Victoria Cowling
#138,107
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English biologist
Victoria Cowling's AcademicInfluence.com Rankings
Victoria Cowlingbiology Degrees
Biology
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Molecular Biology
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Biology
Victoria Cowling's Degrees
- Bachelors Biology University of Oxford
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Why Is Victoria Cowling Influential?
(Suggest an Edit or Addition)According to Wikipedia, Victoria Haigh Cowling FRSE is an English biologist who received the Women in Cell Biology Early Career Medal from the British Society for Cell Biology in 2014. Cowling is Professor of Biology, Lister Institute Fellow, MRC Senior Fellow and Deputy Head of The Centre for Gene Regulation and Expression at the University of Dundee.
Victoria Cowling's Published Works
Published Works
- Caspase-6 is the direct activator of caspase-8 in the cytochrome c-induced apoptosis pathway: absolute requirement for removal of caspase-6 prodomain (2002) (260)
- Mechanism of transcriptional activation by the Myc oncoproteins. (2006) (185)
- Regulation of mRNA cap methylation (2009) (167)
- Cap-binding complex (CBC) (2013) (160)
- Transcription-independent functions of MYC: regulation of translation and DNA replication (2008) (149)
- The Myc Transactivation Domain Promotes Global Phosphorylation of the RNA Polymerase II Carboxy-Terminal Domain Independently of Direct DNA Binding (2007) (145)
- A Core MYC Gene Expression Signature Is Prominent in Basal-Like Breast Cancer but Only Partially Overlaps the Core Serum Response (2009) (137)
- Nestin is expressed in the basal/myoepithelial layer of the mammary gland and is a selective marker of basal epithelial breast tumors. (2007) (128)
- Binding Specificity and Regulation of the Serine Protease and PDZ Domains of HtrA2/Omi* (2003) (121)
- c-Myc Transforms Human Mammary Epithelial Cells through Repression of the Wnt Inhibitors DKK1 and SFRP1 (2007) (119)
- Single cell tuning of Myc expression by antigen receptor signal strength and interleukin-2 in T lymphocytes (2015) (117)
- A Conserved Myc Protein Domain, MBIV, Regulates DNA Binding, Apoptosis, Transformation, and G2 Arrest (2006) (107)
- Involvement of MINK, a Ste20 family kinase, in Ras oncogene-induced growth arrest in human ovarian surface epithelial cells. (2005) (98)
- mRNA cap regulation in mammalian cell function and fate☆ (2019) (98)
- SINE transcription by RNA polymerase III is suppressed by histone methylation but not by DNA methylation (2015) (72)
- Specific regulation of mRNA cap methylation by the c-Myc and E2F1 transcription factors (2009) (72)
- RAM/Fam103a1 Is Required for mRNA Cap Methylation (2011) (64)
- E-cadherin repression contributes to c-Myc-induced epithelial cell transformation (2007) (64)
- S-Adenosyl Homocysteine Hydrolase Is Required for Myc-Induced mRNA Cap Methylation, Protein Synthesis, and Cell Proliferation (2009) (61)
- Enhanced mRNA cap methylation increases Cyclin D1 expression and promotes cell transformation (2010) (48)
- Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM (2016) (46)
- Burkitt’s lymphoma-associated c-Myc mutations converge on a dramatically altered target gene response and implicate Nol5a/Nop56 in oncogenesis (2013) (40)
- Turning the Tables: Myc Activates Wnt in Breast Cancer (2007) (37)
- CDK1-Cyclin B1 Activates RNMT, Coordinating mRNA Cap Methylation with G1 Phase Transcription (2016) (37)
- Myc Regulation of mRNA Cap Methylation. (2010) (36)
- Human IFIT1 Inhibits mRNA Translation of Rubulaviruses but Not Other Members of the Paramyxoviridae Family (2016) (35)
- Human cap methyltransferase (RNMT) N-terminal non-catalytic domain mediates recruitment to transcription initiation sites (2013) (33)
- The Impact of KLF2 Modulation on the Transcriptional Program and Function of CD8 T Cells (2013) (32)
- Regulation and function of CMTR1‐dependent mRNA cap methylation (2017) (30)
- DHX15 regulates CMTR1-dependent gene expression and cell proliferation (2017) (27)
- mRNA Cap Methyltransferase, RNMT-RAM, Promotes RNA Pol II-Dependent Transcription (2018) (26)
- mRNA Cap Methylation in Pluripotency and Differentiation (2016) (25)
- Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase (2021) (23)
- CAP-MAP: cap analysis protocol with minimal analyte processing, a rapid and sensitive approach to analysing mRNA cap structures (2019) (22)
- Upregulation of RNA cap methyltransferase RNMT drives ribosome biogenesis during T cell activation (2021) (20)
- Myc and mRNA capping☆ (2015) (20)
- An N-Myc truncation analogous to c-Myc-S induces cell proliferation independently of transactivation but dependent on Myc homology box II (2007) (20)
- Positioning Europe for the EPITRANSCRIPTOMICS challenge (2018) (18)
- RAM function is dependent on Kapβ2-mediated nuclear entry (2013) (17)
- Regulation of mRNA capping in the cell cycle (2017) (17)
- E2F1-dependent methyl cap formation requires RNA pol II phosphorylation (2012) (16)
- Development of a High-Throughput Screening Assay to Identify Inhibitors of the SARS-CoV-2 Guanine-N7-Methyltransferase Using RapidFire Mass Spectrometry (2021) (14)
- The eukaryotic translation initiation factor eIF4E elevates steady-state m7G capping of coding and noncoding transcripts (2020) (14)
- CAPAM: The mRNA Cap Adenosine N6-Methyltransferase (2019) (13)
- Oncogenic PIK3CA mutations increase dependency on the mRNA cap methyltransferase, RNMT, in breast cancer cells (2019) (13)
- HATs Off to Capping: A New Mechanism for Myc (2007) (12)
- Mechanism of allosteric activation of human mRNA cap methyltransferase (RNMT) by RAM: insights from accelerated molecular dynamics simulations (2019) (12)
- c-Myc deregulation induces mRNA capping enzyme dependency (2016) (12)
- University of Dundee CDK 1-Cyclin B 1 Activates RNMT , Coordinating mRNA Cap Methylation with G 1 Phase Transcription (11)
- Myc up-regulates formation of the mRNA methyl cap. (2010) (10)
- To cap it all off, again: dynamic capping and recapping of coding and non-coding RNAs to control transcript fate and biological activity (2021) (7)
- Identification of SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of the nsp14 RNA Cap Methyltransferase (2021) (6)
- c-Myc co-ordinates mRNA cap methylation and ribosomal RNA production (2016) (6)
- Direct High‐Throughput Screening Assay for mRNA Cap Guanine‐N7 Methyltransferase Activity (2020) (3)
- The mRNA cap methyltransferase gene TbCMT1 is not essential in vitro but is a virulence factor in vivo for bloodstream form Trypanosoma brucei (2018) (3)
- CMTR1 is recruited to transcription start sites and promotes ribosomal protein and histone gene expression in embryonic stem cells (2022) (3)
- A novel RNA pol II CTD interaction site on the mRNA capping enzyme is essential for its allosteric activation (2021) (2)
- RAM / Fam 103 a 1 IsRequired formRNACapMethylation (2011) (1)
- Molecular details of RNA methyltransferase activity and allosteric regulation: A simulation study (2017) (0)
- Crystal structure of mRNA cap guanine-N7 methyltransferase in complex with RAM (2016) (0)
- DHX 15 regulates CMTR 1-dependent gene expression and cell proliferation (2018) (0)
- The RNA cap methyltransferases RNMT and CMTR1 co-ordinate gene expression during neural differentiation. (2023) (0)
- Crystal structure of mRNA cap guanine-N7 methyltransferase obtained by limited proteolysis (2016) (0)
- The ENHANCER LANDSCAPE INVOLVES a CORE NON-CODING RNA –PROTEIN INTERACTION NETWORK FOR C-Myc EXPRESSION (2015) (0)
- A Conserved Myc Protein Domain, MBIV, Regulates DNA Binding, Apoptosis, Transformation, and G2 Arrest (2006) (0)
- Cap methylation in pluripotency and differentiation (2016) (0)
- CMTR 1-dependent gene expression and cell proliferation (2018) (0)
- Faculty Opinions recommendation of Dynamics in protein translation sustaining T cell preparedness. (2020) (0)
- mRNA Cap Methyltransfer ase , RNMT-RAM , Promotes RNA Pol II-Dependent Transcription Graphical (2018) (0)
- Identification of novel RNA Polymerase II CTD interaction sites on the mRNA Capping Enzyme (2020) (0)
- Crystal structure of the mRNA cap guanine-N7 methyltransferase - modular lobe (416-456) deletion (2016) (0)
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