Vivian Li
#139,698
Most Influential Person Now
Hong Kong-born cell and developmental biologist
Vivian Li's AcademicInfluence.com Rankings
Vivian Libiology Degrees
Biology
#10727
World Rank
#14080
Historical Rank
Developmental Biology
#234
World Rank
#242
Historical Rank
Cell Biology
#798
World Rank
#817
Historical Rank
Download Badge
Biology
Vivian Li's Degrees
- PhD Cell and Developmental Biology Stanford University
Why Is Vivian Li Influential?
(Suggest an Edit or Addition)According to Wikipedia, Vivian Li is a Hong Kong-born cell and developmental biologist working in cancer research at London's Francis Crick Institute. She has been researching how stem cells in the human bowel are programmed to ensure a healthy organ and what goes wrong when cancer develops. She is known for her work on the Wnt signalling pathway, discovering a new way that a molecule called Wnt is activated in bowel cancer. She won a Future Leaders in Cancer Research Prize in part for this discovery.
Vivian Li's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients (2015) (1561)
- Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling (2011) (1125)
- In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration (2013) (1123)
- Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer (2014) (860)
- Wnt Signaling through Inhibition of β-Catenin Degradation in an Intact Axin1 Complex (2012) (791)
- Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis (2013) (553)
- Gene expression patterns of human colon tops and basal crypts and BMP antagonists as intestinal stem cell niche factors (2007) (543)
- Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer (2006) (315)
- Extracellular matrix hydrogel derived from decellularized tissues enables endodermal organoid culture (2019) (291)
- Targeting Wnt signaling in colorectal cancer. A Review in the Theme: Cell Signaling: Proteins, Pathways and Mechanisms. (2015) (267)
- Mutations of PIK3CA in gastric adenocarcinoma (2005) (223)
- Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon (2016) (216)
- Diabetes Risk Gene and Wnt Effector Tcf7l2/TCF4 Controls Hepatic Response to Perinatal and Adult Metabolic Demand (2012) (202)
- Peyer's Patch M Cells Derived from Lgr5+ Stem Cells Require SpiB and Are Induced by RankL in Cultured “Miniguts” (2012) (195)
- The kinase TNIK is an essential activator of Wnt target genes (2009) (170)
- Profiling proliferative cells and their progeny in damaged murine hearts (2018) (121)
- Intestinal Stem Cell Niche: The Extracellular Matrix and Cellular Components (2017) (111)
- A brief history of organoids (2020) (104)
- The BMP Antagonist Follistatin-Like 1 Is Required for Skeletal and Lung Organogenesis (2011) (96)
- USP7 Is a Tumor-Specific WNT Activator for APC-Mutated Colorectal Cancer by Mediating β-Catenin Deubiquitination (2017) (88)
- The Leukemia-Associated Mllt10/Af10-Dot1l Are Tcf4/β-Catenin Coactivators Essential for Intestinal Homeostasis (2010) (84)
- Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy (2021) (72)
- Identifying strategies to target the metabolic flexibility of tumours (2020) (60)
- Engineering transplantable jejunal mucosal grafts using patient-derived organoids from children with intestinal failure (2020) (60)
- Cell-Type Specific Signalling Networks in Heterocellular Organoids (2020) (55)
- Frequent inactivation of axon guidance molecule RGMA in human colon cancer through genetic and epigenetic mechanisms. (2009) (42)
- NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor (2019) (41)
- Metabolic precision labeling enables selective probing of O-linked N-acetylgalactosamine glycosylation (2020) (37)
- MAP3K1 functionally interacts with Axin1 in the canonical Wnt signalling pathway (2010) (33)
- Tissue-Engineering the Intestine: The Trials before the Trials. (2019) (31)
- Wnt and Src signals converge on YAP‐TEAD to drive intestinal regeneration (2021) (31)
- SARS-CoV-2 infection and replication in human gastric organoids (2021) (28)
- Hallmarks of intestinal stem cells (2020) (27)
- Pak1 Kinase Maintains Apical Membrane Identity in Epithelia (2018) (26)
- Title Mutations of PIK 3 CA in gastric adenocarcinoma (2004) (23)
- In vitro expansion and transplantation of intestinal crypt stem cells. (2012) (21)
- Intestinal Regeneration: YAP—Tumor Suppressor and Oncoprotein? (2013) (18)
- SH3BP4 Regulates Intestinal Stem Cells and Tumorigenesis by Modulating β-Catenin Nuclear Localization (2019) (16)
- Modelling intestinal inflammation and infection using ‘mini-gut’ organoids (2020) (15)
- The Transcription Co-Repressors MTG8 and MTG16 Regulate Exit of Intestinal Stem Cells From Their Niche and Differentiation Into Enterocyte vs Secretory Lineages (2020) (15)
- SARS-CoV-2 infection and replication in human fetal and pediatric gastric organoids (2020) (10)
- Targeting Wnt signaling in colorectal cancer (2015) (10)
- Assessing the Link Between Perception and Production in Cantonese Tone Acquisition. (2019) (8)
- Single-Cell Signalling Analysis of Heterocellular Organoids (2019) (6)
- Extracellular Matrix Remodeling in Intestinal Homeostasis and Disease (2018) (6)
- Building gut from scratch — progress and update of intestinal tissue engineering (2022) (5)
- Cell-type-specific signaling networks in heterocellular organoids (2020) (5)
- Development of Phonetic Contrasts in Cantonese Tone Acquisition. (2020) (4)
- Atypical cyclin P regulates cancer cell stemness through activation of the WNT pathway (2021) (3)
- NEDD 4 and NEDD 4 L regulate Wnt signalling and intestinal stem cell priming by degrading LGR 5 receptor (2019) (3)
- The Perception of Cantonese Vowel Length Contrast by Mandarin Speakers (2020) (3)
- Identifying strategies to target the metabolic flexibility of tumours (2020) (3)
- Bioengineering human intestinal mucosal grafts using patient-derived organoids, fibroblasts and scaffolds (2022) (2)
- ZAKβ is activated by cellular compression and mediates contraction‐induced MAP kinase signaling in skeletal muscle (2022) (2)
- Yap in regeneration and symmetry breaking (2019) (1)
- OC-032 Regenerative medicine for intestinal failure: demonstrating the potential for intestinal organoids to repopulate the epithelium of the intestine (2015) (1)
- Faculty Opinions recommendation of NOTUM from Apc-mutant cells biases clonal competition to initiate cancer. (2021) (1)
- 3D-culture of intestinal stem cells using an extracellular matrix hydrogel derived from decellularised intestinal tissue (2017) (1)
- Engineering transplantable jejunal mucosal grafts using primary patient-derived organoids from children with intestinal failure (2019) (1)
- Triple Negative Breast Cancer Patients with Brain Metastasis Are Associated with More Concurrent Lung Metastases. (2009) (1)
- Faculty Opinions recommendation of RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6. (2018) (0)
- Faculty Opinions recommendation of Complete Meiosis from Embryonic Stem Cell-Derived Germ Cells In Vitro. (2016) (0)
- Faculty Opinions recommendation of TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis. (2018) (0)
- PS-292 Tissue Engineering In Oesophageal Atresia: Generation Of Decellularized Animal Scaffolds And Comparison Of Different Storage Methods (2014) (0)
- Faculty Opinions recommendation of The landscape of somatic mutation in normal colorectal epithelial cells. (2020) (0)
- 305 FRAILTY AS A PREDICTOR FOR POSTOPERATIVE OUTCOMES FOLLOWING PANCREATICODUODENECTOMY. (2021) (0)
- Faculty Opinions recommendation of SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling. (2021) (0)
- Faculty Opinions recommendation of Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal. (2017) (0)
- Faculty Opinions recommendation of Homeostatic mini-intestines through scaffold-guided organoid morphogenesis. (2020) (0)
- Faculty Opinions recommendation of Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli. (2020) (0)
- Cachd1 is a novel Frizzled- and LRP6-interacting protein required for neurons to acquire left-right asymmetric character (2022) (0)
- Faculty of 1000 evaluation for The consensus molecular subtypes of colorectal cancer. (2018) (0)
- Faculty Opinions recommendation of Self-assembly of embryonic and two extra-embryonic stem cell types into gastrulating embryo-like structures. (2018) (0)
- Stabilisation of β-Catenin-WNT signalling by USP10 in APC-truncated colorectal cancer drives cancer stemness and enables super-competitor signalling (2023) (0)
- Engineering transplantable jejunal mucosal grafts using patient-derived organoids from children with intestinal failure (2020) (0)
- Me and my telescope (2019) (0)
- PNAS Plus Significance Statements (2016) (0)
- Abstract 983: Wnt pathway activation involves inhibition of β-catenin ubiquitination within the endogenous Axin1 complex (2012) (0)
- /a-a/ AND /i-i/ AT THREE JUNCTURES IN CANTONESE (2019) (0)
- Contents (2014) (0)
- Pitching in tone and non-tone second languages: Cantonese, Mandarin and English produced by Mandarin and Cantonese speakers (2016) (0)
- Correction: The Leukemia-Associated Mllt10/Af10-Dot1l Are Tcf4/β-Catenin Coactivators Essential for Intestinal Homeostasis (2017) (0)
- Journal Pre-proof The Transcription co-Repressors and MTG16 Regulate Exit of Intestinal Stem Cells From Their Niche and Differentiation into Enterocyte vs Secretory Lineages (2020) (0)
- Abstract 5016: Retinoic acid receptor responder 3 expression suppresses colorectal cancer cell growthin vitroand is a stage-independent prognostic marker in colorectal cancer patientsin vivo (2010) (0)
- Yap in regeneration and symmetry breaking (2019) (0)
- Faculty of 1000 evaluation for Intercellular coupling of the cell cycle and circadian clock in adult stem cell culture. (2018) (0)
- Faculty Opinions recommendation of Heterotypic cell-cell communication regulates glandular stem cell multipotency. (2020) (0)
- Faculty Opinions recommendation of An organoid-based organ-repurposing approach to treat short bowel syndrome. (2021) (0)
- Mass Cytometry for Multivariate Organoid Signalling Analysis (2020) (0)
- Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target (2023) (0)
- Faculty Opinions recommendation of Self-organization and symmetry breaking in intestinal organoid development. (2019) (0)
- Pak 1 Kinase Maintains Ap ical Membrane Identity in Epithelia Graphical (2018) (0)
- Faculty Opinions recommendation of Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients. (2019) (0)
- Faculty Opinions recommendation of Developmental barcoding of whole mouse via homing CRISPR. (2019) (0)
- USP7 inactivation suppresses APC-mutant intestinal hyperproliferation and tumor development (2022) (0)
This paper list is powered by the following services:
Other Resources About Vivian Li
What Schools Are Affiliated With Vivian Li?
Vivian Li is affiliated with the following schools:
