Vera Maria Rogiers

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Vera Maria Rogiers

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#2928

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#42

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#46

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Vera Maria Rogiers

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#9627

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Vera Maria Rogiers

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#11819

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Medical
Mathematics
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Vera Maria Rogiers's Degrees

PhD Pharmaceutical Sciences Vrije Universiteit Brussel
Masters Pharmaceutical Sciences Vrije Universiteit Brussel

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Vera Maria Rogiers's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME (2013) (1068)
Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010 (2011) (536)
EEMCO Guidance for the Assessment of Transepidermal Water Loss in Cosmetic Sciences (2001) (478)
Sustained serine proteases activity by prolonged increase in pH leads to degradation of lipid processing enzymes and profound alterations of barrier function and stratum corneum integrity. (2005) (284)
Molecular mechanisms underlying the dedifferentiation process of isolated hepatocytes and their cultures. (2006) (275)
In Vitro Differentiation of Embryonic and Adult Stem Cells into Hepatocytes: State of the Art (2009) (262)
Trichostatin A-like hydroxamate histone deacetylase inhibitors as therapeutic agents: toxicological point of view. (2004) (249)
Connexin-related signaling in cell death: to live or let die? (2009) (241)
Connexins and their channels in cell growth and cell death. (2006) (231)
Keratin 19: a key role player in the invasion of human hepatocellular carcinomas (2013) (216)
Selective inhibition of Cx43 hemichannels by Gap19 and its impact on myocardial ischemia/reperfusion injury (2012) (207)
A histone deacetylase inhibitor, trichostatin A, suppresses myofibroblastic differentiation of rat hepatic stellate cells in primary culture (1999) (190)
Ca(2+) regulation of connexin 43 hemichannels in C6 glioma and glial cells. (2009) (182)
Paracrine signaling through plasma membrane hemichannels. (2013) (180)
Connexin 43 hemichannels contribute to the propagation of apoptotic cell death in a rat C6 glioma cell model (2009) (169)
Transforming growth factor-β gene expression in normal and fibrotic rat liver (1997) (168)
A Review of the Implementation of the Embryonic Stem Cell Test (EST) (2009) (165)
Glutathione Levels Discriminate between Oxidative Stress and Transforming Growth Factor-β Signaling in Activated Rat Hepatic Stellate Cells* (1999) (154)
Sequential exposure to cytokines reflecting embryogenesis: the key for in vitro differentiation of adult bone marrow stem cells into functional hepatocyte-like cells. (2006) (136)
Toxicogenomics directory of chemically exposed human hepatocytes (2014) (135)
EEMCO Guidance for the in vivo Assessment of Skin Greasiness (2000) (134)
Validation of the VapoMeter, a closed unventilated chamber system to assess transepidermal water loss vs. the open chamber Tewameter® (2005) (130)
Connexin Channels Provide a Target to Manipulate Brain Endothelial Calcium Dynamics and Blood—Brain Barrier Permeability (2011) (127)
Insulinlike growth factor—ii/mannose 6‐phosphate receptor is expressed on ccl4‐exposed rat fat‐storing cells and facilitates activation of latent transforming growth factor‐β in cocultures with sinusoidal endothelial cells (1995) (123)
Pannexin channels in ATP release and beyond: an unexpected rendezvous at the endoplasmic reticulum. (2011) (113)
Development of an adverse outcome pathway from drug-mediated bile salt export pump inhibition to cholestatic liver injury. (2013) (113)
Primary hepatocyte cultures for pharmaco-toxicological studies: at the busy crossroad of various anti-dedifferentiation strategies (2013) (103)
Chronic administration of valproic acid inhibits activation of mouse hepatic stellate cells in vitro and in vivo (2010) (103)
COVID-19 and drug-induced liver injury: a problem of plenty or a petty point? (2020) (102)
Non-channel functions of connexins in cell growth and cell death. (2012) (98)
Involvement of Cell Junctions in Hepatocyte Culture Functionality (2006) (97)
A Keratinocyte’s Course of Life (2006) (95)
Biology and pathobiology of gap junctional channels in hepatocytes (2008) (91)
Chromatin remodeling agent trichostatin A: a key-factor in the hepatic differentiation of human mesenchymal stem cells derived of adult bone marrow (2007) (91)
Rat hepatocyte cultures and co-cultures in biotransformation studies of xenobiotics. (1993) (88)
Isolation of rat hepatocytes. (2006) (87)
Localization and cellular sources of activins in normal and fibrotic rat liver (1997) (86)
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME (2013) (84)
Phase I and phase II xenobiotic biotransformation in cultures and co-cultures of adult rat hepatocytes. (1990) (83)
Strategies for immortalization of primary hepatocytes. (2014) (83)
Assessment of stability, toxicity and immunogenicity of new polymeric nanoreactors for use in enzyme replacement therapy of MNGIE. (2009) (80)
Connexins: sensors and regulators of cell cycling. (2011) (79)
Pancreatic hormone receptors on islet cells. (1985) (78)
Overview of skin whitening agents with an insight into the illegal cosmetic market in Europe (2016) (76)
Microrelief of the skin using a light transmission method (2000) (72)
Anti-NASH Drug Development Hitches a Lift on PPAR Agonism (2019) (69)
Transforming growth factor-beta gene expression in normal and fibrotic rat liver. (1997) (68)
The 3T3 neutral red uptake phototoxicity test: practical experience and implications for phototoxicity testing--the report of an ECVAM-EFPIA workshop. (2012) (67)
Role of epigenetics in liver-specific gene transcription, hepatocyte differentiation and stem cell reprogrammation. (2009) (67)
Simple and quick method for whole-liver decellularization: a novel in vitro three-dimensional bioengineering tool? (2011) (66)
The Practical Applicability of Hepatocyte Cultures in Routine Testing (1994) (66)
Calcium and connexin-based intercellular communication, a deadly catch? (2011) (66)
Trichostatin A induces differential cell cycle arrests but does not induce apoptosis in primary cultures of mitogen-stimulated rat hepatocytes. (2003) (64)
Human health safety evaluation of cosmetics in the EU: a legally imposed challenge to science. (2010) (64)
Gap junctional intercellular communication as a target for liver toxicity and carcinogenicity (2009) (62)
PPARbeta regulates vitamin A metabolism-related gene expression in hepatic stellate cells undergoing activation. (2003) (62)
Successful isolation of liver progenitor cells by aldehyde dehydrogenase activity in naïve mice (2012) (61)
The carcinoGENOMICS project: critical selection of model compounds for the development of omics-based in vitro carcinogenicity screening assays. (2008) (61)
Trichostatin a enhances gap junctional intercellular communication in primary cultures of adult rat hepatocytes. (2006) (60)
Prolonged gene silencing in hepatoma cells and primary hepatocytes after small interfering RNA delivery with biodegradable poly(β‐amino esters) (2008) (60)
Differential Effects of Histone Deacetylase Inhibitors in Tumor and Normal Cells—What Is the Toxicological Relevance? (2005) (60)
The pharmaceutical potential of histone deacetylase inhibitors. (2007) (58)
Differentiation-associated expression of ceramidase isoforms in cultured keratinocytes and epidermis Published, JLR Papers in Press, February 13, 2006. (2006) (57)
Skin condition associated with intensive use of alcoholic gels for hand disinfection: a combination of biophysical and sensorial data (2006) (57)
Regulation of connexin‐ and pannexin‐based channels by post‐translational modifications (2013) (57)
Effect of oral intake of choline-stabilized orthosilicic acid on skin, nails and hair in women with photodamaged skin (2006) (56)
Hepatic differentiation of mesenchymal stem cells: in vitro strategies. (2011) (56)
Effect of the histone deacetylase inhibitor trichostatin A on spontaneous apoptosis in various types of adult rat hepatocyte cultures. (2004) (53)
Can in vitro mammalian cell genotoxicity test results be used to complement positive results in the Ames test and help predict carcinogenic or in vivo genotoxic activity? I. Reports of individual databases presented at an EURL ECVAM Workshop. (2014) (52)
Maintenance and induction in co-cultured rat hepatocytes of components of the cytochrome P450-mediated mono-oxygenase. (1993) (52)
The use of Long-term Hepatocyte Cultures for Detecting Induction of Drug Metabolising Enzymes: The Current Status (1999) (52)
Identification of connective tissue gene transcripts in freshly isolated parenchymal, endothelial, Kupffer and fat-storing cells by northern hybridization analysis. (1993) (51)
Mesoderm-derived stem cells: the link between the transcriptome and their differentiation potential. (2012) (51)
Transfer of IP3 through gap junctions is critical, but not sufficient, for the spread of apoptosis (2011) (51)
Major phase I biotransformation pathways of Trichostatin a in rat hepatocytes and in rat and human liver microsomes. (2002) (50)
Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models. (2013) (49)
Effects of epidermal growth factor on CYP inducibility by xenobiotics, DNA replication, and caspase activations in collagen I gel sandwich cultures of rat hepatocytes. (2001) (49)
Repair of acetone‐ and sodium lauryl sulphate‐damaged human skin barrier function using topically applied emulsions containing barrier lipids (2002) (49)
Hepatocyte cultures in drug metabolism and toxicological research and testing. (2006) (49)
Trichostatin A, a critical factor in maintaining the functional differentiation of primary cultured rat hepatocytes. (2007) (49)
Human skin-derived stem cells as a novel cell source for in vitro hepatotoxicity screening of pharmaceuticals. (2015) (48)
Abnormal Fatty Acid Turnover in the Phospholipids of the Red Blood Cell Membranes of Cystic Fibrosis Patients (in Vitro Study) (1984) (48)
Toxicological and metabolic considerations for histone deacetylase inhibitors (2013) (48)
Characterization of suspected illegal skin whitening cosmetics. (2014) (47)
Changes in expression of mRNA coding for glutathione S-transferase subunits 1-2 and 7 in cultured rat hepatocytes. (1990) (47)
Epigenetic regulation of gap junctional intercellular communication: more than a way to keep cells quiet? (2009) (47)
Connexin and pannexin (hemi)channels in the liver (2013) (45)
Toxicogenomics-based prediction of acetaminophen-induced liver injury using human hepatic cell systems. (2016) (45)
Safety evaluation of cosmetics in the EU. Reality and challenges for the toxicologist. (2004) (44)
Inhibition of gluconeogenesis by sodium valproate and its metabolites in isolated rat hepatocytes. (1985) (44)
Beneficial effects of a skin tolerance‐tested moisturizing cream on the barrier function in experimentally‐elicited irritant and allergic contact dermatitis (2001) (44)
"The SCCS note of Guidance for the testing of cosmetic ingredients and their safety evaluation – 10th Revision"SCCS/1602/18 - Final version (2018) (43)
Long chain nonesterified fatty acid patterns in plasma of healthy children and young adults in relation to age and sex. (1981) (42)
Screening of repeated dose toxicity data present in SCC(NF)P/SCCS safety evaluations of cosmetic ingredients (2012) (42)
Drug-induced liver injury: mechanisms, types and biomarkers. (2013) (41)
Immortalized Human Hepatic Cell Lines for In Vitro Testing and Research Purposes. (2015) (40)
Connexin43 signaling contributes to spontaneous apoptosis in cultures of primary hepatocytes. (2012) (40)
Development and validation of a fast chromatographic method for screening and quantification of legal and illegal skin whitening agents. (2013) (40)
Assaying Cellular Viability Using the Neutral Red Uptake Assay. (2017) (40)
Effect of oral intake of choline-stabilized orthosilicic acid on skin, nails and hair in women with photodamaged skin (2006) (39)
LONG CHAIN NON-ESTERIFIED FATTY ACID PATTERN IN PLASMA OF CYSTIC FIBROSIS PATIENTS AND THEIR PARENTS (1980) (39)
Hormonal regulation of microsomal flavin-containing monooxygenase activity by sex steroids and growth hormone in co-cultured adult male rat hepatocytes. (1998) (39)
Printed paper and board food contact materials as a potential source of food contamination. (2016) (37)
Altered phospholipid composition and changed fatty acid pattern of the various phospholipid fractions of red cell membranes of cystic fibrosis children with pancreatic insufficiency. (1980) (37)
Standardized conditions needed for skin surface hydration measurements (1990) (37)
Inhibition of gap junctional intercellular communication by toxic metals. (2010) (36)
Human‐based systems: Mechanistic NASH modelling just around the corner? (2018) (35)
Effects of the anticonvulsant, valproate, on the expression of components of the cytochrome-P-450-mediated monooxygenase system and glutathione S-transferases. (1995) (35)
Omics-based responses induced by bosentan in human hepatoma HepaRG cell cultures (2018) (35)
Critical evaluation of 7-ethoxycoumarin O-deethylase activity measurement in intact isolated rat hepatocytes. (1986) (35)
Claim substantiation and efficiency of hydrating body lotions and protective creams (2000) (35)
Hormonal regulation of glutathione S-transferase expression in co-cultured adult rat hepatocytes. (2000) (34)
Workshop on acceleration of the validation and regulatory acceptance of alternative methods and implementation of testing strategies. (2018) (34)
Measurement of Apoptotic and Necrotic Cell Death in Primary Hepatocyte Cultures. (2015) (34)
Characterization and hepatic differentiation of skin-derived precursors from adult foreskin by sequential exposure to hepatogenic cytokines and growth factors reflecting liver development. (2009) (34)
Critical selection of reliable reference genes for gene expression study in the HepaRG cell line. (2011) (34)
Scientific Committee on Consumer Products SCCP (2007) (33)
The effect of two moisturisers on skin barrier damage in allergic contact dermatitis. (2002) (33)
Evaluation of biophysical and clinical parameters of skin barrier function among hospital workers (2002) (33)
Connexin32 hemichannels contribute to the apoptotic-to-necrotic transition during Fas-mediated hepatocyte cell death (2010) (33)
HS-GC-MS method for the analysis of fragrance allergens in complex cosmetic matrices. (2015) (33)
Stability of the long chain non-esterified fatty acid pattern in plasma and blood during different storage conditions. (1978) (33)
The Availability of Human Tissue for Biomedical Research: The Report and Recommendations of the ECVAM Workshop 32. (1998) (33)
Acute health risks related to the presence of cyanogenic glycosides in raw apricot kernels and products derived from raw apricot kernels (2016) (32)
Incorporation of ceramide 3B in dermatocosmetic emulsions: effect on the transepidermal water loss of sodium lauryl sulphate‐damaged skin (2000) (31)
Collagen-Gel Cultures of Rat Hepatocytes: (1998) (31)
Isolation of rat hepatocytes. (1998) (31)
Efficacy of topical corticosteroids in nickel‐induced contact allergy (2002) (30)
Epidermal Ceramidase Activity Regulates Epidermal Desquamation via Stratum Corneum Acidification (2008) (30)
Co-culture of primary rat hepatocytes with rat liver epithelial cells enhances interleukin-6-induced acute-phase protein response (2010) (30)
Transepidermal water loss measurements in patch test assessment: the need for standardisation. (1995) (30)
Current status of human adipose-derived stem cells: differentiation into hepatocyte-like cells. (2011) (30)
Primary hepatocyte cultures as prominent in vitro tools to study hepatic drug transporters (2013) (29)
The Potential Use of Non-invasive Methods in the Safety Assessment of Cosmetic Products (1999) (29)
The way forward for assessing the human health safety of cosmetics in the eu workshop proceedings. (2020) (28)
Analysis of Epidermal Lipids of the Healthy Human Skin: Factors Affecting the Design of a Control Population (2003) (28)
Adverse outcome pathways: hype or hope? (2013) (28)
A Metabolic Screening Study of Trichostatin A (TSA) and TSA-Like Histone Deacetylase Inhibitors in Rat and Human Primary Hepatocyte Cultures (2007) (28)
Primary hepatocytes and their cultures in liver apoptosis research (2014) (28)
Functional cardiotoxicity assessment of cosmetic compounds using human-induced pluripotent stem cell-derived cardiomyocytes (2017) (28)
Effect of phenobarbital on the expression of glutathione S‐transferase isoenzymes in cultured rat hepatocytes (1989) (28)
Sho‐saiko‐to: The right blend of traditional oriental medicine and liver cell biology (1999) (28)
OPINION ON SAFETY OF NANOMATERIALS IN COSMETIC PRODUCTS (2007) (27)
Current Status of Human Adipose–Derived Stem Cells: Differentiation into Hepatocyte-Like Cells (2011) (27)
Effect of rice starch as a bath additive on the barrier function of healthy but SLS-damaged skin and skin of atopic patients. (2002) (27)
Amide analogues of TSA: synthesis, binding mode analysis and HDAC inhibition. (2003) (26)
Hepatocyte Polarity and the Peroxisomal Compartment: A Comparative Study (2002) (26)
Cell morphology, albumin secretion and glutathione S-Transferase expression in collagen gel sandwich and immobilization cultures of rat hepatocytes. (1997) (26)
Effects of dimethylsulphoxide on phase I and II biotransformation in cultured rat hepatocytes. (1990) (26)
Proposal of an in silico profiler for categorisation of repeat dose toxicity data of hair dyes (2015) (26)
In vitro assessment of drug-induced liver steatosis based on human dermal stem cell-derived hepatic cells (2016) (26)
A multi-laboratory evaluation of cryopreserved monkey hepatocyte functions for use in pharmaco-toxicology. (1999) (25)
The application of an improved gas-liquid chromatographic method for the determination of the long chain non-esterified fatty acid pattern of blood plasma in children. (1977) (25)
EU legislations affecting safety data availability of cosmetic ingredients. (2007) (25)
Report from the EPAA workshop: in vitro ADME in safety testing used by EPAA industry sectors. (2011) (25)
Combination Therapy Improves the Recovery of the Skin Barrier Function: An Experimental Model Using a Contact Allergy Patch Test Combined with TEWL Measurements (2001) (24)
Linking existing in vitro dermal absorption data to physicochemical properties: Contribution to the design of a weight-of-evidence approach for the safety evaluation of cosmetic ingredients with low dermal bioavailability. (2016) (24)
Characterization of hepatic markers in human Wharton's Jelly-derived mesenchymal stem cells. (2014) (24)
Abnormal fatty acid pattern of the plasma cholesterol ester fraction in cystic fibrosis patients with and without pancreatic insufficiency (1983) (23)
Elafibranor restricts lipogenic and inflammatory responses in a human skin stem cell-derived model of NASH. (2019) (23)
Changes in expression and "de novo" synthesis of glutathione S-transferase subunits in cultured adult rat hepatocytes. (1990) (23)
Modulation of connexin signaling by bacterial pathogens and their toxins (2011) (23)
The SCCS notes of guidance for the testing of cosmetic ingredients and their safety evaluation - 10th revisionSCCS/1602/18 – Final version(ISSN : 1831-4767 ISBN : 978-92-76-00245-1 DOI : 10.2875/77673 Catalog Number : EW-AQ-19-012-EN-N) (2019) (23)
Evaluation of the multipotent character of human adipose tissue-derived stem cells isolated by Ficoll gradient centrifugation and red blood cell lysis treatment. (2011) (23)
Proliferative and phenotypical characteristics of human adipose tissue-derived stem cells: comparison of Ficoll gradient centrifugation and red blood cell lysis buffer treatment purification methods. (2014) (23)
Differentiation of neonatal rat epithelial cells from biliary origin into immature hepatic cells by sequential exposure to hepatogenic cytokines and growth factors reflecting liver development. (2007) (22)
Primary hepatocyte cultures as in vitro tools for toxicity testing: quo vadis? (2012) (22)
Gene expression and synthesis of fibronectin isoforms in rat hepatic stellate cells. comparison with liver parenchymal cells and skin fibroblasts (1997) (22)
Modifications in Connexin Expression in Liver Development and Cancer (2012) (22)
Measurement of reduced and oxidized glutathione in cultures of adult rat hepatocytes. (1991) (22)
Effect of ethanol on the expression of hepatic glutathione S-transferase: an in vivo/in vitro study. (2000) (21)
Application of in silico and in vitro methods in the development of adverse outcome pathway constructs in wildlife (2014) (21)
Transcriptional‐ and post‐transcriptional‐dependent regulation of glutathione S‐transferase expression in rat hepatocytes as a function of culture conditions (1992) (21)
Effect of oral intake of choline-stabilized orthosilicic acid on skin, nails and hair in women with photodamaged skin (2005) (21)
Biotransformation of trichloroethylene in collagen gel sandwich cultures of rat hepatocytes (2000) (21)
The novel histone deacetylase inhibitor 4-Me2N-BAVAH differentially affects cell junctions between primary hepatocytes. (2007) (21)
Testing chemical carcinogenicity by using a transcriptomics HepaRG-based model? (2014) (21)
Inhibition of NF‐κB activation by the histone deacetylase inhibitor 4‐Me2N‐BAVAH induces an early G1 cell cycle arrest in primary hepatocytes (2007) (21)
Safety Assessment of Cosmetics in Europe (2008) (20)
Synergetic effects of DNA demethylation and histone deacetylase inhibition in primary rat hepatocytes (2012) (20)
Characterization of spontaneous cell death in monolayer cultures of primary hepatocytes (2011) (20)
3.9. Toxicokinetics and Metabolism (2005) (20)
(Q)SAR tools for priority setting: A case study with printed paper and board food contact material substances. (2017) (20)
Comparison of hepatocarcinogen-induced gene expression profiles in conventional primary rat hepatocytes with in vivo rat liver (2012) (20)
Hepatocyte-based in vitro models and their application in pharmacotoxicology Report of an EC DGXII meeting with representatives of the European pharmaceutical industry. (1995) (20)
Retrospective analysis of the mutagenicity/genotoxicity data of the cosmetic ingredients present on the Annexes of the Cosmetic EU legislation (2000-12). (2014) (19)
Opportunities for an alternative integrating testing strategy for carcinogen hazard assessment? (2012) (19)
Kinetic Characteristics of Acidic and Alkaline Ceramidase in Human Epidermis (2007) (19)
Protocols in In Vitro Hepatocyte Research (2015) (18)
Spontaneous apoptosis, necrosis, energy status, glutathione levels and biotransformation capacities of isolated rat hepatocytes in suspension: effect of the incubation medium. (2005) (18)
Paving the way for application of next generation risk assessment to safety decision-making for cosmetic ingredients (2021) (18)
Effect of Trichostatin A on miRNA expression in cultures of primary rat hepatocytes. (2011) (18)
Collagen gel sandwich and immobilization cultures of rat hepatocytes: Problems encountered in expressing glutathione S-transferase activities. (1997) (18)
Regulation of glutathione S‐transferase gene expression by phenobarbital in cultured adult rat hepatocytes (1991) (17)
Silicones as Nonocclusive Topical Agents (2014) (17)
Regulation of glutathione S‐transferase subunits 3 and 4 in cultured rat hepatocytes (1989) (17)
Effect of the aging process on the gender and phenobarbital dependent expression of glutathione S-transferase subunits in brown Norway rat liver. (1991) (17)
A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment (2018) (17)
MicroRNAs as key regulators of xenobiotic biotransformation and drug response (2015) (16)
Seasonal Effects on the Nasolabial Skin Condition (2008) (16)
Cell cultures as in vitro tools for biotransformation studies (2002) (16)
Safety evaluation of traces of nickel and chrome in cosmetics: The case of Dead Sea mud. (2015) (16)
Hepatic cytosolic glutathione S-transferase activities in ageing Brown Norway rats — Importance of sex differences and phenobarbital treatment for studies of ageing (1990) (16)
Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data (2012) (16)
The inducing and inhibiting effects of sodium valproate in vivo on the biotransformation systems of xenobiotics in isolated rat hepatocytes. (1988) (16)
Human Skin‐Derived Precursor Cells Are Poorly Immunogenic and Modulate the Allogeneic Immune Response (2014) (16)
Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective (2016) (16)
The Impact of REACH (2007) (15)
In vitro Dermal Absorption: Sample Application and Seal Quality in a Franz Diffusion Cell System (2015) (15)
EU research activities in alternative testing strategies: current status and future perspectives (2009) (15)
Rat Hepatocyte Cultures : Conventional Monolayer and Cocultures With Rat Liver Epithelial Cells. (2006) (15)
Development and validation of a HS/GC–MS method for the simultaneous analysis of diacetyl and acetylpropionyl in electronic cigarette refills (2017) (15)
ON Use of the Threshold of Toxicological Concern ( TTC ) Approach for Human Safety Assessment of Chemical Substances with focus on Cosmetics and Consumer Products (2012) (15)
Effects of extracellular matrix on the expression of peroxisomes in primary rat hepatocyte cultures. (2000) (15)
Hepatocytes in suspension. (2006) (14)
Collagen-gel cultures of rat hepatocytes: collagen-gel sandwich and immobilization cultures. (1998) (14)
Gas chromatographic determination of the fatty acid pattern of red cell membrane plasmalogens in healthy children. (1980) (14)
Polymeric nanoreactors for enzyme replacement therapy of MNGIE. (2010) (14)
Efficacy claims of cosmetics in Europe must be scientifically substantiated from 1997 on (1995) (14)
Way forward in case of a false positive in vitro genotoxicity result for a cosmetic substance? (2014) (14)
Differential role of epigenetic modulators in malignant and normal stem cells: a novel tool in preclinical in vitro toxicology and clinical therapy (2007) (14)
The Impact of Cell-Expansion and Inflammation on The Immune-Biology of Human Adipose Tissue-Derived Mesenchymal Stromal Cells (2020) (14)
The SCCS guidance on the safety assessment of nanomaterials in cosmetics. (2020) (14)
Peroxisome Mosaics in the Liver of Patients and the Regulation of Peroxisome Expression in Rat Hepatocyte Cultures a (1996) (14)
Effect of epidermal growth factor in collagen gel cultures of rat hepatocytes. (1999) (13)
Effect of phenobarbital on 7-Ethoxycoumarin-O-deethylase and microsomal epoxide hydrase activities in collagen gel cultures of rat hepatocytes. (1997) (13)
Human hepatic in vitro models reveal distinct anti-NASH potencies of PPAR agonists (2020) (13)
Clarification on Opinion SCCS/1348/10 in the light of the Danish clause of safeguard banning the use of parabens in cosmetic products intended for children under three years of age (2011) (13)
Collagen Type I Gel Cultures of Adult Rat Hepatocytes as a Screening Induction Model for Cytochrome P450-dependent Enzymes (2001) (13)
Influence of culture system and medium enrichment on sulfotransferase and sulfatase expression in male rat hepatocyte cultures. (2001) (13)
Glutathione dependent detoxication in adult rat hepatocytes under various culture conditions (2005) (13)
In Vitro Study of the Incorporation and Transport of Nonesterified Fatty Acids into the Phospholipids of the Red Blood Cell Membranes of Cystic Fibrosis Patients (1982) (13)
Expression of flavin-containing monooxygenase activity in adult rat hepatocytes under various culture conditions. (1993) (12)
Metabolism of procyclidine in isolated rat hepatocytes. (1987) (12)
Evaluation of a new standardized enzymatic isolation protocol for human umbilical cord-derived stem cells. (2015) (12)
Database search for safety information on cosmetic ingredients. (2007) (12)
Biochemical Characterisation of an In Vitro Model of Hepatocellular Apoptotic Cell Death (2009) (12)
Proteomic and metabolomic responses to connexin43 silencing in primary hepatocyte cultures (2013) (12)
Technological advancements for the development of stem cell-based models for hepatotoxicity testing (2019) (12)
Isolation of rat bone marrow stem cells. (2006) (12)
The Vitotox and ToxTracker assays: A two-test combination for quick and reliable assessment of genotoxic hazards. (2016) (12)
Histone Deacetylase Inhibition: A Differentiation Therapy for Cultured Primary Hepatocytes? (2006) (12)
Practical Problems Encountered during the Cultivation of an Open-Source Reconstructed Human Epidermis Model on a Polycarbonate Membrane and Protein Quantification (2013) (12)
Effect of the histone deacetylase inhibitor trichostatin a on the metabolome of cultured primary hepatocytes. (2010) (12)
A review of national public funding programmes in European countries. (2008) (12)
Critical analysis of the SCCNFP/SCCP safety assessment of cosmetic ingredients (2000-2006). (2009) (11)
Screening of amide analogues of Trichostatin A in cultures of primary rat hepatocytes: search for potent and safe HDAC inhibitors (2009) (11)
Risks for human and animal health related to the presence of phorbol esters in Jatropha kernel meal. (2015) (11)
Comparative mutagenicity of 2-methylpropene (isobutene), its epoxide 2-methyl-1,2-epoxypropane and propylene oxide in the in vitro micronucleus test using human lymphocytes. (1995) (11)
Spectrophotometric measurement of flavin-containing monooxygenase activity in freshly isolated rat hepatocytes and their cultures. (1992) (11)
Coatings in food contact materials: Potential source of genotoxic contaminants? (2017) (11)
Critical analysis of the safety assessment of cosmetic ingredients performed at the European level. (2008) (11)
Effect of long-term ethanol exposure on the acinar distribution of hepatic glutathione S-transferase. (2000) (11)
In vitro biotransformation of 2-methylpropene (isobutene): Epoxide formation in mice liver (2005) (10)
Towards an integrated in vitro strategy for repeated dose toxicity testing (2011) (10)
DNA methyltransferase 3a expression decreases during apoptosis in primary cultures of hepatocytes. (2010) (10)
Rat Hepatocyte Cultures : Collagen Gel Sandwich and Immobilization Cultures. (2006) (10)
Evaluation of the multipotent character of human foreskin-derived precursor cells. (2011) (9)
Memorandum on hair dye Chemical Sensitisation (9)
Hepatic cells derived from human skin progenitors show a typical phospholipidotic response upon exposure to amiodarone. (2018) (9)
In silico tools and transcriptomics analyses in the mutagenicity assessment of cosmetic ingredients: a proof-of-principle on how to add weight to the evidence. (2016) (9)
Recent developments in the way forward for alternative methods: formation of national consensus platforms in Europe. (2005) (9)
Performance of In Silico Models for Mutagenicity Prediction of Food Contact Materials (2018) (9)
Measurement of malondialdehyde in cultures of adult rat hepatocytes. (1993) (9)
OPINION ON Titanium Dioxide (nano form) coated with Cetyl Phosphate, Manganese Dioxide or Triethoxycaprylylsilane as UV-filter in dermally applied cosmetic (2016) (9)
Measurement of Albumin Secretion as Functionality Test in Primary Hepatocyte Cultures. (2015) (9)
Effect of pyruvate on glutathione s-transferase expression in primary cultures of rat hepatocytes. (1997) (9)
Effects of valproate on xenobiotic biotransformation in rat liver (1992) (9)
Skin Efficacy and Biophysical Assessment of Glycerol-Containing Hydrocolloid Patches (2009) (9)
Species-dependent differences in biotransformation pathways of 2-methylpropene (isobutene). (1995) (9)
PPARβ regulates vitamin A metabolism-related gene expression in hepatic stellate cells undergoing activation Published, JLR Papers in Press, November 16, 2002. DOI 10.1194/jlr.M200376-JLR200 (2003) (8)
Good Science Must be the Key Factor in the Development and Use of Alternative Methods for Safety Assessment of Cosmetics (2006) (8)
Upregulation of sodium taurocholate cotransporter polypeptide during hepatogenic differentiation of umbilical cord matrix mesenchymal stem cells facilitates hepatitis B entry (2017) (8)
Effects of L-Proline on Phase I and Phase II Xenobiotic Biotransformation Capacities of Rat and Human Hepatocytes in Long-term Collagen Gel Cultures (2001) (8)
Modulation of CYP1A1 and CYP2B1 expression upon cell cycle progression in cultures of primary rat hepatocytes. (2007) (8)
Illegal cosmetics on the EU market: a threat for human health? (2014) (8)
Effect of Extracellular Matrix Composition on the Expression of Glutathione S-transferase Isoenzymes in Organotypical Hepatocyte Cultures. (1999) (8)
Emerging roles of connexin hemichannels in gastrointestinal and liver pathophysiology. (2010) (8)
Proliferation of Epidermal Growth Factor-stimulated Hepatocytes in a Hormonally Defined Serum-free Medium (2004) (8)
Prioritizing substances of genotoxic concern for in-depth safety evaluation using non-animal approaches: The example of food contact materials. (2018) (8)
Rat Hepatocyte Suspensions as a Suitable In Vitro Model for Studying the Biotransformation of Histone Deacetylase Inhibitors (2004) (8)
Safeguarding human health using in silico tools? (2017) (8)
Mutagenicity of 2-methylpropene (isobutene) and its epoxide in a modified Salmonella assay for volatile compounds. (1992) (8)
Triiodothyronine downregulates the periportal expression of α class glutathione S‐transferase in rat liver (2001) (8)
SCCP/SCHER/SCENIHR preliminary report on: the Use of the Threshold of Toxicological Concern (TTC) Approach for the Safety Assessment of Chemical Substances (2008) (7)
Transcriptional Profile of Cytokines, Regulatory Mediators and TLR in Mesenchymal Stromal Cells after Inflammatory Signaling and Cell-Passaging (2021) (7)
Fresh and cryopreserved cultured keratinocyte allografts for wound healing. (1991) (7)
Investigation of species differences in isobutene (2-methylpropene) metabolism between mice and rats (2005) (7)
Identification of flavouring substances of genotoxic concern present in e-cigarette refills. (2020) (7)
Safety assessment of cosmetic ingredients present in technical information files of finished products. (2008) (7)
Effects of phenobarbital and valproate on the expression of cytochromes P-450 in co-cultured rat hepatocytes. (1993) (7)
Differential effects of hydroxamate histone deacetylase inhibitors on cellular functionality and gap junctions in primary cultures of mitogen-stimulated hepatocytes. (2008) (7)
Rat Hepatocyte Cultures (2006) (7)
Scientific Committee on Consumer Safety SCCS Opinion on Nitrosamines and Secondary Amines in Cosmetic Products (2012) (7)
Hydroxypropyl-beta-cyclodextrin as delivery system for thyroid hormones, regulating glutathione S-transferase expression in rat hepatocyte co-cultures. (2001) (7)
Fatty acid pattern of platelet phospholipids in cystic fibrosis (1984) (7)
In vitro Dermal Absorption of Hydroquinone: Protocol Validation and Applicability on Illegal Skin-Whitening Cosmetics (2017) (7)
An overview of current practices for regulatory risk assessment with lessons learnt from cosmetics in the European Union (2021) (6)
Observation of hepatotoxic effects of 2-n-pentylaminoacetamide (Milacemide) in rat liver by a combined in vivo/ in vitro approach (1997) (6)
Comparative mutagenicity of structurally related aliphatic epoxides in a modified Salmonella/microsome assay. (1993) (6)
Purinergic signalling during sterile liver injury (2013) (6)
Age- and gender-related changes in the hepatic metabolism of 2-methylpropene and relationship to epoxide metabolizing enzymes (1994) (6)
Histone deacetylase inhibitors in multiple myeloma (2009) (6)
Metabolism and toxicity of 2-methylpropene (isobutene)--a review. (1997) (6)
Effect of tertiary butylhydroperoxide-induced oxidative stress on glutathione content and thiobarbituric acid reactive substances production in cultures and co-cultures of adult rat hepatocytes. (1996) (6)
Effect of ethanol on glutathione S-transferase expression in co-cultured rat hepatocytes. (1995) (5)
Gene expression data from acetaminophen-induced toxicity in human hepatic in vitro systems and clinical liver samples (2016) (5)
Effect of oxygen concentration on the expression of glutathione S-transferase activity in periportal and perivenous rat hepatocyte cultures. (2001) (5)
Development and characterization of a new human hepatic cell line (2015) (5)
Safety assessment of cosmetics in Europe. Preface. (2008) (5)
Human Skin-Derived Precursor Cells: Isolation, Expansion, and Hepatic Differentiation. (2015) (5)
Infections at the nexus of metabolic-associated fatty liver disease (2021) (5)
Focus on Stem Cells as Sources of Human Target Cells for In Vitro Research and Testing (5)
The SCCS Scientific Advice on the Safety of Nanomaterials in Cosmetics. (2021) (5)
Functionality Testing of Primary Hepatocytes in Culture by Measuring Urea Synthesis. (2015) (5)
ECOPA: The European Consensus Platform on Three Rs Alternatives (2004) (5)
Pyruvate-induced Long-term Maintenance of Glutathione S-Transferase in Rat Hepatocyte Cultures (2001) (5)
The use of alternative methods in the safety assessment of cosmetic ingredients. (2008) (5)
Chromatin remodelling , a novel strategy to expedite the hepatic differentiation of adult bone marrow stem cells in vitro (2006) (5)
A simple dilute‐and‐shoot method for screening and simultaneous quantification of nicotine and alkaloid impurities in electronic cigarette refills (e‐liquids) by UHPLC‐DAD (2019) (5)
Effects of Trichostatin A on drug uptake transporters in primary rat hepatocyte cultures (2015) (5)
Toxicity assessment of flavour chemicals used in e-cigarettes: current state and future challenges (2021) (5)
Animal-Free Cosmetics in Europe (2019) (4)
Ceramides/cholesterol/free fatty acids containing cosmetics : The effect on barrier function (1996) (4)
Headlines of safety assessment of cosmetics in Europe and future perspectives. (2008) (4)
Identification of potential biomarkers of hepatitis B-induced acute liver failure using hepatic cells derived from human skin precursors. (2015) (4)
Effect of Thyroid Hormones onFlavin-containing Monooxygenase Activity in Co-cultured Adult Rat Hepatocytes. (1998) (4)
Co-cultures of rat hepatocytes in the study of valproate toxicity. (1992) (4)
Glycerol as Humectant in Cosmetic Formulations (2016) (4)
Safety assessment of cosmetic ingredients by the SCCNFP: general principles (2003) (4)
Effects of lotioned disposable handkerchiefs on skin barrier recovery after tape stripping (2008) (4)
Ecopa: A Powerful Concept in the Way Forward for Alternative Methods (2002) (4)
[The role of intercellular communication via "gap junctions" in disease]. (2003) (4)
Reduced and oxidized glutathione contents in adult rat hepatocytes under various culture conditions (1991) (4)
New QSAR models to predict chromosome damaging potential based on the in vivo micronucleus test. (2020) (4)
Screening of Trichostatin Analogues Based on Cellular Potency in the Murine Multiple Myeloma 5T33MM Model (2008) (4)
Measurement of Cytochrome P450 Enzyme Induction and Inhibition in Human Hepatoma Cells. (2015) (4)
Interspecies differences in glutathione-dependent detoxication of hydroperoxides in short-term cultures of hepatocytes. (1996) (4)
Scientific Committee on Consumer Safety SCCS OPINION ON Vitamin A (Retinol, Retinyl Acetate, Retinyl Palmitate) (2016) (4)
Transcriptomics data of a human in vitro model of non-alcoholic steatohepatitis exposed to elafibranor (2019) (4)
The Rise of Three Rs Centres and Platforms in Europe* (2022) (4)
Impact of the revised European Tobacco Product Directive on the quality of e-cigarette refill liquids in Belgium. (2020) (3)
Analytical Techniques for Skin Lipids (2001) (3)
OPINION ON Sodium perborate and perboric acid (2010) (3)
OPINION ON the safety of cosmetic ingredients HEMA and Di-HEMA Trimethylhexyl Dicarbamate" - Submission I - (Sensitisation only) (2017) (3)
Identification of flavouring substances of genotoxic concern present in e-cigarette refills (2018) (3)
Epigenetic Modifications as Antidedifferentiation Strategy for Primary Hepatocytes in Culture. (2015) (3)
Increasing the Microfabrication Performance of Synthetic Hydrogel Precursors through Molecular Design. (2021) (3)
Opinion of the Scientific Committee on Consumer safety (SCCS) - Final Opinion on propylparaben (CAS No 94-13-3, EC No 202-307-7). (2021) (3)
Flow cytometric quantification of neutral lipids in a human skin stem cell-derived model of NASH (2020) (3)
A Safety Evaluation of Printed Paper and Board Contaminants: Photo-Initiators as a Case Study (2015) (3)
Current Status of Healthy Human Skin Models: Can Histone Deacetylase Inhibitors Potentially Improve the Present Replacement Models? (2013) (3)
OPINION ON salicylic acid (CAS 69-72-7) - Submission I"SCCS/1601/18 - Preliminary opinion (2018) (3)
3.5. Skin Absorption and Penetration (2005) (3)
MEMORANDUM ON THE USE OF IN SILICO METHODS FOR ASSESSMENT OF CHEMICAL HAZARD (2016) (3)
A liver-derived rat epithelial cell line from biliary origin acquires hepatic functions upon sequential exposure to hepatogenic growth factors and cytokines. (2012) (3)
Preliminary opinion on triclosan Antimicrobial Resistance (2010) (3)
Rat hepatocyte cultures. Conventional monolayer cultures and cocultures with rat liver epithelial cells. (1998) (3)
Modelling Long-Term Repeat-Dose Toxicity – Challenges Faced (2006) (3)
ON THE POTENTIAL HEALTH RISKS POSED BY CHEMICAL CONSUMER PRODUCTS RESEMBLING FOOD AND / OR HAVING CHILD-APPEALING PROPERTIES (2010) (3)
Effect of ceramides-containing lotions on the barrier function of the skin (1998) (3)
Is the replacement strategy, as it exists today in the EU for cosmetics, the way forward ? (2011) (3)
Screening of repeated dose toxicity data in safety evaluation reports of cosmetic ingredients issued by the Scientific Committee on Consumer Safety between 2009 and 2019 (2020) (3)
Cosmetic products and their current European regulatory framework. (2008) (3)
Inflammation Differentially Modulates the Biological Features of Adult Derived Human Liver Stem/Progenitor Cells (2020) (3)
Quantitative Risk Assessment in the EU of Cosmetics for Babies and Children (2015) (2)
ON Citric acid ( and ) Silver citrate (2010) (2)
"SCCS OPINION ON the safety of Aluminium in cosmetic products - Submission II" - SCCS/1613/19 - Preliminary Opinion (2019) (2)
SCCS OPINION ON Polyaminopropyl Biguanide (PHMB)- Submission III (2016) (2)
Preservation of hepatocellular functionality in cultures of primary rat hepatocytes upon exposure to 4-Me2N-BAVAH, a hydroxamate-based HDAC-inhibitor. (2011) (2)
Epigenetic Regulation of Myeloma Within Its Bone Marrow Microenvironment (2013) (2)
Comment to 'Letter to the editor: Human-based systems: Mechanistic NASH modelling just around the corner?' (2018) (2)
Clinical scoring and biophysical evaluation of nasolabial skin barrier damage caused by rhinorrhea (2008) (2)
In vitro assessment of drug-induced liver steatosis based on human dermal stem cell-derived hepatic cells (2015) (2)
"SCCS ADDENDUM to the scientific opinion on Zinc pyrithione (P81)" ref. SCCS/1512/13 - SCCS/1593/2018 Final Opinion (2018) (2)
“Watching the Detectives” report of the general assembly of the EU project DETECTIVE Brussels, 24–25 November 2015 (2016) (2)
ON reaction products of oxidative hair dye ingredients formed during hair dyeing processes (2011) (2)
Rat hepatocyte cultures: conventional monolayer and cocultures with rat liver epithelial cells. (2006) (2)
Opinion of the scientific committee on consumer safety (SCCS) - Final opinion on Polyaminopropyl Biguanide (PHMB) in cosmetic products - Submission III. (2017) (2)
Genetic and Epigenetic Modification of Rat Liver Progenitor Cells via HNF4α Transduction and 5’ Azacytidine Treatment: An Integrated miRNA and mRNA Expression Profile Analysis (2020) (2)
Consumer Safety SCCS Opinion on triclosan Antimicrobial Resistance (2010) (2)
Transcriptomics Reveals Discordant Lipid Metabolism Effects between In Vitro Models Exposed to Elafibranor and Liver Samples of NAFLD Patients after Bariatric Surgery (2022) (2)
Scientific Committee on Consumer Products SCCP MEMORANDUM on Actual Status of Alternative Methods on the Use of Experimental Animals in the Safety Assessment of Cosmetic Ingredients in the European Union (2007) (2)
Consumer protection provided by the European medical device and cosmetic legislation for condoms and lubricants (2019) (2)
Inhibition of NF‐κB activation by the histone deacetylase inhibitor 4‐Me2N‐BAVAH induces an early G1 cell cycle arrest in primary hepatocytes (2007) (2)
Junctional structures and hepatocellular carcinoma: from the lab to the clinic? (2008) (1)
Checklists for Applicants submitting dossiers on Cosmetic Ingredients to be evaluated by the SCCS (2017) (1)
Modified peroxisomes in primary hepatocyte cultures. (2003) (1)
Baby Care Products (2009) (1)
SCCS OPINION ON N,N'-Bis-(2-hydroxyethyl)-2-nitro-p-phenylenediamine (B34) (2016) (1)
Long-term preservation and induction of drug metabolizing enzymes in co-cultured rat hepatocytes. (1994) (1)
7-ECD Activity in vitro (1985) (1)
SCCS OPINION on Allergy Alert Test (AAT) as a proof-of-concept study"SCCS/1607/19 - Final Opinion (2019) (1)
Hepatocyte cultures in drug metabolism and toxicological research and testing. (1998) (1)
Challenges related to cosmetic safety assessment in the EU. (2008) (1)
Protocols in In Vitro Hepatocyte Research. Preface. (2015) (1)
Scientific Committee on Consumer Safety Sccs Opinion on Triclosan Antimicrobial Resistance Opinion on Triclosan – Antimicrobial Resistance 3 Acknowledgments (2010) (1)
Scientific Committee on Consumer Safety, memorandum (addendum) on the in vitro test EPISKIN for skin irritation testing (2011) (1)
SCCS OPINION ON water-soluble zinc salts used in oral hygiene products – Submission I (2017) (1)
RE-Place: A local initiative to pave the road towards international recognition and promotion of new approach methodologies (2020) (1)
Establishment and Characterization of an In Vitro Model of Fas-Mediated Hepatocyte Cell Death. (2015) (1)
The Current Regulatory Context in the European Union (2009) (1)
SCCS OPINION ON decamethylcyclopentasiloxane (cyclopentasiloxane, D5) in cosmetic products (2016) (1)
Opinion on the safety of Butylphenyl methylpropional (p-BMHCA) in cosmetic products - Submission II - SCCS/1591/17 - Final version (2020) (1)
Launch of the Belgian Platform for Alternative Methods (1999) (1)
1047 KERATIN 19: A KEY ROLE PLAYER IN THE INVASION OF HUMAN HEPATOCELLULAR CARCINOMAS (2013) (1)
Development and application of a novel method to assess exposure levels of sensitizing and irritating substances leaching from menstrual hygiene products (2021) (1)
SCCS (Scientific Committee on Consumer Safety), Opinion on triclosan, ADDENDUM to the SCCP Opinion on Triclosan (SCCP/1192/08) (2011) (1)
Effect of trichostatin A on miR-122 expression in primary hepatocyte cultures (1)
Effect of the aging process of gender and phenobarbital dependent glutathione S-transferase activity; subunit composition and steady rate mRNA in brown Norway rat liver (1991) (1)
Calcium regulation of connexin-43 hemichannel-mediated ATP release in glial cells (2009) (1)
From NAFLD to MAFLD: Aligning Translational In Vitro Research to Clinical Insights (2022) (1)
Dandruff is characterized by decreased levels of intercellular lipids in scalp stratum corneum (2002) (0)
Contents Vol. 202, 2001 (2001) (0)
Scientific Committee on Consumer Products SCCP OPINION ON Diethylene glycol (2008) (0)
284 Benzamide-based trichostatin a analogues are potent and metabolically stable inhibitors of histone deacetylase (2003) (0)
Omics-based in vitro verification of an adverse outcome pathway of cholestatic liver injury (2017) (0)
Contributions to Alternatives From The Netherlands, Belgium and France (2019) (0)
OPINION ON Melatonin (2010) (0)
Cell death communication via connexin channels investigated in a C6 glioma cell model. (2009) (0)
Contents Vol. 13, 2000 (2000) (0)
"SCCS OPINION on the safety of cosmetic ingredients Phenylene Bis-Diphenyltriazine (CAS No 55514-22-2)- S86 - Submission II"- SCCS/1594/18 Preliminary Opinion (2018) (0)
Cosmetics as a test case for non-animal testing? (2015) (0)
Liver-Specific miR-122 does Not Affect mRNA Levels of Cytochrome P 450 Enzymes and Nuclear Receptors in Primary Rat Hepatocyte Cultures (2012) (0)
Safeguarding human health using in silico tools? (2017) (0)
"SCCS OPINION ON Zinc Pyrithione (ZPT) (CAS No 13463-41-7) - Submission III" - SCCS/1614/19 - Preliminary Opinion (2019) (0)
Functional cardiotoxicity assessment of cosmetic compounds using human-induced pluripotent stem cell-derived cardiomyocytes (2017) (0)
"OPINION ON Dihydroxyacetone – DHA (1,3-Dihydroxy-2-propanone) CAS No. 96-26-4"SCCS/1612/19 - Preliminary Opinion (2019) (0)
Development of a “Freeze-Pour” Sample Preparation Method for the GC Analysis of Semivolatile Flavouring Chemicals Present in E-cigarette Refill Liquids (2021) (0)
Abstracts of the First Meeting of the Belgian Contact Group “Experimental Toxicology” (1988) (0)
SCCS OPINION ON hair dye Methylimidazoliumpropyl p-phenylenediamine HCl (A166) (CAS 220158-86-1) - Submission ISCCS/1609/19 - Preliminary Opinion (2019) (0)
COVID-19 and drug-induced liver injury: a problem of plenty or a petty point? (2020) (0)
A novel prediction model to evaluate genotoxicity based on a gene signature in metabolically competent human HepaRG? cells (2021) (0)
Variable peroxisome expression in different primary hepatocyte cultures. (Abstract) (2000) (0)
SCCS Final version of the Opinion on hair dye Tetrabromophenol Blue, 4,4’-(4,5,6,7-tetrabromo-1,1-dioxido-3H-2,1- benzoxathiol-3-yliden)bis-2,6-dibromophenol (C183) (2017) (0)
Screening of repeated dose toxicity data present in SCC(NF)P/SCCS safety evaluations of cosmetic ingredients (2011) (0)
SCCS OPINION ON Propylparaben - SCCS/1623/20 - Preliminary Opinion (2020) (0)
SCCS OPINION ON Dimethylpiperazinium Aminopyrazolopyridine HCl (A164) - SCCS/1584/17 – Final Version (2017) (0)
SCCS ADDENDUM TO THE OPINION ON Climbazole (P64) ref. SCCS/1506/13 (2017) (0)
Epoxide metabolozing enzymes in liver of young and old brown Norway rats (1991) (0)
Primary hepatocytes and their cultures in liver apoptosis research (2013) (0)
Are hepatocyte polarity and peroxisome expression related (2000) (0)
SCCS OPINION ON Phenoxyethanol (2016) (0)
MicroRNAs as key regulators of xenobiotic biotransformation and drug response (2014) (0)
"SCCS ADDENDUM to the scientific opinion on o-Phenylphenol, Sodium ophenylphenate and Potassium o-phenylphenate (SCCS/1555/15) - Here: the use as preservative of Sodium o-phenylphenate, Potassium o-phenylphenate, MEA o-Phenylphenate (CAS n. 132-27-4, 13707-65-8, 84145-04-0)" (2018) (0)
FATTY ACID TRANSPORT IN RED CELL MEMBRANES OF CYSTIC FIBROSIS PATIENTS AND HETEROZYGOTES (1981) (0)
SCCS Addendum to the scientific Opinion SCCS/1491/12 on the hair dye substance 2-methoxy-methyl-p-phenylenediamine and its sulfate salt - COLIPA n° A160 - Submission II – use on eyelashes - SCCS/1603/18 - Final Opinion (2019) (0)
Biophysical Assessment of Skin Desquamation and Scaliness Using Tape Strips and Adhesive Discs (2014) (0)
Vrije Universiteit Brussel Polymeric nanoreactors for enzyme replacement therapy by MNGIE (2010) (0)
Brussel Prioritizing substances of genotoxic concern for in-depth safety evaluation using non-animal approaches : The example of food contact materials (2019) (0)
Contents / List of abbreviations / Foreword / Preface (2008) (0)
ON 2-Amino-4-hydroxyethylaminoanisole sulfate COLIPA n ° A 84 (2008) (0)
Bo Holmstedt Memorial Fund (BHMF) Lecture human skin stem cell-derived hepatic cells and their potential applications (2017) (0)
Assessment of the intrinsic pluripotency of mesoderm-derived stem cells from different niches (2012) (0)
Evaluation of 3D-culture methods for the hepatic differentiation of human skin-derived stem cells (2018) (0)
Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data (2012) (0)
Human skin-derived precusor cells: A potential source for cellular therapy of the liver (2018) (0)
OPINION ON Trisodium nitrilotriacetate (NTA) (2012) (0)
Cancerous Contradictions : The Mis-Regulation of Human Carcinogens Based on Animal Data * (2006) (0)
Use of (Q)SAR tools as a first step in a strategy to assign priority to substances migrating from printed paper and board food contact materials based on genotoxic potential (2015) (0)
Subject Index Vol. 202, 2001 (2001) (0)
Corrigendum to: Impact of the Revised European Tobacco Product Directive on the Quality of E-cigarette Refill Liquids in Belgium. (2020) (0)
Original article: EFFECTS OF TRICHOSTATIN A ON DRUG UPTAKE TRANSPORTERS IN PRIMARY RAT HEPATOCYTE CULTURES (2015) (0)
Steatogenic compounds induce triglyceride accumulation by multiple mechanisms in hepatocyte-like cells generated from human skin-derived precursors (2017) (0)
SSC Final Opinion on Ethylzingerone - ‘Hydroxyethoxyphenyl Butanone’ (HEPB) - Cosmetics Europe No P98 - SCCS/1582/16 (2018) (0)
SCCS OPINION ON Basic Blue 99 (C059) - SCCS/1585/17 – Final Version (2018) (0)
Electron microscopical characterization of freshly isolated liver cells, and their use for northern hybridization analysis of connective tissue protein transcripts (1991) (0)
SCCS (Scientific Committee on Consumer Safety), opinion on nitrosamines and secondary amines in cosmetic products (2011) (0)
Appendix 1: The Transposition of Directive 76/768/EEC into Belgian Law: A Practical Example (2008) (0)
1079 PURIFICATION OF LIVER PROGENITOR CELLS BY USING ALDEHYDE DEHYDROGENASE ACTIVITY (2011) (0)
Book Chapter: Glycerol as humectant in cosmetic formulations (2009) (0)
"SCCS OPINION ON solubility of Synthetic Amorphous Silica (SAS)" - SCCS/1606/19 - Final Opinion - Corrigendum of 6 December 2019 (2019) (0)
The cosmetic technical information file in practice. (2008) (0)
In vitro biotransformation of 2-methylpropene (isobutene) in rat lung tissue in comparison with liver tissue (2009) (0)
Effects of RNA Interference-Mediated Suppression of Connexin 43 Production on the Expression of Differentiation Markers in Cultures of Adult Primary Rat Hepatocytes (2012) (0)
The Interplay between Epigenetics and Gap Junctional Intercellular Communication (2012) (0)
SCCS preliminary OPINION ON the safety of Butylphenyl methylpropional (p- BMHCA) in cosmetic products"- Submission II, ref CCS/1591/17 - Preliminary version (2017) (0)
Scientific Committee on Consumer Safety SCCS OPINION ON preservative EcoG (2016) (0)
Vrije Universiteit Brussel Prioritizing substances of genotoxic concern for in-depth safety evaluation using non- animal approaches: The example of food contact materials (2019) (0)
7 Eu cosmetic directive and requirements for toxicological evaluation of cosmetic ingredients (2003) (0)
196 In vitro pluripotency of human marrow mesenchymal stem cells (2003) (0)
SCCS OPINION on Resorcinol - SCCS/1619/20 - Preliminary Opinion (2020) (0)
SCCS SCIENTIFIC ADVICE ON the SCCS Opinion on methyl-N-methylanthranilate (MNM) (SCCS/1455/11) - SCCS/1616/20 – Final version (2020) (0)
A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment (2018) (0)
“Watching the Detectives” report of the general assembly of the EU project DETECTIVE Brussels, 24–25 November 2015 (2016) (0)
Elafibranor restores lipogenic gene expression in a human skin stem cell-derived non-alcoholic fatty liver disease (NAFLD) model (2018) (0)
Reprogramming of human umbilical cord-derived mesenchymal stromal cells into hepatocyte-like cells by over-expression of hepatocyte nuclear factor 1-alpha (2017) (0)
BLTK 1 murine Leydig tumor cells : a novel model for evaluating the steroidogenic effects of reproductive and developmental toxicants (2011) (0)
Quantitative risk assessment of allergens leaching from menstrual hygiene products. (2022) (0)
Human skin-derived precursors and their applications in hepatic toxicology (2018) (0)
Toxicogenomics directory of chemically exposed human hepatocytes (2014) (0)
Integrated testing strategies and in vitro-in vivo extrapolations : their role in chemical risk assessments (2011) (0)
The use of pyruvate supplemented monolayer cultures of hepatocytes to study the effect of triiodothyronine on glutathione S-transferase expression in rat liver. (1996) (0)
Isolation and hepatic differentiation of human adipose stem cells (2016) (0)
SCCS Opinion on Homosalate - SCCS/1622/20 - Preliminary Opinion (2020) (0)
An in vivo like expression pattern of CYP 450 enzymes found in a 3 D in vitro model of the human airway epithelium – MucilAir (0)
SCCS Final Opinion on Polyaminopropyl Biguanide (PHMB) - Submission III" - SCCS/1581/16 - Final version (2018) (0)
Corrigendum to "Hepatic cells derived from human skin progenitors show a typical phospholipidotic response upon exposure to amiodarone" [Toxicol. Lett. 284 (2018) 184-194]. (2020) (0)
Subject Index Vol. 13, 2000 (2000) (0)
SCCS OPINION ON hair dye 1 Indigofera tinctoria (C170) CAS 84775-63-3 - Submission III - SCCS/1615/20 - Preliminary Opinion (2020) (0)
SCCS OPINION ON Ethylzingerone – ‘Hydroxyethoxyphenyl Butanone’ (HEPB) (Cosmetics Europe No P98) (2016) (0)
RE-Place: A Unique Project Collecting Expertise on New Approach Methodologies (2022) (0)
Scientific Opinion on Acid Yellow 3 (submission II) - SCCS/1631/21. (2023) (0)
THE BIOSYNTHESIS OF PLASMA LIPOPROTEINS BY LIVER AND INTESTINAL MUCOSA IN THE RAINBOW TROUT (2009) (0)
Appendix 3: Proposed Frame work for a Cosmetic Technical Information File (2008) (0)
ON 6-Methoxy-2-methylamino-3-aminopyridine HCl (2008) (0)
Skin absorption and penetration. (2005) (0)
"Opinion on the safety of cosmetic ingredient Phenylene Bis-Diphenyltriazine (CAS No 55514-22-2) -S86 - Submission II" - SCCS/1594/18 - Final Version (2018) (0)
Brussels Symposium On Alternative Methods in Pharmacotoxicological Research (1991) (0)
Identification of potential genotoxic flavouring substances in e-cigarette refills using insilico tools (2018) (0)
Technological advancements for the development of stem cell-based models for hepatotoxicity testing (2019) (0)
The Impact of Reach Upon Animal use in the European Union - Report of the Conam Chemical Policy Working Group (2007) (0)
The Current Status and Work of Three Rs Centres and Platforms in Europe* (2022) (0)
Primary hepatocyte cultures for pharmaco-toxicological studies: at the busy crossroad of various anti-dedifferentiation strategies (2012) (0)
Safety evaluation of cosmetics in Europe (2002) (0)
Alpha hydroxy acids: a critial review of skin effects (1995) (0)
"SCCS OPINION ON Tetrabromophenol Blue, 4,4’-(4,5,6,7-tetrabromo-1,1-dioxido-3H-2,1-benzoxathiol-3-yliden)bis-2,6-dibromophenol (C183) - Submission IV"SCCS/1610/19 - Preliminary Opinion (2019) (0)
Vrije Universiteit Brussel Genetic and Epigenetic Modification of Rat Liver Progenitor Cells via HNF4α Transduction and 5’ Azacytidine Treatment: An Integrated miRNA and mRNA Expression Profile Analysis Bolleyn, (2020) (0)
SCCS OPINION ON Dimethylpiperazinium Aminopyrazolopyridine HCl (A164) (2017) (0)
Abstracts of papers clinical pharmacological meeting (2005) (0)
Illegal cosmetics on the EU market: a threat for human health? (2014) (0)
SCCS OPINION ON HC Orange No. 6 (B125) (2016) (0)
Proteomic and metabolomic responses to connexin43 silencing in primary hepatocyte cultures (2012) (0)
RE-Place: Centralizing information on alternative methods to animal testing to promote knowledge sharing (2018) (0)
Scientific Committee on Consumer Safety SCCS OPINION ON 2 , 4-Diaminophenoxyethanol dihydrochloride and sulfate COLIPA n ° A 42 (2011) (0)
Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells. (2022) (0)
Contents Vol. 29, 2016 (2017) (0)
SCCS scientific opinion on Butylated hydroxytoluene (BHT) - SCCS/1636/21″. (2022) (0)
"SCCS OPINION ON fragrance ingredient Acetylated Vetiver Oil - AVO (Vetiveria zizanioides root extract acetylated) - Submission III"SCCS/1599/18 – Final Opinion (2019) (0)
Human hepatic in vitro models reveal distinct anti-NASH potencies of PPAR agonists (2020) (0)
Lecture in Session VIII : (0)
Upregulation of sodium taurocholate cotransporter polypeptide during hepatogenic differentiation of umbilical cord matrix mesenchymal stem cells facilitates hepatitis B entry (2017) (0)
Adverse outcome pathways: hype or hope? (2013) (0)
Omics-based responses induced by bosentan in human hepatoma HepaRG cell cultures (2018) (0)
OPINION ON Ethylzingerone – ‘Hydroxyethoxyphenyl Butanone’ (HEPB) (2017) (0)
Comparison of hepatocarcinogen-induced gene expression profiles in conventional primary rat hepatocytes with in vivo rat liver (2012) (0)
PharmaNews / Pharma Ticker (2014) (0)
RE-Place: a database compiling New Approach Methodologies (2019) (0)
Opinion on fragrance ingredient Acetylated Vetiver Oil - AVO (Vetiveria zizanioides root extract acetylated) - Submission III - SCCS/1599/18 – Final Opinion – Corrigendum of 20 & 21 June 2019 (2020) (0)
Correction to: Toxicogenomics directory of chemically exposed human hepatocytes (2022) (0)
Rat hepatocyte cultures: collagen gel sandwich and immobilization cultures. (2006) (0)
Animal-free strategies to prioritize substances of concern: case studies with food contact materials (2018) (0)
Opinion on salicylic acid (CAS 69-72-7) - Submission ISCCS/1601/18 – Final Opinion(Ed. Publications Office of the European Union, Luxembourg, Luxembourg (70 pages) (2019) - ISSN : 1831-4767 - ISBN : 978-92-76-00244-4 - DOI : 10.2875/081047 - Catalog Number : EW-AQ-19-011-EN-N) (2019) (0)
Bio transformation EFFECTS OF PHENOBARBITAL AND VALPROATE ON THE EXPRESSION OF CYTOCHROMES P-450 IN CO-CULTURED RAT HEPATOCYTES (1993) (0)
Histone deacetylase inhibitors : Opening a new field of research in the development of alternative methods ? (2006) (0)
Scientific Committee on Consumer Products SCCP OPINION ON Polidocanol (Laureth-9) (2007) (0)
SCCS OPINION ON The safety of presence of Bisphenol A in clothing articles 2,2-bis(4-hydroxyphenyl)propane - SCCS/16/2020 - Preliminary Opinion (2020) (0)
Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective (2015) (0)
Validated Alternative Methods Available for Human Health Safety Assessment of Cosmetic Products and Their Ingredients in the European Union (2014) (0)
Development of an in silico model to evaluate in vivo chromosome damaging potential of chemicals (2018) (0)
SCCS OPINION ON Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate (S87) - Submission I" (2017) (0)
SCCS addendum to the opinion Climbazole (P64) - SCCS/1506/13 (2018) (0)
Proposal of an in silico profiler for categorisation of repeat dose toxicity data of hair dyes (2014) (0)
Opinion on salicylic acid (CAS 69-72-7) - Submission I - SCCS/1601/18 - Final Opinion – Corrigendum of 20 & 21 June 2019 (2020) (0)
Appendix 4: Data Input Forms: General Information (2008) (0)
SCCS OPINION ON Basic Blue 99 (C059) (2017) (0)

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Vrije Universiteit Brussel

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