in SIV Infection (2012) (123)
- The genetic fate of molecularly cloned simian immunodeficiency virus in experimentally infected macaques. (1991) (123)
- Recombinant modified vaccinia virus Ankara-simian immunodeficiency virus gag pol elicits cytotoxic T lymphocytes in rhesus monkeys detected by a major histocompatibility complex class I/peptide tetramer. (1998) (119)
- Characterization of Novel Simian Immunodeficiency Viruses from Red-Capped Mangabeys from Nigeria (SIVrcmNG409 and -NG411) (2001) (113)
- Resting naïve CD4+ T cells are massively infected and eliminated by X4-tropic simian–human immunodeficiency viruses in macaques (2005) (110)
- Simian immunodeficiency virus infection of monkeys as a model system for the study of AIDS pathogenesis, treatment, and prevention. (2000) (110)
- A distinct African lentivirus from Sykes' monkeys (1993) (108)
- Passive Immunotherapy in Simian Immunodeficiency Virus-Infected Macaques Accelerates the Development of Neutralizing Antibodies (2004) (108)
- Simian immunodeficiency viruses from African green monkeys display unusual genetic diversity (1990) (105)
- Prevention of infection by a granulocyte-macrophage colony-stimulating factor co-expressing DNA/modified vaccinia Ankara simian immunodeficiency virus vaccine. (2011) (105)
- Characterization of a Novel Simian Immunodeficiency Virus (SIV) from L’Hoest Monkeys (Cercopithecus l’hoesti): Implications for the Origins of SIVmnd and Other Primate Lentiviruses (1999) (102)
- The host restriction factor APOBEC3G and retroviral Vif protein coevolve due to ongoing genetic conflict. (2012) (102)
- Down-regulation of CD4 by memory CD4+ T cells in vivo renders African green monkeys resistant to progressive SIVagm infection (2009) (99)
- Tissue myeloid cells in SIV-infected primates acquire viral DNA through phagocytosis of infected T cells. (2014) (95)
- Elicitation of High-Frequency Cytotoxic T-Lymphocyte Responses against both Dominant and Subdominant Simian-Human Immunodeficiency Virus Epitopes by DNA Vaccination of Rhesus Monkeys (2001) (92)
- Multiple viral determinants contribute to pathogenicity of the acutely lethal simian immunodeficiency virus SIVsmmPBj variant (1993) (90)
- Evaluation of the safety, immunogenicity, and protective efficacy of whole inactivated simian immunodeficiency virus (SIV) vaccines with conformationally and functionally intact envelope glycoproteins. (2004) (90)
- What can natural infection of African monkeys with simian immunodeficiency virus tell us about the pathogenesis of AIDS? (2004) (89)
- Identification of a new subgroup of SIVagm in tantalus monkeys. (1993) (88)
- Simian immunodeficiency virus infection of macaques: end-stage disease is characterized by widespread distribution of proviral DNA in tissues. (1991) (87)
- Antibodies to the putative SIV infection‐enhancing domain diminish beneficial effects of an SIV gp160 vaccine in rhesus macaques (1995) (86)
- SIV adaptation to human cells. (1989) (82)
- Induction of simian immunodeficiency virus (SIV)-specific CTL in rhesus macaques by vaccination with modified vaccinia virus Ankara expressing SIV transgenes: influence of pre-existing anti-vector immunity. (2001) (81)
- DNA and virus particle vaccination protects against acquisition and confers control of viremia upon heterologous simian immunodeficiency virus challenge (2013) (76)
- Comparison of Simian Immunodeficiency Virus SIVagmVer Replication and CD4+ T-Cell Dynamics in Vervet and Sabaeus African Green Monkeys (2006) (75)
- Simian immunodeficiency virus (SIV) from sun-tailed monkeys (Cercopithecus solatus): evidence for host-dependent evolution of SIV within the C. lhoesti superspecies. (1999) (73)
- Nonpathogenic simian immunodeficiency virus infections. (2012) (73)
- Cytotoxic T lymphocytes specific for the simian immunodeficiency virus (1999) (72)
- Simian immunodeficiency viruses replication dynamics in African non‐human primate hosts: common patterns and species‐specific differences (2006) (70)
- Dynamic immune responses maintain cytotoxic T lymphocyte epitope mutations in transmitted simian immunodeficiency virus variants (2005) (70)
- Phylogeny and natural history of the primate lentiviruses, SIV and HIV. (1995) (69)
- A highly divergent proviral DNA clone of SIV from a distinct species of African green monkey. (1991) (68)
- Unique Pathology in Simian Immunodeficiency Virus-Infected Rapid Progressor Macaques Is Consistent with a Pathogenesis Distinct from That of Classical AIDS (2007) (68)
- Antibody-dependent enhancement of simian immunodeficiency virus (SIV) infection in vitro by plasma from SIV-infected rhesus macaques (1990) (67)
- The Canarypox Virus Vector ALVAC Induces Distinct Cytokine Responses Compared to the Vaccinia Virus-Based Vectors MVA and NYVAC in Rhesus Monkeys (2013) (66)
- SIVmac239 MVA vaccine with and without a DNA prime, similar prevention of infection by a repeated dose SIVsmE660 challenge despite different immune responses. (2012) (65)
- Recombinant Modified Vaccinia Virus Ankara Expressing the Surface gp120 of Simian Immunodeficiency Virus (SIV) Primes for a Rapid Neutralizing Antibody Response to SIV Infection in Macaques (2000) (64)
- CD4-Like Immunological Function by CD4− T Cells in Multiple Natural Hosts of Simian Immunodeficiency Virus (2011) (61)
- No Evidence for Consistent Virus-Specific Immunity in Simian Immunodeficiency Virus-Exposed, Uninfected Rhesus Monkeys (2007) (60)
- Plateau Levels of Viremia Correlate with the Degree of CD4+-T-Cell Loss in Simian Immunodeficiency Virus SIVagm-Infected Pigtailed Macaques: Variable Pathogenicity of Natural SIVagm Isolates (2005) (58)
- Stably Expressed APOBEC3F Has Negligible Antiviral Activity (2010) (57)
- Characterization and Comparison of Recombinant Simian Immunodeficiency Virus from Drill (Mandrillus leucophaeus) and Mandrill (Mandrillus sphinx) Isolates (2003) (57)
- The role of nonhuman primates in the development of an AIDS vaccine. (1999) (56)
- Loss of Naïve Cells Accompanies Memory CD4+ T-Cell Depletion during Long-Term Progression to AIDS in Simian Immunodeficiency Virus-Infected Macaques (2006) (55)
- Tissue-resident macrophages can contain replication-competent virus in antiretroviral-naive, SIV-infected Asian macaques. (2017) (55)
- Rapid and Irreversible CD4+ T-Cell Depletion Induced by the Highly Pathogenic Simian/Human Immunodeficiency Virus SHIVDH12R Is Systemic and Synchronous (2002) (54)
- Selective infection of human CD4+ cells by simian immunodeficiency virus: productive infection associated with envelope glycoprotein-induced fusion. (1989) (54)
- The emergence and characterization of macrophage‐tropic SIV/HIV chimeric viruses (SHIVs) present in CD4+ T cell‐depleted rhesus monkeys (2003) (53)
- Intrinsic Susceptibility of Rhesus Macaque Peripheral CD4+ T Cells to Simian Immunodeficiency Virus In Vitro Is Predictive of In Vivo Viral Replication (2000) (52)
- SIV infection of macaques as a model for AIDS pathogenesis. (1992) (51)
- Mechanisms underlying γδ T-cell subset perturbations in SIV-infected Asian rhesus macaques. (2010) (50)
- Simian immunodeficiency virus of African green monkeys is apathogenic in the newborn natural host. (1998) (50)
- Molecular Cloning of SIV From Sooty Mangabey Monkeys (1989) (50)
- Nucleotide sequence analysis of puma lentivirus (PLV-14): genomic organization and relationship to other lentiviruses. (1994) (49)
- Patterns of Genomic Sequence Diversity among Their Simian Immunodeficiency Viruses Suggest that L'Hoest Monkeys (Cercopithecus lhoesti) Are a Natural Lentivirus Reservoir (2000) (48)
- SIV from stump-tailed macaques: molecular characterization of a highly transmissible primate lentivirus. (1992) (48)
- Decreased Levels of Recent Thymic Emigrants in Peripheral Blood of Simian Immunodeficiency Virus-Infected Macaques Correlate with Alterations within the Thymus (2002) (48)
- Modeling a safer smallpox vaccination regimen, for human immunodeficiency virus type 1-infected patients, in immunocompromised macaques. (2003) (46)
- Prolonged clinical latency and survival of macaques given a whole inactivated simian immunodeficiency virus vaccine. (1994) (46)
- Inhibition of Adaptive Immune Responses Leads to a Fatal Clinical Outcome in SIV-Infected Pigtailed Macaques but Not Vervet African Green Monkeys (2009) (45)
- Cloning and sequences of primate CD4 molecules: Diversity of the cellular receptor for simian immunodeficiency virus/human immunodeficiency virus (1992) (45)
- Simian Immunodeficiency Virus (SIV) Envelope-Specific Fabs with High-Level Homologous Neutralizing Activity: Recovery from a Long-Term-Nonprogressor SIV-Infected Macaque (1998) (45)
- Immune Failure in the Absence of Profound CD4+ T-Lymphocyte Depletion in Simian Immunodeficiency Virus-Infected Rapid Progressor Macaques (2004) (45)
- TRIM5α Does Not Affect Simian Immunodeficiency Virus SIVmac251 Replication in Vaccinated or Unvaccinated Indian Rhesus Macaques following Intrarectal Challenge Exposure (2011) (45)
- Simian Immunodeficiency Virus (SIV) from Sun-Tailed Monkeys (Cercopithecus solatus): Evidence for Host-Dependent Evolution of SIV within the C. lhoestiSuperspecies (1999) (45)
- Increased Loss of CCR5+ CD45RA− CD4+ T Cells in CD8+ Lymphocyte-Depleted Simian Immunodeficiency Virus-Infected Rhesus Monkeys (2008) (42)
- Simian Immunodeficiency Virus (SIV)-Specific CD8+ T-Cell Responses in Vervet African Green Monkeys Chronically Infected with SIVagm (2008) (42)
- Vpr of simian immunodeficiency virus of African green monkeys is required for replication in macaque macrophages and lymphocytes (1997) (42)
- TRIM5α-Mediated Ubiquitin Chain Conjugation Is Required for Inhibition of HIV-1 Reverse Transcription and Capsid Destabilization (2015) (42)
- Abdominocentesis in cattle: technique and criteria for diagnosis of peritonitis. (1985) (41)
- Vpx is Critical for SIVmne infection of pigtail macaques (2012) (40)
- Simian Immunodeficiency Virus SIVagm Efficiently Utilizes Non-CCR5 Entry Pathways in African Green Monkey Lymphocytes: Potential Role for GPR15 and CXCR6 as Viral Coreceptors (2015) (40)
- Molecular clones of SIVsm and SIVagm: experimental infection of macaques and African green monkeys. (1990) (40)
- TRIM5 alpha Drives SIVsmm Evolution in Rhesus Macaques (2013) (40)
- Immunization with whole inactivated vaccine protects from infection by SIV grown in human but not macaque cells (1994) (39)
- Coexpression of the simian immunodeficiency virus Env and Rev proteins by a recombinant human adenovirus host range mutant (1992) (39)
- Extensive envelope heterogeneity of simian immunodeficiency virus in tissues from infected macaques (1994) (39)
- Unique Pattern of Convergent Envelope Evolution in Simian Immunodeficiency Virus-Infected Rapid Progressor Macaques: Association with CD4-Independent Usage of CCR5 (2003) (38)
- A retrospective study of canine hemangiosarcoma and its association with acanthocytosis. (1981) (37)
- CD8+ and CD20+ Lymphocytes Cooperate To Control Acute Simian Immunodeficiency Virus/Human Immunodeficiency Virus Chimeric Virus Infections in Rhesus Monkeys: Modulation by Major Histocompatibility Complex Genotype (2005) (37)
- Cross-reactivity to human T-lymphotropic virus type III/lymphadenopathy-associated virus and molecular cloning of simian T-cell lymphotropic virus type III from African green monkeys. (1986) (37)
- Mucosa-Associated Invariant T Cells Are Systemically Depleted in Simian Immunodeficiency Virus-Infected Rhesus Macaques (2016) (37)
- Animal models for acquired immunodeficiency syndrome. (1992) (36)
- Pattern of SIVagm infection in patas monkeys suggests that host adaptation to simian immunodeficiency virus infection may result in resistance to infection and virus extinction. (2010) (36)
- In vitro characterization of primary SIVsmm isolates belonging to different lineages. In vitro growth on rhesus macaque cells is not predictive for in vivo replication in rhesus macaques. (2007) (36)
- Sequential Evolution and Escape from Neutralization of Simian Immunodeficiency Virus SIVsmE660 Clones in Rhesus Macaques (2012) (35)
- TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation (2019) (35)
- Association of Progressive CD4+ T Cell Decline in SIV Infection with the Induction of Autoreactive Antibodies (2009) (34)
- Infectious Molecular Clones from a Simian Immunodeficiency Virus-Infected Rapid-Progressor (RP) Macaque: Evidence of Differential Selection of RP-Specific Envelope Mutations In Vitro and In Vivo (2006) (33)
- Spontaneous substitutions in the vicinity of the V3 analog affect cell tropism and pathogenicity of simian immunodeficiency virus (1994) (33)
- Immunodeficiency in the Absence of High Viral Load in Pig-Tailed Macaques Infected with Simian Immunodeficiency Virus SIVsun or SIVlhoest (2005) (33)
- Macrophages in Progressive Human Immunodeficiency Virus/Simian Immunodeficiency Virus Infections (2016) (33)
- Suppression of adaptive immune responses during primary SIV infection of sabaeus African green monkeys delays partial containment of viremia but does not induce disease. (2010) (31)
- Treatment with IL-7 Prevents the Decline of Circulating CD4+ T Cells during the Acute Phase of SIV Infection in Rhesus Macaques (2012) (31)
- Control of Heterologous Simian Immunodeficiency Virus SIVsmE660 Infection by DNA and Protein Coimmunization Regimens Combined with Different Toll-Like-Receptor-4-Based Adjuvants in Macaques (2018) (30)
- Protection of Macaques with Diverse MHC Genotypes against a Heterologous SIV by Vaccination with a Deglycosylated Live-Attenuated SIV (2010) (28)
- Genetic variation of simian immunodeficiency viruses in nonhuman primates. (1992) (28)
- Laser Capture Microdissection Assessment of Virus Compartmentalization in the Central Nervous Systems of Macaques Infected with Neurovirulent Simian Immunodeficiency Virus (2013) (28)
- Contributions of CD4+, CD8+, and CD4+CD8+ T cells to skewing within the peripheral T cell receptor beta chain repertoire of healthy macaques. (1999) (28)
- Simian immunodeficiency viruses from multiple lineages infect human macrophages: implications for cross-species transmission. (2003) (25)
- Peritoneal fluid analysis in the diagnosis of abdominal disorders in cattle: a retrospective study. (1982) (25)
- Conformational Epitope Consisting of the V3 and V4 Loops as a Target for Potent and Broad Neutralization of Simian Immunodeficiency Viruses (2013) (25)
- Rapid SIV Env-specific mucosal and serum antibody induction augments cellular immunity in protecting immunized, elite-controller macaques against high dose heterologous SIV challenge. (2011) (24)
- Prior Vaccination Increases the Epitopic Breadth of the Cytotoxic T-Lymphocyte Response That Evolves in Rhesus Monkeys following a Simian-Human Immunodeficiency Virus Infection (2002) (23)
- Comparative Population Genomics Analysis of the Mammalian Fungal Pathogen Pneumocystis (2018) (23)
- Diversity and Evolution of Primate Lentiviruses (2000) (22)
- Characterization of red-capped mangabey tetherin: implication for the co-evolution of primates and their lentiviruses (2014) (21)
- Owner response to amputation of a pet's leg. (1979) (21)
- Improved Survival in Rhesus Macaques Immunized with Modified Vaccinia Virus Ankara Recombinants Expressing Simian Immunodeficiency Virus Envelope Correlates with Reduction in Memory CD4+ T-Cell Loss and Higher Titers of Neutralizing Antibody (2009) (20)
- Viral Genetic Evolution in Macaques Infected with Molecularly Cloned Simian Immunodeficiency Virus Correlates with the Extent of Persistent Viremia (1998) (20)
- AIDS Vaccine Development (1998) (20)
- Pathogenesis of AIDS: the non-human primate model. (1991) (19)
- High Frequency of Virus-Specific CD8+ T Cells in the Central Nervous System of Macaques Chronically Infected with Simian Immunodeficiency Virus SIVmac251 (2003) (19)
- Budding of a Retrovirus: Some Assemblies Required (2020) (19)
- Structure, origin, and transforming activity of feline leukemia virus-myc recombinant provirus FTT (1989) (19)
- Characterization of Simian Immunodeficiency Virus (SIV) That Induces SIV Encephalitis in Rhesus Macaques with High Frequency: Role of TRIM5 and Major Histocompatibility Complex Genotypes and Early Entry to the Brain (2014) (18)
- Development of Neurological Disease Is Associated with Increased Immune Activation in Simian Immunodeficiency Virus-Infected Macaques (2012) (18)
- Receptor function of CD4 structures from African green monkey and pig-tail macaque for simian immunodeficiency virus, SIVsm, SIVagm, and human immunodeficiency virus type-1. (1995) (18)
- Viral genetic determinants in SIVsmmPBj pathogenesis (1994) (18)
- The diagnostic significance of a positive direct antiglobulin test in anemic cats. (1984) (18)
- A SIV molecular clone that targets the CNS and induces neuroAIDS in rhesus macaques (2017) (17)
- The ITAM in Nef Influences Acute Pathogenesis of AIDS-Inducing Simian Immunodeficiency Viruses SIVsm and SIVagm without Altering Kinetics or Extent of Viremia (2002) (17)
- Suppurative cholangitis in cats. (1983) (17)
- The locus encoding an oligomorphic family of MHC-A alleles (Mane-A*06/Mamu-A*05) is present at high frequency in several macaque species (2007) (17)
- Detection of SIV antigens by HIV-1 antigen capture immunoassays. (1990) (17)
- Genetic Diversity Among Simian Immunodeficiency Virus Isolates From African Green Monkeys (1989) (17)
- Molecular diversity of SIVsmm/PBj and a cognate variant, SIVsmm/PGg. (1991) (17)
- Glucocorticoid treatment at moderate doses of SIVmac251-infected rhesus macaques decreases the frequency of circulating CD14+CD16++ monocytes but does not alter the tissue virus reservoir. (2015) (16)
- Molecular characterization of SIV in tissues from experimentally infected macaques. (1990) (15)
- Characterization of group specific antibodies in primates: studies with SIV envelope in macaques. (1992) (15)
- A Rapid Progressor-Specific Variant Clone of Simian Immunodeficiency Virus Replicates Efficiently In Vivo Only in the Absence of Immune Reponses (2007) (15)
- TRIM5α Restriction Affects Clinical Outcome and Disease Progression in Simian Immunodeficiency Virus-Infected Rhesus Macaques (2014) (14)
- Hereditary anomaly of neutrophil granulation in Birman cats. (1984) (14)
- Coevolutionary dynamics between tribe Cercopithecini tetherins and their lentiviruses (2015) (14)
- Serum iron, total iron binding capacity, plasma copper and hemoglobin types in anemic and poikilocytic calves. (1985) (13)
- Genomic insights into the host specific adaptation of the Pneumocystis genus (2021) (11)
- Simian Immunodeficiency Virus-Infected Memory CD4+ T Cells Infiltrate to the Site of Infected Macrophages in the Neuroparenchyma of a Chronic Macaque Model of Neurological Complications of AIDS (2020) (11)
- Genetic variation of the SIVagm transmembrane glycoprotein in naturally and experimentally infected primates (1993) (11)
- The simian immunodeficiency virus (SIV) rev gene regulates env expression. (1990) (11)
- Characterization of a Macaque Recombinant Monoclonal Antibody That Binds to a CD4-Induced Epitope and Neutralizes Simian Immunodeficiency Virus (2000) (11)
- SIV-specific CD8+ T cells are clonotypically distinct across lymphoid and mucosal tissues. (2020) (10)
- Evolution of the fittest ends in tragedy (1999) (10)
- Persistent transcription of a nonintegrating mutant of simian immunodeficiency virus in rhesus macrophages. (2008) (10)
- Peritoneal fluid analysis in the diagnosis of abdominal disorders in cattle: a retrospective study. (1983) (9)
- Coexpression of biologically active simian immunodeficiency virus (SIV) Rev and Env in an SV40 system: the SIV rev gene regulates env expression. (1990) (9)
- Homeostatic Cytokines Induce CD4 Downregulation in African Green Monkeys Independently of Antigen Exposure To Generate Simian Immunodeficiency Virus-Resistant CD8αα T Cells (2014) (8)
- Epigenetic silencing of CD4 expression in nonpathogenic SIV infection in African green monkeys (2020) (8)
- Characterization of a monoclonal anti-capsid antibody that cross-reacts with three major primate lentivirus lineages. (2012) (8)
- Enhanced antagonism of BST-2 by a neurovirulent SIV envelope. (2016) (8)
- Neuroinflammatory Changes in Relation to Cerebrospinal Fluid Viral Load in Simian Immunodeficiency Virus Encephalitis (2019) (8)
- Antibody-dependent enhancement of SIV infection: further characterization and cross reactivity between macaque and sooty mangabey isolates. (1990) (8)
- Rapid disease progression to AIDS due to Simian immunodeficiency virus infection of macaques: host and viral factors. (2008) (8)
- Truncating the gp41 Cytoplasmic Tail of Simian Immunodeficiency Virus Decreases Sensitivity to Neutralizing Antibodies without Increasing the Envelope Content of Virions (2017) (8)
- Adaptive evolution of simian immunodeficiency viruses isolated from 2 conventional-progressor macaques with encephalitis. (2008) (7)
- CD 4-Like Immunological Function by CD 4 T Cells in Multiple Natural Hosts of Simian Immunodeficiency Virus † (2011) (7)
- Rapid screening for simian immunodeficiency virus variants using single-strand conformation polymorphism of PCR-amplified DNA fragments. (1993) (7)
- Diversity and Complexity of the Large Surface Protein Family in the Compacted Genomes of Multiple Pneumocystis Species (2020) (7)
- Cytotoxic T Cell Functions Accumulate When CD4 Is Downregulated by CD4+ T Cells in African Green Monkeys (2017) (7)
- Biologic Studies of Chimeras of Highly and Moderately Virulent Molecular Clones of Simian Immunodeficiency Virus SIVsmPBj Suggest a Critical Role for Envelope in Acute AIDS Virus Pathogenesis (2001) (7)
- Infection with a molecularly cloned SIVsm virus elicits high titer homologous neutralizing antibodies with heterologous neutralizing activity (2005) (7)
- Molecular characterization of simian lentiviruses from east African green monkeys. (1990) (7)
- Pattern of SIVagm Infection in Patas Monkeys Suggests that Host Adaptation to SIV Infection May Result in Resistance to Infection and Virus Extinction (2010) (6)
- Replication of simian immunodeficiency virus (SIV) in ex vivo lymph nodes as a means to assess susceptibility of macaques in vivo. (2000) (6)
- From Capsids to Complexes: Expanding the Role of TRIM5α in the Restriction of Divergent RNA Viruses and Elements (2021) (6)
- Blocking and tackling HIV (2009) (6)
- Distal Leucines Are Key Functional Determinants of Alix-Binding Simian Immunodeficiency Virus SIVsmE543 and SIVmac239 Type 3 L Domains (2011) (6)
- Potential Mechanism for HIV-Associated Depression: Upregulation of Serotonin Transporters in SIV-Infected Macaques Detected by 11C-DASB PET (2019) (6)
- TRIM5α Resistance Escape Mutations in the Capsid Are Transferable between Simian Immunodeficiency Virus Strains (2016) (6)
- CD4 receptor diversity represents an ancient protection mechanism against primate lentiviruses (2021) (4)
- Simian Immunodeficiency Virus (SIV)-specific CD8+ T cell responses in 1 (2008) (3)
- SIV infection duration largely determines broadening of neutralizing antibody response in macaques. (2020) (3)
- 2019-0611 TRIM 5 alpha Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation (2019) (3)
- A schirrhous anaplastic carcinoma in two dogs resembling mesothelioma. (1981) (3)
- Control of Heterologous SIVsmE660 infection by DNA and Protein Co-immunization Regimens Combined with Different Toll-like Receptor-4 (TLR-4) Based Adjuvants in Macaques (2018) (2)
- Down-modulation of primate lentiviral receptors by Nef proteins of simian immunodeficiency virus (SIV) of chimpanzees (SIVcpz) and related SIVs: implication for the evolutionary event at the emergence of SIVcpz. (2015) (2)
- A Potent Anti-Simian Immunodeficiency Virus Neutralizing Antibody Induction Associated with a Germ Line Immunoglobulin Gene Polymorphism in Rhesus Macaques (2021) (2)
- Interleukin-2 Therapy Induces CD4 Downregulation, Which Decreases Circulating CD4 T Cell Counts, in African Green Monkeys (2016) (2)
- Multiple cytopenias associated with monocytic proliferation in a dog. (1984) (2)
- A macaque adherent cell line that expresses human CD4 is susceptible to SIV: utility for assessing neutralizing antibody. (1995) (2)
- Track A Basic Science (2012) (1)
- Epigenetic Reprogramming Leads to Downregulation of CD4 and Functional Changes in African Green Monkey Memory CD4+ T Cells (2022) (1)
- Vpx is Critical for SIVmne infection of pigtail macaques (2012) (1)
- Diversity and complexity of the large surface protein family in the compacted genomes of various Pneumocystis species (2019) (1)
- Erratum: Rose et al. When in Need of an ESCRT: The Nature of Virus Assembly Sites Suggests Mechanistic Parallels between Nuclear Virus Egress and Retroviral Budding. Viruses 2021, 13, 1138 (2021) (1)
- AIDS response (1991) (0)
- Distal Leucines Are Key Functional Determinants of Alix-Binding Simian Immunodeficiency Virus SIV smE543 and SIV mac239 Type 3 L Domains (cid:1) (2011) (0)
- Genomic insights into the host specific adaptation of the Pneumocystis genus (2021) (0)
- Lymphosarcoma with hypercalcemia and osteolysis in a dog. (1983) (0)
- Title Coevolutionary dynamics between tribe Cercopithecinitetherins and their lentiviruses (2016) (0)
- Cell-associated provirus size decreases in the xenografted CD4 T cells from chronically infected natural host in a novel simianized mice model (2019) (0)
- In Memory of Jonathan Sawyer Allan, MSc, DVM (2010) (0)
- TRIM5 (cid:2) Restriction Affects Clinical Outcome and Disease Progression in Simian Immunodeficiency Virus-Infected Rhesus Macaques (2015) (0)
- Genomic insights into the host specific adaptation of the Pneumocystis genus and emergence of the human pathogen Pneumocystis jirovecii (2020) (0)
- This information is current as Cells in African Green Monkeys T + When CD 4 Is Downregulated by CD 4 Cytotoxic T Cell Functions Accumulate (2017) (0)
- Molecular cloning of feline immunodeficiency virus (feline immunodeficiency virus proviral clone/cross-hybridization/animal model/acquired immunodeficiency syndrome) (2016) (0)
- Unique regulation of the DNA methylation machinery in natural hosts contributes to CD4 gene repression and SIV disease non-progression (2020) (0)
- Nonhuman Primate Models for AIDS (2008) (0)
- Molecular cloning and biological activity of human t cell lymphotropic virus type 4 (1987) (0)
- Variability in intrinsic susceptibility as a correlate of disease progression in SIV-infected macaques (2000) (0)
- REPORTE CORTO/SHORT REPORT - PASSIVE IMMUNE GLOBULIN THERAPY AND ITS POTENTIAL FOR REDUCING VIRAL BURDEN (1995) (0)
- Genome organization and sequence homology between human immunodeficiency virus and type 3 simian t lymphotrophic virus (1987) (0)
- Characterization Of Group-specific Antibodies Generated By Lentivirus Infection Or Subunit Immunization In Primates (1993) (0)
- Mechanisms underlying (cid:1)(cid:2) T-cell subset perturbations in SIV-infected Asian rhesus macaques (2010) (0)
- Phylogenetic Associations ofHumanandSimian T-Cell Leukemia/Lymphotropic Virus TypeIStrains: Evidence forInterspecies Transmission (1994) (0)
- Truncating the Gp41 Cytoplasmic Tail of SIV Decreases Sensitivity to 1 Neutralizing Antibodies without Increasing Envelope Content of 2 Virions 3 (2017) (0)
- Correction of a carboxyl terminal simian immunodeficiency virus Nef frameshift mutation restores virus replication in macaques. (2010) (0)
- Increased Loss of CCR5 (cid:1) CD45RA (cid:2) CD4 (cid:1) T Cells in CD8 (cid:1) Lymphocyte-Depleted Simian Immunodeficiency Virus-Infected Rhesus Monkeys (cid:1) (2008) (0)
- A SIV molecular clone that induces neuroAIDS in infected rhesus macaques (2015) (0)
- T cells is a typical feature of natural SIV hosts + CCR5 + Paucity of CD4 (2011) (0)
- Enhancement ofSimianImmunodeficiency Virus(SIV) Infection InVitro byPlasmafromSIV-Infected Rhesus Macaques (1990) (0)
- Immunodeficiency Virus SIVmac 251 Macaques Chronically Infected with Simian Cells in the Central Nervous System of T + High Frequency of Virus-Specific CD 8 (2003) (0)
- E112 Comparison of systemic and mucosal responses after DNA and protein co-immunization (2013) (0)
- Mutation in the Disordered Linker Region of Capsid Disrupts Viral Kinetics of a Neuropathogenic SIV in Rhesus Macaques (2022) (0)
- Fifth International Conference on AIDS : the Scientific and Social Challenge; specialty session transcript; animal models, part 1 (1989) (0)
- Edinburgh Research Explorer Simian immunodeficiency virus (SIV) from sun-tailed monkeys (Cercopithecus solatus) (1999) (0)
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