Vernon E. Steele
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Vernon E. Steelebiology Degrees
Biology
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Biochemistry
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Chemistry Biology
Vernon E. Steele's Degrees
- PhD Biochemistry University of California, Berkeley
- Masters Chemistry Stanford University
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(Suggest an Edit or Addition)Vernon E. Steele's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Chemopreventive effect of curcumin, a naturally occurring anti-inflammatory agent, during the promotion/progression stages of colon cancer. (1999) (648)
- Chemoprevention of colon cancer by specific cyclooxygenase-2 inhibitor, celecoxib, administered during different stages of carcinogenesis. (2000) (496)
- Chemoprevention of colon carcinogenesis by sulindac, a nonsteroidal anti-inflammatory agent. (1995) (446)
- Downregulation of microRNA expression in the lungs of rats exposed to cigarette smoke (2009) (439)
- Progress in cancer chemoprevention: development of diet-derived chemopreventive agents. (2000) (423)
- Modulation of apoptosis by sulindac, curcumin, phenylethyl-3-methylcaffeate, and 6-phenylhexyl isothiocyanate: apoptotic index as a biomarker in colon cancer chemoprevention and promotion. (1997) (318)
- Screening of potential chemopreventive agents using biochemical markers of carcinogenesis. (1994) (306)
- Effects of the phytochemicals, curcumin and quercetin, upon azoxymethane-induced colon cancer and 7,12-dimethylbenz[a]anthracene-induced mammary cancer in rats. (1996) (279)
- Celecoxib inhibits N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced urinary bladder cancers in male B6D2F1 mice and female Fischer-344 rats. (2000) (277)
- Chemoprevention of chemically-induced mammary carcinogenesis by indole-3-carbinol. (1995) (268)
- Efficacy of potential chemopreventive agents on rat colon aberrant crypt formation and progression. (2000) (266)
- Lipoxygenase inhibitors as potential cancer chemopreventives. (1999) (250)
- Chemopreventive drug development: perspectives and progress. (1994) (236)
- Use of azoxymethane-induced foci of aberrant crypts in rat colon to identify potential cancer chemopreventive agents. (1994) (231)
- Chemoprevention of colon carcinogenesis by dietary perillyl alcohol. (1997) (215)
- Aberrant crypts as a biomarker for colon cancer: evaluation of potential chemopreventive agents in the rat. (1996) (212)
- Enhancement of experimental colon cancer by genistein. (1997) (192)
- Comparative chemopreventive mechanisms of green tea, black tea and selected polyphenol extracts measured by in vitro bioassays. (2000) (189)
- Preclinical efficacy evaluation of potential chemopreventive agents in animal carcinogenesis models: Methods and results from the NCI chemoprevention drug development program (1994) (178)
- Chemoprevention studies of the flavonoids quercetin and rutin in normal and azoxymethane-treated mouse colon. (2000) (177)
- Targeting the AKT protein kinase for cancer chemoprevention (2007) (176)
- Relationships of microRNA expression in mouse lung with age and exposure to cigarette smoke and light (2009) (171)
- Progress in Cancer Chemoprevention (1999) (165)
- Mechanistic considerations in chemopreventive drug development (1994) (165)
- Natural history of intraepithelial neoplasia in humans with implications for cancer chemoprevention strategy. (1992) (161)
- Is inducible nitric oxide synthase a target for chemoprevention? (2003) (153)
- Risk biomarkers and current strategies for cancer chemoprevention (1996) (146)
- Strategy and planning for chemopreventive drug development: Clinical development plans II (1994) (141)
- Chemoprevention of familial adenomatous polyposis by low doses of atorvastatin and celecoxib given individually and in combination to APCMin mice. (2006) (140)
- Chemoprevention of pulmonary carcinogenesis by brief exposures to aerosolized budesonide or beclomethasone dipropionate and by the combination of aerosolized budesonide and dietary myo-inositol. (2000) (139)
- Chemoprevention of pulmonary carcinogenesis by aerosolized budesonide in female A/J mice. (1997) (133)
- Antidiabetic Drug Metformin Prevents Progression of Pancreatic Cancer by Targeting in Part Cancer Stem Cells and mTOR Signaling. (2013) (131)
- New agents for cancer chemoprevention (1996) (131)
- Progress in cancer chemoprevention: perspectives on agent selection and short-term clinical intervention trials. (1994) (130)
- In situ detection of neoplastic transformation and chemopreventive effects in rat esophagus epithelium using angle-resolved low-coherence interferometry. (2003) (126)
- Effect of retinoids on AOM-induced colon cancer in rats: modulation of cell proliferation, apoptosis and aberrant crypt foci. (1999) (120)
- Chemopreventive efficacy of sulindac sulfone against colon cancer depends on time of administration during carcinogenic process. (1999) (116)
- Chemoprevention of Cigarette Smoke–Induced Alterations of MicroRNA Expression in Rat Lungs (2010) (115)
- Chemoprevention of Prostate Cancer: Concepts and Strategies (1999) (114)
- Chemopreventive efficacy of arylalkyl isothiocyanates and N-acetylcysteine for lung tumorigenesis in Fischer rats. (1996) (109)
- Apoptosis, cell replication, and Western-style diet-induced tumorigenesis in mouse colon. (1996) (108)
- Dose-responsiveness and persistence of microRNA expression alterations induced by cigarette smoke in mouse lung. (2011) (108)
- Nitric oxide–releasing aspirin and indomethacin are potent inhibitors against colon cancer in azoxymethane-treated rats: effects on molecular targets (2006) (105)
- Prevention of azoxymethane-induced colon cancer by combination of low doses of atorvastatin, aspirin, and celecoxib in F 344 rats. (2006) (104)
- Strategy and planning for chemopreventive drug development: Clinical development plans (1996) (102)
- Modulation of microRNA expression by budesonide, phenethyl isothiocyanate and cigarette smoke in mouse liver and lung. (2010) (101)
- Approaches to the development and marketing approval of drugs that prevent cancer. (1995) (101)
- Differential activity of aspirin, ketoprofen and sulindac as cancer chemopreventive agents in the mouse urinary bladder. (1996) (101)
- Prevention by aspirin and its combination with alpha-difluoromethylornithine of azoxymethane-induced tumors, aberrant crypt foci and prostaglandin E2 levels in rat colon. (1999) (100)
- Mechanisms and applications of non-steroidal anti-inflammatory drugs in the chemoprevention of cancer. (2003) (100)
- Cancer chemoprevention agent development strategies for genistein. (1995) (96)
- Screening for chemopreventive (anticarcinogenic) compounds in rodents. (1992) (92)
- Inhibition of transformation in cultured rat tracheal epithelial cells by potential chemopreventive agents. (1990) (90)
- Chemoprevention of rat prostate carcinogenesis by 9-cis-retinoic acid. (1999) (89)
- Epidermal growth factor receptor tyrosine kinase inhibitors as potential cancer chemopreventives. (1996) (87)
- Chemoprevention of rat prostate carcinogenesis by early and delayed administration of dehydroepiandrosterone. (1999) (82)
- Chemoprevention by lipoxygenase and leukotriene pathway inhibitors of vinyl carbamate-induced lung tumors in mice. (2002) (81)
- Aromatase inhibitors as potential cancer chemopreventives. (1998) (81)
- Influence of N-methyl-N-nitrosourea, testosterone, and N-(4-hydroxyphenyl)-all-trans-retinamide on prostate cancer induction in Wistar-Unilever rats. (1998) (79)
- Mechanisms of nonsteroidal anti-inflammatory drugs in cancer prevention. (2016) (78)
- Potent carcinogenicity of cigarette smoke in mice exposed early in life. (2007) (77)
- Energy Homeostasis and Cancer Prevention: The AMP-Activated Protein Kinase (2009) (77)
- Rosiglitazone, a PPAR gamma agonist: Potent promoter of hydroxybutyl(butyl)nitrosamine‐induced urinary bladder cancers (2008) (76)
- Progress in clinical chemoprevention. (1997) (76)
- Growth kinetics and chemoprevention of aberrant crypts in the rat colon (1992) (75)
- Effect of chemopreventive agents on separate stages of progression of benzo[alpha]pyrene induced lung tumors in A/J mice. (2003) (74)
- Protective action of plant polyphenols on radiation-induced chromatid breaks in cultured human cells. (1998) (73)
- Chemoprevention of OH-BBN-induced bladder cancer in mice by piroxicam. (1993) (72)
- Atorvastatin delays progression of pancreatic lesions to carcinoma by regulating PI3/AKT signaling in p48Cre/+ LSL‐KrasG12D/+ mice (2012) (70)
- Prevention of cigarette smoke–induced lung tumors in mice by budesonide, phenethyl isothiocyanate, and N‐acetylcysteine (2009) (69)
- Chemopreventive efficacy of anethole trithione, N‐acetyl‐L‐cysteine, miconazole and phenethylisothiocyanate in the DMBA‐induced rat mammary cancer model (1997) (68)
- Agents, biomarkers, and cohorts for chemopreventive agent development in prostate cancer. (2001) (68)
- Chemoprevention of MNU-induced mammary tumors in the mature rat by 4-HPR and tamoxifen. (1992) (68)
- Prevention by retinoids of azoxymethane-induced tumors and aberrant crypt foci and their modulation of cell proliferation in the colon of rats. (1997) (66)
- Prospective grading of neoplastic change in rat esophagus epithelium using angle-resolved low-coherence interferometry. (2005) (65)
- Chemopreventive effects of the aromatase inhibitors vorozole (R-83842) and 4-hydroxyandrostenedione in the methylnitrosourea (MNU)-induced mammary tumor model in Sprague-Dawley rats. (1994) (64)
- Surrogate endpoint biomarkers for phase II cancer chemoprevention trials. (1994) (59)
- Prevention of mouse lung tumors by budesonide and its modulation of biomarkers. (2002) (59)
- Combination of Atorvastatin with Sulindac or Naproxen Profoundly Inhibits Colonic Adenocarcinomas by Suppressing the p65/β-Catenin/Cyclin D1 Signaling Pathway in Rats (2011) (59)
- K-ras mutations in lung tumors from A/J and A/J x TSG-p53 F1 mice treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and phenethyl isothiocyanate. (1995) (58)
- Strategies for identification and clinical evaluation of promising chemopreventive agents. (1996) (58)
- Chemoprevention of Colon and Small Intestinal Tumorigenesis in APCMin/+ Mice by Licofelone, a Novel Dual 5-LOX/COX Inhibitor: Potential Implications for Human Colon Cancer Prevention (2011) (56)
- Enhancement of experimental colon carcinogenesis by dietary 6-phenylhexyl isothiocyanate. (1995) (56)
- Effect of Tea Extracts, Polyphenols, and Epigallocatechin Gallate on Azoxymethane-induced Colon Cancer (1998) (56)
- The use of animal models for cancer chemoprevention drug development. (2010) (55)
- Altered expression of c-myc, p16 and p27 in rat colon tumors and its reversal by short-term treatment with chemopreventive agents. (2002) (54)
- Effects of theaflavins on N-nitrosomethylbenzylamine-induced esophageal tumorigenesis. (1997) (53)
- Chemoprevention of Rat Prostate Carcinogenesis by Soy Isoflavones and by Bowman-Birk Inhibitor (2007) (53)
- Exceptional chemopreventive activity of low-dose dehydroepiandrosterone in the rat mammary gland. (1996) (53)
- Use of in vitro assays to predict the efficacy of chemopreventive agents in whole animals (1996) (53)
- Null Activity of Selenium and Vitamin E as Cancer Chemopreventive Agents in the Rat Prostate (2010) (52)
- Cellular and Molecular Targets for Chemoprevention (1992) (51)
- Chemoprevention clinical trials. (1992) (51)
- Smoke‐induced microRNA and related proteome alterations. Modulation by chemopreventive agents (2012) (51)
- Chemoprevention of Colon Carcinogenesis by Oleanolic Acid and Its Analog in Male F344 Rats and Modulation of COX-2 and Apoptosis in Human Colon HT-29 Cancer Cells (2008) (50)
- The Epidermal Growth Factor Receptor Inhibitor Gefitinib Prevents the Progression of Pancreatic Lesions to Carcinoma in a Conditional LSL-KrasG12D/+ Transgenic Mouse Model (2010) (50)
- Effects of novel phenylretinamides on cell growth and apoptosis in bladder cancer. (2001) (49)
- Properties of intraepithelial neoplasia relevant to the development of cancer chemopreventive agents (1997) (49)
- Modulation of in vitro biomarkers of the carcinogenic process by chemopreventive agents. (1999) (49)
- Current mechanistic approaches to the chemoprevention of cancer. (2003) (49)
- Chemopreventive Effects of Frondanol A5, a Cucumaria frondosa Extract, against Rat Colon Carcinogenesis and Inhibition of Human Colon Cancer Cell Growth (2010) (48)
- Eflornithine (DFMO) Prevents Progression of Pancreatic Cancer by Modulating Ornithine Decarboxylase Signaling (2014) (48)
- Development of cancer chemopreventive drugs based on mechanistic approaches. (2005) (47)
- Modulation of methylnitrosourea-induced breast cancer in Sprague Dawley rats by dehydroepiandrosterone: dose-dependent inhibition, effects of limited exposure, effects on peroxisomal enzymes, and lack of effects on levels of Ha-Ras mutations. (1998) (47)
- Chemopreventive Efficacy of Naproxen and Nitric Oxide–naproxen in Rodent Models of Colon, Urinary Bladder, and Mammary Cancers (2009) (47)
- Intermediate biomarkers of precancer and their application in chemoprevention (1992) (47)
- β-Ionone inhibits colonic aberrant crypt foci formation in rats, suppresses cell growth, and induces retinoid X receptor-α in human colon cancer cells (2008) (47)
- Temporal sequence of mammary intraductal proliferations, ductal carcinomas in situ and adenocarcinomas induced by 1-methyl-1-nitrosourea in rats. (1998) (46)
- Evaluation of chemopreventive agents in different mechanistic classes using a rat tracheal epithelial cell culture transformation assay. (1995) (46)
- MicroRNAs as targets for dietary and pharmacological inhibitors of mutagenesis and carcinogenesis. (2012) (46)
- CHEMOPREVENTION OF VINYL CARBAMATE-INDUCED LUNG TUMORS IN STRAIN A MICE (2000) (45)
- Induction of apoptosis by 1,4-phenylenebis(methylene)selenocyanate in cultured human colon cancer cells. (2002) (45)
- Chemoprevention of OH-BBN-induced bladder cancer in mice by oltipraz, alone and in combination with 4-HPR and DFMO. (1994) (45)
- Clinical development plan: N-(4-hydroxyphenyl)retinamide. (1994) (45)
- Inhibition of pancreatic intraepithelial neoplasia progression to carcinoma by nitric oxide-releasing aspirin in p48(Cre/+)-LSL-Kras(G12D/+) mice. (2012) (45)
- Mechanistic considerations in the evaluation of chemopreventive data. (1996) (44)
- Potential use of lipoxygenase inhibitors for cancer chemoprevention (2000) (43)
- Recent results in preclinical and clinical drug development of chemopreventive agents at the National Cancer Institute. (1993) (43)
- Chemoprevention of benzo(a)pyrene-induced lung tumors in mice by the farnesyltransferase inhibitor R115777. (2003) (43)
- Piroxicam-induced regression of azoxymethane-induced aberrant crypt foci and prevention of colon cancer in rats. (1996) (43)
- Efficacy of Targretin on methylnitrosourea-induced mammary cancers: prevention and therapy dose-response curves and effects on proliferation and apoptosis. (2004) (42)
- Interplay between histopathological alterations, cigarette smoke and chemopreventive agents in defining microRNA profiles in mouse lung. (2011) (41)
- Clinical development plans for cancer chemopreventive agents (1996) (41)
- Chemopreventive effects of the aromatase inhibitor vorozole (R 83842) in the methylnitrosourea-induced mammary cancer model. (1998) (41)
- Chemopreventive effects of RXR-selective rexinoid bexarotene on intestinal neoplasia of Apc(Min/+) mice. (2012) (40)
- Farnesyl protein transferase inhibitors as potential cancer chemopreventives. (1997) (40)
- Establishment of epithelial cell lines following exposure of cultured tracheal epithelium to 12-O-tetradecanoyl-phorbol-13-acetate. (1978) (40)
- Modulation by celecoxib and difluoromethylornithine of the methylation of DNA and the estrogen receptor-alpha gene in rat colon tumors. (2004) (40)
- Targeting pancreatitis blocks tumor-initiating stem cells and pancreatic cancer progression (2015) (39)
- Estrogen Receptor-β as a Potential Target for Colon Cancer Prevention: Chemoprevention of Azoxymethane-Induced Colon Carcinogenesis by Raloxifene in F344 Rats (2009) (38)
- Selection of cancer chemopreventive agents based on inhibition of topoisomerase II activity. (2000) (38)
- Prenatal N-acetylcysteine prevents cigarette smoke-induced lung cancer in neonatal mice. (2009) (38)
- Inhibition of 2-Amino-1-methyl-6-phenylimidazo[4,5]pyridine-induced lymphoma formation by oltipraz. (1996) (38)
- Overexpression of Cyclooxygenase-2 in Rat Oral Cancers and Prevention of Oral Carcinogenesis in Rats by Selective and Nonselective COX Inhibitors (2010) (38)
- Lack of Efficacy of the Statins Atorvastatin and Lovastatin in Rodent Mammary Carcinogenesis (2009) (37)
- Properties of Intraepithelial Neoplasia Relevant to Cancer Chemoprevention and to the Development of Surrogate End Points for Clinical Trials (1997) (37)
- Characterization of rat ovarian adenocarcinomas developed in response to direct instillation of 7,12-dimethylbenz[a]anthracene (DMBA) coated suture. (2005) (37)
- Low doses of β‐carotene and lutein inhibit AOM‐induced rat colonic ACF formation but high doses augment ACF incidence (2005) (37)
- Chemoprevention of MNU-induced mammary tumorigenesis by hormone response modifiers: toremifene, RU 16117, tamoxifen, aminoglutethimide and progesterone. (1994) (36)
- Anti-carcinogenic properties of omeprazole against human colon cancer cells and azoxymethane-induced colonic aberrant crypt foci formation in rats. (2011) (36)
- Preventive effects of Polyphenon E on urinary bladder and mammary cancers in rats and correlations with serum and urine levels of tea polyphenols (2007) (36)
- Dehydroepiandrosterone inhibits the progression phase of mammary carcinogenesis by inducing cellular senescence via a p16-dependent but p53-independent mechanism (2005) (36)
- S‐adenosyl L‐methionine inhibits azoxymethane‐induced colonic aberrant crypt foci in F344 rats and suppresses human colon cancer Caco‐2 cell growth in 3D culture (2008) (36)
- Inhibition of lung tumor development by berry extracts in mice exposed to cigarette smoke (2012) (35)
- Retinoid receptor-dependent and independent biological activities of novel fenretinide analogues and metabolites. (2003) (35)
- Oncogenic transformation in epithelial cell lines derived from tracheal explants exposed in vitro to N-methyl-N'-NITRO-N-nitrosoguanidine. (1979) (34)
- A quantitative angiogenesis model for efficacy testing of chemopreventive agents. (2001) (34)
- Screening agents for preventive efficacy in a bladder cancer model: study design, end points, and gefitinib and naproxen efficacy. (2010) (34)
- Transformation of tracheal epithelium exposed in vitro to N‐methyl‐N′‐nitro‐N‐nitrosoguanidine (MNNG) (1977) (34)
- Studies of neoplastic development in respiratory tract epithelium. (1981) (34)
- Differential carcinogenicity of cigarette smoke in mice exposed either transplacentally, early in life or in adulthood (2012) (34)
- Identification of retinamides that are more potent than N-(4-hydroxyphenyl)retinamide in inhibiting growth and inducing apoptosis of human head and neck and lung cancer cells. (2001) (33)
- Chemopreventive potential of fumaric acid, N-acetylcysteine, N-(4-hydroxyphenyl) retinamide and beta-carotene for tobacco-nitrosamine-induced lung tumors in A/J mice. (1998) (33)
- Exposure of mice to cigarette smoke and/or light causes DNA alterations in heart and aorta. (2008) (32)
- Evaluation of two in vitro assays to screen for potential developmental toxicants. (1988) (32)
- Differential response of normal, premalignant and malignant human oral epithelial cells to growth inhibition by chemopreventive agents. (2000) (31)
- Cytokeratin, lectin, and acidic mucin modulation in differentiating colonic epithelial cells of mice after feeding Western-style diets. (1996) (31)
- Inhibition of azoxymethane-induced colorectal cancer by CP-31398, a TP53 modulator, alone or in combination with low doses of celecoxib in male F344 rats. (2009) (31)
- Development of chemopreventive agents for bladder cancer (1992) (31)
- Preclinical efficacy studies of green and black tea extracts. (1999) (31)
- Pharmacological Modulation of Lung Carcinogenesis in Smokers: Preclinical and Clinical Evidence. (2016) (30)
- Cell Proliferation, Apoptosis, and Expression of Cyclin D1 and Cyclin E as Potential Biomarkers in Tamoxifen-Treated Mammary Tumors (2003) (30)
- Chemoprevention by indomethacin of N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced urinary bladder tumors. (1993) (30)
- 4-Hydroxybutyl(butyl)nitrosamine-induced urinary bladder cancers in mice: characterization of FHIT and survivin expression and chemopreventive effects of indomethacin. (2004) (30)
- Chemopreventive agents induce a senescence-like phenotype in rat mammary tumours. (2003) (30)
- High susceptibility of neonatal mice to molecular, biochemical and cytogenetic alterations induced by environmental cigarette smoke and light. (2008) (29)
- Induction of atypical ductal hyperplasia in mouse mammary gland organ culture. (2001) (29)
- Oxidative stress in the lung of mice exposed to cigarette smoke either early in life or in adulthood (2013) (29)
- 9-cis-retinoic acid but not 4-(hydroxyphenyl)retinamide inhibits prostate intraepithelial neoplasia in Noble rats. (2002) (29)
- In situ Assessment of Intraepithelial Neoplasia in Hamster Trachea Epithelium Using Angle-Resolved Low-Coherence Interferometry (2007) (28)
- Preneoplastic and neoplastic lesions in the lung, liver and urinary tract of mice exposed to environmental cigarette smoke and UV light since birth (2008) (28)
- Effect of budesonide on the methylation and mRNA expression of the insulin‐like growth factor 2 and c‐myc genes in mouse lung tumors (2002) (28)
- Comparative metabolism of benzo(a)pyrene in organ and cell cultures derived from rat tracheas. (1979) (28)
- Prevention of mouse lung tumors by targretin (2006) (28)
- Strategies for phase II cancer chemoprevention trials: Cervix, endometrium, and ovary (1995) (27)
- Neoplastic transformation of mammary epithelial cells in rats is associated with decreased apoptotic cell death. (2000) (27)
- Preclinical drug development paradigms for chemopreventives. (1998) (27)
- Chemopreventive effect of S-methylmethane thiosulfonate and sulindac administered together during the promotion/progression stages of colon carcinogenesis. (1999) (27)
- Simultaneous targeting of 5-LOX-COX and EGFR blocks progression of pancreatic ductal adenocarcinoma (2015) (26)
- Piroxicam selectively inhibits the growth of premalignant and malignant human oral cell lines by limiting their progression through the S phase and reducing the levels of cyclins and AP‐1 (2003) (26)
- Effect of calcium on azoxymethane-induced aberrant crypt foci and cell proliferation in the colon of rats. (1998) (26)
- Introductory remarks: Development of chemopreventive agents for prostate cancer (1992) (26)
- The chemopreventive efficacy of inhaled oltipraz particulates in the B[a]P-induced A/J mouse lung adenoma model. (2005) (26)
- Lack of Effect of Metformin on Mammary Carcinogenesis in Nondiabetic Rat and Mouse Models (2015) (26)
- Cigarette smoke induces DNA damage and alters base-excision repair and tau levels in the brain of neonatal mice. (2011) (26)
- Modulation by metformin of molecular and histopathological alterations in the lung of cigarette smoke-exposed mice (2014) (25)
- AKT and the phosphatidylinositol 3-kinase/AKT pathway: important molecular targets for lung cancer prevention and treatment. (2003) (25)
- Enhancement of Carcinogenesis in Cultured Respiratory Tract Epithelium by 12‐O‐Tetradecanoylphorbol‐13‐Acetate (1980) (25)
- Relationships between pulmonary micro-RNA and proteome profiles, systemic cytogenetic damage and lung tumors in cigarette smoke-exposed mice treated with chemopreventive agents. (2013) (25)
- Modulation by budesonide of DNA methylation and mRNA expression in mouse lung tumors (2006) (25)
- Termination of piroxicam treatment and the occurrence of azoxymethane-induced colon cancer in rats. (1999) (25)
- Development of breast cancer chemopreventive drugs (1993) (24)
- Lack of chemopreventive efficacy of DL-selenomethionine in colon carcinogenesis. (2000) (24)
- Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis (2015) (24)
- Induction and prevention of carcinogen-induced precancerous lesions in mouse mammary gland organ culture (1997) (24)
- Effects of 5,6-benzoflavone, indole-3-carbinol (I3C) and diindolylmethane (DIM) on chemically-induced mammary carcinogenesis: is DIM a substitute for I3C? (2011) (24)
- Modulation of DNA hypomethylation as a surrogate endpoint biomarker for chemoprevention of colon cancer (2004) (23)
- N-(4-Hydroxyphenyl)retinamide is more potent than other phenylretinamides in inhibiting the growth of BRCA1-mutated breast cancer cells. (2005) (23)
- Differential activity of NO synthase inhibitors as chemopreventive agents in a primary rat tracheal epithelial cell transformation system. (2002) (23)
- Evaluation of a rat tracheal epithelial cell culture assay system to identify respiratory carcinogens (1989) (23)
- Comparative activity of N-(4-hydroxyphenyl)-all-trans-retinamide and alpha-difluoromethylornithine as inhibitors of lymphoma induction in PIM transgenic mice. (1996) (22)
- Release of MicroRNAs into Body Fluids from Ten Organs of Mice Exposed to Cigarette Smoke (2018) (22)
- Preclinical Animal Models for the Development of Cancer Chemoprevention Drugs (2005) (22)
- Pancreatic Cancer Chemoprevention Translational Workshop: Meeting Report (2016) (22)
- Effects of gefitinib (Iressa) on mammary cancers: preventive studies with varied dosages, combinations with vorozole or targretin, and biomarker changes (2008) (22)
- Chemoprevention of rat prostate carcinogenesis by dietary 16alpha-fluoro-5-androsten-17-one (fluasterone), a minimally androgenic analog of dehydroepiandrosterone. (2006) (21)
- Chemoprevention of Urothelial Cell Carcinoma Growth and Invasion by the Dual COX–LOX Inhibitor Licofelone in UPII-SV40T Transgenic Mice (2014) (21)
- Screening of potential cancer preventing chemicals for induction of glutathione in rat liver cells. (1998) (21)
- Preventive Effects of NSAIDs, NO-NSAIDs, and NSAIDs Plus Difluoromethylornithine in a Chemically Induced Urinary Bladder Cancer Model (2013) (20)
- Effects of the farnesyl transferase inhibitor R115777 (Zarnestra) on mammary carcinogenesis: prevention, therapy, and role of HaRas mutations (2006) (19)
- Inhibition of Chemical Carcinogenesis (1995) (18)
- Modulation by licofelone and celecoxib of experimentally induced cancer and preneoplastic lesions in mice exposed to cigarette smoke. (2015) (18)
- Efficacy of chemopreventive agents in mouse mammary gland organ culture (MMOC) model: a comprehensive review. (2008) (18)
- Identification of chemopreventive agents by screening for induction of glutathione-S-transferase as a biomarker (1997) (18)
- In vivo and in vitro characteristics of early carcinogen-induced premalignant phenotypes in cultured rat tracheal epithelial cells. (1988) (18)
- Prevention of mouse lung tumors and modulation of DNA methylation by combined treatment with budesonide and R115777 (ZarnestraMT). (2007) (18)
- Potentiating NK cell activity by combination of Rosuvastatin and Difluoromethylornithine for effective chemopreventive efficacy against Colon Cancer (2016) (18)
- Isolation and long-term culture of rat, rabbit, and human nasal turbinate epithelial cells (1985) (18)
- Effect of reduced body weight gain on the evaluation of chemopreventive agents in the methylnitrosourea-induced mammary cancer model. (1999) (18)
- Null Effect of Dietary Restriction on Prostate Carcinogenesis in the Wistar-Unilever Rat (2007) (17)
- Multitargeted low-dose GLAD combination chemoprevention: a novel and promising approach to combat colon carcinogenesis. (2013) (17)
- The natural history of intraepithelial neoplasia: Relevance to the search for intermediate endpoint biomarkers (1992) (17)
- Modulation by Phenethyl Isothiocyanate and Budesonide of Molecular and Histopathologic Alterations Induced by Environmental Cigarette Smoke in Mice (2009) (17)
- Prevention of methylnitrosourea-induced mammary cancers by 9-cis-retinoic acid and/or vitamin D3. (2002) (16)
- Fixed-Dose Combinations of Pioglitazone and Metformin for Lung Cancer Prevention (2017) (16)
- DNA damage in exfoliated cells and histopathological alterations in the urinary tract of mice exposed to cigarette smoke and treated with chemopreventive agents. (2013) (16)
- Modulation by aspirin and naproxen of nucleotide alterations and tumors in the lung of mice exposed to environmental cigarette smoke since birth. (2015) (16)
- Prevention of mouse lung tumors and modulation of DNA methylation by combined treatment with budesonide and R115777 (Zarnestra MT). (2007) (16)
- Prevention of Chemically Induced Urinary Bladder Cancers by Naproxen: Protocols to Reduce Gastric Toxicity in Humans Do Not Alter Preventive Efficacy (2015) (16)
- Targeting mTOR and p53 Signaling Inhibits Muscle Invasive Bladder Cancer In Vivo (2015) (16)
- Bcl-2 and Bax are differentially expressed in hyperplastic, premalignant, and malignant lesions of mammary carcinogenesis. (2000) (15)
- Clinical Development Plan (2020) (15)
- Suppression of Rat Oral Carcinogenesis by Agonists of Peroxisome Proliferator Activated Receptor γ (2015) (15)
- Correlation between electron-donating ability of a series of 3-nitroflavones and their efficacy to inhibit the onset and progression of aberrant crypt foci in the rat colon. (2002) (15)
- Chemopreventive Effects of an HDAC2-Selective Inhibitor on Rat Colon Carcinogenesis and APCmin/+ Mouse Intestinal Tumorigenesis (2014) (15)
- Chemopreventive Efficacy and Mechanism of Licofelone in a Mouse Lung Tumor Model via Aspiration (2011) (15)
- Simultaneous targeting of 5-LOX-COX and ODC block NNK-induced lung adenoma progression to adenocarcinoma in A/J mice. (2016) (15)
- Assay of lapatinib in murine models of cigarette smoke carcinogenesis. (2014) (15)
- Effect of the aromatase inhibitor vorozole on estrogen and progesterone receptor content of rat mammary carcinomas induced by 1-methyl-1-nitrosourea (2001) (14)
- Clinical development plan: N-Acetyl-l-cysteine. (1994) (14)
- Preclinical Efficacy Studies of Green and Black Tea Extracts (1999) (14)
- Development of Breast Cancer Chemopreventive Drugs (1995) (14)
- Comparative tissue-specific toxicities of 20 cancer preventive agents using cultured cells from 8 different normal human epithelia. (2001) (14)
- Chemopreventive Efficacy of Raloxifene, Bexarotene, and Their Combination on the Progression of Chemically Induced Colon Adenomas to Adenocarcinomas in Rats (2013) (14)
- Clinical development plan: Vitamin E (1994) (13)
- TP53 modulating agent, CP-31398 enhances antitumor effects of ODC inhibitor in mouse model of urinary bladder transitional cell carcinoma. (2015) (13)
- Screening of potential cancer-preventing chemicals for inhibition of induction of ornithine decarboxylase in epithelial cells from rat trachea. (1998) (13)
- The human epithelial cell cytotoxicity assay for determining tissue specific toxicity. (2000) (13)
- Clinical development plan: 2‐Difluoromethylornithine (DFMO) (1994) (13)
- Effects of dietary N-(4-hydroxyphenyl)retinamide on N-nitrosomethylbenzylamine metabolism and esophageal tumorigenesis in the Fischer 344 rat. (2001) (12)
- Neu-induced retroviral rat mammary carcinogenesis: a novel chemoprevention model for both hormonally responsive and nonresponsive mammary carcinomas. (2006) (12)
- Establishment and characterization of sublines of LNCaP human prostate cancer cells. (2003) (12)
- Transformation of rat tracheal epithelial cells by benzo[a]pyrene and its metabolites. (1980) (12)
- Effect of Intermittent Dosing Regimens of Erlotinib on Methylnitrosourea-Induced Mammary Carcinogenesis (2013) (12)
- Blood and lung microRNAs as biomarkers of pulmonary tumorigenesis in cigarette smoke-exposed mice (2016) (12)
- A rat tracheal cell culture transformation system for assessment of environmental agents as carcinogens and promoters (1985) (12)
- Rationale and Approaches to the Prevention of Smoking-Related Diseases: Overview of Recent Studies on Chemoprevention of Smoking-Induced Tumors in Rodent Models (2014) (11)
- Early and late effects of aspirin and naproxen on microRNAs in the lung and blood of mice, either unexposed or exposed to cigarette smoke (2017) (11)
- Safety and Preclinical Efficacy of Aerosol Pioglitazone on Lung Adenoma Prevention in A/J Mice (2016) (11)
- Modulation by budesonide of a CpG endonuclease in mouse lung tumors. (2007) (11)
- Prostate intraepithelial neoplasia in Noble rats, a potential intermediate endpoint for chemoprevention studies. (2004) (11)
- Chemoprevention of mouse lung and colon tumors by suberoylanilide hydroxamic acid and atorvastatin (2012) (10)
- Modulation by bexarotene of mRNA expression of genes in mouse lung tumors (2008) (10)
- Efficacy of the EGFr inhibitor Iressa on development of chemically-induced urinary bladder cancers: dose dependency and modulation of biomarkers. (2011) (10)
- Strategy and planning for chemopreventive drug development: clinical development plans. Chemoprevention Branch and Agent Development Committee. National Cancer Institute. (1994) (9)
- Efficacy of 9-cis-retinoic acid and N-(4-hydroxyphenyl) retinamide alone and in combination in mammary cancer prevention. (2004) (9)
- Selective inhibition by aspirin and naproxen of mainstream cigarette smoke-induced genotoxicity and lung tumors in female mice (2016) (9)
- The human epithelial cell cytotoxicity assay for determining tissue specific toxicity: method modifications. (2002) (9)
- Chemoprevention by difluoromethylornithine: correlation of an in vitro human cell assay with human clinical data for biomarker modulation. (2001) (9)
- Chemopreventive efficacy of Targretin in rodent models of urinary bladder, colon/intestine, head and neck and mammary cancers. (2012) (9)
- Intermittent Dosing Regimens of Aspirin and Naproxen Inhibit Azoxymethane-Induced Colon Adenoma Progression to Adenocarcinoma and Invasive Carcinoma (2019) (9)
- Development and characteristics of a human cell assay for screening agents for melanoma prevention (2007) (9)
- Lack of chemopreventive effects of P2X7R inhibitors against pancreatic cancer (2017) (9)
- Chemoprevention of Lung Carcinogenesis by Dietary Nicotinamide and Inhaled Budesonide (2019) (9)
- Effects of acute and chronic body weight gain reductions in the evaluation of agents for efficacy in mammary cancer prevention. (2001) (8)
- Comparative effects of DHEA and DHT on gene expression in human LNCaP prostate cancer cells. (2006) (8)
- Organ culture-cell culture system for studying multistage carcinogenesis in respiratory epithelium. [Mice] (1977) (8)
- Clinical development plan: Sulindac (1994) (7)
- Interactions between ethanol and cigarette smoke in a mouse lung carcinogenesis model. (2016) (7)
- Screening of potential cancer preventing chemicals as aromatase inhibitors in an in vitro assay. (1999) (7)
- Detection of differentially expressed genes in Methylnitrosourea‐induced rat mammary adenocarcinomas (1997) (7)
- Guidance for development of chemopreventive agents (1994) (7)
- Budesonide and phenethyl isothiocyanate attenuate DNA damage in bronchoalveolar lavage cells of mice exposed to environmental cigarette smoke. (2008) (7)
- Upregulation of stem cell antigen-1 in the lung of neonatal mice exposed to environmental cigarette smoke. (2009) (7)
- Induction of NADPH-quinone reductase as a screening assay for potential chemopreventive agents (1997) (6)
- CANCER CHEMOPREVENTION DRUG DEVELOPMENT STRATEGIES FOR RESVERATROL (1998) (6)
- Daily or weekly dosing with EGFR inhibitors, gefitinib and lapatinib, and AKT inhibitor MK2206 in mammary cancer models (2018) (6)
- Differential growth response to exogenous calcium in normal and carcinogen-exposed primary human keratinocyte cell cultures. (1998) (6)
- Bisphosphonates Zometa and Fosamax Synergize with Metformin to Prevent AOM-Induced Colon Cancer in F344 Rat Model (2019) (6)
- Modulation of Ki67, p53 and RARbeta expression in normal, premalignant and malignant human oral epithelial cells by chemopreventive agents. (2001) (6)
- Tumor promotion studies in rat tracheal epithelium (1983) (6)
- Chemoprevention of Cancer by NSAIDs and Selective COX-2 Blockade (2003) (5)
- Abstract 2839: Licofelone, a novel dual COX-LOX inhibitor prevents progression of PanIN lesions to pancreatic carcinoma by targeting miRNAs and cancer stem cells in p48Cre/+-LSL-KrasG12D/+ transgenic mice (2011) (5)
- Dose-related cytogenetic damage in pulmonary alveolar macrophages from mice exposed to cigarette smoke early in life (2012) (5)
- Effects of celecoxib, polyphenon E and rosiglitazone on hydroxybutyl(butyl)-nitrosamine (OH-BBN) –induced urinary bladder cancers in female Fischer-344 rats. (2004) (5)
- Correlation of in vitro chemopreventive efficacy data from the human epidermal cell assay with animal efficacy data and clinical trial plasma levels (2005) (5)
- Prevention of Familial Adenomatous Polyp Development in APCmin Mice and Azoxymethane-Induced Colon Carcinogenesis in F344 Rats by ω-3 Fatty Acid Rich Perilla Oil (2013) (5)
- 5MeCDDO Blocks Metabolic Activation but not Progression of Breast, Intestine, and Tongue Cancers. Is Antioxidant Response Element a Prevention Target? (2016) (5)
- Screening of Chemopreventive Agents in Animal Models: Results on Reproducibility, Agents of a Given Class, and Agents Tested During Tumor Progression (2018) (5)
- Correlation of chemopreventive efficacy data from the human epidermal cell assay with in vivo data. (2000) (5)
- Clinical development plan: 18beta-glycyrrhetinic acid. (1994) (5)
- Early-Phase Development of Cancer Prevention Agents: Challenges and Opportunities (2013) (5)
- Perspectives on chemoprevention agent selection and short-term clinical prevention trials. (1996) (4)
- A carcinogen-DNA binding assay as a biomarker screen for identifying potential chemopreventive agents (1997) (4)
- Clinical development plan: Tamoxifen (1994) (4)
- Clinical development plan: Oltipraz (1994) (4)
- Chemoprevention of DMBA-induced Mammary Carcinogenesis: Relationship Between Induction of Phase II Enzymes, Effects on DMBA-induced Hemoglobin Adducts and Decreases in Mammary Tumor Multiplicity (2000) (4)
- Prevention of mouse lung tumors and modulation of DNA methylation by combined treatment with budesonide and R115777 (ZarnestraMT). (2007) (4)
- Effect of early vs. late administration of 4‐Hydroxyphenylretinamide (4‐HPR) on N‐Methyl‐N‐Nitrosourea (MNU)‐induced mammary tumorigenesis (1997) (4)
- The human epidermal cell asay for chemopreventive agents (1997) (4)
- Chemoprevention of carcinogen-induced transformation in primary rat tracheal epithelial cells (1997) (4)
- Clinical development plan: Aspirin (1994) (4)
- Clinical development plan: beta-carotene and other carotenoids. (1994) (4)
- Comparison of cadmium cytotoxicity in human versus rat nasal epithelial cells in vitro. (1990) (3)
- Abstract 2268: Metformin prevents progression of pancreatic intraepithelial neoplasia to ductal adenocarcinoma by targeting cancer stem cells and mTOR signaling. (2013) (3)
- Study of Beryllium Oxide Cenotoxicity in Cultured Respiratory Epithelial Cells (1989) (3)
- Predictive Value Tools as an Aid in Chemopreventive Agent Development. (2013) (3)
- Abstract 2820: Omeprazole alone, or in combination with Aspirin inhibits azoxymethane-induced colon adenoma progression to adenocarcinoma and carcinoma invasion in F344 rat model (2015) (3)
- Chemopreventive potential of fumaric acid, N-acetylcysteine, N-(4-hydroxyphenyl) retinamide and β-carotene for tobacco-nitrosamine-induced lung tumors in A/J mice1This is paper 27 in the series `Dietary Inhibitors of Chemical Carcinogenesis'.1 (1998) (3)
- Screening of potential cancer preventing chemicals as antioxidants in an in vitro assay. (1998) (3)
- Clinical development plan: Proscar. (1994) (3)
- Effects of Body Weight Gain Reduction Resulting From Chemopreventive Agent Treatment on Mammary Gland Morphology (2002) (3)
- Lack of chemopreventive activity of lycopene in the Wistar-Unilever rat prostate cancer model (2004) (3)
- The National Cancer Institute's PREVENT Cancer Preclinical Drug Development Program: overview, current projects, animal models, agent development strategies, and molecular targets. (2016) (3)
- Abstract 1005: Targeting COX-LOX and EGFR pathways simultaneously by licofelone and gefitinib lead to complete blockade of progression of PanINs to pancreatic ductal adenocarcinoma (2012) (3)
- Daily or weekly dosing with EGFR inhibitors, gefitinib and lapatinib, and AKT inhibitor MK2206 in mammary cancer models (2018) (3)
- Abstract B42: Lack of chemopreventive effects of metformin in azoxymethane-induced rat colon carcinogenesis (2011) (3)
- Abstract 831: Chemopreventive effects of selective estrogen receptor modulator (SERM) raloxifene on intestinal neoplasia of APCMin/+ mice (2011) (3)
- Perspectives and progress in development of breast cancer chemopreventive drugs. (1997) (3)
- Clinical development plan: Piroxicam (1994) (3)
- Pharmacokinetic and pharmacodynamic study of NO-donating aspirin in F344 rats. (2008) (3)
- Abstract 4983: Intermittent dosing regimens of naproxen and aspirin inhibit azoxymethane-induced rat colon adenoma progression to adenocarcinoma and carcinoma invasion (2018) (3)
- Quantitative morphometry of respiratory tract epithelial cells as a tool for testing chemopreventive agent efficacy. (2010) (3)
- Polyphenols and Cancer Prevention (2001) (2)
- Clinical development plan: Ibuprofen (1994) (2)
- Rationale for the selection and use of in vitro assays to screen for chemopreventive agents (1997) (2)
- Evaluation of Selected Chemopreventive Agents Present in Common Foods in Mouse Mammary Gland Organ Culture (2002) (2)
- Prospects for Chemoprevention of Cancers of the Cervix, Endometrium and Ovary: Surrogate Endpoints and Design of Clinical Trials. Conference proceedings. Oxnard, California, February 1-5, 1995. (1995) (2)
- Symposium : Diet , Natural Products and Cancer Prevention : Progress and Promise Progress in Cancer Chemoprevention : Development of Diet-Derived Chemopreventive Agents 1 (2000) (2)
- Chemoprevention of rat mammary carcinogenesis: Exceptional activity of dietary dehydroepiandrosterone (DHEA) (1993) (2)
- An ornithine decarboxylase activity assay to screen for potential chemopreventive agents (1997) (2)
- Clinical development plan: Calcium (1994) (2)
- Abstract LB-264: Effects of dietary metformin/pioglitazone on lung adenoma formation in A/J mice (2015) (2)
- 4-HYDROXYBUTYL(BUTYL)NITROSAMINE (OH-BBN)- INDUCED URINARY BLADDER CANCERS IN MICE: CHARACTERIZATION OF FHIT, SURVIVIN AND COX-2 EXPRESSION AND CHEMOPREVENTIVE EFFECTS OF INDOMETHACIN (2004) (2)
- Abstract 833: Combination of atorvastatin with sulindac or naproxen profoundly inhibits colonic adenocarcinomas by suppressing the p65/beta-catenin/cyclin D1 signaling pathway in rats (2011) (2)
- Abstract A99: Evaluation of the effects of naproxen in human colon polyp cells using gene expression and pathway analysis (2010) (2)
- Toxicity Profile of Solvents by Aspiration Approach for Topical Agent Delivery to Respiratory Tract Epithelium (2011) (2)
- In vitro chemopreventive efficacy screening using human keratinocytes and the in vivo data correlation. (1999) (2)
- Studies on the action of tumour promoters and antipromoters on respiratory-tract epithelium. (1984) (2)
- Identification of new agents for the prevention of prostate cancer using preclinical animal models (2003) (2)
- Abstract B110: Chemoprevention of rat oral carcinogenesis by licofelone, a dual cyclooxygenase/lipoxygenase inhibitor (2012) (1)
- Response of rosiglitazone, UAB 30, and atorvastatin in the human melanoma prevention assayl. (2006) (1)
- Abstract 821: miRNA profiling and target identification during normal pancreata transformation to PanINs to pancreatic ductal cancer progression in p48Cre/+-LSL-KrasG12D/+ mice: Implication for human pancreatic cancer chemoprevention and treatment (2011) (1)
- Abstract A14: Chemopreventive efficacy of bisphosphonates, Zometa and Fosamax, alone or in combination with metformin in AOM-induced rat colon cancer model (2013) (1)
- Abstract 5260: NGS Transcriptome analysis of colon adenocarcinomas treated with individual and combination of aspirin and omeprazole (2017) (1)
- The Chemopreventive Efficacy of Vandetanib, a Multikinase Inhibitor, in a Primary Respiratory Tract Epithelial Cell Transformation Model (2012) (1)
- The A427 anchorage-independence assay as a screening tool to identify potential chemopreventive agents (1997) (1)
- Preventive effects of the EGFR inhibitor Iressa on chemically-induced urinary bladder cancers: Histopathological and biochemical endpoints (2007) (1)
- Potential Use of Transgenic Mice in Chemoprevention Studies (2005) (1)
- Abstract 186: Clinically relevant low dose combination of rosuvastatin and difluoromethylornithine provides effective chemopreventive efficacy against AOM-induced colon cancers in F344 rats . (2013) (1)
- Abstract 2969: Combinational Targeting of EGFR and ODC pathways by Gefitinib and DFMO lead to complete blockade of PanIN progression to pancreatic ductal adenocarcinoma (2014) (1)
- Prostatitis and Urethritis (1999) (1)
- Proton Pump Inhibitor Omeprazole Suppresses Carcinogen-induced Colonic Adenoma Progression to Adenocarcinoma in F344 Rat (2021) (1)
- ER, RXR, PPAR-γ, HMG-CoA reductase and HDAC as molecular targets for the chemoprevention of colorectal cancer. (2004) (1)
- Abstract 5267: Chemoprevention of lung carcinogenesis by dietary nicotinamide and inhaled budesonide (2017) (1)
- Development of glutathione induction as a screening assay for potential chemopreventive agents (1997) (1)
- Advances in Brief Chemoprevention of Rat Prostate Carcinogenesis by 9-cis-Retinoic Acid 1 (1999) (1)
- Abstract 5241: Nitric oxide-releasing naproxen prevents muscle invasive bladder cancer (2016) (1)
- Use of Druckrey analysis to quantitatively evaluate the chemopreventive efficacy of N-difluoromethylornithine (DFMO), a prototype proliferation inhibitor. (1998) (1)
- Abstract 1858: Inhibition of oral carcinogenesis in rats by the histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA) (2011) (1)
- Abstract 2927: Gefitinib, an EGFR inhibitor, prevents progression of PanINs to pancreatic carcinoma in a preclinical conditionalLSL-K-rasG12Dtransgenic mice model (2010) (1)
- Abstract 2273: Metformin promotes tumorigenesis in animal models of cancer prevention. (2013) (1)
- Clinical development plan: Vitamin D3 and analogs (1994) (1)
- Colony formation enhancement of rat tracheal and nasal epithelial cells by polyacetate, indole alkaloid, and phorbol ester tumor promoters. (1987) (1)
- Abstract 1633: Chemopreventive efficacy of raloxifene, bexarotene and their combination on the progression of AOM-induced colon adenomas to adenocarcinomas in F344 rats (2012) (1)
- Pharmacokinetic and pharmacodynamic study of NO-donating aspirin in F 344 rats (2008) (1)
- Multistage-promotion and carcinogenesis studies in rat tracheal epithelial cells in culture. (1985) (1)
- Abstract 2626: Metabolic profiles and potential pharmacodynamic biomarkers in female Sprague-Dawley rats on a standard (4% fat) or Western (20% fat) diet and treated with known active or inactive chemopreventive agents (2016) (0)
- Abstract A50: Comparative effects of DFMO, sulindac, and DFMO and sulindac on human colon polyp cells determined using pathway analysis (2011) (0)
- Oncogenic Transformation in Epithelial Cell Lines Derived from Trachea! Expiants Exposed in Vitro to /V-Methyl-A/'-mtro-A/-mtrosoguanidme1 (2006) (0)
- Abstract CN08-02: New strategies for cancer chemoprevention (2012) (0)
- Abstract B115: Eflornithine (DFMO) Prevents Progression of Pancreatic Intraepithelial Neoplasia to Ductal Adenocarcinoma in LSL-KrasG12D/+ Mice (2012) (0)
- Abstract A94: Preventive effects of naproxen and NO‐naproxen in carcinogen induced models of urinary bladder, colon, and mammary cancers (2009) (0)
- Abstract 2809: Chemopreventive studies of multiple agents in the methylnitrosourea-induced ER+mammary cancer model in animals on standard and Western diets (2015) (0)
- Epidermal Growth Factor Receptor Inhibitor Gefitinib vents the Progression of Pancreatic Lesions to Carcinoma (2010) (0)
- Abstract 2145: Chemopreventive and immune-modulatory effects of the Cucumaria frondosa extract, Frondanol A5 in the APCMin/+ mice intestinal tumorigenesis (2014) (0)
- Tumor promoting effects of the PPAR gamma agonist rosiglitazone during the progression stages of OH-BBN induced urinary bladder cancer (2007) (0)
- Preventive effects of the RXR agonists targretin and UAB-30 in transgenic mouse models of estrogen receptor (ER) negative mammary cancer (2007) (0)
- Erratum to: Oxidative stress in the lung of mice exposed to cigarette smoke either early in life or in adulthood (2013) (0)
- Histopathology of human intraepithelial neoplasia with implications for chemoprevention strategy. (1993) (0)
- Abstract B114: Next generation whole genome transcriptome SOLiD sequencing analysis of pancreatic ductal adenocarcinoma in LSL-KrasG12D/+ mice (2012) (0)
- Abstract A82: Bardoxolone (5MeCDDO), which induces the antioxidant response element (ARE), is ineffective in inhibiting cancer progression but inhibits cancer initiation in rodent models of cancer. What does it mean for the ARE as a primary prevention target? (2011) (0)
- Abstract A102: Chemopreventive efficacy and mechanistic studies of Targretin in the B[a]P-induced mouse lung tumor prevention model (2010) (0)
- Responses of bromelain in a human cell screening assay for melanoma prevention (2007) (0)
- Abstract 3703: Chemopreventive efficacy of vandetanib, a multikinase inhibitor, in a primary respiratory tract epithelial cell transformation assay (2011) (0)
- Induction of apoptosis by 1,4-phenylenebis seleno-cyanate in cultured human colon cancer cells (1999) (0)
- Chemopreventive effects of Cucumaria frondosa lipid extract in rat colon carcinogenesis and in a human colon cancer cell line (2008) (0)
- Abstract A15: Chemopreventive efficacy of Phospho-Ibuprofen, Rosuvastatin and their combination on AOM-induced colon adenocarcinoma formation in F344 rats (2013) (0)
- Abstract 5246: Effects of bazedoxifene either alone or in combination with letrozole in the prevention of chemically induced mammary cancers (2017) (0)
- Abstract 2625: Simultaneous targeting of ODC and 5-LOX/COX block the tobacco carcinogen-induced lung adenoma progression to adenocarcinoma in A/J mice (2016) (0)
- Bandaru S. Reddy: In Memoriam (1930–2009) (2009) (0)
- Abstract 1849: Chemopreventive efficacy of naproxen, sulindac, and their nitric oxide-derivatives in the hydroxylbutyl(butyl)nitrosamine induced model of urinary bladder cancer (2011) (0)
- Abstract B54: Current intervention strategies in the NCI PREVENT Cancer Preclinical Drug Development Program (2015) (0)
- Possible mechanisms and rankings for agents screened in the Human Cell Melanoma Prevention Assay. (2006) (0)
- Development of Selected Phytochemicals for Cancer Chemoprevention (2004) (0)
- Abstract A101: Dose-related suppression of rat oral carcinogenesis by the EGF receptor-tyrosine kinase inhibitor, gefitinib (2010) (0)
- Abstract B49: Use of MMTV-Neu/P53 KO transgenic mice to screen for potential chemopreventive agents (2010) (0)
- Tissue Sensitivity of Rat Nasal Turbinate Epithelium to CdSO,: Correlation of Tissue Cadmium Levels and Energy Charge (1991) (0)
- Epidermal Growth Factor Receptor Inhibitor Gefitinib vents the Progression of Pancreatic Lesions to Carcinoma Pr R Conditional LSL-KrasG 12 D / + Transgenic Mouse Model (2010) (0)
- PROGRESS IN CANCER CHEMOPREVENTION Inhibit Carcinogen Uptake Inhibit Carcinogen Formation Deactivate Carcinogen Restore Normal Cell Growth / Differentiation Modulate Signal Transduction Pathways Inhibit Poh / amine Metabolism Inhibit Arachidonic (2006) (0)
- Abstract 5065: Pharmacological modulation of inflammation and p53 signaling synergize to prevents muscle invasive bladder cancerin-vivo (2019) (0)
- Effects of talactoferrin alpha on lung adenoma prevention in A/J mice June 2, 2016. (2018) (0)
- 226 Efficacy of cancer preventing drugs administered by intermittent dosing regimens (2014) (0)
- Abstract A106: Efficacy of EGFr inhibitors gefitinib on development of OH-BBN-induced rat bladder tumors: Dose dependency and modulation of biomarkers (2010) (0)
- Caveolin-1 as a target for colon cancer inhibition by lovastatin and celecoxib (2007) (0)
- Advances in Brief Chemoprevention by Lipoxygenase and Leukotriene Pathway Inhibitors of Vinyl Carbamate-induced Lung Tumors in Mice 1 (2002) (0)
- The NCI’s PREVENT Cancer Preclinical Drug Development Program: Overview, Current Projects, Animal Models, Agent Development Strategies, and Molecular Targets (2016) (0)
- TargetingmTORandp53Signaling InhibitsMuscle Invasive Bladder Cancer In Vivo (2015) (0)
- Abstract 5564: Lack of efficacy of metformin in several standard prevention models: Methylnitrosourea rat mammary (ER+), MMTV-Neu/p53 mouse mammary (ER−) and the Min mouse colon (2011) (0)
- Abstract 2819: Targeting inflammation and pancreatitis blocks tumor-initiating stem cells and pancreatic cancer progression (2015) (0)
- Abstract 2135: Chemoprevention of tobacco carcinogen-induced lung cancer by DFMO and Licofelone administered individually or in combination in female A/J mice (2014) (0)
- Abstract PD03-07: Evaluation of the Anti-Diabetic Drug Metformin in the Methylnitrosourea (MNU)-Induced Model of ER+ Mammary Cancer and the MMTV-Neu/p53KO Model of ER-Mammary Cancer (2010) (0)
- 225 Molecular targets of interest to the NCI PREVENT cancer preclinical drug development program (2014) (0)
- Mechanisms Of Inhibition Of Cigarette Smoke Genotoxicity And Carcinogenicity (2010) (0)
- Licorice: Absorption, Distribution, Metabolism and Cancer Chemoprevention (2008) (0)
- Abstract 808: Chemoprevention of colon cancer by DFMO, sulindac and NO-sulindac administered individually or in combinations in male F344 rats (2011) (0)
- Oxidative stress in the lung of mice exposed to cigarette smoke either early in life or in adulthood (2013) (0)
- Comparison of particulate deposition and clearance in mouse lung by two different drug delivery methods (2008) (0)
- Abstract 941: Elucidation of chemopreventive effects of aerosolized rapamycin and dietary myoinositol by mechanistic biomarkers in mouse lung (2010) (0)
- Effect of bexarotene and mushroom extract lsy16 on intestinal neoplasia in the Apc Min/+ mouse model (2006) (0)
- Calcium, Vitamin D, and Prevention of Colon Cancer (2018) (0)
- Abstract 962: Similar preventive effects of naproxen and NO-naproxen in a chemically-induced model of urinary bladder cancer: Dose dependency, gene expression and toxicity (2010) (0)
- P3-10-03: Bardoxolone (5MeCDDO) Inhibits Cancer Initiation but Promotes Progression in Rodent Models of Breast Cancer. What Does It Mean for the Antioxidant Response Element (ARE) as a Primary Prevention Target? (2011) (0)
- Relationship of early, carcinogen-induced, atypical cell colonies to in vivo malignant transformation in the rat tracheal epithelial focus assay (1987) (0)
- Abstract 4653: Modulation of mTOR and p53 signaling using rapamycin plus CP-31398 inhibits growth and progression of urothelial carcinoma in-vivo (2015) (0)
- Vol. 35, 1999 (1999) (0)
- Obituary (1978) (0)
- Development of a human Melanoma prevention assay. (2004) (0)
- Subject Index Vol. 35, 1999 (1999) (0)
- Early biomarkers of response of mammary tumors to preventive/therapeutic agents (2006) (0)
- Efficacy of aerosolized oltipraz in the strain a mouse lung tumor model (2005) (0)
- Abstract A41: Evaluation of maximum tolerated dose of aerosolized Rapamycin in A/J mice (2010) (0)
- Chemoprevention of premalignant and early malignant lesions of the bladder. (1992) (0)
- Abstract 4392: Targeting HADC-2: Chemopreventive effect of OSU-HDAC42 on rat colon carcinogenesis and APCmin/+ Mice intestinal tumorigenesis. (2013) (0)
- Advances in Brief Chemoprevention of Pulmonary Carcinogenesis by Aerosolized Budesonide in Female A / J Mice 1 (2006) (0)
- 222 Estimating predictive values of short-term morphologic assays of cancer chemoprevention for efficacy in animal tumor assays (2014) (0)
- Efficacy of natural antiinflammatories in primary rat tracheal epithelial cell transformation. (2007) (0)
- Animal Symposia (2009) (0)
- Abstract P3-11-04: Metabolic profiles in female Sprague-Dawley rats receiving either a standard (4% fat) or Western (20% fat) diet and changes in rats bearing mammary cancers (2016) (0)
- Modulation of RhoA associated signaling by lovastatin and celecoxib in human colon cancer cells. (2008) (0)
- Abstract A141: Chemopreventive properties of omeprazole against azoxymethane‐induced colonic aberrant crypt foci formation in fats (2010) (0)
- Chemopreventive Effects of an HDAC 2-Selective Inhibitor on Rat Colon Carcinogenesis and APCmin / 1 Mouse Intestinal Tumorigenesis s (2013) (0)
- Biological Activity of Chloropentafluorobenzene (1987) (0)
- Abstract 836: Rexinoids induce cellular senescence in ER-negative breast cancer cells and in MMTV-Neu mammary tumors (2011) (0)
- SHORT REPORT Prevention of mouse lung tumors by targretin (2006) (0)
- Abstract 1244: Licofelone, a dual COX-LOX inhibitor prevents transitional cell carcinoma of urinary bladder in UPII-SV40T transgenic mice (2014) (0)
- Dose-related cytogenetic damage in pulmonary alveolar macrophages from mice exposed to cigarette smoke early in life (2011) (0)
- Preventive Effects of Lapatinib, a Combined EGFR 1 and EGFR 2 Inhibitor, on Methylnitrosourea-Induced ER+ and MMTV-Neu/P53 KO ER- Mammary Cancers. (2009) (0)
- Abstract 837: Reproducibility of efficacy results for chemopreventive agents in the methylnitrosourea-induced rat mammary cancer model (2016) (0)
- Abstract 824: Effects of metfornin on mammary carcinogenesis and metabolic profiles in methylnitrosourea-treated rats on standard or Western diets (2016) (0)
- Abstract B53: Predicting efficacy of chemopreventive agents in animal tumor assays by statistical modeling (2015) (0)
- Abstract B48: Lack of efficacy of the anti-diabetic drug metformin in the ER+ methylnitrosourea (MNU)-induced and the ER- MMTV-Neu/p53KO models of mammary cancer (2010) (0)
- Abstract P5-11-06: Understanding predictive values of short-term morphologic assays of cancer chemoprevention for efficacy in animal mammary gland tumor assays (2015) (0)
- Abstract 5255: Lack of chemopreventive effects of dietary P2×7R inhibitors against pancreatic cancer in p48Cre/+-LSL-KrasG12D/+ mice (2016) (0)
- Abstract 2140: Efficacy of aerosolized pioglitazone in lung carcinogenesis in A/J mice (2014) (0)
- Abstract PR09: Intermittent dosing regimens maintain efficacy of several cancer preventing drugs (2015) (0)
- Abstract A133: Time-dependent gene expression changes in a human colon polyp cell line induced by a clinically relevant concentration of atorvastatin (2008) (0)
- Extrapolation of inhaled particulate toxicity data from experimental animals to humans. Final report (1988) (0)
- Cytotoxicity and Potential Carcinogenicity of Two Anthraquinone Dye Mixtures (1989) (0)
- Abstract 2129: Effects of talactoferrin on lung adenoma prevention in A/J mice (2014) (0)
- Abstract P5-11-01: Correlation of the effects of potential and known chemopreventive agents on proliferation rates in normal mammary glands and mammary cancers with their chemopreventive efficacy (2015) (0)
- Comparative chemopreventive efficacy of Naproxen and NO-Naproxen in rodent models of colon and bladder cancer. (2008) (0)
- Abstract A84: Lack of efficacy of the anti-diabetic drug metformin in the ER+ methylnitrosourea (MNU)-induced and the ER− MMTV-Neu/p53KO models of mammary cancer. (2011) (0)
- Clinical development plan: DHEA analog 8354 (1994) (0)
- Abstract PR02: Combinational targeting of 5-LOX/COX and PI3K/AKT signaling to prevent progression of PanINs to pancreatic ductal adenocarcinoma in p48Cre/+.LSL-KrasG12D/+ mice (2013) (0)
- Erratum to: Oxidative stress in the lung of mice exposed to cigarette smoke either early in life or in adulthood (2013) (0)
- Selective inhibition by aspirin and naproxen of mainstream cigarette smoke-induced genotoxicity and lung tumors in female mice (2015) (0)
- Efficacy of Ethylvanillin in the Prevention of Mammary Tumors Induced by Methylnitrosourea (MNU) in the Rats (1994) (0)
- Abstract 2813: Chemoprevention of mammary cancer: Modeling predictive values of short-term morphologic assays for efficacy in animal tumor assays (2015) (0)
- Prevention of hydroxybutyl(butyl)nitrosamine(OH-BBN)-induced urinary bladder cancer in Fischer-344 rats by cyclooxygenase and lipoxygenase inhibitors. (2006) (0)
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What Schools Are Affiliated With Vernon E. Steele?
Vernon E. Steele is affiliated with the following schools:
