Virginia Man-Yee Lee | Academic Influence

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Virginia Man-Yee Lee

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Biology
Philosophy

Virginia Man-Yee Lee's Degrees

PhD Neuroscience University of Pennsylvania
Doctorate Medicine University of Pennsylvania

Why Is Virginia Man-Yee Lee Influential?

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According to Wikipedia, Virginia Man-Yee Lee is a Chinese-born American biochemist and neuroscientist who specializes in the research of Alzheimer's disease. She is the current John H. Ware 3rd Endowed Professor in Alzheimer's Research at the Department of Pathology and Laboratory Medicine, and the director of the Center for Neurodegenerative Disease Research and co-director of the Marian S. Ware Alzheimer Drug Discovery Program at the Perelman School of Medicine, University of Pennsylvania. She received the 2020 Breakthrough Prize in Life Sciences.

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Virginia Man-Yee Lee's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice (2012) (1886)
A68: a major subunit of paired helical filaments and derivatized forms of normal Tau. (1991) (1399)
Initiation and Synergistic Fibrillization of Tau and Alpha-Synuclein (2003) (802)
Exogenous α-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells (2009) (793)
Activation of the Wnt signaling pathway: a molecular mechanism for lithium action. (1997) (650)
Solid-State NMR Structure of a Pathogenic Fibril of Full-Length Human α-Synuclein (2016) (640)
Seeding of Normal Tau by Pathological Tau Conformers Drives Pathogenesis of Alzheimer-like Tangles* (2011) (556)
Dityrosine cross-linking promotes formation of stable alpha -synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies. (2000) (529)
Role for Akt3/Protein Kinase Bγ in Attainment of Normal Brain Size (2005) (493)
Insulin and Insulin-like Growth Factor-1 Regulate Tau Phosphorylation in Cultured Human Neurons* (1997) (491)
Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite–like aggregates (2014) (431)
Increased F2‐isoprostanes in Alzheimer's disease: evidence for enhanced lipid peroxidation in vivo (1998) (414)
Microtubule-binding drugs offset tau sequestration by stabilizing microtubules and reversing fast axonal transport deficits in a tauopathy model. (2005) (379)
Maturation and Endosomal Targeting of β-Site Amyloid Precursor Protein-cleaving Enzyme (2000) (370)
Identification of the major multiphosphorylation site in mammalian neurofilaments. (1988) (368)
Cellular Milieu Imparts Distinct Pathological α-Synuclein Strains in α-Synucleinopathies (2018) (361)
Role for Akt3/protein kinase Bgamma in attainment of normal brain size. (2005) (351)
Phosphorylated α-Synuclein Is Ubiquitinated in α-Synucleinopathy Lesions* (2002) (347)
Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice. (2011) (345)
Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies* (2009) (322)
Protein Kinase C-dependent α-Secretase Competes with β-Secretase for Cleavage of Amyloid-β Precursor Protein in the Trans-Golgi Network* (2000) (321)
The structure, biochemical properties, and immunogenicity of neurofilament peripheral regions are determined by phosphorylation state. (1985) (307)
Role of α-Synuclein Carboxy-Terminus on Fibril Formation in Vitro† (2003) (296)
Widespread transneuronal propagation of α-synucleinopathy triggered in olfactory bulb mimics prodromal Parkinson’s disease (2016) (287)
High Tolerance and Delayed Elastic Response of Cultured Axons to Dynamic Stretch Injury (1999) (287)
α-Synuclein Immunotherapy Blocks Uptake and Templated Propagation of Misfolded α-Synuclein and Neurodegeneration (2014) (272)
Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB (2014) (269)
The human mid‐size neurofilament subunit: a repeated protein sequence and the relationship of its gene to the intermediate filament gene family. (1987) (267)
The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases. (2002) (265)
Reversible Inhibition of α-Synuclein Fibrillization by Dopaminochrome-mediated Conformational Alterations* (2005) (261)
Lewy Body-like α-Synuclein Aggregates Resist Degradation and Impair Macroautophagy*♦ (2013) (254)
Functional consequences of alpha-synuclein tyrosine nitration: diminished binding to lipid vesicles and increased fibril formation. (2004) (244)
Chaperone‐like activity of synucleins (2000) (236)
Human neurons derived from a teratocarcinoma cell line express solely the 695-amino acid amyloid precursor protein and produce intracellular beta-amyloid or A4 peptides. (1993) (231)
Differentiation of NTERA-2 clonal human embryonal carcinoma cells into neurons involves the induction of all three neurofilament proteins (1986) (228)
Protein transmission in neurodegenerative disease (2020) (226)
Maturation and endosomal targeting of beta-site amyloid precursor protein-cleaving enzyme. The Alzheimer's disease beta-secretase. (2000) (221)
Expression and analysis of presenilin 1 in a human neuronal system: localization in cell bodies and dendrites. (1996) (216)
A Precipitating Role for Truncated α-Synuclein and the Proteasome in α-Synuclein Aggregation (2005) (211)
Muscarinic Regulation of Alzheimer's Disease Amyloid Precursor Protein Secretion and Amyloid β-Protein Production in Human Neuronal NT2N Cells (*) (1995) (194)
Phosphorylated alpha-synuclein is ubiquitinated in alpha-synucleinopathy lesions. (2002) (191)
Targeting Amyloid-β Peptide (Aβ) Oligomers by Passive Immunization with a Conformation-selective Monoclonal Antibody Improves Learning and Memory in Aβ Precursor Protein (APP) Transgenic Mice* (2006) (188)
Absence of the Mid-sized Neurofilament Subunit Decreases Axonal Calibers, Levels of Light Neurofilament (NF-L), and Neurofilament Content (1998) (186)
Intracellular APP Processing and Aβ Production in Alzheimer Disease (1999) (183)
Role of alpha-synuclein carboxy-terminus on fibril formation in vitro. (2003) (181)
Formation of α-synuclein Lewy neurite–like aggregates in axons impedes the transport of distinct endosomes (2014) (179)
Inhibition of tau fibrillization by oleocanthal via reaction with the amino groups of tau (2009) (177)
BACE1 activity is modulated by cell-associated sphingosine-1-phosphate (2011) (170)
Amyloids and Are Generated Intracellularly in Cultured Human Neurons and Their Secretion Increases with Maturation (*) (1996) (169)
Effects of Oxidative and Nitrative Challenges on α-Synuclein Fibrillogenesis Involve Distinct Mechanisms of Protein Modifications* (2003) (168)
β-Secretase Processing in the Trans-Golgi Network Preferentially Generates Truncated Amyloid Species That Accumulate in Alzheimer's Disease Brain* (2002) (166)
Paired helical filament tau (PHFtau) in Niemann-Pick type C disease is similar to PHFtau in Alzheimer's disease (2004) (163)
Alpha-synuclein-induced aggregation of cytoplasmic vesicles in Saccharomyces cerevisiae. (2007) (157)
Requirement of Heavy Neurofilament Subunit in the Development of Axons with Large Calibers (1998) (152)
Unique Alzheimer's disease paired helical filament specific epitopes involve double phosphorylation at specific sites. (1997) (152)
Phosphorylation of neurofilament proteins and chromatolysis following transection of rat sciatic nerve (1987) (151)
A precipitating role for truncated alpha-synuclein and the proteasome in alpha-synuclein aggregation: implications for pathogenesis of Parkinson disease. (2005) (150)
The unfolded protein response is activated in disease-affected brain regions in progressive supranuclear palsy and Alzheimer’s disease (2013) (143)
Characterization of two VQIXXK motifs for tau fibrillization in vitro. (2006) (141)
Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice. (2006) (140)
γ-Synuclein Promotes Cancer Cell Survival and Inhibits Stress- and Chemotherapy Drug-induced Apoptosis by Modulating MAPK Pathways* (2002) (137)
Spread of aggregates after olfactory bulb injection of α-synuclein fibrils is associated with early neuronal loss and is reduced long term (2017) (135)
BACE overexpression alters the subcellular processing of APP and inhibits Aβ deposition in vivo (2005) (135)
Modeling Parkinson’s disease pathology by combination of fibril seeds and α-synuclein overexpression in the rat brain (2017) (134)
Patient-derived frontotemporal lobar degeneration brain extracts induce formation and spreading of TDP-43 pathology in vivo (2018) (132)
Novel β-Secretase Cleavage of β-Amyloid Precursor Protein in the Endoplasmic Reticulum/Intermediate Compartment of NT2N Cells (1997) (128)
Ubiquitination of α-Synuclein Is Not Required for Formation of Pathological Inclusions in α-Synucleinopathies (2003) (128)
Glu11 site cleavage and N-terminally truncated A beta production upon BACE overexpression. (2002) (126)
Best Practices for Generating and Using Alpha-Synuclein Pre-Formed Fibrils to Model Parkinson’s Disease in Rodents (2018) (125)
Human and rodent Alzheimer beta-amyloid peptides acquire distinct conformations in membrane-mimicking solvents. (1993) (124)
Interactions between Hsp70 and the hydrophobic core of alpha-synuclein inhibit fibril assembly. (2008) (124)
Molecular and Biological Compatibility with Host Alpha-Synuclein Influences Fibril Pathogenicity. (2016) (123)
Alzheimer disease tangles share immunological similarities with multiphosphorylation repeats in the two large neurofilament proteins. (1988) (122)
Monoclonal antibodies recognize individual neurofilament triplet proteins. (1982) (118)
Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers (2017) (117)
Myosin Va binding to neurofilaments is essential for correct myosin Va distribution and transport and neurofilament density (2002) (115)
Pin1 has opposite effects on wild-type and P301L tau stability and tauopathy. (2008) (112)
Selective imaging of internalized proteopathic α-synuclein seeds in primary neurons reveals mechanistic insight into transmission of synucleinopathies (2017) (108)
Degradative organelles containing mislocalized α- and β-synuclein proliferate in presenilin-1 null neurons (2004) (105)
Activation of a PP2A-like phosphatase and dephosphorylation of tau protein characterize onset of the execution phase of apoptosis. (1998) (105)
A “Two-hit” Hypothesis for Inclusion Formation by Carboxyl-terminal Fragments of TDP-43 Protein Linked to RNA Depletion and Impaired Microtubule-dependent Transport* (2011) (103)
Presenilins are not required for Aβ42 production in the early secretory pathway (2002) (102)
Cleavage of α-Synuclein by Calpain: Potential Role in Degradation of Fibrillized and Nitrated Species of α-Synuclein† (2005) (98)
Fibrillization of alpha-synuclein and tau in familial Parkinson's disease caused by the A53T alpha-synuclein mutation. (2004) (98)
Neurofilament Subunits are Integral Components of Synapses and Modulate Neurotransmission and Behavior In Vivo (2015) (97)
Identification of aminothienopyridazine inhibitors of tau assembly by quantitative high-throughput screening. (2009) (96)
Amyloid precursor protein and amyloid beta peptide in human platelets. Role of cyclooxygenase and protein kinase C. (2001) (94)
Functionally distinct isoforms of dynactin are expressed in human neurons. (1996) (88)
Membrane Topology of γ-Secretase Component PEN-2* (2003) (88)
Temporal and topographic relationships between the phosphorylated and nonphosphorylated epitopes of the 200 kDa neurofilament protein during development in vitro (1987) (87)
Differential α-synuclein expression contributes to selective vulnerability of hippocampal neuron subpopulations to fibril-induced toxicity (2018) (86)
Neuronal localization of the TNFalpha converting enzyme (TACE) in brain tissue and its correlation to amyloid plaques. (2001) (85)
Induction of neurofilament triplet proteins in PC12 cells by nerve growth factor (1982) (81)
Humanization of the entire murine Mapt gene provides a murine model of pathological human tau propagation (2019) (81)
Membrane Topology and Nicastrin-enhanced Endoproteolysis of APH-1, a Component of the γ-Secretase Complex* (2004) (80)
τ Phosphorylation in Human, Primate, and Rat Brain: Evidence that a Pool of τ Is Highly Phosphorylated In Vivo and Is Rapidly Dephosphorylated In Vitro (1994) (80)
Site-specific Dephosphorylation of Tau Protein at Ser/Thr in Response to Microtubule Depolymerization in Cultured Human Neurons Involves Protein Phosphatase 2A (*) (1996) (79)
Amyloids beta40 and beta42 are generated intracellularly in cultured human neurons and their secretion increases with maturation. (1996) (77)
Secretion and Intracellular Generation of Truncated Aβ in β-Site Amyloid-β Precursor Protein-cleaving Enzyme Expressing Human Neurons* (2003) (77)
Solid-phase synthesis of phosphopeptides. (2009) (76)
Distinct cleavage patterns of normal and pathologic forms of alpha-synuclein by calpain I in vitro. (2003) (76)
The Transmembrane Domain Region of Nicastrin Mediates Direct Interactions with APH-1 and the γ-Secretase Complex* (2003) (75)
Cleavage of alpha-synuclein by calpain: potential role in degradation of fibrillized and nitrated species of alpha-synuclein. (2005) (74)
Age and differentiation-related differences in neuron-specific tubulin immunostaining of olfactory sensory neurons. (1994) (73)
Beta-secretase processing in the trans-Golgi network preferentially generates truncated amyloid species that accumulate in Alzheimer's disease brain. (2002) (72)
A distinct ER/IC gamma-secretase competes with the proteasome for cleavage of APP. (2000) (71)
Spatial and temporal expression of phosphorylated and non-phosphorylated forms of neurofilament proteins in the developing nervous system of Xenopus laevis. (1989) (70)
Intrastriatal alpha-synuclein fibrils in monkeys: spreading, imaging and neuropathological changes. (2019) (69)
Alzheimer’s disease tau is a prominent pathology in LRRK2 Parkinson’s disease (2019) (66)
Monoclonal antibodies to a synthetic peptide homologous with the first 28 amino acids of Alzheimer's disease beta-protein recognize amyloid and diverse glial and neuronal cell types in the central nervous system. (1989) (65)
The environmental toxin arsenite induces tau hyperphosphorylation. (2002) (62)
Light and electron microscopic immunolocalization of presenilin 1 in abnormal muscle fibers of patients with sporadic inclusion-body myositis and autosomal-recessive inclusion-body myopathy. (1998) (61)
Intracellular APP processing and A beta production in Alzheimer disease. (1999) (60)
The dynamics of nerve growth factor-induced neurofilament and vimentin filament expression and organization in PC12 cells (1984) (60)
Microtubule destabilization and neurofilament phosphorylation precede dendritic sprouting after close axotomy of lamprey central neurons. (1991) (60)
Staging of neurofibrillary degeneration caused by human tau overexpression in a unique cellular model of human tauopathy. (2001) (59)
Dityrosine cross-linking promotes formation of stable α-synuclein polymers (2000) (59)
Differential Effects of the Swedish Mutant Amyloid Precursor Protein on β-Amyloid Accumulation and Secretion in Neurons and Nonneuronal Cells* (1997) (55)
Genome-wide, high-content siRNA screening identifies the Alzheimer’s genetic risk factor FERMT2 as a major modulator of APP metabolism (2016) (55)
2,5-Hexanedione neuropathy is associated with the covalent crosslinking of neurofilament proteins. (1986) (55)
α-Synuclein (αSyn) Preformed Fibrils Induce Endogenous αSyn Aggregation, Compromise Synaptic Activity and Enhance Synapse Loss in Cultured Excitatory Hippocampal Neurons (2019) (53)
Assessment of immunological properties of neurofilament triplet proteins (1981) (53)
Structural similarities and differences between neurofilament proteins from five different species as revealed using monoclonal antibodies (1986) (51)
Selective Motor Neuron Resistance and Recovery in a New Inducible Mouse Model of TDP-43 Proteinopathy (2016) (50)
Sensitive fluorescence polarization technique for rapid screening of alpha-synuclein oligomerization/fibrillization inhibitors. (2007) (47)
Accumulation of Intracellular Amyloid-β Peptide (Aβ 1–40) in Mucopolysaccharidosis Brains (1999) (47)
Glial cells of the lamprey nervous system contain keratin‐like proteins (1995) (46)
Dramatic Increase of the RNA Editing for Glutamate Receptor Subunits During Terminal Differentiation of Clonal Human Neurons (1997) (44)
Antibody labeling of bovine neurofilaments: implications on the structure of neurofilament sidearms. (1991) (44)
Presenilin modulates Pen-2 levels posttranslationally by protecting it from proteasomal degradation. (2004) (42)
Secretion and intracellular generation of truncated Abeta in beta-site amyloid-beta precursor protein-cleaving enzyme expressing human neurons. (2003) (42)
Alzheimer disease A68 proteins injected into rat brain induce codeposits of beta-amyloid, ubiquitin, and alpha 1-antichymotrypsin. (1993) (41)
An insoluble frontotemporal lobar degeneration-associated TDP-43 C-terminal fragment causes neurodegeneration and hippocampus pathology in transgenic mice. (2015) (41)
Neurofilament protein abnormalities in PC12 cells: comparison with neurofilament proteins of normal cultured rat sympathetic neurons (1985) (40)
Sex-specific genetic predictors of Alzheimer’s disease biomarkers (2018) (40)
Inhibition of axonal development after injection of neurofilament antibodies into a Xenopus laevis embryo (1991) (40)
Modulating TRADD to restore cellular homeostasis and inhibit apoptosis (2020) (38)
Transcriptomic Changes Due to Cytoplasmic TDP-43 Expression Reveal Dysregulation of Histone Transcripts and Nuclear Chromatin (2015) (38)
Slow Progressive Accumulation of Oligodendroglial Alpha-Synuclein (α-Syn) Pathology in Synthetic α-Syn Fibril-Induced Mouse Models of Synucleinopathy. (2019) (38)
Endoproteolysis of β-Secretase (β-Site Amyloid Precursor Protein-cleaving Enzyme) within Its Catalytic Domain (2003) (36)
Retinoic acid induction of calcium channel expression in human NT2N neurons. (1998) (36)
Characterization of antisera raised against cultured rat sympathetic neurons (1980) (34)
LRRK2 inhibition does not impart protection from α-synuclein pathology and neuron death in non-transgenic mice (2019) (32)
Accumulation of intracellular amyloid-beta peptide (A beta 1-40) in mucopolysaccharidosis brains. (1999) (31)
Unbiased Proteomics of Early Lewy Body Formation Model Implicates Active Microtubule Affinity-Regulating Kinases (MARKs) in Synucleinopathies (2017) (30)
Spectroscopic evidence that monoclonal antibodies recognize the dominant conformation of medium-sized synthetic peptides. (1994) (30)
Identification of neural and adrenal medullary surface membrane glycoproteins recognized by antisera to cultured rat sympathetic neurons and PC12 pheochromocytoma cells (1981) (30)
Is amyloid deposition in Alzheimer's disease preceded by an environment-induced double conformational transition? (1989) (30)
The effects of aspartic acid-bond isomerization on in vitro properties of the amyloid beta-peptide as modeled with N-terminal decapeptide fragments. (2009) (29)
The Differential Role of Protein Kinase C Isozyme in the Rapid Induction of Neurofilament Phosphorylation by Nerve Growth Factor and Phorbol Esters in PC12 Cells (1991) (29)
Neuronal activity modulates alpha-synuclein aggregation and spreading in organotypic brain slice cultures and in vivo (2020) (28)
Reversed-phase high-performance liquid chromatographic separation of synthetic phosphopeptide isomers. (1990) (28)
Novel monoclonal antibodies to normal and pathologically altered human TDP-43 proteins (2014) (27)
A "Clickable" Photoconvertible Small Fluorescent Molecule as a Minimalist Probe for Tracking Individual Biomolecule Complexes. (2019) (27)
Expression of human mid-sized neurofilament subunit in transgenic mice. (1992) (27)
Novel b-Secretase Cleavage of b-Amyloid Precursor Protein in the Endoplasmic Reticulum / Intermediate Compartment of NT 2 N Cells (1997) (26)
Comparison of strategies for non-perturbing labeling of α-synuclein to study amyloidogenesis. (2016) (26)
Constitutively active Akt inhibits trafficking of amyloid precursor protein and amyloid precursor protein metabolites through feedback inhibition of phosphoinositide 3-kinase. (2009) (24)
GFP-Mutant Human Tau Transgenic Mice Develop Tauopathy Following CNS Injections of Alzheimer's Brain-Derived Pathological Tau or Synthetic Mutant Human Tau Fibrils (2017) (24)
Endoproteolysis of beta-secretase (beta-site amyloid precursor protein-cleaving enzyme) within its catalytic domain. A potential mechanism for regulation. (2003) (22)
Long-term cultures of neurons from adult frog brain express GABA and glutamate-activated channels. (1989) (22)
Drosophila Ref1/ALYREF regulates transcription and toxicity associated with ALS/FTD disease etiologies (2019) (20)
Expression of foreign proteins in a human neuronal system. (1994) (18)
Differential effects of the swedish mutant amyloid precursor protein on beta-amyloid accumulation and secretion in neurons and nonneuronal cells. (1998) (18)
Distinct brain‐derived TDP‐43 strains from FTLD‐TDP subtypes induce diverse morphological TDP‐43 aggregates and spreading patterns in vitro and in vivo (2021) (15)
Functional Consequences of α-Synuclein Tyrosine Nitration (2004) (15)
In vitro amplification of pathogenic tau conserves disease-specific bioactive characteristics (2021) (15)
High copy wildtype human 1N4R tau expression promotes early pathological tauopathy accompanied by cognitive deficits without progressive neurofibrillary degeneration (2015) (15)
Functions of neurofilaments in synapses (2015) (13)
Pharmacokinetic differences between 111In- and 125I-Labeled cationized monoclonal antibody against β-Amyloid in mouse and dog (1995) (13)
Synthesis and characterization of high affinity fluorogenic α-synuclein probes. (2020) (13)
Immunological and conformation characterization of a phosphorylated immunodominant epitope on the paired helical filaments found in Alzheimer's disease. (1992) (13)
Amyloid Precursor Protein and Amyloid β Peptide in Human Platelets (2001) (12)
Identification of a nanomolar affinity α-synuclein fibril imaging probe by ultra-high throughput in silico screening† †Electronic supplementary information (ESI) available: In silico compound screening, binding assays, chemical synthesis, photo-crosslinking and fibril analysis. See DOI: 10.1039/d0sc (2020) (12)
Distinct presenilin-dependent and presenilin-independent gamma-secretases are responsible for total cellular Abeta production. (2003) (11)
Conformation-selective tau monoclonal antibodies inhibit tau pathology in primary neurons and a mouse model of Alzheimer’s disease (2020) (11)
Vaccinia virus serves as an efficient vector for expressing heterologous proteins in human NTera 2 neurons (1996) (9)
Amyloid Precursor Protein and Amyloid b Peptide in Human Platelets ROLE OF CYCLOOXYGENASE AND PROTEIN KINASE C* (2001) (8)
Cytotoxic Effect of β‐Amyloid on a Human Differentiated Neuron Is Not Mediated by Cytoplasmic Ca2+ Accumulation (1998) (8)
Quantifying Aβ(1-40) and Aβ (1-42) Using Sandwich-ELISA. (2000) (5)
Poly (ADP-ribose) induces α-synuclein aggregation in neuronal-like cells and interacts with phosphorylated α-synuclein in post mortem PD samples (2020) (5)
Beta-secretase revealed: starting gate for race to novel therapies for Alzheimer's disease. (2000) (4)
A neutralizing monoclonal antibody binds to an epitope near the amino terminus of murine granulocyte-macrophage colony-stimulating factor. (1991) (4)
MONOCLONAL ANTIBODIES RECOGNIZE INDIVIDUAL NEUROFILAMENT TRIPLET PROTEINS: 38 (1982) (3)
Tracking tau fibrillogenesis and consequent primary phagocytosis of neurons mediated by microglia in a living tauopathy model (2020) (2)
Domain structure of neurofilament subunits as revealed by monoclonal antibodies (1985) (2)
Mechanisms of oxidative damage in neurodegenerative synucleinopathies (2000) (1)
Reversible beta-pleated sheet formation of a phosphorylated synthetic tau peptide. (1992) (1)
BIOSYNTHESIS OF APP AND Aβ: MULTIPLE PATHWAYS FOR THE GENERATION OF INTRACELLULAR Aβ (1998) (1)
Correction: Comparison of strategies for non-perturbing labeling of α-synuclein to study amyloidogenesis. (2016) (0)
ALZHEIMER A68 PROTEINS INJECTED INTO RAT BRAIN RESIST RAPID PROTEOLYSIS AND INDUCE CO-DEPOSITION OF ß-AMYLOID PEPTIDES (1993) (0)
Modulating TRADD to restore cellular homeostasis and inhibit apoptosis (2020) (0)
Humanneurons derived fromateratocarcinoma cell lineexpress solely the695-amino acidamyloid precursor protein andproduce intracellular (8-amyloid orA4peptides (1993) (0)
147 INDUCTION AND DIFFERENTIAL LOCALIZATON OF NEUROFILAMENT PROTEINS IN CULTURED RAT PC12 PHECHROMOCYTOMA CELLS AFTER EXPOSURE TO NGF (1981) (0)
Atomic-resolution structure of alpha-synuclein fibrils (2016) (0)
Expression andanalysis ofpresenilin 1inahumanneuronal system: Localization incellbodiesanddendrites (Alzheimer disease/presenilins/amyloid precursor protein/amyloid) (1996) (0)
P1-302 Implications of dopamine-induced modificationsof alpha-synuclein protein in the pathogenesis of Parkinson's disease (2004) (0)
well as regulated genes be identified? high store-operated calcium entry: can regulatory as Gene expression profiles in HEK-293 cells with low or (2015) (0)
Structural and biochemical comparison between young and aged rat neurofilaments (1996) (0)
Synthetic alpha-synuclein fibrils cause mitochondrial impairment and selective dopamine neurodegeneration in part via iNOS-mediated nitric oxide production (2017) (0)
Alzheimer's disease: Targeting of Nicastrin to sub-cellular compartments and its influence on G-secretase complex activity (2005) (0)
Protein arginylation targets alpha synuclein, facilitates normal brain health, and prevents neurodegeneration (2017) (0)

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