William John Louis
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Medical Philosophy
William John Louis's Degrees
- Doctorate Cardiology Stanford University
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(Suggest an Edit or Addition)William John Louis's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Atrial fibrillation after coronary artery bypass grafting is associated with sympathetic activation. (1995) (370)
- Plasma norepinephrine levels in essential hyoertension. (1973) (281)
- Omeprazole: a study of its inhibition of gastric pH and oral pharmacokinetics after morning or evening dosage. (1985) (188)
- Effects of sodium intake on inherited hypertension in the rat. (1971) (137)
- Genealogy of the Spontaneously Hypertensive Rat and Wistar‐Kyoto Rat Strains: Implications for Studies of Inherited Hypertension (1990) (119)
- Risk factors for cardiovascular disease in chronic spinal cord injury patients (1992) (114)
- Perhexiline maleate treatment for severe angina pectoris--correlations with pharmacokinetics. (1986) (113)
- Fluorouracil Therapy in Patients with Carcinoma of the Large Bowel: A Pharmacokinetic Comparison of Various Rates and Routes of Administration (1978) (109)
- Medial prefrontal cortical lesions modulate baroreflex sensitivity in the rat (1987) (106)
- Combined use of nitroglycerin and N-acetylcysteine in the management of unstable angina pectoris. (1988) (104)
- A comparison of beta adrenergic blocking drugs in the treatment of hypertension (1974) (104)
- Plasma dopamine -hydroxylase and noradrenaline amounts in essential hypertension. (1973) (103)
- HYPERTENSIVE RESPONSES INDUCED BY PHENYLPROPANOLAMINE IN ANORECTIC AND DECONGESTANT PREPARATIONS (1980) (95)
- Blood-brain barrier disruption using mannitol: time course and electron microscopy studies. (1989) (95)
- Effect of daily oral omeprazole on 24 hour intragastric acidity. (1983) (91)
- Comparison of liquid- and gas-liquid chromatographic assays of 5-fluorouracil in plasma. (1979) (91)
- Verapamil in the Treatment of Hypertension (1981) (89)
- Effects of pravastatin on cardiovascular reactivity to norepinephrine and angiotensin II in patients with hypercholesterolemia and systemic hypertension. (1995) (87)
- Catecholamine Metabolism in Hypertensive Rats (1970) (83)
- Beta-adrenergic receptor blocking drugs, hypertension and plasma renin. (1975) (79)
- Plasma Renin Levels and Vascular Complications in Hypertension (1973) (77)
- Synthesis and Turnover of Norepinephrine in the Heart of the Spontaneously Hypertensive Rat (1969) (69)
- Quantitative autoradiographic localization in rat brain of α 2-adrenergic and non-adrenergic I-receptor binding sites labelled by [3H]rilmenidine (1995) (69)
- The relationship of plasma levels of pindolol in hypertensive patients to effects on blood pressure, plasma renin and plasma noradrenaline levels (1975) (68)
- Nitroglycerin-induced tolerance affects multiple sites in the organic nitrate bioconversion cascade. (1989) (67)
- High-performance liquid chromatographic analysis of captopril in plasma. (1981) (66)
- Anticonvulsant effects of clonidine mediated through central α2-adrenoceptors (1982) (65)
- Impaired arterial baroreceptor reflex and cardiopulmonary vagal reflex in conscious spontaneously hypertensive rats. (1990) (59)
- Clinical Pharmacokinetics of Labetalol (1984) (56)
- Pressor dose responses and baroreflex sensitivity in quadriplegic spinal cord injury patients (1992) (54)
- Long-Term Use of Intranasal Insulin in Insulin-Dependent Diabetic Patients (1987) (53)
- The effects of dietary lipid modification on blood pressure, cardiovascular reactivity and sympathetic activity in man (1993) (52)
- Studies on the spontaneously hypertensive rat. Genealogy, effects of varying salt intake, and kinetics of catecholamine metabolism. (1969) (51)
- Quantitative Limulus lysate assay for endotoxin and the effect of plasma. (1991) (51)
- THE CHARACTERISTICS OF [3H]‐CLONIDINE BINDING TO ANα‐ADRENOCEPTOR IN MEMBRANES FROM GUINEA‐PIG KIDNEY (1979) (51)
- THE USE OF PRINDOLOL (VISKEN) IN THE TREATMENT OF HYPERTENSION (1972) (50)
- Angiotensin II Receptors and Angiotensin Converting Enzyme in the Medulla Oblongata (1987) (49)
- Age related changes of catecholamines and their metabolites in central nervous system regions of spontaneously hypertensive (SHR) and normotensive Wistar-Kyoto (WKY) rats. (1984) (49)
- Expression of c-fos and NGFI-A messenger RNA in the medulla oblongata of the anaesthetized rat following stimulation of vagal and cardiovascular afferents. (1992) (48)
- Plasma noradrenaline concentration and blood pressure in essential hypertension, phaeochromocytoma and depression. (1975) (48)
- Plasma catecholamine and dopamine -hydroxylase amounts in phaeochromocytoma. (1973) (47)
- Antibiotic-induced release of endotoxin in chronically bacteriuric patients (1991) (47)
- ROLE OF CENTRAL β‐ADRENOCEPTORS IN THE CONTROL OF PENTYLENETETRAZOL‐INDUCED CONVULSIONS IN RATS (1982) (47)
- Effects of intranasal insulin in non-obese type II diabetics. (1987) (45)
- A double-blind crossover comparison of pindolol, metoprolol, atenolol and labetalol in mild to moderate hypertension. (1979) (45)
- Use of computerized neuropsychological tests (CANTAB) to assess cognitive effects of antihypertensive drugs in the elderly. Cambridge Neuropsychological Test Automated Battery. (1999) (45)
- Failure of psychosocial stress to induce chronic hypertension in the rat. (1984) (44)
- Selectivity of a series of clonidine-like drugs for α 1 and α 2 adrenoceptors in rat brain (1980) (43)
- The relationship between α2-adrenoceptor selectivity and anticonvulsant effect in a series of clonidine-like drugs (1982) (43)
- Diurnal blood pressure variation in quadriplegic chronic spinal cord injury patients. (1991) (42)
- Short term effects of pravastatin on blood pressure in hypercholesterolaemic hypertensive patients. (1994) (42)
- Measurement of carbamazepine and its epoxide metabolite by high-performance liquid chromatography, and a comparison of assay techniques for the analysis of carbamazepine. (1977) (42)
- Pharmacokinetic properties of captopril after acute and chronic administration to hypertensive subjects. (1982) (41)
- The effect of levcromakalim (BRL 38227) on bladder function in patients with high spinal cord lesions. (1995) (41)
- A Pharmacokinetic Study of Carvedilol (BM 14.190) in Elderly Subjects: Preliminary Report (1987) (41)
- Taste loss associated with captopril treatment. (1979) (40)
- Stable oral availability of sustained release propranolol when co-administered with hydralazine or food: evidence implicating substrate delivery rate as a determinant of presystemic drug interactions. (1984) (40)
- The effect of a series of clonidine analogues on [3H] clonidine binding in rat cerebral cortex. (1979) (40)
- Functional angiotensin II type 2 receptors inhibit growth factor signaling in LNCaP and PC3 prostate cancer cell lines (2008) (40)
- Double blind comparative study of omeprazole 10 mg and 30 mg daily for healing duodenal ulcers. (1985) (39)
- Short-term myocardial uptake of lidocaine and mexiletine in patients with ischemic heart disease. (1986) (39)
- [3H]‐GUANFACINE: A RADIOLIGAND THAT SELECTIVELY LABELS HIGH AFFINITY α2‐ADRENOCEPTOR SITES IN HOMOGENATES OF RAT BRAIN (1982) (39)
- A study of the alpha-1 adrenoceptor blocker prazosin in the prophylactic management of autonomic dysreflexia in high spinal cord injury patients (1992) (39)
- A study of the interactive effects of oral contraceptive use and dietary fat intake on blood pressure, cardiovascular reactivity and glucose tolerance in normotensive women (1998) (39)
- Preprogalanin mRNA is increased in vagal motor neurons following axotomy. (1992) (38)
- High-performance liquid chromatographic assay of perhexiline maleate in plasma. (1981) (37)
- Hypotensive effect of low-fat, high-carbohydrate diet can be independent of changes in plasma insulin concentrations. (1999) (37)
- Ocular side effects with 5-fluorouracil. (1979) (36)
- Displacement of [3H]clonidine binding by clonidine analogues in membranes from rat cerebral cortex. (1980) (36)
- Cardiovascular and vasoactive hormone responses to bladder distension in spinal and normal man (1992) (36)
- Comparative Trial of Mexiletine and Lignocaine in the Treatment of Early Ventricular Tachyarrhythmias After Acute Myocardial Infarction (1981) (34)
- Inheritance of high blood-pressure in the spontaneously hypertnsive rat. (1969) (34)
- Secretion of Dopa in Phaeochromocytoma (1972) (33)
- Serotonin levels in vascular tissue and the effects of a serotonin synthesis inhibitor on blood pressure in hypertensive rats. (1975) (33)
- Labetalol: bioavailability, drug plasma levels, plasma renin and catecholamines in acute and chronic treatment of resistant hypertension. (1978) (32)
- Determinants of In Vitro Nitroglycerin Tolerance Induction and Reversal: Influence of Dose Regimen, Nitrate‐Free Period, and Sulfhydryl Supplementation (1989) (32)
- Methicillin-resistant Staphylococcus aureus in an Australian teaching hospital. (1984) (32)
- Pharmacokinetics and pharmacodynamic studies of labetalol in hypertensive subjects. (1979) (32)
- Pharmacokinetics and pharmacodynamic studies of labetalol in hypertensive subjects. (1979) (32)
- Excitotoxin-induced lesions of the central but not basolateral nucleus of the amygdala modulate the baroreceptor heart rate reflex in conscious rats (1989) (30)
- Left ventricular function in uremia: echocardiographic assessment in patients on maintenance dialysis. (1981) (30)
- Intrathecal kynurenate reduces arterial pressure, heart rate and baroreceptor-heart rate reflex in conscious rats (1990) (28)
- Role of the renin–angiotensin system in prostate cancer (2009) (27)
- Impairment of inhibitory cardiopulmonary vagal reflexes in spontaneously hypertensive rats. (1988) (27)
- Steady state plasma [3H]-noradrenaline kinetics in quadriplegic chronic spinal cord injury patients. (1990) (27)
- Impact of a toxicology service on a metropolitan teaching hospital. (2001) (27)
- LK 204-545, a highly selective beta1-adrenoceptor antagonist at human beta-adrenoceptors. (1999) (26)
- Expression and function of ATIP/MTUS1 in human prostate cancer cell lines (2010) (26)
- Combined gas chromatographic-mass spectrometric procedure for the measurement of captopril and sulfur-conjugated metabolites of captopril in plasma and urine. (1984) (26)
- Increase in galanin and neuropeptide Y mRNA in locus coeruleus following acute reserpine treatment. (1990) (26)
- Pharmacokinetic and pharmacodynamic studies of oral clonidine in normotensive subjects (2004) (25)
- Abnormalities in enzymes involved in catecholamine synthesis and catabolism in phaeochromocytoma. (1977) (25)
- Evaluation of Indapamide in the Treatment of Hypertension (1979) (24)
- Nitroglycerine/N-acetylcysteine in the management of unstable angina pectoris. (1988) (24)
- α2-adrenoceptor and catecholamine-insensitive binding sites for [3H]rilmenidine in membranes from rat cerebral cortex (1992) (24)
- Role of β-Adrenergic Receptor Subtypes in Lipolysis (2000) (23)
- Adrenaline and phenylethanolamine‐N‐methyltransferase in rat medullary and anterior hypothalamic‐preoptic nuclei (1979) (23)
- Effects of antihypertensive drugs in the spontaneously hypertensive rat (1970) (22)
- Blood pressure variability in tetraplegic patients with autonomic hyperreflexia (1989) (22)
- Cardiac alpha-adrenoceptors involving positive chronotropic responses. (1985) (22)
- Appearance of angiotensin II expression in non-basal epithelial cells is an early feature of malignant change in human prostate. (2007) (21)
- POSITIVE CHRONOTROPIC RESPONSES PRODUCED BY α-ADRENORECEPTORS IN THE PITHED RAT (1982) (21)
- Single‐Dose and Steady‐State Pharmacokinetics and Pharmacodynamics of Perindopril in Hypertensive Subjects (1992) (21)
- Labetalol steady-state pharmacokinetics in hypertensive patients. (1982) (21)
- Role of β‐adrenoceptors in the anticonvulsant effect of propranolol on leptazol‐induced convulsions in rats (1982) (20)
- Noradrenaline in the heart of the spontaneously hypertensive rat. (1968) (20)
- Induction of c‐jun expression in vagal motoneurones following axotomy (1992) (20)
- The effects of varying doses of angiotensin on renal function and blood pressure in man and dogs. (1965) (20)
- Pharmacology of combined alpha-beta-blockade. I. (1984) (20)
- The effect of acute α-methyldopa administration on catecholamine levels in anterior hypothalamic-preoptic and medullary nuclei in rat brain (1979) (19)
- Excitatory amino acid receptors in the caudal ventrolateral medulla mediate a vagal cardiopulmonary reflex in the rat (2004) (19)
- Age related changes of noradrenaline content in brain regions of spontaneously hypertensive (SHR) and normotensive Wistar-Kyoto (WK) rats. (1983) (18)
- Nitrate Tolerance Induced by Nicorandil or Nitroglycerin is Associated with Minimal Loss of Nicorandil Vasodilator Activity (1990) (18)
- Comparison of intravenous and oral high-dose methotrexate in treatment of solid tumours. (1979) (18)
- The use of a double-isotope derivative plasma assay for noradrenaline and adrenaline in the diagnosis and localisation of phaeochromocytoma. (1971) (18)
- Determinants of Acute Hemodynamic and Electrophysiologic Effects of Verapamil in Humans: Role of Myocardial Drug Uptake (1990) (17)
- Effects of captopril (SQ 14,225) in a patient with primary pulmonary hypertension. (1981) (17)
- The involvement of central alpha adrenoceptors in the antihypertensive actions of methyldopa and clonidine in the rat. (1984) (17)
- Cardiac α-adrenoceptors: postjunctional and prejunctional (1986) (17)
- The influence of age and sex on cardiac, renal and caudal artery catecholamine content in spontaneously hypertensive (SHR) and Wistar Kyoto (WKY) rats. (1986) (16)
- Effects of continuous infusions (10 days) and cessation of infusions of clonidine and rilmenidine (S 3341) on cardiovascular and behavioral parameters of spontaneously hypertensive rats. (1988) (16)
- Tissue Distribution and Hypotensive Effect of Prazosin in the Conscious Rat (1983) (16)
- Metabolism and blood levels following infusion of a radioactive analog of angiotensin. (1968) (16)
- Partial Agonist Activity of Celiprolol (1993) (16)
- Actions of dilevalol on adrenoceptors. (1988) (16)
- CARDIOVASCULAR EFFECTS OF DOPAMINE IN THE ANAESTHETIZED DOG (1974) (16)
- Medial prefrontal cortical lesions and baroreceptor heart rate reflex sensitivity in the spontaneously hypertensive rat. (1988) (16)
- Acute myocardial uptake of digoxin in humans: correlation with hemodynamic and electrocardiographic effects. (1990) (16)
- Effect of Age on Pharmacokinetics of and Blood Pressure Responses to Prazosin and Terazosin (1987) (16)
- Plasma angiotensinase activity on angiotensin II and analogues. (1967) (15)
- The measurement of central noradrenergic activity in spontaneously hypertensive rats: a comparison of free 3,4-dihydroxyphenylethyleneglycol levels with FLA-63 induced noradrenaline depletion. (1985) (15)
- ADRENALINE DEPLETION IN THE HYPOTHALAMUS OF THE RAT AFTER CHRONIC α‐METHYLDOPA (1981) (15)
- Lacrimation and 5-fluorouracil. (1978) (15)
- [3H]2-(2-Benzofuranyl)-2-imidazoline, a highly selective radioligand for I2-imidazoline receptor binding sites Studies in rabbit kidney membranes (1996) (15)
- Excitotoxin-induced degeneration of rat vagal afferent neurons (1990) (15)
- Characterization of alpha-adrenoceptors in rat and guinea pig tissues using radiolabeled agonists and antagonists. (1980) (15)
- Acute and chronic administration of α-methyldopa: Regional levels of endogenous and α-methylated catecholamines in rat brain (1978) (15)
- Phaeochromocytoma in the elderly: a poorly recognised entity? (1986) (14)
- Effects of dietary lipid modification on adrenoceptor-mediated cardiovascular responsiveness and baroreflex sensitivity in normotensive subjects. (1997) (14)
- Pharmacology of Combined α-β-Blockade I (2012) (14)
- Role of beta-adrenergic receptor subtypes in lipolysis. (2000) (14)
- Postural hypotension in elderly patients given carvedilol (1994) (14)
- Pharmacokinetics and Antihypertensive Effects of Low Dose Clonidine During Chronic Therapy (1989) (13)
- Renal clearance of methotrexate in man during high-dose oral and intravenous infusion therapy (2004) (13)
- Single and chronic dose pharmacokinetic studies of sodium valproate in epileptic patients (1979) (13)
- Calcium antagonists inhibit positive chronotropic responses to alpha 1-adrenoceptor activation in rat isolated atria. (1987) (13)
- Left ventricular aneurysm repair in rats: structural, functional, and molecular consequences. (2001) (13)
- Beta-adrenoceptor blocking drugs: the relevance of intrinsic sympathomimetic activity. (1982) (12)
- COMPARISON OF METOPROLOL AND PINDOLOL IN THE TREATMENT OF MILD TO MODERATE HYPERTENSION: A DOUBLE‐BLIND CROSSOVER STUDY (1979) (12)
- Antihypertensive efficacy and safety of perindopril in mild-to-moderate essential hypertension: results of a double-blind multicenter study versus atenolol. (1992) (12)
- Anticonvulsant effects of clonidine mediated through central alpha2-adrenoceptors. (1982) (12)
- Acute effects of blood pressure elevation on insulin clearance in normotensive healthy subjects. (1998) (12)
- Distribution of Nonadrenergic [3H]Rilmenidine Binding in Rat Brain and Kidney a (1995) (12)
- Comparison of [3H]clonidine and [3H]guanfacine binding to α 2 adrenoceptors in membranes from rat cerebral cortex (1981) (12)
- Effects of methyldopa metabolites on amine transmitters and adrenergic receptors in rat brain. (1984) (12)
- Antihypertensive and noradrenaline-depleting effects of α-methyl-5-hydroxytryptophan in the rat (1969) (11)
- Effect of dorsal periaqueductal grey lesion on baroreflex and cardiovascular response to air-jet stress. (1995) (11)
- Pharmacokinetics of Prazosin in Normotensive Subjects After Low Oral Doses (1980) (11)
- Plasma renin and angiotensin levels in human hypertension following treatment. (1973) (11)
- Atrial tachyarrhythmias following coronary bypass surgery : sympathetic mechanisms (1992) (11)
- Saturable metabolism of perhexiline maleate: Correlations with long-term toxicity (1981) (10)
- Differential characteristics and localisation of [3H]oxazoline and [3H]imidazoline binding sites in rat kidney. (1995) (10)
- Altered cardiac hormone and contractile protein messenger RNA levels following left ventricular myocardial infarction in the rat: an in situ hybridization histochemical study. (1998) (10)
- Increase in plasma cholesterol on subjects' standing correlates with the increase in plasma norepinephrine. (1988) (10)
- Neurotransmitters and neuropeptides in blood pressure regulation in the spontaneously hypertensive rat. (1987) (10)
- Influence of food on the bioavailability of a sustained-release verapamil preparation. (1990) (10)
- α‐Methyladrenaline is a central metabolite of α‐methyldopa (1983) (9)
- Demonstration of a S-methyl metabolite of captopril in patients undergoing chronic captopril therapy. (1982) (9)
- Insulin as a pressor agent: effects of 'physiological' insulin concentrations on finger blood pressure. (1996) (9)
- New developments in alpha-adrenoreceptor drugs for the treatment of hypertension. (1982) (9)
- The N-methyl-D-aspartate (NMDA) receptor antagonist MK-801, attenuates the Bezold-Jarisch reflex in the anaesthetized rat (1987) (9)
- Comparison of Pharmacokinetics and Pharmacodynamics of Adrenoceptor Agonists and Antagonists as Antihypertensive Agents (1986) (9)
- A double-blind crossover comparison of pindolol, metoprolol, atenolol and labetalol in mild to moderate hypertension. (1979) (9)
- Clopamide: Plasma concentrations and diuretic effect in humans (1987) (9)
- Relationship of immunoassayable clonidine plasma levels to its pharmacologic action in clinical and experimental hypertension. (1983) (9)
- Tachyphylaxis to Alpha‐ and Beta‐Angiotensin in Dogs Perfused with Ringer's Solution or Blood (1968) (8)
- A Risk-Benefit Assessment of Carvedilol in the Treatment of Cardiovascular Disorders (1994) (8)
- Sites of actions of alpha 2 agonists in the brain and periphery. (1988) (8)
- Characterization of Central α-Adrenoceptors Using 3H-Clonidine and Its Derivatives (1983) (8)
- EFFECTS OF ANTIHYPERTENSIVE DRUGS ON CARDIOVASCULAR RISK FACTORS (1988) (8)
- The Expression of MTUS1/ATIP and Its Major Isoforms, ATIP1 and ATIP3, in Human Prostate Cancer (2011) (8)
- Regional Brain Concentrations of Several Putative Peptide Neurotransmitters in Normotensive and Spontaneously Hypertensive Rats: Effects of Continuous (10‐Day) Clonidine Infusion (1986) (8)
- The pharmacokinetics of captopril and captopril disulfide conjugates in uraemic patients on maintenance dialysis: Comparison with patients with normal renal function (2004) (8)
- Dynorphin(1-8) immunoreactivity in brainstem and hypothalamic nuclei of normotensive and age-matched hypertensive rat strains. (1987) (7)
- An analysis of the blood pressure response to labetalol in hypertensive patients. (1981) (7)
- Preparation, isolation and properties of [35-S] phenylthiocarbamyl angiotensin. (1966) (7)
- Endogenous and α-methylated catecholamine levels in anterior hypothalamic-preoptic and medullary nuclei in rat brain after chronic α-methyldopa administration (1979) (7)
- Steady‐State Pharmacokinetics and Pharmacodynamics of Cilazapril in the Presence and Absence of Cyclopenthiazide (1992) (7)
- Systematic errors in estimating mean blood pressure from finger blood pressure measurements. (1998) (7)
- Beta-adrenoceptor-blocking drugs: current status and the significance of partial agonist activity. (1983) (7)
- Use of dopamine and prazosin combined in the treatment of cardiogenic shock. (1980) (7)
- 'Physiological' hyperinsulinaemia increases distal artery systolic blood pressure without changing proximal blood pressure. (1997) (7)
- Altered α1-Adrenoceptor–Mediated Responses in Atria of Rats with Chronic Left Ventricular Infarction (1991) (7)
- The effect of ketanserin on cardiovascular reflexes in conscious normotensive and spontaneously hypertensive rats. (1990) (7)
- The role of noradrenaline and other transmitter hormones in the pathogenesis of hypertension. (1976) (6)
- Molecular studies of alpha‐2‐adrenoceptor and catecholamine‐insensitive imidazoline‐receptor binding sites using [3H]-rilmenidine in rat brain and kidney (1993) (6)
- Pharmacology and subcellular distribution of [3H]rilmenidine binding sites in rat brain. (1998) (6)
- Role of Tyr356(7.43) and Ser190(4.57) in antagonist binding in the rat β1-adrenergic receptor (2006) (6)
- The effect of salt intake and adrenal steroids on blood pressure in a genetic strain of hypertensive rats. (1975) (6)
- Clinical pharmacology of adrenergic-blocking drugs. (1979) (6)
- Clinical pharmacology of adrenergic-adrenoreceptor-blocking drugs. (1982) (6)
- Sympathetic activity and essential hypertension. (1973) (6)
- Synthesis, beta-adrenoceptor pharmacology and toxicology of S-(-)-1-(4-(2-ethoxyethoxy)phenoxy)-2-hydroxy-3-(2-(3,4-dimethoxyphenyl)ethylamino)propane hydrochloride, a short acting beta(1)-specific antagonist. (2002) (6)
- 6-Hydroxydopamine and excitotoxin lesions of medial prefrontal cortex fail to affect schedule-induced drinking in the rat (1986) (6)
- Inositol hexakisphosphate binding sites in rat heart and brain (1996) (6)
- Cardiac α‐Adrenoceptors Involving Positive Chronotropic Responses (1985) (6)
- Role of metabolic risk factors in cardiovascular prognosis of systemic hypertension. (1990) (6)
- Effect of α-methyldopa on dopaminergic transmission in the corpus striatum (1978) (6)
- Nature of [3H]rilmenidine binding to membranes of rat cerebral cortex. (1992) (6)
- Synthesis and β-adrenoceptor agonist properties of (±)-1-(3',4'-dihydroxyphenoxy)-3-(3",4"-dimethoxyphenyl) ethylamino-2-propanol hydrochloride, (±)-RO363.HCl, and the (2S)-(-)-isomer (1999) (5)
- Pharmacokinetic Comparison of a Slow‐Release Clonidine with a Conventional Formulation After Acute and Chronic Administration in Hypertensives (1992) (5)
- Renal and vascular actions of dopamine and their clinical significance. (1974) (5)
- Interaction between the cardiovascular effects of Clonidine and the κ‐opioid agonist U‐50,488H in the anterior hypothalamic area of the rat brain (1989) (5)
- Positive chronotropic responses in the rat heart produced by α-adrenoceptor activation (1982) (5)
- Bezold-Jarisch reflex is inhibited by excitotoxin-induced destruction of vagal primary afferent neurons. (1987) (5)
- The effect of penicillamine and related thiols on cyclophosphamide-induced cystitis and bone marrow suppression. (1984) (5)
- The influence of food on the oral bioavailability of terazosin. (1991) (5)
- Cardiac alpha-adrenoceptors: postjunctional and prejunctional. (1986) (5)
- [3H]Rilmenidine-labelled imidazoline-receptor binding sites co-localize with [3H]2-(benzofuranyl)-2-imidazoline-labelled imidazoline-receptor binding sites and monoamine oxidase-B in rabbit, but not rat, kidney. (1998) (5)
- Single-Dose and Steady-State Pharmacokinetics of Doxazosin Given in Combination with Chlorothiazide to Hypertensive Subjects (1989) (5)
- β-adrenoceptor agonists and antagonists : conformational analysis of the ethanolamine and propanolamine side-chain (1993) (5)
- β1- and β2-Adrenoceptor antagonist activity of a series of para-substituted N-isopropylphenoxypropanolamines (1999) (5)
- Computer-aided mapping of the beta-adrenoceptor. 1. Explanation for effect of para substitution on blocking activity at the beta-1-adrenoceptor. (1992) (5)
- International views of the use of calcium antagonists in the treatment of hypertension. (1985) (4)
- Comparison of β-endorphin immunoreactivity in hypothalamic and brainstem nuclei of normotensive and age-matched hypertensive rat strains (1986) (4)
- DOUBLE-BLIND COMPARISON OF OMEPRAZOLE, 10 MG VERSUS 30 MG, FOR HEALING DUODENAL-ULCERS (1986) (4)
- Pharmacokinetics and Concentration‐Effect Relationships of Bevantolol (CI‐775) in Normal Volunteers (1986) (4)
- The hypotensive action of LB 46. (1972) (4)
- Pharmacology of celiprolol (2004) (4)
- alpha- and beta-Adrenoceptor activities of norepinephrine analogues in isolated tissues of the rat. (1980) (4)
- Prediction of acute myocardial disposition of antiarrhythmic drugs. (1989) (4)
- Morning or evening dosing with low-dose omeprazole: Effects on 24-hour gastric acidity profiles in duodenal ulcer patients (1986) (4)
- Positive chronotropic responses produced by alpha-adrenoreceptors in the pithed rat. (1982) (4)
- POSITIVE CHRONOTROPIC REPONSES TO CARDIAC α1‐ADRENORECEPTOR ACTIVATION IN THE PITHED RAT (1986) (4)
- The effects of a single dose of dilevalol on [3H]-noradrenaline plasma kinetics and plasma lipoprotein cholesterol concentrations. (1990) (3)
- CoMFA analysis of the human beta(1)-adrenoceptor binding affinity of a series of phenoxypropanolamines. (2002) (3)
- Selectivity of a series of clonidine-like drugs for alpha 1 and alpha 2 adrenoceptors in rat brain. (1980) (3)
- The relationship between the vascular responses to the peptides ranatensin and angiotensin. (1971) (3)
- Evidence for dopamine receptors on GABA-releasing nerve terminals in rat nucleus accumbens [proceedings]. (1980) (3)
- THE CHARACTERISTICSOF (3H)-CLONIDINEBINDING TO AN ca-ADRENOCEPTORIN MEMBRANES FROM GUINEA-PIGKIDNEY (1979) (3)
- Rauwolfia Alkaloids (Reserpine) (1990) (3)
- Use of adrenoceptor-blocking drugs in hypertension. (1980) (3)
- Antihypertensive and noradrenaline-depleting effects of alpha-methyl-5-hydroxytryptophan in the rat. (1969) (3)
- Plasma renin, urinary sodium excretion and vascular disease. (1975) (3)
- Antibiotic-Induc ed Release ofEndotoxin inChronically Bacteriuric Patients (1991) (3)
- Interaction of angiotensin II with catecholamines in the circulation of the dog and cat. (1976) (3)
- Role of Tyr(356(7.43)) and Ser(190(4.57)) in antagonist binding in the rat beta1-adrenergic receptor. (2006) (3)
- Synthesis, β‐Adrenoceptor Pharmacology and Toxicology of S‐(‐)‐1‐(4‐(2‐ethoxyethoxy)phenoxy)‐2‐hydroxy‐3‐(2‐ (3,4‐dimethoxyphenyl)ethylamino)propane Hydrochloride, a Short Acting β1‐Specific Antagonist. (2003) (3)
- Agonist binding and activation of the rat β1-adrenergic receptor: role of Trp134 (3.28), Ser190 (4.57) and Tyr356 (7.43) (2004) (3)
- Site-directed mutagenesis of the rat beta1-adrenoceptor. Involvement of Tyr356 (7.43) in (+/-)cyanopindolol but not (+/-)[125Iodo]cyanopindolol binding. (2004) (3)
- Rapidly developing pseudohypertension after renal transplantation diagnosed by non-auscultated blood pressure measurement. (1994) (3)
- Regulatory demands for cost-benefit studies. (1990) (2)
- Alpha blockers and vasodilating beta blockers--influence on factors involved in the pathogenesis of vascular disease in patients with hypertension. (1989) (2)
- Evaluation of the predicted secondary structure of bacteriorhodopsin. Prediction of the bovine rhodopsin secondary structure and its sequence similarity with bacteriorhodopsin. (1992) (2)
- Steady state plasma [3H] noradrenaline kinetics in quadriplegic chronic spinal cord injury patients (1990) (2)
- The effects of aldosterone and angiotensin on renal function. (1966) (2)
- Positive chronotropic responses to cardiac alpha 1-adrenoreceptor activation in the pithed rat. (1986) (2)
- Immunoassay of chromogranins in tissue perfusates and plasma (1973) (2)
- O-20-6 The effects of rilmenidine on memory, attention and planning in the elderly (1996) (2)
- Cardiac alpha-adrenoceptors (1986) (2)
- Assay of brain 3,4-dihydroxyphenylethyleneglycol (DHPG) levels by high-performance liquid chromatography with electrochemical detection. Factors affecting stability during sample preparation. (1984) (2)
- P-20-5 Effects of imidazoline drugs on early response gene activity in brain, kidney and adrenal gland (1996) (2)
- Phaeochromocytoma in the Elderly: A Poorly Recognized Entity (1987) (2)
- Guanethidine and Related Compounds (1990) (2)
- The relationship between the vascular responses to the peptides angiotensin and pitressin. (1966) (2)
- Synthesis and β‐Adrenoceptor Agonist Properties of (.+‐.)‐1‐(3′,4′‐Dihydroxyphenoxy)‐3‐ (3′′,4′′‐dimethoxyphenyl)ethylamino‐2‐propanol Hydrochloride, (.+‐.)‐RO363×HCl, and the (2S)‐(‐)‐Isomer. (1999) (1)
- Studies of neurotransmitter release in the pathogenesis of hypertension. (1977) (1)
- Interrelationships of the renin angiotensin system and the sympathetic nervous system in the pathogenesis of hypertension in man-a hypothesis. (1975) (1)
- LABETALOL IN HYPERTENSION (1978) (1)
- Determinants of the extent of tolerance to glyceryl trinitrate in an isolated tissue model (1986) (1)
- Function and expression of ATIP and its variants in cardiomyoblast cell line H9c2 (2015) (1)
- The pressor response to noradrenaline and tyramine during angiotensin tachyphylaxis in the dog. (1966) (1)
- Response to “Commentary on ‘Influence of Food on the Bioavailability of Verapamil’ ” (1991) (1)
- Acute and chronic administration of alpha-methyldopa: regional levels of endogenous and alpha-methylated catecholamines in rat brain. (1978) (1)
- Characterization of central alpha-adrenoceptors using 3H-clonidine and its derivatives. (1983) (1)
- Characterization of a-Adrenoceptors in Rat and Guinea Pig Tissues using Radiolabeled Agonists and Antagonists (1980) (1)
- Pharmacokinetics of prilocaine in intravenous regional anaesthesia (2009) (1)
- P-19-41 MAO-B enzyme and I2-imidazoline receptor binding sites after excitotoxic lesions of rat hippocampus (1996) (1)
- Anticonvulsant effects of clonidine on pentylenetetrazol (PTZ)-induced convulsions in rats (1982) (1)
- Antibiotic-Induced Release of Endotoxin in Chronically Bacteriuric Patients (1992) (1)
- Alpha 2-adrenoceptor and catecholamine-insensitive binding sites for [3H]rilmenidine in membranes from rat cerebral cortex. (1992) (1)
- Quality of life--treatment of hypertension. The role of indapamide. (1989) (0)
- Effect of alpha-methyldopa on dopaminergic transmission in the corpus striatum. (1978) (0)
- Effect of acute alpha-methyldopa administration on catecholamine levels in anterior hypothalamic-preoptic and medullary nuclei in rat brain [proceedings]. (1978) (0)
- Enhancement of pentylenetetrazol (PTZ) induced convulsions following clonidine withdrawal in rats (1982) (0)
- 1-phenoxy-2-hydroxy-3-aminopropanderivater, pharmaceutical composition containing the derivatives and the use of the derivatives (1983) (0)
- -635S(U)9myo-inositol 1,4,5-trisphosphorothiate autoradiography in rat myocardium: Effect of infarction on IP3-sensitive binding (1992) (0)
- The combined use of L-alpha-methyldopa hydrazine and methyldopa in the treatment of hypertension. (1978) (0)
- FORMATION OF α-METHYLNOREPINEPHRINE IN RAT BRAIN STEM AND NUCLEUS TRACTUS SOLITARIUS AFTER ACUTE INJECTION OF α-METHYLDOPA (1979) (0)
- alpha-Methyladrenaline is a central metabolite of alpha-methyldopa. (1983) (0)
- Is hyperinsulinaemia during withdrawal of ethanol due to an increase in secretion of insulin or a decrease in clearance of insulin? (1998) (0)
- Relevance of pharmacokinetic differences between ACE inhibitors and their role in the treatment of hypertension. (1993) (0)
- Adrenaline depletion in the hypothalamus of the rat after chronic alpha-methyldopa. (1981) (0)
- Pharmac . ( 1975 ) , 2 , 159-164 P-ADRENERGIC RECEPTOR BLOCKING DRUGS , HYPERTENSION AND PLASMA RENIN (2006) (0)
- Pharmac . ( 1979 ) , 65 , 663-670 THE CHARACTERISTICS OF [ 3 H ]-CLONIDINE BINDING TO AN ca-ADRENOCEPTOR IN MEMBRANES FROM GUINEA-PIG KIDNEY (2006) (0)
- Determinants of acute drug uptake into the myocardium in man (1986) (0)
- Ketanserin-induced modulation of cardiovascular reflex function is reduced in conscious spontaneously hypertensive rats after chemical vagal deafferentation (1990) (0)
- The Mitogen-activated Protein Kinase Kinase 3 (0)
- 3-aminopropyloxyphenylabkoemmlinge, manufacturing and arzneitmittel they contain. (1986) (0)
- β1‐ and β2‐Adrenoceptor Antagonist Activity of a Series of para‐Substituted N‐Isopropylphenoxypropanolamines. (2000) (0)
- IncreaseIn PlasmaCholesterolon Subjects'Standing Correlateswith the IncreaseIn PlasmaNoreplnephrlne, (1988) (0)
- Characterization of binding sites for the novel antihypeitensive drug, rilmenidine in rat brain membranes (1990) (0)
- The drug treatment of hypertension--the place of calcium antagonists. (1985) (0)
- Pharmacokinetic studies of sodium valproate following acute and chronic administration in epileptic patients (1979) (0)
- ANGIOTENSIN AND RENAL EXCRETION (1966) (0)
- Agonist binding and activation of the rat beta(1)-adrenergic receptor: role of Trp(134(3.28)), Ser(190(4.57)) and Tyr(356(7.43)). (2004) (0)
- Interaction of clonidine metabolites with an α-adreno receptor in rat brain membranes (1979) (0)
- Turnover of Catecholamines in Experimental Hypertension (1970) (0)
- α-and β-Adrenoceptor Activities of Norepinephrine Analogues in Isolated Tissues of the Rat (1980) (0)
- Relationship between α-adrenoceptor selectivity and anticonvulsant activity after chronic clonidine-like drugs in rats (1982) (0)
- 3-aminopropoxyphenylderivater, process for their preparation and to pharmaceutical preparations containing these derivatives (1985) (0)
- Age related changes in noradrenaline, noradrenaline turnover and adrenaline in brainstem nuclei of wistar kyoto and spontaneously hypertensive rats (1988) (0)
- Role of central α2 adrenoceptors in control of pentylenetetrazol (PTZ) induced convulsions in rats (1982) (0)
- PLASMA CATECHOLAMINE A N D DOPAMINE P-HYDROXYLASE AMOUNTS (2012) (0)
- brain. Effects of methyldopa metabolites on amine transmitters and adrenergic receptors in rat (2013) (0)
- 1379 – DISPLACEMENT OF 3H CLONIDINE BINDING BY CLONIDINE ANALOGUES IN MEMBRANES FROM RAT CEREBRAL CORTEX (1978) (0)
- Endogenous and alpha-methylated catecholamine levels in anterior hypothalamic-preoptic and medullary nuclei in rat brain after chronic alpha-methyldopa administration. (1979) (0)
- Theinfluence offoodontheoral bioavailability ofterazosin (1991) (0)
- Labeling of α2-adrenoceptors in rat cerebral cortex with 3H-guanfacine (1981) (0)
- 239 – MONOAMINE OXIDASE DEFICIENCY IN PHAEOCHROMOCYTOMAS: AN EXPLANATION FOR THE INCREASED RELEASE OF CATECHOLAMINES FROM THESE TUMOURS (1977) (0)
- Localization and modulation of Galanin mRNA in rat brain: effect of reserpine treatment on locus coendeus neurones (1990) (0)
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