Vincenzo Di Marzo
#72,235
Most Influential Person Now
Researcher and university professor
Vincenzo Di Marzo's AcademicInfluence.com Rankings
Vincenzo Di Marzochemistry Degrees
Chemistry
#898
World Rank
#1465
Historical Rank
Organic Chemistry
#85
World Rank
#118
Historical Rank

Download Badge
Chemistry
Vincenzo Di Marzo's Degrees
- PhD Chemistry University of Naples Federico II
- Masters Chemistry University of Naples Federico II
- Bachelors Chemistry University of Naples Federico II
Why Is Vincenzo Di Marzo Influential?
(Suggest an Edit or Addition)Vincenzo Di Marzo's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide (1999) (2126)
- The endogenous cannabinoid system controls extinction of aversive memories (2002) (1659)
- Leptin-regulated endocannabinoids are involved in maintaining food intake (2001) (1556)
- Formation and inactivation of endogenous cannabinoid anandamide in central neurons (1994) (1548)
- International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2 (2010) (1504)
- Identification and Functional Characterization of Brainstem Cannabinoid CB2 Receptors (2005) (1434)
- CB1 Cannabinoid Receptors and On-Demand Defense Against Excitotoxicity (2003) (1134)
- The endocannabinoid system and its therapeutic exploitation (2004) (989)
- An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors (2002) (981)
- Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain (2003) (975)
- Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide (2001) (964)
- Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders (2014) (763)
- Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2‐arachidonoyl glycerol (2002) (760)
- Endocannabinoid control of food intake and energy balance (2005) (708)
- Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb. (2009) (691)
- Effects of cannabinoids and cannabinoid‐enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes (2011) (690)
- Targeting the endocannabinoid system: to enhance or reduce? (2008) (686)
- Endocannabinoids: endogenous cannabinoid receptor ligands with neuromodulatory action (1998) (684)
- Regulation, function, and dysregulation of endocannabinoids in models of adipose and beta-pancreatic cells and in obesity and hyperglycemia. (2006) (652)
- Evidence for a new G protein-coupled cannabinoid receptor in mouse brain. (2001) (547)
- An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity. (1998) (513)
- Endocannabinoid signaling at the periphery: 50 years after THC. (2015) (498)
- The endocannabinoid system: a general view and latest additions (2004) (485)
- Antitumor Activity of Plant Cannabinoids with Emphasis on the Effect of Cannabidiol on Human Breast Carcinoma (2006) (462)
- Immunohistochemical localization of cannabinoid type 1 and vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brain (2006) (460)
- The endocannabinoid system in energy homeostasis and the etiopathology of metabolic disorders. (2013) (429)
- The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation. (1998) (416)
- Are cannabidiol and Δ9‐tetrahydrocannabivarin negative modulators of the endocannabinoid system? A systematic review (2015) (397)
- Cannabinoids and the expanded endocannabinoid system in neurological disorders (2019) (391)
- Endocannabinoids control spasticity in a multiple sclerosis model (2001) (377)
- Circulating endocannabinoid levels, abdominal adiposity and related cardiometabolic risk factors in obese men (2007) (374)
- Biochemistry and pharmacology of endovanilloids. (2007) (374)
- Levels, Metabolism, and Pharmacological Activity of Anandamide in CB1 Cannabinoid Receptor Knockout Mice (2000) (373)
- Biosynthesis, Uptake, and Degradation of Anandamide and Palmitoylethanolamide in Leukocytes* (1997) (369)
- N-acyl-dopamines: novel synthetic CB(1) cannabinoid-receptor ligands and inhibitors of anandamide inactivation with cannabimimetic activity in vitro and in vivo. (2000) (363)
- Endocannabinoids and the control of energy balance (2007) (360)
- The Activity of Anandamide at Vanilloid VR1 Receptors Requires Facilitated Transport across the Cell Membrane and Is Limited by Intracellular Metabolism* (2001) (359)
- Overlap between the ligand recognition properties of the anandamide transporter and the VR1 vanilloid receptor: inhibitors of anandamide uptake with negligible capsaicin‐like activity (2000) (349)
- Intense exercise increases circulating endocannabinoid and BDNF levels in humans—Possible implications for reward and depression (2012) (343)
- N-Oleoyldopamine, a Novel Endogenous Capsaicin-like Lipid That Produces Hyperalgesia* (2003) (331)
- Identification of a New Class of Molecules, the Arachidonyl Amino Acids, and Characterization of One Member That Inhibits Pain* (2001) (322)
- Enhanced levels of endogenous cannabinoids in the globus pallidus are associated with a reduction in movement in an animal model of Parkinson's disease (2000) (321)
- Endocannabinoids and the regulation of their levels in health and disease (2007) (316)
- Biosynthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in circulating and tumoral macrophages. (1999) (311)
- Brain regional distribution of endocannabinoids: implications for their biosynthesis and biological function. (1999) (310)
- Endovanilloids. Putative endogenous ligands of transient receptor potential vanilloid 1 channels. (2004) (302)
- Possible endocannabinoid control of colorectal cancer growth. (2003) (293)
- From Phytocannabinoids to Cannabinoid Receptors and Endocannabinoids: Pleiotropic Physiological and Pathological Roles Through Complex Pharmacology. (2016) (289)
- Endocannabinoid signalling and the deteriorating brain (2014) (286)
- Changes in endocannabinoid contents in the brain of rats chronically exposed to nicotine, ethanol or cocaine (2002) (282)
- Elevation of Endocannabinoid Levels in the Ventrolateral Periaqueductal Grey through Inhibition of Fatty Acid Amide Hydrolase Affects Descending Nociceptive Pathways via Both Cannabinoid Receptor Type 1 and Transient Receptor Potential Vanilloid Type-1 Receptors (2006) (281)
- Nonpsychotropic plant cannabinoids, cannabidivarin (CBDV) and cannabidiol (CBD), activate and desensitize transient receptor potential vanilloid 1 (TRPV1) channels in vitro: potential for the treatment of neuronal hyperexcitability. (2014) (281)
- Plant-Derived Cannabinoids Modulate the Activity of Transient Receptor Potential Channels of Ankyrin Type-1 and Melastatin Type-8 (2008) (278)
- Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning (2008) (269)
- Biosynthesis, release and degradation of the novel endogenous cannabimimetic metabolite 2-arachidonoylglycerol in mouse neuroblastoma cells. (1997) (269)
- Attenuation of Allergic Contact Dermatitis Through the Endocannabinoid System (2007) (264)
- Analysis of cannabinoid receptor binding and mRNA expression and endogenous cannabinoid contents in the developing rat brain during late gestation and early postnatal period (1999) (263)
- Role in anxiety behavior of the endocannabinoid system in the prefrontal cortex. (2008) (262)
- Endocannabinoids and endocannabinoid-related mediators: Targets, metabolism and role in neurological disorders. (2016) (261)
- Cannabinoid CB1‐receptor mediated regulation of gastrointestinal motility in mice in a model of intestinal inflammation (2001) (259)
- Endovanilloid signaling in pain (2002) (258)
- Presynaptic Facilitation of Glutamatergic Synapses to Dopaminergic Neurons of the Rat Substantia Nigra by Endogenous Stimulation of Vanilloid Receptors (2003) (254)
- Blood Levels of the Endocannabinoid Anandamide are Increased in Anorexia Nervosa and in Binge-Eating Disorder, but not in Bulimia Nervosa (2005) (253)
- Endocannabinoid signalling in the blood of patients with schizophrenia (2003) (250)
- Anandamide and diet: Inclusion of dietary arachidonate and docosahexaenoate leads to increased brain levels of the corresponding N-acylethanolamines in piglets (2001) (248)
- ‘Endocannabinoids’ and other fatty acid derivatives with cannabimimetic properties: biochemistry and possible physiopathological relevance (1998) (246)
- Prefrontal Cortex Stimulation Induces 2-Arachidonoyl-Glycerol-Mediated Suppression of Excitation in Dopamine Neurons (2004) (245)
- Levels, metabolism, and pharmacological activity of anandamide in CB(1) cannabinoid receptor knockout mice: evidence for non-CB(1), non-CB(2) receptor-mediated actions of anandamide in mouse brain. (2000) (244)
- Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation (2012) (240)
- The palmitoylethanolamide and oleamide enigmas : are these two fatty acid amides cannabimimetic? (1999) (239)
- Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474 (2017) (237)
- Anandamide: some like it hot. (2001) (235)
- Structure‐activity relationship for the endogenous cannabinoid, anandamide, and certain of its analogues at vanilloid receptors in transfected cells and vas deferens (2001) (233)
- Anandamide acts as an intracellular messenger amplifying Ca2+ influx via TRPV1 channels (2005) (230)
- The Endocannabinoid System and its Modulation by Phytocannabinoids (2015) (226)
- Endocannabinoids may mediate the ability of (n-3) fatty acids to reduce ectopic fat and inflammatory mediators in obese Zucker rats. (2009) (224)
- The endocannabinoid signalling system: Biochemical aspects (2005) (217)
- Mechanisms of the Anti-Obesity Effects of Oxytocin in Diet-Induced Obese Rats (2011) (216)
- Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity (2017) (216)
- Changes in spinal and supraspinal endocannabinoid levels in neuropathic rats (2007) (216)
- The pharmacology of palmitoylethanolamide and first data on the therapeutic efficacy of some of its new formulations (2017) (214)
- Endocannabinoids and β-amyloid-induced neurotoxicity in vivo: effect of pharmacological elevation of endocannabinoid levels (2006) (213)
- The endocannabinoid system: Its general strategy of action, tools for its pharmacological manipulation and potential therapeutic exploitation (2009) (212)
- The vanilloid receptor (VR1)‐mediated effects of anandamide are potently enhanced by the cAMP‐dependent protein kinase (2001) (212)
- Cannabinoid CB1 Receptor Mediates Fear Extinction via Habituation-Like Processes (2006) (210)
- New perspectives on enigmatic vanilloid receptors (2000) (210)
- Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease. (2013) (209)
- Palmitoylethanolamide enhances anandamide stimulation of human vanilloid VR1 receptors (2001) (203)
- Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells. (1996) (203)
- Exogenous Anandamide Protects Rat Brain against Acute Neuronal Injury In Vivo (2001) (202)
- The novel endogenous cannabinoid 2-arachidonoylglycerol is inactivated by neuronal- and basophil-like cells: connections with anandamide. (1998) (202)
- Endocannabinoid Dysregulation in the Pancreas and Adipose Tissue of Mice Fed With a High‐fat Diet (2008) (199)
- Antibiotic-induced microbiota perturbation causes gut endocannabinoidome changes, hippocampal neuroglial reorganization and depression in mice (2018) (197)
- Anandamide Uptake by Human Endothelial Cells and Its Regulation by Nitric Oxide* (2000) (194)
- Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells. (2001) (194)
- Anxiolytic Effects in Mice of a Dual Blocker of Fatty Acid Amide Hydrolase and Transient Receptor Potential Vanilloid Type-1 Channels (2009) (192)
- A role for endocannabinoids in the generation of parkinsonism and levodopa‐induced dyskinesia in MPTP‐lesioned non‐human primate models of Parkinson's disease (2005) (191)
- Endocannabinoids as physiological regulators of colonic propulsion in mice. (2002) (191)
- Inhibitory effects of cannabinoid CB1 receptor stimulation on tumor growth and metastatic spreading: actions on signals involved in angiogenesis and metastasis (2003) (191)
- The endocannabinoid system: its general strategy of action, tools for its pharmacological manipulation and potential therapeutic exploitation. (2009) (190)
- Palmitoylethanolamide, endocannabinoids and related cannabimimetic compounds in protection against tissue inflammation and pain: potential use in companion animals. (2007) (190)
- Analgesic actions of N‐arachidonoyl‐serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors (2007) (190)
- Anandamide receptors. (2002) (188)
- Endocannabinoid system and mood disorders: priming a target for new therapies. (2013) (187)
- Cannabinoid receptors and their role in neuroprotection (2007) (186)
- Two novel classes of neuroactive fatty acid amides are substrates for mouse neuroblastoma ‘anandamide amidohydrolase’ (1995) (184)
- Suppression of nerve growth factor Trk receptors and prolactin receptors by endocannabinoids leads to inhibition of human breast and prostate cancer cell proliferation. (2000) (183)
- New approaches and challenges to targeting the endocannabinoid system (2018) (181)
- Unsaturated long-chain N-acyl-vanillyl-amides (N-AVAMs): vanilloid receptor ligands that inhibit anandamide-facilitated transport and bind to CB1 cannabinoid receptors. (1999) (181)
- Presence and regulation of the endocannabinoid system in human dendritic cells. (2002) (180)
- The endocannabinoid system in obesity and type 2 diabetes (2008) (180)
- Why do cannabinoid receptors have more than one endogenous ligand (2012) (180)
- Low fatty acid amide hydrolase and high anandamide levels are associated with failure to achieve an ongoing pregnancy after IVF and embryo transfer. (2002) (178)
- FAAH and MAGL inhibitors: therapeutic opportunities from regulating endocannabinoid levels. (2010) (177)
- Neuroprotection by the Endogenous Cannabinoid Anandamide and Arvanil against In Vivo Excitotoxicity in the Rat: Role of Vanilloid Receptors and Lipoxygenases (2003) (176)
- The endocannabinoid system in the basal ganglia and in the mesolimbic reward system: implications for neurological and psychiatric disorders (2003) (176)
- Involvement of the cAMP/protein kinase A pathway and of mitogen‐activated protein kinase in the anti‐proliferative effects of anandamide in human breast cancer cells (1999) (174)
- Sex steroid influence on cannabinoid CB(1) receptor mRNA and endocannabinoid levels in the anterior pituitary gland. (2000) (174)
- Plant, synthetic, and endogenous cannabinoids in medicine. (2006) (174)
- Targeting the endocannabinoid system in cancer therapy: A call for further research (2002) (172)
- Arachidonoylserotonin and other novel inhibitors of fatty acid amide hydrolase. (1998) (172)
- Changes in plasma endocannabinoid levels in viscerally obese men following a 1 year lifestyle modification programme and waist circumference reduction: associations with changes in metabolic risk factors (2009) (172)
- The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling (2008) (172)
- Non-CB1, Non-CB2 Receptors for Endocannabinoids, Plant Cannabinoids, and Synthetic Cannabimimetics: Focus on G-protein-coupled Receptors and Transient Receptor Potential Channels (2010) (171)
- Anandamide may mediate sleep induction (1997) (170)
- Endovanilloids. Putative endogenous ligands of transient receptor potential vanilloid 1 channels. (2004) (170)
- The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system. (2012) (169)
- Endocannabinoids and fatty acid amides in cancer, inflammation and related disorders. (2000) (169)
- Endocannabinoids: synthesis and degradation. (2008) (169)
- Enhancement of Anandamide Formation in the Limbic Forebrain and Reduction of Endocannabinoid Contents in the Striatum of Δ9‐Tetrahydrocannabinol‐Tolerant Rats (2000) (166)
- Anandamide inhibits adhesion and migration of breast cancer cells. (2006) (165)
- Dysregulation of peripheral endocannabinoid levels in hyperglycemia and obesity: Effect of high fat diets (2008) (165)
- The uptake by cells of 2-arachidonoylglycerol, an endogenous agonist of cannabinoid receptors. (2001) (164)
- Non‐THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro‐apoptotic effects and underlying mechanisms (2013) (163)
- N-Arachidonoyl-Dopamine Tunes Synaptic Transmission onto Dopaminergic Neurons by Activating both Cannabinoid and Vanilloid Receptors (2007) (161)
- Tonic Endovanilloid Facilitation of Glutamate Release in Brainstem Descending Antinociceptive Pathways (2007) (160)
- Finding of the endocannabinoid signalling system in Hydra, a very primitive organism: possible role in the feeding response (1999) (160)
- Phosphatidic Acid as the Biosynthetic Precursor of the Endocannabinoid 2‐Arachidonoylglycerol in Intact Mouse Neuroblastoma Cells Stimulated with Ionomycin (1999) (159)
- The endocannabinoid system as a link between homoeostatic and hedonic pathways involved in energy balance regulation (2009) (158)
- Lipopolysaccharide downregulates fatty acid amide hydrolase expression and increases anandamide levels in human peripheral lymphocytes. (2001) (157)
- Control by the endogenous cannabinoid system of ras oncogene‐dependent tumor growth (2001) (156)
- Phytocannabinoids beyond the Cannabis plant – do they exist? (2010) (156)
- Interactions between synthetic vanilloids and the endogenous cannabinoid system (1998) (155)
- Evolutionary origins of the endocannabinoid system. (2006) (155)
- Pharmacological enhancement of the endocannabinoid system in the nucleus accumbens shell stimulates food intake and increases c‐Fos expression in the hypothalamus (2007) (153)
- Endogenous cannabinoids in the brain and peripheral tissues: regulation of their levels and control of food intake (2006) (153)
- Endocannabinoids: synthesis and degradation. (2006) (153)
- A new strategy to block tumor growth by inhibiting endocannabinoid inactivation (2004) (152)
- Novel selective and metabolically stable inhibitors of anandamide cellular uptake. (2003) (151)
- Peripheral endocannabinoid dysregulation in obesity: relation to intestinal motility and energy processing induced by food deprivation and re‐feeding (2009) (151)
- The endocannabinoid system in the basal ganglia and in the mesolimbic reward system: implications for neurological and psychiatric disorders. (2003) (148)
- An NMR spectroscopic method to identify and classify thiol-trapping agents: revival of Michael acceptors for drug discovery? (2011) (148)
- The biosynthesis, fate and pharmacological properties of endocannabinoids. (2005) (147)
- Anandamide, an endogenous cannabinomimetic eicosanoid: 'killing two birds with one stone'. (1995) (146)
- Prostaglandin Ethanolamides (Prostamides): In Vitro Pharmacology and Metabolism (2004) (146)
- Cannabidiol, a safe and non-psychotropic ingredient of the marijuana plant Cannabis sativa, is protective in a murine model of colitis (2009) (146)
- TRPV1 receptors in the central nervous system: potential for previously unforeseen therapeutic applications. (2008) (145)
- Adolescent exposure to THC in female rats disrupts developmental changes in the prefrontal cortex (2015) (145)
- Dual effect of cannabinoid CB1 receptor stimulation on a vanilloid VR1 receptor-mediated response (2003) (143)
- Further evidence for the existence of a specific process for the membrane transport of anandamide. (2004) (143)
- Endocannabinoids in Amygdala and Nucleus Accumbens Mediate Social Play Reward in Adolescent Rats (2012) (141)
- Non‐psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action (2011) (141)
- Cannabinoid receptors and endocannabinoids: role in neuroinflammatory and neurodegenerative disorders. (2010) (141)
- At the heart of the matter: the endocannabinoid system in cardiovascular function and dysfunction. (2012) (140)
- Cannabimimetic fatty acid derivatives: the anandamide family and other endocannabinoids. (1999) (140)
- An introduction to the endocannabinoid system: from the early to the latest concepts (2009) (140)
- Regulation of transient receptor potential channels of melastatin type 8 (TRPM8): effect of cAMP, cannabinoid CB(1) receptors and endovanilloids. (2007) (140)
- Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer (2012) (139)
- Endocannabinoids Activate Transient Receptor Potential Vanilloid 1 Receptors to Reduce Hyperdopaminergia-Related Hyperactivity: Therapeutic Implications (2006) (139)
- Palmitoylethanolamide, a naturally occurring lipid, is an orally effective intestinal anti‐inflammatory agent (2015) (139)
- Up-regulation of anandamide levels as an endogenous mechanism and a pharmacological strategy to limit colon inflammation. (2006) (138)
- Increasing cannabinoid levels by pharmacological and genetic manipulation delays disease progression in SOD1 mice (2006) (136)
- Normal human pituitary gland and pituitary adenomas express cannabinoid receptor type 1 and synthesize endogenous cannabinoids: first evidence for a direct role of cannabinoids on hormone modulation at the human pituitary level. (2001) (136)
- Pharmacological modulation of the endocannabinoid system in a viral model of multiple sclerosis (2005) (136)
- The endovanilloid/endocannabinoid system in human osteoclasts: possible involvement in bone formation and resorption. (2009) (136)
- Hypolocomotor effects in rats of capsaicin and two long chain capsaicin homologues. (2001) (135)
- Effect of dietary krill oil supplementation on the endocannabinoidome of metabolically relevant tissues from high-fat-fed mice (2011) (135)
- Depolarization‐induced retrograde synaptic inhibition in the mouse cerebellar cortex is mediated by 2‐arachidonoylglycerol (2006) (135)
- N-palmitoyl-ethanolamine: Biochemistry and new therapeutic opportunities. (2010) (135)
- An endogenous cannabinoid tone attenuates cholera toxin-induced fluid accumulation in mice. (2003) (134)
- Involvement of the cannabimimetic compound, N-palmitoyl-ethanolamine, in inflammatory and neuropathic conditions: Review of the available pre-clinical data, and first human studies (2005) (134)
- Compounds acting at the endocannabinoid and/or endovanilloid systems reduce hyperkinesia in a rat model of Huntington's disease (2003) (129)
- Cannabinoid Receptor 1 Blockade Ameliorates Albuminuria in Experimental Diabetic Nephropathy (2010) (129)
- Biochemistry of the Endogenous Ligands of Cannabinoid Receptors (1998) (128)
- Fatty acid amide hydrolase controls mouse intestinal motility in vivo. (2005) (128)
- Differential diurnal variations of anandamide and 2-arachidonoyl-glycerol levels in rat brain (2004) (128)
- Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis (2005) (128)
- Elevated endocannabinoid plasma levels are associated with coronary circulatory dysfunction in obesity. (2011) (127)
- Hedonic eating is associated with increased peripheral levels of ghrelin and the endocannabinoid 2-arachidonoyl-glycerol in healthy humans: a pilot study. (2012) (127)
- Care and Feeding of the Endocannabinoid System: A Systematic Review of Potential Clinical Interventions that Upregulate the Endocannabinoid System (2014) (127)
- Anandamide inhibits nuclear factor-kappaB activation through a cannabinoid receptor-independent pathway. (2003) (127)
- Suppression of Nerve Growth Factor Trk Receptors and Prolactin Receptors by Endocannabinoids Leads to Inhibition of Human Breast and Prostate Cancer Cell Proliferation1. (2000) (126)
- Protective Role of Cannabinoid Receptor Type 2 in a Mouse Model of Diabetic Nephropathy (2011) (126)
- CB1 antagonists for obesity—what lessons have we learned from rimonabant? (2009) (125)
- Noladin ether, a putative novel endocannabinoid: inactivation mechanisms and a sensitive method for its quantification in rat tissues (2002) (125)
- Acute neuronal injury, excitotoxicity, and the endocannabinoid system (2002) (125)
- Arvanil, anandamide and N‐arachidonoyl‐dopamine (NADA) inhibit emesis through cannabinoid CB1 and vanilloid TRPV1 receptors in the ferret (2007) (124)
- Up‐regulation of anandamide levels as an endogenous mechanism and a pharmacological strategy to limit colon inflammation (2006) (124)
- Biosynthesis and inactivation of N-arachidonoylethanolamine (anandamide) and N-docosahexaenoylethanolamine in bovine retina. (1999) (123)
- Combining Mass Spectrometric Metabolic Profiling with Genomic Analysis: A Powerful Approach for Discovering Natural Products from Cyanobacteria. (2015) (122)
- Activation of the endocannabinoid system as a therapeutic approach in a murine model of multiple sclerosis (2005) (122)
- New approaches and challenges to targeting the endocannabinoid system (2018) (122)
- Critical role of the endogenous cannabinoid system in mouse pup suckling and growth. (2001) (121)
- Obesity-driven synaptic remodeling affects endocannabinoid control of orexinergic neurons (2013) (121)
- Development of the first potent and specific inhibitors of endocannabinoid biosynthesis. (2006) (121)
- An introduction to the endocannabinoid system: from the early to the latest concepts. (2009) (120)
- The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis (2009) (120)
- The cannabinoid TRPA1 agonist cannabichromene inhibits nitric oxide production in macrophages and ameliorates murine colitis (2013) (118)
- Inhibitory effect of cannabichromene, a major non‐psychotropic cannabinoid extracted from Cannabis sativa, on inflammation‐induced hypermotility in mice (2012) (117)
- Endocannabinoid signaling in the brain: biosynthetic mechanisms in the limelight (2010) (117)
- Novel inhibitors of brain, neuronal, and basophilic anandamide amidohydrolase. (1997) (117)
- 'Endocannabinoids' and other fatty acid derivatives with cannabimimetic properties: biochemistry and possible physiopathological relevance. (1998) (117)
- Endocannabinoid overactivity and intestinal inflammation (2006) (115)
- Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon (2007) (115)
- Comparative biology of the endocannabinoid system (2000) (114)
- Role of insulin as a negative regulator of plasma endocannabinoid levels in obese and nonobese subjects. (2009) (114)
- Protective role of palmitoylethanolamide in contact allergic dermatitis (2009) (113)
- Endocannabinoids and related compounds: walking back and forth between plant natural products and animal physiology. (2007) (113)
- Trick or treat from food endocannabinoids? (1998) (113)
- Highly selective CB(1) cannabinoid receptor ligands and novel CB(1)/VR(1) vanilloid receptor "hybrid" ligands. (2001) (112)
- The endocannabinoid system is modulated in response to spinal cord injury in rats (2009) (110)
- Neural precursor cells induce cell death of high-grade astrocytomas via stimulation of TRPV1 (2012) (109)
- The plant cannabinoid Δ9‐tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice (2010) (109)
- Immunohistochemical localization of anabolic and catabolic enzymes for anandamide and other putative endovanilloids in the hippocampus and cerebellar cortex of the mouse brain (2008) (109)
- Role of the endogenous cannabinoid system in the formalin test of persistent pain in the rat. (2000) (108)
- Inhibitory effect of palmitoylethanolamide on gastrointestinal motility in mice (2001) (108)
- Fatty acid amide hydrolase, an enzyme with many bioactive substrates. Possible therapeutic implications. (2002) (108)
- Finding of endocannabinoids in human eye tissues: implications for glaucoma. (2005) (107)
- Actions of two naturally occurring saturated N‐acyldopamines on transient receptor potential vanilloid 1 (TRPV1) channels (2004) (107)
- The anti‐inflammatory mediator palmitoylethanolamide enhances the levels of 2‐arachidonoyl‐glycerol and potentiates its actions at TRPV1 cation channels (2016) (106)
- Novel bioactive metabolites of dipyrone (metamizol). (2012) (106)
- The role of endocannabinoids in the regulation of gastric emptying: alterations in mice fed a high‐fat diet (2008) (105)
- Study of the regulation of the endocannabinoid system in a virus model of multiple sclerosis reveals a therapeutic effect of palmitoylethanolamide (2008) (105)
- Discovery of Prostamide F2α and Its Role in Inflammatory Pain and Dorsal Horn Nociceptive Neuron Hyperexcitability (2012) (104)
- Endocannabinoids and energy homeostasis: An update (2014) (103)
- Effect of polyunsaturated fatty acids on endocannabinoid and N-acyl-ethanolamine levels in mouse adipocytes. (2008) (102)
- Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes. (2011) (101)
- Palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis in the medial prefrontal cortex of neuropathic mice (2015) (101)
- Role and regulation of acylethanolamides in energy balance: focus on adipocytes and β‐cells (2007) (100)
- Protective activation of the endocannabinoid system during ischemia in dopamine neurons (2006) (100)
- FAAH and anandamide: is 2-AG really the odd one out? (2008) (99)
- Potential biosynthetic connections between the two cannabimimetic eicosanoids, anandamide and 2-arachidonoyl-glycerol, in mouse neuroblastoma cells. (1996) (99)
- In vivo pharmacological actions of two novel inhibitors of anandamide cellular uptake. (2004) (98)
- The endocannabinoid system and the molecular basis of paralytic ileus in mice (2002) (97)
- Krill oil significantly decreases 2-arachidonoylglycerol plasma levels in obese subjects (2011) (95)
- Human lung‐resident macrophages express CB1 and CB2 receptors whose activation inhibits the release of angiogenic and lymphangiogenic factors (2016) (93)
- Anti-inflammatory Properties of Cannabidiol, a Nonpsychotropic Cannabinoid, in Experimental Allergic Contact Dermatitis (2018) (93)
- Identification of Endocannabinoids and Cannabinoid CB1 Receptor mRNA in the Pituitary Gland (1999) (93)
- Changes in endocannabinoid levels in a rat model of behavioural sensitization to morphine (2004) (92)
- Changes in endocannabinoid transmission in the basal ganglia in a rat model of Huntington's disease (2001) (92)
- Selective inhibition of anandamide cellular uptake versus enzymatic hydrolysis--a difficult issue to handle. (2004) (92)
- Identification of Endocannabinoids and Related Compounds in Human Fat Cells (2007) (91)
- Palmitoylethanolamide counteracts reactive astrogliosis induced by β-amyloid peptide (2011) (91)
- Cannabinoid receptors are absent in insects (2001) (91)
- Biosynthesis and degradation of bioactive fatty acid amides in human breast cancer and rat pheochromocytoma cells--implications for cell proliferation and differentiation. (1998) (90)
- TRPV1-dependent and -independent alterations in the limbic cortex of neuropathic mice: impact on glial caspases and pain perception. (2012) (90)
- TRPV1 channels control synaptic plasticity in the developing superior colliculus (2009) (89)
- Effect on cancer cell proliferation of palmitoylethanolamide, a fatty acid amide interacting with both the cannabinoid and vanilloid signalling systems (2002) (88)
- An Orally Active Cannabis Extract with High Content in Cannabidiol attenuates Chemically-induced Intestinal Inflammation and Hypermotility in the Mouse (2016) (88)
- Antiepileptic action of N-palmitoylethanolamine through CB1 and PPAR-α receptor activation in a genetic model of absence epilepsy (2013) (88)
- Intestinal epithelial N-acylphosphatidylethanolamine phospholipase D links dietary fat to metabolic adaptations in obesity and steatosis (2019) (88)
- Improvement in coronary circulatory function in morbidly obese individuals after gastric bypass-induced weight loss: relation to alterations in endocannabinoids and adipocytokines. (2013) (87)
- Endocannabinoids: A unique opportunity to develop multitarget analgesics (2013) (87)
- An endocannabinoid tone limits excitotoxicity in vitro and in a model of multiple sclerosis (2010) (87)
- Occurrence and metabolism of anandamide and related acyl-ethanolamides in ovaries of the sea urchin Paracentrotus lividus. (1997) (86)
- The cannabinoid Δ9-tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesity (2013) (86)
- Full Inhibition of Spinal FAAH Leads to TRPV1-Mediated Analgesic Effects in Neuropathic Rats and Possible Lipoxygenase-Mediated Remodeling of Anandamide Metabolism (2013) (86)
- The blockade of the transient receptor potential vanilloid type 1 and fatty acid amide hydrolase decreases symptoms and central sequelae in the medial prefrontal cortex of neuropathic rats (2011) (85)
- Why do cannabinoid receptors have more than one endogenous ligand? (2012) (85)
- A structure/activity relationship study on arvanil, an endocannabinoid and vanilloid hybrid. (2002) (85)
- Endocannabinoids in nervous system health and disease: the big picture in a nutshell (2012) (84)
- Chronic Morphine Modulates the Contents of the Endocannabinoid, 2-Arachidonoyl Glycerol, in Rat Brain (2003) (83)
- Palmitoylethanolamide induces microglia changes associated with increased migration and phagocytic activity: involvement of the CB2 receptor (2017) (83)
- Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients (2010) (83)
- Poly-ε-caprolactone microspheres as a drug delivery system for cannabinoid administration: development, characterization and in vitro evaluation of their antitumoral efficacy. (2012) (83)
- Inhibitory effect of salvinorin A, from Salvia divinorum, on ileitis‐induced hypermotility: cross‐talk between κ‐opioid and cannabinoid CB1 receptors (2008) (82)
- The A1 adenosine receptor as a new player in microglia physiology (2014) (82)
- Gender‐dependent cellular and biochemical effects of maternal deprivation on the hippocampus of neonatal rats: A possible role for the endocannabinoid system (2008) (82)
- The activation of the cannabinoid receptor type 2 reduces neutrophilic protease-mediated vulnerability in atherosclerotic plaques. (2012) (82)
- Neurobehavioral activity in mice of N-vanillyl-arachidonyl-amide. (2000) (82)
- Second generation CB1 receptor blockers and other inhibitors of peripheral endocannabinoid overactivity and the rationale of their use against metabolic disorders (2012) (82)
- Involvement of the endocannabinoid system in phencyclidine-induced cognitive deficits modelling schizophrenia. (2009) (81)
- Endocannabinoids as regulators of transient receptor potential (TRP) channels: A further opportunity to develop new endocannabinoid-based therapeutic drugs. (2010) (81)
- Effect of repeated systemic administration of selective inhibitors of endocannabinoid inactivation on rat brain endocannabinoid levels. (2005) (81)
- Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration. (2006) (81)
- Targeting the endocannabinoid system: to enhance or reduce? (2008) (80)
- Peripheral effects of the endocannabinoid system in energy homeostasis: Adipose tissue, liver and skeletal muscle (2011) (80)
- Symptom-related changes of endocannabinoid and palmitoylethanolamide levels in brain areas of R6/2 mice, a transgenic model of Huntington's disease (2008) (80)
- Arvanil-induced inhibition of spasticity and persistent pain: evidence for therapeutic sites of action different from the vanilloid VR1 receptor and cannabinoid CB(1)/CB(2) receptors. (2002) (80)
- Tetrahydrolipstatin analogues as modulators of endocannabinoid 2-arachidonoylglycerol metabolism. (2008) (79)
- The biosynthesis of N-arachidonoyl dopamine (NADA), a putative endocannabinoid and endovanilloid, via conjugation of arachidonic acid with dopamine. (2009) (79)
- Dietary krill oil increases docosahexaenoic acid and reduces 2-arachidonoylglycerol but not N-acylethanolamine levels in the brain of obese Zucker rats (2010) (79)
- From endocannabinoid profiling to 'endocannabinoid therapeutics'. (2009) (78)
- Endocannabinoid metabolic pathways and enzymes. (2005) (78)
- Analysis of anandamide, an endogenous cannabinoid substance, and of other natural N-acylethanolamines. (1995) (78)
- Randomised clinical trial: the analgesic properties of dietary supplementation with palmitoylethanolamide and polydatin in irritable bowel syndrome (2017) (78)
- Mechanisms for the coupling of cannabinoid receptors to intracellular calcium mobilization in rat insulinoma beta-cells. (2007) (77)
- Effect of dietary fat on endocannabinoids and related mediators: consequences on energy homeostasis, inflammation and mood. (2010) (77)
- Changes in endocannabinoid contents in reward‐related brain regions of alcohol‐exposed rats, and their possible relevance to alcohol relapse (2004) (77)
- Opposing Control of Cannabinoid Receptor Stimulation on Amyloid-β-Induced Reactive Gliosis: In Vitro and in Vivo Evidence (2007) (77)
- The endocannabinoid system in obesity and type 2 diabetes. (2008) (77)
- CB1 receptor antagonism: biological basis for metabolic effects (2008) (76)
- Neuropathic pain and the endocannabinoid system in the dorsal raphe: pharmacological treatment and interactions with the serotonergic system (2006) (76)
- The Endocannabinoid 2-Arachidonoylglycerol Is Responsible for the Slow Self-Inhibition in Neocortical Interneurons (2008) (76)
- 2-AG promotes the expression of conditioned fear via cannabinoid receptor type 1 on GABAergic neurons (2015) (76)
- Neural contractions in colonic strips from patients with diverticular disease: role of endocannabinoids and substance P (2006) (75)
- Lipids as regulators of the activity of transient receptor potential type V1 (TRPV1) channels. (2005) (75)
- Regulation and possible role of endocannabinoids and related mediators in hypercholesterolemic mice with atherosclerosis. (2009) (74)
- Palmitoylethanolamide normalizes intestinal motility in a model of post‐inflammatory accelerated transit: involvement of CB1 receptors and TRPV1 channels (2014) (74)
- Circulating and hepatic endocannabinoids and endocannabinoid‐related molecules in patients with cirrhosis (2009) (74)
- A role for vanilloid receptor 1 (TRPV1) and endocannabinnoid signalling in the regulation of spontaneous and L-DOPA induced locomotion in normal and reserpine-treated rats (2006) (74)
- "Redundancy" of endocannabinoid inactivation: new challenges and opportunities for pain control. (2012) (73)
- Lifestyle and Metabolic Syndrome: Contribution of the Endocannabinoidome (2019) (73)
- Development of a potent inhibitor of 2-arachidonoylglycerol hydrolysis with antinociceptive activity in vivo. (2009) (73)
- The inhibition of 2-arachidonoyl-glycerol (2-AG) biosynthesis, rather than enhancing striatal damage, protects striatal neurons from malonate-induced death: a potential role of cyclooxygenase-2-dependent metabolism of 2-AG (2013) (73)
- Non-CB1, Non-CB2 Receptors for Endocannabinoids, Plant Cannabinoids, and Synthetic Cannabimimetics: Focus on G-protein-coupled Receptors and Transient Receptor Potential Channels (2010) (73)
- Synthesis and biological evaluation of novel amides of polyunsaturated fatty acids with dopamine. (2001) (72)
- Development of the First Ultra-Potent “Capsaicinoid” Agonist at Transient Receptor Potential Vanilloid Type 1 (TRPV1) Channels and Its Therapeutic Potential (2005) (72)
- The levels of the endocannabinoid receptor CB2 and its ligand 2-arachidonoylglycerol are elevated in endometrial carcinoma. (2010) (72)
- A Gradient of 2-Arachidonoylglycerol Regulates Mouse Epididymal Sperm Cell Start-Up1 (2010) (72)
- Endocannabinoids : The Brain and Body's Marijuana and Beyond (2005) (72)
- New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosis (2006) (72)
- Forebrain-Specific Inactivation of Gq/G11 Family G Proteins Results in Age-Dependent Epilepsy and Impaired Endocannabinoid Formation (2006) (71)
- The role of the endocannabinoid system in Alzheimer's disease: facts and hypotheses. (2008) (71)
- The endocannabinoid system mediates aerobic exercise-induced antinociception in rats (2014) (71)
- Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men (2013) (70)
- Altered gut microbiota and endocannabinoid system tone in vitamin D deficiency-mediated chronic pain (2020) (70)
- The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels (2014) (69)
- Development of an activity-based probe and in silico design reveal highly selective inhibitors for diacylglycerol lipase-α in brain. (2013) (69)
- Spinal anandamide produces analgesia in neuropathic rats: Possible CB1- and TRPV1-mediated mechanisms (2012) (69)
- A brief history of cannabinoid and endocannabinoid pharmacology as inspired by the work of British scientists. (2006) (69)
- Arachidonic acid and eicosanoids as targets and effectors in second messenger interactions. (1995) (69)
- Bioactive long chain N-acylethanolamines in five species of edible bivalve molluscs. Possible implications for mollusc physiology and sea food industry. (1998) (68)
- Periaqueductal gray metabotropic glutamate receptor subtype 7 and 8 mediate opposite effects on amino acid release, rostral ventromedial medulla cell activities, and thermal nociception. (2007) (67)
- Inhibitory effect of the anorexic compound oleoylethanolamide on gastric emptying in control and overweight mice (2008) (67)
- Altered endocannabinoid signalling after a high-fat diet in Apoe−/− mice: relevance to adipose tissue inflammation, hepatic steatosis and insulin resistance (2011) (67)
- Orexin-A represses satiety-inducing POMC neurons and contributes to obesity via stimulation of endocannabinoid signaling (2016) (66)
- The dual blocker of FAAH/TRPV1 N-arachidonoylserotonin reverses the behavioral despair induced by stress in rats and modulates the HPA-axis. (2014) (66)
- Up-regulation of the endocannabinoid system in the uterus of leptin knockout (ob/ob) mice and implications for fertility. (2005) (66)
- Cannabimimetic fatty acid derivatives in cancer and inflammation. (2000) (66)
- Coronary vasomotor control in obesity and morbid obesity: contrasting flow responses with endocannabinoids, leptin, and inflammation. (2012) (66)
- Maternal dietary fat determines metabolic profile and the magnitude of endocannabinoid inhibition of the stress response in neonatal rat offspring. (2010) (66)
- Role and regulation of acylethanolamides in energy balance: focus on adipocytes and beta-cells. (2007) (66)
- At the Tip of an Iceberg: Prenatal Marijuana and Its Possible Relation to Neuropsychiatric Outcome in the Offspring (2016) (65)
- Overactivity of the intestinal endocannabinoid system in celiac disease and in methotrexate-treated rats (2007) (65)
- A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2‐arachidonoylglycerol with potential anti‐obesity effects (2013) (64)
- Two non-psychoactive cannabinoids reduce intracellular lipid levels and inhibit hepatosteatosis. (2015) (64)
- Anandamide as an intracellular messenger regulating ion channel activity (2005) (64)
- Synthesis and biological evaluation of [6]-gingerol analogues as transient receptor potential channel TRPV1 and TRPA1 modulators. (2012) (64)
- Bioactive prenylogous cannabinoid from fiber hemp (Cannabis sativa). (2011) (63)
- The sleep inducing factor oleamide is produced by mouse neuroblastoma cells. (1997) (63)
- Basal and Fasting/Refeeding‐regulated Tissue Levels of Endogenous PPAR‐α Ligands in Zucker Rats (2010) (63)
- CB1 Cannabinoid Receptors Couple to Focal Adhesion Kinase to Control Insulin Release* (2013) (63)
- Cannabimovone, a Cannabinoid with a Rearranged Terpenoid Skeleton from Hemp (2010) (62)
- Evidence for an endocannabinoid system in the central nervous system of the leech Hirudo medicinalis. (2001) (62)
- Anti‐inflammatory Effect of Palmitoylethanolamide on Human Adipocytes (2009) (62)
- Synthesis, cannabinoid receptor affinity, and molecular modeling studies of substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides. (2008) (62)
- New 1,8-naphthyridine and quinoline derivatives as CB2 selective agonists. (2007) (62)
- The effect of cannabichromene on adult neural stem/progenitor cells (2013) (62)
- The dual fatty acid amide hydrolase/TRPV1 blocker, N-arachidonoyl-serotonin, relieves carrageenan-induced inflammation and hyperalgesia in mice. (2010) (61)
- Bisphenol A Induces Fatty Liver by an Endocannabinoid-Mediated Positive Feedback Loop. (2016) (61)
- Biosynthesis and inactivation of endocannabinoids: relevance to their proposed role as neuromodulators. (1999) (61)
- A structure-activity relationship study on N-arachidonoyl-amino acids as possible endogenous inhibitors of fatty acid amide hydrolase. (2004) (61)
- Behavioral and molecular changes elicited by acute administration of SR141716 to Delta9-tetrahydrocannabinol-tolerant rats: an experimental model of cannabinoid abstinence. (2004) (61)
- Carbamoyl tetrazoles as inhibitors of endocannabinoid inactivation: a critical revisitation. (2008) (60)
- New N-arachidonoylserotonin analogues with potential "dual" mechanism of action against pain. (2007) (60)
- The 1,2,3-triazole ring as a peptido- and olefinomimetic element: discovery of click vanilloids and cannabinoids. (2007) (60)
- Halogenation of a capsaicin analogue leads to novel vanilloid TRPV1 receptor antagonists (2003) (60)
- The role of the endocannabinoid system in skeletal muscle and metabolic adaptations to exercise: potential implications for the treatment of obesity (2012) (59)
- Endocannabinoids Link Feeding State and Auditory Perception-Related Gene Expression (2004) (59)
- The Endocannabinoid System Protects Rat Glioma Cells Against HIV-1 Tat Protein-induced Cytotoxicity (2002) (59)
- Levels of endocannabinoids and palmitoylethanolamide and their pharmacological manipulation in chronic granulomatous inflammation in rats. (2010) (59)
- Investigations on the 4-quinolone-3-carboxylic acid motif. 2. Synthesis and structure-activity relationship of potent and selective cannabinoid-2 receptor agonists endowed with analgesic activity in vivo. (2008) (59)
- Metabolism of anandamide and 2-arachidonoylglycerol: An historical overview and some recent developments (2007) (59)
- Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain. (2016) (58)
- Effects of intra-ventrolateral periaqueductal grey palmitoylethanolamide on thermoceptive threshold and rostral ventromedial medulla cell activity. (2012) (58)
- Iron overload causes osteoporosis in thalassemia major patients through interaction with transient receptor potential vanilloid type 1 (TRPV1) channels (2014) (58)
- A multi-target approach for pain treatment: dual inhibition of fatty acid amide hydrolase and TRPV1 in a rat model of osteoarthritis (2015) (57)
- Endocannabinoids and neuropathic pain: focus on neuron–glia and endocannabinoid–neurotrophin interactions (2014) (57)
- Cannabinoid receptor type 1 and 2 expression in the skin of healthy dogs and dogs with atopic dermatitis. (2012) (56)
- Genetic deletion of monoacylglycerol lipase leads to impaired cannabinoid receptor CB1R signaling and anxiety‐like behavior (2015) (56)
- Semiplenamides A-G, fatty acid amides from a Papua New Guinea collection of the marine cyanobacterium Lyngbya semiplena. (2003) (55)
- The endovanilloid/endocannabinoid system: a new potential target for osteoporosis therapy. (2011) (55)
- Indole-2-carboxamides as allosteric modulators of the cannabinoid CB₁ receptor. (2012) (55)
- Anandamide as an intracellular messenger regulating ion channel activity. (2005) (55)
- The hypothalamic levels of the endocannabinoid, anandamide, peak immediately before the onset of puberty in female rats. (2002) (55)
- Enhanced cognitive performance of dopamine D3 receptor "knock-out" mice in the step-through passive-avoidance test: assessing the role of the endocannabinoid/endovanilloid systems. (2010) (54)
- Short- and long-term plasticity of the endocannabinoid system in neuropsychiatric and neurological disorders. (2007) (54)
- A brief history of cannabinoid and endocannabinoid pharmacology as inspired by the work of British scientists. (2006) (53)
- Rimonabant Precipitates Anxiety in Rats Withdrawn from Palatable Food: Role of the Central Amygdala (2013) (53)
- Endocannabinoid chemical biology: a tool for the development of novel therapies. (2009) (53)
- Acute inhibition of diacylglycerol lipase blocks endocannabinoid‐mediated retrograde signalling: evidence for on‐demand biosynthesis of 2‐arachidonoylglycerol (2013) (53)
- The analgesic effect of N-arachidonoyl-serotonin, a FAAH inhibitor and TRPV1 receptor antagonist, associated with changes in rostral ventromedial medulla and locus coeruleus cell activity in rats (2008) (53)
- The taming of capsaicin. Reversal of the vanilloid activity of N-acylvanillamines by aromatic iodination. (2005) (52)
- Endocannabinoid synthesis and degradation, and their regulation in the framework of energy balance. (2006) (52)
- Taste-guided identification of high potency TRPA1 agonists from Perilla frutescens. (2009) (52)
- The effects of anandamide on memory consolidation in mice involve both D1and D2 dopamine receptors (1997) (52)
- Functional interaction between TRPV1 and mu-opioid receptors in the descending antinociceptive pathway activates glutamate transmission and induces analgesia. (2009) (51)
- Selection of alternative G-mediated signaling pathways at the dopamine D2 receptor by protein kinase C (1993) (51)
- Endocannabinoid regulation in white and brown adipose tissue following thermogenic activation (2016) (51)
- Fatty Acid Amide Hydrolase (FAAH), Acetylcholinesterase (AChE), and Butyrylcholinesterase (BuChE): Networked Targets for the Development of Carbamates as Potential Anti-Alzheimer's Disease Agents. (2016) (51)
- Obesity Affects the Microbiota–Gut–Brain Axis and the Regulation Thereof by Endocannabinoids and Related Mediators (2020) (51)
- Highly Selective, Reversible Inhibitor Identified by Comparative Chemoproteomics Modulates Diacylglycerol Lipase Activity in Neurons. (2015) (51)
- Occurrence and possible biological role of the endocannabinoid system in the sea squirt Ciona intestinalis (2005) (50)
- Investigations on the 4-quinolone-3-carboxylic acid motif. 4. Identification of new potent and selective ligands for the cannabinoid type 2 receptor with diverse substitution patterns and antihyperalgesic effects in mice. (2011) (50)
- 2-Arylbenzofuran-based molecules as multipotent Alzheimer's disease modifying agents. (2012) (50)
- The role of the CB1 cannabinoid receptor and its endogenous ligands, anandamide and 2-arachidonoylglycerol, in amphetamine-induced behavioural sensitization (2008) (50)
- Comparative biology of the endocannabinoid system possible role in the immune response. (2000) (50)
- The CB1 cannabinoid receptor antagonist AM251 attenuates amphetamine-induced behavioural sensitization while causing monoamine changes in nucleus accumbens and hippocampus (2008) (50)
- Identification and characterization of phytocannabinoids as novel dual PPARα/γ agonists by a computational and in vitro experimental approach. (2019) (49)
- Pharmacological inhibition of MAGL attenuates experimental colon carcinogenesis (2017) (49)
- Arachidonic acid and eicosanoids as targets and effectors in second messenger interactions. (1995) (49)
- Functional lipidomics. Calcium-independent activation of endocannabinoid/endovanilloid lipid signalling in sensory neurons by protein kinases C and A and thrombin (2008) (49)
- Responses of peripheral endocannabinoids and endocannabinoid-related compounds to hedonic eating in obesity (2016) (49)
- Cannabinoid properties of methylfluorophosphonate analogs. (2000) (49)
- Peripubertal cannabidiol treatment rescues behavioral and neurochemical abnormalities in the MAM model of schizophrenia (2019) (49)
- N-Acylvanillamides: development of an expeditious synthesis and discovery of new acyl templates for powerful activation of the vanilloid receptor. (2002) (49)
- Synthesis and biological evaluation of new potential inhibitors of N-acylethanolamine hydrolyzing acid amidase. (2010) (48)
- Acute Resistance Exercise Induces Antinociception by Activation of the Endocannabinoid System in Rats (2014) (48)
- The Endocannabinoid 2-Arachidonoyl-Glycerol Controls Odor Sensitivity in Larvae of Xenopus laevis (2010) (48)
- Deficiency of cannabinoid receptor of type 2 worsens renal functional and structural abnormalities in streptozotocin-induced diabetic mice. (2014) (48)
- Role of endocannabinoids and endovanilloids in Ca2+ signalling. (2009) (48)
- Oral Ultramicronized Palmitoylethanolamide: Plasma and Tissue Levels and Spinal Anti-hyperalgesic Effect (2018) (47)
- Cannabinoid CB1 receptor antagonism prevents neurochemical and behavioural deficits induced by chronic phencyclidine. (2011) (47)
- Cannabinoid CB1 receptor stimulation affords neuroprotection in MPTP-induced neurotoxicity by attenuating S100B up-regulation in vitro (2007) (47)
- Germ-free mice exhibit profound gut microbiota-dependent alterations of intestinal endocannabinoidome signaling. (2020) (47)
- Cannabinoid CB1 receptor expression in relation to visceral adipose depots, endocannabinoid levels, microvascular damage, and the presence of the Cnr1 A3813G variant in humans. (2010) (47)
- Role of endocannabinoids and endovanilloids in Ca2+ signalling. (2009) (47)
- Endocannabinoids: Some Like it Fat (and Sweet Too) (2008) (47)
- Adelmidrol, a palmitoylethanolamide analogue, reduces chronic inflammation in a carrageenin-granuloma model in rats (2008) (47)
- Endocannabinoid signaling in the brain: biosynthetic mechanisms in the limelight. (2011) (47)
- The non-euphoric phytocannabinoid cannabidivarin counteracts intestinal inflammation in mice and cytokine expression in biopsies from UC pediatric patients. (2019) (46)
- Circulating endocannabinoids in insulin sensitive vs. Insulin resistant obese postmenopausal women. A MONET group study (2014) (46)
- Palmitoylethanolamide reduces inflammation and itch in a mouse model of contact allergic dermatitis. (2016) (46)
- Modulation of mouse gastrointestinal motility by allyl isothiocyanate, a constituent of cruciferous vegetables (Brassicaceae): evidence for TRPA1‐independent effects (2012) (46)
- Regulation of hypothalamic endocannabinoid levels by neuropeptides and hormones involved in food intake and metabolism: Insulin and melanocortins (2008) (46)
- Cisplatin increases brain 2-arachidonoylglycerol (2-AG) and concomitantly reduces intestinal 2-AG and anandamide levels in the least shrew (2005) (46)
- Effects of non‐euphoric plant cannabinoids on muscle quality and performance of dystrophic mdx mice (2018) (45)
- Kavalactones and the endocannabinoid system: the plant-derived yangonin is a novel CB₁ receptor ligand. (2012) (45)
- Anandamide-derived Prostamide F2α Negatively Regulates Adipogenesis (2013) (45)
- The Developmentally Regulated Avian Ch21 Lipocalin Is an Extracellular Fatty Acid-binding Protein* (1996) (45)
- The Expanded Endocannabinoid System/Endocannabinoidome as a Potential Target for Treating Diabetes Mellitus (2019) (45)
- Possible Anandamide and Palmitoylethanolamide involvement in human stroke (2010) (45)
- Capsaicin-like effects of N-arachidonoyl-dopamine in the isolated guinea pig bronchi and urinary bladder. (2003) (44)
- DAG Lipase Involvement in Depolarization-Induced Suppression of Inhibition: Does Endocannabinoid Biosynthesis Always Meet the Demand? (2010) (44)
- Negative Regulation of Leptin-induced Reactive Oxygen Species (ROS) Formation by Cannabinoid CB1 Receptor Activation in Hypothalamic Neurons (2015) (44)
- Altered responses of dopamine D3 receptor null mice to excitotoxic or anxiogenic stimuli: Possible involvement of the endocannabinoid and endovanilloid systems (2009) (44)
- Design, synthesis, and binding studies of new potent ligands of cannabinoid receptors. (2005) (43)
- 2-Pentadecyl-2-Oxazoline, the Oxazoline of Pea, Modulates Carrageenan-Induced Acute Inflammation (2017) (43)
- Endocannabinoids and related fatty acid amides, and their regulation, in the salivary glands of the lone star tick. (2003) (43)
- Investigations on the 4-quinolone-3-carboxylic acid motif. 3. Synthesis, structure-affinity relationships, and pharmacological characterization of 6-substituted 4-quinolone-3-carboxamides as highly selective cannabinoid-2 receptor ligands. (2010) (43)
- Why endocannabinoids are not all alike (2008) (43)
- Arvanil inhibits T lymphocyte activation and ameliorates autoimmune encephalomyelitis (2006) (42)
- Diacylglycerol Lipase Is Not Involved in Depolarization-Induced Suppression of Inhibition at Unitary Inhibitory Connections in Mouse Hippocampus (2010) (42)
- Analysis of the "endocannabinoidome" in peripheral tissues of obese Zucker rats. (2013) (42)
- Lipids as regulators of the activity of transient receptor potential type V1 (TRPV1) channels. (2005) (42)
- Chronic exposure to cannabinoids during adolescence causes long‐lasting behavioral deficits in adult mice (2016) (42)
- CB2-Selective Cannabinoid Receptor Ligands: Synthesis, Pharmacological Evaluation, and Molecular Modeling Investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides (2014) (42)
- Orexin-A and Endocannabinoid Activation of the Descending Antinociceptive Pathway Underlies Altered Pain Perception in Leptin Signaling Deficiency (2016) (41)
- A TRPV1‐to‐secretagogin regulatory axis controls pancreatic β‐cell survival by modulating protein turnover (2017) (40)
- N-palmitoyl-vanillamide (palvanil) is a non-pungent analogue of capsaicin with stronger desensitizing capability against the TRPV1 receptor and anti-hyperalgesic activity. (2011) (40)
- Abstract 215: Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1. (2013) (40)
- Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: an investigation of the 1,8-naphthyridin-2(1H)-one scaffold. (2012) (40)
- Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture (2015) (40)
- Increased levels of palmitoylethanolamide and other bioactive lipid mediators and enhanced local mast cell proliferation in canine atopic dermatitis (2014) (39)
- Platelet-rich plasma exerts antinociceptive activity by a peripheral endocannabinoid-related mechanism. (2013) (39)
- The anandamide membrane transporter inhibitor, VDM-11, modulates sleep and c-Fos expression in the rat brain (2008) (39)
- Dual therapy targeting the endocannabinoid system prevents experimental diabetic nephropathy (2017) (39)
- A re‐evaluation of 9‐HODE activity at TRPV1 channels in comparison with anandamide: enantioselectivity and effects at other TRP channels and in sensory neurons (2012) (38)
- CB(1) receptor antagonism: biological basis for metabolic effects. (2008) (38)
- Effect of maternal under-nutrition on pup body weight and hypothalamic endocannabinoid levels (2003) (38)
- Endocannabinoids Generated by Ca2+ or by Metabotropic Glutamate Receptors Appear to Arise from Different Pools of Diacylglycerol Lipase (2011) (38)
- Dietary fatty acid intake and gut microbiota determine circulating endocannabinoidome signaling beyond the effect of body fat (2020) (38)
- Anandamide, an endogenous cannabinomimetic substance, modulates rat brain protein kinase C in vitro. (1995) (38)
- Changes in the endocannabinoid signaling system in CNS structures of TDP-43 transgenic mice: relevance for a neuroprotective therapy in TDP-43-related disorders (2015) (38)
- Aquatic invertebrates open up new perspectives in eicosanoid research: biosynthesis and bioactivity. (1994) (37)
- Elevation of Plasma 2-Arachidonoylglycerol Levels in Alzheimer's Disease Patients as a Potential Protective Mechanism against Neurodegenerative Decline. (2015) (37)
- The gut microbiome, endocannabinoids and metabolic disorders. (2020) (37)
- Cannabinomimetic lipid from a marine cyanobacterium. (2011) (37)
- Rational design, synthesis, and pharmacological properties of new 1,8-naphthyridin-2(1H)-on-3-carboxamide derivatives as highly selective cannabinoid-2 receptor agonists. (2009) (36)
- Exploiting Nanotechnologies and TRPV1 Channels to Investigate the Putative Anandamide Membrane Transporter (2010) (36)
- Inhibition of basal and ultraviolet B-induced melanogenesis by cannabinoid CB1 receptors: a keratinocyte-dependent effect (2011) (36)
- Brain TRPV1: a depressing TR(i)P down memory lane? (2008) (36)
- Therapy with a Selective Cannabinoid Receptor Type 2 Agonist Limits Albuminuria and Renal Injury in Mice with Type 2 Diabetic Nephropathy (2015) (36)
- Antinociceptive effects of tetrazole inhibitors of endocannabinoid inactivation: cannabinoid and non‐cannabinoid receptor‐mediated mechanisms (2008) (36)
- Anandamide and AM251, via water, modulate food intake at central and peripheral level in fish. (2010) (36)
- Taste sensitivity to 6-n-propylthiouracil is associated with endocannabinoid plasma levels in normal-weight individuals. (2013) (36)
- Rapid and Concomitant Gut Microbiota and Endocannabinoidome Response to Diet-Induced Obesity in Mice (2019) (36)
- Diacerein is a potent and selective inhibitor of palmitoylethanolamide inactivation with analgesic activity in a rat model of acute inflammatory pain. (2015) (35)
- Non-psychotropic analgesic drugs from the endocannabinoid system: "magic bullet" or "multiple-target" strategies? (2013) (35)
- The First Dual ChE/FAAH Inhibitors: New Perspectives for Alzheimer's Disease? (2012) (35)
- Cannabidivarin completely rescues cognitive deficits and delays neurological and motor defects in male Mecp2 mutant mice (2019) (35)
- The endocannabinoid system in renal cells: regulation of Na+ transport by CB1 receptors through distinct cell signalling pathways (2015) (35)
- Homology modeling in tandem with 3D-QSAR analyses: a computational approach to depict the agonist binding site of the human CB2 receptor. (2011) (35)
- Arvanil, a hybrid endocannabinoid and vanilloid compound, behaves as an antihyperkinetic agent in a rat model of Huntington's disease (2005) (35)
- Beneficial Effects of Akkermansia muciniphila Are Not Associated with Major Changes in the Circulating Endocannabinoidome but Linked to Higher Mono-Palmitoyl-Glycerol Levels as New PPARα Agonists (2021) (34)
- Control of experimental spasticity by targeting the degradation of endocannabinoids using selective fatty acid amide hydrolase inhibitors (2013) (34)
- CB1 receptor activation induces intracellular Ca2+ mobilization and 2-arachidonoylglycerol release in rodent spinal cord astrocytes (2018) (34)
- A novel multifunctional metabolic pathway in a marine mollusc leads to unprecedented prostaglandin derivatives (prostaglandin 1,15-lactones). (1991) (33)
- Effects of palmitoylethanolamide on the cutaneous allergic inflammatory response in Ascaris hypersensitive Beagle dogs. (2012) (33)
- Inhibiting endocannabinoid biosynthesis: a novel approach to the treatment of constipation (2015) (33)
- Genetic and pharmacological regulation of the endocannabinoid CB1 receptor in Duchenne muscular dystrophy (2018) (33)
- Anticipatory and consummatory effects of (hedonic) chocolate intake are associated with increased circulating levels of the orexigenic peptide ghrelin and endocannabinoids in obese adults (2015) (33)
- [The endocannabinoid system as a target for the development of new drugs for cancer therapy]. (2003) (33)
- Deranged endocannabinoid responses to hedonic eating in underweight and recently weight-restored patients with anorexia nervosa. (2015) (32)
- Palmitoylethanolamide counteracts substance P-induced mast cell activation in vitro by stimulating diacylglycerol lipase activity (2019) (32)
- Biosynthesis, structure and biological activity of hydroxyeicosatetraenoic acids in Hydra vulgaris. (1993) (32)
- Palmitoylethanolamide Supplementation during Sensitization Prevents Airway Allergic Symptoms in the Mouse (2017) (32)
- Participants with Normal Weight or with Obesity Show Different Relationships of 6-n-Propylthiouracil (PROP) Taster Status with BMI and Plasma Endocannabinoids (2017) (32)
- Dose‐Specific Effects of Di‐Isononyl Phthalate on the Endocannabinoid System and on Liver of Female Zebrafish (2017) (32)
- Minor Bioactive Polyacetylenes from Petrosia ficiformis (1990) (32)
- Ultra-micronized palmitoylethanolamide rescues the cognitive decline-associated loss of neural plasticity in the neuropathic mouse entorhinal cortex-dentate gyrus pathway (2019) (32)
- High molecular weight polyacetylenes from Petrosia ficiformis: Further structural analysis and biological activity (1989) (31)
- Synthesis and biological evaluation of piperazinyl carbamates and ureas as fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channel dual ligands. (2009) (31)
- Elevated Systemic Levels of Endocannabinoids and Related Mediators Across the Menstrual Cycle in Women With Endometriosis (2016) (31)
- Participation of Prostaglandin E2 in Dopamine D2 Receptor‐Dependent Potentiation of Arachidonic Acid Release (1992) (31)
- Oxidative metabolism of lipoamino acids and vanilloids by lipoxygenases and cyclooxygenases. (2007) (31)
- New quinolone- and 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity. (2015) (31)
- Discovery of glycine sulfonamides as dual inhibitors of sn-1-diacylglycerol lipase α and α/β-hydrolase domain 6. (2014) (31)
- Endocannabinoids, feeding and suckling – from our perspective (2006) (30)
- Three-dimensional quantitative structure-selectivity relationships analysis guided rational design of a highly selective ligand for the cannabinoid receptor 2. (2011) (30)
- 3-Ylidenephthalides as a new class of transient receptor potential channel TRPA1 and TRPM8 modulators. (2013) (30)
- Polypharmacology Shakes Hands with Complex Aetiopathology. (2015) (30)
- (-)-Menthylamine derivatives as potent and selective antagonists of transient receptor potential melastatin type-8 (TRPM8) channels. (2010) (30)
- Altered dopamine D3 receptor gene expression in MAM model of schizophrenia is reversed by peripubertal cannabidiol treatment. (2020) (29)
- N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice (2019) (29)
- Disruption of the gonadal endocannabinoid system in zebrafish exposed to diisononyl phthalate. (2018) (29)
- Effects of curcumin and curcumin analogues on TRP channels. (2017) (29)
- New tetrazole-based selective anandamide uptake inhibitors. (2008) (29)
- Effect of the Cannabinoid Receptor-1 antagonist SR141716A on human adipocyte inflammatory profile and differentiation (2011) (28)
- α-and γ-Pyrone-poly·propionates from the mediterranean ascoglossan mollusc ercolania funerea (1992) (28)
- Inhibitors of endocannabinoid breakdown for pain: Not so FA(AH)cile, after all (2012) (28)
- Anandamide serves two masters in the brain (2010) (28)
- Piperazinyl carbamate fatty acid amide hydrolase inhibitors and transient receptor potential channel modulators as "dual-target" analgesics. (2013) (28)
- Polymorphism rs1761667 in the CD36 Gene Is Associated to Changes in Fatty Acid Metabolism and Circulating Endocannabinoid Levels Distinctively in Normal Weight and Obese Subjects (2017) (27)
- Cannabinoid CB1 receptor elevation of intracellular calcium in neuroblastoma SH-SY5Y cells: interactions with muscarinic and delta-opioid receptors. (2009) (27)
- Structure-activity relationships of thiazole and benzothiazole derivatives as selective cannabinoid CB2 agonists with in vivo anti-inflammatory properties. (2019) (27)
- Chemical characterisation of oxidative degradation products of Δ9-THC (2010) (27)
- Circulating Endocannabinoids and the Polymorphism 385C>A in Fatty Acid Amide Hydrolase (FAAH) Gene May Identify the Obesity Phenotype Related to Cardiometabolic Risk: A Study Conducted in a Brazilian Population of Complex Interethnic Admixture (2015) (27)
- Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 7. Synthesis and Pharmacological Evaluation of 4-Quinolone-3-carboxamides and 4-Hydroxy-2-quinolone-3-carboxamides as High Affinity Cannabinoid Receptor 2 (CB2R) Ligands with Improved Aqueous Solubility. (2016) (27)
- Design, synthesis, and pharmacological characterization of indol-3-ylacetamides, indol-3-yloxoacetamides, and indol-3-ylcarboxamides: potent and selective CB2 cannabinoid receptor inverse agonists. (2012) (27)
- The CB1/VR1 agonist arvanil induces apoptosis through an FADD/caspase‐8‐dependent pathway (2003) (26)
- Cyercenes, novel pyrones from the ascoglossan molluscCyerce cristallina. Tissue distribution, biosynthesis and possible involvement in defense and regenerative processes (1991) (26)
- Endocrine disruptors in the diet of male Sparus aurata: Modulation of the endocannabinoid system at the hepatic and central level by Di-isononyl phthalate and Bisphenol A. (2018) (26)
- In vitro and in vivo pharmacological characterization of two novel selective cannabinoid CB(2) receptor inverse agonists. (2010) (26)
- Modulation of thermo-transient receptor potential (thermo-TRP) channels by thymol-based compounds. (2012) (26)
- Treatment with the GPR55 antagonist CID16020046 increases neutrophil activation in mouse atherogenesis (2016) (25)
- Fish Oil, Cannabidiol and the Gut Microbiota: An Investigation in a Murine Model of Colitis (2020) (25)
- Distinct Temporal Fingerprint for Cyclic Adenosine Monophosphate (cAMP) Signaling of Indole-2-carboxamides as Allosteric Modulators of the Cannabinoid Receptors. (2015) (25)
- Protective effect of palmitoylethanolamide in a rat model of cystitis. (2015) (25)
- First “hybrid” ligands of vanilloid TRPV1 and cannabinoid CB2 receptors and non‐polyunsaturated fatty acid‐derived CB2‐selective ligands (2006) (25)
- Biosynthesis and inactivation of endocannabinoids: relevance to their proposed role as neuromodulators. (1999) (25)
- Prostamide F2α receptor antagonism combined with inhibition of FAAH may block the pro‐inflammatory mediators formed following selective FAAH inhibition (2014) (25)
- Sesquiterpenoids from Common Ragweed (Ambrosia artemisiifolia L.), an invasive biological polluter (2012) (24)
- Some like it pungent and vile. TRPA1 as a molecular target for the malodorous vinyl disulfides from asafoetida. (2013) (24)
- The Synthesis of N-Vanillyl-arachidonoyl-amide (Arvanil) and its Analogs: An Improved Procedure for the Synthesis of the Key Synthon Methyl 14-Hydroxy-(all-cis)-5,8,11-tetradecatrienoate (2000) (24)
- CB1 Cannabinoid Receptors Mediate Cognitive Deficits and Structural Plasticity Changes During Nicotine Withdrawal (2017) (24)
- Endovanilloid control of pain modulation by the rostroventromedial medulla in an animal model of diabetic neuropathy (2016) (24)
- Effects of metabolites of the analgesic agent dipyrone (metamizol) on rostral ventromedial medulla cell activity in mice. (2015) (24)
- Role of N-Arachidonoyl-Serotonin (AA-5-HT) in Sleep-Wake Cycle Architecture, Sleep Homeostasis, and Neurotransmitters Regulation (2017) (24)
- Analogues of perillaketone as highly potent agonists of TRPA1 channel. (2013) (24)
- v-K-ras leads to preferential farnesylation of p21(ras) in FRTL-5 cells: multiple interference with the isoprenoid pathway. (1998) (24)
- Cannabinoids and schizophrenia: therapeutic prospects. (2014) (23)
- The multiplicity of spinal AA-5-HT anti-nociceptive action in a rat model of neuropathic pain. (2016) (23)
- Effects of chronic exercise on the endocannabinoid system in Wistar rats with high-fat diet-induced obesity (2016) (23)
- Glutamate spillover drives endocannabinoid production and inhibits GABAergic transmission in the Substantia Nigra pars compacta (2014) (23)
- Adelmidrol increases the endogenous concentrations of palmitoylethanolamide in canine keratinocytes and down-regulates an inflammatory reaction in an in vitro model of contact allergic dermatitis. (2016) (23)
- Discovery of novel Tetrahydrobenzo[b]thiophene and pyrrole based scaffolds as potent and selective CB2 receptor ligands: The structural elements controlling binding affinity, selectivity and functionality. (2016) (23)
- Mechanisms of HIV-1 Inhibition by the Lipid Mediator N-Arachidonoyldopamine1 (2005) (23)
- Important role of endocannabinoid signaling in the development of functional vision and locomotion in zebrafish (2016) (22)
- Fishing for Targets of Alien Metabolites: A Novel Peroxisome Proliferator-Activated Receptor (PPAR) Agonist from a Marine Pest (2018) (22)
- Exposure to Allergen Causes Changes in NTS Neural Activities after Intratracheal Capsaicin Application, in Endocannabinoid Levels and in the Glia Morphology of NTS (2015) (22)
- Early Low-Fat Diet Enriched With Linolenic Acid Reduces Liver Endocannabinoid Tone and Improves Late Glycemic Control After a High-Fat Diet Challenge in Mice (2016) (22)
- Endocannabinoids: An appetite for fat (2011) (22)
- The anandamide membrane transporter. Structure-activity relationships of anandamide and oleoylethanolamine analogs with phenyl rings in the polar head group region. (2004) (22)
- Crosstalk between the transcriptional regulation of dopamine D2 and cannabinoid CB1 receptors in perinatal Δ9-tetrahydrocannabinol occurs in schizophrenia: analyses in patients and in animal model of the disease. (2020) (22)
- Endocannabinoid hydrolysis inhibition unmasks that unsaturated fatty acids induce a robust biosynthesis of 2‐arachidonoyl‐glycerol and its congeners in human myeloid leukocytes (2020) (22)
- Characterization of endocannabinoids and related acylethanolamides in the synovial fluid of dogs with osteoarthritis: a pilot study (2017) (22)
- Anticonvulsive Properties of Cannabidiol in a Model of Generalized Seizure Are Transient Receptor Potential Vanilloid 1 Dependent (2020) (22)
- Effect of chirality and lipophilicity in the functional activity of evodiamine and its analogues at TRPV1 channels (2014) (22)
- Pure Δ9-tetrahydrocannabivarin and a Cannabis sativa extract with high content in Δ9-tetrahydrocannabivarin inhibit nitrite production in murine peritoneal macrophages. (2016) (21)
- Desulfohaplosamate, a new phosphate-containing steroid from Dasychalina sp., is a selective cannabinoid CB2 receptor ligand (2011) (21)
- Oxyhomologues of anandamide and related endolipids: chemoselective synthesis and biological activity. (2006) (21)
- Palvanil, a non-pungent capsaicin analogue, inhibits inflammatory and neuropathic pain with little effects on bronchopulmonary function and body temperature. (2012) (21)
- Rimonabant in rats with a metabolic syndrome: good news after the depression (2008) (21)
- Development of the first potential covalent inhibitors of anandamide cellular uptake. (2006) (20)
- Role of Endocannabinoids and Cannabinoid-1 Receptors in Cerebrocortical Blood Flow Regulation (2013) (20)
- Alterations of brain endocannabinoidome signaling in germ-free mice. (2020) (20)
- The endocannabinoid and endovanilloid systems and their interactions in neuropathic pain (2006) (20)
- Evaluation of the endogenous cannabinoid system in mediating the behavioral effects of dipyrone (metamizol) in mice (2012) (20)
- Combined CoMFA and CoMSIA 3D‐QSAR study of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor (2017) (20)
- Possible involvement of arachidonic acid and eicosanoids in metamorphic events in Hydractinia echinata (Coelenterata; Hydrozoa). (1994) (20)
- Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment. (2019) (20)
- Investigations on the 4-quinolone-3-carboxylic acid motif. 6. Synthesis and pharmacological evaluation of 7-substituted quinolone-3-carboxamide derivatives as high affinity ligands for cannabinoid receptors. (2012) (20)
- Gut feelings about the endocannabinoid system (2011) (20)
- Possible involvement of endocannabinoids in the increase of morphine consumption in maternally deprived rat (2013) (20)
- Mooreamide A: A Cannabinomimetic Lipid from the Marine Cyanobacterium Moorea bouillonii (2014) (20)
- The administration of endocannabinoid uptake inhibitors OMDM-2 or VDM-11 promotes sleep and decreases extracellular levels of dopamine in rats (2013) (20)
- Biosynthesis of 2-arachidonoyl-glycerol, a novel cannabimimetic eicosanoid, in mouse neuroblastoma cells. (1997) (19)
- Life-long epigenetic programming of cortical architecture by maternal ‘Western’ diet during pregnancy (2019) (19)
- Endocannabinoid modulation in the olfactory epithelium. (2010) (19)
- Peripheral Endocannabinoid Responses to Hedonic Eating in Binge-Eating Disorder (2017) (19)
- The endocannabinoidome as a substrate for noneuphoric phytocannabinoid action and gut microbiome dysfunction in neuropsychiatric disorders (2020) (19)
- Synthesis, biological activity and molecular modeling of new biphenylic carboxamides as potent and selective CB2 receptor ligands. (2015) (19)
- The endogenous cannabimimetic eicosanoid, anandamide, induces arachidonate release in J774 mouse macrophages. (1997) (19)
- Lipidomic methodologies applicable to the study of endocannabinoids and related compounds: Endocannabinoidomics (2009) (18)
- Effect of acyclic monoterpene alcohols and their derivatives on TRP channels. (2014) (18)
- Allodynia Lowering Induced by Cannabinoids and Endocannabinoids (ALICE) (2017) (18)
- Synthesis, binding assays, cytotoxic activity and docking studies of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor. (2016) (18)
- Manipulation of Dietary Amino Acids Prevents and Reverses Obesity in Mice Through Multiple Mechanisms That Modulate Energy Homeostasis (2020) (18)
- Anandamide and decidual remodelling: COX-2 oxidative metabolism as a key regulator. (2015) (18)
- The Involvement of the Endocannabinoid System in the Peripheral Antinociceptive Action of Ketamine. (2017) (18)
- Effects of BPA on zebrafish gonads: Focus on the endocannabinoid system. (2020) (18)
- Phytocannabinoids promote viability and functional adipogenesis of bone marrow-derived mesenchymal stem cells through different molecular targets. (2020) (18)
- Synthesis of novel 2-(1-adamantanylcarboxamido)thiophene derivatives. Selective cannabinoid type 2 (CB2) receptor agonists as potential agents for the treatment of skin inflammatory disease. (2019) (18)
- Endocannabinoids: An appetite for fat (2011) (18)
- Overlapping Distribution of Orexin and Endocannabinoid Receptors and Their Functional Interaction in the Brain of Adult Zebrafish (2018) (18)
- Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes. (2009) (18)
- New horizons on the role of cannabinoid CB1 receptors in palatable food intake, obesity and related dysmetabolism. (2014) (18)
- Play an ADAGIO with a STRADIVARIUS: the right patient for CB1 receptor antagonists? (2008) (17)
- Leucettamols, Bifunctionalized Marine Sphingoids, Act as Modulators of TRPA1 and TRPM8 Channels (2012) (17)
- Dopamine D2 receptor signaling via the arachidonic acid cascade: modulation by cAMP-dependent protein kinase A and prostaglandin E2. (1993) (17)
- Polyunsaturated-fatty-acid oxidation in Hydra: regioselectivity, substrate-dependent enantioselectivity and possible biological role. (1994) (17)
- Iodinated N-Acylvanillamines: Potential “Multiple-Target” Anti-Inflammatory Agents Acting via the Inhibition of T-Cell Activation and Antagonism at Vanilloid TRPV1 Channels (2006) (17)
- Palmitoylethanolamide: biochemistry, pharmacology and therapeutic use of a pleiotropic anti-inflammatory lipid mediator. (2013) (17)
- Anti-tumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma (2006) (17)
- Effects of diisononyl phthalate (DiNP) on the endocannabinoid and reproductive systems of male gilthead sea bream (Sparus aurata) during the spawning season (2019) (16)
- Orexin-A Prevents Lipopolysaccharide-Induced Neuroinflammation at the Level of the Intestinal Barrier (2019) (16)
- Anandamide interferes with human endometrial stromal-derived cell differentiation: An effect dependent on inhibition of cyclooxygenase-2 expression and prostaglandin E2 release. (2016) (16)
- Biaryl tetrazolyl ureas as inhibitors of endocannabinoid metabolism: modulation at the N-portion and distal phenyl ring. (2013) (16)
- Design, synthesis, binding, and molecular modeling studies of new potent ligands of cannabinoid receptors. (2007) (16)
- Systemic administration of serotonin exacerbates abdominal pain and colitis via interaction with the endocannabinoid system (2019) (16)
- Hepatic NAPE-PLD Is a Key Regulator of Liver Lipid Metabolism (2020) (16)
- Endocannabinoid Tone Regulates Human Sebocyte Biology. (2018) (16)
- Social defeat leads to changes in the endocannabinoid system: An overexpression of calreticulin and motor impairment in mice (2016) (15)
- Enantiospecific synthesis of bioactive hydroxyeicosatetraenoic acids (HETEs) in Hydra magnipapillata. (1994) (15)
- Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells (2016) (15)
- Efficacy of combined therapy with fish oil and phytocannabinoids in murine intestinal inflammation (2020) (15)
- Reversal of albuminuria by combined AM6545 and perindopril therapy in experimental diabetic nephropathy (2018) (15)
- Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain (2018) (15)
- 1,2-Dihydro-2-oxopyridine-3-carboxamides: the C-5 substituent is responsible for functionality switch at CB2 cannabinoid receptor. (2014) (15)
- Role of Bisphenol A on the Endocannabinoid System at central and peripheral levels: Effects on adult female zebrafish. (2018) (14)
- Anandamide acts as an intracellular messenger amplifying Ca2+ influx via TRPV1 channels (2005) (14)
- Goldfish CB1 mRNA expression is affected by fasting and anandamide administration (2009) (14)
- In vitro and in vivo pharmacology of synthetic olivetol‐ or resorcinol‐derived cannabinoid receptor ligands (2006) (14)
- New analgesics synthetically derived from the paracetamol metabolite N-(4-hydroxyphenyl)-(5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-enamide. (2008) (14)
- Mgll Knockout Mouse Resistance to Diet-Induced Dysmetabolism Is Associated with Altered Gut Microbiota (2020) (14)
- Role of the endocannabinoid system in obesity induced by neuropeptide Y overexpression in noradrenergic neurons (2015) (14)
- Endocannabinoids and multiple sclerosis: a blessing from the 'inner bliss'? (2000) (14)
- New resorcinol-anandamide "hybrids" as potent cannabinoid receptor ligands endowed with antinociceptive activity in vivo. (2009) (14)
- Effects of Dietary Bisphenol A on the Reproductive Function of Gilthead Sea Bream (Sparus aurata) Testes (2019) (13)
- Discovery of non-electrophilic capsaicinoid-type TRPA1 ligands. (2015) (13)
- Cannabidiol in sport : ergogenic or else? (2020) (13)
- The Endocannabinoid System – Back to the Scene of Cardiometabolic Risk Factors Control? (2014) (13)
- Preparation and characterization of Δ9-tetrahydrocannabinol-loaded biodegradable polymeric microparticles and their antitumoral efficacy on cancer cell lines (2013) (13)
- Analysis of endocannabinoid signaling elements and related proteins in lymphocytes of patients with Dravet syndrome (2016) (13)
- TRPA1 channels as targets for resveratrol and related stilbenoids. (2016) (13)
- Structure-activity relationships of the ultrapotent vanilloid resiniferatoxin (RTX): the homovanillyl moiety. (2007) (13)
- Novel sterically hindered cannabinoid CB1 receptor ligands. (2008) (13)
- Non-CB1, Non-CB2 Receptors for Endocannabinoids (2005) (13)
- The time course of erythrocyte membrane fatty acid concentrations during and after treatment of non-human primates with increasing doses of an omega-3 rich phospholipid preparation derived from krill-oil (2017) (13)
- Germ-free mice exhibit profound gut microbiota-dependent alterations of intestinal endocannabinoidome signaling[S] (2019) (13)
- Synthesis, binding studies and molecular modeling of novel cannabinoid receptor ligands. (2010) (13)
- Prostaglandin F-1,15-lactone fatty acyl esters: a prostaglandin lactone pathway branch developed during the reproduction and early larval stages of a marine mollusc (1992) (13)
- Formation of OX-1R/CB1R heteromeric complexes in embryonic mouse hypothalamic cells: Effect on intracellular calcium, 2-arachidonoyl-glycerol biosynthesis and ERK phosphorylation. (2016) (12)
- Platelet activating factor-mediated leukotriene biosynthesis in rat lungs: effect of prostaglandins E1 and F1a (1987) (12)
- Rapid combinatorial access to a library of 1,5-disubstituted-3-indole-N-alkylacetamides as CB2 receptor ligands. (2009) (12)
- Anandamide drives cell cycle progression through CB1 receptors in a rat model of synchronized liver regeneration (2015) (12)
- Plasma palmitoylethanolamide (PEA) as a potential biomarker for impaired coronary function. (2017) (12)
- N-palmitoyl-D-glucosamine, A Natural Monosaccharide-Based Glycolipid, Inhibits TLR4 and Prevents LPS-Induced Inflammation and Neuropathic Pain in Mice (2021) (12)
- Human leukocytes differentially express endocannabinoid‐glycerol lipases and hydrolyze 2‐arachidonoyl‐glycerol and its metabolites from the 15‐lipoxygenase and cyclooxygenase pathways (2019) (12)
- Anandamide produced by Ca2+-insensitive enzymes induces excitation in primary sensory neurons (2014) (12)
- Arachidonic acid, protein kinase C activators and bud formation in Hydra vulgaris (1993) (12)
- Cannabinoids: a class of unique natural products with unique pharmacology (2021) (12)
- Experimental ischemia/reperfusion model impairs endocannabinoid signaling and Na+/K+ ATPase expression and activity in kidney proximal tubule cells (2018) (12)
- Chalcone Derivatives Activate and Desensitize the Transient Receptor Potential Ankyrin 1 Cation Channel, Subfamily A, Member 1 TRPA1 Ion Channel: Structure-Activity Relationships in vitro and Anti-Nociceptive and Anti-inflammatory Activity in vivo. (2016) (12)
- The effect of diterpenoidic diacylglycerols on tentacle regeneration in Hydra vulgaris. (1991) (12)
- Chronic blockade of CB1 receptors reverses startle gating deficits and associated neurochemical alterations in rats reared in isolation (2012) (12)
- Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activi (2016) (12)
- Design, Synthesis, Physicochemical and Pharmacological Profiling of 7-Hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide Derivatives with Anti-Osteoarthritic Activity in Vivo. (2020) (12)
- Harnessing the pyrroloquinoxaline scaffold for FAAH and MAGL interaction: definition of the structural determinants for enzyme inhibition (2016) (12)
- (Wh)olistic (E)ndocannabinoidome-Microbiome-Axis Modulation through (N)utrition (WHEN) to Curb Obesity and Related Disorders (2022) (11)
- Exploring the endocannabinoidome in genetically obese (ob/ob) and diabetic (db/db) mice: Links with inflammation and gut microbiota. (2021) (11)
- Targeting fatty acid amide hydrolase and transient receptor potential vanilloid‐1 simultaneously to modulate colonic motility and visceral sensation in the mouse: A pharmacological intervention with N‐arachidonoyl‐serotonin (AA‐5‐HT) (2017) (11)
- Fetal cannabinoid receptors and the “dis‐joint‐ed” brain (2014) (11)
- Structure-affinity relationships and pharmacological characterization of new alkyl-resorcinol cannabinoid receptor ligands: Identification of a dual cannabinoid receptor/TRPA1 channel agonist. (2014) (11)
- Effects of repeated long‐term psychosocial stress and acute cannabinoid exposure on mouse corticostriatal circuitries: Implications for neuropsychiatric disorders (2018) (11)
- Endocannabinoids: endogenous cannabinoid receptor ligands with neuromodulatory action, by V. Di Marzo, D. Melck, T. Bisogno and L. De Petrocellis, Vol. 21, pp. 521–528. (1999) (11)
- 2-Arachidonoyl-glycerol as an "endocannabinoid": limelight for a formerly neglected metabolite. (1998) (11)
- Exercise training and high-fat diet elicit endocannabinoid system modifications in the rat hypothalamus and hippocampus (2016) (11)
- &Dgr;9‐tetrahydrocannabivarin impairs epithelial calcium transport through inhibition of TRPV5 and TRPV6 (2018) (11)
- Tetrahydro-β-carboline derivatives targeting fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channels. (2013) (11)
- Cannabinoid receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database (2019) (10)
- Acute naloxone-precipitated morphine withdrawal elicits nausea-like somatic behaviors in rats in a manner suppressed by N-oleoylglycine (2019) (10)
- Rational drug design paradigms: the odyssey for designing better drugs. (2014) (10)
- Treatment With 2-Pentadecyl-2-Oxazoline Restores Mild Traumatic Brain Injury-Induced Sensorial and Neuropsychiatric Dysfunctions (2020) (10)
- Occurrence and biosynthesis of 11 (R)-hydroxy-eicosatetraenoic acid (11-R-HETE) in the Caribbean soft coralPlexaurella dichotoma (1996) (10)
- 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide: an effective scaffold for the design of either CB1 or CB2 receptor ligands. (2011) (10)
- In Silico Identification and Experimental Validation of (−)-Muqubilin A, a Marine Norterpene Peroxide, as PPARα/γ-RXRα Agonist and RARα Positive Allosteric Modulator (2019) (10)
- Cell signalling: Why fasting worms age slowly (2011) (10)
- Homologues and isomers of noladin ether, a putative novel endocannabinoid: interaction with rat cannabinoid CB(1) receptors. (2003) (10)
- Expression and Functions of the CB2 Receptor in Human Leukocytes (2022) (10)
- Desensitization of transient receptor potential vanilloid type-1 (TRPV1) channel as promising therapy of irritable bowel syndrome: characterization of the action of palvanil in the mouse gastrointestinal tract (2020) (10)
- Synthesis, cannabinoid receptor affinity, molecular modeling studies and in vivo pharmacological evaluation of new substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides. 2. Effect of the 3-carboxamide substituent on the affinity and selectivity profile. (2009) (10)
- Arylboronic acids as dual-action FAAH and TRPV1 ligands. (2016) (10)
- Anandamide-loaded nanoparticles: Preparation and characterization (2011) (9)
- Orexin-A and endocannabinoids are involved in obesity-associated alteration of hippocampal neurogenesis, plasticity, and episodic memory in mice (2021) (9)
- Lipids in neural function: modulation of behavior by oral administration of endocannabinoids found in foods. (2001) (9)
- Resorcinol-sn-glycerol derivatives: novel 2-arachidonoylglycerol mimetics endowed with high affinity and selectivity for cannabinoid type 1 receptor. (2011) (9)
- Placebo Effects in a Multiple Sclerosis Spasticity Enriched Clinical Trial with the Oromucosal Cannabinoid Spray (THC/CBD): Dimension and Possible Causes (2015) (9)
- 2-Arachidonoyl-glycerol as an "endocannabinoid": limelight for a formerly neglected metabolite. (1998) (9)
- Biology of endocannabinoids (2002) (9)
- Genetic Manipulation of sn-1-Diacylglycerol Lipase and CB1 Cannabinoid Receptor Gain-of-Function Uncover Neuronal 2-Linoleoyl Glycerol Signaling in Drosophila melanogaster. (2021) (9)
- New metabolically stable fatty acid amide ligands of cannabinoid receptors: Synthesis and receptor affinity studies. (2006) (9)
- The endocannabinoid system for the development of new drugs for spasticity (2007) (9)
- Role of the endocannabinoid system in the control of mouse myometrium contractility during the menstrual cycle (2017) (9)
- Arachidonic acid as an endogenous signal for the glutathione-induced feeding response in Hydra (1997) (9)
- Elongation of the Hydrophobic Chain as a Molecular Switch: Discovery of Capsaicin Derivatives and Endogenous Lipids as Potent Transient Receptor Potential Vanilloid Channel 2 Antagonists. (2018) (9)
- Enantioselective synthesis of 3(S)-hydroxy polygodial derivatives and evaluation of their vanilloid activity (2010) (9)
- β-Casomorphins: substitution of phenylalanine with β-homo phenylalanine increases the μ-type opioid receptor affinity (2000) (9)
- Structure-activity relationships of the ultrapotent vanilloid resiniferatoxin (RTX): The side chain benzylic methylene. (2010) (9)
- Biosynthesis of the Novel Endogenous 15-Lipoxygenase Metabolites N-13-Hydroxy-octodecadienoyl-ethanolamine and 13-Hydroxy-octodecadienoyl-glycerol by Human Neutrophils and Eosinophils (2021) (9)
- Cannabinoids in the Treatment of Neurological Disorders (2015) (8)
- Brain and peripheral anandamide amidohydrolase and its inhibition by synthetic arachidonate analogues. (1997) (8)
- Identification and Characterization of Cannabidiol as an OX1R Antagonist by Computational and In Vitro Functional Validation (2021) (8)
- Endocannabinoids in Energy Homeostasis and Metabolic Disorders (2008) (8)
- Hedonic eating in Prader–Willi syndrome is associated with blunted PYY secretion (2017) (8)
- Oleoyl glycine: interference with the aversive effects of acute naloxone-precipitated MWD, but not morphine reward, in male Sprague–Dawley rats (2019) (8)
- Coupling of cannabinoid receptors to intracellular calcium mobilization in rat insulinoma ß-cells (2007) (8)
- Endocannabinoid-dependent disinhibition of orexinergic neurons: Electrophysiological evidence in leptin-knockout obese mice (2017) (8)
- Development of a Rapid LC-MS/MS Method for the Quantification of Cannabidiol, Cannabidivarin, Δ9-Tetrahydrocannabivarin, and Cannabigerol in Mouse Peripheral Tissues. (2017) (8)
- Structure-Based Virtual Screening: Identification of Novel CB2 Receptor Ligands (2007) (8)
- Aquatic invertebrates open up new perspectives in eicosanoid research: biosynthesis and bioactivity. (1994) (8)
- Anandamide serves two masters in the brain. (2010) (8)
- Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 ( TRPA 1 ) and melastatin type-8 ( TRPM-8 ) (2008) (7)
- Novel diterpenoid diacylglycerols from marine molluscs: potent morphogens and protein kinase C activators (1996) (7)
- Orexin-A/Hypocretin-1 Controls the VTA-NAc Mesolimbic Pathway via Endocannabinoid-Mediated Disinhibition of Dopaminergic Neurons in Obese Mice (2021) (7)
- Design, Synthesis and In Vitro Experimental Validation of Novel TRPV4 Antagonists Inspired by Labdane Diterpenes (2020) (7)
- Endocannabinoids in the new millennium. (2002) (7)
- Neuropeptides and leukotriene release: Effect of peptide histidine isoleucine and secretin in platelet activating factor-stimulated rat lung (1987) (7)
- International Association for Cannabinoid Medicines (2013) (7)
- Hydra Tentacle Regeneration: A Model for the Study of the Involvement of Protein Kinase C and Phospholipase A2 in Cell Differentiation (1993) (7)
- 2-Pentadecyl-2-oxazoline ameliorates memory impairment and depression-like behaviour in neuropathic mice: possible role of adrenergic alpha2- and H3 histamine autoreceptors (2021) (7)
- Adverse effects of Δ9-tetrahydrocannabinol on neuronal bioenergetics during postnatal development (2020) (7)
- The endocannabinoidome as a substrate for noneuphoric phytocannabinoid action and gut microbiome dysfunction in neuropsychiatric disorders . (2020) (7)
- Enantioselective synthesis and vanilloid activity evaluation of 1-beta-(p-methoxycinnamoyl)polygodial, an antinociceptive compound from Drymis winteri barks. (2007) (7)
- Synthesis and Biological Evaluation of Phorbol‐Resiniferatoxin (RTX) Hybrids (2004) (7)
- Manipulation of the endocannabinoid system by a general anaesthetic. (2003) (7)
- Amygdalar CB2 cannabinoid receptor mediates fear extinction deficits promoted by orexin-A/hypocretin-1. (2021) (7)
- Metabolically labile cannabinoid esters: a 'soft drug' approach for the development of cannabinoid-based therapeutic drugs. (2007) (7)
- Endocannabinoids, food intake and body weight (2004) (7)
- Oleoyl alanine (HU595): a stable monomethylated oleoyl glycine interferes with acute naloxone precipitated morphine withdrawal in male rats (2020) (7)
- Iron overload causes osteoporosis in Thalassemia Major patients through interaction with TRPV 1 channels (2014) (7)
- Inhibitors of endocannabinoid breakdown for pain: not so FA(AH)cile, after all. (2012) (6)
- Lipopolysaccharide-induced pulmonary inflammation is not accompanied by a release of anandamide into the lavage fluid or a down-regulation of the activity of fatty acid amide hydrolase. (2004) (6)
- Sex-dependent effects of neonatal maternal deprivation on endocannabinoid levels in the adipose tissue: influence of diet (2016) (6)
- Synthesis and biological evaluation of new N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as cannabinoid receptor ligands. (2010) (6)
- Linking the Endocannabinoidome with Specific Metabolic Parameters in an Overweight and Insulin-Resistant Population: From Multivariate Exploratory Analysis to Univariate Analysis and Construction of Predictive Models (2021) (6)
- Synthesis of a potential photoactivatable anandamide analog. (2006) (6)
- Innenrücktitelbild: Development of an Activity-Based Probe and In Silico Design Reveal Highly Selective Inhibitors for Diacylglycerol Lipase-α in Brain (Angew. Chem. 46/2013) (2013) (6)
- Phospholipase A2 and protein kinase C enzymatic activities and their interactions in Hydra vulgaris (1995) (6)
- Synthesis and molecular targets of N-13-hydroxy-octadienoyl-ethanolamine, a novel endogenous bioactive 15-lipoxygenase-derived metabolite of N-linoleoyl-ethanolamine found in the skin and saliva. (2021) (6)
- Inhibitory effect of positively charged triazine antagonists of prokineticin receptors on the transient receptor vanilloid type-1 (TRPV1) channel. (2015) (6)
- Endocannabinoids Part II: pathological CNS conditions involving the endocannabinoid system and their possible treatment with endocannabinoid-based drugs (2001) (6)
- The possible involvement of protein kinase C and phospholipase A2 inHydra tentacle regeneration (2005) (6)
- Arachidonic acid and eicosanoids in Hydra: possible endogenous signals involved in chemoreception and modulation of the feeding behaviour. (1997) (6)
- Synthesis, conformational analysis and CB1 binding affinity of hairpin‐like anandamide pseudopeptide mimetics (2006) (6)
- Biosynthesis of hydroxyeicosatetraenoic acids (HETEs) in marine and freshwater hydroids (1993) (5)
- Corrigendum: New approaches and challenges to targeting the endocannabinoid system (2018) (5)
- Techniques for the Cellular and Subcellular Localization of Endocannabinoid Receptors and Enzymes in the Mammalian Brain. (2017) (5)
- Protective effects of N-oleoylglycine in a mouse model of mild traumatic brain injury. (2020) (5)
- Enantioselective synthesis of 1-(R)-hydroxypolygodial and its 9α epimer, 1-(R)-hydroxyisotadeonal (2007) (5)
- Alterations of the endocannabinoid system and circulating and peripheral tissue levels of endocannabinoids in sarcopenic rats (2021) (5)
- The Endocannabinoid System in Leptin-Driven Changes of Orexinergic Signaling Under Physiological and Pathological Conditions (2017) (5)
- Role of 2-Arachidonoyl-Glycerol and CB1 Receptors in Orexin-A-Mediated Prevention of Oxygen–Glucose Deprivation-Induced Neuronal Injury (2020) (5)
- N‐Acylethanolamine acid amidase (NAAA) is dysregulated in colorectal cancer patients and its inhibition reduces experimental cancer growth (2021) (5)
- Manipulation of the endocannabinoid system by a general anaesthetic (2003) (5)
- “De-liver-ance” From CB1: A Way to Counteract Insulin Resistance? (2012) (5)
- Altered Metabolism of Phospholipases, Diacylglycerols, Endocannabinoids, and N-Acylethanolamines in Patients with Mastocytosis (2019) (5)
- Why Can't We Be Friends? The Banning of Teacher-Student Communication Via Social Media and the Freedom of Speech (2012) (5)
- Three of a Kind: Control of the Expression of Liver-Expressed Antimicrobial Peptide 2 (LEAP2) by the Endocannabinoidome and the Gut Microbiome (2021) (5)
- The Synthesis of N‐Vanillyl‐arachidonoyl‐amide (Arvanil) and Its Analogues: An Improved Procedure for the Synthesis of the Key Synthon Methyl 14‐Hydroxy‐(all‐cis)‐5,8,11‐tetradecatrienoate. (2001) (4)
- Erratum to “The hypothalamic levels of the endocannabinoid, anandamide, peak immediately before the onset of puberty in female rats” [Life Sciences 70(12) (2002) 1407-1414] (2002) (4)
- Endocannabinoid system and its role in energy regulation (2006) (4)
- β-Endorphin in Neoroblastoma x Glioma hybrid cells (1985) (4)
- Cannabidiol improves vocal learning-dependent recovery from, and reduces magnitude of deficits following, damage to a cortical-like brain region in a songbird pre-clinical animal model (2019) (4)
- Mutual Links between the Endocannabinoidome and the Gut Microbiome, with Special Reference to Companion Animals: A Nutritional Viewpoint (2022) (4)
- Early Blockade of CB1 Receptors Ameliorates Schizophrenia-like Alterations in the Neurodevelopmental MAM Model of Schizophrenia (2022) (4)
- Spontaneous and Naloxone-Precipitated Withdrawal Behaviors From Chronic Opiates are Accompanied by Changes in N-Oleoylglycine and N-Oleoylalanine Levels in the Brain and Ameliorated by Treatment With These Mediators (2021) (4)
- PL03 Biochemistry and pharmacology of fatty acid amides – effects on inflammation, pain and pruritus and new perspectives in veterinary medicine (2006) (4)
- Impact of omega‐6 polyunsaturated fatty acid supplementation and γ‐aminobutyric acid on astrogliogenesis through the endocannabinoid system (2013) (4)
- "De-liver-ance" from CB(1): a way to counteract insulin resistance? (2012) (4)
- Correction to Design, Synthesis, and Physicochemical and Pharmacological Profiling of 7-Hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide Derivatives with Antiosteoarthritic Activity In Vivo. (2020) (4)
- Fifty years of ‘cannabinoid research’ and the need for a new nomenclature (2014) (4)
- Potential use of cannabimimetics in the treatment of cancer (2005) (4)
- Neuropeptides and leukotriene biosynthesis: The effect of calcitonin, peptide histidine valine-42, helodermin, neuropeptide Y and galanin (1988) (4)
- N-Oleoylglycine and N-Oleoylalanine Do Not Modify Tolerance to Nociception, Hyperthermia, and Suppression of Activity Produced by Morphine (2021) (3)
- FAAH-Catalyzed C-C Bond Cleavage of a New Multitarget Analgesic Drug. (2018) (3)
- Alteration of the endocannabinoid system in mouse brain during prion disease (2011) (3)
- Enzymological and molecular biological studies on anandamide amidohydrolase. (1999) (3)
- The Endocannabinoid System: Can It Contribute to Cannabis Therapeutics? (2008) (3)
- Effect of narrowband ultraviolet B treatment on endocannabinoid plasma levels in patients with psoriasis (2014) (3)
- PAF-mediated leukotriene biosynthesis in lungs : Control by the neuropeptidergic system (1987) (3)
- Cannabimovone, a Cannabinoid with a Rearranged Terpenoid Skeleton from Hemp (Eur. J. Org. Chem. 11/2010) (2010) (3)
- Biosynthesis and metabolism of endocannabinoids and their congeners from the monoacylglycerol andN-acyl-ethanolamine families. (2022) (3)
- Native opioid-like peptides in Squilla mantis ganglia (1985) (3)
- 714 Randomized Placebo-Controlled Multicenter Study on the Effect of Palmitoyl-Ethanolamide and Polydatin on Immune Activation in Patients With Irritable Bowel Syndrome (2014) (3)
- Cannabinoids and Chronic Liver Diseases (2022) (3)
- A novel prostaglandin metabolic pathway from a marine mollusc: prostaglandin-1,15-lactones. (1991) (3)
- PBOX-15 induces apoptosis and improves the efficacy of oxaliplatin in human colorectal cancer cell lines. (2013) (3)
- Signalling at vanilloid TRPV1 channels (2004) (3)
- Endocannabinoid pathways and their role in multiple sclerosis-related muscular dysfunction. (2011) (3)
- Oral Capsaicinoid Administration Alters the Plasma Endocannabinoidome and Fecal Microbiota of Reproductive-Aged Women Living with Overweight and Obesity (2021) (3)
- Regulation of Endocannabinoid Levels under Physiological and Pathological Conditions. A Mini‐review (2000) (3)
- Calcitonin gene-related peptide antagonises leukotriene D4-mediated contraction of the isolated guinea pig ileum (1986) (3)
- RIA/chromatographic evidence for novel opioid peptide(s) in Squilla mantis ganglia (1986) (3)
- Targeted Lipidomics Investigation of N ‐acylethanolamines in a Transgenic Mouse Model of AD: A Longitudinal Study (2019) (3)
- Dual role of neuropeptidergic system in pathology of asthma (1987) (3)
- Erratum to: Cannabinoids in the Treatment of Neurological Disorders (2015) (2)
- Increased skin levels of the Aliamide Palmitoylethanolamide and other endogenous fatty acid amides in dogs with atopic dermatitis (2008) (2)
- New Potential Therapies from Vanilloid Transient Receptor Cation (TRPV) Channels. (2008) (2)
- β‐Casomorphins: Substitution of Phenylalanine with β‐homo Phenylalanine Increases the μ‐Type Opioid Receptor Affinity. (2000) (2)
- Neuromodulatory actions neuromodulatory actions of endocannabinoids in pain and sedation. (2003) (2)
- 5 Anandamide and Other Acylethanolamides (2009) (2)
- The role of consciousness in biological cybernetics: emergent adaptive and maladaptive behaviours in artificial agents governed by the projective consciousness model (2020) (2)
- Mechanisms underlying in vivo neuroprotection by the endocannabinoid anandamide and the cannabinoid/vanilloid receptor agonist, arvanil (2003) (2)
- A Glucuronic Acid-Palmitoylethanolamide Conjugate (GLUPEA) Is an Innovative Drug Delivery System and a Potential Bioregulator (2021) (2)
- N-Acyldopamines and N-Acylserotonins: From Synthetic Pharmacological Tools to Endogenous Multitarget Mediators (2015) (2)
- Play an ADAGIO with a STRADIVARIUS: the right patient for CB1 receptor antagonists? (2008) (2)
- ORIGINAL ARTICLE The cannabinoid D 9 -tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesity (2013) (2)
- Assessment of the Effects of Dietary Vitamin D Levels on Olanzapine-Induced Metabolic Side Effects: Focus on the Endocannabinoidome-Gut Microbiome Axis (2021) (2)
- The ever-expanding world of the endocannabinoids: A concise introduction (2015) (2)
- Human and Mouse Eosinophils Differ in Their Ability to Biosynthesize Eicosanoids, Docosanoids, the Endocannabinoid 2-Arachidonoyl-glycerol and Its Congeners (2022) (2)
- Intuitive eating is associated with elevated levels of circulating omega-3-polyunsaturated fatty acid-derived endocannabinoidome mediators (2020) (2)
- Deletion of the gene encoding prostamide/prostaglandin F synthase reveals an important role in regulating intraocular pressure. (2021) (2)
- Hemp seed significantly modulates the endocannabinoidome and produces beneficial metabolic effects with improved intestinal barrier function and decreased inflammation in mice under a high-fat, high-sucrose diet as compared with linseed (2022) (2)
- Alterations in the Endocannabinoid System as a Link Between Unbalanced Energy Homeostasis, Neuroinflammation, and Neurological and Neuropsychiatric Disorders (2013) (2)
- The endocannabinoid system in metabolic control: a preface. (2009) (2)
- Cannabimimetic eicosanoids in cancer and inflammation: an update. (2002) (2)
- The Palmitoylethanolamide and Oleamide Enigmas: Are These Two Fatty Acid Amides Cannabimimetic? (1999) (2)
- Hydra vulgaris ω10-lipoxygenase is used in vivo to synthesize new α-linolenic acid metabolites (2005) (2)
- THE ENDOGENOUS CANNABINOID SIGNALING SYSTEM: CHEMISTRY AND PHYSIOLOGY (1997) (2)
- Endocannabinoid-Based Molecules as Potential Therapeutic Drugs (2005) (2)
- Maternal omega-3 intake differentially affects the endocannabinoid system in the progeny`s neocortex and hippocampus: impact on synaptic markers: n-3 maternal diet sway progeny`s synaptic markers. (2021) (2)
- Novel mechanisms in obesity, type 2 diabetes and accompanying inflammation: focus on lipid signaling (2010) (1)
- Inside Back Cover: Development of an Activity-Based Probe and In Silico Design Reveal Highly Selective Inhibitors for Diacylglycerol Lipase-α in Brain (Angew. Chem. Int. Ed. 46/2013) (2013) (1)
- Corrigendum to "Systemic administration of serotonin exacerbates abdominal pain and colitis via interaction with the endocannabinoid system" [Biochem. Pharmacol. 161 (2019) 37-51]. (2019) (1)
- Neuroendocrine Responses to Hedonic Eating in Obese Patients with and Without Binge Eating (2015) (1)
- REVIEW Role and regulation of acylethanolamides in energy balance: focus on adipocytes and b -cells (2007) (1)
- Endocannabinoid pathways and their role in multiple sclerosis-related muscular dysfunction (2011) (1)
- CB1, but not CB2, mediates stimulation of bone formation induced by traumatic brain injury. (2006) (1)
- Anandamides and Diet: A New Pot of Nutritional Research is Simmering (2004) (1)
- Su1124 SMALL INTESTINE EPITHELIAL ORGANOIDS AS A MODEL TO INVESTIGATE THE ROLE OF THE ENDOCANNABINOIDOME ON INTESTINAL PARACELLULAR PERMEABILITY DURING INFLAMMATION (2020) (1)
- The endocannabinoid system in metabolic control: a preface. (2009) (1)
- Positive association between plasmatic levels of orexin A and the endocannabinoid-derived 2-arachidonoyl lysophosphatidic acid in Alzheimer’s disease (2022) (1)
- 739 CIRCULATING AND HEPATIC ENDOCANNABINOIDS AND ENDOCANNABINOID-RELATED MOLECULES IN PATIENTS WITH LIVER CIRRHOSIS (2009) (1)
- Abdominal Obesity and the Endocannabinoid System: From Basic Aspects to Clinical Management of Related Cardiometabolic Risk (2008) (1)
- Preparation and characterization of D 9-tetrahydrocannabinol-loaded biodegradable polymeric microparticles and their antitumoral efficacy on cancer cell lines (2016) (1)
- G02 Identification of functional TRPV1 vanilloid receptor in MCF-7 cells (2006) (1)
- Synthetic bioactive olivetol-related amides: The influence of the phenolic group in cannabinoid receptor activity. (2020) (1)
- α2-Adrenoceptor agonist induces peripheral antinociception via the endocannabinoid system (2020) (1)
- Beta-casomorphins: substitution of phenylalanine with beta-homo phenylalanine increases the mu-type opioid receptor affinity. (2000) (1)
- Established and Emerging Concepts of Cannabinoid Action on Food Intake and their Potential Application to the Treatment of Anorexia and Cachexia (2014) (1)
- STUDIES ON THE IN VITRO PHARMACOLOGY AND METABOLISM OF PROSTAGLANDIN–ETHANOLAMIDES (PROSTAMIDES) IN THE FELINE IRIS (2004) (1)
- Corrigendum to Halogenation of a capsaicin analogue leads to novel vanilloid TRPVI receptor antagonists (2003) (1)
- Phytocannabinoids: a growing family of plant natural products with increasing pharmacological and clinical importance (2016) (1)
- Cannabinoids: Di Marzo/Cannabinoids (2014) (1)
- P.1.g.064 Possible dysregulation of the endocannabinoid system in a cohort of patients with Dravet syndrome (2016) (1)
- Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men (2013) (1)
- Effect of Docosahexaenoic Acid (DHA) at the Enteric Level in a Synucleinopathy Mouse Model (2021) (1)
- Endocannabinoid Overactivity and Abdominal Obesity (2008) (1)
- Temperature-Sensitive Transient Receptor Potential Channels as Ionotropic Cannabinoid Receptors (2013) (1)
- ω10-Lipoxygenase products of α-linolenic acid are esterified to phospholipids inHydra vulgaris (1996) (1)
- Cannabidiol alters mitochondrial bioenergetics via VDAC1 and triggers cell death in hormone-refractory prostate cancer. (2023) (1)
- TRPV1 in Neuropathic Pain and Neurological and Neuropsychiatric Disorders (2010) (1)
- Naphthalene and 2,3-dihydrobenzo[b][1,4]dioxine derivatives with extended side chains as new scaffolds of CB2-selective ligands (2014) (1)
- Synthesis and binding study of certain 6-arylalkanamides as molecular probes for cannabinoid receptor subtypes (2013) (1)
- Correction to: 2-Pentadecyl-2-oxazoline ameliorates memory impairment and depression-like behaviour in neuropathic mice: possible role of adrenergic alpha2- and H3 histamine autoreceptors (2021) (1)
- Function of endocannabinoids and related compounds in sleep (2008) (1)
- Cannabinoid Properties of Methylfluorophosphonate Analogs 1 (2000) (1)
- Studies on the Interactions of Prostamides With Fatty Acid Amide Hydrolase, the Anandamide Transporter, and VR1 Receptors (2002) (1)
- Different targets of anti-glucocorticoid treatment have been proposed, acting at supra-hypothalamic, HPA axis, glucocorticoid receptor and post-receptor levels. (2013) (1)
- Study of the expression profile and pharmacological role of the CB 1 receptor in Duchenne Muscular Dystrophy ( DMD ) muscles : a new opportunity to reinforce muscle repair and locomotor activity (2015) (0)
- 30 P The endocannabinoid system and colorectal carcinoma a possible role in the inhibition of cancer growth (2002) (0)
- CB1 cannabinoid receptors mediate cognitive deficits and structural plasticity changes associated with nicotine withdrawal (2017) (0)
- Involvement of the endocannabinoid system in a neurodevelopmental model of schizophrenia (2015) (0)
- DESIGN, SYNTHESIS, AND EVALUATION OF (ISO)NIPECOTAMIDE ANDPIPERAZINYLUREA DERIVATIVES AS TRPV1 MODULATORS (2013) (0)
- Dual control by cannabinoid CB1 and CB2 receptors of S100B protein expression and glial cell proliferation following administration of beta amyloid in vitro and in vivo. (2006) (0)
- Have you seen ? Fetal cannabinoid receptors and the “ disjointed ” brain (2014) (0)
- NAPE-PLD, 12-LOX and TRPV1 immunoexpression in the hippocampus and cerebellum of the mouse brain (2007) (0)
- Phytocannabinoids in cancer treatment (2011) (0)
- Participants with Normal Weight or with Obesity Show Different Relationships of 6-n-Propylthiouracil (PROP) Taster Status with BMI and Plasma Endocannabinoids (2017) (0)
- The time course of erythrocyte membrane fatty acid concentrations during and after treatment of non-human primates with increasing doses of an omega-3 rich phospholipid preparation derived from krill-oil (2017) (0)
- Short and efficient synthesis of alkylresorcinols: a route for the preparation of cannabinoids (2022) (0)
- 250 ANANDAMIDE CAUSES ANALGESIA IN NEUROPATHIC RATS BY ACTIVATING SPINAL TRPV1 RECEPTORS (2009) (0)
- Synthesis and antitumor evaluation of 1,8-naphthyridine-2-(1H)-on-3carboxamide derivatives as CB2 selective agonists (2008) (0)
- 37 ANTINOCICEPTIVE TR(i)PS FROM SUPRASPINAL ENDOVANILLOID SIGNALLING TO PLANT CANNABINOIDS (2009) (0)
- Differential effects of EPA and DHA on plasma and adipose tissue lipid mediators: the ComparED study (2020) (0)
- Author Correction: CB1 receptor activation induces intracellular Ca2+ mobilization and 2-arachidonoylglycerol release in rodent spinal cord astrocytes (2018) (0)
- Comprar Abdominal Obesity and the Endocannabinoid System: From Basic Aspects to Clinical Management of Related Cardiometabolic Risk | Jean-Pierre Despres | 9781420060843 | Informa Healthcare (2008) (0)
- Regulation on spinal nociceptive TRPV1/CB1 processing as therapeutic opportunities in a rat model of neuropathic pain (2011) (0)
- Enantioselective Synthesis and Vanilloid Activity Evaluation of 3-B-Hydroxypolygodial and its Analogues (2009) (0)
- Cannabichromene (CBC), cannabidivarin (CBDV) and/or cannabidivarin acid (CBDVA) for the treatment of neurodegenerative diseases (2012) (0)
- Abdominal obesity and the endocannabinoid system (2014) (0)
- Effects of chronic exercise on the endocannabinoid system in Wistar rats with high-fat diet-induced obesity (2016) (0)
- Phytocannabinoids: a growing family of plant natural products with increasing pharmacological and clinical importance (2016) (0)
- Exogenous and endogenous : Cannabimimetic metabolites (1998) (0)
- Luciano De Petrocellis-CNS&ND-MS (2016) (0)
- Olivetol- and Resorcinol-Anandamide “hybrids”: design, synthesis, binding and molecular modeling of potent cannabinoid receptor ligands (2007) (0)
- S.11.03 Cannabinoid receptor antagonists and inhibitors of endocannabinoid metabolism as potential therapeutic drugs (2004) (0)
- 196 The endocannabinoid tone regulates human sebocyte biology (2016) (0)
- A1 ADENOSINE RECEPTOR REGULATES ATP-MEDIATED MICROGLIAL ACTIVATION IN VIVO AND IN VITRO: ROLE IN THE SPINAL NEURONAL PLASTICITY IN NEUROPATHIC MICE (2013) (0)
- Synthesis, release and action of leukotrienes in the isolated rat heart (1988) (0)
- Distribution and Activity of Fatty Acid Amide Hydralase (FAAH) in the Gastrointestinal Neurons of Mouse (2005) (0)
- Palmitoylethanolamide counteracts substance P-induced mast cell activation in vitro by stimulating diacylglycerol lipase activity (2019) (0)
- Skin mast cells and endogenous fatty acid amides in canine atopic dermatitis: a pilot study. (2008) (0)
- 184 Regulation of the Enteric Neuromotor and Sensory Functions in the Mouse With N-Arachidonoyl-Serotonin (AA-5-HT), a Dual Fatty Acid Amide Hydrolase (FAAH) Inhibitor and TRPV1 Antagonist (2016) (0)
- Cannabimovone, a Cannabinoid with a Rearranged Terpenoid Skeleton from Hemp. (2010) (0)
- Early modulation of the endocannabinoid tone prevents the onset of a schizophrenia-likephenotype (2017) (0)
- EPA-0534 - Endocannabinoid and Gastroenteric Hormone Responses to Hedonic Eating in Humans: Implications for Eating Disorders (2014) (0)
- Mo-S4:3 CB1 blockade, a new therapeutic target for the treatment of cardiometabolic disorders: Mechanism(s) of action (2006) (0)
- 2-AG promotes the expression of conditioned fear via cannabinoid receptor type 1 on GABAergic neurons (2015) (0)
- The Endocannabinoid System and its Modulation by Phytocannabinoids (2015) (0)
- The endocannabinoidome in human placenta: Possible contribution to the pathogenesis of preeclampsia. (2023) (0)
- CB1 receptor activation induces intracellular Ca2+ mobilization and 2-arachidonoylglycerol release in rodent spinal cord astrocytes (2018) (0)
- Differences In Serum Levels Of Lysophosphatidic Acid And Orexin/Hypocretin In Normal Weight And Obese Patients,Along The Continuum From Health People To Alzheimer’s Disease (2018) (0)
- (Wh)olistic (E)ndocannabinoidome-Microbiome-Axis Modulation through (N)utrition (WHEN) to Curb Obesity and Related Disorders (2022) (0)
- Facile and Sustainable Synthesis of Commendamide and its Analogues (2022) (0)
- Desensitization of transient receptor potential vanilloid type-1 (TRPV1) channel as promising therapy of irritable bowel syndrome: characterization of the action of palvanil in the mouse gastrointestinal tract (2020) (0)
- Targeted lipidomics: endocannabinoids and other endolipid modulators (2005) (0)
- Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer (2012) (0)
- Plasma OEA level is correlated with muscle mass and mobility in old rats (2020) (0)
- Acute naloxone-precipitated morphine withdrawal elicits nausea-like somatic behaviors in rats in a manner suppressed by N-oleoylglycine (2019) (0)
- 2-Pentadecyl-2-oxazoline ameliorates memory impairment and depression-like behaviour in neuropathic mice: possible role of adrenergic alpha2- and H3 histamine autoreceptors (2021) (0)
- EPA-1474 – Psychosocial Stress and Psychiatric Phenotypes: Endocannabinoids and Cannabinoid Receptor (CBR) Expression in Cortico-Striatal Connectivity (2014) (0)
- The EC System and Central Control of Energy Balance—The Hypothalamus (2008) (0)
- Anandamide produced by Ca2+-insensitive enzymes induces excitation in primary sensory neurons (2013) (0)
- Potential drug metabolites as endocannabinoids and endovanilloids (2007) (0)
- Functional Plasticity of Lipid Mediators: The Example of Endocannabinoids (2005) (0)
- Effects of diisononyl phthalate (DiNP) on the endocannabinoid and reproductive systems of male gilthead sea bream (Sparus aurata) during the spawning season (2019) (0)
- Design, synthesis, and biological evaluation of new heterocyclic azotate derivatives as CB2 selective agonists (2007) (0)
- Activation of cannabinoid type 1 receptor (CB1) modulates oligodendroglial process branching complexity in rat hippocampal cultures stimulated by olfactory ensheathing glia-conditioned medium (2023) (0)
- Human eosinophils and neutrophils biosynthesize novel 15-lipoxygenase metabolites from 1-linoleoyl-glycerol and N-linoleoyl-ethanolamine (2020) (0)
- endoCANNABINOIDS (2013) (0)
- First Evidence of the Protective Effects of 2-Pentadecyl-2-Oxazoline (PEA-OXA) in In Vitro Models of Acute Lung Injury (2022) (0)
- Neuropeptides and leukotriene biosynthesis (1988) (0)
- Exercise training and high-fat diet elicit endocannabinoid system modifications in the rat hypothalamus and hippocampus (2016) (0)
- Synthesis of potential theanine metabolites, related structures and their affinity for CB receptors (2007) (0)
- This first 2014 issue of Recent Patents in CNS Drug Discovery covers a range of rather diverse, but not necessarily unrelated topics. Introduction. (2014) (0)
- Questions & Answers (2011) (0)
- 344 SPINAL VANILLOID TRPV1 RECEPTOR AS A TARGET FOR ENDOGENOUS ANANDAMIDE IN NEUROPATHIC PAIN (2010) (0)
- Pathogenesis of the metabolic syndrome and the influence of cannabinoids (2008) (0)
- Cannabinoids in the Treatment of Neurological Disorders (2015) (0)
- The effect of hyperinsulinaemic-euglycaemic clamp on circulating endocannabinoids in insulin sensitive vs. insulin-resistant obese post-menopausal women (2011) (0)
- The endocannabinoidome mediator N-oleoylglycine is a novel protective agent against 1-methyl-4-phenyl-pyridinium-induced neurotoxicity (2022) (0)
- Use of cannabinoids comprising cannabichromene, cannabidivarin and cannabidivarin acid, for preventing or treating neurodegenerative diseases or disorders e.g. Alzheimer's disease, Parkinson's disease, cardiac ischemia and stroke (2013) (0)
- Rational design, synthesis, biological evaluation and labelling of selective cannabinoid CB2 receptor agonists as anticancer agents (2011) (0)
- Krill Oil supplementation modifies endocannabinoid congeners profile in cachectic advanced cancer patients (2014) (0)
- Phytocannabinoids in ther treatment of cancer (2010) (0)
- Endocannabinoid and Gastroenteric Hormone Responses to Hedonic Eating in Healthy Humans: Implications for Eating Disorders (2014) (0)
- Decrease of anandamide ratio between visceral and subcutaneous adipose tissues by dietary EPA and DHA phosphatidylcholine improves metabolic syndrome in obese zucker rats (2012) (0)
- Track 2: From genes and environment to pathophysiology (2014) (0)
- New biphenylic derivatives as CB2 receptor selective ligands (2013) (0)
- "Soft Drugs" Based on Cannabinoid Receptor Ligands as Potential Local Analgesic and Antiglaucoma Agents (2007) (0)
- UMBELLULONE, THE OFFENSIVE PRINCIPLE OF THE HEADACHE TREE (UMBELLULARIA CALIFORNICA), STIMULATES THE TRIGEMINOVASCULAR SYSTEM VIA TRPA1 ACTIVATION (2011) (0)
- P.3.c.010 Early pharmacological modulation of the endogenous cannabinoid signaling counteracts the phenotype in a rodent developmental disruption model of schizophrenia at adulthood (2016) (0)
- Article: EPA-0534 Topic: E06-e-Poster Oral Session 06: Child Psychiatry and Personality Disorders ENDOCANNABINOID AND GASTROENTERIC HORMONE RESPONSES TO HEDONIC EATING IN HUMANS: IMPLICATIONS FOR EATING DISORDERS (2014) (0)
- 3-Hydroxy-oxylipins and derivatives, novel fungal lipid mediators produced by host–pathogen interaction, activate capsaicin receptor (TRPV1): A mechanism for pain in vulvovaginal candidiasis (2007) (0)
- ' s report Title : Synergistic action of N-palmitoylethanolamine and the FAAH inhibitor URB 597 on melanoma growth Version : 1 Date : 11 November 2011 (0)
- CB1 and CB2-independent neuroprotective effects of oxyhomologs of palmitoyl ethanolamine on an in vitro model of oxidative stress (2005) (0)
- A Gradient of 2-Arachidonoylglycerol Regulates Mouse Epididymal Sperm Cell Start-Up Short title: 2-AG regulates sperm motility (2009) (0)
- Genetic and pharmacological regulation of the endocannabinoid CB1 receptor in Duchenne muscular dystrophy (2018) (0)
- Changes in the endocannabinoid signaling system in CNS structures of TDP-43 transgenic mice: relevance for a neuroprotective therapy in TDP-43-related disorders (2015) (0)
- Peripubertal cannabidiol treatment prevents molecular and behavioral changes in neurodevelopmental model of schizophrenia (2018) (0)
- Retinal projections to the lateral hypothalamus are involved in the light-mediated endocannabinoid synthesis: Orexin and 2-acylglicerol interaction in the light-entrainable rhythms. (2011) (0)
- Rapid Participation of Prostaglandin E, in Dopamine D2 Receptor-Dependent Potentiation of Arachidonic Acid Release (2006) (0)
- Abstracts of the 6th Meeting of the Neapolitan Brain Group (2018) (0)
- P.1.c.007 Prenatal influences facilitate the precipitation of a schizophrenia-like phenotype: assessing the role of the endocannabinoid system (2015) (0)
- Cover Picture: Synthesis and Biological Evaluation of Phorbol-Resiniferatoxin (RTX) Hybrids (Eur. J. Org. Chem. 16/2004) (2004) (0)
- Abdominal Obesity As a Therapeutic Target to Manage the Atherogenic Dyslipidemia and Related Metabolic Abnormalities (2008) (0)
- 202 TRPV1 AND MU OPIOID RECEPTOR COMBINED ACTIVATION INDUCES ANALGESIA VIA BRAINSTEM DESCENDING ANTINOCICEPTIVE PATHWAYS (2009) (0)
- Abdominal Obesity, Metabolic Syndrome and Risk of Cardiovascular Disease (2008) (0)
- Orexin induces the production of an endocannabinoid-derived lysophosphatidic acid eliciting hypothalamic synaptic loss in obesity. (2023) (0)
- ResearchAnandamide and Palmitoylethanolamide involvement in human stroke (2010) (0)
- Enantioselective Synthesis and Vanilloid Activity Evaluation of 1-β-(p-Methoxycinnamoyl)polygodial (I), an Antinociceptive Compound from Drymis winteri Barks. (2008) (0)
- A Designer Diet Induces Thermogenic Adipocytes via Raptor and Prolongs Healthy Lifespan (2019) (0)
- Endocannabinoid signalling: a common target for high fat diets and substances of abuse? (2005) (0)
- Phytocannabinoidome and the Endocannabinoidome: How Close Are They? (2018) (0)
- Opioid-cannabinoid interactions: A general introduction to the endocannabinoid system and its interactions with opioid receptor signalling (2011) (0)
- Endocannabinoid system and schizophrenia: behavioral andmolecular changes in neurodevelopmental animal model (2016) (0)
- Endocannabinoids and endocannabinoid-related molecules in patients with liver cirrhosis (2009) (0)
- Research Article Differential diurnal variations of anandamide and 2-arachidonoyl-glycerol levels in rat brain (2004) (0)
- Nitric Oxide Endothelial Cells and Its Regulation by Anandamide Uptake by Human TRANSDUCTION: MECHANISMS OF SIGNAL (2019) (0)
- Validation of a fast and sensitive UPLC-MS/MS quantitative method for N-acyl taurine analysis in biological samples (2023) (0)
- Sex-dependent effects of neonatal maternal deprivation on endocannabinoid levels in the adipose tissue: influence of diet (2016) (0)
- Design, synthesis, and biological evaluation of 1,8-naphthyridin-2(1H)-on-3-carboxamide, quinolin-2(1H)-on-3-carboxamide and 2-oxo-1,2-dihydropyridine-3-carboxamide derivatives as CB2 selective ligands (2008) (0)
- Studies on Endocannabinoid Levels in Normal and Glaucomatous Eyes (2005) (0)
- Impact of dietary fat on the endocannabinoid system (2011) (0)
- Critical role of the endocannabinoid system in bone homeostasis (2007) (0)
- Erratum to: Cannabinoids in the Treatment of Neurological Disorders (2015) (0)
- Cannabinoid–vanilloid receptor interactions in pain signaling (2003) (0)
- Abstract: 69 IS HEPATIC STEATOTIS THE CULPRIT OF DYSLIPIDEMIA IN SUBJECTS WITH ABDOMINAL OBESITY? (2009) (0)
- Oleoyl glycine: interference with the aversive effects of acute naloxone-precipitated MWD, but not morphine reward, in male Sprague–Dawley rats (2019) (0)
- P.1.d.012 Role of the endocannabinoid system and vanilloid TRPV1 channels in the phenotype of dopamine D3 receptor knock-out mice (2009) (0)
- New Substituted 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as High Affinity hCB1 Ligands (2009) (0)
- Kahweol, a natural diterpene from coffee, induces peripheral antinociception by endocannabinoid system activation (2021) (0)
- Preclinical investigation in FAAH inhibition as a neuroprotective therapy for frontotemporal dementia using TDP-43 transgenic male mice (2023) (0)
- Erratum to: Responses of peripheral endocannabinoids and endocannabinoid‑related compounds to hedonic eating in obesity (2016) (0)
- S9 CANNABINOID RECEPTORS AND THEIR ROLE IN NEUROPROTECTION (2006) (0)
- Fatty acid derivatives of phenethylamine and glycerol as endocannabinoids and endovanilloids (2012) (0)
- Cell signalling: why fasting worms age slowly. (2011) (0)
- Different targets of anti-glucocorticoid treatment have been proposed, acting at supra-hypothalamic, HPA axis, glucocorticoid receptor and post-receptor levels. (2013) (0)
- Gene deletion studies reveal a critical role for prostamide/prostaglandin F2α synthase in prostamide F2α formation (2020) (0)
- Compositions and methods for modulating specific for N-acylethanolamines amidases to be used in the therapy of inflammatory diseases (2012) (0)
- Title Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain Permalink (2016) (0)
- Meet Our Editor (2015) (0)
- Stimulation of CB2 directly stimulates cell survival pathways. (2013) (0)
- P4.033 The amnesic effects induced by β-amyloidfragment 1–42 involve cannabinoid neurotransmission in the brain (2004) (0)
- Regulation of intracellular calcium in insulinoma cells by bombesin and cannabinoids: same coupling for different informations? (2007) (0)
- A Lipidomics- and Transcriptomics-Based Analysis of the Intestine of Genetically Obese (ob/ob) and Diabetic (db/db) Mice: Links with Inflammation and Gut Microbiota (2023) (0)
- Cannabimimetic eicosanoids: An overview of their metabolic pathways and potential role in cancer and inflammation (1999) (0)
- Endocannabinoids in the new millennium. (2002) (0)
- Synthesis and biological evaluation of pyridine derivatives as cannabinoid receptor ligands (2009) (0)
- Tu1205 OBESITY-RELATED ENDOGENOUS MICROENVIRONMENT IMPACTS INSULIN SIGNALING AND INTESTINAL FUNCTIONS OF INTESTINAL ORGANOIDS (2020) (0)
- P.705 Neonatal CB1 receptor blockade differentially affects behavioural responses in normal and prenatally MAM exposed rats (2019) (0)
- Special Issue: The endocannabinoid system in metabolic control. (2009) (0)
- The Effects of Peripubertal THC Exposure in Neurodevelopmental Rat Models of Psychopathology (2023) (0)
- Human and murine eosinophils differ in their ability to synthesize key bioactive lipids involved in asthma (2020) (0)
- The cannabinoid receptor type 2 is down-regulated in downstream portions of human carotid plaques (2012) (0)
- The effects of CB1-receptor blockade on mean arterial pressure (A) and cerebrocortical blood flow (B). (2013) (0)
- High-Voltage-Activated Calcium Currents in Cannabinoids Modulate the P-Type (2015) (0)
- Synthesis and biological evaluation of 1,8-naphthyridine and quinoline derivatives as CB2 selective agonists (2007) (0)
- Use of cannabinoids comprising cannabichromene, cannabidivarin and cannabidivarin acid, for preventing or treating neurodegenerative diseases or disorders e.g. Alzheimer's disease, Parkinson's disease, cardiac ischemia and stroke (2013) (0)
- Author Correction: CB1 receptor activation induces intracellular Ca2+ mobilization and 2-arachidonoylglycerol release in rodent spinal cord astrocytes (2018) (0)
- TRPV1 modulators: Synthesis and in vitro evaluation of 1-heteroaryl piperidinecarboxamide and piperazinylurea derivatives. (2015) (0)
- Pain control between cannabinoid and vanilloid receptors: cooperations and counteractions (2011) (0)
- P17.2 Relationship among the endocannabinoid system, atherosclerosis and cognitive status (2011) (0)
This paper list is powered by the following services:
What Schools Are Affiliated With Vincenzo Di Marzo?
Vincenzo Di Marzo is affiliated with the following schools: