Woon-ki Paik

Woon-ki Paik's AcademicInfluence.com Rankings

Woon-ki Paik

Biology

#12777

World Rank

#16276

Historical Rank

Molecular Biology

#2102

World Rank

#2134

Historical Rank

Biochemistry

#2210

World Rank

#2355

Historical Rank

biology Degrees

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Biology

Woon-ki Paik's Degrees

PhD Biochemistry Seoul National University
Masters Biochemistry Seoul National University
Bachelors Biochemistry Seoul National University

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Woon-ki Paik's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

PRMT1 Is the Predominant Type I Protein Arginine Methyltransferase in Mammalian Cells* (2000) (422)
Historical review: the field of protein methylation. (2007) (234)
Protein methylase I. Purification and properties of the enzyme. (1968) (190)
Enzymatic methylation of protein fractions from calf thymus nuclei. (1967) (151)
Studies of histone methylation during the HeLa S-3 cell cycle. (1972) (135)
Nonenzymatic acetylation of histones with acetyl-CoA. (1970) (124)
Identification of N(G)-methylarginine residues in human heterogeneous RNP protein A1: Phe/Gly-Gly-Gly-Arg-Gly-Gly-Gly/Phe is a preferred recognition motif. (1997) (119)
Purification and molecular identification of two protein methylases I from calf brain. Myelin basic protein- and histone-specific enzyme. (1988) (117)
Methylation of O6‐methylguanine‐DNA methyltransferase gene is associated significantly with K‐ras mutation, lymph node invasion, tumor staging, and disease free survival in patients with gastric carcinoma (2001) (107)
The relationship of histone phosphorylation to deoxyribonucleci acid replication and mitosis during the HeLa S-3 cell cycle. (1973) (96)
Protein methylation: chemical, enzymological, and biological significance. (1975) (96)
Enzymatic demethylation of calf thymus histones. (1973) (89)
E-N-dimethyllysine in histones (1967) (87)
A rapid method for the purification of S-adenosylmethionine: protein-carboxyl O-methyltransferase by affinity chromatography. (1978) (85)
Structural specificity of substrate for S-adenosylmethionine:protein arginine N-methyltransferases. (1995) (83)
S-adenosylmethionine: protein-arginine methyltransferase. Purification and mechanism of the enzyme. (1977) (81)
Solubilization and partial purification of protein methylase 3 from calf thymus nuclei. (1970) (79)
Studies on the origin of epsilon-N-methyl-L-lysine in protein. (1965) (79)
Biological methylation of myelin basic protein: enzymology and biological significance. (1997) (76)
Induction of growth inhibition of 293 cells by downregulation of the cyclin E and cyclin‐dependent kinase 4 proteins due to overexpression of TIS21 (1998) (75)
Effect of enzymic methylation of heterogeneous ribonucleoprotein particle A1 on its nucleic-acid binding and controlled proteolysis. (1994) (68)
Biochemical Studies on Amphibian Metamorphosis : I. The effect of thyroxine on protein synthesis in the tadpole (1960) (66)
Methylation of O(6)-methylguanine-DNA methyltransferase gene is associated significantly with K-ras mutation, lymph node invasion, tumor staging, and disease free survival in patients with gastric carcinoma. (2001) (65)
Enzymatic methylation of recombinant heterogeneous nuclear RNP protein A1. Dual substrate specificity for S-adenosylmethionine:histone-arginine N-methyltransferase. (1994) (62)
Ammonia intoxication in rats: protection by N-carbamoyl-L-glutamate plus L-arginine. (1972) (59)
Epsilon-alkyllysinase. New assay method, purification, and biological significance. (1974) (54)
Studies on compartmentation of S-adenosyl-L-methionine in Saccharomyces cerevisiae and isolated rat hepatocytes. (1983) (52)
Determination of methylated amino acids in human serum by high-performance liquid chromatography. (1988) (52)
Enzymatic methylation of histones. (1969) (50)
EPSILON-ALKYLLYSINASE. PURIFICATION AND PROPERTIES OF THE ENZYME. (1964) (47)
Multimerization of expressed protein-arginine methyltransferases during the growth and differentiation of rat liver. (2005) (45)
Purification and characterization of S-adenosylmethionine-protein-arginine N-methyltransferase from rat liver. (1994) (43)
Cytochrome c-specific protein-lysine methyltransferase from Neurospora crassa. Purification, characterization, and substrate requirements. (1978) (43)
Methylation of Ribosomal Proteins in Escherichia coli (1974) (43)
Studies on substrate specificity of S-adenosylmethionine: protein-carboxyl methyltransferase from calf brain. (1980) (42)
The synthesis of carbamyl phosphate synthetase in thyroxin-treated tadpoles. (1961) (41)
ϵ-Lysine acylase (1957) (38)
Studies on cytochrome c methylation in yeast. (1979) (38)
ω-N-Methylarginine in Protein (1970) (38)
Protein methylases in hepatomas. (1972) (37)
Enzymatic methylation of in vitro synthesized apocytochrome c enhances its transport into mitochondria. (1987) (36)
STUDIES ON THE NATURAL SUBSTRATE FOR PROTEIN METHYLASE II IN MAMMALIAN BRAIN AND BLOOD (1975) (35)
Effect of methylation on susceptibility of protein to proteolytic enzymes. (1972) (34)
Protein methylation. (2020) (33)
The periodic synthesis of S-adenosylmethionine: protein methyltransferases during the HeLa S-3 cell cycle. (1973) (32)
Protein methylation during the development of rat brain. (1972) (32)
Non‐enzymatic methylation of proteins with S‐adenosyl‐L‐methionine (1975) (30)
PROTEIN METHYLATION IN RAT BRAIN IN VITRO (1969) (30)
In vivo carboxyl methylation of human eruthrocyte membrane proteins. (1980) (30)
Protein methylases during the development of rat brain. (1973) (29)
ω-N-methylarginine in histones (1970) (28)
PURIFICATION AND PROPERTIES OF HOG KIDNEY ϵ-LYSINE ACYLASE (1963) (28)
Urinary excretion of N G-dimethylarginines in multiple sclerosis patients: preliminary observations (1995) (28)
Studies on the kinetic mechanism of S-adenosylmethionine: protein O-methyltransferase of calf thymus. (1975) (27)
Studies on myelin-basic-protein methylation during mouse brain development. (1986) (27)
Purification and characterization of enzymes from Euglena gracilis that methylate methionine and arginine residues of cytochrome c. (1985) (25)
Studies on NG-methylarginine derivatives in myelin basic protein from developing and mutant mouse brain. (1992) (24)
Age-dependency of various protein methylases. (1971) (24)
Histone methylation during hepatic regeneration in rat. (1972) (24)
Enzymatic methylation of heterogeneous nuclear ribonucleoprotein in isolated liver nuclei. (1992) (23)
Natural inhibitor for protein methylase. II. (1971) (23)
Studies on myelin basic protein-specific protein methylase I in various dysmyelinating mutant mice. (1984) (23)
Substrate specificity for myelin basic protein-specific protein methylase I. (1990) (22)
Enzymic methylation of myelin basic protein in myelin. (1991) (22)
New assay method for protein methylase II activity suitable for trichloroacetic acid soluble substrate, based on distillation of methanol. (1971) (22)
In vivo studies on yeast cytochrome c methylation in relation to protein synthesis. (1980) (22)
A comparison of kinetic parameters of polypeptide substrates for protein methylase II. (1976) (22)
Biochemical studies on amphibian metamorphosis. III. Metabolism of nucleic acids and nucleotides in tadpole liver during thyroxine-induced metamorphosis. (1961) (21)
PH-SUBSTRATE RELATIONSHIP OF L-AMINO ACID OXIDASES FROM SNAKE VENOM AND RAT KIDNEY. (1965) (21)
Carnitine biosynthesis via protein methylation (1977) (21)
Histone-specific protein-arginine methyltransferase from wheat germ. (1982) (21)
Effect of methylation on the stability of cytochrome c of Saccharomyces cerevisiae in vivo. (1981) (21)
Selective methyl esterification of erythrocyte membrane proteins by protein methylase II. (1978) (20)
Cytochrome c specific methylase from wheat germ. (1982) (20)
Enzymatic trimethylation of residue-72 lysine in cytochrome c. Effect on the total structure. (1980) (20)
Recent advances in protein methylation: Enzymatic methylation of nucleic acid binding proteins (1998) (19)
Enzymatic methylation and demethylation of protein-bound lysine residues. (1984) (19)
Studies on S-adenosylmethionine:protein-carboxyl methyltransferase in the hypothalamo-neurohypophysial complex in organ culture. (1975) (18)
Cytochrome c-specific protein methylase III from Neurospora crassa. (1977) (18)
Enzymic methylation of arginyl residues in -gly-arg-gly- peptides. (2000) (18)
Cytochrome c methylation. (1989) (17)
Binding of carcinogenic aromatic amine to rat liver nuclear acidic proteins in vivo. (1971) (17)
Methylesters ofl-Arginine andN-Nitro-l-arginine Induce Nitric Oxide Synthase inStaphylococcus aureus (1998) (17)
S-adenosylmethionine:protein methyltransferases in hepatomas. (1975) (17)
Enzymology of protein methylation. (1986) (16)
Reduced erythrocyte membrane protein methylation in sickle cell anemia. (1981) (16)
THE ACTION OF ULTRAVIOLET RADIATION ON YEAST CATALASE (1956) (16)
Effect of enzymatic methylation of yeast iso-1-cytochrome c on its isoelectric point. (1988) (16)
Enzymic synthesis of ?-N-acetyl--lysine (1964) (15)
Two histone H1-specific protein-lysine N-methyltransferases from Euglena gracilis. Purification and characterization. (1985) (15)
Studies on naturally occurring proteinous inhibitor for transmethylation reactions. (1986) (15)
Microsome-dependent methylation of erythrocyte proteins by dimethylnitrosamine. (1981) (15)
Urea synthesis in Novikoff and Morris hepatomas. (1977) (15)
Differential expression of O 6-methylguanine-DNA methyltransferase during diethylnitrosamine-induced carcinogenesis and liver regeneration in Sprague-Dawley male rats (1999) (14)
Enzymatic methylation of recombinant TIS21 protein‐arginine residues (1998) (14)
Deacetylation of α-keto-ε-acetamidocaproic acid by ε-lysine acylase (1962) (14)
Alkylation of protein by methyl methanesulfonate and 1-methyl-1-nitrosourea in vitro. (1984) (13)
Cytochrome c methylation. (1989) (13)
Studies on histone acetylation during thyroxine-induced amphibian metamorphosis. (1972) (13)
Purification and characterization of protein methylase I (S-adenosylmethionine: protein-arginine methyltransferase; EC 2.1.1.23) from calf brain. (1978) (12)
Carbamyl phosphate synthetases in rat liver neoplasms. (1975) (12)
Hydrolytic degradation of purine derivatives to glycine. (1962) (12)
Identification of the S-adenosyl-L-methionine binding site of protein-carboxyl O-methyltransferase using 8-azido-S-adenosyl-L-methionine. (1993) (12)
Simple separation of adenine and adenosyl-sulfur compounds by high-performance liquid chromatography. (1983) (12)
Measurement of isoelectric point of S‐adenosyl‐L‐methionine and its metabolic products by an isoelectric focusing technique (1983) (12)
The tRNA methylases during thyroxine-induced differentiation in bull frog tadpoles. (1971) (11)
A peptide inhibitor for S-adenosyl-L-methionine-dependent transmethylation reactions. Purification and characterization. (1993) (11)
Studies on the distribution of O6-methylguanine-DNA methyltransferase in rat. (1986) (11)
Identification of highly methylated arginine residues in an endogenous 20-kDa polypeptide in cancer cells. (1999) (11)
Enzymatic hydrolysis of histones in rat kidney microsomes. (1970) (11)
The activity of lactate dehydrogenase isozymes during thyroxine-induced tadpole metamorphosis. (1966) (10)
Metabolism of NG-monomethyl-L-arginine. (1983) (10)
Biochemical studies on amphibian metamorphosis. II. The effect of thiouracil on thyroxine-stimulated protein synthesis in tadpole liver. (1961) (10)
[24] A simple analysis of methylated proteins (1984) (10)
Effect of methyl substitution on protein tertiary structure. (1992) (10)
Cytochrome c methylation: enzymology and biologic significance. (1980) (10)
Phosphorylation of methylated-DNA-protein-cysteine S-methyltransferase at serine-204 significantly increases its resistance to proteolytic digestion. (2000) (9)
Myelin basic protein inhibits histone-specific protein methylase I. (1986) (9)
Purification and assay of protein methylase II (S-adenosylmethionine:protein-carboxyl methyltransferase; EC 2.1.1.24). (1978) (9)
Increased methylation of endogenous 20-kDa protein in HIT beta-cell during insulin secretion. (2003) (9)
Studies on the stability of L-amino-acid oxidase of snake venom. (1967) (9)
Studies on in vitro S-methylation of naturally occurring thiol compounds with N-methyl-N-nitrosourea and methyl methanesulfonate. (1987) (9)
Studies of the identity of the unknown in protein hydrolysates. (1980) (8)
Address of the Editor-in-Chief (1996) (8)
Heterogeneous nuclear RNP protein A1‐arginine methylation during HCT‐48 cell cycle (1997) (8)
Enzymatic trimethylation of lysine-72 in cytochrome c. (1983) (8)
A comparative study of ?-lysine acylase (1963) (8)
Protein methylase III of rat kidney during the early development (1973) (8)
HPLC analysis of methylated amino acids: Methylated amino acids on HPLC (1986) (7)
Preparation of radioactive ε-N-methylated lysines not involving elaborate organic synthesis (1978) (7)
Methylesters of L-arginine and N-nitro-L-arginine induce nitric oxide synthase in Staphylococcus aureus. (1998) (7)
Myelin basic protein‐specific protein methylase I activity in shiverer mutant mouse brain (1986) (7)
Autoradiographic studies on metabolism of DNA during thyroxine-induced tadpole metamorphosis. (1971) (7)
Metabolism of NG-monomethyl-L-arginine: formation of NG-methylagmatine by Escherichia coli preparation. (1981) (7)
Pronase-based assay method for O6-methylguanine-DNA methyltransferase. (1996) (7)
Current status of protein methylation in carcinogenesis. (1991) (7)
Studies on reaction of formaldehyde with naturally occurring thiol compounds and ascorbic acid (1988) (7)
Comparative studies on S-adenosyl-l-methionine binding sites of protein N-methyltransferases, using 8-azido-S-adenosyl-l-methionine as photoaffinity probe (1993) (6)
Enzymology of Protein Methylation: Recent Development (1986) (6)
Omega-N-methylarginine in protein. (1970) (6)
Thyroxine-binding proteins in liver and tail of Rana catebeiana undergoing metamorphosis. (1976) (6)
N-carbamoyl-L-glutamate plus L-arginine can protect ammonia intoxication in rats with reduced functional liver mass. (1998) (6)
An enzyme-linked immunosorbent assay for myelin basic protein-specific protein methylase I (1991) (6)
Protein Methylation: Perspectives in Central Nervous System (1979) (6)
Enzymatic modification of nuclear proteins during neoplastic growth. (1977) (5)
Colorimetric Differentiation of α- and ɛ-N-substituted Lysine Derivatives (1964) (5)
On the metabolism of epsilon-N-methyl-L-lysine by rat-kidney homogenate. (1963) (5)
Effect of enzymatic methylation of proteins on their isoelectric points (1989) (5)
Effect of modification on inhibitory amino acids on arginase activity. (1978) (5)
Mixture of N-carbamoyl-L-glutamate plus L-arginine can protect rats with liver cirrhosis from acute ammonia intoxication. (2001) (5)
A new HPLC analytical method for o-hydroxyhippuric acid in uremic serum. (1986) (5)
Labile protein-methyl ester: Comparison between chemically and enzymatically synthesized (1976) (5)
In vivo andin vitro methylation of lysine residues ofEuglena gracilis histone H1 (1992) (4)
Site specificity of histone H4 methylation by wheat germ protein-arginine N-methyltransferase. (1986) (4)
The methylation and demethylation of protein lysine residues. (1978) (4)
Biochemical Studies on Amphibian Metamorphosis (1960) (4)
Enzymatic methylation of arginine residue in myelin basic protein. (1988) (4)
Comparison of the acetylation of proteins and nucleic acids. (1970) (4)
Studies on High Mobility Group Chromosomal Proteins in Novikoff Hepatoma (1981) (4)
NG-Methylarginines: Biosynthesis, biochemical function and metabolism (1993) (4)
Protein methylation: cytochrome c methylation as a model system. (1980) (4)
Identification of Protein-ArginineN-Methyltransferase as 10-Formyltetrahydrofolate Dehydrogenase* (1998) (4)
Effect of enzymatic methylation of apocytochrome c on holocytochrome c formation and proteolysis. (1989) (4)
S-adenosylmethionine: protein (arginine) N-methyltransferase (protein methylase I) (wheat germ). (1984) (4)
Effect of glutathione on ribonuclease. (1968) (4)
The effect of thalidomide and its derivatives on thyroxine-induced metamorphosis of tadpole. (1965) (3)
Effect of enzymatic methylation of cytochrome c on its function and synthesis. (1990) (3)
A simple analysis of methylated proteins. (1984) (3)
Protein Methylation and Interaction with the Antiproliferative Gene, BTG2/TIS21/Pc3 (2014) (3)
Replacement of L-ornithine with L-lysine for urea cycle enzymes (1977) (3)
Liver tryptophan pyrrolase activity during thyrosine-induced metamorphosis of Rana catesbeiana. (1968) (3)
Effect of S-Adenosyl-L-Methionine and S-Adenosyl-L-Homocysteine Derivatives on Protein Methylation (1980) (3)
An endogenous proteinacious inhibitor in porcine liver for S-adenosyl-L-methionine dependent methylation reactions: identification as oligosaccharide-linked acyl carrier protein. (2000) (3)
Determination of N-methylurea: comparison of two colorimetric methods using diacetyl monoxime or alpha-isonitropropiophenone. (1982) (3)
δ-N-[methyl-14C]arginine: A simplified preparation (1980) (3)
Effect of enzymatic methylation on the import of in vitro synthesized apocytochrome C into mitochondria. (1988) (3)
Histone binding to isolated rat liver nuclei. (1987) (3)
Methylation of nuclear proteins of Novikoff hepatoma. (1980) (2)
Effect of Age and Nephrectomy on ε-Lysine Acylase of Rat Kidney (1966) (2)
Effect of endocrine glands on the protection of rat from ammonia intoxication. (1974) (2)
Effect of developmental stage on arginase and urea production in the liver of rat. (1984) (2)
The alteration of intracellular enzymes. IV. Kinetics of catalase alteration induced by chemical agents. (1956) (2)
ENZYMIC SYNTHESIS OF EPSILON-N-ACETYL-L-LYSINE. (1964) (2)
Purification and properties of protein methylaase II. (1970) (2)
Preparation of Ng-Monoethyl-L-arginine. (1984) (2)
Endogenous proteinaceous inhibitor for protein methylation reactions (1987) (1)
An endogenous proteinacious inhibitor forS-adenosyl-L-methionine-dependent transmethylation reactions; Identification ofS-adenosylhomocysteine as an integral part (1999) (1)
A convenient synthesis of NG‐mono[14C‐methyl]‐L‐arginine (1981) (1)
Protein Methylases in ' (1)
Site-specificity of histone H1 methylation by two H1-specific protein-lysine N-methyltransferases from Euglena gracilis. (1989) (1)
Studies on protein methyltransferase in human cerebrospinal fluid (2008) (1)
Induction of thermal and chemical stability of O6-methylguanine-DNA methyltransferase by Ca2+. (2002) (1)
ENZYMATIC DEMETHYLATION OF CYTOCHROME C IN YEAST (1990) (1)
Omega-N-methylarginine in histones. (1970) (1)
Interrelationship between nuclear histone binding and cell proliferation. (1988) (1)
Effect of hydrocortisone on ammonia intoxication in the adrenalectomized rat. (1977) (1)
Chapter 19. Histone Hydrolase (1978) (1)
Identification of N(G)-methylarginine residues in heterogenous nuclear RNP protein A1 (1997) (1)
Biological function and mechanism of cytochrome c methylation (1982) (0)
A COMPARATIVE STUDY OF EPSILON-LYSINE ACYLASE. (1963) (0)
Urea Synthesis in Novikoff and Morris Hepatomas1 (2006) (0)
Purification and characterization of protein methylase II from Helicobacter pylori. (2001) (0)
Urea Synthesisin Novikoffand Morris Hepatomas1 (1977) (0)
delta-N-[methyl-14C]Arginine: a simplified preparation. (1980) (0)
A factor which counteracts the stabilizing activity of acetate ion on ophioxidase at alkaline pH (1975) (0)
Synthesis of NG-monomethylagmatine, a decarboxylation product of NG-monomethyl-L-arginine. (1987) (0)
Inhibitory Action of Histone and Polylysine on Urea Synthesis in Isolated Rat Hepatocyes (1985) (0)
Purification and properties of hog kidney epsilon-lysine acylase. (1963) (0)
epsilon-lysine acylase. (1957) (0)
Two Histone H 1-specific Protein-Lysine N-Methyltransferases from Euglena gracilis PURIFICATION (2001) (0)
CytochromeC methylation: Current knowledge of its biological significance (1988) (0)
Colorimetric determination of ϵ-N-methyl-l-lysine (1965) (0)
Urea Synthesis in Isolated Rabbit Kidney Cells (1984) (0)
Histone hydrolase. (1978) (0)
Effect of age and nephrectomy on epsilon-lysine acylase of rat kidney. (1966) (0)
Synthesis and Characterization of N-Methylamidinoglycine : an Isomer of Creatine (1985) (0)
Histone hydrolase in tadpole liver (1971) (0)
Fractionation of enzymatically methylated acid-insoluble proteins from thymus nuclei (1986) (0)
Studies on unknown methylated compounds of non-histone nuclear protein (1985) (0)
COLORIMETRIC DIFFERENTIATION OF ALPHA- AND EPSILON-N-SUBSTITUTED LYSINE DERIVATIVES. (1964) (0)
tS-Adenosylmethionine Â¡Protein Methyltransferases in Hepatomas1 (1975) (0)
Analysis of Modified Amino Acids (2018) (0)
ReducedS-adenosylmethionine: Protein-lysineN-methyltransferase activity (protein methylase III) in shiverer mutant mouse brain (1987) (0)
Changes in Histone Hydrolase Activity of Tadpole Liver and Tail During Thyroxine-Induced Metamorphosis (1980) (0)
Derivatives on Protein Methylation (1980) (0)
Deacetylation of alpha-keto-epsilon-acetamidocaproic acid by epsilon-lysine acylase. (1962) (0)
Protein methylase 3 of rat kidney during the early development. (1973) (0)
Preparation of radioactive epsilon-N-methylated lysines not involving elaborate organic synthesis. (1978) (0)
Purification and Properties of Protein Methylase (2003) (0)

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Published Works

What Schools Are Affiliated With Woon-ki Paik?

Woon-ki Paik's AcademicInfluence.com Rankings