Vincent Dole
American physician
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Philosophy
Vincent Dole's Degrees
- Doctorate Medicine Columbia University
Why Is Vincent Dole Influential?
(Suggest an Edit or Addition)According to Wikipedia, Vincent Dole was an American doctor, who, along with his wife, Marie Nyswander , developed the use of methadone to treat heroin addiction. Dole and Nyswander, in establishing methadone maintenance treatment , improved treatment options in addiction medicine which for a century had been based on the conventional view that narcotic addiction was the result of an intractable moral defect. His work resulted in the partial re-legalization of opioid maintenance in the United States. For this contribution he was a recipient of the 1970 Canada Gairdner International Award, and the 1988 Albert Lasker Award for Clinical Medical Research.
Vincent Dole's Published Works
Published Works
- A relation between non-esterified fatty acids in plasma and the metabolism of glucose. (1956) (3204)
- Microdetermination of long-chain fatty acids in plasma and tissues. (1960) (2071)
- A MEDICAL TREATMENT FOR DIACETYLMORPHINE (HEROIN) ADDICTION. A CLINICAL TRIAL WITH METHADONE HYDROCHLORIDE. (1965) (1047)
- A Medical Treatment for Diacetylmorphine (Heroin) Addiction (1966) (521)
- Heroin addiction--a metabolic disease. (1967) (320)
- An Abnormality of Nonesterified Fatty Acid Metabolism in Diabetes Mellitus (1957) (318)
- Implications of methadone maintenance for theories of narcotic addiction. (1988) (256)
- Successful treatment of 750 criminal addicts. (1968) (247)
- Methadone treatment of randomly selected criminal addicts. (1969) (236)
- Narcotic blockade. (1966) (231)
- The fatty acid patterns of plasma lipids during alimentary lipemia. (1959) (217)
- Particulate fat in lymph and blood. (1962) (209)
- MEASUREMENT OF SPECIFIC GRAVITIES OF WHOLE BLOOD AND PLASMA BY STANDARD COPPER SULFATE SOLUTIONS (1950) (195)
- Action of insulin on release of fatty acids from tissue stores. (1957) (171)
- Methadone maintenance treatment. A ten-year perspective. (1976) (156)
- Effects of acute hemorrhagic and traumatic shock on renal function of dogs. (1946) (153)
- The use of orally-fed liquid formulas in metabolic studies. (1954) (143)
- Detection of narcotic drugs, tranquilizers, amphetamines, and barbiturates in urine. (1966) (129)
- HEROIN ADDICTION AND RELATED CLINICAL PROBLEMS (2002) (125)
- Rehabilitation of heroin addicts after blockade with methadone. (1966) (116)
- THE ELECTROPHORETIC PATTERNS OF NORMAL PLASMA. (1944) (113)
- Dietary treatment of hypertension; clinical and metabolic studies of patients on the rice-fruit diet. (1950) (113)
- Methadone plasma level: sustained by a reservoir of drug in tissue. (1973) (108)
- A Theory of Moving Boundary Systems Formed by Strong Electrolytes1 (1945) (107)
- Toward an analogue of alcoholism in mice: scale factors in the model. (1984) (106)
- On federal regulation of methadone treatment. (1995) (105)
- Dietary treatment of hypertension. II. Sodium depletion as related to the therapeutic effect. (1951) (94)
- THE PROPERTIES OF T ANTIGENS EXTRACTED FROM GROUP A HEMOLYTIC STREPTOCOCCI (1946) (92)
- Detoxification of rehabilitated methadone-maintained patients. (1973) (87)
- The significance of nonesterified fatty acids in plasma. (1958) (83)
- The caloric value of labile body tissue in obese subjects. (1955) (82)
- Effect of nucleic acid metabolites on lipolysis in adipose tissue. (1961) (80)
- CALCULATION OF HEMOGLOBIN FROM BLOOD SPECIFIC GRAVITIES (1950) (80)
- UREA EXCRETION IN HUMAN SWEAT AS A TRACER FOR MOVEMENT OF WATER WITHIN THE SECRETING GLAND (1953) (79)
- Methadone maintenance patients in general medical practice. A preliminary report. (1988) (76)
- AN INACTIVE PRECURSOR OF STREPTOCOCCAL PROTEINASE (1947) (76)
- Methadone treatment and the acquired immunodeficiency syndrome epidemic. (1989) (72)
- Pain management and chemical dependency. Evolving perspectives. (1997) (69)
- THE ESTIMATION OF PLASMA PROTEIN CONCENTRATION FROM PLASMA SPECIFIC GRAVITY (1950) (69)
- Narcotic addiction, physical dependence and relapse. (1972) (64)
- Biochemistry of addiction. (1970) (63)
- Metabolism of Amines. II: Mitochondrial Localization of Monoamine Oxidase (1951) (63)
- Toward an analogue of alcoholism in mice: criteria for recognition of pharmacologically motivated drinking. (1985) (58)
- The fatty acid pool in adipose tissue. (1961) (56)
- On the relevance of animal models to alcoholism in humans. (1986) (54)
- Methadone maintenance treatment for 25,000 heroin addicts. (1971) (52)
- Insulin-like actions of ribonucleic acid, adenylic acid, and adenosine. (1962) (51)
- Rehabilitation of the street addict. (1967) (50)
- Early experience and the consumption of alcohol by adult C57BL/6J mice. (1989) (49)
- Localization of d- and l-methadone after intraventricular injection into rat brains. (1970) (49)
- ELECTROPHORETIC CHANGES IN THE SERUM PROTEIN PATTERNS OF PATIENTS WITH SCARLET FEVER AND RHEUMATIC FEVER. (1945) (48)
- The renal extraction of oxygen in experimental shock. (1946) (44)
- BACK-DIFFUSION OF UREA IN THE MAMMALIAN KIDNEY (1943) (43)
- Copper Sulfate Method for measuring Specific Gravities of Whole Blood and Plasma, with Line Charts for calculating Plasma Proteins, Haemoglobin, and Hematoerit from Plasma and Whole Blood Gravities. (1938) (43)
- Body fat. (1959) (43)
- The use of methadone for narcotic blockade. (1968) (42)
- LONG‐TERM OUTCOMES AFTER TERMINATION FROM METHADONE MAINTENANCE TREATMENT * (1981) (40)
- The treatment of chronic pain. (1984) (39)
- Ethanol effects on harmaline-induced tremor and increase of cerebellar cyclic GMP. (1984) (39)
- Intake of water and ethanol by C57BL mice: Effect of an altered light-dark schedule (1983) (37)
- Performance-Based Rating of Methadone Maintenance Programs (1982) (36)
- An improved technique for monitoring the drinking behavior of mice (1983) (35)
- The activity of histaminase in tissues. (1952) (33)
- ELECTROPHORETIC CHANGES IN THE PLASMA PROTEIN PATTERNS OF PATIENTS WITH RELAPSING MALARIA. (1945) (33)
- Serial determination of plasma ethanol concentrations in mice (1983) (33)
- VARIATION IN THE FUNCTIONAL POWER OF HUMAN SWEAT GLANDS (1953) (32)
- Fractionation of Plasma Non-Esterified Fatty Acids (1956) (30)
- Narcotic blockade--a medical technique for stopping heroin use by addicts. (1966) (28)
- [Dietary treatment of hypertension. III. The effect of protein on appetite and weight]. (1953) (28)
- Metabolism of amines. I. Microdetermination of monoamine oxidase in tissues. (1951) (28)
- Electrophoretic changes in the serum of a patient with rheumatoid arthritis. (1947) (28)
- Arousal of ethanol-intoxicated comatose patients with naloxone. (1982) (28)
- What have we learned from three decades of methadone maintenance treatment? (1994) (27)
- Treatment of obesity with a low protein calorically unrestricted diet. (1954) (25)
- On the turnover of long-chain fatty acids in plasma. (1961) (24)
- Research on methadone maintenance treatment. (1970) (23)
- Toward an analogue of alcoholism in mice: analysis of nongenetic variance in consumption of alcohol. (1988) (23)
- The use of a formula diet for weight reduction of obese out-patients. (1958) (23)
- Study of methadone as an adjunct in rehabilitation of heroin addicts. (1966) (22)
- Radioassay of low activity fractions encountered in gas-liquid chromatography of long-chain fatty acids (1962) (21)
- A Dialyzable Medium for Cultivation of Group A Hemolytic Streptococci.∗ (1946) (21)
- DIODRAST AND INULIN CLEARANCES IN NEPHROTIC CHILDREN WITH SUPERNORMAL UREA CLEARANCES. (1943) (20)
- Addictive behavior. (1980) (19)
- Detoxification of sick addicts in prison. (1972) (19)
- Methadone maintenance. Outcome after termination. (1977) (19)
- Addiction as a public health problem. (1991) (18)
- Methadone maintenance: a theoretical perspective. (1980) (18)
- Hazards of process regulations. The example of methadone maintenance. (1992) (17)
- The present status of methadone blockade treatment. (1967) (16)
- Why does a sucrose choice reduce the consumption of alcohol in C57BL/6J mice? (1987) (16)
- Methadone poisoning. Diagnosis and treatment. (1971) (15)
- Rehabilitation of patients on methadone programs. (1973) (15)
- A relation between dietary protein and total calorie intake of large population groups. (1957) (15)
- Fat metabolism in diabetes. (1958) (15)
- Interim methadone clinics: an undervalued approach. (1991) (15)
- Elevated concentrations of ethanol in plasma do not suppress voluntary ethanol consumption in C57BL mice. (1983) (14)
- A nomogram for the calculation of relative centrifugal force. (1951) (13)
- Medical maintenance feasibility study. (1985) (13)
- Detection of narcotic, sedative, and amphetamine drugs in urine. Use of ion-exchange paper extraction. (1972) (13)
- Evaluation of narcotics treatment programs. (1967) (13)
- Detoxification of Methadone Patients, and Public Policy (1973) (12)
- ELECTROPHORETIC CHANGES IN THE SERUM PROTEIN PATTERN OF A PATIENT WITH TYPHUS FEVER. (1947) (12)
- THE BIPHASIC NATURE OF RENAL CALCIFICATION (1952) (12)
- Extraction of narcotic drugs, tranquilizers, and barbiturates by cation-exchange paper, and detection on a thin-layer chromatogram by a series of reagents. (1966) (11)
- Comments on "heroin maintenance". (1972) (11)
- The Significance of the Urea Clearance (1949) (10)
- On the Evaluation of Treatments for Narcotics Addiction (1979) (10)
- Fractionation of plasma nonesterified fatty acids. (1956) (9)
- PREDICTING POST-TREATMENT NARCOTIC USE AMONG PATIENTS TERMINATING FROM METHADONE MAINTENANCE (1982) (9)
- Detoxification of well rehabilitated methadone maintained patients. (1973) (9)
- A NOTE ON THE QUESTION OF REFLEX ACTIVATION OF DORSAL ROOT DILATORS (1940) (9)
- THOUGHTS ON NARCOTICS ADDICTION. (1965) (7)
- Methadone maintenance: optimizing dosage by estimating plasma level. (1994) (7)
- HYPERLIPEMIA AND ARTERIOSCLEROSIS. (1963) (7)
- 28. Methadone maintenance and its implication for theories of narcotic addiction. (1968) (6)
- Methadone Maintenance Comes of Age (1995) (6)
- Regulation of alcohol consumption. Individual appetite and social policy. (1983) (6)
- The operation of the data system in the methadone maintenance treatment program for heroin addiction. (1971) (6)
- The Treatment of Heroin Addiction (1966) (6)
- The role of protein in diets for weight reduction. (1957) (5)
- Addictive behaviour and the art of medicine. (1983) (4)
- Blockade with Methadone (1971) (4)
- Methadone treatment of narcotic addiction. (1971) (4)
- Selected bibliography on narcotic addiction treatment, 1960-1966. Reports of treatment programs. (1967) (4)
- Manipulation of alcohol preference in C57BL/6J mice by episodes of food poisoning. (1988) (3)
- IN THE COURSE OF PROFESSIONAL PRACTICE. (1965) (3)
- Rehabilitation of methadone patients. (1974) (3)
- CASE RECORDS OF THE MASSACHUSETTS GENERAL HOSPITAL. CASE 61-1963. (1963) (3)
- INCORPORATION OF FORMATE INTO LIPIDS OF ADIPOSE TISSUE. (1964) (3)
- Sounding Board. Performance-based rating of methadone maintenance programs. (1982) (2)
- The effect of chronic poisoning with carbon tetrachloride on voluntary consumption of ethanol by mice. (1981) (2)
- What is “Methadone Maintenance Treatment”? (1997) (2)
- Buprenorphine as a psychoactive drug (2006) (1)
- 8 – MANAGEMENT OF THE OPIATE ABSTINENCE SYNDROME (1976) (1)
- Heroin addiction--an epidemic disease. (1973) (1)
- Methadone Maintenance-Reply (1988) (1)
- PUBLICITY ABOUT A REDUCING DIET (1956) (1)
- Methadone and Theories of Addiction-Reply (1989) (1)
- Editorial: On Crash Programs (1959) (1)
- Precise determination of chloride in plasma by differential potentiometric titration. (1955) (1)
- ESTIMATION OF BLOOD VOLUME FROM CHANGE IN BLOOD SPECIFIC GRAVITY FOLLOWING A PLASMA INFUSION. (1946) (1)
- ETHANOL PRECIPITATION ANALYSIS OF THYMUS HISTONE (1957) (1)
- Narcotic blockade. 1966. (1991) (1)
- DETOXIFICATION CONSIDERATIONS IN THE MEDICAL MANAGEMENT OF SUBSTANCE ABUSE IN PREGNANCY* (2007) (0)
- Methadone treatment in British Columbia: bad medicine? (1987) (0)
- Research and development. (1979) (0)
- The Role of the Laboratory in the Treatment of Narcotic Poisoning (2008) (0)
- Research on addictive behavior. (1986) (0)
- Long-Acting Opioid-Agonists in the Treatment of Heroin Addiction: Why Should We Call Them "Substitution"? (2009) (0)
- [Cirrhosis of liver, alcoholic type]. (1947) (0)
- THE NEW CURRICULUM IN MATHEMATICS FOR BIOLOGISTS. INTERSECTION OF MATHEMATICS AND BIOLOGY. (1965) (0)
- An Abnormality of Nonesterified Fatty Acid Metabolism in Diabetes Mellitus (1958) (0)
- THE ELECTROPHORETIC PATTERNSOF NORMALPLASMA (2013) (0)
- Ventricular tachycardia after alcohol. (1980) (0)
- ELECTROPHORETIC CHANGES IN THE SERUM OF A PATIENT WITH RHEUMATOID ARTHRITIS. (1947) (0)
- The Investiture of Irving L. Schwartz as the first Dr. Harold and Golden Lamport Distinguished Service Professor, Physiology and Biophysics held on June 26, 1979 [sound recording] (1979) (0)
- GENERAL DISCUSSION (1981) (0)
- Release of T Precipitinogen into the Supernatant Fluid during Digestion of Streptococcal Cells (2003) (0)
- On crash programs. (1959) (0)
- Editorial: Detoxification of methadone patients, and public policy. (1973) (0)
- THE ROCKEFELLER diet. (1956) (0)
- Nine hundred calories. (1961) (0)
- Vocational rehabilitation of patients on the Beth Israel methadone maintenance program. (1974) (0)
- Donald Dexter Van Slyke 1883-1971. (1972) (0)
- Methadone doses: adequate and otherwise. Brief commentaries on Wolff and Hay's ‘Plasma methadone monitoring with methadone maintenance treatment’ (1994) (0)
- Ethical aspects and sociological implications of organ transplantation as a therapeutic procedure. (1969) (0)
- Heroin Add 7(2).indb (2005) (0)
- Pharmacological treatment of narcotic addiction (the eighth Nathan B. Eddy memorial award lecture). (1983) (0)
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