Wayne Levin
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Chemistry Biology
Wayne Levin's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Chemistry University of California, Berkeley
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(Suggest an Edit or Addition)Wayne Levin's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- An improved staining procedure for the detection of the peroxidase activity of cytochrome P-450 on sodium dodecyl sulfate polyacrylamide gels. (1976) (1003)
- Separation and characterization of highly purified forms of liver microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls, phenobarbital, and 3-methylcholanthrene. (1979) (508)
- Purification and characterization of hepatic microsomal cytochrome P-450. (1990) (377)
- Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides in newborn mice: exceptional activity of (+)-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene. (1978) (340)
- PCBs: structure–function relationships and mechanism of action (1985) (329)
- Induction of two immunochemically related rat liver cytochrome P-450 isozymes, cytochromes P-450c and P-450d, by structurally diverse xenobiotics. (1983) (321)
- Estrogenic action of DDT and its analogs. (1969) (321)
- Regio- and stereoselective metabolism of two C19 steroids by five highly purified and reconstituted rat hepatic cytochrome P-450 isozymes. (1983) (317)
- Studies on the induction of CO-binding pigments in liver microsomes by phenobarbital and 3-methylcholanthrene. (1967) (311)
- Characterization of a major form of rat hepatic microsomal cytochrome P-450 induced by isoniazid. (1985) (309)
- Metabolism of benzo(a)pyrene and benzo (a)pyrene derivatives to mutagenic products by highly purified hepatic microsomal enzymes. (1976) (306)
- Immunochemical quantitation of cytochrome P-450 isozymes and epoxide hydrolase in liver microsomes from polychlorinated or polybrominated biphenyl-treated rats. A study of structure-activity relationships. (1983) (289)
- Marked differences in the skin tumor-initiating activities of the optical enantiomers of the diastereomeric benzo(a)pyrene 7,8-diol-9,10-epoxides. (1979) (273)
- Binding of benzo[a]pyrene 7,8-diol-9,10-epoxides to DNA, RNA, and protein of mouse skin occurs with high stereoselectivity. (1978) (272)
- Characterization of three highly purified cytochromes P-450 from hepatic microsomes of adult male rats. (1984) (263)
- Regulation of three forms of cytochrome P-450 and epoxide hydrolase in rat liver microsomes. Effects of age, sex, and induction. (1981) (262)
- Metabolism of benzo[a]pyrene. VI. Stereoselective metabolism of benzo[a]pyrene and benzo[a]pyrene 7,8-dihydrodiol to diol epoxides. (1977) (245)
- Hepatic microsomal cytochrome P-450 from rats treated with isosafrole. Purification and characterization of four enzymic forms. (1980) (239)
- Partial purification of cytochromes P-450 and P-448 from rat liver microsomes. (1972) (238)
- Multiple forms of rat liver cytochrome P-450. Immunochemical evidence with antibody against cytochrome P-448. (1976) (237)
- Purification, characterization and regulation of five rat hepatic microsomal cytochrome P-450 isozymes. (1982) (236)
- Mutagenicity and cytotoxicity of benzo(a)pyrene benzo-ring epoxides. (1976) (232)
- Lipid peroxidation and the degradation of cytochrome P-450 heme. (1973) (207)
- Regulation of cytochrome P-450j, a high-affinity N-nitrosodimethylamine demethylase, in rat hepatic microsomes. (1987) (206)
- Tumorigenicity studies with diol-epoxides of benzo(a)pyrene which indicate that (+/-)-trans-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene is an ultimate carcinogen in newborn mice. (1978) (204)
- High mutagenicity and toxicity of a diol epoxide derived from benzo(a)pyrene. (1976) (198)
- Effects of inducers and epoxide hydrase on the metabolism of benzo(a)pyrene by liver microsomes and a reconstituted system: analysis by high pressure liquid chromatography. (1974) (197)
- The resolution and reconstitution of the liver microsomal hydroxylation system. (1974) (196)
- Benzo[a]pyrene 7,8-dihydrodiol is more carcinogenic than benzo[a]pyrene in newborn mice (1977) (196)
- Metabolism of benzo[a]pyrene: conversion of (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene to highly mutagenic 7,8-diol-9,10-epoxides. (1976) (190)
- Purification of characterization of a minor form of hepatic microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls. (1982) (182)
- Characterization of ethanol-inducible human liver N-nitrosodimethylamine demethylase. (1986) (180)
- Evidence that isoniazid and ethanol induce the same microsomal cytochrome P-450 in rat liver, an isozyme homologous to rabbit liver cytochrome P-450 isozyme 3a. (1986) (168)
- Mutagenicity and cytotoxicity of benzo(a)pyrene arene oxides, phenols, quinones, and dihydrodiols in bacterial and mammalian cells. (1976) (166)
- Differences in mutagenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides. (1977) (160)
- Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds, and endogenous substrates. IX. The formation of a 455-nm metabolite-cytochrome P-450 complex. (1971) (158)
- A simple, non-chromatographic purification procedure for monoclonal antibodies. Isolation of monoclonal antibodies against cytochrome P450 isozymes. (1987) (156)
- Metabolism of drugs and carcinogens by human liver enzymes. (1966) (153)
- Metabolism of benzo[a]pyrene. Effect of substrate concentration and 3-methylcholanthrene pretreatment on hepatic metabolism by microsomes from rats and mice. (1975) (145)
- (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo (a)pyrene: a potent skin carcinogen when applied topically to mice. (1976) (140)
- Carcinogenicity of benzo[a]pyrene 4,5-, 7,8-, and 9,10-oxides on mouse skin. (1976) (137)
- Preparation of monospecific antibodies against two forms of rat liver cytochrome P-450 and quantitation of these antigens in microsomes. (1979) (132)
- Effect of halogenated hydrocarbon insecticides on the metabolism and uterotropic action of estrogens in rats and mice. (1971) (126)
- Multiple forms of cytochrome P-450 in phenobarbital- and 3-methylcholanthrene-treated rats. Separation and spectral properties. (1975) (124)
- Liver microsomal expoxide hydrase. Solubilization, purification, and characterization. (1975) (124)
- Immunochemical evidence for six forms of rat liver cytochrome P450 obtained using antibodies against purified rat liver cytochromes P450 and P448. (1976) (121)
- Preparation of partially purified, lipid-depleted cytochrome P-450 and reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase from rat liver microsomes. (1974) (120)
- Oxidative metabolism of polycyclic aromatic hydrocarbons to ultimate carcinogens. (1982) (116)
- Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds, and endogenous substrates. VI. Different substrate specificities of the cytochrome P450 fractions from control and phenobarbital-treated rats. (1973) (110)
- Identification of a human liver cytochrome P-450 homologous to the major isosafrole-inducible cytochrome P-450 in the rat. (1986) (108)
- Amino acid compositions and partial amino acid sequences of three highly purified forms of liver microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls, phenobarbital, or 3-methylcholanthrene. (1979) (108)
- Marked differences in the tumor-initiating activity of optically pure (+)- and (-)-trans-7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene on mouse skin. (1977) (108)
- Purification and characterization of ethanol-inducible human hepatic cytochrome P-450HLj. (1987) (107)
- Regulation of two members of the steroid-inducible cytochrome P450 subfamily (3A) in rats. (1993) (107)
- Mutagenicity of metabolically activated benzo[a]anthracene 3,4-dihydrodiol: evidence for bay region activation of carcinogenic polycyclic hydrocarbons. (1976) (107)
- Hepatic cytochrome P-450j induction in the spontaneously diabetic BB rat. (1988) (106)
- Interleukin‐1β induces cytosolic phospholipase a2 and prostaglandin h synthase in rheumatoid synovial fibroblasts (1994) (105)
- Induction of Benzo[α]pyrene Hydroxylase in Human Skin (1972) (104)
- Evidence that benzo(a)anthracene 3,4-diol-1,2-epoxide is an ultimate carcinogen on mouse skin. (1978) (104)
- N-demethylation of N-nitrosodimethylamine catalyzed by purified rat hepatic microsomal cytochrome P-450: isozyme specificity and role of cytochrome b5. (1986) (104)
- Regioselective progesterone hydroxylation catalyzed by eleven rat hepatic cytochrome P-450 isozymes. (1987) (101)
- Role of cytochrome b5 in hydroxylation by a reconstituted cytochrome P-450-containing system. (1974) (100)
- Metabolism of chrysene and phenanthrene to bay-region diol epoxides by rat liver enzymes. (1981) (99)
- Inhibitory effect of carbon monoxide on the hydroxylation of testosterone by rat liver microsomes. (1968) (98)
- Comparison of the O‐dealkylation of 7‐ethoxycoumarin and the hydroxylation of benzo [a] pyrene in human placenta (1974) (96)
- Mutagenicity and cytotoxicity of benz[alpha]anthracene diol epoxides and tetrahydro-epoxides: exceptional activity of the bay region 1,2-epoxides. (1977) (96)
- Age- and sex-related expression of cytochromes p450f and P450g in rat liver. (1986) (96)
- 6-Methyl-1,3,8-trichlorodibenzofuran as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist: inhibition of the induction of rat cytochrome P-450 isozymes and related monooxygenase activities. (1988) (95)
- Rat liver cytochrome P-450b, P-420b, and P-420c are degraded to biliverdin by heme oxygenase. (1988) (94)
- Multiplicity strain differences, and topology of phenobarbital-induced cytochromes P-450 in rat liver microsomes. (1982) (93)
- Immunochemical relatedness of rat hepatic microsomal cytochromes P-450c and P-450d. (1982) (92)
- A selective phosphatase of regenerating liver phosphatase inhibitor suppresses tumor cell anchorage-independent growth by a novel mechanism involving p130Cas cleavage. (2008) (91)
- Sex change in cytochrome P-450 phenotype by growth hormone treatment of adult rat hepatocytes maintained in a culture system on matrigel. (1988) (89)
- Characterization of nine monoclonal antibodies against rat hepatic cytochrome P-450c. Delineation of at least five spatially distinct epitopes. (1984) (89)
- The direct oxidation of ethanol by a catalase- and alcohol dehydrogenase-free reconstituted system containing cytochrome P-4501. (1978) (89)
- Identification of epoxide hydrase as the preneoplastic antigen in rat liver hyperplastic nodules. (1978) (88)
- Liver microsomal epoxide hydrase. (1977) (87)
- Comparison of the tumor-initiating activities of benzo(a)pyrene arene oxides and diol-epoxides. (1977) (86)
- Coinduction of multiple hepatic cytochrome P-450 proteins and their mRNAs in rats treated with imidazole antimycotic agents. (1989) (85)
- Carcinogenicity of benzo-ring derivatives of benzo(a)pyrene on mouse skin. (1977) (84)
- Mutagenic and cytotoxic activity of benzol[a]pyrene 4,5-, 7,8-, and 9,10-oxides and the six corresponding phenols. (1975) (84)
- Insecticide inhibition and stimulation of steroid hydroxylases in rat liver. (1967) (84)
- Tumorigenicity of optical isomers of the diastereomeric bay-region 3,4-diol-1,2-epoxides of benzo(c)phenanthrene in murine tumor models. (1986) (83)
- Biphasic decrease of radioactive hemoprotein from liver microsomal CO-binding particles. Effect of 3-methylcholanthrene. (1969) (82)
- An enantiomeric interaction in the metabolism and tumorigenicity of (+)- and (-)-benzo[a]pyrene 7,8-oxide. (1980) (81)
- Exceptionally high tumor-initiating activity of benzo(c)phenanthrene bay-region diol-epoxides on mouse skin. (1980) (78)
- Studies on microsomal hydroxylation and the demonstration of a new carbon monoxide binding pigment in liver microsomes. (1968) (77)
- Decreased central depressant effect of progesterone and other steroids in rats pretreated with drugs and insecticides. (1966) (76)
- Properties of purified liver microsomal cytochrome P450 from rats treated with the polychlorinated biphenyl mixture Aroclor 1254. (1977) (76)
- Mutagenicity and tumorigenicity of phenanthrene and chrysene epoxides and diol epoxides. (1979) (74)
- Effects of three recombinant human leukocyte interferons on drug metabolism in mice. (1982) (73)
- Distinct rat hepatic microsomal epoxide hydrolases catalyze the hydration of cholesterol 5,6 alpha-oxide and certain xenobiotic alkene and arene oxides. (1983) (73)
- The inducibility and catalytic activity of cytochromes P450c (P450IA1) and P450d (P450IA2) in rat tissues. (1990) (73)
- Alteration of the microsomal hemoprotein by 3-methylcholanthrene: effects of ethionine and actinomycin D. (1968) (72)
- Inducibility of benzo [α] pyrene hydroxylase in human skin by polycyclic hydrocarbons (1973) (72)
- Ethanol binding to hepatic microsomes. Its increase by ethanol consumption. (1971) (70)
- Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site. (2002) (70)
- Metabolism of benzo[a]pyrene. III. An evaluation of the fluorescence assay. (1975) (70)
- Identification and localization of amino acid substitutions between two phenobarbital-inducible rat hepatic microsomal cytochromes P-450 by micro sequence analyses. (1983) (70)
- Incorporation of radioactive- -aminolevulinic acid into microsomal cytochrome P 450 : selective breakdown of the hemoprotein by allylisopropylacetamide and carbon tetrachloride. (1972) (70)
- Tumorigenicity of five dihydrodiols of benz(a)anthracene on mouse skin: exceptional activity of benz(a)anthracene 3,4-dihydrodiol. (1977) (69)
- Use of monoclonal antibody probes against rat hepatic cytochromes P-450c and P-450d to detect immunochemically related isozymes in liver microsomes from different species. (1984) (69)
- Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds and endogenous substrates. VII. Stimulation of benzphetamine N-demethylation by lipid and detergent. (1974) (68)
- Monoclonal antibodies distinguish among isozymes of the cytochrome P-450b subfamily. (1985) (68)
- High mutageniticity of metabolically activated chrysene 1,2 dihydrodiol: evidence for bay region activation of chrysene. (1977) (67)
- Effect of phenobarbital and other drugs on the metabolism and uterotropic action of estradiol-17-beta and estrone. (1968) (67)
- Purification of a human liver cytochrome P-450 immunochemically related to several cytochromes P-450 purified from untreated rats. (1987) (65)
- Purification of liver microsomal cytochrome P-448 from 3-methylcholanthrene-treated rabbits. (1975) (65)
- NH2-terminal sequence analyses of four rat hepatic microsomal cytochromes P-450. (1984) (65)
- Stereospecificity of microsomal and purified epoxide hydrase from rat liver. Hydration of arene oxides of polycyclic hydrocarbons. (1977) (64)
- Differential time course of induction of rat liver microsomal cytochrome P-450 isozymes and epoxide hydrolase by Aroclor 1254. (1983) (64)
- Metabolic formation of 1,9,10-trihydroxy-9,10-dihydro-3-methylcholanthrene: a potential proximate carcinogen from 3-methylcholanthrene. (1978) (63)
- Metabolic activation of 3-methylcholanthrene and its metabolites to products mutagenic to bacterial and mammalian cells. (1978) (63)
- Accessibility of cytochrome P450 in microsomal membranes: inhibition of metabolism by antibodies to cytochrome P450. (1977) (63)
- Marked differences in the carcinogenic activity of optically pure (+)- and (-)-trans-7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene in newborn mice. (1978) (63)
- Partial purification and properties of cytochromes P-450 and P-448 from rat liver microsomes. (1972) (62)
- Mutagenicity and tumor-initiating activity of cyclopenta(c,d)pyrene and structurally related compounds. (1980) (62)
- Biological activity of benzo[e]pyrene. An assessment based on mutagenic activities and metabolic profiles of the polycyclic hydrocarbon and its derivatives. (1979) (61)
- 9 – Mutagenicity and Carcinogenicity of Benzo[a]pyrene and Benzo[a]pyrene Derivatives (1978) (61)
- Evidence for bay region activation of chrysene 1,2-dihydrodiol to an ultimate carcinogen. (1978) (61)
- Cytochromes P‐450 and bs in human liver microsomes (1969) (61)
- Effects of drugs and environmental chemicals on steroid metabolism (1973) (61)
- Metabolism of benzo[a]pyrene. Effect of 3-methylcholanthrene pretreatment on metabolism by microsomes from lungs of genetically "responsive" and "nonresponsive" mice. (1977) (60)
- Metabolic activation of dibenzo(a,h)anthracene and its dihydrodiols to bacterial mutagens. (1978) (60)
- The Bay Region Theory of Polycyclic Aromatic Hydrocarbon Carcinogenesis (1985) (60)
- Effect of enzyme inducers on substrate specificity of the cytochrome P-450's. (1973) (59)
- Multiple, immunoidentical forms of phenobarbital-induced rat liver cytochromes P-450 are encoded by different mRNAs. (1982) (58)
- High carcinogenicity of 2-hydroxybenzo(a)pyrene on mouse skin. (1977) (58)
- Hepatic microsomal epoxide hydrase. Involvement of a histidine at the active site suggests a nucleophilic mechanism. (1978) (57)
- Stereoselectivity of cytochrome P-450c in the formation of naphthalene and anthracene 1,2-oxides. (1984) (57)
- Tumorigenicity of enantiomers of chrysene 1,2-dihydrodiol and of the diastereomeric bay-region chrysene 1,2-diol-3,4-epoxides on mouse skin and in newborn mice. (1983) (56)
- Lack of carcinogenicity of 4-, 5-, 6-, 7-, 8-, 9-, and 10-hydroxybenzo(a)pyrene on mouse skin. (1976) (56)
- [11] Purification of cytochrome P-450 and P-448 from rat liver microsomes (1978) (56)
- Stimulatory effect of N-phenylbarbital (phetharbital) on cortisol hydroxylation in man. (1968) (56)
- 8 – The Bay-Region Theory of Carcinogenesis by Polycyclic Aromatic Hydrocarbons (1978) (55)
- The comparative metabolism of phenacetin and N‐acetyl‐p‐aminophenol in man, with particular reference to effects on the kidney (1968) (55)
- Tumorigenicity of bay-region epoxides and other derivatives of chrysene and phenanthrene in newborn mice. (1979) (55)
- Effect of chronic phenobarbital treatment on the liver microsomal metabolism and uterotropic action of 17-beta-estradiol. (1967) (54)
- Reactivity and tumorigenicity of bay-region diol epoxides derived from polycyclic aromatic hydrocarbons. (1986) (54)
- The in vivo turnover of rat liver microsomal epoxide hydrolase and both the apoprotein and heme moieties of specific cytochrome P-450 isozymes. (1983) (53)
- Breakdown of cytochrome P-450 heme by secobarbital and other allyl-containing barbiturates. (1973) (53)
- Mutagenicity of diol-epoxides and tetrahydroepoxides of benz(a)acridine and benz(c)acridine in bacteria and in mammalian cells. (1983) (51)
- High affinity phenacetin O-deethylase is catalysed specifically by cytochrome P450d (P450IA2) in the liver of the rat. (1990) (50)
- The rate of pentobarbital and acetanilide metabolism by liver microsomes: a function of lipid peroxidation and degradation of cytochrome P-450 heme. (1973) (49)
- Metabolism of trans-9,10-dihydroxy-9,10-dihydrobenzo[a]pyrene occurs primarily by arylhydroxylation rather than formation of a diol epoxide. (1978) (49)
- Exceptional carcinogenic activity of benz[a]anthracene 3,4-dihydrodiol in the newborn mouse and the bay region theory. (1978) (49)
- Destruction of Cytochrome P450 by Secobarbital and Other Barbiturates Containing Allyl Groups (1972) (48)
- Polypeptide patterns of hepatic microsomes from Long-Evans rats treated with different xenobiotics. (1982) (48)
- Liver microsomal electron transport systems. III. The involvement of cytochrome b5 in the NADPH-supported cytochrome P-450-dependent hydroxylation of chlorobenzene. (1974) (48)
- Species differences in the induction of microsomal hemoproteins and 3,4-benzpyrene hydroxylase by phenobarbital and 3-methylcholanthrene. (1970) (47)
- Metabolism of alpha-naphthoflavone and beta-naphthoflavone by rat liver microsomes and highly purified reconstituted cytochrome P-450 systems. (1983) (47)
- Hepatic cytochrome P-448 and epoxide hydrase: enzymes of nuclear origin are immunochemically identical with those of microsomal origin. (1979) (47)
- Rat hepatic cytochrome P-450 isozyme specificity for the metabolism of the steroid sulfate, 5α-androstane-3α,17β-diol-3,17-disulfate (1984) (46)
- Amino-terminal and carboxy-terminal sequence of hepatic microsomal cytochrome P-450d, a unique hemoprotein from rats treated with isosafrole. (1982) (46)
- A low-temperature EPR study of partially purified, soluble ferric cytochromes P-450 and P-448 from rat liver microsomes. (1973) (46)
- Liver microsomal electron transport systems. II. The involvement of cytochrome b5 in the NADH-dependent hydroxylation of 3,4-benzpyrene by a reconstituted cytochrome P-448-containing system. (1974) (45)
- Induction of the male-specific cytochrome P450 3A2 in female rats by phenytoin. (1996) (45)
- Decreased uterotropic potency of oral contraceptives in rats pretreated with phenobarbital. (1968) (45)
- X‐ray structure of a novel matrix metalloproteinase inhibitor complexed to stromelysin (2001) (45)
- Metabolism of benzo[a]anthracene to its tumorigenic 3,4-dihydrodiol. (1979) (44)
- Role of Purified Cytochrome P-448 and Epoxide Hydrase in the Activation and Detoxification of Benzo[a]pyrene (1977) (44)
- Skin tumor-initiating activities of the twelve isomeric phenols of benzo(a)pyrene. (1978) (44)
- Mechanism of androstenedione formation from testosterone and epitestosterone catalyzed by purified cytochrome P-450b. (1988) (44)
- Carcinogenicity of Polycyclic Aromatic Hydrocarbons: The Bay-Region Theory (1980) (43)
- Mutagenicity of the enantiomers of the diastereomeric bay-region benzo(c)phenanthrene 3,4-diol-1,2-epoxides in bacterial and mammalian cells. (1983) (42)
- Stimulatory effect of polycyclic hydrocarbons and aromatic azo derivatives on the metabolism of 7,12-dimethylbenz(alpha)anthracene. (1967) (42)
- Isozyme specificity of testosterone 7 alpha-hydroxylation in rat hepatic microsomes: is cytochrome P-450a the sole catalyst? (1987) (42)
- In vitro Reactions of the Diastereomeric 9,10-Epoxides of (+) and (—)-trans-7,8-Dihydroxy-7,8-dihydrobenzo-[a]pyrene with Polyguanylic Acid and Evidence for Formation of an Enantiomer of Each Diastereomeric 9,10-Epoxide from Benzo[a]pyrene in Mouse Skin (1977) (42)
- Absolute stereochemistry of the trans-dihydrodiols formed from benzo[a]anthracene by liver microsomes. (1979) (42)
- Inhibitory effect of phenobarbital or chlordane pretreatment on the androgen-induced increase in seminal vesicle weight in the rat. (1969) (42)
- Neonatal imprinting and the turnover of microsomal cytochrome P-450 in rat liver. (1975) (42)
- Differential stereoselectivity of cytochromes P-450b and P-450c in the formation of naphthalene and anthracene 1,2-oxides. The role of epoxide hydrolase in determining the enantiomer composition of the 1,2-dihydrodiols formed. (1985) (41)
- Mutagenicity of the dihydrodiols and bay-region diol-epoxides of benzo(c)phenanthrene in bacterial and mammalian cells. (1980) (41)
- Effects of piperonyl butoxide on drug metabolism in rodents and man. (1972) (41)
- The highly tumorigenic 3,4-dihydrodiol is a principal metabolite formed from dibenzo[a,h]anthracene by liver enzymes. (1979) (40)
- Purification of human liver microsomal epoxide hydrase. Differences in the properties of the human and rat enzymes. (1979) (40)
- Metabolism of benzo[c]phenanthrene by rat liver microsomes and by a purified monooxygenase system reconstituted with different isozymes of cytochrome P-450. (1983) (40)
- Tumorigenicity of the diastereomeric benz[a]anthracene 3,4-diol-1,2-epoxides and the (+)- and (-)-enantiomers of benz[a]anthracene 3,4-dihydrodiol in newborn mice. (1979) (38)
- Comparison of the hydroxylation of zoxazolamine and benzo[a]pyrene in human placenta: Effect of cigarette smoking (1976) (38)
- Liver microsomal epoxide hydrase: activation, inhibition, and immunological properties of the purified enzyme. (1978) (38)
- Stimulatory effect of phenobarbital on the metabolism in vivo of estradiol-17-beta and estrone in the rat. (1968) (38)
- Stereoselectivity of rat liver cytochrome P-450c on formation of benzo[a]pyrene 4,5-oxide. (1981) (37)
- Assay and partial purification of epoxide hydrase from rat liver microsomes. (1974) (36)
- Reconstitution of the reduced nicotinamide adenine dinucleotide phosphate- and reduced nicotinamide adenine dinucleotide-peroxidase activities from solubilized components of rat liver microsomes. (1975) (36)
- Hepatic microsomal epoxide hydrolase. Mechanistic studies of the hydration of K-region arene oxides. (1980) (36)
- Enantioselectivity of microsomal epoxide hydrolase toward arene oxide substrates. (1981) (36)
- Administration of 3-methylcholanthrene to rats increases the specific hybridizable mRNA coding for cytochrome P-450c. (1981) (36)
- Epidermal hyperplasia after topical application of benzo (a) pyrene, benzo (a) pyrene diol epoxides, and other metabolites. (1977) (35)
- Effect of a 6-fluoro substituent on the metabolism and biological activity of benzo(a)pyrene. (1983) (35)
- The accumulation of distinct mRNAs for the immunochemically related cytochromes P-450c and P-450d in rat liver following 3-methylcholanthrene treatment. (1983) (34)
- SPECIFICITY IN THE REGULATION OF THE 6β-, 7α AND 16α-HYDROXYLATION OF TESTOSTERONE BY RAT LIVER MICROSOMES (1969) (34)
- Hydration of arene and alkene oxides by epoxide hydrase in human liver microsomes (1977) (34)
- Tumor-initiating activity of benz[c]acridine and twelve of its derivatives on mouse skin. (1983) (34)
- Tumorigenicity of the dihydrodiols of dibenzo(a,h)anthracene on mouse skin and in newborn mice. (1979) (34)
- Effect of storage of frozen liver microsomal preparations on the hydroxylation of testosterone and pentobarbital and the N-demethylation of ethylmorphine. (1969) (34)
- THE ROLE OF CYTOCHROME P‐450 AND P‐448 IN DRUG AND STEROID HYDROXYLATIONS (1973) (34)
- BENZO(A)PYRENE 7,8-DIHYDRODIOL IS MORE CARCINOGENIC THAN BENZO(A)PYRENE IN NEWBORN MICE (1977) (33)
- Stereoselective metabolism of the (+)- and (-)-enantiomers of trans-3,4-dihydroxy-3,4-dihydrobenz[a]anthracene by rat liver microsomes and by a purified and reconstituted cytochrome P-450 system. (1982) (33)
- Tumorigenic activity of 3-methylcholanthrene metabolites on mouse skin and in newborn mice. (1979) (32)
- Role of diaxial versus diequatorial hydroxyl groups in the tumorigenic activity of a benzo[a]pyrene bay-region diol epoxide. (1987) (32)
- Stereoselective metabolism of the (+)-(S,S)- and (-)-(R,R)-enantiomers of trans-3,4-dihydroxy-3,4-dihydrobenzo[c]-phenanthrene by rat and mouse liver microsomes and by a purified and reconstituted cytochrome P-450 system. (1986) (31)
- Evidence for a family of four immunochemically related isozymes of cytochrome P-450 purified from untreated rats. (1985) (31)
- Immunohistochemical localization of cytochrome P-450a in liver sections from untreated rats and rats treated with phenobarbital or 3-methylcholanthrene. (1983) (31)
- Tumorigenicity of bay-region diol-epoxides and other benzo-ring derivatives of dibenzo(a,h)pyrene and dibenzo(a,i)pyrene on mouse skin and in newborn mice. (1982) (30)
- Interleukin-1 beta induces cytosolic phospholipase A2 and prostaglandin H synthase in rheumatoid synovial fibroblasts. Evidence for their roles in the production of prostaglandin E2. (1994) (29)
- Studies on bilirubin and steroid glucuronidation by rat liver microsomes. (1975) (29)
- Tumorigenicity of dihydrodiols and diol-epoxides of benz[c]acridine in newborn mice. (1984) (29)
- Stereoselective Metabolic Activation of Polycyclic Aromatic Hydrocarbons (1979) (29)
- Properties of liver microsomal cholesterol 5,6-oxide hydrolase. (1985) (28)
- Co-induction of cytochrome P-450 isozymes in rat liver by 2,4,5,2',4',5'-hexachlorobiphenyl or 3-methoxy-4-aminoazobenzene. (1987) (28)
- Inhibition by CO of hepatic benzo[a]pyrene hydroxylation and its reversal by monochromatic light. (1977) (28)
- Stereoselective formation of benz[a]anthracene (+)-(5S,6R)-oxide and (+)-(8R,9S)-oxide by a highly purified and reconstituted system containing cytochrome P-450c. (1982) (28)
- Synthesis of liver cytochrome P-450b in a cell-free protein synthesizing system. (1979) (28)
- High stereoselectivity among the optical isomers of the diastereomeric bay-region diol-epoxides of benz(a)anthracene in the expression of tumorigenic activity in murine tumor models. (1984) (28)
- Absolute configurations of the arene oxide, trans-dihydrodiol and cis-dihydeodiol products resulting from metabolism of quinoline at the 5,6-bond (1991) (28)
- Mutagenicity of benzo(e)pyrene and triphenylene tetrahydroepoxides and diol-epoxides in bacterial and mammalian cells. (1980) (27)
- Mutagenicity of the bay-region diol-epoxides and other benzo-ring derivatives of dibenzo(a,h)pyrene and dibenzo(a,i)pyrene. (1981) (27)
- Polyclonal and monoclonal antibodies as probes of rat hepatic cytochrome P-450 isozymes. (1987) (27)
- Hepatic microsomal epoxide hydrase. Chemical evidence for a single polypeptide chain. (1979) (27)
- Stereoselectivity of microsomal epoxide hydrolase toward diol epoxides and tetrahydroepoxides derived from benz[a]anthracene. (1985) (27)
- Human group II phospholipase A2. Characterization of monoclonal antibodies and immunochemical quantitation of the protein in synovial fluid. (1991) (27)
- Biological Activity of Polycyclic Hydrocarbon Metabolites and the Bay Region Theory (1979) (26)
- Metabolism of benzo(e)pyrene by rat liver microsomal enzymes. (1980) (26)
- Differences in mutagenicity and cytotoxicity of (+)- and (-)-benzo[a]pyrene 4,5-oxide: a synergistic interaction of enantiomers. (1979) (26)
- The 1988 Bernard B. Brodie Award lecture. Functional diversity of hepatic cytochromes P-450. (1990) (26)
- Metabolism and tumorigenicity of 7-, 8-, 9-, and 10-fluorobenzo(a)pyrenes. (1982) (26)
- A highly sensitive radiometric assay for zoxazolamine hydroxylation by liver microsomal cytochrome P-450 and P-448: properties of the membrane-bound and purified reconstituted system. (1976) (25)
- Tumorigenic activity of benzo(e)pyrene derivatives on mouse skin and in newborn mice. (1980) (25)
- The crystal structure of human muscle glycogen phosphorylase a with bound glucose and AMP: An intermediate conformation with T‐state and R‐state features (2006) (25)
- Formation of a thiomethyl metabolite of phenacetin and acetaminophen in dogs and man (1978) (25)
- Characterization of partially purified cytochromes P-450 and P-448 from rat liver microsomes. (1973) (25)
- Stereoselective metabolism of the (+)- and (-)-enantiomers of trans-1,2-dihydroxy-1,2-dihydrochrysene to bay-region 1,2-diol-3,4-epoxide diastereomers by rat liver enzymes. (1982) (25)
- Tumor initiating and promoting activities of various benzo(a)pyrene metabolites in mouse skin (1977) (25)
- Age- and Gender-Related Expression of Rat Liver Cytochrome P450 (1993) (24)
- Mutagenicity of the optical isomers of the diastereomeric bay-region chrysene 1,3-diol-3,4-epoxides in bacterial and mammalian cells. (1982) (24)
- Structural requirements for the metabolic activation of benzo[a]pyrene to mutagenic products: effects of modifications in the 4,5-, 7,8-, and 9,10-positions. (1977) (24)
- Evidence for concerted kinetic oxidation of progesterone by purified rat hepatic cytochrome P-450g. (1988) (24)
- Highly tumorigenic bay-region diol epoxides from the weak carcinogen benzo[c]phenanthrene. (1981) (24)
- Biphasic decrease of radioactive hemoprotein from liver microsomal carbon monoxide-binding particles. Effect of phenobarbital and chlordane. (1969) (23)
- Bacterial and mammalian cell mutagenicity of four optically active bay-region 3,4-diol-1,2-epoxides and other derivatives of the nitrogen heterocycle dibenz[c,h]acridine. (1986) (23)
- Increased liver microsomal androgen metabolism by phenobarbital: correlation with decreased androgen action on the seminal vesicles of the rat. (1974) (23)
- Crystal Structure of Human Liver Glucokinase Bound to a Small Molecule Allosteric Activator (2004) (23)
- Mechanism of inactivation of rat liver microsomal cytochrome P-450c by 2-bromo-4'-nitroacetophenone. (1986) (23)
- Immunocytochemical localization of epoxide hydrase in hyperplastic nodules induced in rat liver by 2-acetylaminofluorene. (1979) (22)
- Induction of aryl hydrocarbon hydroxylase in human skin. (1973) (22)
- Multiplicity of liver microsomal cytochrome P-450: separation, purification and characterization. (1975) (21)
- Effect of carbon tetrachloride and other inhibitors of drug metabolism on the metabolism and action of estradiol-17 beta and estrone in the rat. (1970) (20)
- Effects of a 6-fluoro substituent on the metabolism of benzo(a)pyrene 7,8-dihydrodiol to bay-region diol epoxides by rat liver enzymes. (1984) (20)
- High-throughput methods for measuring heparanase activity and screening potential antimetastatic and anti-inflammatory agents. (2004) (19)
- Comparisons of highly purified hepatic microsomal cytochromes P-450 from Holtzman and Long-Evans rats. (1982) (19)
- Microheterogeneity of a male-specific rat hepatic cytochrome P-450: existence of three allozymic forms. (1985) (19)
- A regulatory polymorphism for rat hepatic cytochrome P-450g. (1987) (19)
- Comparison of nuclear and microsomal epoxide hydrase from rat liver. (1979) (19)
- Carcinogenicity of benzo[a]pyrene and thirteen of its derivatives in C3H/fCum mice. (1980) (19)
- On the glycosylation state of five rat hepatic microsomal cytochrome P-450 isozymes. (1983) (18)
- Tumorigenicity of the diastereomeric bay-region benzo(e)pyrene 9,10-diol-11,12-epoxides in newborn mice. (1981) (18)
- Carcinogenicity of 2-hydroxybenzo(a)pyrene and 6-hydroxybenzo(a)pyrene in newborn mice. (1979) (18)
- Regio- and stereoselectivity of hepatic cytochrome P-450 toward polycyclic aromatic hydrocarbon substrates. (1981) (17)
- THE EFFECTS OF 3-METHYLCHOLANTHRENE AND PHENOBARBITAL ON LIVER MICROSOMAL HEMOPROTEINS AND ON THE HYDROXYLATION OF BENZPYRENE (1969) (17)
- Stereoselective metabolism of polycyclic aromatic hydrocarbons to carcinogenic metabolites (1985) (17)
- Mouse skin tumor-initiating activity of 5-, 7-, and 12-methyl- and fluorine-substituted benz[a]anthracenes. (1982) (17)
- Stereo-selectivity and regio-selectivity in the metabolism of 7,8-dihydrobenzo[a]pyrene by cytochrome P450, epoxide hydrolase and hepatic microsomes from 3-methylcholanthrene-treated rats. (1995) (17)
- Chemical modification and inactivation of rat liver microsomal cytochrome P-450c by 2-bromo-4'-nitroacetophenone. (1986) (17)
- Mutagenicity of dihydrodiols and diol epoxides of dibenz[a, h]acridine in bacterial and mammalian cells. (1989) (17)
- 7-Dehydrocholesterol 5,6 beta-oxide as a mechanism-based inhibitor of microsomal cholesterol oxide hydrolase. (1986) (16)
- The primary structure of cytochrome P-450d purified from rat liver microsomes: prediction of helical regions and domain analysis. (1986) (16)
- Species-specific enhancement by 7,8-benzoflavone of hepatic microsomal metabolism of benzo[e]pyrene 9,10-dihydrodiol to bay-region diol epoxides. (1981) (16)
- Metabolism and Biological Activity of Benzo[a]pyrene and Its Metabolic Products (1977) (16)
- High tumorigenicity of the 3,4-dihydrodiol of 7-methylbenz[c]acridine on mouse skin and in newborn mice. (1986) (16)
- Purification and assay of liver microsomal epoxide hydrase. (1978) (15)
- Nucleolar cytochrome P-450. (1980) (15)
- CHARACTERIZATION OF MULTIPLE FORMS OF HIGHLY PURIFIED CYTOCHROME P-450 FROM THE LIVER MICROSOMES OF RATS, MICE AND RABBITS (1977) (15)
- Role of sulfhydryl gropus in the hydroxylation of benzo[a]pyrene by purified rat and rabbit cytochrome P-448. (1977) (15)
- Antibodies as probes of cytochrome P450 isozymes. (1986) (14)
- Testosterone inhibition of 6β-, 7α- and 16α-hydroxytestosterone metabolism by rat liver microsomes☆ (1969) (14)
- Human liver microsomal epoxide hydrolase. Correlation of immunochemical quantitation with catalytic activity. (1982) (14)
- Tumorigenicity of benzo[alpha]pyrene 4,5-,7,8-,9,10- and 11,12-oxides in newborn mice. (1978) (14)
- Multiplicity and functional diversity of rat hepatic microsomal cytochrome P450 isozymes (1984) (14)
- Fluorine substitution as a probe for the role of the 6-position of benzo[a]pyrene in carcinogenesis. (1983) (14)
- Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds, and endogenous substrates. IV. Hydroxylation of aniline. (1972) (14)
- Monoclonal antibodies of differentiating specificities as probes of cytochrome P450h (2C11). (1993) (13)
- The molecular cloning of cytochrome P-450c information. (1981) (13)
- PURIFICATION OF LIVER MICROSOMAL CYTOCHROME P-450: HOPES AND PROMISES (1977) (12)
- Intranuclear localization of hepatic cytochrome P448 by an immunochemical method. (1979) (12)
- Induction of hepatic 7,12-dimethylbenz(alpha)anthracene metabolism by polycyclic aromatic hydrocarbons and aromatic azo derivatives. (1966) (12)
- Effects of a 6-Fluoro Substituent on the Solvolytic Properties of the Diastereomeric 7,8-Diol 9,10-Epoxides of the Carcinogen Benzo[a]pyrene (1987) (12)
- Distribution of radioactive hemoprotein and CO-binding pigment in rough and smooth endoplasmic reticulum of rat liver. (1970) (11)
- Stereoselective monooxygenation of carcinostatic 1-(2-chloroethyl)-3-(cyclohexyl)-1-nitrosourea and 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea by purified cytochrome P-450 isozymes. (1984) (11)
- Absolute configuration of the 5,6-oxide formed from 7,12-dimethylbenz[a]anthracene by cytochrome P450c. (1985) (11)
- Effect of 3-methylcholanthrene treatment on phenacetin O-dealkylation in several inbred mouse strains. (1975) (11)
- Carcinogenicity of benzo[a]pyrene derivatives: the bay region theory (1978) (11)
- The effect of steric strain in the bay-region of polycyclic aromatic hydrocarbons: tumorigenicity of alkyl-substituted benz[a]anthracenes. (1983) (11)
- Induction of rat liver microsomal cytochrome P-450 isozymes and epoxide hydrolase by a series of 4'-substituted-2,3,4,5-tetrachlorobiphenyls. (1988) (10)
- Structural analysis of the cysteine-containing peptides from the major 3-methylcholanthrene-induced isozyme of cytochrome P-450 (P-450c) in rat liver microsomes. (1984) (10)
- Structures of cysteine-containing peptides in isosafrole-inducible rat hepatic microsomal cytochrome P-450d: sequence homology with 3-methylcholanthrene-induced cytochrome P-450c. (1984) (10)
- Human hepatic microsomal epoxide hydrolase. A structural comparison with the rat enzyme. (1982) (10)
- Stereoselective formation of benzo(c)phenanthrene (+)-(3S,4R) and (+)-(5S,6R)-oxides by cytochrome P450c in a highly purified and reconstituted system. (1987) (10)
- Regioselectivity and stereoselectivity in the metabolism of trans-1,2-dihydroxy-1,2-dihydrobenz[a]anthracene by rat liver microsomes. (1983) (10)
- Mutagenicity of the enantiomers of the diastereomeric bay-region benz(a)anthracene 3,4-diol-1,2-epoxides in bacterial and mammalian cells. (1983) (9)
- Purification of recombinant human secretory phospholipase A2 (group II) produced in long-term immobilized cell culture. (1992) (9)
- Apparent anomalies in the resolution of cytochrome P-450 isoenzymes by gel electrophoresis. (1984) (9)
- Inability of substrates to alter the carbon monoxide and ethyl isocyanide difference spectra of microsomal hemoprotein. (1971) (9)
- Stimulatory effect of phenobarbital on the metabolism of the oral contraceptive 17 alpha-ethynylestradiol-3-methyl ether (mestranol) by rat liver microsomes. (1979) (9)
- Role of cytochrome b5 in NADPH-and NADH-dependent hydroxylation by the reconstituted cytochrome P-450- or P-448-containing system. (1975) (8)
- Purification of cytochrome P-450 and P-448 from rat liver microsomes. (1978) (8)
- Metabolism of (-)-trans-(3R, 4R)-dihydroxy-3,4-dihydrochrysene to diol epoxides by liver microsomes. (1981) (8)
- Mutagenicityand Cytotoxicityof Benzo(a)pyreneBenzo-Ring Epoxides (1976) (7)
- A generic time-resolved fluorescence assay for serine/threonine kinase activity: application to Cdc7/Dbf4. (2003) (7)
- Chromatography of radioactive microsomal hemoproteins on diethylaminoethyl cellulose. (1971) (7)
- BAY-REGION ACTIVATION OF POLYCYCLIC AROMATIC HYDROCARBONS TO ULTIMATE MUTAGENS AND CARCINOGENS (1980) (6)
- Partial purification and separation of multiple forms of cytochrome. P-450 and cytochrome P-448 from rat liver microsomes. (1975) (6)
- Characterization and Regulation of Rat Hepatic Microsomal Cytochrome P‐450 Isozymes (1984) (6)
- Rat hepatic cytochrome P-450 isozyme specificity for the metabolism of the steroid sulfate, 5 alpha-androstane-3 alpha, 17 beta-diol-3,17-disulfate. (1984) (6)
- Studies on the incorporation of delta-aminolevulinic acid into microsomal hemoprotein: effect of 3-methylcholanthrene and phenobarbital. (1969) (6)
- Studies on the spin state of 3-methylcholanthrene induced cytochrome P-450 from rat liver. (1975) (5)
- EVIDENCE FOR THE DIRECT INVOLVEMENT OF HEPATIC CYTOCHROME P450 IN ETHANOL METABOLISM (1977) (4)
- Metabolism and Biological Activity (1977) (4)
- PROPERTIES OF LIVER MICROSOMAL CYTOCHROME P450 FROM RATS TREATED WITH ISOSAFROLE (1980) (4)
- n-Octylamine difference spectra of cytochromes P-450 and P-448 from rat and mouse liver: a species difference. (1973) (4)
- Specificity of antisera directed against rat liver cytochrome P-448. (1974) (4)
- Stereoselective metabolism of the optical isomers of trans-1,2-dihydroxy-1,2-dihydrophenanthrene to bay-region diol epoxides by rat liver microsomes. (1982) (4)
- Pharmacological and Toxicological Implications of Multiple Cytochromes P-450 (1982) (4)
- CHARACTERIZATION AND REGULATION OF RAT LIVER MICROSOMAL CYTOCHROME P450 (1981) (3)
- METABOLIC FORMATION OF 1,9,10-TRIHYDROXY-9,10-DIHYDRO-3-METHYLCHOLANTHRENE- A POTENTIAL PROXIMATE CARCINOGEN FROM 3-METHYLCHOLANTHRENE (1978) (3)
- Differential stereoselectivity on metabolism of triphenylene by cytochromes P-450 in liver microsomes from 3-methylcholanthrene- and phenobarbital-treated rats. (1988) (3)
- CHARACTERIZATION OF THREE FORMS OF RAT HEPATIC CYTOCHROME P450: EVIDENCE FOR SEPARATE GENE PRODUCTS (1980) (3)
- Interleukin-1β induces cytosolic PLA2 in parallel with prostaglandin E2 in rheumatoid synovial fibroblasts (2005) (3)
- Mutagenicityand Cytotoxicityof Benzo(a)pyreneArene Oxides, Phenols,Quinones, and Dihydrodiolsin Bacterial and Mammalian Cells (1976) (3)
- Appendix I – Update to Vol. IIA: Polycyclic Aromatic Hydrocarbons and Carcinogenesis: The Bay-Region Theory (1982) (2)
- IMMUNOCHEMICAL QUANTITATION OF THREE FORMS OF HEPATIC CYTOCHROME P450 IN RATS: EFFECTS OF AGE AND INDUCTION (1980) (2)
- Metabolism of dibenz[c,h]acridine by rat liver microsomes and by cytochrome P450c with and without epoxide hydrolase (1985) (2)
- High carcinogenicity of 2-hydroxybenzo[a]pyrene (2-hobp) on mouse skin. Abstr. (1977) (1)
- Stereoselective metabolism of (+)- and (-)-benzo(a)anthracene 3,4-dihydrodiols by rat liver microsomes and a reconstituted cytochrome P-450 system (1981) (1)
- Effects of inducers of liver microsomal enzymes on the composition of microsomal hemoprotein. (1971) (1)
- CATALYTIC PROPERTIES OF MICROSOMAL AND PURIFIED EPOXIDE HYDROLASE TOWARD K-REGION ARENE OXIDES (1980) (1)
- Crystal Structure of Human Muscle Glycogen Phosphorylase a with AMP and Glucose (2006) (1)
- 9,10-Dihydrodiols of 1-hydroxy-3-methylcholanthrene: potential proximate carcinogens derived from 3-methylcholanthrene (1978) (1)
- Inhibition of the acute toxicity and adrenocorticolytic effect of 7,12-dimethylbenz(a)anthracene by isopropylvaleramide and allylisopropylacetamide in the rat. (1975) (1)
- Comparisonof the Tumor-initiatingActivitiesof Benzo(a)pyreneArene Oxides and Diol-Epoxides1 (1977) (1)
- Regulation of rat liver cytochrome P450j, a high affinity N-nitrosodimethylamine demethylase (NDMAD) (1987) (1)
- Metabolism of triphenylene by liver microsomes from control, phenobarbital(PB)-treated and 3-methylcholanthrene(MC)-treated rats (1985) (1)
- 12 – Stereoselective Metabolic Activation of Polycyclic Hydrocarbons (1978) (0)
- Testosterone inhibition of 6beta-, 7alpha- and 16alphahydroxytestosterone metabolism by rat liver microsomes. (1969) (0)
- The effect of cytochrome P-450p-TAO complex formation on in vitro and in vivo hexachlorobenzene metabolism and toxicity. (1989) (0)
- Characterization and regulation of the hepatic microsomal mixed-function oxidase system (1984) (0)
- The induction of a carcinogen-metabolizing enzyme in human skin. (1973) (0)
- Spelunking stromelysin: a case history of structure-based drug design (1996) (0)
- Regulation of cytochrome P-450j in rat hepatocytes in vivo and in primry monolayer culture (1987) (0)
- 11 – BIOLOGICAL ACTIVITY OF POLYCYCLIC HYDROCARBON METABOLITES AND THE BAY REGION THEORY (1978) (0)
- Metabolism of benzo(c)chrysene by rat liver enzymes (1987) (0)
- PAH carcinogenesis: the bay region theory (1980) (0)
- Tumorigenicity oftheoptical enantiomers ofthediastereomeric benzo(a)pyrene 7,8-diol-9,10-ep oxides (1978) (0)
- Immunocytochemical localization ofepoxide hydrase inhyperplastic nodules induced inratliver by2-acetylaminoflu (1979) (0)
- 381 – INHIBITION BY IS0PR0PYLVALERAMIDE (IVA) AND ALLYLISOPROPYLACETAMIDE (AIA) OF HYDROCARBON-INDUCED T0XICITY AND IN VITRO MALIGNANT TRANSFORMATION (1977) (0)
- Effects of drugs on the metabolism of bilirubin and other normal body constituents. (1976) (0)
- Mouse Skin Tumor-Initiating Activity of 5-, 7-, and 12-Methyl-and Fluorine-Substituted 8 enz [ a ] (2012) (0)
- Novel stereoselectivity of rat liver cytochrome(s) P450 toward enantiomers of the trans-1,2-dihydrodiol of triphenylene. (1991) (0)
- Effects of a 6‐Fluoro Substituent on the Solvolytic Properties of the Diastereomeric 7,8‐Diol 9,10‐Epoxides of the Carcinogen Benzo(a)pyrene. (1987) (0)
- Absolute stereochemistry of the trans dihydrodiols formed from benzo[a]anthracene (BA) by rat liver microsomes (1979) (0)
- Tumorigenicityof Dihydrodiolsand Diol-Epoxidesof Benz(c)acridinein NewbornMice (1984) (0)
- Tumorigenicityof Bay-RegionEpoxideSand Other Derivativesof Chrysene and Phenanthrenein NewbornMice (2006) (0)
- PEPCK complex with PEP (2002) (0)
- PEPCK complex with nonhydrolyzable GTP analog, native data (2002) (0)
- Mechanism of Inactivation of Rat Liver Microsomal (1986) (0)
- CARCINOGENICITY OF BENZO(A)PYRENE DERIVATIVES: THE BAY REGION THEORY (1979) (0)
- Table 3. Immunohistochemical localization of four cytochrome P- 450 isoenzymes (PB,, PB,, MC, and MC,) GSTs B and C 'type' (GST B, GST C) epoxide hydrolase and P-450 reductase in the livers of control, PB- and 3-MC-treated rats (1984) (0)
- IN VITRO SYNTHESIS OF HEPATIC MICROSOMAL CYTOCHROME P-450 (1980) (0)
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