Vicente Felipo
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Vicente Felipo's Degrees
- PhD Biomedical Sciences University of Valencia
- Masters Biochemistry University of Barcelona
- Bachelors Biology University of Valencia
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(Suggest an Edit or Addition)Vicente Felipo's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Neurobiology of ammonia (2002) (583)
- Repeated alcohol administration during adolescence causes changes in the mesolimbic dopaminergic and glutamatergic systems and promotes alcohol intake in the adult rat (2009) (308)
- Value of the critical flicker frequency in patients with minimal hepatic encephalopathy (2007) (302)
- Experimental models of hepatic encephalopathy: ISHEN guidelines (2009) (278)
- Hepatic encephalopathy: effects of liver failure on brain function (2013) (276)
- Hyperammonemia induces neuroinflammation that contributes to cognitive impairment in rats with hepatic encephalopathy. (2010) (271)
- Activation of N‐methyl‐D‐aspartate receptors in rat brain in vivo following acute ammonia intoxication: Characterization by in vivo brain microdialysis (2000) (260)
- Superoxide production and antioxidant enzymes in ammonia intoxication in rats. (1997) (214)
- Acute ammonia toxicity is mediated by the NMDA type of glutamate receptors (1992) (188)
- Brain ATP Depletion Induced by Acute Ammonia Intoxication in Rats Is Mediated by Activation of the NMDA Receptor and Na+, K+‐ATPase (1994) (185)
- Inflammation and hepatic encephalopathy: Ibuprofen restores learning ability in rats with portacaval shunts (2007) (182)
- Chronic hyperammonemia impairs the glutamate–nitric oxide–cyclic GMP pathway in cerebellar neurons in culture and in the rat in vivo (1998) (175)
- Oral administration of sildenafil restores learning ability in rats with hyperammonemia and with portacaval shunts (2005) (170)
- Blocking NMDA receptors prevents the oxidative stress induced by acute ammonia intoxication. (1999) (162)
- Contribution of hyperammonemia and inflammatory factors to cognitive impairment in minimal hepatic encephalopathy (2012) (154)
- Brain edema and inflammatory activation in bile duct ligated rats with diet‐induced hyperammonemia: A model of hepatic encephalopathy in cirrhosis (2006) (148)
- IL-6 and IL-18 in Blood May Discriminate Cirrhotic Patients With and Without Minimal Hepatic Encephalopathy (2009) (148)
- Glutamine synthetase activity and glutamine content in brain: modulation by NMDA receptors and nitric oxide (2003) (147)
- Sources of oxygen radicals in brain in acute ammonia intoxication in vivo (2003) (133)
- Glutamatergic and gabaergic neurotransmission and neuronal circuits in hepatic encephalopathy (2009) (131)
- Chronic Moderate Hyperammonemia Impairs Active and Passive Avoidance Behavior and Conditional Discrimination Learning in Rats (2000) (128)
- Long-Term Potentiation in Hippocampus Involves Sequential Activation of Soluble Guanylate Cyclase, cGMP-Dependent Protein Kinase, and cGMP-Degrading Phosphodiesterase (2002) (112)
- Hyperammonemia increases GABAergic tone in the cerebellum but decreases it in the rat cortex. (2009) (106)
- Restoration of learning ability in hyperammonemic rats by increasing extracellular cGMP in brain (2005) (105)
- Inhibitors of protein kinase C prevent the toxicity of glutamate in primary neuronal cultures (1993) (102)
- NMDA Receptor antagonists prevent acute ammonia toxicity in mice (1996) (102)
- Urea cycle dysregulation in non-alcoholic fatty liver disease. (2018) (101)
- Molecular mechanism of acute ammonia toxicity: role of NMDA receptors (2002) (99)
- Nicotine prevents glutamate-induced proteolysis of the microtubule-associated protein MAP-2 and glutamate neurotoxicity in primary cultures of cerebellar neurons (1998) (95)
- Developmental exposure to polychlorinated biphenyls 52, 138 or 180 affects differentially learning or motor coordination in adult rats. mechanisms involved (2010) (93)
- Glutamate Induces a Calcineurin‐Mediated Dephosphorylation of Na+,K+‐ATPase that Results in Its Activation in Cerebellar Neurons in Culture (1996) (90)
- Hyperammonemia induces glial activation, neuroinflammation and alters neurotransmitter receptors in hippocampus, impairing spatial learning: reversal by sulforaphane (2016) (87)
- A simple animal model of hyperammonemia (1989) (86)
- Effects of Hyperammonemia and Liver Failure on Glutamatergic Neurotransmission (2002) (85)
- Nitroarginine, an Inhibitor of Nitric Oxide Synthase, Prevents Changes in Superoxide Radical and Antioxidant Enzymes Induced by Ammonia Intoxication (1998) (85)
- Long-term ingestion of ammonium increases acetylglutamate and urea levels without affecting the amount of carbamoyl-phosphate synthase. (1988) (83)
- Neuroinflammation increases GABAergic tone and impairs cognitive and motor function in hyperammonemia by increasing GAT-3 membrane expression. Reversal by sulforaphane by promoting M2 polarization of microglia (2016) (81)
- Alteration of mitochondrial calcium homeostasis by ammonia-induced activation of NMDA receptors in rat brain in vivo (2000) (80)
- Brain cholinergic impairment in liver failure (2008) (78)
- Chronic liver failure in rats impairs glutamatergic synaptic transmission and long‐term potentiation in hippocampus and learning ability (2007) (77)
- Patients with minimal hepatic encephalopathy show impaired mismatch negativity correlating with reduced performance in attention tests (2012) (77)
- Region selective alterations of soluble guanylate cyclase content and modulation in brain of cirrhotic patients (2002) (76)
- Ammonia Prevents Activation of NMDA Receptors by Glutamate in Rat Cerebellar Neuronal Cultures (1995) (74)
- Neurotoxicity of ammonia and glutamate: molecular mechanisms and prevention. (1998) (73)
- NMDA receptors in hyperammonemia and hepatic encephalopathy (2007) (72)
- β-Amyloid-induced activation of Caspase-3 in primary cultures of rat neurons (2000) (71)
- Sildenafil citrate improves perinatal outcome in fetuses from pre‐eclamptic rats (2012) (68)
- Activation of NMDA receptors induces protein kinase A‐mediated phosphorylation and degradation of matrin 3. Blocking these effects prevents NMDA‐induced neuronal death (2005) (68)
- Altered content and modulation of soluble guanylate cyclase in the cerebellum of rats with portacaval anastomosis (2001) (68)
- Ammonium Injection Induces an N‐Methyl‐d‐Aspartate Receptor‐Mediated Proteolysis of the Microtubule‐Associated Protein MAP‐2 (1993) (68)
- Mitochondrial dysfunction in acute hyperammonemia (2002) (67)
- Hyperammonemia Impairs NMDA Receptor-Dependent Long-Term Potentiation in the CA1 of Rat Hippocampus In Vitro (2000) (67)
- 3-Nitro-Tyrosine as a Peripheral Biomarker of Minimal Hepatic Encephalopathy in Patients With Liver Cirrhosis (2011) (66)
- Aluminium impairs the glutamate-nitric oxide-cGMP pathway in cultured neurons and in rat brain in vivo: molecular mechanisms and implications for neuropathology. (2001) (66)
- Induction of Rat Brain Tubulin Following Ammonium Ingestion (1988) (66)
- Developmental exposure to polychlorinated biphenyls PCB153 or PCB126 impairs learning ability in young but not in adult rats (2008) (65)
- Nitroarginine, an inhibitor of nitric oxide synthetase, attenuates ammonia toxicity and ammonia-induced alterations in brain metabolism (1995) (64)
- Role of cyclic GMP in glutamate neurotoxicity in primary cultures of cerebellar neurons (1999) (63)
- Serines 890 and 896 of the NMDA receptor subunit NR1 are differentially phosphorylated by protein kinase C isoforms (2005) (63)
- Neuroinflammation contributes to hypokinesia in rats with hepatic encephalopathy: Ibuprofen restores its motor activity (2009) (63)
- Metallothionein‐III Prevents Glutamate and Nitric Oxide Neurotoxicity in Primary Cultures of Cerebellar Neurons (2000) (62)
- Mechanisms of cognitive alterations in hyperammonemia and hepatic encephalopathy: Therapeutical implications (2009) (62)
- Carnitine and choline derivatives containing a trimethylamine group prevent ammonia toxicity in mice and glutamate toxicity in primary cultures of neurons. (1996) (61)
- Modulation of NMDA receptors in the cerebellum. 1. Properties of the NMDA receptor that modulate its function (2008) (61)
- Reducing Peripheral Inflammation with Infliximab Reduces Neuroinflammation and Improves Cognition in Rats with Hepatic Encephalopathy (2016) (61)
- Chronic hyperammonemia induces peripheral inflammation that leads to cognitive impairment in rats: reversal by anti-tnfa treatment. (2020) (60)
- Brain region-selective mechanisms contribute to the progression of cerebral alterations in acute liver failure in rats. (2011) (59)
- Role of NMDA receptors in acute liver failure and ammonia toxicity: Therapeutical implications (2009) (57)
- p38 MAP kinase is a therapeutic target for hepatic encephalopathy in rats with portacaval shunts (2011) (57)
- Prenatal Exposure to Aluminum Reduces Expression of Neuronal Nitric Oxide Synthase and of Soluble Guanylate Cyclase and Impairs Glutamatergic Neurotransmission in Rat Cerebellum (1999) (56)
- Downregulation of nNOS and synthesis of PGs associated with endotoxin-induced delay in gastric emptying. (2002) (56)
- Gender differences in spatial learning, synaptic activity, and long-term potentiation in the hippocampus in rats: molecular mechanisms. (2015) (54)
- Sildenafil reduces neuroinflammation and restores spatial learning in rats with hepatic encephalopathy: underlying mechanisms (2015) (54)
- Chronic Exposure to Aluminum Impairs Neuronal Glutamate‐Nitric Oxide‐Cyclic GMP Pathway (1998) (53)
- Chronic hyperammonemia reduces the activity of neuronal nitric oxide synthase in cerebellum by altering its localization and increasing its phosphorylation by calcium‐calmodulin kinase II (2008) (53)
- Lack of correlation between glutamate-induced depletion of ATP and neuronal death in primary cultures of cerebellum (1995) (53)
- Chronic hyperammonemia prevents changes in brain energy and ammonia metabolites induced by acute ammonium intoxication. (1993) (53)
- Hypolocomotion in rats with chronic liver failure is due to increased glutamate and activation of metabotropic glutamate receptors in substantia nigra. (2007) (52)
- Serum metabolic signature of minimal hepatic encephalopathy by (1)H-nuclear magnetic resonance. (2010) (49)
- Inhibition of protein kinase C induces differentiation in Neuro-2a cells. (1990) (49)
- Developmental exposure to polychlorinated biphenyls or methylmercury, but not to its combination, impairs the glutamate–nitric oxide–cyclic GMP pathway and learning in 3-month-old rats (2008) (48)
- Differential long-term effects of developmental exposure to polychlorinated biphenyls 52, 138 or 180 on motor activity and neurotransmission. Gender dependence and mechanisms involved (2011) (48)
- GR3027 antagonizes GABAA receptor-potentiating neurosteroids and restores spatial learning and motor coordination in rats with chronic hyperammonemia and hepatic encephalopathy (2015) (48)
- Peripheral inflammation induces neuroinflammation that alters neurotransmission and cognitive and motor function in hepatic encephalopathy: Underlying mechanisms and therapeutic implications (2019) (48)
- Limited Capacity for Ammonia Removal by Brain in Chronic Liver Failure: Potential Role of Nitric Oxide (2005) (47)
- Inhibition of Protein Kinase C Restores Na+, K+‐ATPase Activity in Sciatic Nerve of Diabetic Mice (1992) (47)
- A specific inhibitor of protein kinase C induces differentiation of neuroblastoma cells. (1990) (47)
- Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy (2016) (47)
- Pregnenolone sulfate restores the glutamate-nitric-oxide-cGMP pathway and extracellular GABA in cerebellum and learning and motor coordination in hyperammonemic rats. (2014) (47)
- [Normality tables in the Spanish population for psychometric tests used in the diagnosis of minimal hepatic encephalopathy]. (2006) (45)
- Chronic hyperammonemia alters motor and neurochemical responses to activation of group i metabotropic glutamate receptors in the nucleus accumbens in rats in vivo (2003) (44)
- Sustained Recovery of Na+-K+-ATPase Activity in Sciatic Nerve of Diabetic Mice by Administration of H7 or Calphostin C, Inhibitors of PKC (1993) (44)
- Effects of acute hyperammonemia in vivo on oxidative metabolism in nonsynaptic rat brain mitochondria. (1997) (43)
- Acute liver failure-induced death of rats is delayed or prevented by blocking NMDA receptors in brain. (2008) (43)
- Alcohol exposure during brain development reduces 3H-MK-801 binding and enhances metabotropic-glutamate receptor-stimulated phosphoinositide hydrolysis in rat hippocampus. (1995) (42)
- Modulation of NMDA receptors in the cerebellum. II. Signaling pathways and physiological modulators regulating NMDA receptor function (2008) (41)
- Changes in liver and plasma acetylcholinesterase in rats with cirrhosis induced by bile duct ligation (2006) (41)
- The function of the glutamate-nitric oxide-cGMP pathway in brain in vivo and learning ability decrease in parallel in mature compared with young rats. (2007) (41)
- Magnetic resonance analysis of the effects of acute ammonia intoxication on rat brain. Role of NMDA receptors (2007) (40)
- Ebselen prevents chronic alcohol-induced rat hippocampal stress and functional impairment. (2007) (40)
- Interplay between glutamatergic and GABAergic neurotransmission alterations in cognitive and motor impairment in minimal hepatic encephalopathy (2015) (39)
- Glutamate‐induced activation of nitric oxide synthase is impaired in cerebral cortex in vivo in rats with chronic liver failure (2007) (39)
- Ultrasound bioeffects in rats: quantification of cellular damage in the fetal liver after pulsed Doppler imaging (2011) (39)
- Proteome analysis of primary neurons and astrocytes from rat cerebellum. (2005) (39)
- Motor activity is modulated via different neuronal circuits in rats with chronic liver failure than in normal rats (2007) (38)
- Chronic exposure to aluminium impairs the glutamate-nitric oxide-cyclic GMP pathway in the rat in vivo (1999) (37)
- Cyclic GMP pathways in hepatic encephalopathy. Neurological and therapeutic implications (2010) (37)
- Acute ammonia intoxication induces an NMDA receptor‐mediated increase in poly(ADP‐ribose) polymerase level and NAD+ metabolism in nuclei of rat brain cells (2004) (37)
- Inhibition of protein kinase C induces differentiation of neuroblastoma cells (1989) (37)
- Expression and traffic of cellular prolyl oligopeptidase are regulated during cerebellar granule cell differentiation, maturation, and aging (2008) (36)
- A novel N-methyl-D-aspartate receptor open channel blocker with in vivo neuroprotectant activity. (2002) (36)
- Sildenafil reduces neuroinflammation in cerebellum, restores GABAergic tone, and improves motor in‐coordination in rats with hepatic encephalopathy (2017) (36)
- Polychlorinated biphenyls PCB 52, PCB 180, and PCB 138 impair the glutamate-nitric oxide-cGMP pathway in cerebellar neurons in culture by different mechanisms. (2010) (36)
- Control of brain glutamine synthesis by NMDA receptors. (2007) (36)
- Modulation of Glutamine Synthesis in Cultured Astrocytes by Nitric Oxide (1997) (35)
- Hyperammonemia decreases protein-kinase-C-dependent phosphorylation of microtubule-associated protein 2 and increases its binding to tubulin. (1993) (35)
- Molecular mechanism of acute ammonia toxicity and of its prevention by L-carnitine. (1994) (35)
- Increasing the function of the glutamate‐nitric oxide‐cyclic guanosine monophosphate pathway increases the ability to learn a Y‐maze task (2009) (34)
- Focal cortical damage parallels cognitive impairment in minimal hepatic encephalopathy (2012) (34)
- Non invasive blood flow measurement in cerebellum detects minimal hepatic encephalopathy earlier than psychometric tests. (2014) (33)
- Sequential activation of soluble guanylate cyclase, protein kinase G and cGMP-degrading phosphodiesterase is necessary for proper induction of long-term potentiation in CA1 of hippocampus Alterations in hyperammonemia (2004) (33)
- Potentiation of the Transient Receptor Potential Vanilloid 1 Channel Contributes to Pruritogenesis in a Rat Model of Liver Disease* (2013) (32)
- Extracellular cGMP Modulates Learning Biphasically by Modulating Glycine Receptors, CaMKII and Glutamate-Nitric Oxide-cGMP Pathway (2016) (32)
- cGMP modulates stem cells differentiation to neurons in brain in vivo (2010) (32)
- The Cerebellum of Patients with Steatohepatitis Shows Lymphocyte Infiltration, Microglial Activation and Loss of Purkinje and Granular Neurons (2018) (32)
- Gender differential effects of developmental exposure to methyl-mercury, polychlorinated biphenyls 126 or 153, or its combinations on motor activity and coordination. (2013) (31)
- Activation of the metabotropic glutamate receptor mGluR5 prevents glutamate toxicity in primary cultures of cerebellar neurons. (1997) (31)
- Prenatal exposure to polybrominated diphenylether 99 enhances the function of the glutamate–nitric oxide–cGMP pathway in brain in vivo and in cultured neurons (2007) (31)
- Cerebral oedema is not responsible for motor or cognitive deficits in rats with hepatic encephalopathy (2014) (30)
- Hyperammonemia impairs long-term potentiation in hippocampus by altering the modulation of cGMP-degrading phosphodiesterase by protein kinase G (2004) (30)
- The PHES battery does not detect all cirrhotic patients with early neurological deficits, which are different in different patients (2017) (30)
- Increasing extracellular cGMP in cerebellum in vivo reduces neuroinflammation, GABAergic tone and motor in-coordination in hyperammonemic rats (2017) (30)
- Effects of acute hyperammonemiain Vivo on oxidative metabolism in nonsynaptic rat brain mitochondria (1997) (30)
- Neurons exposed to ammonia reproduce the differential alteration in nitric oxide modulation of guanylate cyclase in the cerebellum and cortex of patients with liver cirrhosis (2005) (30)
- Hyperammonaemia alters the mechanisms by which metabotropic glutamate receptors in nucleus accumbens modulate motor function (2007) (30)
- Bile duct ligation plus hyperammonemia in rats reproduces the alterations in the modulation of soluble guanylate cyclase by nitric oxide in brain of cirrhotic patients (2005) (29)
- Contribution of altered signal transduction associated to glutamate receptors in brain to the neurological alterations of hepatic encephalopathy. (2006) (29)
- Animal Models in the Study of Episodic Hepatic Encephalopathy in Cirrhosis (2005) (29)
- Chronic hyperammonemia, glutamatergic neurotransmission and neurological alterations (2013) (29)
- In vivo administration of extracellular cGMP normalizes TNF-α and membrane expression of AMPA receptors in hippocampus and spatial reference memory but not IL-1β, NMDA receptors in membrane and working memory in hyperammonemic rats (2016) (28)
- L-Carnitine increases the affinity of glutamate for quisqualate receptors and prevents glutamate neurotoxicity (1994) (28)
- Encapsulation of glutamine synthetase in mouse erythrocytes: a new procedure for ammonia detoxification. (2008) (28)
- Developmental Exposure to Pesticides Alters Motor Activity and Coordination in Rats: Sex Differences and Underlying Mechanisms (2018) (28)
- Phosphate-activated glutaminase activity is enhanced in brain, intestine and kidneys of rats following portacaval anastomosis. (2006) (28)
- Serum nitrotyrosine and psychometric tests as indicators of impaired fitness to drive in cirrhotic patients with minimal hepatic encephalopathy (2013) (28)
- Chronic hyperammonemia induces tonic activation of NMDA receptors in cerebellum (2010) (28)
- Role of extracellular cGMP and of hyperammonemia in the impairment of learning in rats with chronic hepatic failure Therapeutic implications (2006) (28)
- Prevention of Ammonia and Glutamate Neurotoxicity by Carnitine: Molecular Mechanisms (2002) (28)
- Sex-dependent effects of developmental exposure to different pesticides on spatial learning. The role of induced neuroinflammation in the hippocampus. (2017) (28)
- Insight into the neuroproteomics effects of the food-contaminant non-dioxin like polychlorinated biphenyls. (2012) (28)
- Prevention of in vivo excitotoxicity by a family of trialkylglycines, a novel class of neuroprotectants. (2002) (28)
- Altered postural control and stability in cirrhotic patients with minimal hepatic encephalopathy correlate with cognitive deficits (2017) (27)
- Learning and Memory Impairments in Patients with Minimal Hepatic Encephalopathy are Associated with Structural and Functional Connectivity Alterations in Hippocampus (2018) (27)
- New Trends in Cancer for the 21st Century (2003) (27)
- High Ammonia Levels in Brain Induce Tubulin in Cerebrum but Not in Cerebellum (1988) (27)
- Modulation of NMDA receptors by AKT kinase (2006) (27)
- Chronic Exposure to Ammonia Alters Pathways Modulating Phosphorylation of Microtubule‐Associated Protein 2 in Cerebellar Neurons in Culture (1999) (27)
- Protective effect of long term ammonium ingestion against acute ammonium intoxication. (1988) (27)
- NMDA‐induced phosphorylation of the microtubule‐associated protein MAP‐2 is mediated by activation of nitric oxide synthase and MAP kinase (2001) (26)
- Modulation of NMDA receptor function by cyclic AMP in cerebellar neurones in culture (2004) (25)
- Brain regional alterations in the modulation of the glutamate–nitric oxide-cGMP pathway in liver cirrhosis Role of hyperammonemia and cell types involved (2006) (25)
- Minimal hepatic encephalopathy is associated with expansion and activation of CD4+CD28−, Th22 and Tfh and B lymphocytes (2017) (25)
- Glutamate and muscarinic receptors in the molecular mechanisms of acute ammonia toxicity and of its prevention. (1997) (24)
- Chronic exposure to ammonia induces isoform‐selective alterations in the intracellular distribution and NMDA receptor‐mediated translocation of protein kinase C in cerebellar neurons in culture (2005) (24)
- Synthesis of new 2-arylamino-6-trifluoromethylpyridine-3-carboxylic acid derivatives and investigation of their analgesic activity. (2004) (24)
- Control of urea synthesis and ammonia utilization in protein deprivation and refeeding. (1991) (24)
- Molecular Mechanisms of the Alterations in NMDA Receptor-Dependent Long-Term Potentiation in Hyperammonemia (2005) (24)
- Acute ammonia neurotoxicity in vivo involves increase in cytoplasmic protein P53 without alterations in other markers of apoptosis (2007) (24)
- Treatment with sildenafil prevents impairment of learning in rats born to pre-eclamptic mothers (2010) (24)
- Chronic hyperammonemia alters the circadian rhythms of corticosteroid hormone levels and of motor activity in rats (2009) (23)
- Activation of soluble guanylate cyclase by nitric oxide in lymphocytes correlates with minimal hepatic encephalopathy in cirrhotic patients (2007) (23)
- Alterations in soluble guanylate cyclase content and modulation by nitric oxide in liver disease (2004) (23)
- Correlation of nitric oxide and atrial natriuretic peptide changes with altered cGMP homeostasis in liver cirrhosis (2005) (23)
- Hippocampal long-term potentiation is reduced in mature compared to young male rats but not in female rats (2007) (23)
- Progressive reduction of sleep time and quality in rats with hepatic encephalopathy caused by portacaval shunts (2012) (23)
- Polychlorinated Biphenyls PCB 153 and PCB 126 Impair the Glutamate–Nitric Oxide–cGMP Pathway in Cerebellar Neurons in Culture by Different Mechanisms (2009) (22)
- Role of nitric oxide and cyclic GMP in glutamate-induced neuronal death (2001) (22)
- The expression levels of prolyl oligopeptidase responds not only to neuroinflammation but also to systemic inflammation upon liver failure in rat models and cirrhotic patients (2015) (22)
- Chronic hyperammonemia alters extracellular glutamate, glutamine and GABA and membrane expression of their transporters in rat cerebellum. Modulation by extracellular cGMP (2019) (21)
- Chronic hyperammonemia in vivo impairs long‐term potentiation in hippocampus by altering activation of cyclic GMP‐dependent‐protein kinase and of phosphodiesterase 5 (2005) (21)
- The expression of nNOS, iNOS and nitrotyrosine is increased in the rat cerebral cortex in experimental hepatic encephalopathy (2006) (21)
- Differential effects of acute and chronic hyperammonemia on signal transduction pathways associated to NMDA receptors (2000) (21)
- Histological Features of Cerebellar Neuropathology in Patients With Alcoholic and Nonalcoholic Steatohepatitis (2018) (20)
- Inhibition of protein kinase C arrests proliferation of human tumors (1991) (20)
- Mutagenicity of nitric oxide-releasing compounds in Escherichia coli: effect of superoxide generation and evidence for two mutagenic mechanisms. (2001) (20)
- Neuroinflammation and neurological alterations in chronic liver diseases (2015) (20)
- Sustained hyperammonemia induces TNF-a IN Purkinje neurons by activating the TNFR1-NF-κB pathway (2020) (19)
- Bicuculline Reduces Neuroinflammation in Hippocampus and Improves Spatial Learning and Anxiety in Hyperammonemic Rats. Role of Glutamate Receptors (2019) (19)
- Differential modulation of the glutamate-nitric oxide-cyclic GMP pathway by distinct neurosteroids in cerebellum in vivo (2011) (19)
- Treatment of hyperammonemia with carbamylglutamate in rats (1992) (19)
- An Inhibitor of Neuronal Exocytosis (DD04107) Displays Long-Lasting In Vivo Activity against Chronic Inflammatory and Neuropathic Pain (2012) (19)
- Haemodynamic effects of long‐term administration of sildenafil in normotensive pregnant and non‐pregnant rats (2011) (18)
- Hyperammonemia alters membrane expression of GluA1 and GluA2 subunits of AMPA receptors in hippocampus by enhancing activation of the IL-1 receptor: underlying mechanisms (2018) (18)
- Is cognitive impairment in cirrhotic patients due to increased peroxynitrite and oxidative stress? (2015) (18)
- Roles of the NMDA Receptor and EAAC1 Transporter in the Modulation of Extracellular Glutamate by Low and High Affinity AMPA Receptors in the Cerebellum in Vivo: Differential Alteration in Chronic Hyperammonemia. (2015) (18)
- Hyperammonemia alters the modulation by different neurosteroids of the glutamate–nitric oxide–cyclic GMP pathway through NMDA‐ GABAA‐ or sigma receptors in cerebellum in vivo (2013) (18)
- Neuronal and inducible nitric oxide synthase expression in the rat cerebellum following portacaval anastomosis (2005) (18)
- Extracellular Vesicles from Hyperammonemic Rats Induce Neuroinflammation and Motor Incoordination in Control Rats (2020) (18)
- Inhibitors of phospholipase C prevent glutamate neurotoxicity in primary cultures of cerebellar neurons. (2000) (18)
- Prevention of glutamate neurotoxicity in cultured neurons by 3,4-dihydro-6-hydroxy-7-methoxy-2,2-dimethyl-1(2H)-benzopyran (CR-6), a scavenger of nitric oxide. (1999) (17)
- Inhibition of γ-Secretase Leads to an Increase in Presenilin-1 (2017) (17)
- Preparation and handling of brain mitochondria useful to study uptake and release of calcium. (2001) (17)
- Determination of intracellular ATP in primary cultures of neurons. (1997) (17)
- Alterations in adipocytokines and cGMP homeostasis in morbid obesity patients reverse after bariatric surgery (2013) (17)
- Differential effects of chronic hyperammonemia on modulation of the glutamate–nitric oxide–cGMP pathway by metabotropic glutamate receptor 5 and low and high affinity AMPA receptors in cerebellum in vivo (2012) (17)
- Metabotropic glutamate receptor 5 modulates the nitric oxide-cGMP pathway in cerebellum in vivo through activation of AMPA receptors (2011) (17)
- 239 BRAIN REGION SELECTIVE MECHANISMS CONTRIBUTE TO THE PROGRESSION OF CEREBRAL ALTERATIONS IN ACUTE LIVER FAILURE IN RATS (2012) (17)
- Long-term potentiation in hippocampus involves sequential activation of soluble guanylate cyclase, cGMP-dependent protein kinase and cGMP-degrading phosphodiesterase, alterations in hyperammonemia (2005) (17)
- Cerebellum proteomics addressing the cognitive deficit of rats perinatally exposed to the food-relevant polychlorinated biphenyl 138. (2011) (17)
- Blocking NMDA Receptors Delays Death in Rats with Acute Liver Failure by Dual Protective Mechanisms in Kidney and Brain (2014) (16)
- Chronic hyperammonemia in rats impairs activation of soluble guanylate cyclase in neurons and in lymphocytes: a putative peripheral marker for neurological alterations. (1999) (16)
- Amyloid-β impairs, and ibuprofen restores, the cGMP pathway, synaptic expression of AMPA receptors and long-term potentiation in the hippocampus. (2010) (16)
- In vivo exposure to carbon monoxide causes delayed impairment of activation of soluble guanylate cyclase by nitric oxide in rat brain cortex and cerebellum (2004) (16)
- Advances in Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy (2012) (16)
- Ammonium ingestion prevents depletion of hepatic energy metabolites induced by acute ammonium intoxication. (1991) (16)
- Hyperammonemia inhibits the natriuretic peptide receptor 2 (NPR-2)-mediated cyclic GMP synthesis in the astrocytic compartment of rat cerebral cortex slices. (2007) (16)
- Ammonia prevents glutamate-induced but not low K+-induced apoptosis in cerebellar neurons in culture (2003) (16)
- Reduced resting state connectivity and gray matter volume correlate with cognitive impairment in minimal hepatic encephalopathy (2017) (16)
- Endosulfan and Cypermethrin Pesticide Mixture Induces Synergistic or Antagonistic Effects on Developmental Exposed Rats Depending on the Analyzed Behavioral or Neurochemical End Points. (2017) (15)
- Blocking glycine receptors reduces neuroinflammation and restores neurotransmission in cerebellum through ADAM17-TNFR1-NF-κβ pathway (2020) (14)
- Chronic exposure to ammonia alters the modulation of phosphorylation of microtubule-associated protein 2 by metabotropic glutamate receptors 1 and 5 in cerebellar neurons in culture (2005) (14)
- Carnitine prevents NMDA receptor-mediated activation of MAP-kinase and phosphorylation of microtubule-associated protein 2 in cerebellar neurons in culture (2002) (14)
- Chronic exposure to ammonia alters basal and NMDA-induced phosphorylation of NMDA receptor-subunit NR1 (2006) (14)
- Altered modulation of soluble guanylate cyclase in lymphocytes from patients with liver disease (2002) (14)
- Hepatic encephalopathy (2022) (14)
- Activation of soluble guanylate cyclase by nitric oxide in lymphocytes correlates with minimal hepatic encephalopathy in cirrhotic patients (2007) (13)
- Reduced white matter microstructural integrity correlates with cognitive deficits in minimal hepatic encephalopathy (2013) (13)
- Differential effects of the protein kinase C inhibitors H7 and calphostin C on the cell cycle of neuroblastoma cells (1992) (13)
- Impaired release of corticosterone from adrenals contributes to impairment of circadian rhythms of activity in hyperammonemic rats. (2013) (13)
- Diet induced hyperammonemia decreases neuronal nuclear size in rat entorhinal cortex (1997) (13)
- High ammonia levels decrease brain acetylcholinesterase activity both in vivo and in vitro. (1994) (13)
- Hepatic Encephalopathy, Hyperammonemia, and Ammonia Toxicity (2012) (13)
- Role of NMDA and AMPA glutamatergic receptors in the effects of social defeat on the rewarding properties of MDMA in mice (2018) (13)
- Altered Modulation of Soluble Guanylate Cyclase by Nitric Oxide in Patients with Liver Disease (2002) (13)
- The precursor of rat liver mitochondrial glutamate dehydrogenase has enzymatic activity. (1983) (13)
- Motor and Cognitive Performance in Patients with Liver Cirrhosis with Minimal Hepatic Encephalopathy (2020) (13)
- Cell-free synthesis and processing of a large precursor of glutamate dehydrogenase of rat liver. (1982) (13)
- Chronic hyperammonemia alters protein phosphorylation and glutamate receptor-associated signal transduction in brain (2002) (13)
- Neurochemistry of ammonia (2002) (13)
- Metabotropic glutamate receptor 5, but not 1, modulates NMDA receptor-mediated activation of neuronal nitric oxide synthase (2010) (12)
- Differential role of interleukin‐1β in neuroinflammation‐induced impairment of spatial and nonspatial memory in hyperammonemic rats (2019) (12)
- Tadalafil Treatment Improves Inflammation, Cognitive Function, And Mismatch Negativity Of Patients With Low Urinary Tract Symptoms And Erectile Dysfunction (2019) (12)
- Selective improvement by rifaximin of changes in the immunophenotype in patients who improve minimal hepatic encephalopathy (2019) (12)
- Real‐time cytometric assay of nitric oxide and superoxide interaction in peripheral blood monocytes: A no‐wash, no‐lyse kinetic method (2017) (11)
- Transport and regulation of polypeptide precursors of mature mitochondrial proteins. (1984) (11)
- Chronic exposure to 2,5-hexanedione impairs the glutamate-nitric oxide-cyclic GMP pathway in cerebellar neurons in culture and in rat brain in vivo (2003) (11)
- Exit of proteins and fragments thereof from mitochondria is accelerated by the import of cytosolic synthesized proteins. (1983) (11)
- Hyperammonemia decreases body fat content in rat (1989) (11)
- Activation of NMDA receptor mediates the toxicity of ammonia and the effects of ammonia on the microtubule-associated protein MAP-2. (1993) (11)
- Early spatial memory deficit induced by 2,5-hexanedione in the rat. (2002) (11)
- Cirrhosis, Hepatic Encephalopathy, and Ammonium Toxicity (1990) (11)
- Bacteroides uniformis CECT 7771 Modulates the Brain Reward Response to Reduce Binge Eating and Anxiety-Like Behavior in Rat (2021) (11)
- Rats with Mild Bile Duct Ligation Show Hepatic Encephalopathy with Cognitive and Motor Impairment in the Absence of Cirrhosis: Effects of Alcohol Ingestion (2015) (11)
- Mass Spectrometrical Analysis of Galectin Proteins in Primary Rat Cerebellar Astrocytes (2006) (10)
- Hyperammonemia alters glycinergic neurotransmission and modulation of the glutamate‐nitric oxide‐cGMP pathway by extracellular glycine in cerebellum in vivo (2016) (10)
- The Dual Role of the GABAA Receptor in Peripheral Inflammation and Neuroinflammation: A Study in Hyperammonemic Rats (2021) (10)
- Activation of soluble guanylate cyclase by nitric oxide is increased in lymphocytes from both rats chronically exposed to 2,5-hexanedione and workers chronically exposed to n-hexane. (2007) (9)
- Extracellular Protein Kinase A Modulates Intracellular Calcium/Calmodulin-Dependent Protein Kinase II, Nitric Oxide Synthase, and the Glutamate-Nitric Oxide-cGMP Pathway in Cerebellum. Differential Effects in Hyperammonemia. (2016) (9)
- Prevention of the acute neurotoxic effects of phenytoin on rat peripheral nerve by H7, an inhibitor of protein kinase C. (1992) (9)
- Altered Modulation of Motor Activity by Group I Metabotropic Glutamate Receptors in the Nucleus Accumbens in Hyperammonemic Rats (2005) (9)
- Increased protein kinase A regulatory subunit content and cGMP binding in erythrocyte membranes in liver cirrhosis. (2004) (9)
- Effects of hyperammonemia on brain protein kinase C substrates (1996) (9)
- Rats with minimal hepatic encephalopathy due to portacaval shunt show differential increase of translocator protein (18 kDa) binding in different brain areas, which is not affected by chronic MAP-kinase p38 inhibition (2014) (9)
- A New Score Unveils a High Prevalence of Mild Cognitive Impairment in Patients with Nonalcoholic Fatty Liver Disease (2021) (8)
- Chronic hyperammonemia alters in opposite ways membrane expression of GluA1 and GluA2 AMPA receptor subunits in cerebellum. Molecular mechanisms involved. (2018) (8)
- Paradoxical protection of both protein-free and high protein diets against acute ammonium intoxication. (1988) (8)
- H7, an inhibitor of protein kinase C, prevents serum-induced phosphorylation of Raf and MAP kinase in neuroblastoma cells (1996) (8)
- Sildenafil reduces neuroinflammation and restores spatial learning in rats with hepatic encephalopathy: underlying mechanisms (2015) (8)
- Extracellular Cyclic GMP Modulates Membrane Expression of The GluA1 and GluA2 Subunits of AMPA Receptor in Cerebellum: Molecular Mechanisms Involved (2017) (7)
- The effects of hyperammonemia in learning and brain metabolic activity (2014) (7)
- The S1PR2‐CCL2‐BDNF‐TrkB pathway mediates neuroinflammation and motor incoordination in hyperammonaemia (2022) (7)
- A single transient episode of hyperammonemia induces long-lasting alterations in protein kinase A. (2007) (7)
- Selective regional distribution of tubulin induced in cerebrum by hyperammonemia (1989) (7)
- Modulation of GABAA receptors by neurosteroids. A new concept to improve cognitive and motor alterations in hepatic encephalopathy (2016) (7)
- Exploratory investigation on nitro- and phospho-proteome cerebellum changes in hyperammonemia and hepatic encephalopathy rat models (2012) (7)
- Adenosine 5'‐triphosphate stimulates the release of polypeptides from mitochondria (1985) (6)
- Blockade of nitric oxide signalling promotes resilience to the effects of social defeat stress on the conditioned rewarding properties of MDMA in mice. (2020) (6)
- Rifaximin Prevents T-Lymphocytes and Macrophages Infiltration in Cerebellum and Restores Motor Incoordination in Rats with Mild Liver Damage (2021) (6)
- H7, a protein kinase C inhibitor, increases the glutathione content of neuroblastoma cells (1992) (6)
- Multi-omic analysis unveils biological pathways in peripheral immune system associated to minimal hepatic encephalopathy appearance in cirrhotic patients (2021) (6)
- Presence of diadenosine polyphosphates in microdialysis samples from rat cerebellum in vivo: effect of mild hyperammonemia on their receptors (2013) (6)
- Transport of AMPA receptors during long-term potentiation is impaired in rats with hepatic encephalopathy (2009) (6)
- Rats with minimal hepatic encephalopathy show reduced cGMP-dependent protein kinase activity in hypothalamus correlating with circadian rhythms alterations (2015) (6)
- Assembly and disassembly of brain tubulin is affected by high ammonia levels (1989) (6)
- Protein kinase C isoforms and cell proliferation in neuroblastoma cells. (1996) (6)
- Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy (1993) (6)
- Pharmacological manipulation of cyclic GMP levels in brain restores learning ability in animal models of hepatic encephalopathy: therapeutic implications (2006) (6)
- Rats that consume caffeine show decreased brain protein synthesis (2004) (5)
- Extracellular Vesicles From Hyperammonemic Rats Induce Neuroinflammation in Cerebellum of Normal Rats: Role of Increased TNFα Content (2022) (5)
- Perinatal exposure to purity-controlled polychlorinated biphenyl 52, 138, or 180 alters toxicogenomic profiles in peripheral blood of rats after 4 months. (2013) (5)
- Precursors of mitochondrial proteins are degraded in the cytosol at different rates (1986) (5)
- Actinomycin D decreases protein kinase C content and induces neuritogenesis in neuroblastoma cells (1991) (5)
- Hyperammonemia induces polymerization of brain tubulin (1990) (5)
- Lymphocyte cytochrome c oxidase, cyclic GMP and cholinergic muscarinic receptors as peripheral indicators of carbon monoxide neurotoxicity after acute and repeated exposure in the rat. (2006) (5)
- 5'-adenosine monophosphate inhibits ternary complex formation by rat liver eIF-2. (1987) (5)
- Inhibition of proliferation of primary cell cultures and of L-132 cells by protein kinase inhibitors (1993) (5)
- Inherited neuromuscular diseases. Translation from pathomechanisms to therapies. (2009) (4)
- Protein kinase C inhibitors, H7 and calphostin C, inhibit induction of DNA synthesis by cytosolic extracts of exponentially growing neuroblastoma cells in isolated nuclei (1994) (4)
- Long‐term ingestion of ammonium inhibits lysosomal proteolysis in rat liver (1988) (4)
- Transport of the precursor for rat liver glutamate dehydrogenase into mitochondria "in vitro". (1983) (4)
- A Multiomic Study To Unravel The Effects Of Developmental Exposure To Endosulfan In Rats: Molecular Explanation For Sex-Dependent Effects. (2019) (4)
- Current state of knowledge of hepatic encephalopathy (part II): changes in brain white matter tracts integrity are associated with cognitive deficits in minimal hepatic encephalopathy (2016) (4)
- H7, an inhibitor of protein kinase C, inhibits tumour cell division in mice bearing ascitic Ehrlich's carcinoma. (1994) (4)
- Apoptotic markers in the mitochondria, cytosol, and nuclei of brain cells during ammonia toxicity (2007) (4)
- Carnitine Inhibits Hydrolysis of Inositol Phospholipids Induced by Activation of Metabotropic Receptors (1998) (4)
- Trialkylglycines: a new family of compounds with in vivo neuroprotective activity. (2006) (4)
- Hyperammonemia induces brain tubulin. (1990) (4)
- Cirrhotic patients with minimal hepatic encephalopathy have increased capacity to eliminate superoxide and peroxynitrite in lymphocytes, associated with cognitive impairment (2018) (4)
- Effect of L-carnitine on postischemic inhibition of protein synthesis in the rat brain. (2009) (3)
- Extracellular cGMP Reverses Altered Membrane Expression of AMPA Receptors in Hippocampus of Hyperammonemic Rats: Underlying Mechanisms (2018) (3)
- Rifaximin Improves Spatial Learning and Memory Impairment in Rats with Liver Damage-Associated Neuroinflammation (2022) (3)
- Control of urea synthesis and ammonia detoxification. (1993) (3)
- The susceptibility of MAP-2 to proteolytic degradation increases when bound to tubulin (1992) (3)
- GAIT-GM: Galaxy tools for modeling metabolite changes as a function of gene expression (2020) (3)
- Translational research in hepatic encephalopathy: New diagnostic possibilities and new therapeutic approaches (2014) (3)
- 510 HYPERAMMONEMIA INCREASES GABAERGIC TONE IN CEREBELLUM BUT DECREASES IT IN CORTEX OF RATS. ROLE IN COGNITIVE IMPAIRMENT (2010) (3)
- Patients with Minimal Hepatic Encephalopathy Show Altered Thermal Sensitivity and Autonomic Function (2021) (3)
- Carbachol-Induced Hydrolysis of Phospholipids in Hippocampal Slices May Be Mediated in Part By Subsequent Activation of Metabotropic Glutamate Receptors (1998) (3)
- Determination of selected neurotoxic insecticides in small amounts of animal tissue utilizing a newly constructed mini-extractor (2017) (2)
- cGMP modulates stem cells differentiation to neurons in brain in vivo pathological implications (2011) (2)
- Role of nitric oxide and prostaglandins on the effects of endotoxin on gastric emptying (2001) (2)
- Metabolic syndrome is associated with poor response to rifaximin in minimal hepatic encephalopathy (2022) (2)
- 589 PATIENTS WITH MINIMAL HEPATIC ENCEPHALOPATHY SHOW IMPAIRED MISMATCH NEGATIVITY CORRELATING WITH REDUCED PERFORMANCE IN ATTENTION TESTS (2013) (2)
- A protein-free diet changes synaptosomal membrane fluidity and tyrosine and glutamate transport (1989) (2)
- Selective regional alterations in the content or distribution of neuronal and glial cytoskeletal proteins in brain of rats chronically exposed to 2,5-hexanedione (2002) (2)
- A Nextflow pipeline for T-cell receptor repertoire reconstruction and analysis from RNA sequencing data (2022) (2)
- Hyperammonemia Alters the Function of AMPA and NMDA Receptors in Hippocampus: Extracellular cGMP Reverses Some of These Alterations (2022) (2)
- 39th Annual European Brain and Behaviour Society Abstracts (2007) (2)
- Magnetic Resonance analysis of the effects of acute ammonia intoxication on a rat brain (2009) (2)
- The influence of HE history, HE status and neuropsychological test type on learning ability in patients with cirrhosis (2019) (2)
- A multi-omic study for uncovering molecular mechanisms associated with hyperammonemia-induced cerebellar function impairment in rats (2021) (2)
- Synthesis and transport of the precursor for the beta-subunit of rat liver F1-ATPase. (1984) (2)
- 230 Usefulness of the measurement of critical flicker frequency in the diagnosis of minimal hepatic encephalopathy (MHE) (2006) (2)
- Hyperammonemia Enhances GABAergic Neurotransmission in Hippocampus: Underlying Mechanisms and Modulation by Extracellular cGMP (2022) (1)
- Restoring the function of the glutamate-nitric oxide –cGMP pathway by treatments acting on different brain targets restores cognitive function in rats with minimal hepatic encephalopathy (2015) (1)
- Hyperammonemia and liver failure alter signal transduction associated with glutamate receptors and modulation of guanylate cyclase by nitric oxide (2003) (1)
- Extracellular cGMP Reverses Altered Membrane Expression of AMPA Receptors in Hippocampus of Hyperammonemic Rats: Underlying Mechanisms (2018) (1)
- Golexanolone, a GABAA receptor modulating steroid antagonist, restores motor coordination and cognitive function in hyperammonemic rats by dual effects on peripheral inflammation and neuroinflammation (2022) (1)
- Retention of actin synthesis in liver under conditions that inhibit synthesis of almost all other proteins (1987) (1)
- Hyperammonemia alters the mismatch negativity in the auditory evoked potential by altering functional connectivity and neurotransmission (2019) (1)
- Epigenetic modification of urea cycle enzymes in NAFLD animal models and patients: Implications for novel therapeutic approaches (2018) (1)
- Glutamatergic Neurotransmission, Aluminium and Alzheimer’s Disease (2001) (1)
- Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy (2016) (1)
- Enhanced BDNF and TrkB Activation Enhance GABA Neurotransmission in Cerebellum in Hyperammonemia (2022) (1)
- OC005: Ultrasound bioeffects: Quantification of cellular damage in animal fetal liver after use of Doppler pulse to measure ductus venosus (2008) (1)
- Sequential activation of soluble guanylate cyclase, cGMP-dependent protein kinase and cGMP-degrading phosphodiesterase is necessary for proper induction of long-term potentiation in the CA1 area of hippocampus (2003) (1)
- Developmental exposure to PCB153 and methylmercury on sex hormone levels at early and late postnatal periods in rats (2006) (1)
- Role of cGMP in learning: alterations in pathological situations and therapeutic implications (2005) (1)
- Sustained Hyperammonemia Activates NF-κB in Purkinje Neurons Through Activation of the TrkB-PI3K-AKT Pathway by Microglia-Derived BDNF in a Rat Model of Minimal Hepatic Encephalopathy (2023) (0)
- Restoration of learning in hepatic encephalopathy by pharmacological manipulation of cGMP levels in brain (2007) (0)
- Sildenafil Treatment Eliminates Pruritogenesis and Thermal Hyperalgesia in Rats with Portacaval Shunts (2016) (0)
- Minimal hepatic encephalopathy is associated with expansion and activation of CD4+CD28−, Th22 and Tfh and B lymphocytes (2017) (0)
- Research report Alteration of mitochondrial calcium homeostasis by ammonia-induced activation of NMDA receptors in rat brain in vivo (2000) (0)
- POLYMER CONJUGATES USE AS SINGLE AGENTS AND COMBINATION THERAPY: A VERSATILE 'TECHNOLOGY PLATFORM' FOR TISSUE REPAIR AND CANCER THERAPY. (2010) (0)
- Restoration of learning ability in rats with hyperammonemia and with liver failure by oral administration of sildenafil (2005) (0)
- The influence of hepatic encephalopathy (HE) history, HE status and neuropsychological test type on learning ability in patients with cirrhosis (2019) (0)
- Preface (2004) (0)
- Effect of a prolonged protein-free diet on cell size, protein synthesis and degradation of rat liver. (1989) (0)
- Comprar New Trends in Cancer for the 21st Century | Llombart-Bosch, Antonio | 9781402049668 | Springer (2007) (0)
- Presence of diadenosine polyphosphates in microdialysis samples from rat cerebellum in vivo: effect of mild hyperammonemia on their receptors (2013) (0)
- Metabolic syndrome is associated with poor response to rifaximin in minimal hepatic encephalopathy (2022) (0)
- Acute ammonia neurotoxicity in vivo involves the increase in cytoplasmic protein P53 without alterations in other markers of apoptosis (2006) (0)
- 526 HYPERAMMONEMIA AND INFLAMMATION IN THE INDUCTION OF MINIMAL HEPATIC ENCEPHALOPHATY (2010) (0)
- Trastornos metabólicos de la hapatopatía crónica. Metabolismo de los aminoácidos (1999) (0)
- Blocking NMDA Receptors Delays Death in Rats with Acute Liver Failure by Dual Protective Mechanisms in Kidney and Brain (2013) (0)
- SAT-085-Selective improvement by rifaximin of changes in the inmunophenotype in patients who improve minimal hepatic encephalopathy (2019) (0)
- Plasma Extracellular Vesicles Play a Role in Immune System Modulation in Minimal Hepatic Encephalopathy (2022) (0)
- P1296 : Blocking NMDA receptors prolongs survival in rats with acute liver failure by dual protective mechanisms in kidney and brain (2015) (0)
- Extracellular vesicles from hyperammonemic rats induce neuroinflammation in hippocampus and impair cognition in control rats (2023) (0)
- Extracellular vesicles from mesenchymal stem cells reduce neuroinflammation in hippocampus and restore cognitive function in hyperammonemic rats (2022) (0)
- Intracellular and extracelluar cyclic GMP in the brain and the hippocampus. (2022) (0)
- Altered cGMP content and activity of soluble guanylate cyclase in liver disease (2002) (0)
- Rats with Mild Bile Duct Ligation Show Hepatic Encephalopathy with Cognitive and Motor Impairment in the Absence of Cirrhosis: Effects of Alcohol Ingestion (2014) (0)
- Molecular Mechanisms of Neurological Alterations in Hepatic Encephalopathy (2010) (0)
- Hepatic encephalopathy. (2022) (0)
- Gene expression profiling in rat cerebellum and striatum following in utero and lactational exposure to non-dioxin-like polychlorinated biphenyls ☆ (2009) (0)
- Exploratory investigation on nitro- and phospho-proteome cerebellum changes in hyperammonemia and hepatic encephalopathy rat models (2011) (0)
- Methylmercury during development impairs the glutamate-NO-cGMP pathway and learning (2012) (0)
- Inhibition of γ-Secretase Leads to an Increase in Presenilin-1 (2017) (0)
- Mechanisms of developmental neurotoxicity: Molecular and behavioral correlates (2006) (0)
- Sustained hyperammonemia induces TNF-a IN Purkinje neurons by activating the TNFR1-NF-κB pathway (2020) (0)
- A rare and revealing glimpse of the cerebrospinal fluid of patients with hepatic encephalopathy. (2016) (0)
- Current state of knowledge of hepatic encephalopathy (part II): changes in brain white matter tracts integrity are associated with cognitive deficits in minimal hepatic encephalopathy (2016) (0)
- Developmental Exposure to Pesticides Alters Motor Activity and Coordination in Rats: Sex Differences and Underlying Mechanisms (2017) (0)
- Selective improvement by rifaximin of changes in the immunophenotype in patients who improve minimal hepatic encephalopathy (2019) (0)
- Minimal hepatic encephalopathy is associated with increased capacity to eliminate superoxide and peroxynitrite in lymphocytes (2017) (0)
- Treatment with anti-TNFa reduces neuroinflammation and restores neurotransmission, learning and motor coordination in rats with hepatic encephalopathy (2017) (0)
- Metabolism of cyclic GMP in non-alcoholic fatty liver disease in morbid obesity (2011) (0)
- A rat liver cell-free system for the synthesis of proteins and their transport into mitochondria. (1986) (0)
- Sildenafil Treatment Eliminates Pruritogenesis and Thermal Hyperalgesia in Rats with Portacaval Shunts (2017) (0)
- P0159 : Non invasive blood flow measurement by “arterial spin labeling” detects minimal hepatic encephalopathy (2015) (0)
- Extracellular Cyclic GMP Modulates Membrane Expression of The GluA1 and GluA2 Subunits of AMPA Receptor in Cerebellum: Molecular Mechanisms Involved (2017) (0)
- Characterization of alterations in mechanical, thermal and pain sensitivity in cirrhotic patients with minimal hepatic encephalopathy (2020) (0)
- Hyperammonemia alters membrane expression of GluA1 and GluA2 subunits of AMPA receptors in hippocampus by enhancing activation of the IL-1 receptor: underlying mechanisms (2018) (0)
- Content and modulation of soluble guanylate cyclase are altered in brain of cirrhotic patients: Differential alterations in cerebellum and cortex (2003) (0)
- Minimal hepatic encephalopathy is associated to alterations in eye movements (2022) (0)
- The effects of hyperammonemia in learning and brain metabolic activity (2014) (0)
- Chronic hyperammonemia, glutamatergic neurotransmission and neurological alterations (2012) (0)
- Chronic exposure to 2,5-hexanedione reversibly impairs learning of a conditional discrimination task in rats (2003) (0)
- Effects and Metabolism (2001) (0)
- 638 3-NITRO-TYROSINE AS A PERIPHERAL BIOMARKER OF MINIMAL HEPATIC ENCEPHALOPATHY IN PATIENTS WITH LIVER CIRRHOSIS (2012) (0)
- Inherited Neuromuscular Diseases (2009) (0)
- P: 56 Evaluation of Cognitive Dysfunction in Animal Models and Relatability to Human Disease (2019) (0)
- DETERMINANTS OF MATERNAL AND INFANTICIDAL BEHAVIOR IN FEMALE MOUSE F1 HYBRIDS (2007) (0)
- Rats with minimal hepatic encephalopathy due to portacaval shunt show differential increase of translocator protein (18 kDa) binding in different brain areas, which is not affected by chronic MAP-kinase p38 inhibition (2013) (0)
- Learning and Memory Impairments in Patients with Minimal Hepatic Encephalopathy are Associated with Structural and Functional Connectivity Alterations in Hippocampus (2018) (0)
- The expression levels of prolyl oligopeptidase responds not only to neuroinflammation but also to systemic inflammation upon liver failure in rat models and cirrhotic patients (2015) (0)
- P: 55 Decreased Cognitive Performance Is Associated With Reduced Resting State Connectivity and Gray Matter Atrophy in Patients With Minimal Hepatic Encephalopathy (2019) (0)
- Hyperammonemia induces glial activation, neuroinflammation and alters neurotransmitter receptors in hippocampus, impairing spatial learning: reversal by sulforaphane (2016) (0)
- Neuroinflammation increases GABAergic tone and impairs cognitive and motor function in hyperammonemia by increasing GAT-3 membrane expression. Reversal by sulforaphane by promoting M2 polarization of microglia (2016) (0)
- Blocking glycine receptors reduces neuroinflammation and restores neurotransmission in cerebellum through ADAM17-TNFR1-NF-κβ pathway (2020) (0)
- The Cerebellum of Patients with Steatohepatitis Shows Lymphocyte Infiltration, Microglial Activation and Loss of Purkinje and Granular Neurons (2018) (0)
- A multi-omic study for uncovering molecular mechanisms associated with hyperammonemia-induced cerebellar function impairment in rats (2021) (0)
- FRI-118-Decreased cognitive performance is associated with reduced resting state connectivity and gray matter atrophy in patients with minimal hepatic encephalopathy (2019) (0)
- Contribution of hyperammonemia and inflammatory factors to cognitive impairment in minimal hepatic encephalopathy (2011) (0)
- Chronic hyperammonemia alters the neurochemical and motor responses to activation of metabotropic glutamate receptors in the nucleus accumbens of rats in vivo (2005) (0)
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