Vito Quaranta
#142,318
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Biochemist
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Vito Quarantabiology Degrees
Biology
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Biochemistry
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#1715
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Biology
Vito Quaranta's Degrees
- PhD Biochemistry University of California, San Francisco
- Bachelors Chemistry University of California, Berkeley
Why Is Vito Quaranta Influential?
(Suggest an Edit or Addition)Vito Quaranta's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5. (1997) (1298)
- A simplified laminin nomenclature. (2005) (849)
- Integrin cytoplasmic domains mediate inside-out signal transduction (1994) (734)
- Tumor Morphology and Phenotypic Evolution Driven by Selective Pressure from the Microenvironment (2006) (707)
- Role of Cell Surface Metalloprotease Mt1-Mmp in Epithelial Cell Migration over Laminin-5 (2000) (668)
- Intracellular transport of class II MHC molecules directed by invariant chain (1990) (551)
- Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data (2019) (485)
- Integrative mathematical oncology (2008) (409)
- Cooperative interactions of laminin 5 gamma2 chain, matrix metalloproteinase-2, and membrane type-1-matrix/metalloproteinase are required for mimicry of embryonic vasculogenesis by aggressive melanoma. (2001) (378)
- Kisspeptin-10, a KiSS-1/metastin-derived decapeptide, is a physiological invasion inhibitor of primary human trophoblasts (2004) (344)
- A novel vitronectin receptor integrin (α v β x ) is responsible for distinct adhesive properties of carcinoma cells (1989) (311)
- Binding to EGF receptor of a laminin-5 EGF-like fragment liberated during MMP-dependent mammary gland involution (2003) (299)
- Epithelial integrin alpha 6 beta 4: complete primary structure of alpha 6 and variant forms of beta 4 (1990) (285)
- A novel integrin (alpha E beta 4) from human epithelial cells suggests a fourth family of integrin adhesion receptors. (1989) (261)
- Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities. (2021) (253)
- Immunohistochemical localization of integrins in the normal, hyperplastic, and neoplastic breast. Correlations with their functions as receptors and cell adhesion molecules. (1991) (253)
- EXPRESSION OF Ia‐LIKE ANTIGENS IN NORMAL HUMAN NONLYMPHOID TISSUES (1981) (232)
- Cell type-specific integrin variants with alternative alpha chain cytoplasmic domains. (1991) (216)
- Polarized integrin mediates human keratinocyte adhesion to basal lamina. (1990) (214)
- Laminin-5 and hemidesmosomes: role of the alpha 3 chain subunit in hemidesmosome stability and assembly. (1996) (204)
- Tales from the crypt[ic] sites of the extracellular matrix. (2003) (203)
- Tumor cell α3β1 integrin and vascular laminin-5 mediate pulmonary arrest and metastasis (2004) (193)
- A function for the integrin alpha 6 beta 4 in the hemidesmosome. (1991) (185)
- Complete amino acid sequence of a novel integrin beta subunit (beta 6) identified in epithelial cells using the polymerase chain reaction. (1990) (173)
- Surface relocation of alpha 6 beta 4 integrins and assembly of hemidesmosomes in an in vitro model of wound healing (1991) (173)
- Rapid Disruption of an Astrocyte Interaction With the Extracellular Matrix Mediated by Integrin α6β4 During Focal Cerebral Ischemia/Reperfusion (1997) (163)
- The major laminin receptor of mouse embryonic stem cells is a novel isoform of the alpha 6 beta 1 integrin (1991) (161)
- Laminin receptors in the retina: sequence analysis of the chick integrin alpha 6 subunit. Evidence for transcriptional and posttranslational regulation (1991) (158)
- Beta 4 integrin expression in myelinating Schwann cells is polarized, developmentally regulated and axonally dependent. (1994) (158)
- A new isoform of the laminin receptor integrin alpha 7 beta 1 is developmentally regulated in skeletal muscle. (1993) (154)
- Serologic and immunochemical characterization of the specificity of four monoclonal antibodies to distinct antigenic determinants expressed on subpopulations of human Ia-like antigens. (1981) (149)
- Cadherin-Bound β-Catenin Feeds into the Wnt Pathway upon Adherens Junctions Dissociation: Evidence for an Intersection between β-Catenin Pools (2009) (140)
- Clinically Relevant Modeling of Tumor Growth and Treatment Response (2013) (140)
- Transforming growth factor beta induces clustering of HER2 and integrins by activating Src-focal adhesion kinase and receptor association to the cytoskeleton. (2009) (132)
- Human Hepatocellular Carcinoma (HCC) Cells Require Both α3β1 Integrin and Matrix Metalloproteinases Activity for Migration and Invasion (2001) (125)
- Membrane-type Matrix Metalloproteinase-1 (MT1-MMP) Is a Processing Enzyme for Human Laminin γ2 Chain* (2005) (124)
- Remodeling of the Microenvironment by Aggressive Melanoma Tumor Cells (2003) (119)
- Inhibitory Role of α6β4-Associated Erbb-2 and Phosphoinositide 3-Kinase in Keratinocyte Haptotactic Migration Dependent on α3β1 Integrin (2001) (119)
- Purification of immunologically functional subsets of human Ia-like antigens on a monoclonal antibody (Q5/13) immunoadsorbent. (1980) (116)
- Normalizing DNA microarray data. (2002) (115)
- Expression and function of alpha(v)beta(3) and alpha(v)beta(5) integrins in the developing pancreas: roles in the adhesion and migration of putative endocrine progenitor cells. (2000) (113)
- Epithelial cell motility on laminin-5: regulation by matrix assembly, proteolysis, integrins and erbB receptors. (2004) (109)
- Mathematical modeling of cancer: the future of prognosis and treatment. (2005) (107)
- Matrix metalloproteinases process the laminin-5 γ2-chain and regulate epithelial cell migration (2003) (104)
- Quantifying Drug Combination Synergy along Potency and Efficacy Axes. (2019) (104)
- Chloroquine affects biosynthesis of Ia molecules by inhibiting dissociation of invariant (gamma) chains from alpha-beta dimers in B cells (1985) (102)
- A novel circular invasion assay mimics in vivo invasive behavior of cancer cell lines and distinguishes single-cell motility in vitro (2008) (102)
- The LG3 Module of Laminin-5 Harbors a Binding Site for Integrin α3β1 That Promotes Cell Adhesion, Spreading, and Migration* (2001) (101)
- Microenvironment driven invasion: a multiscale multimodel investigation (2009) (98)
- Fractional Proliferation: A method to deconvolve cell population dynamics from single-cell data (2012) (96)
- Expression and Function of αvβ3 and αvβ5 Integrins in the Developing Pancreas (2000) (95)
- A human Ia cytoplasmic determinant located on multiple forms of invariant chain (gamma, gamma 2, gamma 3). (1984) (94)
- An off-lattice hybrid discrete-continuum model of tumor growth and invasion. (2010) (93)
- Laminin-332 Is a Substrate for Hepsin, a Protease Associated with Prostate Cancer Progression* (2008) (93)
- Distribution of the alpha 1-alpha 6 integrin subunits in human developing and term placenta. (1991) (92)
- Involvement of laminin binding integrins and laminin-5 in branching morphogenesis of the ureteric bud during kidney development. (2001) (88)
- An unbiased metric of antiproliferative drug effect in vitro (2016) (85)
- A spatial model of tumor-host interaction: application of chemotherapy. (2008) (85)
- Discrete Proteolysis of Focal Contact and Adherens Junction Components in Porphyromonas gingivalis-Infected Oral Keratinocytes: a Strategy for Cell Adhesion and Migration Disabling (2002) (81)
- Proteolytic processing of laminin‐5 by MT1‐MMP in tissues and its effects on epithelial cell morphology (2004) (81)
- Epithelial integrins. (1990) (80)
- Four Ia invariant chain forms derive from a single gene by alternate splicing and alternate initiation of transcription/translation (1987) (79)
- Defining the role of laminin-332 in carcinoma. (2009) (78)
- Rapid disruption of an astrocyte interaction with the extracellular matrix mediated by integrin alpha 6 beta 4 during focal cerebral ischemia/reperfusion. (1997) (78)
- Human hepatocellular carcinoma (HCC) cells require both alpha3beta1 integrin and matrix metalloproteinases activity for migration and invasion. (2001) (78)
- Invasion emerges from cancer cell adaptation to competitive microenvironments: quantitative predictions from multiscale mathematical models. (2008) (77)
- A Monoclonal Antibody Inhibits Adhesion to Fibronectin and Vitronectin of a Colon Carcinoma Cell Line and Recognizes the Integrins αvβ3, αvβ5, and αvβ6 (1994) (77)
- Expression of matrix metalloprotease-2-cleaved laminin-5 in breast remodeling stimulated by sex steroids. (1999) (77)
- The internal affairs of an integrin. (1991) (77)
- αv Integrins mediate adhesion and migration of breast carcinoma cell lines (2004) (76)
- Coating of titanium alloy with soluble laminin-5 promotes cell attachment and hemidesmosome assembly in gingival epithelial cells: potential application to dental implants. (1997) (76)
- Rapid spreading and mature hemidesmosome formation in HaCaT keratinocytes induced by incubation with soluble laminin-5r. (1995) (76)
- Morphogenetic effects of soluble laminin-5 on cultured epithelial cells and tissue explants. (1996) (76)
- Network Analysis of the Focal Adhesion to Invadopodia Transition Identifies a PI3K-PKCα Invasive Signaling Axis (2012) (75)
- Integrin distributions in renal cell carcinomas of various grades of malignancy. (1992) (74)
- Co-expression network analysis identifies Spleen Tyrosine Kinase (SYK) as a candidate oncogenic driver in a subset of small-cell lung cancer (2013) (73)
- Monoclonal antibodies to HLA-A,B, and Ia-like antigens inhibit colony formation by human myeloid progenitor cells. (1980) (73)
- Localization and possible role of two different alpha v beta 3 integrin conformations in resting and resorbing osteoclasts. (2002) (72)
- Migration of breast epithelial cells on Laminin-5: differential role of integrins in normal and transformed cell types (1998) (72)
- Activation of the Integrin Involves a Discrete Cation-binding Site That Regulates Conformation (*) (1996) (72)
- Integrin α6Aβ1 Induces CD81-dependent Cell Motility without Engaging the Extracellular Matrix Migration Substrate (1997) (70)
- Activation of alphav beta3 integrin on human osteoclast-like cells stimulates adhesion and migration in response to osteopontin. (1998) (69)
- Ia-like antigens on human T lymphocytes: relationship to other surface markers, role in mixed lymphocyte reactions, and structural profile. (1980) (69)
- Establishment and Validation of Computational Model for MT1-MMP Dependent ECM Degradation and Intervention Strategies (2012) (68)
- Toward a science of tumor forecasting for clinical oncology. (2015) (68)
- Microenvironmental independence associated with tumor progression. (2009) (62)
- Transgenic HLA-DRα faithfully reconstitutes IE-controlled immune functions and induces cross-tolerance to Eα in Eα 0 mutant mice (1989) (60)
- New approaches to small cell lung cancer therapy : from the laboratory to the clinic. (2020) (60)
- The contribution of age structure to cell population responses to targeted therapeutics. (2011) (58)
- Systems-level network modeling of Small Cell Lung Cancer subtypes identifies master regulators and destabilizers (2018) (58)
- A mechanically coupled reaction–diffusion model that incorporates intra-tumoural heterogeneity to predict in vivo glioma growth (2017) (57)
- Novel Hybrid Phenotype Revealed in Small Cell Lung Cancer by a Transcription Factor Network Model That Can Explain Tumor Heterogeneity. (2017) (56)
- Human Mammary Epithelial Cells Exhibit a Bimodal Correlated Random Walk Pattern (2010) (55)
- A novel vitronectin receptor integrin (alpha v beta x) is responsible for distinct adhesive properties of carcinoma cells. (1989) (55)
- The Activation State of the Integrin Affects Outside-in Signals Leading to Cell Spreading and Focal Adhesion Kinase Phosphorylation (*) (1995) (55)
- Modelling of Cancer Growth, Evolution and Invasion: Bridging Scales and Models (2007) (54)
- Defining signal thresholds in DNA microarrays: exemplary application for invasive cancer (2002) (54)
- MHC class II molecules and immunoglobulins on peripheral blood lymphocytes of the bottlenosed dolphin, Tursiops truncatus. (1992) (53)
- Tissue remodelling in liver diseases. (2003) (53)
- Immunolocalization of Integrin α6β4 in Mouse Junctional Epithelium Suggests an Anchoring Function to both the Internal and the External Basal Lamina (1992) (52)
- Matrix metalloproteinases process the laminin-5 gamma 2-chain and regulate epithelial cell migration. (2003) (52)
- Altered expression of basement membrane proteins and their integrin receptors in lichen planus: possible pathogenetic role of gelatinases A and B. (1996) (51)
- Changes in expression of monoclonal antibody epitopes on laminin-5r induced by cell contact. (1996) (51)
- Thrombospondin-1 acts as a ligand for CD148 tyrosine phosphatase (2012) (50)
- DNA copy number aberrations in small-cell lung cancer reveal activation of the focal adhesion pathway (2010) (49)
- Cell Migration through Extracellular Matrix (2000) (48)
- Linking Changes in Epithelial Morphogenesis to Cancer Mutations Using Computational Modeling (2010) (47)
- Alphav integrins mediate adhesion and migration of breast carcinoma cell lines. (1998) (47)
- Laminin 5 in the Human Thymus: Control of T Cell Proliferation via α6β4 Integrins (1999) (44)
- De novo identification of tumor-specific internalizing human antibody-receptor pairs by phage-display methods. (2003) (44)
- Predicting in vivo glioma growth with the reaction diffusion equation constrained by quantitative magnetic resonance imaging data (2015) (44)
- Inhibitors (1991) (44)
- Motility cues in the tumor microenvironment. (2002) (43)
- Molecular cloning and characterization of CD4 in an aquatic mammal, the white whale Delphinapterus leucas (1999) (43)
- Six monoclonal antibodies to human pancreatic cancer antigens. (1987) (42)
- Charting the Fragmented Landscape of Drug Synergy. (2020) (42)
- Dependence On Glycolysis Sensitizes BRAF-mutated Melanomas For Increased Response To Targeted BRAF Inhibition (2017) (40)
- Immunoloealization of integrins in the normal and neoplastic colonic epithelium (1993) (40)
- The human invariant chain is the core protein of the human class II- associated proteoglycan (1986) (39)
- Ia-like antigens on freshly explanted human melanoma. (1981) (38)
- Binding of monoclonal antibody (4F2) to its cell surface antigen on dispersed adenomatous parathyroid cells raises cytosolic calcium and inhibits parathyroid hormone secretion. (1987) (37)
- Expression of Ia-like antigens on the vasculature of human kidney. (1981) (37)
- A splice variant of alpha 6 integrin is associated with malignant conversion in mouse skin tumorigenesis. (1995) (36)
- Integrin α6β4-erbB2 Complex Inhibits Haptotaxis by Up-regulating E-cadherin Cell-Cell Junctions in Keratinocytes* (2005) (36)
- A radioimmunometric antibody-binding assay for evaluation of xenoantisera to melanoma-associated antigens. (1979) (35)
- Quantitative measurement of alpha 6 beta 1 and alpha 6 beta 4 integrin internalization under cross-linking conditions: a possible role for alpha 6 cytoplasmic domains. (1994) (34)
- A monoclonal antibody inhibits adhesion to fibronectin and vitronectin of a colon carcinoma cell line and recognizes the integrins alpha v beta 3, alpha v beta 5, and alpha v beta 6. (1994) (33)
- Influence of cell cycle phase on apparent diffusion coefficient in synchronized cells detected using temporal diffusion spectroscopy (2011) (33)
- A Predictive Mathematical Modeling Approach for the Study of Doxorubicin Treatment in Triple Negative Breast Cancer (2017) (32)
- Gradient of Integrin α6A Distribution in the Myocardium During Early Heart Development (1995) (32)
- Cancer Invasion: Watch Your Neighbourhood! (2003) (31)
- Laminin‐332 cleavage by matriptase alters motility parameters of prostate cancer cells (2011) (31)
- Evidence that laminin-5 is a component of the tooth surface internal basal lamina, supporting epithelial cell adhesion. (1999) (29)
- Dissection of the osteogenic effects of laminin-332 utilizing specific LG domains: LG3 induces osteogenic differentiation, but not mineralization. (2008) (29)
- Characterization of a Tight Molecular Complex between Integrin α6β4 and Laminin-5 Extracellular Matrix☆☆☆ (1998) (29)
- MT1-MMP-mediated basement membrane remodeling modulates renal development. (2010) (29)
- Laminin‐332–β1 integrin interactions negatively regulate invadopodia (2009) (28)
- Ammonium chloride interferes with a distinct step in the biosynthesis and cell surface expression of human melanoma-type chondroitin sulfate proteoglycan. (1986) (28)
- Precision Medicine with Imprecise Therapy: Computational Modeling for Chemotherapy in Breast Cancer1 (2018) (27)
- Correction: Novel Hybrid Phenotype Revealed in Small Cell Lung Cancer by a Transcription Factor Network Model That Can Explain Tumor Heterogeneity. (2017) (27)
- New Approaches to SCLC Therapy: From the Laboratory to the Clinic (2020) (27)
- A Nonquiescent "Idling" Population State in Drug-Treated, BRAF-Mutated Melanoma. (2018) (27)
- Psoriatic lesions in patients with chronic liver disease are distinct from psoriasis vulgaris lesions, as judged on basis of integrin adhesion receptors (1994) (26)
- Nest expansion assay: a cancer systems biology approach to in vitro invasion measurements (2009) (26)
- Model-controlled hydrodynamic focusing to generate multiple overlapping gradients of surface-immobilized proteins in microfluidic devices. (2008) (26)
- DNA microarrays: a novel approach to investigate genomics in trophoblast invasion--a review. (2000) (26)
- Development of High-Throughput Quantitative Assays for Glucose Uptake in Cancer Cell Lines (2011) (25)
- Structure of the human Ia-associated invariant (gamma)-chain gene: identification of 5' sequences shared with major histocompatibility complex class II genes. (1986) (25)
- The invariant chain is a phosphorylated subunit of class II molecules. (1989) (25)
- Trait variability of cancer cells quantified by high-content automated microscopy of single cells. (2009) (25)
- Biophysical Modeling of In Vivo Glioma Response After Whole-Brain Radiation Therapy in a Murine Model of Brain Cancer. (2017) (25)
- Dispersal of epithelial cancer cell colonies by lysophosphatidic acid (LPA) (2006) (24)
- Activation of the integrin alpha v beta 3 involves a discrete cation-binding site that regulates conformation. (1996) (24)
- An efficient and reliable method for cloning PCR-amplification products: a survey of point mutations in integrin cDNA. (1992) (23)
- Ventricular-Subventricular Zone Contact by Glioblastoma is Not Associated with Molecular Signatures in Bulk Tumor Data (2019) (23)
- The activation state of the integrin alpha IIb beta 3 affects outside-in signals leading to cell spreading and focal adhesion kinase phosphorylation. (1995) (23)
- Integrin alpha6 maintains the structural integrity of the kidney collecting system. (2017) (22)
- Tissue distribution of Ia-like antigens in different species: analysis with monoclonal antibodies. (1981) (22)
- Integrin alpha 6A beta 1 induces CD81-dependent cell motility without engaging the extracellular matrix migration substrate. (1997) (21)
- Quantifying heterogeneity and dynamics of clonal fitness in response to perturbation (2015) (21)
- Human osteoclast-like cells selectively recognize laminin isoforms, an event that induces migration and activates Ca2+ mediated signals. (1996) (21)
- Integrin alpha6beta4-erbB2 complex inhibits haptotaxis by up-regulating E-cadherin cell-cell junctions in keratinocytes. (2005) (21)
- MuSyC is a consensus framework that unifies multi-drug synergy metrics for combinatorial drug discovery (2021) (20)
- Differential regulation of integrins and extracellular matrix binding in epidermal differentiation and squamous tumor progression. (1996) (19)
- Mathematical models of cell phenotype regulation and reprogramming: Make cancer cells sensitive again! (2017) (19)
- Integrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt (2015) (18)
- Metabolic plasticity meets gene regulation (2019) (18)
- A Decreased Ratio of Laminin-332 β3 to γ2 Subunit mRNA is Associated with Poor Prognosis in Colon Cancer (2009) (17)
- ASCL1 represses a SOX9+ neural crest stem-like state in small cell lung cancer (2021) (17)
- The Major Laminin Receptor of Mouse Embryonic Stem Cells Is a Novel Isoform of the a 6 ß 1 Integrin (2002) (16)
- Antibody-induced activation of beta1 integrin receptors stimulates cAMP-dependent migration of breast cells on laminin-5. (2000) (16)
- Author Correction: Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data (2019) (16)
- Isolation of Ia-like antigen-bearing cells from human peripheral lymphocytes through the use of a monoclonal antibody to framework determinants of Ia-like antigens. (1980) (15)
- Serological, functional, and immunochemical characterization of a monoclonal antibody (MoAb Q2/70) to human Ia-like antigens. (1980) (15)
- Natural cytotoxicity and antibody-dependent cellular cytotoxicity of human lymphocytes depleted of HLA-DR bearing cells with monoclonal HLA-DR antibodies. (1980) (15)
- CellAnimation: an open source MATLAB framework for microscopy assays (2012) (15)
- Quantitative measurement of α6β1 and α6β4 integrin internalization under cross-linking conditions: a possible role for α6 cytoplasmic domains (1994) (15)
- Computational investigation of intrinsic and extrinsic mechanisms underlying the formation of carcinoma. (2012) (14)
- Characterization of the specificity of DR monoclonal antibodies. (1979) (14)
- The free and the β2-microglobulin-associated heavy chains of HLA-A, B alloantigens share the antigenic determinant recognized by the monoclonal antibody Q1/28 (2004) (14)
- Integrins and laminins in tissue remodeling. (1997) (14)
- Drug-Tolerant Idling Melanoma Cells Exhibit Theory-Predicted Metabolic Low-Low Phenotype (2019) (14)
- Monoclonal antibody-mediated modulation of parathyroid hormone secretion by dispersed parathyroid cells. (1987) (13)
- Automated Analysis of Cell-Matrix Adhesions in 2D and 3D Environments (2015) (13)
- Immunolocalization of integrin alpha 6 beta 4 in mouse junctional epithelium suggests an anchoring function to both the internal and the external basal lamina. (1992) (13)
- Characterization of Morphological and Cytoskeletal Changes in MCF10A Breast Epithelial Cells Plated on Laminin-5: Comparison with Breast Cancer Cell Line MCF7 (2001) (13)
- Effect of Tunicamycin on the Assembly and Antigenicity of HLA Antigens: Analysis with Monoclonal Antibodies (1981) (13)
- Serologically detectable human melanoma-associated antigens are not genetically linked to HLA-A and B antigens. (1979) (13)
- Sulfated N-linked oligosaccharides in mammalian cells. III. Characterization of a pancreatic carcinoma cell surface glycoprotein with N- and O-sulfate esters on asparagine-linked glycans. (1988) (12)
- Mode of adsorption and orientation of an extracellular matrix protein affect its cell-adhesion-promoting activity. (1998) (12)
- What Lies Beneath: Looking Beyond Tumor Genetics Shows the Complexity of Signaling Networks Underlying Drug Sensitivity (2013) (12)
- The monoclonal xenoantibody Q6/64 recognizes a determinant expressed by certain gene products of the A and B loci of the HLA region (2004) (11)
- An in vitro model of tumor heterogeneity resolves genetic, epigenetic, and stochastic sources of cell state variability (2021) (11)
- Bimodal analysis reveals a general scaling law governing nondirected and chemotactic cell motility. (2010) (11)
- Not all noise is waste (2010) (11)
- Characterization of a tight molecular complex between integrin alpha 6 beta 4 and laminin-5 extracellular matrix. (1998) (11)
- Gradient of integrin alpha 6A distribution in the myocardium during early heart development. (1995) (11)
- Changes in Ia-like antigen expression on malignant human cells (2005) (11)
- Characterization of DR antigens on cultured melanoma cells by using monoclonal antibodies. (1980) (11)
- Archetype tasks link intratumoral heterogeneity to plasticity and cancer hallmarks in small cell lung cancer. (2022) (10)
- Distribution of antigenic determinants recognized by three monoclonal antibodies (Q2/70, Q5/6 and Q5/13) on human Ia-like alloantigens and on their subunits (2005) (10)
- The role of a recombinant fragment of laminin-332 in integrin alpha3beta1-dependent cell binding, spreading and migration. (2010) (10)
- Cancer Hallmarks Define a Continuum of Plastic Cell States between Small Cell Lung Cancer Archetypes (2021) (10)
- Stimulation of human T lymphocytes by PHA-activated autologous T lymphocytes: Analysis of the role of Ia-like antigens with monoclonal antibodies (2005) (9)
- Migration of isogenic cell lines quantified by dynamic multivariate analysis of single-cell motility (2008) (9)
- Derivation and experimental comparison of cell-division probability densities. (2014) (9)
- Rosetting of human T lymphocytes with goat red blood cells: effect of treatment with 2-aminoethylisothiouronium bromide (AET) and comparison with AET treated sheep red blood cells. (1979) (9)
- Epitope mapping of function‐blocking monoclonal antibody CM6 suggests a “weak” integrin binding site on the laminin‐332 LG2 domain (2010) (8)
- Lysis of cultured human melanoma M10 cells by polyclonal xenoantibodies to melanoma-associated antigens. (1981) (8)
- Leveraging Mathematical Modeling to Quantify Pharmacokinetic and Pharmacodynamic Pathways: Equivalent Dose Metric (2019) (8)
- Modeling of Effects of Nutrient Gradients on Cell Proliferation in Microfluidic Bioreactor (2007) (8)
- Lack of DR antigens on human B-lymphocyte-mouse fibroblast hybrids that express HLA-A,B antigens. (1979) (7)
- A recurrent idiotype on monoclonal anti-human Ia antibodies (1982) (7)
- Lysophosphatidic Acid Upregulates Laminin-332 Expression during A431 Cell Colony Dispersal (2010) (7)
- Receptor Association to the Cytoskeleton and Integrins by Activating Src-Focal Adhesion Kinase and Induces Clustering of HER 2 β Transforming Growth Factor (2009) (7)
- An ELISA for detection of DNA-bound carcinogen using a monoclonal antibody to N-acetoxy-2-acetylaminofluorene-modified DNA. (1987) (7)
- Beyond genetics in personalized cancer treatment: assessing dynamics and heterogeneity of tumor responses. (2013) (7)
- Beyond Programmed Death-Ligand 1: B7-H6 Emerges as a Potential Immunotherapy Target in SCLC (2021) (6)
- Use of monoclonal antibodies to investigate immunologic cross-reactivity of histocompatibility antigens from various animal species. (1980) (6)
- ACDC: Automated Cell Detection and Counting for Time-Lapse Fluorescence Microscopy (2020) (6)
- Altered TGF‐α/β signaling drives cooperation between breast cancer cell populations (2016) (6)
- Level of Ia-like antigens on human B and T lymphocytes. (1981) (5)
- Beyond PD-L1: B7-H6 emerges as a potential immunotherapy target in small cell lung cancer. (2021) (5)
- A Consensus Framework Unifies Multi-Drug Synergy Metrics (2019) (5)
- The HLA-class II-associated chondroitin sulfate proteoglycan expressed by class II positive T and monocyte-like cell lines is larger than that expressed by EBV-transformed B-lymphoblastoid cell lines. (1987) (5)
- An Integrative Gene Expression and Mathematical Flux Balance Analysis Identifies Targetable Redox Vulnerabilities in Melanoma Cells (2020) (4)
- Abstract B27: Phenotypic plasticity and heterogeneity in small cell lung cancer (SCLC): Novel molecular subtypes and potential for targeted therapy. (2014) (4)
- Laminins and Cancer Progression (2010) (4)
- Thunor: visualization and analysis of high-throughput dose–response datasets (2019) (4)
- Characterization of Human Null Cells Isolated from Peripheral Lymphocytes by a Simultaneous Double‐Rosetting Procedure (1981) (4)
- Distinctive Functions of α6β4 and Other Integrins in Epithelial Cells (1994) (4)
- A drift-diffusion checkpoint model predicts a highly variable and growth-factor-sensitive portion of the cell cycle G1 phase (2018) (3)
- Structure of the human Ia-associated invariant ( y )-chain gene : Identification of 5 ' sequences shared with major histocompatibility complex class II genes ( genomic library / nucleotide sequence ) (3)
- Integrin Expression and Epithelial Cell Differentiation (1993) (3)
- Small Cell Lung Cancer subtypes identified by systems-level modeling of transcription factor networks (2018) (3)
- Variable Cell Line Pharmacokinetics Contribute to Non-Linear Treatment Response in Heterogeneous Cell Populations (2018) (3)
- Disruption of Redox Balance Enhances the Effects of BRAF-inhibition in Melanoma Cells (2019) (3)
- HLA-DR antigens and mitogenic factors released by PWM-stimulated T lymphocytes share the framework determinant recognized by the monoclonal antibody Q5/13. (1981) (3)
- Conditionally active STAT1 and its functional role in tumor progression and invasion (2006) (3)
- Evidence for a K+ channel requirement in spreading of rat basophilic leukemia cells on fibronectin-coated surfaces. (1996) (3)
- A transcription factor network model explains heterogeneity and reveals a novel hybrid phenotype in Small-Cell Lung Cancer . Authors / Affiliations (2016) (2)
- Multi-Network Modeling of Cancer Cell States (2012) (2)
- Visualization and analysis of high-throughput in vitro dose–response datasets with Thunor (2019) (2)
- Monoclonal and polyclonal xenoantibodies to the HLA-A, B, C antigenic molecular complex do not affect the functional activity of C3 receptors. (1980) (2)
- Dynamics of drug response informs rational combination regimens (2019) (2)
- HLA Polyclonal and Monoclonal Xenoantibodies (1981) (2)
- A unifying framework disentangles genetic, epigenetic, and stochastic sources of drug-response variability in an in vitro model of tumor heterogeneity (2020) (2)
- T Cell Recognition of Major Histocompatibility Complex Antigens in HLA Class II Transgenic Mice (1990) (2)
- ASCL1 represses a latent osteogenic program in small cell lung cancer in multiple cells of origin (2020) (1)
- BIOCHEMICAL AND FUNCTIONAL PROFILES OF TWO UNIQUE MELANOMA ASSOCIATED ANTIGENS (1985) (1)
- Cooperative RNA degradation stabilizes intermediate epithelial-mesenchymal states and supports a phenotypic continuum (2022) (1)
- Cross-reactivity between human and murine lymphocyte antigens (1981) (1)
- Identifying mechanisms driving the early response of triple negative breast cancer patients to neoadjuvant chemotherapy using a mechanistic model integrating in vitro and in vivo imaging data (2022) (1)
- Effect of polyclonal and monoclonal HLA-DR xenoantibodies on xenogeneic mixed lymphocyte reactions (2005) (1)
- Ventricular-Subventricular Zone Contact by Glioblastoma is Not Associated with Molecular Signatures in Bulk Tumor Data (2018) (1)
- Abstract A09: Predicting response to whole brain radiotherapy in a murine model of glioma (2017) (1)
- Measurements of Mean Nuclear and Cell Sizes Using Ultra-Short Diffusion Times (2009) (1)
- Activation of STAT3 through combined SRC and EGFR signaling drives resistance to a mitotic kinesin inhibitor in glioblastoma (2022) (1)
- Tumor cell (cid:1) 3 (cid:2) 1 integrin and vascular laminin-5 mediate pulmonary arrest and metastasis (2004) (1)
- Evidence for Bigfoot? An Investigation of the Mill Creek 'Sasquatch Prints' (2019) (1)
- Organoids as a Systems Platform for SCLC Brain Metastasis (2022) (1)
- Immunodetection of integrins in the normal and neoplastic colon (1992) (1)
- Vanderbilt PC9 cell line exposed to varying concentrations of erlotinib (2014) (0)
- VP29.06: Cell‐free DNA screening for fetal aneuploidy by targeted method based on microarray quantitation as primary test in the average risk population: results from a single European laboratory (2020) (0)
- Abstract 2894: Overcoming intrinsic resistance toBRAF-inhibitors by modulating redox balance inBRAF-mutated melanoma cells (2019) (0)
- Laminin 5 in the Human Thymus: Control of T Cell Proliferation via (cid:97) 6 (cid:98) 4 Integrins (1999) (0)
- Validating mathematical tumor invasion model simulations using xenograft mouse models of cancer invasion. (2007) (0)
- Abstract 670: Molecular basis of the idling state uncovers vulnerabilities suitable to sequential targeting in melanoma (2019) (0)
- Ralph A. Reisfeld, PhD: In Memoriam (1926–2020) (2021) (0)
- Integrative mathematical modeling of cancer invasion. (2006) (0)
- Abstract 3761: Distinct transcriptional programs drive phenotypic heterogeneity in small cell lung cancer (2015) (0)
- Variation of ADC with Cell Cycle Phases : A Study Using Synchronized HL-60 Cells (2009) (0)
- Abstract 3403: A stochastically arising subpopulation of B-RafV600E-expressing melanoma continues division in the presence of vemurafenib. (2013) (0)
- Transduction of mutated or wild type beta-catenin in a naturally beta-catenin nullosomic tumor cell line leads to elevated S100A4/mts-1/metastasin expression (2004) (0)
- Surface Relocation ofA1pha6Beta4 Integrins and Assembly ofHemidesmosomes in an In Vitro Model ofWound Healing (2002) (0)
- CXCR2 expression during melanoma tumorigenesis controls transcriptional programs that facilitate tumor growth (2023) (0)
- The Integrin α 6β4 in Epithelial and Carcinoma Cells (2017) (0)
- Abstract A14: Predicting the response of triple negative breast cancer to doxorubicin (2017) (0)
- Real-time luminescence enables continuous drug–response analysis in adherent and suspension cell lines (2022) (0)
- Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data (2019) (0)
- Tumor DNA Copy Number Alterations Reveal Activation Of The Focal Adhesion Pathway In Small Cell Lung Cancer (2010) (0)
- Mathematical Oncology Microenvironmental Independence Associated with Tumor Progression (2009) (0)
- Evaluation of immune checkpoints in small cell lung cancer: implications for immunotherapy (2020) (0)
- Functional analysis and topography of integrins in human epithelial cells (1990) (0)
- MuSyC dosing of adjuvanted cancer vaccines optimizes antitumor responses (2022) (0)
- Abstract 5216: Gene co-expression network analysis of small cell lung cancer (SCLC) identifies new subclasses and novel therapeutic targets including Src family kinase Fyn and Spleen Tyrosine Kinase Syk. (2013) (0)
- Adaptation-driven Models of Cancer Invasion: Experimental Parameterization and Validation (2008) (0)
- Abstract 2018: Systems biology modeling of cellular radiosensitivity: A heterogeneity signature in the clonogenic assay (2010) (0)
- Functional Analysis of Alpha-6 Integrin Cytoplasinic Domains. (1997) (0)
- DAMD 1794-J-4155 TITLE : Functional Analysis of Alpha-6 Integrin Cytoplasmic Domains (0)
- A heterogeneous drug tolerant persister state in BRAF-mutant melanoma is characterized by ion channel dysregulation and susceptibility to ferroptosis (2022) (0)
- Abstract 4626: Quantifying erlotinib response variability in EGFR-addicted cells. (2013) (0)
- Quantitative Approaches to Heterogeneity and Growth Variability in Cell Populations (2014) (0)
- Binding of Integrins to Laminins (2007) (0)
- Abstract 1845: Sensitivity of PC9 cells to erlotinib is affected by extracellular matrix (2014) (0)
- Idiotipy of monoclonal antibodies to HLA-DR antigens as a means for further definition of HLA-DR antibodies (1982) (0)
- A Predictive Mathematical Modeling Approach for the Study of Doxorubicin Treatment in Triple Negative Breast Cancer (2017) (0)
- VP30.01: Cell‐free DNA screening for 22q11.2DS by targeted method based on microarray quantitation in the average risk population: results from a single European laboratory (2020) (0)
- Variable Cell Line Pharmacokinetics Contribute to Non-Linear Treatment Response in Heterogeneous Cell Populations (2018) (0)
- The involvement of laminin_5 in podosome formation (2006) (0)
- Abstract P1-08-20: In silico analysis of a novel mathematical model integrating in vitro and in vivo imaging data reveals driving mechanisms of breast cancer response to NAT for personalized tumor forecasting (2022) (0)
- Abstract A22: A window into 3D culture: A multi-modal imaging compatible bioreactor for developing tumor growth models (2017) (0)
- Author Correction: Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data (2019) (0)
- Unified Tumor Growth Mechanisms from Multimodel Inference and Dataset Integration (2023) (0)
- Ion channel dysregulation and ferroptosis susceptibility in a heterogeneous DTP state (2022) (0)
- Biological Scales (2007) (0)
- Abstract A43: BRAF-mutated melanomas exhibit distinct metabolic programs that may determine therapeutic response (2016) (0)
- The role of MT4_MMP in renal development (2006) (0)
- Determining the mechanism of integrin-laminin binding (2006) (0)
- Keystone symposia on molecular & cellular biology announces (1992) (0)
- Extracellular Matrix in Breast Cancer Invasion (2000) (0)
- DDDR-28. EGFR AND SRC-MEDIATED ACTIVATION OF STAT3 DRIVES RESISTANCE TO MITOTIC INHIBITORS IN GLIOBLASTOMA, AND CAN BE REVERSED WITH FDA-APPROVED DRUGS (2022) (0)
- Abstract 776: Multiscale treatment response model for triple-negative breast cancer linking drug pharmacokinetics to tumor cell population dynamics (2016) (0)
- PD01-08: Heterogeneity of Lapatinib Responses in HCC1954 HER2−Overexpressing Breast Cancer Cells Revealed by Single-Cell Automated Microscopy. (2011) (0)
- The role of MT1_MMP in renal development (2006) (0)
- Quantifying Multi‐dimensional Drug Synergy along Axes of Potency and Efficacy in Anti‐Cancer Combinations (2018) (0)
- Role of Integrin-Related Tyrosine Kinases in Growth Control of Normal and Tumorigenic Human Mammary Epithelium. (1995) (0)
- Involvement of Epithelial–Mesenchymal Transition Genes in Small Cell Lung Cancer Phenotypic Plasticity (2022) (0)
- Cells Surface markers of human pancreatic cancer cells (1988) (0)
- Abstract PS13-44: Identifying relevant parameters that characterize the early response to NAT in breast cancer patients using a novel personalized mechanistic model integratingin vitroandin vivoimaging data (2021) (0)
- Abstract 3747: Identification of NSCLC biomarkers underlying quantifiable drug-induced clonal fitness (2015) (0)
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