William A. Pettinger
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William A. Pettingermedical Degrees
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#3861
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Pharmacology
#423
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#476
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William A. Pettingerphilosophy Degrees
Philosophy
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Medical Philosophy
William A. Pettinger's Degrees
- PhD Pharmacology University of California, San Francisco
- Doctorate Medicine University of California, San Francisco
Why Is William A. Pettinger Influential?
(Suggest an Edit or Addition)William A. Pettinger's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A functional basis for classification of α-adrenergic receptors (1977) (797)
- Triglyceride, high density lipoprotein, and coronary heart disease. (1993) (335)
- Cardiovascular responses to exercise as functions of absolute and relative work load. (1983) (195)
- Drug therapy. Prazosin. (1979) (178)
- "Strict" blood pressure control and progression of renal disease in hypertensive nephrosclerosis. (1995) (164)
- Renal alpha-1 and alpha-2 adrenergic receptors: biochemical and pharmacological correlations. (1981) (155)
- Minoxidil — An Alternative to Nephrectomy for Refractory Hypertension (1973) (150)
- Evidence for a Renal α‐Adrenergic Receptor Inhibiting Renin Release (1976) (136)
- Evidence for the release of bradykinin in carcinoid syndrome. (1966) (131)
- Role of muscle mass and mode of contraction in circulatory responses to exercise. (1985) (126)
- Reversible renal insufficiency due to angiotensin converting enzyme inhibitors in hypertensive nephrosclerosis. (1991) (118)
- Angiotensin II- and Angiotensin III-Induced Aldosterone Release in vivo in the Rat (1974) (117)
- Role of osmolality in blood pressure stability after dialysis and ultrafiltration. (1980) (114)
- Clonidine: a new antihypertensive drug. (1975) (109)
- Renin release, saralasin and the vasodilator-beta-blocker drug interaction in man. (1975) (102)
- Renin suppression by DOC and NaCl in the rat. (1971) (97)
- Efficacy of prazosin in the management of chronic congestive heart failure: a 6-month randomized, double-blind, placebo-controlled study. (1983) (91)
- Renal function during long-term treatment of hypertension with minoxidil: comparison of benign and malignant hypertension. (1980) (88)
- A functional basis for classification of alpha-adrenergic receptors. (1977) (86)
- Abnormal cardiovascular regulation in the mitral valve prolapse syndrome. (1983) (84)
- Altered renin release and propranolol potentiation of vasodilatory drug hypotension. (1975) (82)
- Long‐Term Improvement in Renal Function After Short‐Term Strict Blood Pressure Control in Hypertensive Nephrosclerosis (1989) (76)
- Renal alpha 2-adrenoceptors and the adenylate cyclase-cAMP system: biochemical and physiological interactions. (1987) (73)
- Altered renal alpha 2-adrenergic receptor regulation in genetically hypertensive rats. (1982) (70)
- Increased pulmonary vascular resistance with systemic hypertension. Effect of minoxidil and other antihypertensive agents. (1977) (69)
- Renal nerve stimulation causes alpha 1-adrenoceptor-mediated sodium retention but not alpha 2-adrenoceptor antagonism of vasopressin. (1985) (68)
- Dietary sodium regulation of blood pressure and renal α1- and α2- receptors in WKY and SH rats☆ (1981) (67)
- INAPPROPIATE SECRETION OF ANTIDIURETIC HORMONE DUE TO MYXEDEMA. (1965) (64)
- Alpha2-adrenoceptors and cellular cAMP levels in single nephron segments from the rat. (1985) (63)
- Pharmacology of Clonidine (1980) (60)
- Effects of long-term clonidine administration on the hemodynamic and neuroendocrine postural responses of patients with dysautonomia. (1983) (56)
- Renal Alpha‐Adrenergic Receptor Abnormality in the Spontaneously Hypertensive Rat (1982) (51)
- Alpha 2-adrenoceptor antagonism of vasopressin-induced changes in sodium excretion. (1985) (49)
- Minoxidil and the treatment of severe hypertension. (1980) (47)
- Long-term treatment of refractory hypertensive patients with minoxidil. (1978) (45)
- Effects of Prazosin and Phentolamine on Arterial Pressure, Heart Rate, and Renin Activity: Evidence in the Conscious Rat for the Functional Significance of the Presynaptic α-Receptor (1979) (42)
- Altered calcium homeostasis in Dahl hypertensive rats: physiological and biochemical studies. (1986) (42)
- Radioimmunoassay and pharmacokinetics of saralasin in the rat and hypertensive patients (1975) (42)
- Enhanced release of endothelium-derived relaxing factor in mineralocorticoid hypertension. (1992) (41)
- Anesthetics and the renin--angiotensin--aldosterone axis. (1978) (39)
- Subtype-selective alpha-1 adrenoceptor alkylation in the rat kidney and its effect on the vascular pressor response. (1992) (38)
- Regional distribution of alpha 1-adrenoceptor subtypes in rat kidney. (1991) (36)
- Renal alpha 2-adrenergic receptors multiply and mediate sodium retention after prazosin treatment. (1986) (36)
- Minoxidil--an alternative to nephrectomy for refractory hypertension. (1973) (34)
- Haemodynamic responses to static and dynamic handgrip before and after autonomic blockade. (1983) (33)
- Lactation Due to Methyldopa (1963) (33)
- Unusual alpha adrenergic receptor potency of methyldopa metabolites on melanocyte function. (1977) (32)
- Renal alpha 2-adrenergic receptors and hypertension. (1987) (32)
- Dietary Sodium and Renal α2-Adrenergic Receptors in Dahl Hypertensive Rats (1982) (32)
- Sex influence on renal alpha 2-adrenergic receptor density in the spontaneously hypertensive rat. (1994) (31)
- Segregation analysis of autosomal dominant polycystic kidney disease (1993) (30)
- Organ specificity of angiotensin II and Des-aspartyl angiotensin II in the conscious rat. (1976) (29)
- Clonidine and the vasodilating beta blocker antihypertensive drug interaction (1977) (28)
- Enhancement by Methyldopa of Tyramine Sensitivity in Man (1963) (28)
- Detection and treatment of patients with renovascular hypertension (1966) (27)
- Alpha-1 adrenoceptor selectivity of phenoxybenzamine in the rat kidney. (1984) (27)
- Renal alpha 1-adrenergic receptor response coupling in spontaneously hypertensive rats. (1988) (26)
- Studies on the mechanism of kinin formation in inflammation (1967) (26)
- Testosterone Regulation of Renal α2B-Adrenergic Receptor mRNA Levels (1995) (26)
- Comparative Effects of Prazosin and Phenoxybenzamine on Arterial Blood Pressure, Heart Rate, and Plasma Catecholamines in Essential Hypertension (1979) (26)
- Myocardial beta-adrenergic receptors in the stroke-prone spontaneously hypertensive rat. (1980) (26)
- Single-drug therapy for hypertension in men. (1993) (24)
- The Effects of Altered Sodium Balance and Adrenergic Blockade on Renin Release Induced in Rats by Angiotensin Antagonism (1976) (23)
- Alpha 2-adrenoceptors and sodium reabsorption in the isolated perfused rat kidney. (1984) (22)
- Lack of inhibition by atrial natriuretic factor on cyclic AMP levels in single nephron segments and the glomerulus. (1985) (22)
- Renin release and ketamine-induced cardiovascular stimulation in the rat. (1974) (21)
- The control of hypertension in patients undergoing regular maintenance hemodialysis. (1975) (21)
- Central and regional hemodynamic effects and neurohumoral consequences of minoxidil in severe congestive heart failure and comparison to hydralazine and nitroprusside. (1983) (21)
- The frequency of alpha 2-adrenoceptor restriction fragment length polymorphisms in normotensive and hypertensive humans. (1992) (20)
- Renal alpha 2-adrenoceptors, their locations and effects on sodium excretion. (1985) (19)
- The Influence of Circulating Catecholamines and Prostaglandins on Canine Renal Hemodynamics during Hemorrhage (1981) (19)
- Role of substance P in water homeostasis. (1979) (18)
- Endotoxin-induced kinin (bradykinin) formation: activation of Hageman factor and plasma kallikrein in human plasma. (1970) (18)
- Angiotensin antagonism and antihypertensive activity of phosphodiesterase inhibiting agents. (1973) (18)
- The dominance of adrenergic mechanisms in mediating hypotensive drug-induced renin release in the conscious rat. (1979) (17)
- Effects of substance P on renin release and renal function in anesthetized dogs. (1979) (17)
- Sodium chloride suppression of renin release in the unanesthetized rat. (1975) (17)
- Reduced contractile sensitivity and vasopressin receptor affinity in DOCA-salt hypertension. (1992) (17)
- Inhibition of renin release by α-adrenoceptor stimulation in the isolated perfused rat kidney (1987) (17)
- Vasodilating antihypertensive drug-induced aldosterone release--a study of endogenous angiotensin-mediated aldosterone release in the rat. (1975) (17)
- Association Analysis of Restriction Fragment Length Polymorphism for α2‐Adrenergic Receptor Genes in Essential Hypertension in Japan (1994) (16)
- Regulation of renal cellular cAMP levels by prostaglandins and alpha 2-adrenoceptors: microdissection studies. (1986) (16)
- Adjusted resistive index: a method to estimate rapidly renal blood flow: preliminary validation in hypertensives (1993) (15)
- Dietary sodium regulation of blood pressure and renal alpha 1- and alpha 2-receptors in WKY and SH rats. (1981) (15)
- Pharmacological evidence for a functional role of the prejunctional alpha-adrenoreceptor in noradrenergic neurotransmission in the conscious rat (1980) (15)
- Characterization of prazosin-sensitive alpha 2 B-adrenoceptors expressed by cultured rat IMCD cells. (1991) (14)
- Cosegregation of the renin gene with an increase in mean arterial blood pressure in the F2 rats of SHR-WKY cross. (1993) (14)
- Vasopressin response in collecting ducts of rats resistant to mineralocorticoid hypertension. (1991) (14)
- The Hypernoradrenergic State in Vasodilator Drug‐Treated Hypertensive Patients: Effect of Clonidine (1980) (14)
- Recent advances in the treatment of hypertension. (1977) (14)
- Failure of feedback suppression of renin release in the spontaneously hypertensive rat. (1973) (14)
- Enhanced vasopressin (V2-receptor)-induced sodium retention in mineralocorticoid hypertension. (1988) (13)
- Defective renal adenylate cyclase response to prostaglandin E2 in spontaneously hypertensive rats. (1985) (13)
- Alpha 2-adrenoceptor stimulation and cellular cAMP levels in microdissected rat glomeruli. (1986) (13)
- Minoxidil and the Treatment of Severe Hypertension (1981) (12)
- Prazosin‐Induced Alterations in Renal α‐Adrenergic Receptor Function (1987) (12)
- Pseudo renal artery stenosis (PRAS) syndrome. (1989) (11)
- Additive effect of beta-adrenergic blockers in combination with vasodilators in lowering blood pressure. (1976) (11)
- Alteration of renin release by stress and adrenergic receptor and related drugs in unanesthetized rats. (1972) (11)
- Restoration of Tyramine Pressor Responses in Reserpine-Treated Animals by Methyldopa and Its Amine Metabolites (1965) (11)
- Renal Function in Long‐Term Minoxidil‐Treated Patients (1980) (10)
- Angiotensin II- and angiotensin 3-induced aldosterone release vivo in the rat. (1974) (10)
- Endothelium, vasopressin receptors, and resistance to DOCA-salt hypertension. (1993) (9)
- QUANTIFYING METABOLIC EFFECTS OF ANTIHYPERTENSIVE AND OTHER DRUGS AT THE SYMPATHETIC NEURON LEVEL: CLINICAL AND BASIC CORRELATIONS (1971) (9)
- Dose‐Response of Clonidine on Plasma Catecholamines in the Hypernoradrenergic State Associated with Vasodilator β‐Blocker Therapy (1981) (9)
- Further studies on the hypernoradrenergic state of treated hypertensives: effect of captopril. (1983) (8)
- Enhancement of serum renin activity by exercise in the rat. (1973) (8)
- Renal α2-Adrenoceptor Overexpression in Dahl Salt-Sensitive Rats: Regulation by Dietary NaCl and Dissociation from Salt-Insensitive Hypertension (1992) (7)
- Adrenergic signal transduction in the kidney. (1989) (7)
- Hyperfiltration and conservation of renal function in hypertensive nephrosclerosis patients. (1993) (7)
- Clinical pharmacology of angiotensin antagonists. (1976) (7)
- Enhanced cAMP response to vasopressin in the CCT of DOCA-Na hypertensive rats. (1986) (7)
- Effect of antihypertensive therapy on plasma catecholamines in renal failure patients. (1981) (7)
- Dietary sodium and renal alpha 2-adrenergic receptors in Dahl hypertensive rats. (1982) (7)
- Altered Renal Alpha2‐Adrenergic Receptor Regulation in Genetically Hypertensive Rats (1982) (6)
- The generic prescribing issue. (1980) (6)
- Testosterone regulation of renal alpha 2B-adrenergic receptor mRNA levels. (1995) (6)
- Sexual Dimorphism of Renal α2-Adrenergic Receptor Regulation in Dahl Rats (1996) (6)
- Drug therapy: clonidine, a new antihypertensive drug. (1975) (6)
- Autonomic ganglionitis with severe hypertension, migraine, and episodic but fatal hypotension (1996) (6)
- Workshop Target Organ Consequences in Hypertension: Pathogenesis and Prevention Participants (1991) (6)
- Northern blot and ribonuclease protection study of alpha 2-adrenoceptor subtypes in cultured cell lines. (1992) (5)
- Does the kidney play a role in the sexual dimorphism of blood pressure in SHR? (1994) (5)
- Clonidine and prazosin effects in hypernoradrenergic vasodilator–treated and β‐blocker–treated patients (1981) (5)
- Hypertension's 3 Dilemmas and 3 Solutions: Pharmacology of the Kidney in Hypertension (2017) (5)
- Pharmacokinetics of bolus potassium injections for cardiac arrhythmias. (1973) (5)
- Plasma substance P levels in normotensive and hypertensive subjects. (1981) (5)
- Introduction: The Brook Lodge Conference on Minoxidil (1980) (4)
- Hypertension, race, and renal insufficiency. (1989) (4)
- Inhibition of renin release by alpha-adrenoceptor stimulation in the isolated perfused rat kidney. (1987) (4)
- Single and combined therapy for systemic hypertension with propranolol, hydralazine and hydrochlorothiazide: hemodynamic and neuroendocrine mechanisms of action. (1985) (4)
- α 2-Adrenoceptors: Challenges and Opportunities—Enlightenment from the Kidney (2020) (4)
- The distorted alpha 2-adrenoceptor genotype distribution in F2 populations of Dahl salt sensitive and resistant rats cross. (1993) (4)
- HYPOTENSION DURING ANGIOTENSIN BLOCKADE WITH SARALASIN (1975) (4)
- alpha-1 Adrenergic Receptors (1987) (4)
- Renal function studies in the detection of renal hypertension. (1970) (3)
- Cosegregation of the renin gene with an increase in mean arterial blood pressure in the F2 rats of SHR-WKY cross. (1993) (3)
- Diuretics potentiate the angiotensin converting-enzyme inhibitor-associated acute renal dysfunction. (1992) (3)
- Treatment of hypertension in nondiabetic renal disease. (1994) (3)
- Renal Nerve Stimulation Causes ai-Adrenoceptor-Mediated Sodium Retention but Not a 2 -Adrenoceptor Antagonism of Vasopressin (2005) (3)
- Renal α2-Adrenoceptors, Their Locations and Effects on Sodium Excretion (1985) (3)
- Sexual dimorphism of renal alpha2-adrenergic receptor regulation in Dahl rats. (1996) (3)
- DOCA-enhanced sites of vasopressin-stimulated cAMP formation in rat cortical collecting tubule. (1992) (3)
- Tonic inhibition of renal response to vasopressin by a pertussis toxin substrate. (1988) (3)
- Genetic contamination of inbred Dahl rats from Harlan Sprague Dawley. (1995) (2)
- Alpha 2-adrenoceptor regulation of parathyroid hormone function in the isolated perfused kidney. (1989) (2)
- Mapping of a Dde I RELP of the α2-Adrenoceptor Gene and the Correlation of Genotype with Blood Pressure in the F2 Rats of SHR-WKY Cross (1992) (2)
- PROPRANOLOL IN REFRACTORY HIGH-RENIN DIALYSIS (1976) (1)
- Beta-blocking therapy: Propranolol. (1974) (1)
- Allosteric Modulation of Renal α2-Adrenoceptor Binding by Sodium in Inbred Dahl Rats (1994) (1)
- Determinants of maximal exercise capacity in congestive cardiomyopathy (1982) (1)
- Pulmonary hypertension in chronic minoxidil therapy (1976) (1)
- Spontaneous hazardous chemical explosion of unopened bottles of diethyl pyrocarbonate (DEPC). (1992) (1)
- Renal arAdrenergic Receptor Response Coupling in Spontaneously Hypertensive Rats (1988) (1)
- The role of renal catecholamines in hypertension. (1985) (1)
- Plasma Kinin Formation and Human Inflammation (1968) (1)
- Multidrug regimens in moderate & severe hypertension. (1992) (1)
- Renal baro receptor vs sympathetic mechanisms controlling renin release (1977) (0)
- The Antihypertensive Effects of MAO Inhibitors (1967) (0)
- Alpha 1-adrenoceptor blockade and altered renal alpha 2-adrenoceptors: a model(?) for the study of genetically altered alpha 2-adrenoceptors in hypertensive rats. (1986) (0)
- Opportunities—Enlightenment from the Kidney (2020) (0)
- [Comparison of the effects of prazosin and phenoxybenzamine on arterial pressure, heart rate and plasma catecolamines in essential arterial hypertension]. (1980) (0)
- -90-RELATIONSHIP BETWEEN α_2-ADRENOCEPTORS (α_2-A) AND PROSTAGLANDINS IN THE RAT KIDNEY (1986) (0)
- Long-term blood pressure control preserves renal function in black and white patients with hypertension and advanced renal failure (1993) (0)
- Renal Function During Long-Term Treatment of Hypertension with Minoxidil (2020) (0)
- Jim Murray Film: William Pettinger interview transcript (1976) (0)
- Angiotensin antagonists as diagnostic and pharmacologic tools. (1976) (0)
- RENIN RELEASE IN THE SH RAT A modification of the procedures of Williams (2003) (0)
- Plasma norepinephrine a renal risk factor in severely hypertensive patients treated with minoxidil (1979) (0)
- Renal alpha 2-adrenoceptors as potential targets for converting enzyme inhibitors. (1987) (0)
- The Expression of α2B-Adrenoceptor mRNA in Sprague-Dawley Rat Kidney (1993) (0)
- Drug interactions with saralasin. (1979) (0)
- A Comparison of the Neural and Hormonal Aspects of the Sympathico-Adrenal Medullary System (1957) (0)
- Letter: Hypotension during angiotensin blockade with saralasin. (1975) (0)
- Minoxidil and Cardiac Enlargement-Reply (1978) (0)
- Comparison of pharmacologic and biochemical characteristics of renal alpha receptors (1979) (0)
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