William Clarke Little
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William Clarke Little's Degrees
- PhD Biomedical Engineering Stanford University
- Doctorate Medicine Stanford University
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(Suggest an Edit or Addition)William Clarke Little's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Can coronary angiography predict the site of a subsequent myocardial infarction in patients with mild-to-moderate coronary artery disease? (1988) (1538)
- Pathophysiological characterization of isolated diastolic heart failure in comparison to systolic heart failure. (2002) (870)
- The pathogenesis of acute pulmonary edema associated with hypertension. (2001) (594)
- Development and validation of a risk score for predicting death in Chagas' heart disease. (2006) (546)
- Force-Induced Unfolding of Fibronectin in the Extracellular Matrix of Living Cells (2007) (419)
- Cardiac cycle-dependent changes in aortic area and distensibility are reduced in older patients with isolated diastolic heart failure and correlate with exercise intolerance. (2001) (379)
- Exercise Training in Older Patients With Heart Failure and Preserved Ejection Fraction: A Randomized, Controlled, Single-Blind Trial (2010) (362)
- Utility of fast cine magnetic resonance imaging and display for the detection of myocardial ischemia in patients not well suited for second harmonic stress echocardiography. (1999) (337)
- The Left Ventricular dP/dtmax‐End‐Diastolic Volume Relation in Closed‐Chest Dogs (1985) (327)
- Determination of left ventricular chamber stiffness from the time for deceleration of early left ventricular filling. (1995) (323)
- Diastolic heart failure can be diagnosed by comprehensive two-dimensional and Doppler echocardiography. (2006) (319)
- Low to moderate dose anthracycline-based chemotherapy is associated with early noninvasive imaging evidence of subclinical cardiovascular disease. (2013) (313)
- Statin Therapy May Be Associated With Lower Mortality in Patients With Diastolic Heart Failure: A Preliminary Report (2005) (310)
- Mechanism of altered patterns of left ventricular filling during the development of congestive heart failure. (1994) (310)
- Mode of Death in Patients With Heart Failure and a Preserved Ejection Fraction: Results From the Irbesartan in Heart Failure With Preserved Ejection Fraction Study (I-Preserve) Trial (2010) (309)
- The effect of alagebrium chloride (ALT-711), a novel glucose cross-link breaker, in the treatment of elderly patients with diastolic heart failure. (2005) (309)
- Thrombogenic factors and recurrent coronary events. (1999) (301)
- The cardiovascular effects of erythropoietin. (2003) (288)
- Losartan improves exercise tolerance in patients with diastolic dysfunction and a hypertensive response to exercise. (1999) (247)
- Chagas' Heart Disease (2000) (243)
- Fibronectin forms the most extensible biological fibers displaying switchable force-exposed cryptic binding sites (2009) (235)
- Comparison of measures of left ventricular contractile performance derived from pressure-volume loops in conscious dogs. (1989) (221)
- Clinical evaluation of left ventricular diastolic performance. (1990) (218)
- Effect of alteration of left ventricular activation sequence on the left ventricular end-systolic pressure-volume relation in closed-chest dogs. (1985) (215)
- Mechanism of augmented rate of left ventricular filling during exercise. (1992) (208)
- Evaluation of Left Ventricular Contractile Performance Utilizing End‐Systolic Pressure‐Volume Relationships in Conscious Dogs (1984) (204)
- Baroreflex Activation Therapy for the Treatment of Heart Failure With a Reduced Ejection Fraction. (2015) (199)
- Diastolic mitral annular velocity during the development of heart failure. (2003) (183)
- Vascular closure devices in patients treated with anticoagulation and IIb/IIIa receptor inhibitors during percutaneous revascularization. (2002) (173)
- Mechanism of abnormal interventricular septal motion during delayed left ventricular activation. (1982) (170)
- Trends in vascular complications after diagnostic cardiac catheterization and percutaneous coronary intervention via the femoral artery, 1998 to 2007. (2008) (158)
- Echocardiographic Evaluation of Diastolic Function Can Be Used to Guide Clinical Care (2009) (156)
- Response of the left ventricular end-systolic pressure-volume relation in conscious dogs to a wide range of contractile states. (1988) (153)
- Simultaneous conductance catheter and dimension assessment of left ventricle volume in the intact animal. (1990) (152)
- Influence of Heart Rate on Left Ventricular Performance in Conscious Dogs (1987) (139)
- A Randomized Double-Blind Trial of Enalapril in Older Patients With Heart Failure and Preserved Ejection Fraction: Effects on Exercise Tolerance and Arterial Distensibility (2010) (133)
- Effect of loading conditions, contractile state, and heart rate on early diastolic left ventricular filling in conscious dogs. (1990) (132)
- Aortic stiffness increases upon receipt of anthracycline chemotherapy. (2010) (129)
- Contribution of left ventricular diastolic dysfunction to heart failure regardless of ejection fraction. (2005) (128)
- Effect of heart failure on the mechanism of exercise-induced augmentation of mitral valve flow. (1993) (128)
- Allopurinol Enhances the Contractile Response to Dobutamine and Exercise in Dogs With Pacing-Induced Heart Failure (2001) (127)
- The cardiac cycle and the physiologic basis of left ventricular contraction, ejection, relaxation, and filling. (2008) (121)
- Effect of Right Ventricular Pressure on the End‐ Diastolic Left Ventricular Pressure*dash;Volume Relationship before and after Chronic Right Ventricular Pressure Overload in Dogs without Pericardia (1984) (116)
- "Off-label" stent therapy 2-year comparison of drug-eluting versus bare-metal stents. (2008) (110)
- Assay to mechanically tune and optically probe fibrillar fibronectin conformations from fully relaxed to breakage. (2008) (110)
- The effect of vasoactive agents on the left ventricular end-systolic pressure-volume relation in closed-chest dogs. (1986) (107)
- Flash pulmonary edema: association with hypertension and reoccurrence despite coronary revascularization. (2000) (107)
- Relation of anemia to diastolic heart failure and the effect on outcome. (2004) (104)
- Vortices Formed on the Mitral Valve Tips Aid Normal Left Ventricular Filling (2011) (102)
- Altered ventricular and myocyte response to angiotensin II in pacing-induced heart failure. (1996) (101)
- Diastolic dysfunction beyond distensibility: adverse effects of ventricular dilatation. (2005) (96)
- Left ventricular-arterial coupling in conscious dogs. (1991) (95)
- Simultaneous determination of left ventricular end-systolic pressure-volume and pressure-dimension relationships in closed-chest dogs. (1985) (94)
- Angiographic assessment of the culprit coronary artery lesion before acute myocardial infarction. (1990) (92)
- Diastolic Dysfunction as a Cause of Exercise Intolerance (2000) (89)
- Chronic baroreflex activation: a potential therapeutic approach to heart failure with preserved ejection fraction. (2011) (86)
- Endogenous beta3-adrenoreceptor activation contributes to left ventricular and cardiomyocyte dysfunction in heart failure. (2004) (83)
- Mechanism of altered pattern of left ventricular filling with aging in subjects without cardiac disease. (1989) (83)
- Angiotensin II Type 1 Receptor Blockade Prevents Alcoholic Cardiomyopathy (2006) (82)
- Circ Heart Fail (2010) (81)
- Qualitative and quantitative contrasts in the mechanisms of lumen enlargement by coronary balloon angioplasty and directional coronary atherectomy. (1994) (81)
- Optimal risk factor management in the patient after coronary revascularization. A statement for healthcare professionals from an American Heart Association Writing Group. (1994) (79)
- Contribution of systolic and diastolic abnormalities to heart failure with a normal and a reduced ejection fraction. (2007) (78)
- Baroreflex activation therapy for the treatment of heart failure with a reduced ejection fraction: safety and efficacy in patients with and without cardiac resynchronization therapy (2015) (78)
- Usefulness of an elevated B-type natriuretic peptide in predicting survival in patients with aortic stenosis treated without surgery. (2005) (78)
- Fatal massive hepatic necrosis following acetaminophen overdose. (1976) (75)
- Randomized, double-blind, placebo-controlled study of sitaxsentan to improve impaired exercise tolerance in patients with heart failure and a preserved ejection fraction. (2014) (74)
- Mechanism of reduced cardiac output during positive end-expiratory pressure in the dog. (1989) (72)
- The underlying coronary lesion in myocardial infarction: Implications f coronary angiography (1991) (72)
- Levosimendan improves LV systolic and diastolic performance at rest and during exercise after heart failure. (2005) (71)
- Functional effects of endogenous bradykinin in congestive heart failure. (1998) (71)
- Effect of regional ischemia on the left ventricular end-systolic pressure-volume relation in chronically instrumented dogs. (1985) (70)
- Vascular complications with newer generations of angioseal vascular closure devices. (2006) (70)
- Effect of alteration in loading conditions on both normal and abnormal patterns of left ventricular filling in healthy individuals. (1990) (70)
- Restraining effect of intact pericardium during acute volume loading. (1992) (68)
- Propensity score analysis of vascular complications after diagnostic cardiac catheterization and percutaneous coronary intervention 1998–2003 (2006) (68)
- Assessment of left ventricular diastolic function and recognition of diastolic heart failure. (2007) (68)
- Pericardial disease. (2006) (67)
- Crosslinking of cell-derived 3D scaffolds up-regulates the stretching and unfolding of new extracellular matrix assembled by reseeded cells. (2009) (65)
- Association of C-reactive protein and serum amyloid A with recurrent coronary events in stable patients after healing of acute myocardial infarction. (2002) (62)
- Subendocardial ischemic myocardial lesions associated with severe coronary atherosclerosis. (1980) (61)
- Altered inotropic response of endothelin-1 in cardiomyocytes from rats with isoproterenol-induced cardiomyopathy. (1998) (59)
- Estimates of left-ventricular volumes by equilibrium radionuclide angiography: importance of attenuation correction. (1984) (59)
- Effect of exercise on left ventricular-arterial coupling assessed in the pressure-volume plane. (1993) (59)
- Therapy for diastolic heart failure. (2005) (58)
- Effect of Candesartan and Verapamil on Exercise Tolerance in Diastolic Dysfunction (2004) (56)
- Accurate estimates of absolute left ventricular volumes from equilibrium radionuclide angiographic count data using a simple geometric attenuation correction. (1984) (56)
- Evaluation of left ventricular diastolic function from the pattern of left ventricular filling (1998) (54)
- Feasibility to detect severe coronary artery stenoses with upright treadmill exercise magnetic resonance imaging. (2003) (54)
- Loss of adrenergic augmentation of diastolic intra-LV pressure difference in patients with diastolic dysfunction: evaluation by color M-mode echocardiography. (2012) (52)
- Altered effect of the Valsalva maneuver on left ventricular volume in patients with cardiomyopathy. (1985) (52)
- Evaluation of LV diastolic function from color M-mode echocardiography. (2011) (51)
- Right ventricular contractile protein function in rats with left ventricular myocardial infarction. (1996) (50)
- Effect of losartan and hydrochlorothiazide on exercise tolerance in exertional hypertension and left ventricular diastolic dysfunction. (2006) (50)
- Enhanced load dependence of relaxation in heart failure. Clinical implications. (1992) (49)
- Restrictive Left Ventricular Filling Pattern Does Not Result From Increased Left Atrial Pressure Alone (2006) (49)
- Mechanism of anterior ST segment depression during acute inferior myocardial infarction. Observations during coronary thrombolysis. (1984) (49)
- Inotropic effects of ejection are myocardial properties. (1994) (48)
- Comparison of effects of dobutamine and ouabain on left ventricular contraction and relaxation in closed-chest dogs. (1987) (47)
- Description of LV pressure-volume relations by time-varying elastance and source resistance. (1987) (46)
- Evolving focus on diastolic dysfunction in patients with coronary artery disease (2010) (46)
- The effects of intracoronary adenosine on preconditioning during coronary angioplasty (1995) (46)
- Congestive heart failure: systolic and diastolic function. (1993) (45)
- Stretched Extracellular Matrix Proteins Turn Fouling and Are Functionally Rescued by the Chaperones Albumin and Casein (2009) (45)
- Can left ventricular diastolic stiffness be measured noninvasively? (2002) (45)
- Stress CMR reduces revascularization, hospital readmission, and recurrent cardiac testing in intermediate-risk patients with acute chest pain. (2013) (44)
- The role of ANG II and endothelin-1 in exercise-induced diastolic dysfunction in heart failure. (2001) (44)
- Endogenous endothelin-1 depresses left ventricular systolic and diastolic performance in congestive heart failure. (1999) (44)
- The cardiac effects of pimobendan (but not amrinone) are preserved at rest and during exercise in conscious dogs with pacing-induced heart failure. (1997) (44)
- Left ventricular vortex formation is unaffected by diastolic impairment. (2012) (43)
- Restick following initial Angioseal use (2003) (43)
- Incidence of coronary stent thrombosis based on academic research consortium definitions. (2008) (40)
- American College of Cardiology training statement on recommendations for the structure of an optimal adult interventional cardiology training program: a report of the American College of Cardiology task force on clinical expert consensus documents. (1999) (39)
- Early mitral deceleration and left atrial stiffness. (2004) (38)
- Left ventricle diastolic dysfunction and prognosis. (2012) (38)
- Relation Between Left Ventricular Oxygen Consumption and Pressure‐Volume Area in Conscious Dogs (1994) (37)
- HFpEF: cardiovascular abnormalities not just comorbidities. (2012) (37)
- Alterations in left ventricular compliance due to changes in right ventricular volume, pressure and compliance. (1988) (37)
- Invasive evaluation of left ventricular diastolic performance. (1990) (37)
- Late outcomes of drug‐eluting versus bare metal stents in saphenous vein grafts: Propensity score analysis (2008) (37)
- Diastolic mitral regurgitation in acute but not chronic aortic regurgitation: implications regarding the mechanism of mitral closure. (1989) (36)
- Curvilinearity of LV end-systolic pressure-volume and dP/dtmax-end-diastolic volume relations. (1993) (35)
- Comparison of drug-eluting versus bare metal stents on later frequency of acute myocardial infarction and death. (2007) (35)
- Wave-intensity analysis: a new approach to left ventricular filling dynamics (2008) (33)
- Thrombolytic therapy of acute myocardial infarction. (1983) (33)
- Effect of Exercise on Left Ventricular Mechanical Efficiency in Conscious Dogs (1994) (33)
- Tachycardia exacerbates abnormal left ventricular–arterial coupling in heart failure (2003) (32)
- Effects of regional ischemia and ventricular pacing on LV dP/dtmax-end-diastolic volume relation. (1987) (31)
- Cost-Effectiveness of Drug-Eluting Stents Versus Bare Metal Stents in Clinical Practice (2011) (31)
- Potential precipitating factors of the onset of myocardial infarction. (1992) (30)
- Vascular complications in women after catheterization and percutaneous coronary intervention 1998-2005. (2007) (30)
- Automated contrast injection in contemporary practice during cardiac catheterization and PCI: effects on contrast-induced nephropathy. (2006) (30)
- Acute heart failure with preserved systolic function (2008) (30)
- Left ventricular-arterial coupling. (2009) (30)
- Heart failure: what does ejection fraction have to do with it? (2013) (30)
- Cardiac resynchronization therapy in chronic heart failure with moderately reduced left ventricular ejection fraction: Lessons from the Multicenter InSync Randomized Clinical Evaluation MIRACLE EF study. (2016) (30)
- Effect of Length and Diameter of Drug-Eluting Stents Versus Bare-Metal Stents on Late Outcomes (2009) (29)
- Transitioning to the radial artery as the preferred access site for cardiac catheterization: An academic medical center experience (2012) (28)
- A phase II, double-blind, randomized, placebo-controlled, dose comparative study of the efficacy, tolerability, and safety of MCC-135 in subjects with chronic heart failure, NYHA class II/III (MCC-135-GO1 study): rationale and design. (2004) (28)
- Hypertensive pulmonary oedema is due to diastolic dysfunction. (2001) (27)
- Angiographic evidence of hemorrhagic myocardial infarction after intracoronary thrombolysis with streptokinase. (1983) (26)
- Left ventricular geometry during intermittent positive pressure ventilation in dogs (1987) (25)
- Effects of atrial natriuretic peptide on left ventricular performance in conscious dogs before and after pacing-induced heart failure. (1999) (25)
- Propensity score analysis of vascular complications after diagnostic cardiac catheterization and percutaneous coronary intervention using thrombin hemostatic patch-facilitated manual compression. (2007) (25)
- External pressure of undisturbed left ventricle. (1990) (25)
- Delayed Time to Peak Velocity Is Useful for Detecting Severe Aortic Stenosis (2016) (25)
- Cardiac preload, afterload, and heart failure. (1982) (24)
- Myocardial Infarction in a Patient Who Smoked while Wearing a Nicotine Patch (1994) (23)
- Direct assessment of right ventricular transmural pressure. (1987) (23)
- Cost effectiveness of radial access for diagnostic cardiac catheterization and coronary intervention (2013) (23)
- Clotted hemopericardium with the hemodynamic characteristics of constrictive pericarditis. (1980) (23)
- Acute effects of mildly intoxicating levels of alcohol on left ventricular function in conscious dogs. (1990) (23)
- Comparison of effects of dihydropyridine calcium antagonists on left ventricular systolic and diastolic performance. (1994) (23)
- Prognostic implications of vascular complications following PCI (2009) (22)
- Altered spatial distribution of the diastolic left ventricular pressure difference in heart failure. (2015) (22)
- ULFS‐49 Causes Bradycardia Without Decreasing Right Ventricular Systolic and Diastolic Performance (1991) (22)
- Should Patients With Heart Disease Exercise in the Morning or Afternoon (1993) (22)
- Baroreflex activation therapy for the treatment of heart failure with reduced ejection fraction in patients with and without coronary artery disease. (2018) (21)
- Vortex Formation Time is Not an Index of Ventricular Function (2015) (20)
- Effect of vasopressin on left ventricular performance. (1993) (20)
- Impaired left ventricular stroke volume reserve during clinical dobutamine stress predicts future episodes of pulmonary edema. (2011) (20)
- Cineangiography in the diagnosis of aortic dissection. (1981) (20)
- 3-year comparison of drug-eluting versus bare-metal stents. (2009) (20)
- Effects of felodipine on left ventricular systolic and diastolic performance in congestive heart failure. (1994) (19)
- Cause of acute myocardial infarction late after successful coronary artery bypass grafting. (1990) (19)
- Up-regulation and functional effect of cardiac β3-adrenoreceptors in alcoholic monkeys. (2010) (19)
- Contribution of right-sided heart enlargement to cardiomegaly on chest roentgenogram in diastolic and systolic heart failure. (2007) (19)
- Surgical Experience and Long-term Results of Baroreflex Activation Therapy for Heart Failure With Reduced Ejection Fraction. (2016) (19)
- Coronary angiography: more than meets the eye. (1993) (19)
- Heart failure with a normal left ventricular ejection fraction: diastolic heart failure. (2008) (18)
- Observational studies of statins in heart failure with preserved systolic function. (2008) (18)
- Effects of autonomic modulation: more than just blood pressure. (2012) (18)
- Diagnosis of diastolic heart failure (2007) (18)
- Role of plaque size and degree of stenosis in acute myocardial infarction. (1996) (17)
- Should patients with heart disease exercise in the morning or afternoon? (1993) (17)
- Left ventricular spherical dilation and regional contractile dysfunction in dogs with heart failure. (1997) (16)
- Reduction of left ventricular mass in normal rats by captopril. (1987) (16)
- A simple method for measurement of left ventricular septal-lateral dimension. (1988) (16)
- Exercise intolerance in heart failure with preserved ejection fraction: what does the heart have to do with it? (2015) (15)
- Culprit vessel PCI versus traditional cath and PCI for STEMI. (2008) (15)
- Orally Available Levosimendan Dose-Related Positive Inotropic and Lusitropic Effect in Conscious Chronically Instrumented Normal and Heart Failure Dogs (2008) (15)
- Assessment of Left Ventricular Diastolic Function Using 4-Dimensional Phase-Contrast Cardiac Magnetic Resonance (2011) (15)
- Comparison of in situ and in vitro studies of pericardial pressure-volume relation in dogs. (1986) (14)
- Pulmonary hypertension in heart failure with preserved left ventricular ejection fraction: diagnosis and management (2012) (14)
- Vascular selective calcium entry blockers in the treatment of cardiovascular disorders: Focus on felodipine (1995) (14)
- Relation of cardiac prognosis to segment location with apical left ventricular ischemia. (2003) (14)
- Sex and cardiovascular risk: are women advantaged or men disadvantaged? (2012) (14)
- Effect of adenosine on contractile state and oxygen consumption in isolated rat hearts. (1994) (13)
- A microcomputer based automated, quantitative coronary angiographic analysis system (2006) (13)
- Volume conductance catheter. (1990) (13)
- Comparison of the cardiovascular effects of intravenous and intraaortic protamine in the conscious and anesthetized dog. (1986) (13)
- β3-Adrenergic receptor antagonist improves exercise performance in pacing-induced heart failure. (2013) (12)
- Peripartum cardiomyopathy presenting as diastolic heart failure. (2008) (12)
- A safe, rapid method of transfemoral retrograde left ventricular catheterization in valvular aortic stenosis. (1981) (12)
- Effect of the transmural extent of myocardial scar on left ventricular systolic wall thickening during intravenous dobutamine administration. (2005) (11)
- Characteristics of single isovolumic left-ventricular pressure waves of dog hearts in situ (2005) (11)
- Hypertension, heart failure, and ejection fraction. (2008) (10)
- Effect of Cough on Coronary Perfusion Pressure: Does Coughing Help Clear the Coronary Arteries of Angiographic Contrast Medium? (1982) (10)
- Preprocedural white blood cell count and major adverse cardiac events late after percutaneous coronary intervention in saphenous vein grafts. (2005) (10)
- Reversal of dyskinesis by increased end diastolic segment length in ischaemic-reperfused myocardium. (1989) (9)
- Mechanism of decreased sensitivity of dobutamine associated left ventricular wall motion analyses for appreciating inducible ischemia in older adults (2015) (9)
- Effect of felodipine on left ventricular performance in conscious dogs: assessment by left ventricular pressure-volume analysis. (1991) (9)
- Zebrafish with antisense-knockdown of cardiac troponin C as a model of hereditary dilated cardiomyopathy. (2009) (9)
- Anatomic landmarks for use when measuring intracardiac pressure with fluid-filled catheters. (2000) (9)
- Modulation of Diastolic Dysfunction in the Intact Heart (1994) (9)
- Elevated left ventricular filling pressure after maximal exercise predicts increased plasma B-type natriuretic peptide levels in patients with impaired relaxation pattern of diastolic filling. (2007) (9)
- Levosimendan restores the positive force-frequency relation in heart failure. (2011) (8)
- Mechanism of physiologic and pathologic S3 gallop sounds. (1992) (8)
- Alteration of autonomic influence on left ventricular contractility by epicardial superfusion with hexamethonium and procaine. (1994) (8)
- Delay of left ventricular longitudinal expansion with diastolic dysfunction: impact on load dependence of e′ and longitudinal strain rate (2014) (8)
- Left atrial emptying reserve: a mirror of LV diastolic function that predicts prognosis? (2011) (7)
- Restenosis of a sirolimus drug‐eluting stent: Aorto‐ostial involvement of the proximal right coronary artery (2006) (7)
- Left atrial role in left ventricular filling at rest during exercise and during the development of heart failure (2000) (7)
- Coronary angiography before myocardial infarction: can the culprit site be prospectively recognized? (1998) (7)
- Role of Diastolic Function in Preserved Exercise Capacity in Patients with Reduced Ejection Fractions. (2015) (7)
- Angiographic progression to total coronary occlusion in hyperlipidemic patients after acute myocardial infarction. (1991) (6)
- Aging reduces left atrial performance during adrenergic stress in middle aged and older patients. (2012) (6)
- The shadows leave a doubt--the angiographic recognition of vulnerable coronary artery plaques. (1999) (6)
- Cause of acute myocardial infarction after successful coronary angioplasty. (1991) (6)
- Calculating Intraventricular Pressure Difference Using a Multi-Beat Spatiotemporal Reconstruction of Color M-Mode Echocardiography (2014) (6)
- Current treatment and future directions in heart failure. (2002) (5)
- Left ventricular ejection activation in the in situ heart. (1991) (5)
- Vascular Versus Myocardial Effects of Calcium Antagonists (2012) (5)
- Frequency of large V waves in the pulmonary artery wedge pressure in ventricular septal defect of acquired (during acute myocardial infarction) or congenital origin. (1987) (5)
- Diastolic Versus Systolic Heart Failure (2008) (5)
- Abstract 3361: Progressive Left Ventricle, Myocyte Dysfunction, and Heart Failure in the Lethality of Anthrax Toxin in Conscious Dogs (2007) (5)
- Target lesion revascularization after bare-metal or drug-eluting stents: clinical presentations and outcomes. (2010) (5)
- Statins beneficial for heart failure with preserved ejection fraction but not heart failure with reduced ejection fraction? (2015) (5)
- Biventricular hypoplasia with myocardial fiber hypertrophy and disarray. (1980) (5)
- A Phase 2 Randomized, Double-Blind, Placebo-Controlled Exploratory Efficacy Study of Sitaxsentan Sodium to Improve Impaired Exercise Tolerance in Subjects with Diastolic Heart Failure (2009) (4)
- Coronary collaterals in acute myocardial infarction without underlying coronary stenosis. (1990) (4)
- Mechanism of PTCA dilatation in coronary vessels: Intravascular ultrasound assessment (1991) (4)
- C-Type Natriuretic Peptide Improves Left Ventricular Functional Performance at Rest and Restores Normal Exercise Responses after Heart Failure (2016) (4)
- Defining differences in community and trial CHF patients (1999) (4)
- Late outcomes after intervention of vein grafts in diabetics with abciximab use. (2006) (3)
- Myocardial infarction following successful coronary angioplasty is not due to incomplete revascularization (1991) (3)
- Is time running out on streptokinase? (1998) (3)
- Is a higher blood pressure better in heart failure? (2008) (3)
- Presence and Implication of Temporal Nonuniformity of Early Diastolic Left Ventricular Wall Expansion in Patients With Heart Failure. (2016) (3)
- Coupling of the left ventricular and arterial system (1994) (3)
- Effect of acute cardiac tamponade on left ventricular pressure-volume relations in anaesthetised dogs. (1990) (3)
- ACUTE CORONARY SYNDROMES IN PATIENTS WITH HEART FAILURE WITH PRESERVED EJECTION FRACTION: A HARBINGER OF DEATH? (2010) (2)
- Is echocardiographic evaluation of diastolic function useful in determining clinical care? Echocardiographic Evaluation of Diastolic Function Can Be Used to Guide Clinical Care C ONTROVERSIES IN C ARDIOVASCULAR M EDICINE (2009) (2)
- Improved Ventricular-Arterial Elastance Following Chronic Treatment Using the Rheos® System Implantable Device in Resistant Hypertension (2010) (2)
- Abstract 12986: Is Beta3-Adrenoceptor (AR) a Target for Heart Failure Therapy? Evidence From Beta3-AR Knockout Mice (2011) (2)
- Comments on Defining the Contribution of Diastolic Vortex Ring to Left Ventricular Filling. (2015) (1)
- BLEEDING AVOIDANCE STRATEGY: TRANSITION FROM FEMORAL TO RADIAL ARTERY AS THE PREFERRED ACCESS FOR CARDIAC PROCEDURES. THE WAKE FOREST ACADEMIC MEDICAL CENTER EXPERIENCE (2011) (1)
- Safety of New Device-Based Approach for Treating Diastolic Heart Failure (2007) (1)
- Coughs cause systemic blood flow (1985) (1)
- Effect of alterations of the left ventricular activation sequence on left ventricular performance (1987) (1)
- Moving beyond angiotensin II to also target aldosterone? (2009) (1)
- LV Diastolic Dysfunction and Prognosis (2012) (1)
- Abstract 5248: Direct Cardiac Effect and Cellular Mechanism of Angiotensin-(1-7) in Heart Failure (2008) (1)
- Chapter 6 – General Principles, Clinical Definition, and Epidemiology (2008) (1)
- Myocardial infarction without preceding angina produces a larger infarct (1990) (1)
- Last word on point: Counterpoint: Left ventricular volume during diastasis is not the physiological in vivo equilibrium volume and is not related to diastolic suction. (2010) (1)
- Abstract 702: Diastolic Intraventricular Pressure Gradients Assessed by Color M-Mode Echocardiography (2008) (1)
- GENDER DIFFERENCES IN VASCULAR COMPLICATIONS ASSOCIATED WITH TRANSFEMORAL AND TRANSRADIAL CARDIAC CATHETERIZATION AND PCI: A SINGLE-CENTER EXPERIENCE (2013) (1)
- Heart Failure Mode of Death in Patients With Heart Failure and a Preserved Ejection Fraction (2010) (1)
- Electropharmacology of Potassium Canrenoate 1 (1974) (1)
- PCI with and without abciximab after upstream eptifibatide use: outcomes in high-risk patients. (2006) (1)
- Abstract 2945: Normalization of Beta Adrenergic Receptor Signaling Improves Left Ventricular Myocyte Function with Urotensin II Receptor Blockade in Murine Heart Failure (2008) (1)
- Barore fl ex Activation Therapy for the Treatment of Heart Failure With a Reduced Ejection Fraction (2015) (1)
- 1029-181 Enhanced cardiac beta3-adrenergic functional response in alcoholic monkeys (2004) (1)
- Effects of Atrial Natriuretic Peptide on Left Ventricular Performance in Conscious Dogs Before and After Pacing-Induced Heart Failure 1 (1999) (1)
- Improved Left Ventricular End-Systolic Myocardial Wall Stress Following Chronic Baroreflex Activation With the Rheos® System in Resistant Hypertension (2010) (1)
- Effect of mildly intoxicating levels of alcohol on left ventricular function in conscious dogs (1989) (1)
- Evaluation of the load dependence of left ventricular time varying elastance in closed chest dogs (1986) (1)
- Evaluation of diastolic function (2001) (1)
- Coronary artery spasm: An isolated phenomenon or one manifestation of a more diffuse vascular hyperreactivity? (1981) (1)
- Vortices Formed on the Mitral Valve Tips Aid Normal Left Ventricular Filling (2013) (0)
- Effects of coughing following coronary artery contrast injections. (1983) (0)
- Abstract 12583: C-Type Natriuretic Peptide Improves Left Ventricular Systolic and Diastolic Functional Performance at Rest and During Exercise After Heart Failure (2014) (0)
- Robust clinical cardiac Echo Particle Image Velocimetry (EchoPIV) (2013) (0)
- Optimal RiskFactor Management inthePatient After Coronary Revascularizatio n A Statement forHealthcare Professionals FromanAmerican HeartAssociation Writing Group (1994) (0)
- Abstract 4871: Vasopressin V1 Receptor Improves Left Ventricular Systolic and Diastolic Performance at Rest and During Exercise after Heart Failure (2008) (0)
- Abstract 172: Electrophysiological Effects of Endothelin-1: Altered Inotropic Response of Left Ventricle in Heart Failure (2007) (0)
- Effect ofCoughon Coronary Perfusion Pressure: DoesCoughing HelpClear theCoronary Arteries ofAngiographic Contrast Medium? (1982) (0)
- Abstract 087: Reversal of Aging-Induced Contrast Changes of Cardiac SERCA 2a and Inducible Nitric Oxide Synthase in Mice Deficient in Beta3-Adrenoreceptor: Insights into the Molecular Mechanism of Cardiac Aging (2013) (0)
- Abstract 9254: Downregulation of SR Ca2+-ATPase as a Contributing Cause of Impaired Cardiomyocyte Basal and Beta-Adrenergic Regulation of [Ca2+]i with Myocyte Dysfunction in Monkeys with Chronic Heavy Alcohol Consumption (2011) (0)
- Should patients with coronary artery disease exercise in the morning or afternoon (1991) (0)
- Left Ventricular Vortex Ring Dynamics and Their Association to Early Diastolic Filling (2011) (0)
- Cardiac beta3-Adrenergic Receptor: A New Target for the Treatment of Exercise Intolerance in Heart Failure (2008) (0)
- Correlation of Left Ventricle Hydrodynamic Parameters with Diastolic Dysfunction (2008) (0)
- Effect of coronary occlusion on left ventricular elastance and source resistance (1989) (0)
- EFFECT OF CARDIAC TAMPONADE ON LEFT VENTRICULAR CONTRACTILITY (1988) (0)
- Differential protein binding to mechanically tuned and optically probed fibrillar fibronectin conformations (2007) (0)
- Diastolic Dysfunction Heart Failure (2008) (0)
- AGING IMPAIRS DOBUTAMINE AUGMENTATION OF EARLY DIASTOLIC INTRAVENTRICULAR PRESSURE GRADIENT (2011) (0)
- Abstract 2239: Is Heightened Vascular Stiffness A Predictor Of Future Acute Pulmonary Edema (2008) (0)
- Impaired Dobutamine Augmentation of Early Diastolic Suction in Diastolic Dysfunction (2011) (0)
- Chapter-38 Constrictive Pericarditis (2015) (0)
- Abstract 13008: Reversal of Aging-Induced Upregulation of Cardiac Inducible Nitric Oxide Synthase and Beta-Adrenergic Desensitization in Mice Lacking the Beta3-Adrenoreceptor (2010) (0)
- A Novel Break Point Parameter as a Diagnostic Tool for Left Ventricular Diastolic Dysfunction (2008) (0)
- Abstract 1876: Functional Effect of Chronic Urotensin II Receptor Antagonist on L-Type Ca2+ Current in Mouse Model of Progressive Heart Failure (2008) (0)
- Serial angiographic studies of culprit lesions before MI. (2015) (0)
- Abstract 1995: Upregulation of Cardiac SERCA 2a by Chronic {beta}3-Adrenergic Receptor (AR) Deficiency: A Key Molecular Mechanism of the Protective Effect of {beta}3-AR Deficiency on Myocardial Aging (2009) (0)
- H-01045-2003.R1 Endogenous β3-Adrenoreceptor Activation Contributes to Left Ventricular and Cardiomyocyte Dysfunction in Heart Failure Running Head: β3-Adrenoreceptor and CHF Progression (2004) (0)
- 842-1 Anemia in diastolic heart failure is frequent and associated with worse outcome (2004) (0)
- Abstract 13311: Relation of Early Diastolic Mitral Annular Velocity, Mitral Flow Velocity, and Left Ventricular Strain Rate on Intraventricular Pressure Difference (2013) (0)
- Estimation of Left Ventricular Wall Stiffness by Analysis of Late Diastolic Pressure Components (2011) (0)
- Diastolic Function at Rest Determines the Prognosis of Myocardial Infarction (2012) (0)
- 心房性利尿ペプチド(ANP)の術後回復期における運動能改善効果 (2003) (0)
- Heart failure: not just the heart but also the lungs. (2012) (0)
- Abstract 9932: Chronic Urotensin II Receptor Blockade Causes Regression of Heart Failure: Beneficial Effects on Neurohormonal Activation, Cardiomyocyte Contractile Function [Ca2+]i Regulation and Beta-Adrenergic Modulation (2012) (0)
- Gadolinium enhanced magnetic resonance mean voxel signal intensity within the left ventricular myocardium changes prior to ejection fraction drop after receipt of cardiotoxic chemotherapy (2009) (0)
- ANGIOGRAPHIC STENOSIS AND ACUTE CORONARY SYNDROMES: PROGRESSION OF STENOSES TO MYOCARDIAL INFARCTION (1997) (0)
- COST-EFFECTIVENESS OF “OFF-LABEL” DRUG ELUTING STENT VERSUS BARE METAL STENT USE (2010) (0)
- Abstract 9356: Diastolic Function Determines the Adrenergic Augmentation of Early Diastolic Intra-Ventriclular Pressure Gradient and Its Spatial Distribution (2011) (0)
- Chemotherapy induced abnormal aortic function assessed by magnetic resonance imaging (2009) (0)
- What differentiates diastolic from systolic heart failure (2003) (0)
- Abstract 2429: Pericardial Fat and Left Ventricular End Diastolic Volume, A Subclinical Marker of Heart Failure with Normal Ejection Fraction: The Multi-Ethnic Study of Atherosclerosis (2008) (0)
- BASELINE SYSTOLIC BLOOD PRESSURE AND OUTCOMES IN PATIENTS WITH HEART FAILURE AND PRESERVED EJECTION FRACTION - RESULTS FROM THE I-PRESERVE TRIAL (2010) (0)
- Abstract 1383: Aging Affects the Response of the Left Atrium to Adrenergic Stress (2009) (0)
- Abstract 3443: Upregulation of {beta}3-Adrenoceptors (AR) as a Contributing Cause of Reduced Positive Modulation of Adrenergic Signaling in Aged Hearts: Evidence from {beta}3-AR Knockout Mice (2008) (0)
- COST EFFECTIVENESS OF EVEROLIMUS-ELUTING COMPARED TO PROPENSITY SCORE MATCHED BARE METAL STENTING: AN ANALYSIS OF A SELECTED STENT STRATEGY (2013) (0)
- 0228 International Session Sarcomere Dynamics in Trabeculae from Rats with Chronic Myocardial Infarction (1996) (0)
- Investigation of the Relationship Between Color M-Mode Early Diastolic Propagation Velocity and Left Ventricular Adverse Pressure Gradients (2010) (0)
- ventricular volumeinpatients withcardiomyopathy (1985) (0)
- Abstract 15884: Inducible Nitric Oxide Synthase Stimulation Depresses Cardiomyocyte Basal and Beta-Adrenergic Response of L-Type Calcium Current in Heart Failure: Insights into the Underlying Electrophysiological Mechanism (2010) (0)
- Abstract 1964: Vascular Complications after Cath and Percutaneous Coronary Intervention: Thrombin Hemostatic Patch Versus Manual Compression (2006) (0)
- COST EFFECTIVENESS OF DRUG-ELUTING STENTS VERSUS BARE METAL STENTS IN CLINICAL PRACTICE: EFFECT OF STENT LENGTH AND DIAMETER (2011) (0)
- COST-EFFECTIVENESS ANALYSIS OF PROPENSITY MATCHED RADIAL AND FEMORAL CARDIAC CATHETERIZATION AND CORONARY INTERVENTION (2012) (0)
- Diastolic Heart Failure Can Be Diagnosed by Comprehensive Two-Dimensional (2006) (0)
- PEAK TROPONIN I GREATER THAN 5 TIMES THE 99TH PERCENTILE AFTER PCI DOES NOT DEFINE A HIGH–RISK GROUP (2013) (0)
- 870-1 Chronic beta3-adrenergic receptor blockade causes regression of cardiac dysfunction in a rat model of progressive heart failure (2004) (0)
- Estimatesof Left-VentricularVolumesby EquilibriumRadionuclideAngiography: Importanceof AttenuationCorrection (2006) (0)
- Mildly Intoxicating Levels of Alcohol Produces Direct Myocardial Depression on Left Ventricular Performance (1992) (0)
- Calculating Intraventricular Pressure Difference Using a Multi-Beat Spatiotemporal Reconstruction of Color M-Mode Echocardiography (2014) (0)
- Abstract 11563: Vasopeptidase Inhibitor, Omapatrilat, Enhances Cardiac Positive Inotropic and Lusitropic Responses to Dobutamine and Exercise in Heart Failure: Assessment by Pressure-Volume Analysis (2013) (0)
- Abstract 12411: Diastolic Function Determines the Prognosis of Myocardial Infarction (2012) (0)
- Smoking while Wearing a Nicotine Patch (1995) (0)
- Qualitative and Quantitative Contrasts in the Mechanisms of Lumen E nlargement by Coronary Ball A io lasty and Directional Coronary At er to y (2016) (0)
- Abstract 17062: Is Up-Regulation of Beta3-Adrenergic Receptor (AR) in the Failing Myocardium Detrimental or Beneficial?--Effect on Chronic Beta3-AR Blockade in Pacing-Induced Heart Failure (2010) (0)
- Abstract 2811: Modulation of Cardiac L-Type Ca2+ Current by Angiotensin-(1-7): Normal vs Heart Failure (2009) (0)
- Lessons About Plaque Rupture Learned from Angiography (2002) (0)
- Abstract 20316: Pulse Wave Velocity During Dobutamine Stress is an Independent Predictor of MACE in Asymptomatic High Risk Middle Aged and Elderly Men (2014) (0)
- THE ARGUMENT FOR EARLY INTERVENTION, ADVANCED LIPOPROTEIN TESTING, AND COMBINATION THERAPY (2002) (0)
- Can Atherosclerotic Progression and Its Complications Be Prevented After Revascularization ? Overview of the Pathogenesis of Bypass Graft Closure and Post-PTCA Restenosis Saphenous Vein Bypass Graft Disease (2005) (0)
- Angiographic assessment of PTCA success underestimates residual stenosis (1991) (0)
- A Hydrodynamic Efficiency Parameter as a Novel Left Ventricular Diastolic Dysfunction Diagnostic Metric (2008) (0)
- The relation between ventricular and pericardial pressures—Can right heart pressure be used to estimate pericardial pressure? (1990) (0)
- Role of Neurohormones and Peripheral Vasculature (2008) (0)
- CATH LAB UTILIZATION DURING TRANSITION TO THE RADIAL ARTERY AS PREFERRED ACCESS: THE WAKE FOREST ACADEMIC MEDICAL CENTER EXPERIENCE (2011) (0)
- TCT-606 Cost Effectiveness of Everolimus-Eluting Stents Compared to Propensity Score Matched Bare Metal Stents in Contemporary Clinical Practice (2012) (0)
- CONTROVERSIES IN CARDIOVASCULAR MEDICINE (2009) (0)
- CARDIOMYOPAT HY Altered elfect of the Valsalva maneuver on left ventricular volume in patients with cardiomyopathy (2005) (0)
- 253 Anemia in diastolic heart failure is frequent and associated with worse outcome (2004) (0)
- Subsequent Myocardial Infarction in Patients With Mild-to-Moderate Coronary Artery Disease? (2005) (0)
- Abstract 9259: Upregulation of Cardiac Urotensin II (UII) Exacerbates UII Stimulation-Induced Negative Modulation on Myocyte Contractile Function and Ca2+ Current in Streptozotocin-Induced Diabetic Rats (2011) (0)
- Nozawa et al Effect of Exercise on Cardiac Mechanical Efficiency 3049 Rest LV (2005) (0)
- Chapter-29 Constrictive Pericarditis (2016) (0)
- 1100 Phase contrast imaging: a novel way of assessing left ventricular diastolic function (2008) (0)
- Abstract 3017: Na+-H+ Exchange Inhibition by Cariporide Enhances Cardiac Positive Inotropic and Lusitropic Responses to Dobutamine in Heart Failure: Assessment by Pressure-Volume Analysis (2009) (0)
- A Relationship Between Pressure Fields and Flow Patterns During Left Ventricular Diastolic Dysfunction Using 2D Phase Contrast MRI (2010) (0)
- Barore flex Activation Therapy for the Treatment of Heart Failure With a Reduced Ejection Fraction (2015) (0)
- Pressure-Volume Loops in Conscious Dogs (2005) (0)
- Abstract MP62: Aortic Root Dilation and Incident Cardiovascular Events in African Americans: The Jackson Heart Study (2016) (0)
- TCT-135 Contrast Use And Acute Kidney Injury In Contemporary Clinical Practice (2012) (0)
- Development and validation of a risk score for predicting death in chagas' heart disease : Can we stop the deaths? (2006) (0)
- Abstract 12766: Early and Persistent Evidence of Subclinical Cardiovascular Injury after Receipt of Anthracycline Chemotherapy. (2010) (0)
- LEFT VENTRICULAR DILATION DECREASES THE CONVECTIVE COMPONENT OF THE EARLY DIASTOLIC INTRAVENTRICULAR PRESSURE (2011) (0)
- 1160-166 C-type natriuretic peptide improves left ventricular performance at rest and during exercise after heart failure (2004) (0)
- TCT-635 Cost Effectiveness Of Everolimus-Eluting Stents Compared To First Generation Drug-Eluting Stents In Contemporary Clinical Practice (2012) (0)
- EFFECT OF POSITIVE END-EXPIRATORY PRESSURE ON LEFT VENTRICULAR CONTRACTILITY (1988) (0)
- Abstract 198: Subclinical Cardiovascular Toxicity of Anthracyclines Identified With Cardiovascular Magnetic Resonance Imaging (2009) (0)
- Comparison ofEffects ofDobutamine andOuabainonLeftVentricular Contraction andRelaxation inClosed-Chest Dogs (1987) (0)
- Abstract 1506: Upregulation of Cardiac AT1 Receptor Signaling Inhibits Myocyte Contractile Performance, [Ca2+]i Transient, and Ca2+ Current in Alcoholic Dogs: Insights into the Underlying Molecular Mechanism (2007) (0)
- Presence of Temporal Non-Uniformity of Early Diastolic Left Ventricular Wall Expansion in Patients with Heart Failure (2015) (0)
- Left Ventricular Systolic Circumferential Deformation is Associated with Left Ventricular Diastolic Apical Suction (2013) (0)
- 1163-113 Predictors of poor outcome in patients with hypertensive pulmonary edema (2004) (0)
- Use of Oral Levosimendan To Treat Congestive Heart Failure: A Pharmacodynamic Versus Pharmacokinetic Relationship Study (2008) (0)
- Acute myocardial infarction (1992) (0)
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What Schools Are Affiliated With William Clarke Little?
William Clarke Little is affiliated with the following schools:
