Vicki Huff
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American geneticist and cancer researcher
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Vicki Huffbiology Degrees
Biology
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Genetics
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World Rank
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Biology
Vicki Huff's Degrees
- Bachelors Biology University of California, Berkeley
- PhD Genetics Stanford University
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Why Is Vicki Huff Influential?
(Suggest an Edit or Addition)According to Wikipedia, Vicki D. Huff is an American geneticist and cancer researcher. She is a professor in the department of genetics and the director of the Sequence and Microarray Facility at University of Texas MD Anderson Cancer Center. Huff is also a professor at UTHealth Graduate School of Biomedical Sciences. She completed a doctor of philosophy in human genetics at University of Michigan in 1987. From 1987 to 1990, Huff was a postdoctoral fellow in biochemistry and molecular biology at MD Anderson Cancer Center.
Vicki Huff's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Loss of heterozygosity for chromosomes 1p and 16q is an adverse prognostic factor in favorable-histology Wilms tumor: a report from the National Wilms Tumor Study Group. (2005) (359)
- Loss of heterozygosity for chromosomes 16q and 1p in Wilms' tumors predicts an adverse outcome. (1994) (254)
- Hereditary hyperparathyroidism-jaw tumor syndrome: the endocrine tumor gene HRPT2 maps to chromosome 1q21-q31. (1995) (248)
- Wilms' tumours: about tumour suppressor genes, an oncogene and a chameleon gene (2011) (246)
- The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis (2006) (225)
- Recurrent DGCR8, DROSHA, and SIX homeodomain mutations in favorable histology Wilms tumors. (2015) (210)
- Pleuropulmonary blastoma: a marker for familial disease. (1996) (203)
- Lack of linkage of familial Wilms' tumour to chromosomal band 11 p13 (1988) (203)
- A Children's Oncology Group and TARGET Initiative Exploring the Genetic Landscape of Wilms Tumor (2017) (201)
- Wilms tumor genetics: Mutations in WT1, WTX, and CTNNB1 account for only about one‐third of tumors (2008) (192)
- Frequent Association of β-Catenin and WT1 Mutations in Wilms Tumors (2000) (187)
- Sequential loss of heterozygosity at microsatellite motifs in preinvasive and invasive head and neck squamous carcinoma. (1995) (173)
- Evidence for WT1 as a Wilms tumor (WT) gene: intragenic germinal deletion in bilateral WT. (1991) (165)
- Wt1 negatively regulates β-catenin signaling during testis development (2008) (163)
- Wilms tumor genetics. (1998) (158)
- Treatment with nephrectomy only for small, stage I/favorable histology Wilms' tumor: a report from the National Wilms' Tumor Study Group. (2001) (142)
- Twenty‐four new cases of WT1 germline mutations and review of the literature: Genotype/phenotype correlations for Wilms tumor development (2004) (140)
- Treatment of Wilms tumor relapsing after initial treatment with vincristine, actinomycin D, and doxorubicin. A report from the National Wilms Tumor Study Group (2008) (134)
- Children's Oncology Group's 2013 blueprint for research: Renal tumors (2013) (133)
- Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models. (2010) (125)
- Denys-Drash syndrome: relating a clinical disorder to genetic alterations in the tumor suppressor gene WT1. (1993) (114)
- Frequent association of beta-catenin and WT1 mutations in Wilms tumors. (2000) (112)
- Linkage of familial Wilms' tumor predisposition to chromosome 19 and a two-locus model for the etiology of familial tumors. (1998) (110)
- Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylation. (2011) (109)
- The Wilms Tumor Gene, Wt1, Is Critical for Mouse Spermatogenesis via Regulation of Sertoli Cell Polarity and Is Associated with Non-Obstructive Azoospermia in Humans (2013) (99)
- Clinically relevant subsets identified by gene expression patterns support a revised ontogenic model of Wilms tumor: a Children's Oncology Group Study. (2012) (98)
- Treatment of Wilms tumor relapsing after initial treatment with vincristine and actinomycin D: A report from the National Wilms Tumor Study Group (2007) (93)
- β-catenin activation in a novel liver progenitor cell type is sufficient to cause hepatocellular carcinoma and hepatoblastoma. (2014) (86)
- Transcriptional regulation of the human Wilms' tumor gene (WT1). Cell type-specific enhancer and promiscuous promoter. (1994) (85)
- Genetic mosaicism in normal tissues of Wilms' tumour patients (1993) (79)
- Reprogramming of Sertoli cells to fetal-like Leydig cells by Wt1 ablation (2015) (76)
- Wt1 functions in ovarian follicle development by regulating granulosa cell differentiation. (2014) (73)
- Inheritance of Unequal Numbers of the Genes Encoding the Human Neutrophil Defensins HP-1 and HP-3 (*) (1995) (70)
- The Wt1+/R394W Mouse Displays Glomerulosclerosis and Early-Onset Renal Failure Characteristic of Human Denys-Drash Syndrome (2004) (70)
- Familial Wilms tumor (2004) (68)
- Long-term Outcomes for Infants With Very Low Risk Wilms Tumor Treated With Surgery Alone in National Wilms Tumor Study-5 (2010) (66)
- Significance of TP53 Mutation in Wilms Tumors with Diffuse Anaplasia: A Report from the Children's Oncology Group (2016) (65)
- Nonlinkage of 16q markers to familial predisposition to Wilms' tumor. (1992) (64)
- Microsatellite instability in preinvasive and invasive head and neck squamous carcinoma. (1996) (64)
- Structural analysis of the human nov proto-oncogene and expression in Wilms tumors (1994) (62)
- Clinical Outcome and Biological Predictors of Relapse After Nephrectomy Only for Very Low-risk Wilms Tumor: A Report From Children's Oncology Group AREN0532 (2017) (61)
- WT1 mutation and 11P15 loss of heterozygosity predict relapse in very low-risk wilms tumors treated with surgery alone: a children's oncology group study. (2011) (60)
- Rare variant detection using family-based sequencing analysis (2013) (57)
- Loss of Heterozygosity at 2q37 in Sporadic Wilms' Tumor: Putative Role for miR-562 (2009) (56)
- Wt1 directs the lineage specification of sertoli and granulosa cells by repressing Sf1 expression (2017) (56)
- MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours (2015) (53)
- Smallest region of overlap in Wilms tumor deletions uniquely implicates an 11p13 zinc finger gene as the disease locus. (1991) (53)
- Mutation in the PAX6 gene in twenty patients with aniridia (2000) (52)
- WT1 exon 1 deletion/insertion mutations in Wilms tumor patients, associated with di- and trinucleotide repeats and deletion hotspot consensus sequences. (1995) (50)
- Parental origin of de novo constitutional deletions of chromosomal band 11p13. (1990) (48)
- Upregulation of c-MYC in WT1-mutant tumors: assessment of WT1 putative transcriptional targets using cDNA microarray expression profiling of genetically defined Wilms' tumors (2003) (45)
- Frequent loss of imprinting at the IGF2 and H19 genes in head and neck squamous carcinoma (1999) (44)
- RNA expression of the WT1 gene in Wilms' tumors in relation to histology. (1992) (43)
- Wilms tumor genes. (1993) (42)
- Wilms’ Tumor Blastemal Stem Cells Dedifferentiate to Propagate the Tumor Bulk (2014) (42)
- Genotype/phenotype correlations in Wilms' tumor. (1996) (41)
- Wilms Tumor Predisposition (2016) (37)
- Characterization of the Inflammatory Microenvironment and Identification of Potential Therapeutic Targets in Wilms Tumors12 (2014) (36)
- Genome‐wide loss of heterozygosity analysis of WT1–wild‐type and WT1‐mutant Wilms tumors (2005) (30)
- Wilms Tumor Overview (2013) (30)
- Structural analysis of the human nov proto-oncogene and expression in Wilms tumor. (1994) (29)
- Evidence for genetic heterogeneity in familial Wilms' tumor. (1997) (28)
- Mediators of receptor tyrosine kinase activation in infantile fibrosarcoma: a Children's Oncology Group study (2012) (28)
- Allelic loss and replication errors at microsatellite loci on chromosome 11p in head and neck squamous carcinoma: association with aggressive biological features. (1996) (28)
- Pulmonary dysplasia, Denys-Drash syndrome and Wilms tumor 1 gene mutation in twins (2001) (27)
- Characterization of a Wilms tumor in a 9‐year‐old girl with trisomy 18 (2003) (27)
- A unique subset of low-risk Wilms tumors is characterized by loss of function of TRIM28 (KAP1), a gene critical in early renal development: A Children’s Oncology Group study (2018) (26)
- Nephron Progenitor But Not Stromal Progenitor Cells Give Rise to Wilms Tumors in Mouse Models with β-Catenin Activation or Wt1 Ablation and Igf2 Upregulation1 (2016) (24)
- Identification of germline DICER1 mutations and loss of heterozygosity in familial Wilms tumour (2015) (22)
- Race disparities in peptide profiles of North American and Kenyan Wilms tumor specimens. (2014) (22)
- Wt 1 ablation and Igf 2 upregulation in mice result in Wilms tumors with elevated ERK 1 / 2 phosphorylation (2010) (19)
- Ubiquitin specific protease 18 (Usp18) is a WT1 transcriptional target. (2013) (19)
- Monitoring Therapy with MEK Inhibitor U0126 in a Novel Wilms Tumor Model in Wt1 Knockout Igf2 Transgenic Mice Using 18F-FDG PET with Dual-Contrast Enhanced CT and MRI: Early Metabolic Response Without Inhibition of Tumor Growth (2012) (18)
- Bilateral gonadoblastoma with dysgerminoma and pilocytic astrocytoma with WT1 GT‐IVS9 mutation: A 46 XY phenotypic female with Frasier syndrome (2009) (16)
- Left‐sided cryptorchidism in mice with Wilms' tumour 1 gene deletion in gubernaculum testis (2013) (16)
- Familial Wilms' Tumor with Neural Elements: Characterization by Histology, Immunohistochemistry, and Genetic Analysis (2000) (15)
- Wt 1 directs the lineage specification of sertoli and granulosa cells by repressing Sf 1 expression (2016) (13)
- Analysis of possible abnormal WT1 RNA processing in primary Wilms tumors (1996) (11)
- Clinical outcome and biological predictors of relapse following nephrectomy only for very low risk Wilms tumor (VLR WT): A report from Children’s Oncology Group AREN0532. (2015) (11)
- Absence of PPP2R1A mutations in Wilms tumor (2001) (11)
- Wilms tumor genetics: a new, UnX-pected twist to the story. (2007) (9)
- Parental origin of WT1 mutations and mental retardation in WAGR syndrome (1994) (9)
- An EcoRI polymorphism associated with a human genomic clone from band 11p13. (1987) (8)
- Familial renal cell carcinoma: hereditary or coincidental? (1990) (6)
- Knock-in of the Wt1 R394W mutation causes MDS and cooperates with Flt3/ITD to drive aggressive myeloid neoplasms in mice (2018) (6)
- Erratum to Recurrent DGCR8, DROSHA, and SIX Homeodomain Mutations in Favorable Histology Wilms Tumors [Cancer Cell., 27, 286-297 (2015)] DOI: 10.1016/j.ccell.2015.02.008 (2015) (5)
- Genetic changes associated with relapse in favorable histology Wilms tumor: A Children’s Oncology Group AREN03B2 study (2022) (5)
- Analysis of possible WT1 RNA processing in primary Wilms tumors. (1996) (3)
- Universal Nephroblastomatosis with Bilateral Hyperplastic Nephromegaly in Siblings (2009) (3)
- Inheritance and functionality of Wilms' tumor genes (1994) (2)
- A Wilms Tumor 1 (WT1) Mutation Causes Myelodysplastic Syndrome in a Knock-in Mouse Model, and a Mixed Myelodysplastic/Myeloproliferative Neoplam in Double Knock-in Mice with WT1 and FLT3/ITD Mutations (2015) (1)
- A BglII RFLP detected by the probe JA8-1 at human chromosome band 11p13 (D11S417). (1990) (1)
- A panel of restriction fragment length polymorphisms for chromosomal band 11p13 (1990) (1)
- Molecular Genetics Of Wilms’ Tumor (1988) (0)
- Abstract LB-180: The genetic landscape of Wilms tumor (2016) (0)
- Abstract 5353: Comprehensive Ggnomic analysis of diffuse hyperplastic perilobar nephroblastomatosis (DHPLN) (2011) (0)
- Molecular genetics and cytogenetics of wilms' tumor (1989) (0)
- Abrogation of WT1 function in Wilms' tumors (1998) (0)
- Reply to B. Royer-Pokora et al (2011) (0)
- Abstract 5047: Impact of kidney progenitor cell differentiation status in Wilms tumorigenesis. (2013) (0)
- Role of Wilms' Tumor 1 in Sex Development (2022) (0)
- CHROMOSOME 11p13 ALTERATIONS IN WILMS TUMORS: 18 (1989) (0)
- Table 1. [Association of Nephrogenic Rests with Wilms Tumor Predisposition Syndromes and Congenital Anomalies]. (2013) (0)
- Abstract 1439: Loss of expression of SWI/SNF subunits in high risk Wilms tumor is accompanied by global gene expression changes (2012) (0)
- Wilms Tumor-Susceptibility Loci (1995) (0)
- The Genetic and Epigenetic Features of Bilateral Wilms Tumor Predisposition: A Report from the Children's Oncology Group AREN18B5-Q Study (2023) (0)
- Table 7. [NWTS-5 Guidelines for Surveillance of...]. (2013) (0)
- Table 3. [Molecular Genetics of Syndromic Wilms Tumor]. (2013) (0)
- An XmnI polymorphism detected by a human genomic clone from chromosomal band 11p13 [D11S416]. (1990) (0)
- Treatment W ith N ephrectomy O nly f or S mall, S tage I/Favorable H istology W ilms' T umor: A R eport F rom t he National W ilms' T umor S tudy G roup (2001) (0)
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