William F. Blakemore
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Biology
Why Is William F. Blakemore Influential?
(Suggest an Edit or Addition)William F. Blakemore's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Repair of demyelinated lesions by transplantation of purified 0-2A progenitor cells (1993) (424)
- Remyelination protects axons from demyelination-associated axon degeneration. (2008) (374)
- Response of the oligodendrocyte progenitor cell population (defined by NG2 labelling) to demyelination of the adult spinal cord (1998) (363)
- Central remyelination restores secure conduction (1979) (303)
- Remyelination occurs as extensively but more slowly in old rats compared to young rats following gliotoxin‐induced CNS demyelination (1999) (271)
- Remyelination in experimental models of toxin-induced demyelination. (2008) (250)
- Inflammation stimulates remyelination in areas of chronic demyelination. (2005) (218)
- Observations on oligodendrocyte degeneration, the resolution of status spongiosus and remyelination in cuprizone intoxication in mice (1972) (196)
- Locomotor deficits induced by experimental spinal cord demyelination are abolished by spontaneous remyelination. (1997) (194)
- Local recruitment of remyelinating cells in the repair of demyelination in the central nervous system (1997) (183)
- Polysialylated Neural Cell Adhesion Molecule-Positive CNS Precursors Generate Both Oligodendrocytes and Schwann Cells to Remyelinate the CNS after Transplantation (1999) (181)
- Pattern of remyelination in the CNS (1974) (180)
- Remyelination of CNS axons by Schwann cells transplanted from the sciatic nerve (1977) (178)
- The use of cultured autologous Schwann cells to remyelinate areas of persistent demyelination in the central nervous system (1985) (173)
- The restoration of conduction by central remyelination. (1981) (169)
- Remyelination of mouse spinal cord axons demyelinated by local injection of lysolecithin (1995) (165)
- The effect of L3T4 T cell depletion on the pathogenesis of Theiler's murine encephalomyelitis virus infection in CBA mice. (1987) (163)
- Remyelination by Schwann cells of axons demyelinated by intraspinal injection of 6-aminonicotinamide in the rat (1975) (151)
- Efficient recolonisation of progenitor‐depleted areas of the CNS by adult oligodendrocyte progenitor cells (2002) (151)
- The origin of remyelinating cells in the central nervous system (1999) (150)
- Requirements for schwann cell migration within cns environments: A viewpoint (1993) (147)
- Transplanted CG4 Cells (an Oligodendrocyte Progenitor Cell Line) Survive, Migrate, and Contribute to Repair of Areas of Demyelination in X-Irradiated and Damaged Spinal Cord but Not in Normal Spinal Cord (1996) (146)
- Cellular pathology of the central nervous system. (2002) (142)
- The role of oligodendrocytes and oligodendrocyte progenitors in CNS remyelination. (1999) (137)
- Remyelination in the spinal cord of the cat following intraspinal injections of lysolecithin (1977) (134)
- Transplanted type-1 astrocytes facilitate repair of demyelinating lesions by host oligodendrocytes in adult rat spinal cord (1991) (131)
- Glial-cell transplantation and plasticity in the O-2A lineage — implications for CNS repair (1995) (117)
- Pathogenesis of meningitis caused by Streptococcus suis type 2. (1990) (116)
- Transplantation of glial cells into the CNS (1991) (110)
- The relationship between type-1 astrocytes, Schwann cells and oligodendrocytes following transplantation of glial cell cultures into demyelinating lesions in the adult rat spinal cord (1989) (107)
- Failure to achieve remyelination of demyelinated rat axons following transplantation of glial cells obtained from the adult human brain (1996) (99)
- Observations on the interactions of Schwann cells and astrocytes following X-irradiation of neonatal rat spinal cord (1975) (94)
- The subependymal plate and associated ependyma in the dog. An ultrastructural study (1972) (93)
- Biochemical studies on a case of feline mannosidosis. (1980) (89)
- Oligodendrocyte precursors survive poorly and do not migrate following transplantation into the normal adult central nervous system (1997) (87)
- Behavioural consequences of oligodendrocyte progenitor cell transplantation into experimental demyelinating lesions in the rat spinal cord (1999) (85)
- Extensive oligodendrocyte remyelination following injection of cultured central nervous system cells into demyelinating lesions in adult central nervous system. (1988) (84)
- Schwann Cells Transplanted into Normal and X-Irradiated Adult White Matter Do Not Migrate Extensively and Show Poor Long-Term Survival (2000) (82)
- Modelling large areas of demyelination in the rat reveals the potential and possible limitations of transplanted glial cells for remyelination in the CNS (2002) (79)
- Age increases axon loss associated with primary demyelination in cuprizone-induced demyelination in C57BL/6 mice (2006) (75)
- Observations on wallerian degeneration in explant cultures of cat sciatic nerve (1986) (73)
- Schwann cell precursors: a favourable cell for myelin repair in the Central Nervous System. (2007) (72)
- Decline in Rate of Colonization of Oligodendrocyte Progenitor Cell (OPC)‐Depleted Tissue by Adult OPCs with Age (2003) (72)
- Lines of glial precursor cells immortalised with a temperature‐sensitive oncogene give rise to astrocytes and oligodendrocytes following transplantation into demyelinated lesions in the central nervous system (1993) (66)
- Environmental signals regulate lineage choice and temporal maturation of neural stem cells from human embryonic stem cells. (2007) (64)
- The presence of astrocytes in areas of demyelination influences remyelination following transplantation of oligodendrocyte progenitors (2003) (64)
- Transplantation Options for Therapeutic Central Nervous System Remyelination (2000) (62)
- Limited remyelination of CNS axons by Schwann cells transplanted into the sub-arachnoid space (1984) (60)
- New insights into remyelination failure in multiple sclerosis: implications for glial cell transplantation (2002) (59)
- Differential generation of oligodendrocytes from human and rodent embryonic spinal cord neural precursors (2004) (59)
- Ultrastructural changes in isoniazid-induced brain oedema in the dog (1972) (58)
- Transplanted glial cells migrate over a greater distance and remyelinate demyelinated lesions more rapidly than endogenous remyelinating cells (2000) (57)
- Remyelination of demyelinated rat axons by transplanted mouse oligodendrocytes (1991) (56)
- Use of a rat Y chromosome probe to determine the long-term survival of glial cells transplanted into areas of CNS demyelination (1997) (54)
- Depletion of endogenous oligodendrocyte progenitors rather than increased availability of survival factors is a likely explanation for enhanced survival of transplanted oligodendrocyte progenitors in X‐irradiated compared to normal CNS (2001) (53)
- The ultrastructure of the subependymal plate in the rat. (1969) (52)
- To what extent is oligodendrocyte progenitor migration a limiting factor in the remyelination of multiple sclerosis lesions? (1997) (52)
- Schmidt-Lantermann incisures in the central nervous system. (1969) (52)
- The differentiation of glial cell progenitor populations following transplantation into non-repairing central nervous system glial lesions in adult animals (1992) (52)
- Remyelination in the CNS. (1981) (52)
- Suppression of remyelination in the CNS by X-irradiation (1978) (51)
- The demonstration by transplantation of the very restricted remyelinating potential of post-mitotic oligodendrocytes (1998) (50)
- Observation on the presence of Listeria monocytogenes in axons. (1989) (48)
- Glial cell transplants that are subsequently rejected can be used to influence regeneration of glial cell environments in the CNS (1995) (47)
- GM1 GANGLIOSIDOSIS IN A CAT (1972) (46)
- The remyelinating potential and in vitro differentiation of MOG‐expressing oligodendrocyte precursors isolated from the adult rat CNS (2004) (45)
- A different regional response by mouse oligodendrocyte progenitor cells (OPCs) to high‐dose X‐irradiation has consequences for repopulating OPC‐depleted normal tissue (2007) (43)
- Cerebellar hypoplasia and degeneration in the young Arab horse: clinical and neuropathological features (1973) (42)
- The effects of the growth factor‐antagonist, trapidil, on remyelination in the CNS (1997) (41)
- Schwann cell remyelination is not replaced by oligodendrocyte remyelination following ethidium bromide induced demyelination (2002) (41)
- Type 1 astrocytes fail to inhibit Schwann cell remyelination of CNS axons in the absence of cells of the O-2A lineage. (1992) (41)
- The catabolism of mammalian glycoproteins. Comparison of the storage products in bovine, feline and human mannosidosis. (1983) (40)
- Spinal cord injury in small animals 1. Mechanisms of spontaneous recovery (1999) (38)
- A murine model of Streptococcus suis type 2 meningitis in the pig. (1988) (38)
- Inherited lysosomal storage diseases: an essay in comparative medicine (1973) (37)
- The role of astrocytes in the remyelination of glia-free areas of demyelination. (1993) (37)
- The reconstruction of an astrocytic environment in glia-deficient areas of white matter (1993) (36)
- Transplantation options for therapeutic central nervous system remyelination. (2000) (36)
- Primary demyelination and regeneration of ascending axons in the dorsal funiculus of the rat spinal cord following photochemically induced injury (1996) (36)
- Effects of direct transplantation of multipotent mesenchymal stromal/stem cells into the demyelinated spinal cord. (2008) (34)
- Oligodendrocyte Progenitor Cells in the Adult Rat CNS Express Myelin Oligodendrocyte Glyco‐protein (MOG) (2002) (33)
- The ultrastructure of normal and reactive microglia. (1975) (33)
- Neurovisceral Glucocerebroside Storage (Gaucher's Disease) in a Dog (1973) (32)
- A Quantifiable Model of Axonal Regeneration in the Demyelinated Adult Rat Spinal Cord (1998) (32)
- A New Method of Quantifying the Extent of Tissue Loss Following Spinal Cord Injury in the Rat (1996) (32)
- Observations on demyelinating lesions induced by Theiler's virus in CBA mice (2004) (31)
- Investigation of the role of delayed-type-hypersensitivity responses to myelin in the pathogenesis of Theiler's virus-induced demyelinating disease. (1998) (31)
- Reconstruction of the glial environment of a photochemically induced lesion in the rat spinal cord by transplantation of mixed glial cells (1996) (30)
- GM1 gangliosidosis (type 1) in a cat. (1986) (29)
- Observations on the migratory behaviour of Schwann cells from adult peripheral nerve expiant cultures (1987) (29)
- Dependence of axolemmal differentiation on contact with glial cells in chronically demyelinated lesions of cat spinal cord (1985) (28)
- Areas of demyelination do not attract significant numbers of Schwann cells transplanted into normal white matter (2000) (28)
- Ultrastructural observations on the spinal cord of a Landrace pig with congenital tremor type AIII. (1974) (26)
- Spinal cord injury in small animals 2. Current and future options for therapy (1999) (26)
- The effect of the number of oligodendrocytes transplanted into X-irradiated, glial-free lesions on the extent of oligodendrocyte remyelination (1989) (26)
- Schwann cell remyelination of CNS axons following injection of cultures of CNS cells into areas of persistent demyelination (1987) (26)
- The enzymic defect and storage products in canine fucosidosis. (1984) (25)
- Remyelination through Engraftment (2004) (25)
- Structural specializations in cat of chronically demyelinated spinal cord axons as seen in freeze-fracture replicas (1984) (24)
- Decompression sickness in the goat: nature of brain and spinal cord lesions at 48 hours. (1978) (24)
- Remyelination occurs as extensively but more slowly in old rats compared to young rats following fliotoxin‐induced CNS demyelination (2000) (24)
- A case of mannosidosis in the cat: clinical and histopathological findings (1986) (23)
- Effects of Direct Transplantation of Multipotent Mesenchymal Stromal/Stem Cells into the Demyelinated Spinal Cord (2008) (23)
- Transplanted cultured type‐1 astrocytes can be used to reconstitute the glia limitans of the CNS: the structure which prevents Schwann cells from myelinating CNS axons (1992) (23)
- The interaction of Schwann cells with CNS axons in regions containing normal astrocytes (2004) (22)
- An Unidentified Sporozoan Encephalomyelitis in Sheep (1974) (22)
- Ataxia and spinal cord degeneration in llama, wildebeeste and camel (1980) (22)
- Ocular lesions in cats with GM1-gangliosidosis with visceral involvement. (1977) (20)
- Repopulation of oligodendrocyte progenitor cell‐depleted tissue in a model of chronic demyelination (2005) (20)
- Remyelinating the demyelinated CNS. (2000) (20)
- Nervous disease in the chihuahua characterised by axonal swellings (1985) (19)
- Remyelination of Demyelinated CNS Axons by Transplanted Human Schwann Cells: The Deleterious Effect of Contaminating Fibroblasts (2001) (19)
- Restoration of secure conduction by central demyelination. (1979) (19)
- Oligodendrocyte progenitor cell (OPC) transplantation is unlikely to offer a means of preventing X-irradiation induced damage in the CNS (2006) (19)
- Monocyte recruitment into the scrapie-affected brain (2004) (18)
- Enzymological characterization of a feline analogue of primary hyperoxaluria type 2: a model for the human disease (1989) (17)
- Rat Schwann cell remyelination of demyelinated cat CNS axons: evidence that injection of cell suspensions of CNS tissue results in Schwann cell remyelination (1987) (17)
- Endogenous or exogenous oligodendrocytes for remyelination (2008) (17)
- Tremor syndrome and hypomyelination in Lurcher pups (1984) (17)
- The behaviour of meningeal cells following glial cell transplantation into chemically‐induced areas of demyelination in the CNS (1992) (17)
- Remyelination of demyelinated CNS axons by transplanted human schwann cells: the deleterious effect of contaminating fibroblasts. (2001) (16)
- The peripheral nervous system--central nervous system regeneration dichotomy: a role for glial cell transplantation. (1990) (16)
- Neurovisceral storage and dysmyelinogenesis in neonatal goats (2004) (15)
- Inherited copper toxicosis in the Bedlington terrier: a report of two clinical cases (1987) (15)
- Evidence of oligodendrocyte infection and degeneration in canine distemper encephalomyelitis (2004) (15)
- A progressive neuronopathy in the young cairn terrier (1989) (15)
- Reconstruction of the glia limitans by sub‐arachnoid transplantation of astrocyte‐enriched cultures (1995) (14)
- Transplantation of glial cell cultures into areas of demyelination in the adult CNS. (1990) (14)
- Glial grafting for demyelinating disease (2005) (14)
- Attempts to produce astrocyte cultures devoid of oligodendrocyte generating potential by the use of antimitotic treatment reveal the presence of quiescent oligodendrocyte precursors (1997) (13)
- Glial cell transplantation and the repair of demyelinating lesions (1997) (13)
- Primary hyperoxaluria andl-glyceric aciduria in the cat (1988) (13)
- Ultrastructural observations on the spinal cords of piglets affected with congenital tremor type AIV. (1974) (13)
- Neuropathological findings in a Staffordshire bull terrier with l-2-hydroxyglutaric aciduria. (2008) (12)
- Generalised ceroid-lipofuscinosis and brown bowel syndrome in Cocker spaniel dogs. (1994) (12)
- GM-1 gangliosidosis in a cat. (1972) (11)
- The effect of injection technique on the passive spread of astrocytes following transplantation into rat spinal cord white matter. (1995) (10)
- The use of xenografting to evaluate the remyelinating potential of glial cell cultures (1994) (10)
- Progressive ataxia of Charolais cattle associated with disordered myelin (2004) (9)
- The number of cells expressing the myelin-supporting oligodendrocyte marker PLP-exon 3b remains unchanged in Wallerian degeneration. (2004) (9)
- Ultrastructural findings in spongy degeneration of white matter in silver foxes (Vulpes vulpes) (2004) (8)
- Haplotype matching is not an essential requirement to achieve remyelination of demyelinating CNS lesions (2006) (8)
- Node-like axonal specialisations along demyelinated central nerve fibres: Ultrastructural observations (2004) (8)
- Lesions in the cat spinal cord following local injections of 6-aminonicotinamide. (1978) (7)
- Rejection of wild-type and genetically engineered major histocompatibility complex-deficient glial cell xenografts in the central nervous system results in bystander demyelination and Wallerian degeneration (1998) (7)
- Intracranial germ cell tumours in two dogs (1989) (6)
- Animal Models for GM1 Gangliosidosis (1974) (5)
- Repair of demyelinated lesions by glial cell transplantation (1994) (5)
- Neurolipidoses: examples of lysosomal storage diseases. (1980) (5)
- The Transplantation of Glial Cells into Areas of Primary Demyelination (1990) (5)
- Biochemical evidence for a case of canine fucosidosis (1984) (5)
- Recent Insights into the Cellular Biology of Remyelination (1997) (5)
- Node-like axonal undercoating in the optic nerve of heterozygous myelin-deficient rats (1987) (4)
- Canine fucosidosis (1985) (4)
- Lymphocyte-myelin sheath interactions in acute experimental allergic encephalomyelitis (1989) (4)
- Olfactory glia and CNS repair: a step in the road from proof of principle to clinical application. (2000) (4)
- Progressive neuronopathy in the cairn terrier (1988) (4)
- Transplanting myelin-forming cells into the central nervous system: principles and practice. (1998) (3)
- Bovine Spongiform Encephalopathy and Scrapie: Potential Human Hazards (1989) (2)
- A rat spinal subarachnoid continuous infusion device (1995) (2)
- Areas of Demyelination Repaired by Mouse Oligodendrocytes and Rat Type-1 Astrocytes Create a New Model of Immune Mediated Demyelination (1994) (2)
- Transplanting Myelinogenic Cells into the CNS (2000) (1)
- RELIEF OF CENTRAL CONDUCTION BLOCK BY REMYELINATION (1979) (0)
- Photochemically induced spinal ischaemia: a model of spinal cord trauma in the rat (1995) (0)
- Rejection of xenogeneic glial cells grafted into spinal cord white matter results in bystander demyelination (1995) (0)
- Chapter 212 – Glucocerebrosidosis (Gaucher's Disease) (1979) (0)
- Remyelination by PSA-NCAM+ neural precursor cell spheres (1998) (0)
- Theenzymic defect andstorage products incanine fucosidosis (1984) (0)
- Lysosomal storage diseases. (1980) (0)
- Transplantation of Myelin-Forming Cells (2004) (0)
- The repair of damaged glial environments by transplanted astrocytes (1995) (0)
- [abstract] PATHOLOGICAL CHANGES IN THE SPINAL CORD OF GOATS WITH EXPERIMENTAL DECOMPRESSION SICKNESS (1977) (0)
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